TreeWAS – Variant ID: rs4273729

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.000	1.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
D86 Sarcoidosis	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.001	0.999
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.001	0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.999	0.001	0.000
M06.0 Seronegative rheumatoid arthritis	0.998	0.002	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.003	0.997
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.997	0.003	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.995	0.005	0.000
N48 Other disorders of penis	0.995	0.005	0.000
E03.9 Hypothyroidism, unspecified	0.994	0.006	0.000
D68 Other coagulation defects	0.000	0.006	0.994
N48.6 Balanitis xerotica obliterans	0.984	0.016	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.017	0.983
M06.34 Rheumatoid nodule (Hand)	0.981	0.019	0.000
D50-D53 Nutritional anaemias	0.000	0.020	0.980
K90 Intestinal malabsorption	0.000	0.021	0.979
D69 Purpura and other haemorrhagic conditions	0.000	0.021	0.979
N48.0 Leukoplakia of penis	0.979	0.021	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.973	0.027	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.028	0.972
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.971	0.029	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.031	0.969
L40 Psoriasis	0.963	0.037	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.960	0.040	0.000
D86.0 Sarcoidosis of lung	0.000	0.042	0.958
N40-N51 Diseases of male genital organs	0.957	0.043	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.047	0.953
K90.9 Intestinal malabsorption, unspecified	0.000	0.048	0.952
D52 Folate deficiency anaemia	0.000	0.050	0.950
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.950	0.050	0.000
N48.1 Balanoposthitis	0.948	0.052	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.944	0.056	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.062	0.938
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.065	0.935
M06.32 Rheumatoid nodule (Upper arm)	0.935	0.065	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.932	0.068	0.000
J33.9 Nasal polyp, unspecified	0.929	0.071	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.072	0.928
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.083	0.917
E78.0 Pure hypercholesterolaemia	0.913	0.087	0.000
D69.4 Other primary thrombocytopenia	0.000	0.088	0.912
D68.8 Other specified coagulation defects	0.000	0.089	0.911
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.910	0.090	0.000
D68.5 Primary Thrombophilia	0.000	0.094	0.906
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.904	0.096	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.902	0.098	0.000
L40.5 Arthropathic psoriasis	0.902	0.098	0.000
C82.0 Small cleaved cell, follicular	0.893	0.107	0.000
M06.4 Inflammatory polyarthropathy	0.890	0.110	0.000
N48.5 Ulcer of penis	0.888	0.112	0.000
N48.9 Disorder of penis, unspecified	0.883	0.117	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.125	0.875
N48.2 Other inflammatory disorders of penis	0.870	0.130	0.000
M07 Psoriatic and enteropathic arthropathies	0.869	0.131	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.132	0.868
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.865	0.135	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.865	0.135	0.000
M05.8 Other seropositive rheumatoid arthritis	0.863	0.137	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.858	0.142	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.153	0.847
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.154	0.846
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.839	0.161	0.000
D68.0 Von Willebrand's disease	0.000	0.165	0.835
M05.1 Rheumatoid lung disease	0.834	0.166	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.828	0.172	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.819	0.180	0.000
C82.3 Follicular lymphoma grade IIIa	0.819	0.180	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.189	0.811
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.808	0.192	0.000
N48.8 Other specified disorders of penis	0.807	0.193	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.806	0.194	0.000
D68.6 Other Thrombophilia	0.000	0.197	0.802
M08 Juvenile arthritis	0.801	0.199	0.000
L40.8 Other psoriasis	0.796	0.204	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.795	0.205	0.000
M07.3 Other psoriatic arthropathies	0.792	0.208	0.000
M06.33 Rheumatoid nodule (Forearm)	0.791	0.209	0.000
L40.4 Guttate psoriasis	0.788	0.212	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.787	0.213	0.000
M14 Arthropathies in other diseases classified elsewhere	0.783	0.217	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.217	0.783
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.779	0.221	0.000
K90.8 Other intestinal malabsorption	0.000	0.221	0.779
M45.X9 Ankylosing spondylitis (Site unspecified)	0.775	0.225	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.225	0.775
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.773	0.227	0.000
D68.9 Coagulation defect, unspecified	0.000	0.227	0.773
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.765	0.235	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.237	0.763
D86.3 Sarcoidosis of skin	0.000	0.238	0.762
D69.5 Secondary thrombocytopenia	0.000	0.243	0.757
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.757	0.243	0.000
N44 Torsion of testis	0.754	0.246	0.000
L40.0 Psoriasis vulgaris	0.752	0.248	0.000
M11 Other crystal arthropathies	0.751	0.249	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.746	0.254	0.000
C82.2 Large cell, follicular	0.743	0.257	0.000
N48.4 Impotence of organic origin	0.743	0.257	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.741	0.259	0.000
D55-D59 Haemolytic anaemias	0.000	0.261	0.739
C82.4 Follicular lymphoma grade IIIb	0.734	0.266	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.266	0.734
J33 Nasal polyp	0.734	0.266	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.267	0.733
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.732	0.268	0.000
D67 Hereditary factor IX deficiency	0.000	0.273	0.727
M05.2 Rheumatoid vasculitis	0.723	0.277	0.000
M12 Other specific arthropathies	0.723	0.277	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.723	0.277	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.000	0.283	0.717
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.716	0.284	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.715	0.285	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.715	0.285	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.715	0.285	0.000
D50 Iron deficiency anaemia	0.000	0.288	0.712
D86.8 Sarcoidosis of other and combined sites	0.000	0.290	0.710
D89.3 Immune reconstitution syndrome	0.000	0.295	0.705
J33.0 Polyp of nasal cavity	0.705	0.295	0.000
D89.1 Cryoglobulinaemia	0.000	0.296	0.704
D82 Immunodeficiency associated with other major defects	0.000	0.297	0.703
K90.3 Pancreatic steatorrhoea	0.000	0.298	0.702
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.298	0.702
K90.1 Tropical sprue	0.000	0.298	0.702
D69.8 Other specified haemorrhagic conditions	0.000	0.298	0.702
M45 Ankylosing spondylitis	0.700	0.300	0.000
E05.5 Thyroid crisis or storm	0.000	0.303	0.697
E05.4 Thyrotoxicosis factitia	0.000	0.303	0.697
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.303	0.697
D53 Other nutritional anaemias	0.000	0.303	0.697
C82.6 Cutaneous follicle centre lymphoma	0.696	0.304	0.000
C82.5 Diffuse follicle centre lymphoma	0.696	0.304	0.000
M06.1 Adult-onset Still's disease	0.694	0.306	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.308	0.692
L40.2 Acrodermatitis continua	0.691	0.309	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.690	0.310	0.000
M14.6 Neuropathic arthropathy	0.687	0.313	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.686	0.314	0.000
L40.1 Generalised pustular psoriasis	0.683	0.317	0.000
D52.8 Other folate deficiency anaemias	0.000	0.319	0.681
D52.1 Drug-induced folate deficiency anaemia	0.000	0.319	0.681
D52.0 Dietary folate deficiency anaemia	0.000	0.319	0.681
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.679	0.320	0.000
D69.1 Qualitative platelet defects	0.000	0.326	0.674
L40.3 Pustulosis palmaris et plantaris	0.673	0.326	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.326	0.674
M07.36 Other psoriatic arthropathies (Lower leg)	0.672	0.328	0.000
D83 Common variable immunodeficiency	0.000	0.329	0.671
M05.19 Rheumatoid lung disease (Site unspecified)	0.670	0.330	0.000
D84 Other immunodeficiencies	0.000	0.330	0.669
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.335	0.664
M05.10 Rheumatoid lung disease (Multiple sites)	0.662	0.338	0.000
M08.0 Juvenile rheumatoid arthritis	0.660	0.340	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.340	0.660
N48.3 Priapism	0.651	0.348	0.000
D59 Acquired haemolytic anaemia	0.000	0.350	0.650
M06.46 Inflammatory polyarthropathy (Lower leg)	0.646	0.354	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.354	0.646
M06.48 Inflammatory polyarthropathy (Other)	0.638	0.362	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.638	0.362	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.638	0.362	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.638	0.362	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.638	0.362	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.638	0.362	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.638	0.362	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.374	0.626
M07.5 Arthropathy in ulcerative colitis	0.623	0.377	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.623	0.377	0.000
M07.2 Psoriatic spondylitis	0.623	0.377	0.000
M07.1 Arthritis mutilans	0.623	0.377	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.623	0.377	0.000
L40-L45 Papulosquamous disorders	0.620	0.380	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.619	0.381	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.619	0.381	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.619	0.381	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.619	0.381	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.619	0.381	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.619	0.381	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.619	0.381	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.619	0.381	0.000
E05.8 Other thyrotoxicosis	0.000	0.384	0.616
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.385	0.615
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.613	0.387	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.391	0.608
D51.2 Transcobalamin II deficiency	0.000	0.393	0.607
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.393	0.607
C34.9 Bronchus or lung, unspecified	0.000	0.394	0.606
N49.2 Inflammatory disorders of scrotum	0.606	0.394	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.396	0.604
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.398	0.602
D59.1 Other autoimmune haemolytic anaemias	0.000	0.399	0.601
M07.38 Other psoriatic arthropathies (Other)	0.600	0.400	0.000
M05.18 Rheumatoid lung disease (Other)	0.598	0.402	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.598	0.402	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.598	0.402	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.598	0.402	0.000
M05.14 Rheumatoid lung disease (Hand)	0.598	0.402	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.598	0.402	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.598	0.402	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.598	0.402	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.598	0.402	0.000
M11.2 Other chondrocalcinosis	0.594	0.405	0.000
E03 Other hypothyroidism	0.495	0.408	0.097
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.408	0.592
D69.0 Allergic purpura	0.000	0.409	0.591
C34.3 Lower lobe, bronchus or lung	0.000	0.416	0.584
M14.2 Diabetic arthropathy	0.580	0.420	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.425	0.575
M08.9 Juvenile arthritis, unspecified	0.574	0.426	0.000
M08.8 Other juvenile arthritis	0.574	0.426	0.000
M08.4 Pauciarticular juvenile arthritis	0.574	0.426	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.574	0.426	0.000
M08.1 Juvenile ankylosing spondylitis	0.574	0.426	0.000
M07.6 Other enteropathic arthropathies	0.574	0.426	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.428	0.572
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.572	0.428	0.000
M08.2 Juvenile arthritis with systemic onset	0.571	0.428	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.567	0.432	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.567	0.432	0.000
D60-D64 Aplastic and other anaemias	0.000	0.437	0.563
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.561	0.438	0.000
M14.4 Arthropathy in amyloidosis	0.561	0.438	0.000
M14.3 Lipoid dermatoarthritis	0.561	0.438	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.561	0.438	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.561	0.438	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.561	0.438	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.554	0.446	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.554	0.446	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.449	0.551
G36 Other acute disseminated demyelination	0.000	0.449	0.551
N40 Hyperplasia of prostate	0.550	0.450	0.000
C21.1 Anal canal	0.549	0.451	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.548	0.451	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.548	0.451	0.000
N51.2 Balanitis in diseases classified elsewhere	0.545	0.455	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.544	0.456	0.000
C21.0 Anus, unspecified	0.542	0.458	0.000
D84.1 Defects in the complement system	0.000	0.458	0.542
D66 Hereditary factor VIII deficiency	0.000	0.459	0.541
J33.1 Polypoid sinus degeneration	0.541	0.459	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.540	0.460	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.461	0.539
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.461	0.539
M11.1 Familial chondrocalcinosis	0.539	0.461	0.000
M11.0 Hydroxyapatite deposition disease	0.539	0.461	0.000
C21 Malignant neoplasm of anus and anal canal	0.539	0.461	0.000
M11.9 Crystal arthropathy, unspecified	0.536	0.464	0.000
M12.2 Villonodular synovitis (pigmented)	0.534	0.465	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.531	0.469	0.000
D55 Anaemia due to enzyme disorders	0.000	0.470	0.530
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.470	0.530
D50.1 Sideropenic dysphagia	0.000	0.471	0.529
C34.2 Middle lobe, bronchus or lung	0.000	0.471	0.529
M12.3 Palindromic rheumatism	0.528	0.471	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.526	0.474	0.000
M12.5 Traumatic arthropathy	0.525	0.475	0.000
D61 Other aplastic anaemias	0.000	0.478	0.522
M05.28 Rheumatoid vasculitis (Other)	0.519	0.481	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.519	0.481	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.519	0.481	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.519	0.481	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.519	0.481	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.519	0.481	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.519	0.481	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.519	0.481	0.000
M12.4 Intermittent hydrarthrosis	0.518	0.481	0.000
M12.1 Kaschin-Beck disease	0.518	0.481	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.518	0.481	0.000
D82.1 Di George's syndrome	0.000	0.482	0.518
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.514	0.485	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.514	0.486	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.514	0.486	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.486	0.514
D81.8 Other combined immunodeficiencies	0.000	0.486	0.514
D81.7 Major histocompatibility complex class II deficiency	0.000	0.486	0.514
D81.6 Major histocompatibility complex class I deficiency	0.000	0.486	0.514
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.486	0.514
D81.4 Nezelof's syndrome	0.000	0.486	0.514
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.486	0.514
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.486	0.514
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.486	0.514
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.486	0.514
M06.88 Other specified rheumatoid arthritis (Other)	0.513	0.487	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.513	0.487	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.513	0.487	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.513	0.487	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.513	0.487	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.513	0.487	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.513	0.487	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.513	0.487	0.000
M11.8 Other specified crystal arthropathies	0.513	0.487	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.510	0.489	0.000
L42 Pityriasis rosea	0.510	0.490	0.000
C34.0 Main bronchus	0.000	0.492	0.508
L43 Lichen planus	0.507	0.493	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.495	0.504
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.495	0.504
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.495	0.504
D82.2 Immunodeficiency with short-limbed stature	0.000	0.495	0.504
D82.0 Wiskott-Aldrich syndrome	0.000	0.495	0.504
D56 Thalassaemia	0.000	0.496	0.504
N45 Orchitis and epididymitis	0.504	0.496	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.502	0.497	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.502	0.498	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.502	0.498	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.502	0.498	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.502	0.498	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.502	0.498	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.502	0.498	0.000
D53.8 Other specified nutritional anaemias	0.000	0.500	0.499
D53.2 Scorbutic anaemia	0.000	0.500	0.499
D53.0 Protein deficiency anaemia	0.000	0.500	0.499
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.499	0.501	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.502	0.498
M06.19 Adult-onset Still's disease (Site unspecified)	0.498	0.502	0.000
M06.18 Adult-onset Still's disease (Other)	0.498	0.502	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.498	0.502	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.498	0.502	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.498	0.502	0.000
M06.14 Adult-onset Still's disease (Hand)	0.498	0.502	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.498	0.502	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.498	0.502	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.498	0.502	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.505	0.495
M12.8 Other specific arthropathies, not elsewhere classified	0.490	0.509	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.512	0.488
D80 Immunodeficiency with predominantly antibody defects	0.000	0.514	0.486
G37.5 Concentric sclerosis [Balo]	0.000	0.517	0.483
G37.4 Subacute necrotising myelitis	0.000	0.517	0.483
G37.2 Central pontine myelinolysis	0.000	0.517	0.483
G37.1 Central demyelination of corpus callosum	0.000	0.517	0.483
G37.0 Diffuse sclerosis	0.000	0.517	0.483
D57 Sickle-cell disorders	0.000	0.518	0.482
D83.8 Other common variable immunodeficiencies	0.000	0.519	0.481
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.519	0.481
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.519	0.481
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.519	0.481
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.520	0.480
C34.8 Overlapping lesion of bronchus and lung	0.000	0.523	0.477
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.524	0.476
M06.10 Adult-onset Still's disease (Multiple sites)	0.475	0.525	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.525	0.475
M08.08 Juvenile rheumatoid arthritis (Other)	0.473	0.526	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.473	0.526	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.473	0.526	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.473	0.526	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.473	0.526	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.473	0.526	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.473	0.526	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.473	0.526	0.000
D84.8 Other specified immunodeficiencies	0.000	0.533	0.467
M45.X6 Ankylosing spondylitis (Lumbar region)	0.467	0.533	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.534	0.466
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.534	0.466
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.534	0.466
D59.3 Haemolytic-uraemic syndrome	0.000	0.534	0.466
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.534	0.466
E03.0 Congenital hypothyroidism with diffuse goitre	0.406	0.539	0.055
M11.26 Other chondrocalcinosis (Lower leg)	0.460	0.540	0.000
M13 Other arthritis	0.455	0.545	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.454	0.546	0.000
L44 Other papulosquamous disorders	0.451	0.548	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.450	0.550	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.447	0.553	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.447	0.553	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.447	0.553	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.447	0.553	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.447	0.553	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.447	0.553	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.447	0.553	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.447	0.553	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.447	0.553	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.447	0.553	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.447	0.553	0.000
M07.18 Arthritis mutilans (Other)	0.447	0.553	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.447	0.553	0.000
M07.16 Arthritis mutilans (Lower leg)	0.447	0.553	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.447	0.553	0.000
M07.14 Arthritis mutilans (Hand)	0.447	0.553	0.000
M07.13 Arthritis mutilans (Forearm)	0.447	0.553	0.000
M07.12 Arthritis mutilans (Upper arm)	0.447	0.553	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.447	0.553	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.447	0.553	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.447	0.553	0.000
M07.28 Psoriatic spondylitis (Other)	0.447	0.553	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.447	0.553	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.447	0.553	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.447	0.553	0.000
M07.24 Psoriatic spondylitis (Hand)	0.447	0.553	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.447	0.553	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.447	0.553	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.447	0.553	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.447	0.553	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.447	0.553	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.447	0.553	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.447	0.553	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.447	0.553	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.447	0.553	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.447	0.553	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.447	0.553	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.447	0.553	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.447	0.553	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.447	0.553	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.447	0.553	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.447	0.553	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.447	0.553	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.447	0.553	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.447	0.553	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.447	0.553	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.447	0.553	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.447	0.553	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.447	0.553	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.447	0.553	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.553	0.447
D69.9 Haemorrhagic condition, unspecified	0.001	0.555	0.445
L45 Papulosquamous disorders in diseases classified elsewhere	0.444	0.556	0.000
E00-E07 Disorders of thyroid gland	0.011	0.557	0.432
L41 Parapsoriasis	0.440	0.560	0.000
D61.0 Constitutional aplastic anaemia	0.000	0.561	0.439
D83.9 Common variable immunodeficiency, unspecified	0.000	0.565	0.435
M12.24 Villonodular synovitis (pigmented) (Hand)	0.432	0.568	0.000
J33.8 Other polyp of sinus	0.430	0.570	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.426	0.574	0.000
M11.28 Other chondrocalcinosis (Other)	0.426	0.574	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.426	0.574	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.426	0.574	0.000
M11.24 Other chondrocalcinosis (Hand)	0.426	0.574	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.426	0.574	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.426	0.574	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.426	0.574	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.574	0.425
E03.5 Myxoedema coma	0.355	0.575	0.070
E03.4 Atrophy of thyroid (acquired)	0.355	0.575	0.070
E03.3 Postinfectious hypothyroidism	0.355	0.575	0.070
D58 Other hereditary haemolytic anaemias	0.000	0.576	0.423
L43.8 Other lichen planus	0.421	0.579	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations