TreeWAS – Variant ID: rs4129767

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S22.20 Fracture of sternum (closed)	0.081	0.919	0.000
S22.2 Fracture of sternum	0.079	0.921	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.079	0.921	0.000
S20-S29 Injuries to the thorax	0.073	0.927	0.000
S22.0 Fracture of thoracic vertebra	0.073	0.927	0.000
S27 Injury of other and unspecified intrathoracic organs	0.072	0.928	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.069	0.931	0.000
S27.1 Traumatic haemothorax	0.069	0.931	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.068	0.932	0.000
S29 Other and unspecified injuries of thorax	0.065	0.935	0.000
S22.3 Fracture of rib	0.062	0.938	0.000
S22.4 Multiple fractures of ribs	0.060	0.940	0.000
S27.3 Other injuries of lung	0.058	0.941	0.000
S22.1 Multiple fractures of thoracic spine	0.057	0.942	0.000
S24 Injury of nerves and spinal cord at thorax level	0.057	0.943	0.000
S22.21 Fracture of sternum (open)	0.057	0.943	0.000
S22.9 Fracture of bony thorax, part unspecified	0.057	0.943	0.000
S22.8 Fracture of other parts of bony thorax	0.057	0.943	0.000
S29.9 Unspecified injury of thorax	0.054	0.946	0.000
S27.8 Injury of other specified intrathoracic organs	0.054	0.946	0.000
S27.2 Traumatic heamopneumothorax	0.054	0.946	0.000
S29.8 Other specified injuries of thorax	0.054	0.946	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.053	0.947	0.000
S26 Injury of heart	0.053	0.947	0.000
S25 Injury of blood vessels of thorax	0.053	0.947	0.000
S22.01 Fracture of thoracic vertebra (open)	0.053	0.947	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.052	0.948	0.000
S27.9 Injury of unspecified intrathoracic organ	0.052	0.948	0.000
S27.7 Multiple injuries of intrathoracic organs	0.052	0.948	0.000
S27.6 Injury of pleura	0.052	0.948	0.000
S27.5 Injury of thoracic trachea	0.052	0.948	0.000
S27.4 Injury of bronchus	0.052	0.948	0.000
S20 Superficial injury of thorax	0.051	0.949	0.000
S29.0 Injury of muscle and tendon at thorax level	0.050	0.950	0.000
S22.30 Fracture of rib (closed)	0.050	0.950	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.050	0.950	0.000
S27.0 Traumatic pneumothorax	0.050	0.950	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.049	0.951	0.000
S21 Open wound of thorax	0.048	0.952	0.000
S29.7 Multiple injuries of thorax	0.047	0.953	0.000
S22.40 Multiple fractures of ribs (closed)	0.047	0.953	0.000
S22.5 Flail chest	0.046	0.954	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.045	0.955	0.000
S22.31 Fracture of rib (open)	0.045	0.955	0.000
S20.3 Other superficial injuries of front wall of thorax	0.043	0.957	0.000
S22.41 Multiple fractures of ribs (open)	0.043	0.957	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.042	0.958	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.042	0.958	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.041	0.958	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.041	0.959	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.041	0.959	0.000
S24.6 Injury of unspecified nerve of thorax	0.041	0.959	0.000
S24.5 Injury of other nerves of thorax	0.041	0.959	0.000
S24.4 Injury of thoracic sympathetic nerves	0.041	0.959	0.000
S24.3 Injury of peripheral nerves of thorax	0.041	0.959	0.000
S24.2 Injury of nerve root of thoracic spine	0.041	0.959	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.041	0.959	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.041	0.959	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.041	0.959	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.041	0.959	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.041	0.959	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.041	0.959	0.000
S20.4 Other superficial injuries of back wall of thorax	0.039	0.961	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.039	0.961	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.039	0.961	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.038	0.962	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.038	0.962	0.000
S25.8 Injury of other blood vessels of thorax	0.038	0.962	0.000
S25.7 Injury of multiple blood vessels of thorax	0.038	0.962	0.000
S25.5 Injury of intercostal blood vessels	0.038	0.962	0.000
S25.4 Injury of pulmonary blood vessels	0.038	0.962	0.000
S25.3 Injury of innominate or subclavian vein	0.038	0.962	0.000
S25.2 Injury of superior vena cava	0.038	0.962	0.000
S25.1 Injury of innominate or subclavian artery	0.038	0.962	0.000
S25.0 Injury of thoracic aorta	0.038	0.962	0.000
S26.9 Injury of heart, unspecified	0.038	0.962	0.000
S26.8 Other injuries of heart	0.038	0.962	0.000
S26.0 Injury of heart with haemopericardium	0.038	0.962	0.000
S28.1 Traumatic amputation of part of thorax	0.038	0.962	0.000
S28.0 Crushed chest	0.038	0.962	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.038	0.962	0.000
S23.3 Sprain and strain of thoracic spine	0.038	0.962	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.038	0.962	0.000
S23.1 Dislocation of thoracic vertebra	0.038	0.962	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.038	0.962	0.000
S23.4 Sprain and strain of ribs and sternum	0.037	0.963	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.037	0.963	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.037	0.963	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.037	0.963	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.037	0.963	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.037	0.963	0.000
S21.1 Open wound of front wall of thorax	0.037	0.963	0.000
S20.7 Multiple superficial injuries of thorax	0.036	0.963	0.000
Z34.8 Supervision of other normal pregnancy	0.036	0.964	0.000
S21.0 Open wound of breast	0.036	0.964	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.965	0.035
S21.8 Open wound of other parts of thorax	0.035	0.965	0.000
S21.7 Multiple open wounds of thoracic wall	0.035	0.965	0.000
S22.51 Flail chest (open)	0.033	0.967	0.000
S20.1 Other and unspecified superficial injuries of breast	0.031	0.969	0.000
S21.2 Open wound of back wall of thorax	0.031	0.969	0.000
S20.0 Contusion of breast	0.030	0.970	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.030	0.970	0.000
S21.9 Open wound of thorax, part unspecified	0.030	0.970	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.027	0.972	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.027	0.972	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.027	0.972	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.027	0.972	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.027	0.972	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.027	0.972	0.000
S20.2 Contusion of thorax	0.026	0.974	0.000
S22.50 Flail chest (closed)	0.022	0.977	0.000
H80.9 Otosclerosis, unspecified	0.013	0.987	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.011	0.989	0.000
I35.0 Aortic (valve) stenosis	0.011	0.989	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.991	0.009
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.008	0.992	0.000
I35 Nonrheumatic aortic valve disorders	0.008	0.992	0.000
D32.0 Cerebral meninges	0.008	0.992	0.000
D69.4 Other primary thrombocytopenia	0.000	0.992	0.008
D69.5 Secondary thrombocytopenia	0.000	0.992	0.008
M20.2 Hallux rigidus	0.000	0.992	0.008
D69.1 Qualitative platelet defects	0.000	0.993	0.007
J15.1 Pneumonia due to Pseudomonas	0.000	0.993	0.007
D69.2 Other nonthrombocytopenic purpura	0.000	0.994	0.006
D69.8 Other specified haemorrhagic conditions	0.000	0.994	0.006
D69.6 Thrombocytopenia, unspecified	0.000	0.994	0.006
C45.0 Mesothelioma of pleura	0.000	0.994	0.006
H73.8 Other specified disorders of tympanic membrane	0.000	0.994	0.006
D69.0 Allergic purpura	0.000	0.994	0.006
D32 Benign neoplasm of meninges	0.006	0.994	0.000
D32.9 Meninges, unspecified	0.006	0.994	0.000
F45.8 Other somatoform disorders	0.000	0.994	0.006
I86.1 Scrotal varices	0.000	0.994	0.006
S02.60 Fracture of mandible (closed)	0.005	0.995	0.000
H80 Otosclerosis	0.005	0.995	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.995	0.005
I35.1 Aortic (valve) insufficiency	0.005	0.995	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.995	0.005
D69.9 Haemorrhagic condition, unspecified	0.000	0.995	0.005
J15.9 Bacterial pneumonia, unspecified	0.000	0.995	0.005
S92.20 Fracture of other tarsal bone(s) (closed)	0.005	0.995	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.995	0.005
Z34 Supervision of normal pregnancy	0.005	0.995	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.995	0.005
S92.41 Fracture of great toe (open)	0.004	0.995	0.000
D32.1 Spinal meninges	0.004	0.996	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.996	0.004
T36.0 Penicillins	0.004	0.996	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
H80.8 Other otosclerosis	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.004	0.996	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.004	0.996	0.000
J15.3 Pneumonia due to streptococcus, group B	0.000	0.996	0.004
C45 Mesothelioma	0.000	0.996	0.004
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.996	0.004
O00.1 Tubal pregnancy	0.000	0.996	0.004
T40.4 Other synthetic narcotics	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.996	0.004
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.996	0.004
I35.9 Aortic valve disorder, unspecified	0.003	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.996	0.004
K82.8 Other specified diseases of gallbladder	0.000	0.997	0.003
T36.3 Macrolides	0.003	0.997	0.000
J15.5 Pneumonia due to Escherichia coli	0.000	0.997	0.003
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
E87.7 Fluid overload	0.000	0.997	0.003
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.997	0.003
V18 Pedal cyclist injured in noncollision transport accident	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
I35.8 Other aortic valve disorders	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
J15.8 Other bacterial pneumonia	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.003	0.997	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
T40.5 Cocaine	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
D26.0 Cervix uteri	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.000	0.997	0.003
V18.3 Person injured while boarding or alighting	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
V18.9 Unspecified pedal cyclist injured in traffic accident	0.003	0.997	0.000
V18.4 Driver injured in traffic accident	0.003	0.997	0.000
V18.5 Passenger injured in traffic accident	0.003	0.997	0.000
I86 Varicose veins of other sites	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
T75.4 Effects of electric current	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.997	0.000
H73.0 Acute myringitis	0.000	0.997	0.002
T47.6 Antidiarrhoeal drugs	0.002	0.997	0.000
H73.1 Chronic myringitis	0.000	0.997	0.002
T47.2 Stimulant laxatives	0.002	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
S02.6 Fracture of mandible	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
H05.0 Acute inflammation of orbit	0.000	0.998	0.002
T45.5 Anticoagulants	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
I86.3 Vulval varices	0.000	0.998	0.002
K22.0 Achalasia of cardia	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
F45.0 Somatisation disorder	0.000	0.998	0.002
V17.4 Driver injured in traffic accident	0.002	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
I86.2 Pelvic varices	0.000	0.998	0.002
X68.9 Unspecified place	0.002	0.998	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.002	0.998	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.002	0.998	0.000
I86.0 Sublingual varices	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
V17.0 Driver injured in nontraffic accident	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T63.4 Venom of other arthropods	0.002	0.998	0.000
O00 Ectopic pregnancy	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.998	0.002
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.998	0.002
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.998	0.002
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.998	0.002
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.998	0.002
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.998	0.002
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
D33.3 Cranial nerves	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.998	0.002
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
V17.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
N04.9 Unspecified	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.998	0.002
O00.9 Ectopic pregnancy, unspecified	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
V17.9 Unspecified pedal cyclist injured in traffic accident	0.002	0.998	0.000
V17.5 Passenger injured in traffic accident	0.002	0.998	0.000
V17.3 Person injured while boarding or alighting	0.002	0.998	0.000
V17.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
H47.2 Optic atrophy	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
O00.8 Other ectopic pregnancy	0.000	0.998	0.002
O00.2 Ovarian pregnancy	0.000	0.998	0.002
O00.0 Abdominal pregnancy	0.000	0.998	0.002
D33.4 Spinal cord	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
N36.0 Urethral fistula	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.998	0.002
T42.1 Iminostilbenes	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
V10-V19 Pedal cyclist injured in transport accident	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
C18.6 Descending colon	0.000	0.998	0.002
D33.2 Brain, unspecified	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
S82.86 Maisonneuve's fracture	0.001	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.998	0.000
H18.7 Other corneal deformities	0.001	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T92.1 Sequelae of fracture of arm	0.000	0.998	0.002
F45.3 Somatoform autonomic dysfunction	0.000	0.998	0.001
K50.8 Other Crohn's disease	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.000	0.998	0.002
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
K52.3 Indeterminate colitis	0.001	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.998	0.001
M71.34 Other bursal cyst (Hand)	0.000	0.998	0.001
B00.4 Herpesviral encephalitis	0.001	0.998	0.000
J32.4 Chronic pansinusitis	0.001	0.998	0.000
D33.0 Brain, supratentorial	0.001	0.999	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
J31.0 Chronic rhinitis	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.999	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.999	0.000
V48.0 Driver injured in nontraffic accident	0.000	0.999	0.001
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.001	0.999	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.001	0.999	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.001	0.999	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.001	0.999	0.000
T75 Effects of other external causes	0.001	0.999	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.999	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.001	0.999	0.000
D33.9 Central nervous system, unspecified	0.001	0.999	0.000
D33.7 Other specified parts of central nervous system	0.001	0.999	0.000
D33.1 Brain, infratentorial	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.999	0.000
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
M25.53 Pain in joint (Forearm)	0.000	0.999	0.001
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.999	0.000
N36.8 Other specified disorders of urethra	0.001	0.999	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations