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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs425283
log Bayes Factor = 0.169582
Chromosome 19   position 55,171,748  (GRCh37) Explore rs425283 on Ensembl!
Variant rs425283 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
R87.6 Abnormal cytological findings
0.210 0.790 0.000
R87 Abnormal findings in specimens from female genital organs
0.146 0.854 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.125 0.875 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.119 0.881 0.000
T39.1 4-Aminophenol derivatives
0.117 0.883 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.115 0.885 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.113 0.887 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.110 0.890 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.110 0.890 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.109 0.891 0.000
T39.0 Salicylates
0.106 0.894 0.000
R87.7 Abnormal histological findings
0.105 0.895 0.000
R87.8 Other abnormal findings
0.105 0.895 0.000
R87.5 Abnormal microbiological findings
0.105 0.895 0.000
R87.4 Abnormal immunological findings
0.105 0.895 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.105 0.895 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.105 0.895 0.000
R87.1 Abnormal level of hormones
0.105 0.895 0.000
R87.0 Abnormal level of enzymes
0.105 0.895 0.000
R87.9 Unspecified abnormal finding
0.104 0.896 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.101 0.899 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.100 0.900 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.097 0.903 0.000
T40.2 Other opioids
0.096 0.904 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.094 0.906 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.091 0.909 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.090 0.910 0.000
T39.4 Antirheumatics, not elsewhere classified
0.090 0.910 0.000
T39.2 Pyrazolone derivatives
0.090 0.910 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.089 0.911 0.000
T40.6 Other and unspecified narcotics
0.088 0.912 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.086 0.914 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.085 0.915 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.085 0.915 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.085 0.915 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.085 0.915 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.084 0.916 0.000
R86 Abnormal findings in specimens from male genital organs
0.084 0.916 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.082 0.918 0.000
T40.4 Other synthetic narcotics
0.082 0.918 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.081 0.919 0.000
T42.3 Barbiturates
0.081 0.919 0.000
T42.2 Succinimides and oxazolidinediones
0.081 0.919 0.000
T42.0 Hydantoin derivatives
0.081 0.919 0.000
T42.4 Benzodiazepines
0.081 0.919 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.079 0.921 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.078 0.922 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.078 0.922 0.000
T40.8 Lysergide [LSD]
0.078 0.922 0.000
T40.7 Cannabis (derivatives)
0.078 0.922 0.000
T40.5 Cocaine
0.078 0.922 0.000
T40.3 Methadone
0.078 0.922 0.000
T40.1 Heroin
0.078 0.922 0.000
T40.0 Opium
0.078 0.922 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.076 0.924 0.000
R83 Abnormal findings in cerebrospinal fluid
0.076 0.924 0.000
T36 Poisoning by systemic antibiotics
0.074 0.926 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.073 0.927 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.073 0.927 0.000
T37.5 Antiviral drugs
0.073 0.927 0.000
T37.4 Anthelminthics
0.073 0.927 0.000
T37.3 Other antiprotozoal drugs
0.073 0.927 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.073 0.927 0.000
T37.1 Antimycobacterial drugs
0.073 0.927 0.000
T37.0 Sulphonamides
0.073 0.927 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.072 0.928 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.072 0.928 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.072 0.928 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.071 0.929 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.070 0.930 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.070 0.930 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.067 0.932 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.067 0.932 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.067 0.932 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.067 0.932 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.067 0.932 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.067 0.932 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.067 0.932 0.000
T44.0 Anticholinesterase agents
0.067 0.932 0.000
T43.6 Psychostimulants with abuse potential
0.067 0.933 0.000
R86.0 Abnormal level of enzymes
0.066 0.933 0.000
T38.9 Other and unspecified hormone antagonists
0.065 0.935 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.065 0.935 0.000
T38.7 Androgens and anabolic congeners
0.065 0.935 0.000
T38.5 Other oestrogens and progestogens
0.065 0.935 0.000
T38.4 Oral contraceptives
0.065 0.935 0.000
T38.2 Antithyroid drugs
0.065 0.935 0.000
T38.1 Thyroid hormones and substitutes
0.065 0.935 0.000
T38.0 Glucocorticoids and synthetic analogues
0.065 0.935 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.065 0.935 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.065 0.935 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.065 0.935 0.000
T47.7 Emetics
0.065 0.935 0.000
T47.6 Antidiarrhoeal drugs
0.065 0.935 0.000
T47.5 Digestants
0.065 0.935 0.000
T47.4 Other laxatives
0.065 0.935 0.000
T47.3 Saline and osmotic laxatives
0.065 0.935 0.000
T47.2 Stimulant laxatives
0.065 0.935 0.000
T47.0 Histamine H(2)-receptor antagonists
0.065 0.935 0.000
R86.9 Unspecified abnormal finding
0.065 0.935 0.000
R86.8 Other abnormal findings
0.064 0.936 0.000
R89.7 Abnormal histological findings
0.064 0.936 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.063 0.936 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.064 0.936 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.063 0.937 0.000
K43 Ventral hernia
0.063 0.937 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.063 0.937 0.000
R85.5 Abnormal microbiological findings
0.063 0.937 0.000
T46.1 Calcium-channel blockers
0.063 0.937 0.000
T43.2 Other and unspecified antidepressants
0.062 0.938 0.000
T41.5 Therapeutic gases
0.061 0.939 0.000
T41.4 Anaesthetic, unspecified
0.061 0.939 0.000
T41.3 Local anaesthetics
0.061 0.939 0.000
T41.2 Other and unspecified general anaesthetics
0.061 0.939 0.000
T41.1 Intravenous anaesthetics
0.061 0.939 0.000
T41.0 Inhaled anaesthetics
0.061 0.939 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.061 0.939 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.061 0.939 0.000
T48.5 Anti-common-cold drugs
0.061 0.939 0.000
T48.4 Expectorants
0.061 0.939 0.000
T48.3 Antitussives
0.061 0.939 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.061 0.939 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.061 0.939 0.000
T48.0 Oxytocic drugs
0.061 0.939 0.000
T49.9 Topical agent, unspecified
0.061 0.939 0.000
T49.8 Other topical agents
0.061 0.939 0.000
T49.7 Dental drugs, topically applied
0.061 0.939 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.061 0.939 0.000
T49.5 Ophthalmological drugs and preparations
0.061 0.939 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.061 0.939 0.000
T49.3 Emollients, demulcents and protectants
0.061 0.939 0.000
T49.2 Local astringents and local detergents
0.061 0.939 0.000
T49.1 Antipruritics
0.061 0.939 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.061 0.939 0.000
K40-K46 Hernia
0.061 0.939 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.061 0.939 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.061 0.939 0.000
T46.7 Peripheral vasodilators
0.061 0.939 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.061 0.939 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.061 0.939 0.000
R86.7 Abnormal histological findings
0.060 0.940 0.000
R86.6 Abnormal cytological findings
0.060 0.940 0.000
R86.5 Abnormal microbiological findings
0.060 0.940 0.000
R86.4 Abnormal immunological findings
0.060 0.940 0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source
0.060 0.940 0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances
0.060 0.940 0.000
R86.1 Abnormal level of hormones
0.060 0.940 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.060 0.940 0.000
T43.9 Psychotropic drug, unspecified
0.059 0.941 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.059 0.941 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.059 0.941 0.000
R83.8 Other abnormal findings
0.059 0.941 0.000
K46 Unspecified abdominal hernia
0.058 0.942 0.000
K45 Other abdominal hernia
0.057 0.942 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.057 0.943 0.000
K42 Umbilical hernia
0.057 0.943 0.000
R89.9 Unspecified abnormal finding
0.057 0.943 0.000
R89.8 Other abnormal findings
0.057 0.943 0.000
R89.6 Abnormal cytological findings
0.057 0.943 0.000
R89.5 Abnormal microbiological findings
0.057 0.943 0.000
R89.4 Abnormal immunological findings
0.057 0.943 0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source
0.057 0.943 0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances
0.057 0.943 0.000
R89.1 Abnormal level of hormones
0.057 0.943 0.000
R89.0 Abnormal level of enzymes
0.057 0.943 0.000
T42.1 Iminostilbenes
0.057 0.943 0.000
R85.8 Other abnormal findings
0.057 0.943 0.000
T50.8 Diagnostic agents
0.056 0.944 0.000
T50.7 Analeptics and opioid receptor antagonists
0.056 0.944 0.000
T50.5 Appetite depressants
0.056 0.944 0.000
T50.4 Drugs affecting uric acid metabolism
0.056 0.944 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.056 0.944 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.056 0.944 0.000
T50.1 Loop [high-ceiling] diuretics
0.056 0.944 0.000
T50.0 Mineralocorticoids and their antagonists
0.056 0.944 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.055 0.944 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.055 0.945 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.055 0.945 0.000
R85.9 Unspecified abnormal finding
0.055 0.945 0.000
R85.6 Abnormal cytological findings
0.055 0.945 0.000
R85.4 Abnormal immunological findings
0.055 0.945 0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source
0.055 0.945 0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances
0.055 0.945 0.000
R85.1 Abnormal level of hormones
0.055 0.945 0.000
R85.0 Abnormal level of enzymes
0.055 0.945 0.000
R83.9 Unspecified abnormal finding
0.055 0.945 0.000
R83.7 Abnormal histological findings
0.055 0.945 0.000
R83.6 Abnormal cytological findings
0.055 0.945 0.000
R83.5 Abnormal microbiological findings
0.055 0.945 0.000
R83.4 Abnormal immunological findings
0.055 0.945 0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source
0.055 0.945 0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances
0.055 0.945 0.000
R83.1 Abnormal level of hormones
0.055 0.945 0.000
R83.0 Abnormal level of enzymes
0.055 0.945 0.000
T45.5 Anticoagulants
0.053 0.946 0.000
T36.9 Systemic antibiotic, unspecified
0.053 0.947 0.000
T36.8 Other systemic antibiotics
0.053 0.947 0.000
T36.7 Antifungal antibiotics, systemically used
0.053 0.947 0.000
T36.6 Rifamycins
0.053 0.947 0.000
T36.5 Aminoglycosides
0.053 0.947 0.000
T36.4 Tetracyclines
0.053 0.947 0.000
T36.3 Macrolides
0.053 0.947 0.000
T36.2 Chloramphenicol group
0.053 0.947 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.053 0.947 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.052 0.948 0.000
R84.9 Unspecified abnormal finding
0.051 0.948 0.000
R84.8 Other abnormal findings
0.051 0.948 0.000
R84.7 Abnormal histological findings
0.051 0.948 0.000
R84.6 Abnormal cytological findings
0.051 0.948 0.000
R84.4 Abnormal immunological findings
0.051 0.948 0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source
0.051 0.948 0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances
0.051 0.948 0.000
R84.1 Abnormal level of hormones
0.051 0.948 0.000
R84.0 Abnormal level of enzymes
0.051 0.948 0.000
R84.5 Abnormal microbiological findings
0.051 0.949 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.051 0.949 0.000
T45.2 Vitamins, not elsewhere classified
0.051 0.949 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.050 0.949 0.000
T45.8 Other primarily systemic and haematological agents
0.050 0.949 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.050 0.949 0.000
T45.6 Fibrinolysis-affecting drugs
0.050 0.949 0.000
T45.4 Iron and its compounds
0.050 0.949 0.000
T45.3 Enzymes, not elsewhere classified
0.050 0.949 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.051 0.949 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.049 0.951 0.000
K41 Femoral hernia
0.048 0.952 0.000
R85.7 Abnormal histological findings
0.047 0.953 0.000
O46.9 Antepartum haemorrhage, unspecified
0.047 0.953 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.047 0.953 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.045 0.954 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.045 0.954 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.045 0.954 0.000
K43.4 Parastomal hernia with gangrene
0.045 0.954 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.045 0.954 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.045 0.954 0.000
K43.1 Ventral hernia with gangrene
0.045 0.954 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.044 0.955 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.045 0.955 0.000
O34.1 Maternal care for tumour of corpus uteri
0.044 0.956 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.043 0.957 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.043 0.957 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.042 0.958 0.000
T36.0 Penicillins
0.042 0.958 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.042 0.958 0.000
K45.1 Other specified abdominal hernia with gangrene
0.041 0.958 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.041 0.959 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.041 0.959 0.000
K42.1 Umbilical hernia with gangrene
0.041 0.959 0.000
T45.0 Antiallergic and antiemetic drugs
0.040 0.959 0.000
O40 Polyhydramnios
0.041 0.959 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.040 0.960 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.040 0.960 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.039 0.961 0.000
K44 Diaphragmatic hernia
0.037 0.963 0.000
O34.0 Maternal care for congenital malformation of uterus
0.037 0.963 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.036 0.963 0.000
O34.3 Maternal care for cervical incompetence
0.036 0.963 0.000
K83.8 Other specified diseases of biliary tract
0.036 0.964 0.000
O46.8 Other antepartum haemorrhage
0.035 0.964 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.035 0.964 0.000
O34.6 Maternal care for abnormality of vagina
0.035 0.964 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.035 0.964 0.000
O34.4 Maternal care for other abnormalities of cervix
0.035 0.964 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.035 0.965 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.035 0.965 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.035 0.965 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.035 0.965 0.000
O43 Placental disorders
0.034 0.966 0.000
O31 Complications specific to multiple gestation
0.034 0.966 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.032 0.968 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.032 0.968 0.000
K83.0 Cholangitis
0.032 0.968 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.032 0.968 0.000
K83 Other diseases of biliary tract
0.031 0.969 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.031 0.969 0.000
O33 Maternal care for known or suspected disproportion
0.030 0.969 0.000
O44 Placenta praevia
0.030 0.970 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.030 0.970 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.030 0.970 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.030 0.970 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.030 0.970 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.030 0.970 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.030 0.970 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.030 0.970 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.030 0.970 0.000
O45 Premature separation of placenta [abruptio placentae]
0.029 0.971 0.000
O30 Multiple gestation
0.029 0.971 0.000
K44.1 Diaphragmatic hernia with gangrene
0.029 0.971 0.000
O43.0 Placental transfusion syndromes
0.028 0.972 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.028 0.972 0.000
O43.8 Other placental disorders
0.026 0.974 0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more
0.026 0.974 0.000
O31.8 Other complications specific to multiple gestation
0.026 0.974 0.000
O43.9 Placental disorder, unspecified
0.026 0.974 0.000
O36 Maternal care for other known or suspected foetal problems
0.025 0.975 0.000
O43.2 Morbidly adherent placenta
0.024 0.975 0.000
M31.3 Wegener's granulomatosis
0.025 0.975 0.000
O31.1 Continuing pregnancy after abortion of one foetus or more
0.024 0.976 0.000
O31.0 Papyraceous foetus
0.024 0.976 0.000
M31 Other necrotising vasculopathies
0.024 0.976 0.000
K83.1 Obstruction of bile duct
0.024 0.976 0.000
M24 Other specific joint derangements
0.024 0.976 0.000
M20-M25 Other joint disorders
0.023 0.977 0.000
K83.4 Spasm of sphincter of Oddi
0.023 0.977 0.000
O36.8 Maternal care for other specified foetal problems
0.023 0.977 0.000
K83.5 Biliary cyst
0.022 0.977 0.000
K83.3 Fistula of bile duct
0.022 0.977 0.000
K83.2 Perforation of bile duct
0.022 0.977 0.000
O33.8 Maternal care for disproportion of other origin
0.022 0.978 0.000
O33.7 Maternal care for disproportion due to other foetal deformities
0.022 0.978 0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus
0.022 0.978 0.000
O33.5 Maternal care for disproportion due to unusually large foetus
0.022 0.978 0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin
0.022 0.978 0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis
0.022 0.978 0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis
0.022 0.978 0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis
0.022 0.978 0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones
0.022 0.978 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.022 0.978 0.000
O33.9 Maternal care for disproportion, unspecified
0.022 0.978 0.000
M21 Other acquired deformities of limbs
0.022 0.978 0.000
K40 Inguinal hernia
0.021 0.979 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.021 0.979 0.000
M80-M85 Disorders of bone density and structure
0.021 0.979 0.000
O45.8 Other premature separation of placenta
0.021 0.979 0.000
O45.0 Premature separation of placenta with coagulation defect
0.021 0.979 0.000
O44.1 Placenta praevia with haemorrhage
0.021 0.979 0.000
M31.6 Other giant cell arteritis
0.021 0.979 0.000
M34 Systemic sclerosis
0.021 0.979 0.000
O30.9 Multiple gestation, unspecified
0.021 0.979 0.000
O30.8 Other multiple gestation
0.021 0.979 0.000
O30.2 Quadruplet pregnancy
0.021 0.979 0.000
O30.1 Triplet pregnancy
0.021 0.979 0.000
M81.98 Osteoporosis, unspecified (Other)
0.021 0.979 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.021 0.979 0.000
M81 Osteoporosis without pathological fracture
0.020 0.980 0.000
M34.9 Systemic sclerosis, unspecified
0.020 0.980 0.000
M81.9 Osteoporosis, unspecified
0.020 0.980 0.000
O43.1 Malformation of placenta
0.020 0.980 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.020 0.980 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.020 0.980 0.000
O42 Premature rupture of membranes
0.020 0.980 0.000
O45.9 Premature separation of placenta, unspecified
0.020 0.980 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.020 0.980 0.000
O36.4 Maternal care for intra-uterine death
0.020 0.980 0.000
M24.0 Loose body in joint
0.019 0.981 0.000
M84 Disorders of continuity of bone
0.019 0.981 0.000
M24.5 Contracture of joint
0.019 0.981 0.000
O30.0 Twin pregnancy
0.019 0.981 0.000
M24.7 Protrusio acetabuli
0.019 0.981 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.019 0.981 0.000
O41 Other disorders of amniotic fluid and membranes
0.019 0.981 0.000
O36.6 Maternal care for excessive foetal growth
0.019 0.981 0.000
M21.1 Varus deformity, not elsewhere classified
0.019 0.981 0.000
M24.6 Ankylosis of joint
0.019 0.981 0.000
M21.2 Flexion deformity
0.018 0.981 0.000
M33 Dermatopolymyositis
0.018 0.982 0.000
M24.1 Other articular cartilage disorders
0.018 0.982 0.000
M25 Other joint disorders, not elsewhere classified
0.018 0.982 0.000
M21.4 Flat foot [pes planus] (acquired)
0.018 0.982 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.018 0.982 0.000
O36.2 Maternal care for hydrops foetalis
0.018 0.982 0.000
O36.1 Maternal care for other isoimmunisation
0.018 0.982 0.000
M70-M79 Other soft tissue disorders
0.018 0.982 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.018 0.982 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.018 0.982 0.000
O32.8 Maternal care for other malpresentation of foetus
0.018 0.982 0.000
M24.2 Disorder of ligament
0.018 0.982 0.000
M31.9 Necrotising vasculopathy, unspecified
0.018 0.982 0.000
M31.8 Other specified necrotising vasculopathies
0.018 0.982 0.000
M31.7 Microscopic polyangiitis
0.018 0.982 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.018 0.982 0.000
M31.2 Lethal midline granuloma
0.018 0.982 0.000
M31.1 Thrombotic microangiopathy
0.018 0.982 0.000
M31.0 Hypersensitivity angiitis
0.018 0.982 0.000
M21.26 Flexion deformity (Lower leg)
0.018 0.982 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.018 0.982 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.018 0.982 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.017 0.982 0.000
M25.9 Joint disorder, unspecified
0.017 0.983 0.000
M72 Fibroblastic disorders
0.017 0.983 0.000
M24.9 Joint derangement, unspecified
0.017 0.983 0.000
M21.6 Other acquired deformities of ankle and foot
0.017 0.983 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.017 0.983 0.000
M85 Other disorders of bone density and structure
0.017 0.983 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.017 0.983 0.000
K83.9 Disease of biliary tract, unspecified
0.017 0.983 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.017 0.983 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.017 0.983 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.017 0.983 0.000
O32.3 Maternal care for face, brow and chin presentation
0.017 0.983 0.000
M24.02 Loose body in joint (Upper arm)
0.017 0.983 0.000
M21.7 Unequal limb length (acquired)
0.017 0.983 0.000
O47 False labour
0.017 0.983 0.000
M30 Polyarteritis nodosa and related conditions
0.016 0.983 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.016 0.983 0.000
M24.56 Contracture of joint (Lower leg)
0.016 0.983 0.000
M76 Enthesopathies of lower limb, excluding foot
0.016 0.984 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.016 0.984 0.000
M25.7 Osteophyte
0.016 0.984 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.016 0.984 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.016 0.984 0.000
M84.4 Pathological fracture, not elsewhere classified
0.016 0.984 0.000
M21.8 Other specified acquired deformities of limbs
0.016 0.984 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.016 0.984 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.016 0.984 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.016 0.984 0.000
M81.4 Drug-induced osteoporosis
0.016 0.984 0.000
M32 Systemic lupus erythematosus
0.016 0.984 0.000
M65-M68 Disorders of synovium and tendon
0.016 0.984 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.016 0.984 0.000
M21.9 Acquired deformity of limb, unspecified
0.016 0.984 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.016 0.984 0.000
M80 Osteoporosis with pathological fracture
0.016 0.984 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.016 0.984 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.016 0.984 0.000
M40-M43 Deforming dorsopathies
0.016 0.984 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.016 0.984 0.000
M33.2 Polymyositis
0.016 0.984 0.000
M99 Biomechanical lesions, not elsewhere classified
0.016 0.984 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.016 0.984 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.015 0.984 0.000
M24.01 Loose body in joint (Shoulder region)
0.016 0.984 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.015 0.984 0.000
O32.6 Maternal care for compound presentation
0.015 0.984 0.000
M83 Adult osteomalacia
0.015 0.984 0.000
M25.94 Joint disorder, unspecified (Hand)
0.015 0.984 0.000
M79.2 Neuralgia and neuritis, unspecified
0.015 0.985 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.015 0.985 0.000
M05-M14 Inflammatory polyarthropathies
0.015 0.985 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.015 0.985 0.000
M34.0 Progressive systemic sclerosis
0.015 0.985 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.015 0.985 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.015 0.985 0.000
M45-M49 Spondylopathies
0.015 0.985 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.015 0.985 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.015 0.985 0.000
M84.8 Other disorders of continuity of bone
0.015 0.985 0.000
M66 Spontaneous rupture of synovium and tendon
0.015 0.985 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.015 0.985 0.000
M22 Disorders of patella
0.015 0.985 0.000
M25.72 Osteophyte (Upper arm)
0.015 0.985 0.000
M84.3 Stress fracture, not elsewhere classified
0.015 0.985 0.000
M25.59 Pain in joint (Site unspecified)
0.015 0.985 0.000
M71 Other bursopathies
0.015 0.985 0.000
M85.6 Other cyst of bone
0.015 0.985 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.015 0.985 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.015 0.985 0.000
M81.8 Other osteoporosis
0.015 0.985 0.000
M81.6 Localised osteoporosis [Lequesne]
0.015 0.985 0.000
M81.5 Idiopathic osteoporosis
0.015 0.985 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.015 0.985 0.000
M81.1 Postoophorectomy osteoporosis
0.015 0.985 0.000
M86-M90 Other osteopathies
0.015 0.985 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.015 0.985 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.015 0.985 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.015 0.985 0.000
M60-M63 Disorders of muscles
0.015 0.985 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.015 0.985 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.015 0.985 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.015 0.985 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.015 0.985 0.000
M25.71 Osteophyte (Shoulder region)
0.015 0.985 0.000
M24.57 Contracture of joint (Ankle and foot)
0.014 0.985 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.014 0.985 0.000
M96.5 Postradiation scoliosis
0.014 0.985 0.000
M96.4 Postsurgical lordosis
0.014 0.985 0.000
M96.3 Postlaminectomy kyphosis
0.014 0.985 0.000
M96.2 Postradiation kyphosis
0.014 0.985 0.000
M79.1 Myalgia
0.014 0.985 0.000
M91-M94 Chondropathies
0.014 0.985 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.014 0.986 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.014 0.986 0.000
M34.8 Other forms of systemic sclerosis
0.014 0.986 0.000
M82 Osteoporosis in diseases classified elsewhere
0.014 0.986 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.014 0.986 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.014 0.986 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.014 0.986 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.014 0.986 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.014 0.986 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.014 0.986 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.014 0.986 0.000
M34.1 CR(E)ST syndrome
0.014 0.986 0.000
M81.0 Postmenopausal osteoporosis
0.014 0.986 0.000
O32.2 Maternal care for transverse and oblique lie
0.014 0.986 0.000
M00-M03 Infectious arthropathies
0.014 0.986 0.000
M49 Spondylopathies in diseases classified elsewhere
0.014 0.986 0.000
M24.09 Loose body in joint (Site unspecified)
0.014 0.986 0.000
M24.08 Loose body in joint (Other)
0.014 0.986 0.000
M24.06 Loose body in joint-Lower leg
0.014 0.986 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.014 0.986 0.000
M24.04 Loose body in joint (Hand)
0.014 0.986 0.000
M24.03 Loose body in joint (Forearm)
0.014 0.986 0.000
M24.00 Loose body in joint (Multiple sites)
0.014 0.986 0.000
M24.51 Contracture of joint (Shoulder region)
0.014 0.986 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.014 0.986 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.014 0.986 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.014 0.986 0.000
M84.9 Disorder of continuity of bone, unspecified
0.014 0.986 0.000
M84.2 Delayed union of fracture
0.014 0.986 0.000
M25.73 Osteophyte (Forearm)
0.014 0.986 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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