TreeWAS – Variant ID: rs4148689

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S92.00 Fracture of calcaneus (closed)	0.060	0.940	0.000
S92 Fracture of foot, except ankle	0.060	0.940	0.000
S92.0 Fracture of calcaneus	0.060	0.940	0.000
S92.3 Fracture of metatarsal bone	0.055	0.945	0.000
S92.30 Fracture of metatarsal bone (closed)	0.052	0.948	0.000
S92.1 Fracture of talus	0.050	0.950	0.000
S90-S99 Injuries to the ankle and foot	0.049	0.951	0.000
S92.2 Fracture of other tarsal bone(s)	0.048	0.952	0.000
S92.7 Multiple fractures of foot	0.047	0.952	0.000
S92.5 Fracture of other toe	0.045	0.955	0.000
S90 Superficial injury of ankle and foot	0.044	0.956	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.043	0.957	0.000
S92.9 Fracture of foot, unspecified	0.043	0.957	0.000
S92.01 Fracture of calcaneus (open)	0.043	0.957	0.000
S92.4 Fracture of great toe	0.043	0.957	0.000
S92.10 Fracture of talus (closed)	0.042	0.958	0.000
S99 Other and unspecified injuries of ankle and foot	0.041	0.959	0.000
S90.8 Other superficial injuries of ankle and foot	0.041	0.959	0.000
S92.31 Fracture of metatarsal bone (open)	0.040	0.960	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.039	0.961	0.000
S92.70 Multiple fractures of foot (closed)	0.038	0.961	0.000
S97 Crushing injury of ankle and foot	0.037	0.963	0.000
S92.50 Fracture of other toe (closed)	0.036	0.964	0.000
S93.1 Dislocation of toe(s)	0.036	0.964	0.000
S99.9 Unspecified injury of ankle and foot	0.036	0.964	0.000
S92.11 Fracture of talus (open)	0.036	0.964	0.000
S93.0 Dislocation of ankle joint	0.036	0.964	0.000
S98 Traumatic amputation of ankle and foot	0.035	0.965	0.000
S95 Injury of blood vessels at ankle and foot level	0.035	0.965	0.000
S94 Injury of nerves at ankle and foot level	0.035	0.965	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.034	0.965	0.000
S92.71 Multiple fractures of foot (open)	0.034	0.966	0.000
S90.0 Contusion of ankle	0.033	0.967	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.033	0.967	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.032	0.967	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.032	0.968	0.000
S90.2 Contusion of toe(s) with damage to nail	0.032	0.968	0.000
S90.1 Contusion of toe(s) without damage to nail	0.032	0.968	0.000
S92.41 Fracture of great toe (open)	0.031	0.969	0.000
S93.4 Sprain and strain of ankle	0.031	0.969	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.031	0.969	0.000
S93.5 Sprain and strain of toe(s)	0.031	0.969	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.031	0.969	0.000
S92.91 Fracture of foot, unspecified (open)	0.031	0.969	0.000
S92.90 Fracture of foot, unspecified (closed)	0.031	0.969	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.031	0.969	0.000
S90.3 Contusion of other and unspecified parts of foot	0.030	0.969	0.000
S92.40 Fracture of great toe (closed)	0.030	0.970	0.000
S99.7 Multiple injuries of ankle and foot	0.030	0.970	0.000
S99.8 Other specified injuries of ankle and foot	0.029	0.971	0.000
S92.51 Fracture of other toe (open)	0.029	0.971	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.028	0.972	0.000
S97.1 Crushing injury of toe(s)	0.026	0.973	0.000
S97.0 Crushing injury of ankle	0.026	0.973	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.025	0.975	0.000
S94.8 Injury of other nerves at ankle and foot level	0.025	0.975	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.025	0.975	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.025	0.975	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.025	0.975	0.000
S94.1 Injury of medial plantar nerve	0.025	0.975	0.000
S94.0 Injury of lateral plantar nerve	0.025	0.975	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.025	0.975	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.025	0.975	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.025	0.975	0.000
S95.2 Injury of dorsal vein of foot	0.025	0.975	0.000
S95.1 Injury of plantar artery of foot	0.025	0.975	0.000
S95.0 Injury of dorsal artery of foot	0.025	0.975	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.025	0.975	0.000
S98.3 Traumatic amputation of other parts of foot	0.025	0.975	0.000
S98.2 Traumatic amputation of two or more toes	0.025	0.975	0.000
S98.1 Traumatic amputation of one toe	0.025	0.975	0.000
S98.0 Traumatic amputation of foot at ankle level	0.025	0.975	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.025	0.975	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.024	0.976	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.976	0.024
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.024	0.976	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.024	0.976	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.024	0.976	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.024	0.976	0.000
S93.40 Sprain of unspecified ligament of ankle	0.023	0.977	0.000
S91 Open wound of ankle and foot	0.022	0.977	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.021	0.978	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.982	0.018
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.982	0.018
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.983	0.017
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.983	0.017
S91.7 Multiple open wounds of ankle and foot	0.016	0.984	0.000
S91.2 Open wound of toe(s) with damage to nail	0.016	0.984	0.000
S91.3 Open wound of other parts of foot	0.015	0.984	0.000
S91.0 Open wound of ankle	0.014	0.986	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.987	0.013
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.987	0.013
S91.1 Open wound of toe(s) without damage to nail	0.009	0.990	0.001
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.990	0.010
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.991	0.009
L72.0 Epidermal cyst	0.009	0.991	0.000
Z40 Prophylactic surgery	0.009	0.991	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.992	0.008
S42.2 Fracture of upper end of humerus	0.000	0.993	0.007
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.007	0.993	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.993	0.007
S42 Fracture of shoulder and upper arm	0.000	0.993	0.007
S42.0 Fracture of clavicle	0.000	0.993	0.007
K50.1 Crohn's disease of large intestine	0.000	0.993	0.007
S42.30 Fracture of shaft of humerus (closed)	0.000	0.993	0.007
S42.3 Fracture of shaft of humerus	0.000	0.993	0.007
Z40.9 Prophylactic surgery, unspecified	0.006	0.994	0.000
J81 Pulmonary oedema	0.006	0.994	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.994	0.006
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.006	0.994	0.000
S42.4 Fracture of lower end of humerus	0.000	0.994	0.006
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.994	0.006
S42.21 Fracture of upper end of humerus (open)	0.000	0.994	0.005
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.995	0.005
Z40.8 Other prophylactic surgery	0.005	0.995	0.000
S42.01 Fracture of clavicle (open)	0.000	0.995	0.005
K50 Crohn's disease [regional enteritis]	0.000	0.995	0.005
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.005	0.995	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.995	0.005
S42.1 Fracture of scapula	0.000	0.995	0.005
Z08 Follow-up examination after treatment for malignant neoplasm	0.005	0.995	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.000	0.995	0.005
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
S42.40 Fracture of lower end of humerus (closed)	0.000	0.995	0.005
S42.41 Fracture of lower end of humerus (open)	0.000	0.995	0.005
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.995	0.005
N41.1 Chronic prostatitis	0.005	0.995	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.005	0.995	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.996	0.004
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.996	0.004
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.996	0.004
G63.2 Diabetic polyneuropathy	0.004	0.996	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.004	0.996	0.000
N99.0 Postprocedural renal failure	0.004	0.996	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.004	0.996	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.996	0.004
S42.11 Fracture of scapula (open)	0.000	0.996	0.004
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
Z54.0 Convalescence following surgery	0.004	0.996	0.000
N99.1 Postprocedural urethral stricture	0.004	0.996	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.996	0.003
S52.60 Fracture of lower end of both ulna and radius (closed)	0.004	0.996	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.003	0.996	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.000	0.996	0.003
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.003	0.996	0.000
K62.5 Haemorrhage of anus and rectum	0.003	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
I84.7 Unspecified thrombosed haemorrhoids	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.997	0.003
N99.5 Malfunction of external stoma of urinary tract	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.997	0.003
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
I31.3 Pericardial effusion (noninflammatory)	0.000	0.997	0.003
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
K01.1 Impacted teeth	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
Z54.8 Convalescence following other treatment	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.000	0.998	0.002
Z54 Convalescence	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
N18.0 End-stage renal disease	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
N41 Inflammatory diseases of prostate	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
N41.8 Other inflammatory diseases of prostate	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
N99-N99 Other disorders of the genitourinary system	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
Z54.9 Convalescence following unspecified treatment	0.002	0.998	0.000
Z54.7 Convalescence following combined treatment	0.002	0.998	0.000
Z54.3 Convalescence following psychotherapy	0.002	0.998	0.000
Z54.2 Convalescence following chemotherapy	0.002	0.998	0.000
Z54.1 Convalescence following radiotherapy	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
N41.3 Prostatocystitis	0.002	0.998	0.000
N41.2 Abscess of prostate	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
U88 Agent resistant to multiple antibiotics	0.002	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.000	0.998	0.001
Z54.4 Convalescence following treatment of fracture	0.001	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.001
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.998	0.002
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.001
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.001
C71.7 Brain stem	0.000	0.998	0.001
C71.6 Cerebellum	0.000	0.998	0.001
C71.5 Cerebral ventricle	0.000	0.998	0.001
N42.8 Other specified disorders of prostate	0.001	0.999	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.001	0.999	0.000
C34.0 Main bronchus	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.999	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.999	0.001
K82.9 Disease of gallbladder, unspecified	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.999	0.001
R86.0 Abnormal level of enzymes	0.001	0.999	0.000
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
N41.9 Inflammatory disease of prostate, unspecified	0.001	0.999	0.000
R86.7 Abnormal histological findings	0.001	0.999	0.000
R86 Abnormal findings in specimens from male genital organs	0.001	0.999	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.001	0.999	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.999	0.001
R25.1 Tremor, unspecified	0.001	0.999	0.000
R86.6 Abnormal cytological findings	0.001	0.999	0.000
R18 Ascites	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
K01.0 Embedded teeth	0.000	0.999	0.001
K82.4 Cholesterolosis of gallbladder	0.000	0.999	0.001
N41.0 Acute prostatitis	0.001	0.999	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
J32.8 Other chronic sinusitis	0.001	0.999	0.000
L65.9 Nonscarring hair loss, unspecified	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
H81.1 Benign paroxysmal vertigo	0.000	0.999	0.001
N70 Salpingitis and oophoritis	0.001	0.999	0.000
I95.2 Hypotension due to drugs	0.000	0.999	0.001
J33.8 Other polyp of sinus	0.001	0.999	0.000
R89.5 Abnormal microbiological findings	0.001	0.999	0.000
Z63.4 Disappearance and death of family member	0.000	0.999	0.001
R86.8 Other abnormal findings	0.001	0.999	0.000
Z49.2 Other dialysis	0.000	0.999	0.001
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.999	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.999	0.001
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.999	0.001
R44.1 Visual hallucinations	0.001	0.999	0.000
R86.9 Unspecified abnormal finding	0.001	0.999	0.000
R86.5 Abnormal microbiological findings	0.001	0.999	0.000
R86.4 Abnormal immunological findings	0.001	0.999	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R86.1 Abnormal level of hormones	0.001	0.999	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.000	0.999	0.001
I95.0 Idiopathic hypotension	0.000	0.999	0.001
K01 Embedded and impacted teeth	0.000	0.999	0.001
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.001	0.999	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.999	0.001
M46.2 Osteomyelitis of vertebra	0.001	0.999	0.000
W21.9 Unspecified place	0.001	0.999	0.000
K82 Other diseases of gallbladder	0.000	0.999	0.001
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.999	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.001	0.999	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.999	0.001
D68.0 Von Willebrand's disease	0.000	0.999	0.001
R84.9 Unspecified abnormal finding	0.001	0.999	0.000
R84.8 Other abnormal findings	0.001	0.999	0.000
R84.7 Abnormal histological findings	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.001	0.999	0.000
R84.4 Abnormal immunological findings	0.001	0.999	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R84.1 Abnormal level of hormones	0.001	0.999	0.000
R84.0 Abnormal level of enzymes	0.001	0.999	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.001	0.999	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.999	0.001
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.001	0.999	0.000
C71.2 Temporal lobe	0.000	0.999	0.001
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
N60.9 Benign mammary dysplasia, unspecified	0.001	0.999	0.000
N70.0 Acute salpingitis and oophoritis	0.001	0.999	0.000
R89.7 Abnormal histological findings	0.001	0.999	0.000
Z49 Care involving dialysis	0.000	0.999	0.001
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.001	0.999	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.001	0.999	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.001	0.999	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.001	0.999	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.001	0.999	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.001	0.999	0.000
J94.2 Haemothorax	0.000	0.999	0.001
K82.0 Obstruction of gallbladder	0.000	0.999	0.001
N60.3 Fibrosclerosis of breast	0.001	0.999	0.000
O46.8 Other antepartum haemorrhage	0.000	0.999	0.001
Z96.7 Presence of other bone and tendon implants	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
G93.6 Cerebral oedema	0.001	0.999	0.000
K82.3 Fistula of gallbladder	0.000	0.999	0.001
R89.9 Unspecified abnormal finding	0.001	0.999	0.000
R89.8 Other abnormal findings	0.001	0.999	0.000
R89.6 Abnormal cytological findings	0.001	0.999	0.000
R89.4 Abnormal immunological findings	0.001	0.999	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R89.1 Abnormal level of hormones	0.001	0.999	0.000
R89.0 Abnormal level of enzymes	0.001	0.999	0.000
D68 Other coagulation defects	0.000	0.999	0.001
I31 Other diseases of pericardium	0.000	0.999	0.001
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.999	0.001
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
E06.9 Thyroiditis, unspecified	0.000	0.999	0.001
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
J95.9 Postprocedural respiratory disorder, unspecified	0.001	0.999	0.000
K10.8 Other specified diseases of jaws	0.001	0.999	0.000
M40.2 Other and unspecified kyphosis	0.001	0.999	0.000
U89.9 Agent resistant to unspecified antibiotic	0.001	0.999	0.000
M46 Other inflammatory spondylopathies	0.001	0.999	0.000
C80.9 Malignant neoplasm, unspecified	0.001	0.999	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.999	0.001
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.999	0.001
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.999	0.000
I31.8 Other specified diseases of pericardium	0.000	0.999	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.999	0.001
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.999	0.001
M46.1 Sacro-iliitis, not elsewhere classified	0.001	0.999	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.999	0.001
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.001	0.999	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.001	0.999	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.001	0.999	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.001	0.999	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.001	0.999	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.999	0.000
I20.1 Angina pectoris with documented spasm	0.001	0.999	0.000
K82.2 Perforation of gallbladder	0.000	0.999	0.001
M46.8 Other specified inflammatory spondylopathies	0.001	0.999	0.000
M46.5 Other infective spondylopathies	0.001	0.999	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.001	0.999	0.000
M46.0 Spinal enthesopathy	0.001	0.999	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.999	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.001	0.999	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.001	0.999	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.001	0.999	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.001	0.999	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.001	0.999	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.001	0.999	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.001	0.999	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.001	0.999	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.001	0.999	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.001	0.999	0.000
R25.2 Cramp and spasm	0.001	0.999	0.000
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
V89.9 Person injured in unspecified vehicle accident	0.001	0.999	0.000
U89 Agent resistant to other and unspecified antibiotics	0.001	0.999	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.001	0.999	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.001	0.999	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.001	0.999	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.001	0.999	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.001	0.999	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.001	0.999	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.001	0.999	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.001	0.999	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.001	0.999	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.001	0.999	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.001	0.999	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.001	0.999	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.001	0.999	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.001	0.999	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.001	0.999	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.001	0.999	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.001	0.999	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.001	0.999	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.001	0.999	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.001	0.999	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.001	0.999	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.001	0.999	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.001	0.999	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.001	0.999	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.001	0.999	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.001	0.999	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
M94.26 Chondromalacia (Lower leg)	0.001	0.999	0.000
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
K82.1 Hydrops of gallbladder	0.000	0.999	0.001
N60.2 Fibroadenosis of breast	0.001	0.999	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.999	0.001
J95 Postprocedural respiratory disorders, not elsewhere classified	0.001	0.999	0.000
U84 Resistance to other antimicrobial drugs	0.001	0.999	0.000
U83 Resistance to other antibiotics	0.001	0.999	0.000
U82 Resistance to betalactam antibiotics	0.001	0.999	0.000
U85 Resistance to antineoplastic drugs	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
H53.0 Amblyopia ex anopsia	0.000	0.999	0.001
I63.9 Cerebral infarction, unspecified	0.001	0.999	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.999	0.001
M46.4 Discitis, unspecified	0.001	0.999	0.000
R06.1 Stridor	0.000	0.999	0.001
U82.9 Resistance to betalactam antibiotics, unspecified	0.001	0.999	0.000
U82.8 Resistance to other betalactam antibiotics	0.001	0.999	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.001	0.999	0.000
U82.1 Resistance to methicillin	0.001	0.999	0.000
U82.0 Resistance to penicillin	0.001	0.999	0.000
U83.9 Resistance to unspecified antibiotic	0.001	0.999	0.000
U83.8 Resistance to other single specified antibiotic	0.001	0.999	0.000
U83.7 Resistance to multiple antibiotics	0.001	0.999	0.000
U83.2 Resistance to quinolones	0.001	0.999	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.001	0.999	0.000
U83.0 Resistance to vancomycin	0.001	0.999	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.001	0.999	0.000
U84.8 Resistance to other specified antimicrobial drug	0.001	0.999	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.001	0.999	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.001	0.999	0.000
U84.2 Resistance to antiviral drug(s)	0.001	0.999	0.000
U84.1 Resistance to antifungal drug(s)	0.001	0.999	0.000
U84.0 Resistance to antiparasitic drug(s)	0.001	0.999	0.000
Z43.3 Attention to colostomy	0.000	0.999	0.001
R25 Abnormal involuntary movements	0.001	0.999	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.999	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.001	0.999	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M46.42 Discitis, unspecified (Cervical region)	0.001	0.999	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
E10.4 With neurological complications	0.001	0.999	0.000
J95.5 Postprocedural subglottic stenosis	0.001	0.999	0.000
J95.4 Mendelson's syndrome	0.001	0.999	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.001	0.999	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.001	0.999	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.001	0.999	0.000
M89.3 Hypertrophy of bone	0.001	0.999	0.000
R25.0 Abnormal head movements	0.001	0.999	0.000
R85.5 Abnormal microbiological findings	0.001	0.999	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.999	0.001
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.999	0.001
G93 Other disorders of brain	0.001	0.999	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations