TreeWAS – Variant ID: rs4265793

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E87.6 Hypokalaemia	0.000	0.937	0.063
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.937	0.063
E70-E90 Metabolic disorders	0.000	0.943	0.057
E83 Disorders of mineral metabolism	0.000	0.945	0.055
E86 Volume depletion	0.000	0.947	0.053
E87.5 Hyperkalaemia	0.000	0.947	0.053
E83.5 Disorders of calcium metabolism	0.000	0.949	0.051
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.949	0.051
E87.3 Alkalosis	0.000	0.949	0.051
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.950	0.050
E73 Lactose intolerance	0.000	0.954	0.046
E83.3 Disorders of phosphorus metabolism	0.000	0.954	0.046
E87.4 Mixed disorder of acid-base balance	0.000	0.955	0.045
E74 Other disorders of carbohydrate metabolism	0.000	0.955	0.045
E87.7 Fluid overload	0.000	0.956	0.044
E87.2 Acidosis	0.000	0.956	0.044
E84 Cystic fibrosis	0.000	0.956	0.044
E87.0 Hyperosmolality and hypernatraemia	0.000	0.957	0.043
E83.1 Disorders of iron metabolism	0.000	0.957	0.042
E88 Other metabolic disorders	0.000	0.958	0.042
E70 Disorders of aromatic amino-acid metabolism	0.000	0.958	0.042
E79 Disorders of purine and pyrimidine metabolism	0.000	0.958	0.042
E83.4 Disorders of magnesium metabolism	0.000	0.959	0.041
E76 Disorders of glycosaminoglycan metabolism	0.000	0.959	0.041
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.959	0.041
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.959	0.041
E72 Other disorders of amino-acid metabolism	0.000	0.959	0.041
E77 Disorders of glycoprotein metabolism	0.000	0.960	0.040
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.960	0.040
E83.8 Other disorders of mineral metabolism	0.000	0.960	0.040
E83.2 Disorders of zinc metabolism	0.000	0.960	0.040
E83.0 Disorders of copper metabolism	0.000	0.960	0.040
E73.9 Lactose intolerance, unspecified	0.000	0.961	0.039
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.961	0.039
E85 Amyloidosis	0.000	0.962	0.038
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.965	0.035
E74.0 Glycogen storage disease	0.000	0.966	0.034
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.966	0.034
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.966	0.034
E73.8 Other lactose intolerance	0.000	0.966	0.033
E73.1 Secondary lactase deficiency	0.000	0.966	0.033
E73.0 Congenital lactase deficiency	0.000	0.966	0.033
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.967	0.033
E88.9 Metabolic disorder, unspecified	0.000	0.967	0.033
E84.9 Cystic fibrosis, unspecified	0.000	0.967	0.032
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.968	0.032
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.968	0.032
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.968	0.032
E74.2 Disorders of galactose metabolism	0.000	0.968	0.032
E74.1 Disorders of fructose metabolism	0.000	0.968	0.032
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.968	0.032
E70.3 Albinism	0.000	0.968	0.032
E84.8 Cystic fibrosis with other manifestations	0.000	0.968	0.031
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.968	0.031
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.969	0.031
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.969	0.030
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.969	0.030
E70.2 Disorders of tyrosine metabolism	0.000	0.969	0.030
E70.1 Other hyperphenylalaninaemias	0.000	0.969	0.030
E70.0 Classical phenylketonuria	0.000	0.969	0.030
E88.3 Tumour lysis syndrome	0.000	0.970	0.030
E88.2 Lipomatosis, not elsewhere classified	0.000	0.970	0.030
E88.8 Other specified metabolic disorders	0.000	0.970	0.030
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.970	0.030
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.970	0.030
E79.1 Lesch-Nyhan syndrome	0.000	0.970	0.030
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.970	0.030
E71.3 Disorders of fatty-acid metabolism	0.000	0.970	0.029
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.970	0.029
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.970	0.029
E71.0 Maple-syrup-urine disease	0.000	0.970	0.029
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.970	0.029
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.970	0.029
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.970	0.029
E76.2 Other mucopolysaccharidoses	0.000	0.970	0.029
E76.1 Mucopolysaccharidosis, type II	0.000	0.970	0.029
E76.0 Mucopolysaccharidosis, type I	0.000	0.970	0.029
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.971	0.029
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.971	0.029
E72.5 Disorders of glycine metabolism	0.000	0.971	0.029
E72.4 Disorders of ornithine metabolism	0.000	0.971	0.029
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.971	0.029
E72.2 Disorders of urea cycle metabolism	0.000	0.971	0.029
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.971	0.029
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.971	0.029
E77.1 Defects in glycoprotein degradation	0.000	0.971	0.029
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.971	0.029
E72.0 Disorders of amino-acid transport	0.000	0.971	0.028
E77.8 Other disorders of glycoprotein metabolism	0.000	0.971	0.028
E75.6 Lipid storage disorder, unspecified	0.000	0.972	0.028
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.972	0.028
E75.3 Sphingolipidosis, unspecified	0.000	0.972	0.028
E75.1 Other gangliosidosis	0.000	0.972	0.028
E75.0 GM2 gangliosidosis	0.000	0.972	0.028
E85.3 Secondary systemic amyloidosis	0.000	0.972	0.028
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.972	0.027
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.972	0.027
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.972	0.027
E75.2 Other sphingolipidosis	0.000	0.973	0.027
E85.9 Amyloidosis, unspecified	0.000	0.973	0.027
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.973	0.027
E75.5 Other lipid storage disorders	0.000	0.973	0.027
E85.8 Other amyloidosis	0.000	0.973	0.026
E85.4 Organ-limited amyloidosis	0.000	0.974	0.025
E89.4 Postprocedural ovarian failure	0.000	0.975	0.025
E80.2 Other porphyria	0.000	0.975	0.025
E89.1 Postprocedural hypoinsulinaemia	0.000	0.975	0.025
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.975	0.024
E80.5 Crigler-Najjar syndrome	0.000	0.975	0.024
E80.3 Defects of catalase and peroxydase	0.000	0.975	0.024
E80.0 Hereditary erythropoietic porphyria	0.000	0.975	0.024
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.975	0.024
E89.5 Postprocedural testicular hypofunction	0.000	0.976	0.024
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.976	0.024
E80.6 Other disorders of bilirubin metabolism	0.000	0.976	0.024
E80.1 Porphyria cutanea tarda	0.000	0.976	0.023
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.977	0.023
E20-E35 Disorders of other endocrine glands	0.000	0.977	0.023
E89.2 Postprocedural hypoparathyroidism	0.000	0.977	0.022
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.977	0.023
E89.3 Postprocedural hypopituitarism	0.000	0.978	0.022
E21.0 Primary hyperparathyroidism	0.000	0.978	0.022
E21.3 Hyperparathyroidism, unspecified	0.000	0.980	0.020
E80.4 Gilbert's syndrome	0.000	0.980	0.019
E89.0 Postprocedural hypothyroidism	0.000	0.981	0.019
E24 Cushing's syndrome	0.000	0.981	0.019
E21.4 Other specified disorders of parathyroid gland	0.000	0.981	0.019
E22 Hyperfunction of pituitary gland	0.000	0.981	0.019
E28 Ovarian dysfunction	0.000	0.981	0.019
E31 Polyglandular dysfunction	0.000	0.982	0.017
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.983	0.017
E40-E46 Malnutrition	0.000	0.983	0.017
E20 Hypoparathyroidism	0.000	0.983	0.017
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.983	0.017
E30 Disorders of puberty, not elsewhere classified	0.000	0.983	0.017
E25 Adrenogenital disorders	0.000	0.983	0.017
E26 Hyperaldosteronism	0.000	0.983	0.017
E34 Other endocrine disorders	0.000	0.983	0.016
E32 Diseases of thymus	0.000	0.983	0.016
E29 Testicular dysfunction	0.000	0.983	0.016
E21.2 Other hyperparathyroidism	0.000	0.984	0.016
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.984	0.015
E22.0 Acromegaly and pituitary gigantism	0.000	0.985	0.015
E28.2 Polycystic ovarian syndrome	0.000	0.985	0.015
E23 Hypofunction and other disorders of pituitary gland	0.000	0.985	0.015
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.985	0.015
E24.2 Drug-induced Cushing's syndrome	0.000	0.985	0.015
E27 Other disorders of adrenal gland	0.000	0.985	0.015
E00-E07 Disorders of thyroid gland	0.000	0.985	0.015
E24.0 Pituitary-dependent Cushing's disease	0.000	0.985	0.015
E24.9 Cushing's syndrome, unspecified	0.000	0.986	0.014
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.986	0.014
E24.8 Other Cushing's syndrome	0.000	0.986	0.014
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.986	0.014
E28.3 Primary ovarian failure	0.000	0.986	0.014
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.986	0.014
E24.3 Ectopic ACTH syndrome	0.000	0.986	0.014
E24.1 Nelson's syndrome	0.000	0.986	0.014
E22.8 Other hyperfunction of pituitary gland	0.000	0.986	0.014
E28.9 Ovarian dysfunction, unspecified	0.000	0.986	0.014
E28.8 Other ovarian dysfunction	0.000	0.986	0.014
E28.1 Androgen excess	0.000	0.986	0.014
E28.0 Oestrogen excess	0.000	0.986	0.014
E46 Unspecified protein-energy malnutrition	0.000	0.986	0.014
E22.1 Hyperprolactinaemia	0.000	0.986	0.013
E31.0 Autoimmune polyglandular failure	0.000	0.986	0.013
E26.9 Hyperaldosteronism, unspecified	0.000	0.987	0.013
E65-E68 Obesity and other hyperalimentation	0.000	0.987	0.013
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.987	0.013
E50-E64 Other nutritional deficiencies	0.000	0.987	0.013
E31.9 Polyglandular dysfunction, unspecified	0.000	0.987	0.013
E31.8 Other polyglandular dysfunction	0.000	0.987	0.013
E31.1 Polyglandular hyperfunction	0.000	0.987	0.013
E20.1 Pseudohypoparathyroidism	0.000	0.987	0.013
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.987	0.013
E45 Retarded development following protein-energy malnutrition	0.000	0.987	0.013
E43 Unspecified severe protein-energy malnutrition	0.000	0.987	0.013
E42 Marasmic kwashiorkor	0.000	0.987	0.013
E41 Nutritional marasmus	0.000	0.987	0.013
E40 Kwashiorkor	0.000	0.987	0.013
E20.9 Hypoparathyroidism, unspecified	0.000	0.987	0.012
E07 Other disorders of thyroid	0.000	0.987	0.012
E20.0 Idiopathic hypoparathyroidism	0.000	0.987	0.012
E30.9 Disorder of puberty, unspecified	0.000	0.988	0.012
E30.8 Other disorders of puberty	0.000	0.988	0.012
E30.1 Precocious puberty	0.000	0.988	0.012
E30.0 Delayed puberty	0.000	0.988	0.012
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.988	0.012
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.988	0.012
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.988	0.012
E25.9 Adrenogenital disorder, unspecified	0.000	0.988	0.012
E25.8 Other adrenogenital disorders	0.000	0.988	0.012
E34.8 Other specified endocrine disorders	0.000	0.988	0.012
E34.3 Short stature, not elsewhere classified	0.000	0.988	0.012
E20.8 Other hypoparathyroidism	0.000	0.988	0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.988	0.012
E29.9 Testicular dysfunction, unspecified	0.000	0.988	0.012
E26.8 Other hyperaldosteronism	0.000	0.988	0.012
E26.1 Secondary hyperaldosteronism	0.000	0.988	0.012
E34.5 Androgen resistance syndrome	0.000	0.988	0.012
E34.4 Constitutional tall stature	0.000	0.988	0.012
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.988	0.012
E34.1 Other hypersecretion of intestinal hormones	0.000	0.988	0.012
E32.1 Abscess of thymus	0.000	0.988	0.012
E32.0 Persistent hyperplasia of thymus	0.000	0.988	0.012
E29.8 Other testicular dysfunction	0.000	0.988	0.012
E29.0 Testicular hyperfunction	0.000	0.988	0.012
E34.9 Endocrine disorder, unspecified	0.000	0.988	0.012
E32.9 Disease of thymus, unspecified	0.000	0.988	0.012
E32.8 Other diseases of thymus	0.000	0.988	0.012
E34.0 Carcinoid syndrome	0.000	0.988	0.011
E29.1 Testicular hypofunction	0.000	0.989	0.011
E15 Nondiabetic hypoglycaemic coma	0.000	0.989	0.011
E23.6 Other disorders of pituitary gland	0.000	0.989	0.011
E23.1 Drug-induced hypopituitarism	0.000	0.989	0.011
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.989	0.011
E27.8 Other specified disorders of adrenal gland	0.000	0.989	0.011
E27.5 Adrenomedullary hyperfunction	0.000	0.989	0.011
E27.0 Other adrenocortical overactivity	0.000	0.989	0.011
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.989	0.011
E27.1 Primary adrenocortical insufficiency	0.000	0.989	0.011
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.989	0.011
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.989	0.011
E00 Congenital iodine-deficiency syndrome	0.000	0.989	0.011
E23.2 Diabetes insipidus	0.000	0.989	0.011
E23.7 Disorder of pituitary gland, unspecified	0.000	0.989	0.011
E26.0 Primary hyperaldosteronism	0.000	0.989	0.010
E27.9 Disorder of adrenal gland, unspecified	0.000	0.989	0.010
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.989	0.011
E07.9 Disorder of thyroid, unspecified	0.000	0.989	0.011
E23.0 Hypopituitarism	0.000	0.989	0.010
E27.2 Addisonian crisis	0.000	0.989	0.010
E16 Other disorders of pancreatic internal secretion	0.000	0.990	0.010
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.990	0.010
E05.9 Thyrotoxicosis, unspecified	0.000	0.990	0.010
H00.1 Chalazion	0.010	0.990	0.000
E06 Thyroiditis	0.000	0.990	0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.990	0.010
E63 Other nutritional deficiencies	0.000	0.990	0.010
E51 Thiamine deficiency	0.000	0.990	0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.990	0.010
E54 Ascorbic acid deficiency	0.000	0.990	0.009
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.990	0.010
E67 Other hyperalimentation	0.000	0.990	0.009
E68 Sequelae of hyperalimentation	0.000	0.990	0.009
E07.8 Other specified disorders of thyroid	0.000	0.990	0.009
E05.5 Thyroid crisis or storm	0.000	0.990	0.009
E05.4 Thyrotoxicosis factitia	0.000	0.990	0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.990	0.009
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.990	0.009
E50 Vitamin A deficiency	0.000	0.990	0.009
E60 Dietary zinc deficiency	0.000	0.990	0.009
E59 Dietary selenium deficiency	0.000	0.990	0.009
E52 Niacin deficiency [pellagra]	0.000	0.990	0.009
E58 Dietary calcium deficiency	0.000	0.990	0.009
E65 Localised adiposity	0.000	0.990	0.009
E44.1 Mild protein-energy malnutrition	0.000	0.991	0.009
E44.0 Moderate protein-energy malnutrition	0.000	0.991	0.009
E56 Other vitamin deficiencies	0.000	0.991	0.009
E07.1 Dyshormogenetic goitre	0.000	0.991	0.009
E07.0 Hypersecretion of calcitonin	0.000	0.991	0.009
D12.3 Transverse colon	0.009	0.991	0.000
E05.8 Other thyrotoxicosis	0.000	0.991	0.009
E53 Deficiency of other B group vitamins	0.000	0.991	0.008
E61 Deficiency of other nutrient elements	0.000	0.991	0.008
E16.1 Other hypoglycaemia	0.000	0.992	0.008
H25.8 Other senile cataract	0.000	0.992	0.008
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.992	0.008
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.992	0.008
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.992	0.008
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.992	0.008
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.992	0.008
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.992	0.008
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.992	0.008
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.992	0.008
E55 Vitamin D deficiency	0.000	0.992	0.008
E04 Other non-toxic goitre	0.000	0.992	0.008
E63.9 Nutritional deficiency, unspecified	0.000	0.992	0.008
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.992	0.008
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.992	0.008
E16.4 Abnormal secretion of gastrin	0.000	0.992	0.008
E16.3 Increased secretion of glucagon	0.000	0.992	0.008
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.992	0.008
E06.5 Other chronic thyroiditis	0.000	0.992	0.007
E06.4 Drug-induced thyroiditis	0.000	0.992	0.007
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.992	0.007
E06.0 Acute thyroiditis	0.000	0.992	0.007
E51.2 Wernicke's encephalopathy	0.000	0.992	0.007
E63.8 Other specified nutritional deficiencies	0.000	0.993	0.007
E63.1 Imbalance of constituents of food intake	0.000	0.993	0.007
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.993	0.007
E06.3 Autoimmune thyroiditis	0.000	0.993	0.007
E06.1 Subacute thyroiditis	0.000	0.993	0.007
E51.9 Thiamine deficiency, unspecified	0.000	0.993	0.007
E51.8 Other manifestations of thiamine deficiency	0.000	0.993	0.007
E51.1 Beriberi	0.000	0.993	0.007
N63 Unspecified lump in breast	0.007	0.993	0.000
E67.8 Other specified hyperalimentation	0.000	0.993	0.007
E67.3 Hypervitaminosis D	0.000	0.993	0.007
E67.2 Megavitamin-B6 syndrome	0.000	0.993	0.007
E67.1 Hypercarotenaemia	0.000	0.993	0.007
E67.0 Hypervitaminosis A	0.000	0.993	0.007
E03 Other hypothyroidism	0.000	0.993	0.007
E06.9 Thyroiditis, unspecified	0.000	0.993	0.007
E50.9 Vitamin A deficiency, unspecified	0.000	0.993	0.007
E50.8 Other manifestations of vitamin A deficiency	0.000	0.993	0.007
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.993	0.007
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.993	0.007
E50.5 Vitamin A deficiency with night blindness	0.000	0.993	0.007
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.993	0.007
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.993	0.007
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.993	0.007
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.993	0.007
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.993	0.007
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.993	0.007
E64.8 Sequelae of other nutritional deficiencies	0.000	0.993	0.007
E64.3 Sequelae of rickets	0.000	0.993	0.007
E64.2 Sequelae of vitamin C deficiency	0.000	0.993	0.007
E64.1 Sequelae of vitamin A deficiency	0.000	0.993	0.007
E64.0 Sequelae of protein-energy malnutrition	0.000	0.993	0.007
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.007	0.993	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.993	0.007
E56.8 Deficiency of other vitamins	0.000	0.993	0.007
E56.0 Deficiency of vitamin E	0.000	0.993	0.007
H00 Hordeolum and chalazion	0.007	0.993	0.000
E56.1 Deficiency of vitamin K	0.000	0.993	0.006
E53.9 Vitamin B deficiency, unspecified	0.000	0.993	0.006
E61.2 Magnesium deficiency	0.000	0.994	0.006
E53.1 Pyridoxine deficiency	0.000	0.994	0.006
E53.0 Riboflavin deficiency	0.000	0.994	0.006
E61.9 Deficiency of nutrient element, unspecified	0.000	0.994	0.006
E61.8 Deficiency of other specified nutrient elements	0.000	0.994	0.006
E61.7 Deficiency of multiple nutrient elements	0.000	0.994	0.006
E61.6 Vanadium deficiency	0.000	0.994	0.006
E61.5 Molybdenum deficiency	0.000	0.994	0.006
E61.4 Chromium deficiency	0.000	0.994	0.006
E61.3 Manganese deficiency	0.000	0.994	0.006
E61.0 Copper deficiency	0.000	0.994	0.006
D12.0 Caecum	0.006	0.994	0.000
E66 Obesity	0.000	0.994	0.006
G45.9 Transient cerebral ischaemic attack, unspecified	0.006	0.994	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.994	0.006
E55.0 Rickets, active	0.000	0.994	0.006
E04.8 Other specified non-toxic goitre	0.000	0.994	0.006
D12.9 Anus and anal canal	0.006	0.994	0.000
D12.4 Descending colon	0.006	0.994	0.000
D12.2 Ascending colon	0.006	0.994	0.000
D12.6 Colon, unspecified	0.006	0.994	0.000
E03.8 Other specified hypothyroidism	0.000	0.994	0.006
D12.7 Rectosigmoid junction	0.006	0.994	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.994	0.006
E16.2 Hypoglycaemia, unspecified	0.000	0.994	0.005
H00.0 Hordeolum and other deep inflammation of eyelid	0.005	0.994	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.995	0.005
E03.5 Myxoedema coma	0.000	0.995	0.005
E03.4 Atrophy of thyroid (acquired)	0.000	0.995	0.005
E03.3 Postinfectious hypothyroidism	0.000	0.995	0.005
D12.1 Appendix	0.005	0.995	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.995	0.005
E66.8 Other obesity	0.000	0.995	0.005
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.995	0.005
E61.1 Iron deficiency	0.000	0.995	0.005
E04.1 Non-toxic single thyroid nodule	0.000	0.995	0.005
E04.9 Non-toxic goitre, unspecified	0.000	0.995	0.005
E53.8 Deficiency of other specified B group vitamins	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.000	0.995	0.005
E66.1 Drug-induced obesity	0.000	0.995	0.005
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.004
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.995	0.005
D12.5 Sigmoid colon	0.004	0.996	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.996	0.004
G45 Transient cerebral ischaemic attacks and related syndromes	0.004	0.996	0.000
K29.5 Chronic gastritis, unspecified	0.004	0.996	0.000
N60-N64 Disorders of breast	0.004	0.996	0.000
H25 Senile cataract	0.000	0.996	0.004
G45.4 Transient global amnesia	0.004	0.996	0.000
N61 Inflammatory disorders of breast	0.004	0.996	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.996	0.004
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.004	0.996	0.000
H25.0 Senile incipient cataract	0.000	0.996	0.004
E78.6 Lipoprotein deficiency	0.000	0.996	0.003
N31.8 Other neuromuscular dysfunction of bladder	0.004	0.996	0.000
Z95.2 Presence of prosthetic heart valve	0.004	0.996	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.996	0.004
E78.3 Hyperchylomicronaemia	0.000	0.997	0.003
G45.0 Vertebro-basilar artery syndrome	0.003	0.997	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
E10-E14 Diabetes mellitus	0.000	0.997	0.003
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.003
E78.4 Other hyperlipidaemia	0.000	0.997	0.003
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.003	0.997	0.000
N60 Benign mammary dysplasia	0.003	0.997	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.003	0.997	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.003	0.997	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.997	0.003
H02.9 Disorder of eyelid, unspecified	0.003	0.997	0.000
H05 Disorders of orbit	0.003	0.997	0.000
H02 Other disorders of eyelid	0.003	0.997	0.000
G45.3 Amaurosis fugax	0.003	0.997	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.997	0.003
D12.8 Rectum	0.003	0.997	0.000
H25.1 Senile nuclear cataract	0.000	0.997	0.003
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
E78.8 Other disorders of lipoprotein metabolism	0.000	0.997	0.003
E78.2 Mixed hyperlipidaemia	0.000	0.997	0.003
N62 Hypertrophy of breast	0.003	0.997	0.000
N64 Other disorders of breast	0.003	0.997	0.000
H05.2 Exophthalmic conditions	0.003	0.997	0.000
N60.2 Fibroadenosis of breast	0.003	0.997	0.000
N60.9 Benign mammary dysplasia, unspecified	0.003	0.997	0.000
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
Z93.2 Ileostomy status	0.000	0.997	0.003
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.997	0.003
E13 Other specified diabetes mellitus	0.000	0.997	0.003
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.002
H03 Disorders of eyelid in diseases classified elsewhere	0.003	0.997	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
H02.2 Lagophthalmos	0.002	0.997	0.000
H05.1 Chronic inflammatory disorders of orbit	0.002	0.997	0.000
N64.4 Mastodynia	0.002	0.997	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.002	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.997	0.003
H05.9 Disorder of orbit, unspecified	0.002	0.997	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.002	0.997	0.000
H05.8 Other disorders of orbit	0.002	0.997	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
N64.3 Galactorrhoea not associated with childbirth	0.002	0.998	0.000
N64.2 Atrophy of breast	0.002	0.998	0.000
H05.3 Deformity of orbit	0.002	0.998	0.000
H02.4 Ptosis of eyelid	0.002	0.998	0.000
N64.0 Fissure and fistula of nipple	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
N97.9 Female infertility, unspecified	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.002	0.998	0.000
H05.4 Enophthalmos	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
N64.1 Fat necrosis of breast	0.002	0.998	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.998	0.002
E12.9 Without complications	0.000	0.998	0.002
E12.8 With unspecified complications	0.000	0.998	0.002
E12.7 With multiple complications	0.000	0.998	0.002
E12.6 With other specified complications	0.000	0.998	0.002
E12.5 With peripheral circulatory complications	0.000	0.998	0.002
E12.4 With neurological complications	0.000	0.998	0.002
E12.3 With ophthalmic complications	0.000	0.998	0.002
E12.2 With renal complications	0.000	0.998	0.002
E12.1 With ketoacidosis	0.000	0.998	0.002
E12.0 With coma	0.000	0.998	0.002
N64.9 Disorder of breast, unspecified	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.002	0.998	0.000
E13.9 Without complications	0.000	0.998	0.002
H02.8 Other specified disorders of eyelid	0.002	0.998	0.000
E13.8 With unspecified complications	0.000	0.998	0.002
E13.7 With multiple complications	0.000	0.998	0.002
E13.6 With other specified complications	0.000	0.998	0.002
E13.5 With peripheral circulatory complications	0.000	0.998	0.002
E13.4 With neurological complications	0.000	0.998	0.002
E13.2 With renal complications	0.000	0.998	0.002
E13.1 With ketoacidosis	0.000	0.998	0.002
E13.0 With coma	0.000	0.998	0.002
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.002	0.998	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H02.0 Entropion and trichiasis of eyelid	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.000	0.998	0.002
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.002	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.998	0.002
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
M25.7 Osteophyte	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
H04 Disorders of lachrymal system	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
K02.9 Dental caries, unspecified	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
H01.9 Inflammation of eyelid, unspecified	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.000	0.998	0.002
R07.2 Precordial pain	0.000	0.998	0.002
M25.78 Osteophyte (Other)	0.000	0.998	0.002
M25.73 Osteophyte (Forearm)	0.000	0.998	0.002
H04.9 Disorder of lachrymal system, unspecified	0.002	0.998	0.000
H04.6 Other changes in lachrymal passages	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations