TreeWAS – Variant ID: rs4294134

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
S80 Superficial injury of lower leg	0.596	0.404
S82.10 Fracture of upper end of tibia (closed)	0.593	0.407
S80-S89 Injuries to the knee and lower leg	0.593	0.407
S80.9 Superficial injury of lower leg, unspecified	0.589	0.411
S82.1 Fracture of upper end of tibia	0.585	0.415
S82 Fracture of lower leg, including ankle	0.578	0.422
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.572	0.428
T36-T50 Poisoning by drugs, medicaments and biological substances	0.571	0.429
T20-T25 Burns and corrosions of external body surface, specified by site	0.560	0.440
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.548	0.452
T15-T19 Effects of foreign body entering through natural orifice	0.542	0.458
S82.0 Fracture of patella	0.534	0.466
S80.8 Other superficial injuries of lower leg	0.530	0.470
T66-T78 Other and unspecified effects of external causes	0.529	0.471
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.524	0.476
T17 Foreign body in respiratory tract	0.524	0.476
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.513	0.486
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.505	0.495
T17.2 Foreign body in pharynx	0.505	0.495
T78 Adverse effects, not elsewhere classified	0.505	0.495
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.503	0.497
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.502	0.498
S82.00 Fracture of patella (closed)	0.501	0.499
T78.4 Allergy, unspecified	0.493	0.507
T46 Poisoning by agents primarily affecting the cardiovascular system	0.490	0.510
T50.9 Other and unspecified drugs, medicaments and biological substances	0.487	0.513
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.484	0.516
S80.7 Multiple superficial injuries of lower leg	0.475	0.525
S89 Other and unspecified injuries of lower leg	0.473	0.527
T20 Burn and corrosion of head and neck	0.471	0.529
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.466	0.534
T31 Burns classified according to extent of body surface involved	0.462	0.537
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.461	0.539
T23 Burn and corrosion of wrist and hand	0.459	0.541
S82.11 Fracture of upper end of tibia (open)	0.456	0.544
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.455	0.545
T25 Burn and corrosion of ankle and foot	0.453	0.547
T42.4 Benzodiazepines	0.450	0.550
S80.1 Contusion of other and unspecified parts of lower leg	0.447	0.553
S80.0 Contusion of knee	0.445	0.555
T17.9 Foreign body in respiratory tract, part unspecified	0.439	0.561
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.436	0.564
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.434	0.566
T15 Foreign body on external eye	0.432	0.568
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.431	0.569
S84 Injury of nerves at lower leg level	0.431	0.569
S88 Traumatic amputation of lower leg	0.425	0.575
T42.1 Iminostilbenes	0.425	0.575
S85 Injury of blood vessels at lower leg level	0.423	0.576
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.422	0.578
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.420	0.580
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.420	0.580
T51 Toxic effect of alcohol	0.417	0.583
T54 Toxic effect of corrosive substances	0.414	0.586
T31.0 Burns involving less than 10% of body surface	0.411	0.589
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.410	0.589
T33-T35 Frostbite	0.410	0.590
T41 Poisoning by anaesthetics and therapeutic gases	0.409	0.591
T26-T28 Burns and corrosions confined to eye and internal organs	0.409	0.591
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.408	0.592
T50.1 Loop [high-ceiling] diuretics	0.408	0.592
S20-S29 Injuries to the thorax	0.408	0.592
S87 Crushing injury of lower leg	0.407	0.593
T47.1 Other antacids and anti-gastric-secretion drugs	0.405	0.595
T78.1 Other adverse food reactions, not elsewhere classified	0.401	0.599
T42.0 Hydantoin derivatives	0.400	0.600
T46.4 Angiotensin-converting-enzyme inhibitors	0.400	0.600
T17.8 Foreign body in other and multiple parts of respiratory tract	0.398	0.602
T78.8 Other adverse effects, not elsewhere classified	0.397	0.603
S82.2 Fracture of shaft of tibia	0.397	0.603
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.396	0.604
T66 Unspecified effects of radiation	0.395	0.605
T42.5 Mixed antiepileptics, not elsewhere classified	0.393	0.607
T42.2 Succinimides and oxazolidinediones	0.393	0.607
T50.4 Drugs affecting uric acid metabolism	0.390	0.610
T42.3 Barbiturates	0.390	0.610
S82.9 Fracture of lower leg, part unspecified	0.389	0.610
S82.01 Fracture of patella (open)	0.389	0.611
T29 Burns and corrosions of multiple body regions	0.389	0.611
T73 Effects of other deprivation	0.388	0.611
T23.3 Burn of third degree of wrist and hand	0.388	0.612
T18 Foreign body in alimentary tract	0.387	0.613
T56 Toxic effect of metals	0.387	0.613
T58 Toxic effect of carbon monoxide	0.387	0.613
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.386	0.614
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.382	0.618
T78.2 Anaphylactic shock, unspecified	0.381	0.619
S89.9 Unspecified injury of lower leg	0.381	0.619
T21 Burn and corrosion of trunk	0.380	0.620
T74 Maltreatment syndromes	0.379	0.621
T69 Other effects of reduced temperature	0.379	0.621
T67 Effects of heat and light	0.379	0.621
T68 Hypothermia	0.378	0.622
T30 Burn and corrosion, body region unspecified	0.377	0.623
T46.5 Other antihypertensive drugs, not elsewhere classified	0.377	0.623
T65 Toxic effect of other and unspecified substances	0.377	0.623
S10-S19 Injuries to the neck	0.376	0.624
T50.8 Diagnostic agents	0.376	0.624
T50.7 Analeptics and opioid receptor antagonists	0.376	0.624
T50.5 Appetite depressants	0.376	0.624
T50.3 Electrolytic, caloric and water-balance agents	0.376	0.624
T50.0 Mineralocorticoids and their antagonists	0.376	0.624
T17.4 Foreign body in trachea	0.376	0.624
T17.1 Foreign body in nostril	0.376	0.624
T17.0 Foreign body in nasal sinus	0.376	0.624
T20.1 Burn of first degree of head and neck	0.375	0.625
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.374	0.626
T51.9 Alcohol, unspecified	0.374	0.626
T55 Toxic effect of soaps and detergents	0.374	0.626
S22 Fracture of rib(s), sternum and thoracic spine	0.374	0.626
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.373	0.627
S82.7 Multiple fractures of lower leg	0.373	0.627
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.372	0.628
T52 Toxic effect of organic solvents	0.370	0.630
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.370	0.630
T46.3 Coronary vasodilators, not elsewhere classified	0.370	0.630
T37.8 Other specified systemic anti-infectives and antiparasitics	0.370	0.630
T25.0 Burn of unspecified degree of ankle and foot	0.369	0.631
T20.0 Burn of unspecified degree of head and neck	0.369	0.631
T16 Foreign body in ear	0.368	0.632
T62 Toxic effect of other noxious substances eaten as food	0.368	0.632
S86 Injury of muscle and tendon at lower leg level	0.367	0.633
T47.0 Histamine H(2)-receptor antagonists	0.367	0.633
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.366	0.634
T32 Corrosions classified according to extent of body surface involved	0.366	0.634
T36 Poisoning by systemic antibiotics	0.365	0.634
T75 Effects of other external causes	0.365	0.635
T78.9 Adverse effect, unspecified	0.364	0.636
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.363	0.637
T47.4 Other laxatives	0.362	0.637
S82.6 Fracture of lateral malleolus	0.362	0.638
T70 Effects of air pressure and water pressure	0.361	0.639
T61 Toxic effect of noxious substances eaten as seafood	0.361	0.639
T60 Toxic effect of pesticides	0.361	0.639
T57 Toxic effect of other inorganic substances	0.361	0.639
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.361	0.639
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.361	0.639
T79-T79 Certain early complications of trauma	0.361	0.639
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.360	0.640
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.360	0.640
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.360	0.640
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.360	0.640
T20.3 Burn of third degree of head and neck	0.357	0.643
T25.2 Burn of second degree of ankle and foot	0.357	0.643
T31.2 Burns involving 20-29% of body surface	0.356	0.644
T40.2 Other opioids	0.356	0.644
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.356	0.644
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.355	0.645
T40.1 Heroin	0.354	0.645
T46.1 Calcium-channel blockers	0.354	0.646
T47.6 Antidiarrhoeal drugs	0.354	0.646
T40.5 Cocaine	0.353	0.647
T46.8 Antivaricose drugs, including sclerosing agents	0.352	0.648
T46.7 Peripheral vasodilators	0.352	0.648
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.351	0.648
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.351	0.649
T17.3 Foreign body in larynx	0.350	0.649
T54.9 Corrosive substance, unspecified	0.350	0.650
T17.5 Foreign body in bronchus	0.349	0.651
T31.1 Burns involving 10-19% of body surface	0.348	0.652
S89.8 Other specified injuries of lower leg	0.348	0.652
R49.0 Dysphonia	0.348	0.652
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.347	0.653
T47.8 Other agents primarily affecting the gastro-intestinal system	0.347	0.653
T47.7 Emetics	0.347	0.653
T47.5 Digestants	0.347	0.653
T47.3 Saline and osmotic laxatives	0.347	0.653
T78.0 Anaphylactic shock due to adverse food reaction	0.347	0.653
T50.6 Antidotes and chelating agents, not elsewhere classified	0.346	0.654
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.345	0.654
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.345	0.655
T59 Toxic effect of other gases, fumes and vapours	0.343	0.657
T00-T07 Injuries involving multiple body regions	0.342	0.658
T71 Asphyxiation	0.341	0.659
S89.7 Multiple injuries of lower leg	0.339	0.661
S89.1 Other specified injuries of lower leg	0.339	0.661
S89.0 Multiple injuries of lower leg	0.339	0.661
T23.2 Burn of second degree of wrist and hand	0.339	0.661
T45.0 Antiallergic and antiemetic drugs	0.338	0.662
S22.3 Fracture of rib	0.338	0.662
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.338	0.662
T20.7 Corrosion of third degree of head and neck	0.337	0.662
T20.6 Corrosion of second degree of head and neck	0.337	0.662
T20.5 Corrosion of first degree of head and neck	0.337	0.662
T20.4 Corrosion of unspecified degree of head and neck	0.337	0.662
T13 Other injuries of lower limb, level unspecified	0.335	0.665
T45.2 Vitamins, not elsewhere classified	0.335	0.665
S83.6 Sprain and strain of other and unspecified parts of knee	0.335	0.665
T47.2 Stimulant laxatives	0.335	0.665
T20.2 Burn of second degree of head and neck	0.334	0.666
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.334	0.666
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.334	0.666
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.334	0.666
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.334	0.666
T40.6 Other and unspecified narcotics	0.332	0.668
T15.0 Foreign body in cornea	0.332	0.668
T31.9 Burns involving 90% or more of body surface	0.332	0.668
T31.8 Burns involving 80-89% of body surface	0.332	0.668
T31.7 Burns involving 70-79% of body surface	0.332	0.668
T31.6 Burns involving 60-69% of body surface	0.332	0.668
T31.5 Burns involving 50-59% of body surface	0.332	0.668
T31.4 Burns involving 40-49% of body surface	0.332	0.668
T31.3 Burns involving 30-39% of body surface	0.332	0.668
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.331	0.669
T40.8 Lysergide [LSD]	0.331	0.669
T40.7 Cannabis (derivatives)	0.331	0.669
T40.0 Opium	0.331	0.669
T23.7 Corrosion of third degree of wrist and hand	0.329	0.671
T23.6 Corrosion of second degree of wrist and hand	0.329	0.671
T23.5 Corrosion of first degree of wrist and hand	0.329	0.671
T23.4 Corrosion of unspecified degree of wrist and hand	0.329	0.671
T37.2 Antimalarials and drugs acting on other blood protozoa	0.329	0.671
T23.1 Burn of first degree of wrist and hand	0.329	0.671
S83.3 Tear of articular cartilage of knee, current	0.328	0.672
T40.4 Other synthetic narcotics	0.327	0.672
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.326	0.674
T37.5 Antiviral drugs	0.326	0.674
T37.4 Anthelminthics	0.326	0.674
T37.3 Other antiprotozoal drugs	0.326	0.674
T37.1 Antimycobacterial drugs	0.326	0.674
T37.0 Sulphonamides	0.326	0.674
T19 Foreign body in genito-urinary tract	0.325	0.674
T25.7 Corrosion of third degree of ankle and foot	0.325	0.675
T25.6 Corrosion of second degree of ankle and foot	0.325	0.675
T25.5 Corrosion of first degree of ankle and foot	0.325	0.675
T25.4 Corrosion of unspecified degree of ankle and foot	0.325	0.675
T25.1 Burn of first degree of ankle and foot	0.325	0.675
S90-S99 Injuries to the ankle and foot	0.325	0.675
T15.9 Foreign body on external eye, unspecified	0.324	0.676
S81 Open wound of lower leg	0.323	0.677
T15.1 Foreign body in conjunctival sac	0.323	0.677
T18.0 Foreign body in mouth	0.323	0.677
T45.4 Iron and its compounds	0.323	0.677
T40.3 Methadone	0.319	0.680
T39.0 Salicylates	0.319	0.681
T23.0 Burn of unspecified degree of wrist and hand	0.317	0.683
S22.5 Flail chest	0.317	0.683
S22.0 Fracture of thoracic vertebra	0.316	0.683
S84.1 Injury of peroneal nerve at lower leg level	0.315	0.685
S19 Other and unspecified injuries of neck	0.313	0.686
S22.30 Fracture of rib (closed)	0.313	0.687
S82.20 Fracture of shaft of tibia (closed)	0.313	0.687
T48.5 Anti-common-cold drugs	0.311	0.688
T08 Fracture of spine, level unspecified	0.312	0.688
T45.9 Primarily systemic and haematological agent, unspecified	0.311	0.688
T45.8 Other primarily systemic and haematological agents	0.311	0.688
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.311	0.688
T45.6 Fibrinolysis-affecting drugs	0.311	0.688
T45.3 Enzymes, not elsewhere classified	0.311	0.688
S12 Fracture of neck	0.311	0.689
T45.1 Antineoplastic and immunosuppressive drugs	0.310	0.690
T15.8 Foreign body in other and multiple parts of external eye	0.310	0.690
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.310	0.690
S84.9 Injury of unspecified nerve at lower leg level	0.309	0.691
S84.8 Injury of other nerves at lower leg level	0.309	0.691
S84.7 Injury of multiple nerves at lower leg level	0.309	0.691
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.309	0.691
S84.0 Injury of tibial nerve at lower leg level	0.309	0.691
T11 Other injuries of upper limb, level unspecified	0.307	0.693
S36 Injury of intra-abdominal organs	0.306	0.694
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.306	0.694
T18.9 Foreign body in alimentary tract, part unspecified	0.305	0.694
S88.9 Traumatic amputation of lower leg, level unspecified	0.305	0.695
S88.1 Traumatic amputation at level between knee and ankle	0.305	0.695
S88.0 Traumatic amputation at knee level	0.305	0.695
T14 Injury of unspecified body region	0.305	0.695
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.304	0.695
S85.9 Injury of unspecified blood vessel at lower leg level	0.304	0.696
S85.8 Injury of other blood vessels at lower leg level	0.304	0.696
S85.7 Injury of multiple blood vessels at lower leg level	0.304	0.696
S85.5 Injury of popliteal vein	0.304	0.696
S85.4 Injury of lesser saphenous vein at lower leg level	0.304	0.696
S85.3 Injury of greater saphenous vein at lower leg level	0.304	0.696
S85.2 Injury of peroneal artery	0.304	0.696
S85.0 Injury of popliteal artery	0.304	0.696
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.304	0.696
T56.8 Other metals	0.303	0.696
S82.5 Fracture of medial malleolus	0.303	0.697
T48.6 Antiasthmatics, not elsewhere classified	0.303	0.697
S85.1 Injury of (anterior)(posterior) tibial artery	0.302	0.698
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.301	0.698
T48.4 Expectorants	0.301	0.698
T48.3 Antitussives	0.301	0.698
T48.2 Other and unspecified agents primarily acting on muscles	0.301	0.698
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.301	0.698
T48.0 Oxytocic drugs	0.301	0.698
T12.X1 Fracture of lower limb, level unspecified (open)	0.301	0.699
T12.X0 Fracture of lower limb, level unspecified (closed)	0.301	0.699
T12 Fracture of lower limb, level unspecified	0.301	0.699
T10.X1 Fracture of upper limb, level unspecified (open)	0.301	0.699
T10.X0 Fracture of upper limb, level unspecified (closed)	0.301	0.699
T10 Fracture of upper limb, level unspecified	0.301	0.699
T08.X1 Fracture of spine, level unspecified (open)	0.301	0.699
T08.X0 Fracture of spine, level unspecified (closed)	0.301	0.699
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.300	0.700
S37 Injury of urinary and pelvic organs	0.300	0.700
S60-S69 Injuries to the wrist and hand	0.300	0.700
T51.8 Other alcohols	0.299	0.701
T51.3 Fusel oil	0.299	0.701
T51.2 2-Propanol	0.299	0.701
T51.1 Methanol	0.299	0.701
S82.61 Fracture of lateral malleolus (open)	0.299	0.701
T25.3 Burn of third degree of ankle and foot	0.298	0.702
S26 Injury of heart	0.298	0.702
T21.3 Burn of third degree of trunk	0.297	0.703
T54.3 Corrosive alkalis and alklali-like substances	0.297	0.703
T54.2 Corrosive acids and acid-like substances	0.297	0.703
T54.1 Other corrosive organic compounds	0.297	0.703
T54.0 Phenol and phenol homologues	0.297	0.703
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.296	0.704
S82.4 Fracture of fibula alone	0.296	0.704
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.296	0.704
T21.2 Burn of second degree of trunk	0.295	0.704
T49.9 Topical agent, unspecified	0.294	0.705
T49.8 Other topical agents	0.294	0.705
T49.7 Dental drugs, topically applied	0.294	0.705
T49.6 Otorhinolaryngological drugs and preparations	0.294	0.705
T49.5 Ophthalmological drugs and preparations	0.294	0.705
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.294	0.705
T49.3 Emollients, demulcents and protectants	0.294	0.705
T49.2 Local astringents and local detergents	0.294	0.705
T49.1 Antipruritics	0.294	0.705
T35 Frostbite involving multiple body regions and unspecified frostbite	0.294	0.706
T34 Frostbite with tissue necrosis	0.294	0.706
T33 Superficial frostbite	0.294	0.706
T41.5 Therapeutic gases	0.293	0.706
T41.4 Anaesthetic, unspecified	0.293	0.706
T41.3 Local anaesthetics	0.293	0.706
T41.2 Other and unspecified general anaesthetics	0.293	0.706
T41.1 Intravenous anaesthetics	0.293	0.706
T41.0 Inhaled anaesthetics	0.293	0.706
T28 Burn and corrosion of other internal organs	0.293	0.707
T27 Burn and corrosion of respiratory tract	0.293	0.707
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.293	0.707
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.292	0.708
S25 Injury of blood vessels of thorax	0.292	0.708
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.292	0.708
T26 Burn and corrosion confined to eye and adnexa	0.292	0.708
S87.0 Crushing injury of knee	0.292	0.708
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.291	0.709
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.291	0.709
S83.7 Injury to multiple structures of knee	0.291	0.709
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.290	0.709
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.289	0.711
S60 Superficial injury of wrist and hand	0.289	0.711
T29.0 Burns of multiple regions, unspecified degree	0.288	0.712
T73.3 Exhaustion due to excessive exertion	0.288	0.712
S31 Open wound of abdomen, lower back and pelvis	0.288	0.712
T65.9 Toxic effect of unspecified substance	0.286	0.714
S20 Superficial injury of thorax	0.285	0.715
S30 Superficial injury of abdomen, lower back and pelvis	0.285	0.715
T18.3 Foreign body in small intestine	0.283	0.716
S83.0 Dislocation of patella	0.282	0.718
S83.1 Dislocation of knee	0.282	0.718
T36.4 Tetracyclines	0.281	0.719
S82.91 Fracture of lower leg, part unspecified (open)	0.281	0.719
T30.0 Burn of unspecified body region, unspecified degree	0.280	0.720
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.279	0.721
T29.7 Corrosions of multiple regions, at least one corrosion of third degree mentioned	0.279	0.721
T29.6 Corrosions of multiple regions, no more than second-degree corrosions mentioned	0.279	0.721
T29.5 Corrosions of multiple regions, no more than first-degree corrosions mentioned	0.279	0.721
T29.4 Corrosions of multiple regions, unspecified degree	0.279	0.721
T29.2 Burns of multiple regions, no more than second-degree burns mentioned	0.279	0.721
T29.1 Burns of multiple regions, no more than first-degree burns mentioned	0.279	0.721
T73.9 Effect of deprivation, unspecified	0.279	0.721
T73.8 Other effects of deprivation	0.279	0.721
T73.2 Exhaustion due to exposure	0.279	0.721
T73.1 Effects of thirst	0.279	0.721
T73.0 Effects of hunger	0.279	0.721
T18.1 Foreign body in oesophagus	0.278	0.722
T18.8 Foreign body in other and multiple parts of alimentary tract	0.278	0.722
T18.4 Foreign body in colon	0.278	0.722
T56.9 Metal, unspecified	0.277	0.722
T56.7 Beryllium and its compounds	0.277	0.722
T56.6 Tin and its compounds	0.277	0.722
T56.5 Zinc and its compounds	0.277	0.722
T56.4 Copper and its compounds	0.277	0.722
T56.3 Cadmium and its compounds	0.277	0.722
T56.2 Chromium and its compounds	0.277	0.722
T56.1 Mercury and its compounds	0.277	0.722
T56.0 Lead and its compounds	0.277	0.722
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.277	0.723
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.277	0.723
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.277	0.723
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.277	0.723
T44.1 Other parasympathomimetics [cholinergics]	0.277	0.723
T44.0 Anticholinesterase agents	0.277	0.723
S67 Crushing injury of wrist and hand	0.276	0.723
S24 Injury of nerves and spinal cord at thorax level	0.276	0.724
S22.50 Flail chest (closed)	0.276	0.724
S22.00 Fracture of thoracic vertebra (closed)	0.276	0.724
S96 Injury of muscle and tendon at ankle and foot level	0.275	0.725
T52.8 Other organic solvents	0.275	0.725
T36.8 Other systemic antibiotics	0.274	0.725
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.274	0.725
S27 Injury of other and unspecified intrathoracic organs	0.274	0.726
T59.9 Gases, fumes and vapours, unspecified	0.274	0.726
S87.8 Crushing injury of other and unspecified parts of lower leg	0.273	0.727
T21.7 Corrosion of third degree of trunk	0.273	0.727
T21.6 Corrosion of second degree of trunk	0.273	0.727
T21.5 Corrosion of first degree of trunk	0.273	0.727
T21.4 Corrosion of unspecified degree of trunk	0.273	0.727
T67.9 Effects of heat and light, unspecified	0.272	0.728
T67.8 Other effects of heat and light	0.272	0.728
T67.7 Heat oedema	0.272	0.728
T67.6 Heat fatigue, transient	0.272	0.728
T67.5 Heat exhaustion, unspecified	0.272	0.728
T67.4 Heat exhaustion due to salt depletion	0.272	0.728
T67.3 Heat exhaustion, anhydrotic	0.272	0.728
T67.2 Heat cramp	0.272	0.728
T67.1 Heat syncope	0.272	0.728
T67.0 Heatstroke and sunstroke	0.272	0.728
T69.9 Effect of reduced temperature, unspecified	0.272	0.728
T69.8 Other specified effects of reduced temperature	0.272	0.728
T69.1 Chilblains	0.272	0.728
T69.0 Immersion hand and foot	0.272	0.728
T74.9 Maltreatment syndrome, unspecified	0.272	0.728
T74.8 Other maltreatment syndromes	0.272	0.728
T74.3 Psychological abuse	0.272	0.728
T74.2 Sexual abuse	0.272	0.728
T74.1 Physical abuse	0.272	0.728
T74.0 Neglect or abandonment	0.272	0.728
S19.8 Other specified injuries of neck	0.271	0.728
T62.9 Noxious substance eaten as food, unspecified	0.271	0.729
T30.7 Corrosion of third degree, body region unspecified	0.271	0.729
T30.6 Corrosion of second degree, body region unspecified	0.271	0.729
T30.5 Corrosion of first degree, body region unspecified	0.271	0.729
T30.4 Corrosion of unspecified body region, unspecified degree	0.271	0.729
T30.3 Burn of third degree, body region unspecified	0.271	0.729
T30.2 Burn of second degree, body region unspecified	0.271	0.729
T30.1 Burn of first degree, body region unspecified	0.271	0.729
T65.8 Toxic effect of other specified substances	0.270	0.730
T65.6 Paints and dyes, not elsewhere classified	0.270	0.730
T65.5 Nitroglycerin and other nitric acids and esters	0.270	0.730
T65.4 Carbon disulphide	0.270	0.730
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.270	0.730
T65.2 Tobacco and nicotine	0.270	0.730
T65.1 Strychnine and its salts	0.270	0.730
T65.0 Cyanides	0.270	0.730
S17 Crushing injury of neck	0.270	0.730
S15 Injury of blood vessels at neck level	0.270	0.730
S18 Traumatic amputation at neck level	0.270	0.730
S16 Injury of muscle and tendon at neck level	0.270	0.730
S22.1 Multiple fractures of thoracic spine	0.269	0.731
S22.9 Fracture of bony thorax, part unspecified	0.268	0.732
S22.8 Fracture of other parts of bony thorax	0.268	0.732
T75.4 Effects of electric current	0.268	0.732
S82.71 Multiple fractures of lower leg (open)	0.267	0.733
T39.4 Antirheumatics, not elsewhere classified	0.267	0.733
T39.2 Pyrazolone derivatives	0.267	0.733
S82.8 Fractures of other parts of lower leg	0.266	0.734
T13.0 Superficial injury of lower limb, level unspecified	0.266	0.734
T52.9 Organic solvent, unspecified	0.265	0.734
T52.4 Ketones	0.265	0.734
T52.3 Glycols	0.265	0.734
T52.2 Homologues of benzene	0.265	0.734
T52.1 Benzene	0.265	0.734
T52.0 Petroleum products	0.265	0.734
T45.5 Anticoagulants	0.265	0.735
T90 Sequelae of injuries of head	0.265	0.735
T62.8 Other specified noxious substances eaten as food	0.264	0.736
T62.2 Other ingested (parts of) plant(s)	0.264	0.736
T62.1 Ingested berries	0.264	0.736
T62.0 Ingested mushrooms	0.264	0.736
S86.0 Injury of Achilles tendon	0.263	0.737
S86.7 Injury of multiple muscles and tendons at lower leg level	0.263	0.737
T13.1 Open wound of lower limb, level unspecified	0.263	0.737
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.263	0.737
T32.9 Corrosions involving 90% or more of body surface	0.262	0.738
T32.8 Corrosions involving 80-89% of body surface	0.262	0.738
T32.7 Corrosions involving 70-79% of body surface	0.262	0.738
T32.6 Corrosions involving 60-69% of body surface	0.262	0.738
T32.5 Corrosions involving 50-59% of body surface	0.262	0.738
T32.4 Corrosions involving 40-49% of body surface	0.262	0.738
T32.3 Corrosions involving 30-39% of body surface	0.262	0.738
T32.2 Corrosions involving 20-29% of body surface	0.262	0.738
T32.1 Corrosions involving 10-19% of body surface	0.262	0.738
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.262	0.738
T36.9 Systemic antibiotic, unspecified	0.262	0.738
T36.7 Antifungal antibiotics, systemically used	0.262	0.738
T36.6 Rifamycins	0.262	0.738
T36.5 Aminoglycosides	0.262	0.738
T36.2 Chloramphenicol group	0.262	0.738
T75.8 Other specified effects of external causes	0.262	0.738
T75.3 Motion sickness	0.262	0.738
T75.2 Effects of vibration	0.262	0.738
T75.0 Effects of lightning	0.262	0.738
T63 Toxic effect of contact with venomous animals	0.261	0.738
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.261	0.739
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.260	0.740
T32.0 Corrosions involving less than 10% of body surface	0.260	0.740
T70.9 Effect of air pressure and water pressure, unspecified	0.259	0.741
T70.8 Other effects of air pressure and water pressure	0.259	0.741
T70.4 Effects of high-pressure fluids	0.259	0.741
T70.2 Other and unspecified effects of high altitude	0.259	0.741
T70.1 Sinus barotrauma	0.259	0.741
T70.0 Otitic barotrauma	0.259	0.741
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.259	0.741
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.259	0.741
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.259	0.741

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations