TreeWAS – Variant ID: rs405509

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F03 Unspecified dementia	1.000	0.000	0.000
F00-F09 Organic, including symptomatic, mental disorders	1.000	0.000	0.000
F00 Dementia in Alzheimer's disease	1.000	0.000	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	1.000	0.000	0.000
F01 Vascular dementia	0.992	0.008	0.000
F01.9 Vascular dementia, unspecified	0.985	0.015	0.000
G30.9 Alzheimer's disease, unspecified	0.979	0.021	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.950	0.050	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.909	0.091	0.000
G30 Alzheimer's disease	0.899	0.101	0.000
F06.7 Mild cognitive disorder	0.889	0.111	0.000
F02 Dementia in other diseases classified elsewhere	0.810	0.190	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.805	0.195	0.000
F09 Unspecified organic or symptomatic mental disorder	0.796	0.204	0.000
G30.0 Alzheimer's disease with early onset	0.794	0.206	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.790	0.210	0.000
G30.8 Other Alzheimer's disease	0.787	0.213	0.000
F01.1 Multi-infarct dementia	0.757	0.243	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.756	0.244	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.746	0.254	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.729	0.271	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.717	0.283	0.000
F01.8 Other vascular dementia	0.711	0.289	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.711	0.289	0.000
F01.2 Subcortical vascular dementia	0.711	0.289	0.000
F01.0 Vascular dementia of acute onset	0.711	0.289	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.709	0.291	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.703	0.297	0.000
G30.1 Alzheimer's disease with late onset	0.688	0.312	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.681	0.318	0.000
F06.5 Organic dissociative disorder	0.681	0.318	0.000
F06.4 Organic anxiety disorder	0.681	0.318	0.000
F06.3 Organic mood [affective] disorders	0.681	0.318	0.000
F06.1 Organic catatonic disorder	0.681	0.318	0.000
F06.0 Organic hallucinosis	0.681	0.318	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.670	0.330	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.636	0.364	0.000
F02.0 Dementia in Pick's disease	0.617	0.383	0.000
F07.2 Postconcussional syndrome	0.601	0.399	0.000
F07.0 Organic personality disorder	0.594	0.406	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.581	0.419	0.000
F02.2 Dementia in Huntington's disease	0.581	0.419	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.581	0.419	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.577	0.423	0.000
F07.1 Postencephalitic syndrome	0.577	0.423	0.000
F05.8 Other delirium	0.550	0.450	0.000
F02.3 Dementia in Parkinson's disease	0.545	0.455	0.000
F05.1 Delirium superimposed on dementia	0.536	0.464	0.000
G30-G32 Other degenerative diseases of the nervous system	0.524	0.476	0.000
F05.0 Delirium not superimposed on dementia, so described	0.484	0.516	0.000
F05.9 Delirium, unspecified	0.438	0.562	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.430	0.570	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.393	0.607	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.375	0.625	0.000
E78.0 Pure hypercholesterolaemia	0.334	0.666	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.671	0.329
N85.4 Malposition of uterus	0.000	0.678	0.322
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.682	0.318
N85.2 Hypertrophy of uterus	0.000	0.685	0.315
G31.0 Circumscribed brain atrophy	0.313	0.687	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.308	0.692	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.299	0.701	0.000
G31.8 Other specified degenerative diseases of nervous system	0.295	0.705	0.000
G31.2 Degeneration of nervous system due to alcohol	0.290	0.710	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.282	0.718	0.000
N85.7 Haematometra	0.000	0.768	0.231
N85.5 Inversion of uterus	0.000	0.772	0.228
N85.3 Subinvolution of uterus	0.000	0.772	0.228
N85.6 Intra-uterine synechiae	0.000	0.812	0.188
N85.1 Endometrial adenomatous hyperplasia	0.000	0.857	0.142
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.867	0.133
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.102	0.898	0.000
E78.1 Pure hyperglyceridaemia	0.092	0.907	0.000
E78.6 Lipoprotein deficiency	0.087	0.913	0.000
E78.3 Hyperchylomicronaemia	0.076	0.924	0.000
E78.4 Other hyperlipidaemia	0.073	0.927	0.000
E78.8 Other disorders of lipoprotein metabolism	0.072	0.928	0.000
I49.3 Ventricular premature depolarisation	0.000	0.930	0.070
E78.2 Mixed hyperlipidaemia	0.069	0.931	0.000
Chapter VI Diseases of the nervous system	0.046	0.954	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.046	0.954	0.000
G12 Spinal muscular atrophy and related syndromes	0.043	0.957	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.957	0.043
G11 Hereditary ataxia	0.041	0.959	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.041	0.959	0.000
G12.2 Motor neuron disease	0.041	0.959	0.000
G82 Paraplegia and tetraplegia	0.040	0.960	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.038	0.962	0.000
G11.9 Hereditary ataxia, unspecified	0.038	0.962	0.000
G70-G73 Diseases of myoneural junction and muscle	0.037	0.963	0.000
G20-G26 Extrapyramidal and movement disorders	0.037	0.963	0.000
G82.4 Spastic tetraplegia	0.035	0.965	0.000
G82.5 Tetraplegia, unspecified	0.035	0.965	0.000
G82.1 Spastic paraplegia	0.034	0.966	0.000
G11.1 Early-onset cerebellar ataxia	0.032	0.968	0.000
G25 Other extrapyramidal and movement disorders	0.032	0.968	0.000
G14 Postpolio syndrome	0.031	0.968	0.000
G10 Huntington's disease	0.031	0.969	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.031	0.969	0.000
G12.9 Spinal muscular atrophy, unspecified	0.031	0.969	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.031	0.969	0.000
G12.1 Other inherited spinal muscular atrophy	0.031	0.969	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.031	0.969	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.030	0.970	0.000
G81 Hemiplegia	0.030	0.970	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.030	0.970	0.000
G11.8 Other hereditary ataxias	0.030	0.970	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.030	0.970	0.000
G11.2 Late-onset cerebellar ataxia	0.030	0.970	0.000
G11.0 Congenital nonprogressive ataxia	0.030	0.970	0.000
G80 Infantile cerebral palsy	0.030	0.970	0.000
G21 Secondary Parkinsonism	0.029	0.970	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.029	0.971	0.000
G82.3 Flaccid tetraplegia	0.029	0.971	0.000
G82.0 Flaccid paraplegia	0.029	0.971	0.000
G24 Dystonia	0.029	0.971	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.029	0.971	0.000
G82.2 Paraplegia, unspecified	0.029	0.971	0.000
G72 Other myopathies	0.029	0.971	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.029	0.971	0.000
G03 Meningitis due to other and unspecified causes	0.028	0.971	0.000
G11.4 Hereditary spastic paraplegia	0.028	0.972	0.000
G71 Primary disorders of muscles	0.028	0.972	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.027	0.973	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.027	0.973	0.000
G25.0 Essential tremor	0.027	0.973	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.027	0.973	0.000
N20 Calculus of kidney and ureter	0.000	0.973	0.027
G03.9 Meningitis, unspecified	0.027	0.973	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.026	0.974	0.000
G22 Parkinsonism in diseases classified elsewhere	0.026	0.974	0.000
N20.0 Calculus of kidney	0.000	0.974	0.026
G23 Other degenerative diseases of basal ganglia	0.025	0.974	0.000
G25.3 Myoclonus	0.025	0.975	0.000
G80.1 Spastic diplegia	0.025	0.975	0.000
G24.5 Blepharospasm	0.025	0.975	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.025	0.975	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.024	0.976	0.000
G80.8 Other infantile cerebral palsy	0.024	0.976	0.000
G72.0 Drug-induced myopathy	0.024	0.976	0.000
G81.9 Hemiplegia, unspecified	0.023	0.977	0.000
G72.9 Myopathy, unspecified	0.023	0.977	0.000
G71.1 Myotonic disorders	0.023	0.977	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.023	0.977	0.000
G25.4 Drug-induced chorea	0.023	0.977	0.000
G21.9 Secondary Parkinsonism, unspecified	0.023	0.977	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.023	0.977	0.000
G21.0 Malignant neuroleptic syndrome	0.023	0.977	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.023	0.977	0.000
G70 Myasthenia gravis and other myoneural disorders	0.023	0.977	0.000
G24.0 Drug-induced dystonia	0.023	0.977	0.000
G25.2 Other specified forms of tremor	0.023	0.977	0.000
G81.0 Flaccid hemiplegia	0.022	0.978	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.022	0.978	0.000
G25.5 Other chorea	0.022	0.978	0.000
G24.1 Idiopathic familial dystonia	0.022	0.978	0.000
G25.1 Drug-induced tremor	0.022	0.978	0.000
G73.7 Myopathy other diseases classified elsewhere	0.021	0.978	0.000
G73.6 Myopathy in metabolic diseases	0.021	0.978	0.000
G73.5 Myopathy in endocrine diseases	0.021	0.978	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.021	0.978	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.021	0.978	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.021	0.978	0.000
G73.1 Eaton-Lambert syndrome	0.021	0.978	0.000
G80.4 Ataxic cerebral palsy	0.021	0.978	0.000
G80.3 Dyskinetic cerebral palsy	0.021	0.978	0.000
G21.8 Other secondary Parkinsonism	0.021	0.979	0.000
G21.4 Vascular parkinsonism	0.021	0.979	0.000
G21.3 Postencephalitic Parkinsonism	0.021	0.979	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.021	0.979	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.021	0.979	0.000
G24.4 Idiopathic orofacial dystonia	0.021	0.979	0.000
G24.2 Idiopathic nonfamilial dystonia	0.021	0.979	0.000
G04.0 Acute disseminated encephalitis	0.021	0.979	0.000
G80.0 Spastic cerebral palsy	0.021	0.979	0.000
G24.3 Spasmodic torticollis	0.021	0.979	0.000
G72.3 Periodic paralysis	0.021	0.979	0.000
G72.2 Myopathy due to other toxic agents	0.021	0.979	0.000
G72.1 Alcoholic myopathy	0.021	0.979	0.000
G72.8 Other specified myopathies	0.021	0.979	0.000
G03.8 Meningitis due to other specified causes	0.021	0.979	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.021	0.979	0.000
G03.1 Chronic meningitis	0.021	0.979	0.000
G03.0 Nonpyogenic meningitis	0.021	0.979	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.021	0.979	0.000
G81.1 Spastic hemiplegia	0.020	0.979	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.020	0.980	0.000
N20.9 Urinary calculus, unspecified	0.000	0.980	0.020
G71.9 Primary disorder of muscle, unspecified	0.020	0.980	0.000
G71.8 Other primary disorders of muscles	0.020	0.980	0.000
G71.2 Congenital myopathies	0.020	0.980	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.020	0.980	0.000
I49 Other cardiac arrhythmias	0.000	0.980	0.020
G80.2 Infantile hemiplegia	0.020	0.980	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.020	0.980	0.000
G24.8 Other dystonia	0.020	0.980	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.020	0.980	0.000
G04.1 Tropical spastic paraplegia	0.020	0.980	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.019	0.980	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.018	0.981	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.018	0.981	0.000
G23.3 Multiple system atrophy, cerebellar type	0.018	0.981	0.000
G23.2 Striatonigral degeneration	0.018	0.981	0.000
G23.0 Hallervorden-Spatz disease	0.018	0.981	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.982	0.018
G72.4 Inflammatory myopathy, not elsewhere classified	0.018	0.982	0.000
G24.9 Dystonia, unspecified	0.018	0.982	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.018	0.982	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.018	0.982	0.000
G00 Bacterial meningitis, not elsewhere classified	0.018	0.982	0.000
G70.8 Other specified myoneural disorders	0.018	0.982	0.000
G71.0 Muscular dystrophy	0.018	0.982	0.000
G70.9 Myoneural disorder, unspecified	0.017	0.983	0.000
G61 Inflammatory polyneuropathy	0.017	0.983	0.000
G70.2 Congenital and developmental myasthenia	0.016	0.983	0.000
G70.1 Toxic myoneural disorders	0.016	0.983	0.000
I49.1 Atrial premature depolarisation	0.000	0.984	0.016
I49.4 Other and unspecified premature depolarisation	0.000	0.984	0.016
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.016	0.984	0.000
G83 Other paralytic syndromes	0.016	0.984	0.000
G64 Other disorders of peripheral nervous system	0.016	0.984	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.015	0.985	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.015	0.985	0.000
I49.2 Junctional premature depolarisation	0.000	0.985	0.015
G61.8 Other inflammatory polyneuropathies	0.015	0.985	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.014	0.985	0.000
G02.1 Meningitis in mycoses	0.014	0.985	0.000
G00.2 Streptococcal meningitis	0.014	0.986	0.000
G06.2 Extradural and subdural abscess, unspecified	0.014	0.986	0.000
G80.9 Infantile cerebral palsy, unspecified	0.014	0.986	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.013	0.986	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.013	0.986	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.013	0.986	0.000
G00.8 Other bacterial meningitis	0.013	0.987	0.000
G00.3 Staphylococcal meningitis	0.013	0.987	0.000
G00.0 Haemophilus meningitis	0.013	0.987	0.000
G61.0 Guillain-Barre syndrome	0.012	0.988	0.000
G61.1 Serum neuropathy	0.012	0.988	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.012	0.988	0.000
G83.2 Monoplegia of upper limb	0.012	0.988	0.000
I49.5 Sick sinus syndrome	0.000	0.988	0.012
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.988	0.012
G83.5 Locked-in syndrome	0.012	0.988	0.000
G83.0 Diplegia of upper limbs	0.012	0.988	0.000
G83.3 Monoplegia, unspecified	0.012	0.988	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.012	0.988	0.000
G00.1 Pneumococcal meningitis	0.011	0.989	0.000
G83.1 Monoplegia of lower limb	0.011	0.989	0.000
G06.1 Intraspinal abscess and granuloma	0.011	0.989	0.000
G60 Hereditary and idiopathic neuropathy	0.010	0.990	0.000
G06.0 Intracranial abscess and granuloma	0.010	0.990	0.000
G36 Other acute disseminated demyelination	0.010	0.990	0.000
G83.9 Paralytic syndrome, unspecified	0.010	0.990	0.000
G20 Parkinson's disease	0.010	0.990	0.000
G62 Other polyneuropathies	0.010	0.990	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.009	0.990	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.009	0.991	0.001
G83.4 Cauda equina syndrome	0.009	0.991	0.000
G37 Other demyelinating diseases of central nervous system	0.009	0.991	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.991	0.009
G83.8 Other specified paralytic syndromes	0.008	0.991	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.991	0.009
G63.8 Polyneuropathy in other diseases classified elsewhere	0.008	0.991	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.008	0.991	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.008	0.991	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.008	0.991	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.008	0.991	0.000
G63.1 Polyneuropathy in neoplastic disease	0.008	0.991	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.008	0.991	0.000
M77.9 Enthesopathy, unspecified	0.000	0.992	0.008
N20.1 Calculus of ureter	0.000	0.992	0.008
I49.9 Cardiac arrhythmia, unspecified	0.000	0.992	0.008
G37.8 Other specified demyelinating diseases of central nervous system	0.008	0.992	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.000	0.992	0.008
G62.8 Other specified polyneuropathies	0.008	0.992	0.000
G00.9 Bacterial meningitis, unspecified	0.007	0.992	0.001
E27.1 Primary adrenocortical insufficiency	0.000	0.992	0.008
M77.94 Enthesopathy, unspecified (Hand)	0.000	0.992	0.008
G70.0 Myasthenia gravis	0.008	0.992	0.000
G62.0 Drug-induced polyneuropathy	0.008	0.992	0.000
G60.3 Idiopathic progressive neuropathy	0.007	0.992	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.007	0.992	0.000
G60.1 Refsum's disease	0.007	0.992	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.993	0.007
G36.9 Acute disseminated demyelination, unspecified	0.007	0.993	0.000
G36.8 Other specified acute disseminated demyelination	0.007	0.993	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.007	0.993	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.007	0.993	0.000
G62.2 Polyneuropathy due to other toxic agents	0.007	0.993	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.007	0.993	0.000
G37.5 Concentric sclerosis [Balo]	0.007	0.993	0.000
G37.4 Subacute necrotising myelitis	0.007	0.993	0.000
G37.2 Central pontine myelinolysis	0.007	0.993	0.000
G37.1 Central demyelination of corpus callosum	0.007	0.993	0.000
G37.0 Diffuse sclerosis	0.007	0.993	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M77.96 Enthesopathy, unspecified (Lower leg)	0.000	0.993	0.007
M81.9 Osteoporosis, unspecified	0.000	0.993	0.007
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.993	0.007
M81.98 Osteoporosis, unspecified (Other)	0.000	0.994	0.006
M77.99 Enthesopathy, unspecified (Site unspecified)	0.000	0.994	0.006
M77.98 Enthesopathy, unspecified (Other)	0.000	0.994	0.006
M77.93 Enthesopathy, unspecified (Forearm)	0.000	0.994	0.006
M77.90 Enthesopathy, unspecified (Multiple sites)	0.000	0.994	0.006
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.994	0.006
G36.0 Neuromyelitis optica [Devic]	0.006	0.994	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.006	0.994	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.994	0.006
I49.0 Ventricular fibrillation and flutter	0.000	0.994	0.006
I21.4 Acute subendocardial myocardial infarction	0.006	0.994	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.994	0.006
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.994	0.006
F80.1 Expressive language disorder	0.006	0.994	0.000
C67.4 Posterior wall of bladder	0.005	0.994	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.995	0.005
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.995	0.005
C67.9 Bladder, unspecified	0.005	0.995	0.000
G62.1 Alcoholic polyneuropathy	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.000	0.995	0.005
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.995	0.005
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.995	0.005
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.995	0.005
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
C67 Malignant neoplasm of bladder	0.005	0.995	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.005	0.995	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.995	0.005
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.995	0.005
G60.0 Hereditary motor and sensory neuropathy	0.004	0.995	0.000
E78.5 Hyperlipidaemia, unspecified	0.005	0.995	0.000
I72 Other aneurysm	0.000	0.995	0.005
C67.8 Overlapping lesion of bladder	0.004	0.995	0.000
C67.0 Trigone of bladder	0.004	0.995	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.996	0.004
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
F80 Specific developmental disorders of speech and language	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
I95.1 Orthostatic hypotension	0.004	0.996	0.000
D37.1 Stomach	0.000	0.996	0.004
I21 Acute myocardial infarction	0.004	0.996	0.000
C67.1 Dome of bladder	0.004	0.996	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.996	0.004
Z80.3 Family history of malignant neoplasm of breast	0.000	0.996	0.004
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.004
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.996	0.000
C67.6 Ureteric orifice	0.004	0.996	0.000
I72.9 Aneurysm of unspecified site	0.000	0.996	0.004
C67.2 Lateral wall of bladder	0.004	0.996	0.000
I72.3 Aneurysm of iliac artery	0.000	0.996	0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.996	0.004
C67.7 Urachus	0.004	0.996	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.004	0.996	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.996	0.004
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.996	0.004
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
I72.1 Aneurysm of artery of upper extremity	0.000	0.996	0.004
Chapter V Mental and behavioural disorders	0.004	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.996	0.004
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
N64.4 Mastodynia	0.000	0.996	0.004
F80-F89 Disorders of psychological development	0.004	0.996	0.000
S40 Superficial injury of shoulder and upper arm	0.004	0.996	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.996	0.003
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.004	0.996	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.996	0.003
M84 Disorders of continuity of bone	0.000	0.997	0.003
F80.9 Developmental disorder of speech and language, unspecified	0.003	0.997	0.000
F80.8 Other developmental disorders of speech and language	0.003	0.997	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.003	0.997	0.000
F80.0 Specific speech articulation disorder	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.003	0.997	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.003	0.997	0.000
M81 Osteoporosis without pathological fracture	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
I72.2 Aneurysm of renal artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
G35 Multiple sclerosis	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
M84.0 Malunion of fracture	0.000	0.997	0.003
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
F80.2 Receptive language disorder	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
K72 Hepatic failure, not elsewhere classified	0.000	0.997	0.003
K59.3 Megacolon, not elsewhere classified	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
D86 Sarcoidosis	0.000	0.997	0.003
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.003	0.997	0.000
F89 Unspecified disorder of psychological development	0.003	0.997	0.000
F88 Other disorders of psychological development	0.003	0.997	0.000
F83 Mixed specific developmental disorders	0.003	0.997	0.000
F82 Specific developmental disorder of motor function	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.000	0.997	0.003
N20-N23 Urolithiasis	0.000	0.997	0.003
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
I72.0 Aneurysm of carotid artery	0.000	0.997	0.003
C67.3 Anterior wall of bladder	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
C67.5 Bladder neck	0.003	0.997	0.000
G59.0 Diabetic mononeuropathy	0.003	0.997	0.000
M77 Other enthesopathies	0.000	0.997	0.003
M84.08 Malunion of fracture (Other)	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.003
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.003
F70-F79 Mental retardation	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.997	0.003
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.003	0.997	0.000
M77.0 Medial epicondylitis	0.000	0.997	0.003
M81.6 Localised osteoporosis [Lequesne]	0.000	0.997	0.003
M81.5 Idiopathic osteoporosis	0.000	0.997	0.003
M81.1 Postoophorectomy osteoporosis	0.000	0.997	0.003
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
F84 Pervasive developmental disorders	0.002	0.997	0.000
M77.02 Medial epicondylitis (Upper arm)	0.000	0.997	0.003
C69.3 Choroid	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.000	0.997	0.003
Z03.1 Observation for suspected malignant neoplasm	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.000	0.997	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.997	0.002
M81.8 Other osteoporosis	0.000	0.997	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.000	0.997	0.002
M84.4 Pathological fracture, not elsewhere classified	0.000	0.997	0.002
M95.0 Acquired deformity of nose	0.003	0.997	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.002	0.998	0.000
F93 Emotional disorders with onset specific to childhood	0.002	0.998	0.000
F92 Mixed disorders of conduct and emotions	0.002	0.998	0.000
F91 Conduct disorders	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
U80.1 Methicillin resistant agent	0.000	0.998	0.002
F95 Tic disorders	0.002	0.998	0.000
F90 Hyperkinetic disorders	0.002	0.998	0.000
M77.4 Metatarsalgia	0.000	0.998	0.002
F99-F99 Unspecified mental disorder	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
R63.1 Polydipsia	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.998	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.998	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.998	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.998	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.998	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.998	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.998	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.998	0.002
N64.1 Fat necrosis of breast	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
I51.7 Cardiomegaly	0.000	0.998	0.002
M77.8 Other enthesopathies, not elsewhere classified	0.000	0.998	0.002
M77.2 Periarthritis of wrist	0.000	0.998	0.002
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
F78 Other mental retardation	0.002	0.998	0.000
F73 Profound mental retardation	0.002	0.998	0.000
F72 Severe mental retardation	0.002	0.998	0.000
F71 Moderate mental retardation	0.002	0.998	0.000
F70 Mild mental retardation	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.002
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.002
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.002
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.002
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.002
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations