TreeWAS – Variant ID: rs4148808

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.000	1.000
K80 Cholelithiasis	0.000	0.000	1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.000	1.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.000	1.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.000	1.000
K81 Cholecystitis	0.000	0.000	1.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.001	0.999
K83 Other diseases of biliary tract	0.000	0.004	0.996
K81.9 Cholecystitis, unspecified	0.000	0.007	0.993
K83.8 Other specified diseases of biliary tract	0.000	0.010	0.990
K86 Other diseases of pancreas	0.000	0.013	0.987
K81.0 Acute cholecystitis	0.000	0.041	0.959
K81.1 Chronic cholecystitis	0.000	0.071	0.929
K86.1 Other chronic pancreatitis	0.000	0.071	0.929
K86.2 Cyst of pancreas	0.000	0.079	0.921
K85 Acute pancreatitis	0.000	0.119	0.881
K83.0 Cholangitis	0.000	0.142	0.858
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.162	0.838
K80.4 Calculus of bile duct with cholecystitis	0.000	0.182	0.818
K83.9 Disease of biliary tract, unspecified	0.000	0.192	0.808
K85.1 Biliary acute pancreatitis	0.000	0.196	0.804
K83.1 Obstruction of bile duct	0.000	0.207	0.793
K82 Other diseases of gallbladder	0.000	0.231	0.769
K81.8 Other cholecystitis	0.000	0.241	0.758
K86.3 Pseudocyst of pancreas	0.000	0.242	0.757
K80.3 Calculus of bile duct with cholangitis	0.000	0.283	0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.283	0.717
K83.5 Biliary cyst	0.000	0.286	0.714
K83.3 Fistula of bile duct	0.000	0.286	0.714
K83.2 Perforation of bile duct	0.000	0.286	0.714
K86.9 Disease of pancreas, unspecified	0.000	0.291	0.709
K80.8 Other cholelithiasis	0.000	0.317	0.683
K85.2 Alcohol-induced acute pancreatitis	0.000	0.335	0.665
K82.2 Perforation of gallbladder	0.000	0.359	0.641
K85.3 Drug-induced acute pancreatitis	0.000	0.368	0.631
K85.0 Idiopathic acute pancreatitis	0.000	0.368	0.631
K85.9 Acute pancreatitis, unspecified	0.000	0.390	0.610
K82.8 Other specified diseases of gallbladder	0.000	0.401	0.599
K85.8 Other acute pancreatitis	0.000	0.415	0.585
K82.9 Disease of gallbladder, unspecified	0.000	0.423	0.577
K82.3 Fistula of gallbladder	0.000	0.449	0.551
K83.4 Spasm of sphincter of Oddi	0.000	0.450	0.549
K86.8 Other specified diseases of pancreas	0.000	0.455	0.545
K82.0 Obstruction of gallbladder	0.000	0.463	0.537
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.486	0.514
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.486	0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.486	0.514
K82.4 Cholesterolosis of gallbladder	0.000	0.488	0.512
K82.1 Hydrops of gallbladder	0.000	0.557	0.443
K70 Alcoholic liver disease	0.000	0.958	0.042
K70-K77 Diseases of liver	0.000	0.959	0.041
K70.3 Alcoholic cirrhosis of liver	0.000	0.959	0.041
D86.9 Sarcoidosis, unspecified	0.000	0.960	0.040
D86.0 Sarcoidosis of lung	0.000	0.960	0.040
K72 Hepatic failure, not elsewhere classified	0.000	0.961	0.039
D86 Sarcoidosis	0.000	0.961	0.039
K72.0 Acute and subacute hepatic failure	0.000	0.963	0.037
K70.0 Alcoholic fatty liver	0.000	0.964	0.036
K74 Fibrosis and cirrhosis of liver	0.000	0.964	0.036
Chapter XI Diseases of the digestive system	0.000	0.964	0.036
K90-K93 Other diseases of the digestive system	0.000	0.966	0.034
K70.4 Alcoholic hepatic failure	0.000	0.967	0.033
K70.9 Alcoholic liver disease, unspecified	0.000	0.968	0.032
K72.9 Hepatic failure, unspecified	0.000	0.968	0.032
K70.1 Alcoholic hepatitis	0.000	0.968	0.032
D86.8 Sarcoidosis of other and combined sites	0.000	0.969	0.031
K74.6 Other and unspecified cirrhosis of liver	0.000	0.969	0.031
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.969	0.031
K92 Other diseases of digestive system	0.000	0.970	0.030
K77 Liver disorders in diseases classified elsewhere	0.000	0.970	0.030
K71 Toxic liver disease	0.000	0.970	0.030
D86.1 Sarcoidosis of lymph nodes	0.000	0.970	0.030
K73 Chronic hepatitis, not elsewhere classified	0.000	0.971	0.029
K74.0 Hepatic fibrosis	0.000	0.971	0.029
K72.1 Chronic hepatic failure	0.000	0.972	0.028
K75 Other inflammatory liver diseases	0.000	0.972	0.028
K90 Intestinal malabsorption	0.000	0.972	0.028
D86.3 Sarcoidosis of skin	0.000	0.972	0.028
K92.1 Melaena	0.000	0.972	0.028
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.972	0.028
K74.3 Primary biliary cirrhosis	0.000	0.972	0.028
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.972	0.028
K92.9 Disease of digestive system, unspecified	0.000	0.973	0.027
K74.4 Secondary biliary cirrhosis	0.000	0.974	0.026
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.974	0.026
K74.1 Hepatic sclerosis	0.000	0.974	0.026
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.975	0.025
K90.0 Coeliac disease	0.000	0.975	0.025
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.975	0.025
K74.5 Biliary cirrhosis, unspecified	0.000	0.976	0.024
N95.8 Other specified menopausal and perimenopausal disorders	0.023	0.977	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.977	0.023
K92.8 Other specified diseases of digestive system	0.000	0.978	0.022
K91.3 Postoperative intestinal obstruction	0.000	0.978	0.022
K75.8 Other specified inflammatory liver diseases	0.000	0.978	0.022
K75.0 Abscess of liver	0.000	0.978	0.022
K71.9 Toxic liver disease, unspecified	0.000	0.978	0.021
K71.8 Toxic liver disease with other disorders of liver	0.000	0.978	0.021
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.978	0.021
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.978	0.021
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.978	0.021
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.978	0.021
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.978	0.021
K71.2 Toxic liver disease with acute hepatitis	0.000	0.978	0.021
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.978	0.021
K71.0 Toxic liver disease with cholestasis	0.000	0.978	0.021
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.978	0.021
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.978	0.021
K91.4 Colostomy and enterostomy malfunction	0.000	0.979	0.021
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.979	0.021
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.979	0.021
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.979	0.021
K90.8 Other intestinal malabsorption	0.000	0.979	0.021
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.979	0.021
K73.9 Chronic hepatitis, unspecified	0.000	0.979	0.021
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.979	0.021
K75.9 Inflammatory liver disease, unspecified	0.000	0.979	0.021
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.979	0.021
K75.2 Nonspecific reactive hepatitis	0.000	0.979	0.021
K75.1 Phlebitis of portal vein	0.000	0.979	0.021
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.979	0.020
K90.3 Pancreatic steatorrhoea	0.000	0.979	0.020
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.979	0.020
K90.1 Tropical sprue	0.000	0.979	0.020
K91.5 Postcholecystectomy syndrome	0.000	0.980	0.020
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.020	0.980	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.020	0.980	0.000
C44.5 Skin of trunk	0.000	0.981	0.019
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.981	0.019
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.982	0.018
K93.1 Megacolon in Chagas' disease	0.000	0.982	0.018
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.982	0.018
K76 Other diseases of liver	0.000	0.982	0.018
K91.1 Postgastric surgery syndromes	0.000	0.983	0.017
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
K75.4 Autoimmune hepatitis	0.000	0.984	0.016
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.985	0.015
O94-O99 Other obstetric conditions, not elsewhere classified	0.015	0.985	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.986	0.014
K50-K52 Noninfective enteritis and colitis	0.000	0.986	0.014
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
K92.0 Haematemesis	0.000	0.987	0.013
T79.3 Post-traumatic wound infection, not elsewhere classified	0.013	0.987	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.987	0.013
K76.4 Peliosis hepatis	0.000	0.987	0.013
K76.3 Infarction of liver	0.000	0.987	0.013
K76.2 Central haemorrhagic necrosis of liver	0.000	0.987	0.013
O26.8 Other specified pregnancy-related conditions	0.013	0.987	0.000
Z97.8 Presence of other specified devices	0.000	0.988	0.012
D80-D89 Certain disorders involving the immune mechanism	0.000	0.988	0.012
K76.7 Hepatorenal syndrome	0.000	0.988	0.012
O26 Maternal care for other conditions predominantly related to pregnancy	0.012	0.988	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.988	0.012
K76.9 Liver disease, unspecified	0.000	0.988	0.012
K52 Other non-infective gastro-enteritis and colitis	0.000	0.988	0.012
K76.6 Portal hypertension	0.000	0.988	0.012
O36.9 Maternal care for foetal problem, unspecified	0.011	0.989	0.000
Z97 Presence of other devices	0.000	0.989	0.011
Z97.0 Presence of artificial eye	0.000	0.989	0.011
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
K76.1 Chronic passive congestion of liver	0.000	0.989	0.011
T79 Certain early complications of trauma, not elsewhere classified	0.011	0.989	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.011	0.989	0.000
Z97.4 Presence of external hearing-aid	0.000	0.989	0.011
O97 Death from sequelae of direct obstetric causes	0.011	0.989	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.011	0.989	0.000
O95 Obstetric death of unspecified cause	0.011	0.989	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.011	0.989	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.011	0.989	0.000
K65-K67 Diseases of peritoneum	0.000	0.989	0.011
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O26.2 Pregnancy care of habitual aborter	0.010	0.990	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.010	0.990	0.000
O36 Maternal care for other known or suspected foetal problems	0.010	0.990	0.000
O14.9 Preeclampsia, unspecified	0.010	0.990	0.000
O16 Unspecified maternal hypertension	0.010	0.990	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.990	0.010
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.990	0.010
T79.8 Other early complications of trauma	0.010	0.990	0.000
O26.0 Excessive weight gain in pregnancy	0.009	0.990	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.009	0.991	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.991	0.009
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.009	0.991	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.991	0.009
K52.3 Indeterminate colitis	0.000	0.991	0.009
D83 Common variable immunodeficiency	0.000	0.991	0.009
D82 Immunodeficiency associated with other major defects	0.000	0.991	0.009
D81 Combined immunodeficiencies	0.000	0.991	0.009
O28 Abnormal findings on antenatal screening of mother	0.009	0.991	0.000
O26.5 Maternal hypotension syndrome	0.009	0.991	0.000
O26.4 Herpes gestationis	0.009	0.991	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.009	0.991	0.000
O26.1 Low weight gain in pregnancy	0.009	0.991	0.000
O36.1 Maternal care for other isoimmunisation	0.009	0.991	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O48 Prolonged pregnancy	0.009	0.991	0.000
T79.6 Traumatic ischaemia of muscle	0.009	0.991	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.009	0.991	0.000
O14.1 Severe preeclampsia	0.009	0.991	0.000
T79.7 Traumatic subcutaneous emphysema	0.009	0.991	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.991	0.008
D84 Other immunodeficiencies	0.000	0.992	0.008
Z97.3 Presence of spectacles and contact lenses	0.000	0.992	0.008
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.992	0.008
O22 Venous complications in pregnancy	0.008	0.992	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.992	0.008
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.992	0.008
O30 Multiple gestation	0.008	0.992	0.000
O85-O92 Complications predominantly related to the puerperium	0.008	0.992	0.000
O40 Polyhydramnios	0.008	0.992	0.000
T79.9 Unspecified early complication of trauma	0.008	0.992	0.000
T79.5 Traumatic anuria	0.008	0.992	0.000
T79.4 Traumatic shock	0.008	0.992	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.008	0.992	0.000
T79.1 Fat embolism (traumatic)	0.008	0.992	0.000
T79.0 Air embolism (traumatic)	0.008	0.992	0.000
O29 Complications of anaesthesia during pregnancy	0.008	0.992	0.000
O25 Malnutrition in pregnancy	0.008	0.992	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.992	0.008
O96.9 Death from unspecified obstetric cause	0.008	0.992	0.000
O96.1 Death from indirect obstetric cause	0.008	0.992	0.000
O96.0 Death from direct obstetric cause	0.008	0.992	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.008	0.992	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.008	0.992	0.000
O97.0 Death from sequelae of direct obstetric cause	0.008	0.992	0.000
O24 Diabetes mellitus in pregnancy	0.008	0.992	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.992	0.008
O15 Eclampsia	0.008	0.992	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.008	0.992	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.008	0.992	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.992	0.008
O36.4 Maternal care for intra-uterine death	0.008	0.992	0.000
O26.9 Pregnancy-related condition, unspecified	0.008	0.992	0.000
O20 Haemorrhage in early pregnancy	0.008	0.992	0.000
O14.2 HELLP syndrome	0.008	0.992	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.008	0.992	0.000
O36.2 Maternal care for hydrops foetalis	0.008	0.992	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.008	0.992	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.992	0.008
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.992	0.008
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.007	0.992	0.000
O36.6 Maternal care for excessive foetal growth	0.007	0.993	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.007	0.993	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.007	0.993	0.000
O30.0 Twin pregnancy	0.007	0.993	0.000
O44 Placenta praevia	0.007	0.993	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.007	0.993	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.007	0.993	0.000
O12.1 Gestational proteinuria	0.007	0.993	0.000
O12.0 Gestational oedema	0.007	0.993	0.000
O31 Complications specific to multiple gestation	0.007	0.993	0.000
O36.5 Maternal care for poor foetal growth	0.007	0.993	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.007	0.993	0.000
O33 Maternal care for known or suspected disproportion	0.007	0.993	0.000
O45 Premature separation of placenta [abruptio placentae]	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.993	0.007
D89.3 Immune reconstitution syndrome	0.000	0.993	0.007
D89.1 Cryoglobulinaemia	0.000	0.993	0.007
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.993	0.007
D81.9 Combined immunodeficiency, unspecified	0.000	0.993	0.007
D81.8 Other combined immunodeficiencies	0.000	0.993	0.007
D81.7 Major histocompatibility complex class II deficiency	0.000	0.993	0.007
D81.6 Major histocompatibility complex class I deficiency	0.000	0.993	0.007
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.993	0.007
D81.4 Nezelof's syndrome	0.000	0.993	0.007
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.993	0.007
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.993	0.007
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.993	0.007
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.993	0.007
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.993	0.007
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.993	0.007
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.993	0.007
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.993	0.007
D82.2 Immunodeficiency with short-limbed stature	0.000	0.993	0.007
D82.1 Di George's syndrome	0.000	0.993	0.007
D82.0 Wiskott-Aldrich syndrome	0.000	0.993	0.007
D83.9 Common variable immunodeficiency, unspecified	0.000	0.993	0.007
D83.8 Other common variable immunodeficiencies	0.000	0.993	0.007
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.993	0.007
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.993	0.007
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.993	0.007
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.007	0.993	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.007	0.993	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.007	0.993	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.007	0.993	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.007	0.993	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.007	0.993	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.007	0.993	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.007	0.993	0.000
O36.8 Maternal care for other specified foetal problems	0.007	0.993	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.007	0.993	0.000
O12.2 Gestational oedema with proteinuria	0.006	0.993	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.006	0.993	0.000
O44.1 Placenta praevia with haemorrhage	0.006	0.993	0.000
O34.1 Maternal care for tumour of corpus uteri	0.007	0.993	0.000
O14.0 Moderate preeclampsia	0.006	0.993	0.000
O23 Infections of genito-urinary tract in pregnancy	0.006	0.994	0.000
D84.8 Other specified immunodeficiencies	0.000	0.994	0.006
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.994	0.006
O22.9 Venous complication in pregnancy, unspecified	0.006	0.994	0.000
O22.8 Other venous complications in pregnancy	0.006	0.994	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.006	0.994	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.006	0.994	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.006	0.994	0.000
O22.1 Genital varices in pregnancy	0.006	0.994	0.000
O21 Excessive vomiting in pregnancy	0.006	0.994	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.006	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.006	0.994	0.000
O89 Complications of anaesthesia during the puerperium	0.006	0.994	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.994	0.006
O30.9 Multiple gestation, unspecified	0.006	0.994	0.000
O30.8 Other multiple gestation	0.006	0.994	0.000
O30.2 Quadruplet pregnancy	0.006	0.994	0.000
O30.1 Triplet pregnancy	0.006	0.994	0.000
O22.4 Haemorrhoids in pregnancy	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
O88 Obstetric embolism	0.006	0.994	0.000
O85 Puerperal sepsis	0.006	0.994	0.000
O90 Complications of the puerperium, not elsewhere classified	0.006	0.994	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.006	0.994	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.006	0.994	0.000
O29.6 Failed or difficult intubation during pregnancy	0.006	0.994	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.006	0.994	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.006	0.994	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.006	0.994	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.006	0.994	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.006	0.994	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.006	0.994	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.006	0.994	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.006	0.994	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.006	0.994	0.000
O80-O84 Delivery	0.006	0.994	0.000
O87 Venous complications in the puerperium	0.006	0.994	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.994	0.006
K67.3 Tuberculous peritonitis	0.000	0.994	0.006
K67.2 Syphilitic peritonitis	0.000	0.994	0.006
K67.1 Gonococcal peritonitis	0.000	0.994	0.006
K67.0 Chlamydial peritonitis	0.000	0.994	0.006
O15.9 Eclampsia, unspecified as to time period	0.006	0.994	0.000
O15.2 Eclampsia in the puerperium	0.006	0.994	0.000
O15.1 Eclampsia in labour	0.006	0.994	0.000
O15.0 Eclampsia in pregnancy	0.006	0.994	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.994	0.006
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.006	0.994	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.006	0.994	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.006	0.994	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.006	0.994	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.006	0.994	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.006	0.994	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.006	0.994	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.994	0.006
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.994	0.006
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.994	0.006
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.994	0.006
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.994	0.006
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.994	0.006
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.994	0.006
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.994	0.006
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.994	0.006
O24.9 Diabetes mellitus in pregnancy, unspecified	0.006	0.994	0.000
O34.4 Maternal care for other abnormalities of cervix	0.006	0.994	0.000
O34.0 Maternal care for congenital malformation of uterus	0.006	0.994	0.000
O92.1 Cracked nipple associated with childbirth	0.006	0.994	0.000
D37.5 Rectum	0.000	0.994	0.006
D84.1 Defects in the complement system	0.000	0.994	0.005
K76.8 Other specified diseases of liver	0.000	0.994	0.006
L98.0 Pyogenic granuloma	0.006	0.994	0.000
O86 Other puerperal infections	0.006	0.994	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.005	0.994	0.000
O20.8 Other haemorrhage in early pregnancy	0.005	0.995	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
O46.8 Other antepartum haemorrhage	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.005	0.995	0.000
O34.6 Maternal care for abnormality of vagina	0.005	0.995	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.005	0.995	0.000
O31.8 Other complications specific to multiple gestation	0.005	0.995	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.005	0.995	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.005	0.995	0.000
O31.0 Papyraceous foetus	0.005	0.995	0.000
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
O33.8 Maternal care for disproportion of other origin	0.005	0.995	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.005	0.995	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.005	0.995	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.005	0.995	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.005	0.995	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.005	0.995	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.005	0.995	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.005	0.995	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.005	0.995	0.000
O45.8 Other premature separation of placenta	0.005	0.995	0.000
O45.0 Premature separation of placenta with coagulation defect	0.005	0.995	0.000
O33.9 Maternal care for disproportion, unspecified	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O45.9 Premature separation of placenta, unspecified	0.005	0.995	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.005	0.995	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.005	0.995	0.000
O34.3 Maternal care for cervical incompetence	0.005	0.995	0.000
K35-K38 Diseases of appendix	0.001	0.995	0.004
O92.7 Other and unspecified disorders of lactation	0.005	0.995	0.000
O92.6 Galactorrhoea	0.005	0.995	0.000
O92.5 Suppressed lactation	0.005	0.995	0.000
O92.4 Hypogalactia	0.005	0.995	0.000
O92.3 Agalactia	0.005	0.995	0.000
O92.0 Retracted nipple associated with childbirth	0.005	0.995	0.000
C62.9 Testis, unspecified	0.005	0.995	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.005	0.995	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
C90.0 Multiple myeloma	0.000	0.995	0.005
O92.2 Other and unspecified disorders of breast associated with childbirth	0.005	0.995	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
N81.3 Complete uterovaginal prolapse	0.005	0.995	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
S91.0 Open wound of ankle	0.005	0.995	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.005	0.995	0.000
W19.2 School, other institution and public administrative area	0.000	0.995	0.005
O21.8 Other vomiting complicating pregnancy	0.004	0.995	0.000
O21.2 Late vomiting of pregnancy	0.004	0.995	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.995	0.000
O23.5 Infections of the genital tract in pregnancy	0.005	0.995	0.000
O90.1 Disruption of perineal obstetric wound	0.005	0.995	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.005	0.995	0.000
O41.1 Infection of amniotic sac and membranes	0.005	0.995	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.004	0.995	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.6 Failed or difficult intubation during the puerperium	0.004	0.995	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.004	0.995	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.004	0.995	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.004	0.995	0.000
S90-S99 Injuries to the ankle and foot	0.005	0.995	0.000
O43 Placental disorders	0.004	0.995	0.000
O88.8 Other obstetric embolism	0.004	0.995	0.000
O88.3 Obstetric pyaemic and septic embolism	0.004	0.995	0.000
O88.2 Obstetric blood-clot embolism	0.004	0.995	0.000
O88.1 Amniotic fluid embolism	0.004	0.995	0.000
O88.0 Obstetric air embolism	0.004	0.995	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.004	0.995	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.995	0.000
O91.0 Infection of nipple associated with childbirth	0.004	0.995	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.995	0.005
T79-T79 Certain early complications of trauma	0.005	0.995	0.000
O90.5 Postpartum thyroiditis	0.004	0.995	0.000
O90.4 Postpartum acute renal failure	0.004	0.995	0.000
O90.3 Cardiomyopathy in the puerperium	0.004	0.995	0.000
O90.0 Disruption of Caesarean section wound	0.004	0.995	0.000
S91 Open wound of ankle and foot	0.005	0.995	0.000
O84 Multiple delivery	0.004	0.995	0.000
O83 Other assisted single delivery	0.004	0.995	0.000
O87.9 Venous complication in the puerperium, unspecified	0.004	0.995	0.000
O87.8 Other venous complications in the puerperium	0.004	0.995	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.004	0.995	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.004	0.995	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.004	0.995	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.995	0.000
O41.0 Oligohydramnios	0.004	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.004	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.995	0.004
O90.2 Haematoma of obstetric wound	0.004	0.995	0.000
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
O86.2 Urinary tract infection following delivery	0.004	0.996	0.000
O87.2 Haemorrhoids in the puerperium	0.004	0.996	0.000
O86.8 Other specified puerperal infections	0.004	0.996	0.000
O86.3 Other genito-urinary tract infections following delivery	0.004	0.996	0.000
O86.1 Other infection of genital tract following delivery	0.004	0.996	0.000
O81 Single delivery by forceps and vacuum extractor	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
O47 False labour	0.004	0.996	0.000
O21.0 Mild hyperemesis gravidarum	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations