TreeWAS – Variant ID: rs4236709

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.80 Fractures of other parts of lower leg (closed)	0.049	0.951	0.000
Z90.1 Acquired absence of breast(s)	0.025	0.975	0.000
S82.8 Fractures of other parts of lower leg	0.023	0.977	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.980	0.020
S92 Fracture of foot, except ankle	0.018	0.982	0.000
S92.2 Fracture of other tarsal bone(s)	0.017	0.983	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.017	0.983	0.000
S82.86 Maisonneuve's fracture	0.017	0.983	0.000
S92.1 Fracture of talus	0.016	0.984	0.000
S92.0 Fracture of calcaneus	0.016	0.984	0.000
S82.81 Fractures of other parts of lower leg (open)	0.016	0.984	0.000
S92.4 Fracture of great toe	0.016	0.984	0.000
S92.00 Fracture of calcaneus (closed)	0.015	0.985	0.000
S92.10 Fracture of talus (closed)	0.015	0.985	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.986	0.014
S92.7 Multiple fractures of foot	0.014	0.986	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.986	0.014
S92.5 Fracture of other toe	0.014	0.986	0.000
S92.41 Fracture of great toe (open)	0.014	0.986	0.000
S92.11 Fracture of talus (open)	0.013	0.987	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.987	0.013
S92.9 Fracture of foot, unspecified	0.013	0.987	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.012	0.987	0.000
S92.40 Fracture of great toe (closed)	0.012	0.988	0.000
S92.01 Fracture of calcaneus (open)	0.012	0.988	0.000
J84 Other interstitial pulmonary diseases	0.000	0.988	0.012
S92.70 Multiple fractures of foot (closed)	0.012	0.988	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.989	0.011
S92.3 Fracture of metatarsal bone	0.011	0.989	0.000
S92.51 Fracture of other toe (open)	0.011	0.989	0.000
S92.50 Fracture of other toe (closed)	0.011	0.989	0.000
S92.71 Multiple fractures of foot (open)	0.010	0.990	0.000
Z46.8 Fitting and adjustment of other specified devices	0.010	0.990	0.000
S92.91 Fracture of foot, unspecified (open)	0.009	0.991	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.991	0.009
S92.90 Fracture of foot, unspecified (closed)	0.009	0.991	0.000
S92.31 Fracture of metatarsal bone (open)	0.008	0.992	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.992	0.008
C44.4 Skin of scalp and neck	0.000	0.992	0.008
S90-S99 Injuries to the ankle and foot	0.008	0.992	0.000
S90 Superficial injury of ankle and foot	0.007	0.993	0.000
S92.30 Fracture of metatarsal bone (closed)	0.007	0.993	0.000
K62.0 Anal polyp	0.000	0.993	0.007
S96 Injury of muscle and tendon at ankle and foot level	0.006	0.993	0.000
S82 Fracture of lower leg, including ankle	0.006	0.994	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
S90.8 Other superficial injuries of ankle and foot	0.006	0.994	0.000
S90.0 Contusion of ankle	0.006	0.994	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.006	0.994	0.000
M48.06 Spinal stenosis (Lumbar region)	0.006	0.994	0.000
S95 Injury of blood vessels at ankle and foot level	0.006	0.994	0.000
S94 Injury of nerves at ankle and foot level	0.006	0.994	0.000
Y60.0 During surgical operation	0.006	0.994	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.994	0.006
J31.0 Chronic rhinitis	0.000	0.994	0.006
S98 Traumatic amputation of ankle and foot	0.005	0.994	0.000
S82.4 Fracture of fibula alone	0.005	0.995	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.005	0.995	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.005	0.995	0.000
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.005	0.995	0.000
S90.2 Contusion of toe(s) with damage to nail	0.005	0.995	0.000
C73 Malignant neoplasm of thyroid gland	0.005	0.995	0.000
J80 Adult respiratory distress syndrome	0.000	0.995	0.005
M48.0 Spinal stenosis	0.005	0.995	0.000
S90.1 Contusion of toe(s) without damage to nail	0.005	0.995	0.000
M48.02 Spinal stenosis (Cervical region)	0.005	0.995	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.005	0.995	0.000
S97 Crushing injury of ankle and foot	0.005	0.995	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.005	0.995	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.005	0.995	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.005	0.995	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.005	0.995	0.000
S82.9 Fracture of lower leg, part unspecified	0.005	0.995	0.000
M48.04 Spinal stenosis (Thoracic region)	0.005	0.995	0.000
S82.40 Fracture of fibula alone (closed)	0.005	0.995	0.000
S93.4 Sprain and strain of ankle	0.005	0.995	0.000
S93.5 Sprain and strain of toe(s)	0.005	0.995	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.005	0.995	0.000
S82.2 Fracture of shaft of tibia	0.005	0.995	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.004	0.995	0.000
S82.0 Fracture of patella	0.005	0.995	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.004	0.995	0.000
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.004	0.996	0.000
S94.8 Injury of other nerves at ankle and foot level	0.004	0.996	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.004	0.996	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.004	0.996	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.004	0.996	0.000
S94.1 Injury of medial plantar nerve	0.004	0.996	0.000
S94.0 Injury of lateral plantar nerve	0.004	0.996	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.004	0.996	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.004	0.996	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.004	0.996	0.000
S95.2 Injury of dorsal vein of foot	0.004	0.996	0.000
S95.1 Injury of plantar artery of foot	0.004	0.996	0.000
S95.0 Injury of dorsal artery of foot	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.004	0.996	0.000
S82.1 Fracture of upper end of tibia	0.004	0.996	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.004	0.996	0.000
S98.3 Traumatic amputation of other parts of foot	0.004	0.996	0.000
S98.2 Traumatic amputation of two or more toes	0.004	0.996	0.000
S98.0 Traumatic amputation of foot at ankle level	0.004	0.996	0.000
S81 Open wound of lower leg	0.004	0.996	0.000
S82.7 Multiple fractures of lower leg	0.004	0.996	0.000
S82.21 Fracture of shaft of tibia (open)	0.004	0.996	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.004	0.996	0.000
S82.41 Fracture of fibula alone (open)	0.004	0.996	0.000
S86 Injury of muscle and tendon at lower leg level	0.004	0.996	0.000
S82.01 Fracture of patella (open)	0.004	0.996	0.000
S81.9 Open wound of lower leg, part unspecified	0.004	0.996	0.000
S98.1 Traumatic amputation of one toe	0.004	0.996	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.004	0.996	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.004	0.996	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
I51.8 Other ill-defined heart diseases	0.004	0.996	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.996	0.004
S97.0 Crushing injury of ankle	0.004	0.996	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.004	0.996	0.000
R03.1 Nonspecific low blood-pressure reading	0.004	0.996	0.000
J81 Pulmonary oedema	0.000	0.996	0.004
S82.3 Fracture of lower end of tibia	0.004	0.996	0.000
S93.0 Dislocation of ankle joint	0.004	0.996	0.000
M48 Other spondylopathies	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
S81.0 Open wound of knee	0.004	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.004	0.996	0.000
J31.2 Chronic pharyngitis	0.000	0.996	0.004
S82.6 Fracture of lateral malleolus	0.004	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
M48.09 Spinal stenosis (Site unspecified)	0.004	0.996	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.004	0.996	0.000
S99.8 Other specified injuries of ankle and foot	0.004	0.996	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.004	0.996	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.004	0.996	0.000
R41.3 Other amnesia	0.000	0.996	0.004
S93.40 Sprain of unspecified ligament of ankle	0.003	0.996	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.996	0.004
S99.7 Multiple injuries of ankle and foot	0.003	0.996	0.000
S87 Crushing injury of lower leg	0.004	0.996	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.996	0.000
J31.1 Chronic nasopharyngitis	0.000	0.996	0.004
N34.2 Other urethritis	0.000	0.996	0.004
R16.1 Splenomegaly, not elsewhere classified	0.004	0.996	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.003	0.996	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
C34 Malignant neoplasm of bronchus and lung	0.000	0.996	0.004
S84 Injury of nerves at lower leg level	0.003	0.996	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.996	0.004
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.003	0.996	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.997	0.000
S81.7 Multiple open wounds of lower leg	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.003	0.997	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.997	0.003
S80 Superficial injury of lower leg	0.003	0.997	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.003	0.997	0.000
Z00.0 General medical examination	0.003	0.997	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.003	0.997	0.000
S91.0 Open wound of ankle	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
S86.0 Injury of Achilles tendon	0.003	0.997	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.003	0.997	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.003	0.997	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.003	0.997	0.000
M48.4 Fatigue fracture of vertebra	0.003	0.997	0.000
M48.3 Traumatic spondylopathy	0.003	0.997	0.000
M48.2 Kissing spine	0.003	0.997	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.003	0.997	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
M48.9 Spondylopathy, unspecified	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
M48.8 Other specified spondylopathies	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
S87.0 Crushing injury of knee	0.003	0.997	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.003
C32.0 Glottis	0.000	0.997	0.003
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.997	0.003
S01.8 Open wound of other parts of head	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.003	0.997	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
S84.9 Injury of unspecified nerve at lower leg level	0.003	0.997	0.000
S84.8 Injury of other nerves at lower leg level	0.003	0.997	0.000
S84.7 Injury of multiple nerves at lower leg level	0.003	0.997	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.003	0.997	0.000
S84.0 Injury of tibial nerve at lower leg level	0.003	0.997	0.000
E07 Other disorders of thyroid	0.003	0.997	0.000
I51.0 Cardiac septal defect, acquired	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.003	0.997	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.997	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.997	0.000
S88.0 Traumatic amputation at knee level	0.002	0.997	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.003	0.997	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.997	0.003
S80.0 Contusion of knee	0.003	0.997	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.997	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.997	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.997	0.000
S85.5 Injury of popliteal vein	0.002	0.997	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.997	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.997	0.000
S85.2 Injury of peroneal artery	0.002	0.997	0.000
S85.0 Injury of popliteal artery	0.002	0.997	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.002	0.997	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
S86.00 Unspecified injury of Achilles tendon	0.002	0.997	0.000
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.002	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
Z00.5 Examination of potential donor of organ and tissue	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.002	0.997	0.000
Y65 Other misadventures during surgical and medical care	0.003	0.997	0.000
S89.7 Multiple injuries of lower leg	0.002	0.997	0.000
S89.1 Other specified injuries of lower leg	0.002	0.997	0.000
S89.0 Multiple injuries of lower leg	0.002	0.997	0.000
C32.9 Larynx, unspecified	0.000	0.997	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.003	0.997	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.002	0.997	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.002	0.997	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.002	0.997	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.002	0.997	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.002	0.997	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.002	0.997	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.002	0.997	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.002	0.997	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.002	0.997	0.000
M48.29 Kissing spine (Site unspecified)	0.002	0.997	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M48.27 Kissing spine (Lumbosacral region)	0.002	0.997	0.000
M48.26 Kissing spine (Lumbar region)	0.002	0.997	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.002	0.997	0.000
M48.24 Kissing spine (Thoracic region)	0.002	0.997	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.002	0.997	0.000
M48.22 Kissing spine (Cervical region)	0.002	0.997	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.002	0.997	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.002	0.997	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.002	0.997	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.002	0.997	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.002	0.997	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.002	0.997	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.002	0.997	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.002	0.997	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.002	0.997	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.002	0.997	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.002	0.997	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.002	0.997	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.002	0.997	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.002	0.997	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.002	0.997	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.002	0.997	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.002	0.997	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.002	0.997	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.002	0.997	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.002	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.997	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.002	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
C37 Malignant neoplasm of thymus	0.000	0.997	0.002
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
Y60.8 During other surgical and medical care	0.002	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.002	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
Z00.8 Other general examinations	0.002	0.998	0.000
E06 Thyroiditis	0.002	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.001
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
Z00.3 Examination for adolescent development state	0.002	0.998	0.000
Z00.2 Examination for period of rapid growth in childhood	0.002	0.998	0.000
Z00.1 Routine child health examination	0.002	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
C31 Malignant neoplasm of accessory sinuses	0.000	0.998	0.002
C33 Malignant neoplasm of trachea	0.000	0.998	0.002
H16 Keratitis	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.998	0.002
M48.86 Other specified spondylopathies (Lumbar region)	0.002	0.998	0.000
Y65.4 Failure to introduce or to remove other tube or instrument	0.002	0.998	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
C32.1 Supraglottis	0.000	0.998	0.002
C34.0 Main bronchus	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
H27.8 Other specified disorders of lens	0.000	0.998	0.002
Y65.5 Performance of inappropriate operation	0.002	0.998	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.002	0.998	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.002	0.998	0.000
Y65.1 Wrong fluid used in infusion	0.002	0.998	0.000
Y65.0 Mismatched blood used in transfusion	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.002	0.998	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
G51.0 Bell's palsy	0.000	0.998	0.002
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.002
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.998	0.002
Y64 Contaminated medical or biological substances	0.002	0.998	0.000
Y63 Failure in dosage during surgical and medical care	0.002	0.998	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.002	0.998	0.000
Y69 Unspecified misadventure during surgical and medical care	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.002	0.998	0.000
Z85.6 Personal history of leukaemia	0.002	0.998	0.000
Y66 Nonadministration of surgical and medical care	0.002	0.998	0.000
C31.0 Maxillary sinus	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
C30.0 Nasal cavity	0.000	0.998	0.002
G30 Alzheimer's disease	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
C30.1 Middle ear	0.000	0.998	0.002
C31.9 Accessory sinus, unspecified	0.000	0.998	0.002
C31.8 Overlapping lesion of accessory sinuses	0.000	0.998	0.002
C31.3 Sphenoidal sinus	0.000	0.998	0.002
C31.2 Frontal sinus	0.000	0.998	0.002
C31.1 Ethmoidal sinus	0.000	0.998	0.002
T40.2 Other opioids	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.000	0.998	0.002
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.998	0.002
C39.0 Upper respiratory tract, part unspecified	0.000	0.998	0.002
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.002	0.998	0.000
Y61.0 During surgical operation	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
Y61.8 During other surgical and medical care	0.002	0.998	0.000
Y61.7 During removal of catheter or packing	0.002	0.998	0.000
Y61.6 During aspiration, puncture and other catheterisation	0.002	0.998	0.000
Y61.5 During heart catheterisation	0.002	0.998	0.000
Y61.4 During endoscopic examination	0.002	0.998	0.000
Y61.3 During injection or immunisation	0.002	0.998	0.000
Y61.2 During kidney dialysis or other perfusion	0.002	0.998	0.000
Y61.1 During infusion or transfusion	0.002	0.998	0.000
H27.0 Aphakia	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.000	0.998	0.002
M49.5 Collapsed vertebra in diseases classified elsewhere	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.001	0.998	0.000
Y61.9 During unspecified surgical and medical care	0.001	0.998	0.000
Y62.9 During unspecified surgical and medical care	0.001	0.998	0.000
Y62.8 During other surgical and medical care	0.001	0.998	0.000
Y62.6 During aspiration, puncture and other catheterisation	0.001	0.998	0.000
Y62.5 During heart catheterisation	0.001	0.998	0.000
Y62.4 During endoscopic examination	0.001	0.998	0.000
Y62.3 During injection or immunisation	0.001	0.998	0.000
Y62.2 During kidney dialysis or other perfusion	0.001	0.998	0.000
Y62.1 During infusion or transfusion	0.001	0.998	0.000
Y62.0 During surgical operation	0.001	0.998	0.000
Y63.9 Failure in dosage during unspecified surgical and medical care	0.001	0.998	0.000
Y63.8 Failure in dosage during other surgical and medical care	0.001	0.998	0.000
Y63.6 Nonadministration of necessary drug, medicament or biological substance	0.001	0.998	0.000
Y63.5 Inappropriate temperature in local application and packing	0.001	0.998	0.000
Y63.4 Failure in dosage in electroshock or insulin-shock therapy	0.001	0.998	0.000
Y63.3 Inadvertent exposure of patient to radiation during medical care	0.001	0.998	0.000
Y63.2 Overdose of radiation given during therapy	0.001	0.998	0.000
Y63.1 Incorrect dilution of fluid used during infusion	0.001	0.998	0.000
Y63.0 Excessive amount of blood or other fluid given during transfusion or infusion	0.001	0.998	0.000
Y64.9 Contaminated medical or biological substance administered by unspecified means	0.001	0.998	0.000
Y64.8 Contaminated medical or biological substance administered by other means	0.001	0.998	0.000
Y64.1 Contaminated medical or biological substance, injected or used for immunisation	0.001	0.998	0.000
Y64.0 Contaminated medical or biological substance, transfused or infused	0.001	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.998	0.001
C38.2 Posterior mediastinum	0.000	0.998	0.001
C38.1 Anterior mediastinum	0.000	0.998	0.001
C38.0 Heart	0.000	0.998	0.001
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
E00-E07 Disorders of thyroid gland	0.002	0.998	0.000
V49.8 Car occupant [any] injured in other specified transport accidents	0.002	0.998	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
C38.3 Mediastinum, part unspecified	0.000	0.998	0.001
F52.0 Lack or loss of sexual desire	0.000	0.998	0.001
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.001	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.001	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
M49 Spondylopathies in diseases classified elsewhere	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations