TreeWAS – Variant ID: rs41997

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.9 Sarcoidosis, unspecified	0.091	0.909	0.000
D86 Sarcoidosis	0.069	0.931	0.000
D86.0 Sarcoidosis of lung	0.061	0.939	0.000
D80-D89 Certain disorders involving the immune mechanism	0.053	0.947	0.000
D86.8 Sarcoidosis of other and combined sites	0.052	0.948	0.000
D80 Immunodeficiency with predominantly antibody defects	0.050	0.950	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.049	0.951	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.047	0.953	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.045	0.955	0.000
D86.3 Sarcoidosis of skin	0.041	0.959	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.040	0.960	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.039	0.961	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.038	0.962	0.000
D81 Combined immunodeficiencies	0.038	0.962	0.000
D82 Immunodeficiency associated with other major defects	0.037	0.962	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.037	0.963	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.036	0.964	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.036	0.964	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.036	0.964	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.036	0.964	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.036	0.964	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.036	0.964	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.035	0.965	0.000
D83 Common variable immunodeficiency	0.033	0.967	0.000
D86.1 Sarcoidosis of lymph nodes	0.032	0.967	0.000
D89.3 Immune reconstitution syndrome	0.033	0.967	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.032	0.968	0.000
D84 Other immunodeficiencies	0.031	0.968	0.000
D89.1 Cryoglobulinaemia	0.030	0.970	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.030	0.970	0.000
D81.9 Combined immunodeficiency, unspecified	0.027	0.972	0.000
D81.8 Other combined immunodeficiencies	0.027	0.972	0.000
D81.7 Major histocompatibility complex class II deficiency	0.027	0.972	0.000
D81.6 Major histocompatibility complex class I deficiency	0.027	0.972	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.027	0.972	0.000
D81.4 Nezelof's syndrome	0.027	0.972	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.027	0.972	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.027	0.972	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.027	0.972	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.027	0.972	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.027	0.973	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.027	0.973	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.027	0.973	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.027	0.973	0.000
D82.2 Immunodeficiency with short-limbed stature	0.027	0.973	0.000
D82.0 Wiskott-Aldrich syndrome	0.027	0.973	0.000
D82.1 Di George's syndrome	0.026	0.974	0.000
D84.8 Other specified immunodeficiencies	0.025	0.975	0.000
D83.8 Other common variable immunodeficiencies	0.024	0.976	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.024	0.976	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.024	0.976	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.024	0.976	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.023	0.977	0.000
D84.1 Defects in the complement system	0.019	0.980	0.000
D83.9 Common variable immunodeficiency, unspecified	0.018	0.981	0.000
D84.9 Immunodeficiency, unspecified	0.016	0.984	0.000
H53.8 Other visual disturbances	0.013	0.987	0.000
Z33 Pregnant state, incidental	0.010	0.990	0.000
Z89.6 Acquired absence of leg above knee	0.010	0.990	0.000
D68.0 Von Willebrand's disease	0.009	0.991	0.000
R47.0 Dysphasia and aphasia	0.000	0.991	0.009
H53 Visual disturbances	0.008	0.992	0.000
H53.0 Amblyopia ex anopsia	0.008	0.992	0.000
H53.2 Diplopia	0.008	0.992	0.000
M50.2 Other cervical disk displacement	0.000	0.993	0.007
D68 Other coagulation defects	0.007	0.993	0.000
H53.3 Other disorders of binocular vision	0.007	0.993	0.000
Z89 Acquired absence of limb	0.007	0.993	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.007	0.993	0.000
Z98.1 Arthrodesis status	0.007	0.993	0.000
D68.5 Primary Thrombophilia	0.006	0.993	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.006	0.994	0.000
H53.6 Night blindness	0.006	0.994	0.000
H53.5 Colour vision deficiencies	0.006	0.994	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.006	0.994	0.000
Z89.2 Acquired absence of upper limb above wrist	0.006	0.994	0.000
Z89.4 Acquired absence of foot and ankle	0.006	0.994	0.000
D68.8 Other specified coagulation defects	0.006	0.994	0.000
H53.1 Subjective visual disturbances	0.006	0.994	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.006	0.994	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.006	0.994	0.000
D68.1 Hereditary factor XI deficiency	0.006	0.994	0.000
I08.0 Disorders of both mitral and aortic valves	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.005	0.995	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.005	0.995	0.000
Z89.1 Acquired absence of hand and wrist	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
D68.4 Acquired coagulation factor deficiency	0.005	0.995	0.000
Z89.9 Acquired absence of limb, unspecified	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
D55-D59 Haemolytic anaemias	0.005	0.995	0.000
D68.6 Other Thrombophilia	0.004	0.995	0.000
Z89.5 Acquired absence of leg at or below knee	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
H53.9 Visual disturbance, unspecified	0.004	0.996	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
Z52.4 Kidney donor	0.000	0.996	0.004
D57 Sickle-cell disorders	0.004	0.996	0.000
D58 Other hereditary haemolytic anaemias	0.004	0.996	0.000
D60-D64 Aplastic and other anaemias	0.004	0.996	0.000
D62 Acute posthaemorrhagic anaemia	0.004	0.996	0.000
D55 Anaemia due to enzyme disorders	0.003	0.996	0.000
D56 Thalassaemia	0.004	0.996	0.000
T40.2 Other opioids	0.000	0.996	0.004
K86.9 Disease of pancreas, unspecified	0.004	0.996	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.996	0.000
H53-H54 Visual disturbances and blindness	0.003	0.996	0.000
D58.2 Other haemoglobinopathies	0.003	0.997	0.000
K86 Other diseases of pancreas	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.003	0.997	0.000
Z52.0 Blood donor	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.003	0.997	0.000
D58.0 Hereditary spherocytosis	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.003
D57.1 Sickle-cell anaemia without crisis	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
H01.0 Blepharitis	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.003	0.997	0.000
D57.8 Other sickle-cell disorders	0.003	0.997	0.000
D57.3 Sickle-cell trait	0.003	0.997	0.000
D57.2 Double heterozygous sickling disorders	0.003	0.997	0.000
D57.0 Sickle-cell anaemia with crisis	0.003	0.997	0.000
D56.1 Beta thalassaemia	0.003	0.997	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.997	0.000
D58.1 Hereditary elliptocytosis	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
Z52 Donors of organs and tissues	0.000	0.997	0.003
D55.9 Anaemia due to enzyme disorder, unspecified	0.003	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.003	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.003	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.003	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.003	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.003	0.997	0.000
D56.9 Thalassaemia, unspecified	0.003	0.997	0.000
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.003	0.997	0.000
D56.3 Thalassaemia trait	0.003	0.997	0.000
W44.0 Home	0.003	0.997	0.000
H54.1 Blindness, one eye, low vision, other eye	0.003	0.997	0.000
K56.2 Volvulus	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
H26.8 Other specified cataract	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
I84.3 External thrombosed haemorrhoids	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.002
T40.8 Lysergide [LSD]	0.000	0.997	0.002
T40.7 Cannabis (derivatives)	0.000	0.997	0.002
T40.3 Methadone	0.000	0.997	0.002
T40.1 Heroin	0.000	0.997	0.002
T40.0 Opium	0.000	0.997	0.002
Z52.8 Donor of other organs and tissues	0.000	0.997	0.002
D61 Other aplastic anaemias	0.002	0.997	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
Z52.9 Donor of unspecified organ or tissue	0.000	0.998	0.002
Z52.7 Heart donor	0.000	0.998	0.002
Z52.6 Liver donor	0.000	0.998	0.002
Z52.5 Cornea donor	0.000	0.998	0.002
Z52.1 Skin donor	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
Z52.2 Bone donor	0.000	0.998	0.002
D73.0 Hyposplenism	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
D64 Other anaemias	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
Z93.0 Tracheostomy status	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
D64.8 Other specified anaemias	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
W45.6 Industrial and construction area	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
D50-D53 Nutritional anaemias	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
Y60.5 During heart catheterisation	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
D64.4 Congenital dyserythropoietic anaemia	0.002	0.998	0.000
D64.3 Other sideroblastic anaemias	0.002	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.002	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.002	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.002	0.998	0.000
M25.58 Pain in joint (Other)	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
Y60.8 During other surgical and medical care	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
W02.9 Unspecified place	0.000	0.998	0.002
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.000	0.998	0.002
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
D53 Other nutritional anaemias	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
K11.5 Sialolithiasis	0.000	0.998	0.002
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
S00.0 Superficial injury of scalp	0.000	0.998	0.002
Y60.4 During endoscopic examination	0.000	0.998	0.002
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.998	0.002
F20 Schizophrenia	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
W45.4 Street and highway	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
W45.8 Other specified place	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.998	0.000
W45 Foreign body or object entering through skin	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.998	0.000
F20.8 Other schizophrenia	0.001	0.998	0.000
M85.2 Hyperostosis of skull	0.001	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
W45.5 Trade and service area	0.001	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.998	0.002
R02 Gangrene, not elsewhere classified	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.001	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
F20.5 Residual schizophrenia	0.001	0.998	0.000
X50.6 Industrial and construction area	0.001	0.998	0.000
M85 Other disorders of bone density and structure	0.001	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.999	0.000
Y60.9 During unspecified surgical and medical care	0.000	0.999	0.001
Y60.7 During administration of enema	0.000	0.999	0.001
Y60.3 During injection or immunisation	0.000	0.999	0.001
Y60.2 During kidney dialysis or other perfusion	0.000	0.999	0.001
Y60.1 During infusion or transfusion	0.000	0.999	0.001
D53.9 Nutritional anaemia, unspecified	0.001	0.999	0.000
D53.8 Other specified nutritional anaemias	0.001	0.999	0.000
D53.2 Scorbutic anaemia	0.001	0.999	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.001	0.999	0.000
D53.0 Protein deficiency anaemia	0.001	0.999	0.000
M85.0 Fibrous dysplasia (monostotic)	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
D73.5 Infarction of spleen	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.999	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.000	0.999	0.001
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.999	0.000
K09.2 Other cysts of jaw	0.001	0.999	0.000
M85.9 Disorder of bone density and structure, unspecified	0.001	0.999	0.000
W45.9 Unspecified place	0.001	0.999	0.000
W45.0 Home	0.001	0.999	0.000
W45.7 Farm	0.001	0.999	0.000
W45.3 Sports and athletics area	0.001	0.999	0.000
W45.2 School, other institution and public administrative area	0.001	0.999	0.000
W45.1 Residential institution	0.001	0.999	0.000
Z03.3 Observation for suspected nervous system disorder	0.000	0.999	0.001
R72 Abnormality of white blood cells, not elsewhere classified	0.001	0.999	0.000
M85.29 Hyperostosis of skull-Site unspec	0.001	0.999	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.999	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.999	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.999	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.999	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.999	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.999	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
M85.4 Solitary bone cyst	0.001	0.999	0.000
R76.8 Other specified abnormal immunological findings in serum	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
M85.5 Aneurysmal bone cyst	0.001	0.999	0.000
M85.3 Osteitis condensans	0.001	0.999	0.000
M85.1 Skeletal fluorosis	0.001	0.999	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.001	0.999	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.999	0.000
D75.0 Familial erythrocytosis	0.001	0.999	0.000
F25.0 Schizoaffective disorder, manic type	0.001	0.999	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
Z50.0 Cardiac rehabilitation	0.000	0.999	0.001
D52 Folate deficiency anaemia	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.999	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.999	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.999	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.999	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.999	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.999	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.999	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.999	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.999	0.000
S70.0 Contusion of hip	0.000	0.999	0.001
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.000	0.999	0.001
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.999	0.001
Z35.6 Supervision of very young primigravida	0.000	0.999	0.001
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.999	0.001
Z45.8 Adjustment and management of other implanted devices	0.001	0.999	0.000
W44 Foreign body entering into or through eye or natural orifice	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.001	0.999	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.999	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.999	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.999	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.999	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.999	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.999	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.999	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.999	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.999	0.000
W45.09 Foreign body or object entering through skin: Home: During unspecified activity	0.001	0.999	0.000
W45.03 Foreign body or object entering through skin; Home; While engaged in other types of work	0.001	0.999	0.000
W45.99 Foreign body or object entering through skin; Unspecified place ;During unspecified activity	0.001	0.999	0.000
F25.1 Schizoaffective disorder, depressive type	0.001	0.999	0.000
H27.0 Aphakia	0.000	0.999	0.001
K62.6 Ulcer of anus and rectum	0.000	0.999	0.001
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.999	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.999	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.999	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.999	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.999	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.999	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.999	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.999	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.999	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.001	0.999	0.000
M02.39 Reiter's disease (Site unspecified)	0.001	0.999	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.001	0.999	0.000
M85.18 Skeletal fluorosis (Other)	0.001	0.999	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.001	0.999	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.001	0.999	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.001	0.999	0.000
M85.14 Skeletal fluorosis (Hand)	0.001	0.999	0.000
M85.13 Skeletal fluorosis (Forearm)	0.001	0.999	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.001	0.999	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.001	0.999	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.001	0.999	0.000
M85.39 Osteitis condensans (Site unspecified)	0.001	0.999	0.000
M85.38 Osteitis condensans (Other)	0.001	0.999	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.001	0.999	0.000
M85.36 Osteitis condensans (Lower leg)	0.001	0.999	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.001	0.999	0.000
M85.34 Osteitis condensans (Hand)	0.001	0.999	0.000
M85.33 Osteitis condensans (Forearm)	0.001	0.999	0.000
M85.32 Osteitis condensans (Upper arm)	0.001	0.999	0.000
M85.31 Osteitis condensans (Shoulder region)	0.001	0.999	0.000
M85.30 Osteitis condensans (Multiple sites)	0.001	0.999	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.001	0.999	0.000
M85.58 Aneurysmal bone cyst (Other)	0.001	0.999	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.001	0.999	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.001	0.999	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.001	0.999	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.001	0.999	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.001	0.999	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.001	0.999	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.001	0.999	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
M24.54 Contracture of joint (Hand)	0.000	0.999	0.001
M60.99 Myositis, unspecified (Site unspecified)	0.000	0.999	0.001
M71.06 Abscess of bursa (Lower leg)	0.001	0.999	0.000
C05.1 Soft palate	0.000	0.999	0.001
D52.8 Other folate deficiency anaemias	0.001	0.999	0.000
D52.1 Drug-induced folate deficiency anaemia	0.001	0.999	0.000
D52.0 Dietary folate deficiency anaemia	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.999	0.001
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.999	0.001
D48.0 Bone and articular cartilage	0.000	0.999	0.001
D75.8 Other specified diseases of blood and blood-forming organs	0.001	0.999	0.000
N89.5 Stricture and atresia of vagina	0.000	0.999	0.001
W44.5 Trade and service area	0.001	0.999	0.000
W44.7 Farm	0.001	0.999	0.000
W44.6 Industrial and construction area	0.001	0.999	0.000
W44.4 Street and highway	0.001	0.999	0.000
W44.3 Sports and athletics area	0.001	0.999	0.000
W44.2 School, other institution and public administrative area	0.001	0.999	0.000
W44.1 Residential institution	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
M41.5 Other secondary scoliosis	0.001	0.999	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.999	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
R78.0 Finding of alcohol in blood	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations