TreeWAS – Variant ID: rs4295627

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R94.3 Abnormal results of cardiovascular function studies	0.016	0.984	0.000
I86.1 Scrotal varices	0.014	0.986	0.000
R94 Abnormal results of function studies	0.014	0.986	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.014	0.986	0.000
R94.4 Abnormal results of kidney function studies	0.013	0.987	0.000
R94.5 Abnormal results of liver function studies	0.012	0.988	0.000
R94.0 Abnormal results of function studies of central nervous system	0.011	0.989	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.011	0.989	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.011	0.989	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.010	0.990	0.000
R94.7 Abnormal results of other endocrine function studies	0.010	0.990	0.000
R94.6 Abnormal results of thyroid function studies	0.010	0.990	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.009	0.991	0.000
I86 Varicose veins of other sites	0.009	0.991	0.000
D68.8 Other specified coagulation defects	0.009	0.991	0.000
R94.2 Abnormal results of pulmonary function studies	0.008	0.992	0.000
I80 Phlebitis and thrombophlebitis	0.008	0.992	0.000
D68 Other coagulation defects	0.007	0.993	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.007	0.993	0.000
I86.8 Varicose veins of other specified sites	0.007	0.993	0.000
I86.2 Pelvic varices	0.007	0.993	0.000
D68.9 Coagulation defect, unspecified	0.007	0.993	0.000
I86.3 Vulval varices	0.007	0.993	0.000
I86.0 Sublingual varices	0.007	0.993	0.000
D68.2 Hereditary deficiency of other clotting factors	0.007	0.993	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.007	0.993	0.000
I81 Portal vein thrombosis	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.006	0.994	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.006	0.994	0.000
F05.9 Delirium, unspecified	0.006	0.994	0.000
I87.1 Compression of vein	0.006	0.994	0.000
I87 Other disorders of veins	0.006	0.994	0.000
I82 Other venous embolism and thrombosis	0.006	0.994	0.000
D68.5 Primary Thrombophilia	0.006	0.994	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.006	0.994	0.000
D68.4 Acquired coagulation factor deficiency	0.005	0.994	0.000
D68.1 Hereditary factor XI deficiency	0.005	0.994	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.005	0.995	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.005	0.995	0.000
I82.2 Embolism and thrombosis of vena cava	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
F05.8 Other delirium	0.005	0.995	0.000
I82.3 Embolism and thrombosis of renal vein	0.005	0.995	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.005	0.995	0.000
M19.0 Primary arthrosis of other joints	0.005	0.995	0.000
I86.4 Gastric varices	0.005	0.995	0.000
O02.1 Missed abortion	0.000	0.995	0.005
I88 Nonspecific lymphadenitis	0.005	0.995	0.000
I87.9 Disorder of vein, unspecified	0.004	0.995	0.000
I87.0 Postphlebitic syndrome	0.004	0.995	0.000
F05.0 Delirium not superimposed on dementia, so described	0.004	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.004	0.995	0.000
I82.1 Thrombophlebitis migrans	0.004	0.995	0.000
I82.0 Budd-Chiari syndrome	0.004	0.995	0.000
I87.8 Other specified disorders of veins	0.004	0.996	0.000
K22.1 Ulcer of oesophagus	0.004	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.004	0.996	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.004	0.996	0.000
C91.1 Chronic lymphocytic leukaemia	0.004	0.996	0.000
I89.1 Lymphangitis	0.004	0.996	0.000
B07 Viral warts	0.000	0.996	0.004
M19.06 Primary arthrosis of other joints-Lower leg	0.004	0.996	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.004	0.996	0.000
M19.08 Primary arthrosis of other joints (Other)	0.004	0.996	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.004	0.996	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.996	0.000
G63.2 Diabetic polyneuropathy	0.004	0.996	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.004	0.996	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.004	0.996	0.000
I88.8 Other nonspecific lymphadenitis	0.003	0.996	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.003	0.996	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.003	0.996	0.000
F05.1 Delirium superimposed on dementia	0.003	0.996	0.000
I85 Oesophageal varices	0.003	0.996	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.996	0.004
F43.9 Reaction to severe stress, unspecified	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
F43.0 Acute stress reaction	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.997	0.003
F43.2 Adjustment disorders	0.003	0.997	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.003	0.997	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
S70.1 Contusion of thigh	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
O02 Other abnormal products of conception	0.000	0.997	0.003
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.997	0.003
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
C91 Lymphoid leukaemia	0.003	0.997	0.000
N76.4 Abscess of vulva	0.003	0.997	0.000
R23.4 Changes in skin texture	0.000	0.997	0.003
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.003	0.997	0.000
Z50.8 Care involving use of rehabilitation procedures	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
C91.4 Hairy-cell leukaemia	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
F43.8 Other reactions to severe stress	0.003	0.997	0.000
K22.5 Diverticulum of oesophagus, acquired	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.003	0.997	0.000
S71.1 Open wound of thigh	0.003	0.997	0.000
F03 Unspecified dementia	0.003	0.997	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.997	0.003
C71.1 Frontal lobe	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
C91.5 Adult T-cell leukaemia	0.002	0.998	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
C91.9 Lymphoid leukaemia, unspecified	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.002
O02.8 Other specified abnormal products of conception	0.000	0.998	0.002
N76 Other inflammation of vagina and vulva	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.998	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.002	0.998	0.000
C91.7 Other lymphoid leukaemia	0.002	0.998	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.002	0.998	0.000
C91.3 Prolymphocytic leukaemia	0.002	0.998	0.000
C91.2 Subacute lymphocytic leukaemia	0.002	0.998	0.000
H26.8 Other specified cataract	0.000	0.998	0.002
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.002	0.998	0.000
S71.0 Open wound of hip	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
I25.5 Ischaemic cardiomyopathy	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
F09 Unspecified organic or symptomatic mental disorder	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
S79.7 Multiple injuries of hip and thigh	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.998	0.000
K22.9 Disease of oesophagus, unspecified	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
N76.5 Ulceration of vagina	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
K22.4 Dyskinesia of oesophagus	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.002	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.1 Postencephalitic syndrome	0.002	0.998	0.000
F07.0 Organic personality disorder	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
K22 Other diseases of oesophagus	0.002	0.998	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.002
Z42.1 Follow-up care involving plastic surgery of breast	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
S72.7 Multiple fractures of femur	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.002
S74.9 Injury of unspecified nerve at hip and thigh level	0.001	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.001	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.001	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.001	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.001	0.998	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.001	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.001	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.001	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.001	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.001	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.001	0.998	0.000
S75.0 Injury of femoral artery	0.001	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.001	0.998	0.000
S77.1 Crushing injury of thigh	0.001	0.998	0.000
S77.0 Crushing injury of hip	0.001	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.001	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.001	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.001	0.998	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
R23 Other skin changes	0.000	0.998	0.002
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.998	0.000
F02.2 Dementia in Huntington's disease	0.001	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.001	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.001	0.998	0.000
F02.0 Dementia in Pick's disease	0.001	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
K22.3 Perforation of oesophagus	0.002	0.998	0.000
S73.1 Sprain and strain of hip	0.001	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.001	0.998	0.000
J31.0 Chronic rhinitis	0.002	0.998	0.000
Y04.8 Other specified place	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
F01 Vascular dementia	0.001	0.998	0.000
S76.1 Injury of quadriceps muscle and tendon	0.001	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.001	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.001	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.001	0.998	0.000
S76.0 Injury of muscle and tendon of hip	0.001	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.998	0.000
R23.0 Cyanosis	0.000	0.998	0.001
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.001	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.001	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.998	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.999	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.001	0.999	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.001	0.999	0.000
S72.1 Pertrochanteric fracture	0.001	0.999	0.000
S73.0 Dislocation of hip	0.001	0.999	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.999	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.999	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.999	0.001
L29.0 Pruritus ani	0.000	0.999	0.001
M89.88 Other specified disorders of bone (Other)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Z57.2 Occupational exposure to dust	0.000	0.999	0.001
C71 Malignant neoplasm of brain	0.001	0.999	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.001	0.999	0.000
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
S72.4 Fracture of lower end of femur	0.001	0.999	0.000
M89 Other disorders of bone	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.001	0.999	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.999	0.000
F01.8 Other vascular dementia	0.001	0.999	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.999	0.000
F01.2 Subcortical vascular dementia	0.001	0.999	0.000
F01.1 Multi-infarct dementia	0.001	0.999	0.000
F01.0 Vascular dementia of acute onset	0.001	0.999	0.000
K09.0 Developmental odontogenic cysts	0.001	0.999	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
M84.8 Other disorders of continuity of bone	0.001	0.999	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
M84.2 Delayed union of fracture	0.001	0.999	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
C71.4 Occipital lobe	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.999	0.000
F06.5 Organic dissociative disorder	0.001	0.999	0.000
F06.4 Organic anxiety disorder	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.999	0.000
F06.1 Organic catatonic disorder	0.001	0.999	0.000
F06.0 Organic hallucinosis	0.001	0.999	0.000
G25.3 Myoclonus	0.001	0.999	0.000
Y41.1 Antimycobacterial drugs	0.001	0.999	0.000
L43 Lichen planus	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.999	0.000
C71.3 Parietal lobe	0.001	0.999	0.000
N75.1 Abscess of Bartholin's gland	0.001	0.999	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.001	0.999	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.001	0.999	0.000
S11.9 Open wound of neck, part unspecified	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
D21.9 Connective and other soft tissue, unspecified	0.001	0.999	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.999	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.999	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.999	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
C67.2 Lateral wall of bladder	0.000	0.999	0.001
C71.7 Brain stem	0.001	0.999	0.000
C71.6 Cerebellum	0.001	0.999	0.000
C71.5 Cerebral ventricle	0.001	0.999	0.000
N19 Unspecified renal failure	0.001	0.999	0.000
N75 Diseases of Bartholin's gland	0.001	0.999	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M89.6 Osteopathy after poliomyelitis	0.001	0.999	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.999	0.000
M89.3 Hypertrophy of bone	0.001	0.999	0.000
M89.2 Other disorders of bone development and growth	0.001	0.999	0.000
M89.1 Epiphyseal arrest	0.001	0.999	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.999	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.999	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.999	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.999	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.999	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.999	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.999	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.999	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.999	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.999	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.999	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.999	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.999	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.999	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.999	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.000	0.999	0.001
M50.2 Other cervical disk displacement	0.001	0.999	0.000
R40.0 Somnolence	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.999	0.000
F60 Specific personality disorders	0.000	0.999	0.001
K13 Other diseases of lip and oral mucosa	0.000	0.999	0.001
M54.92 Dorsalgia, unspecified (Cervical region)	0.001	0.999	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
C67.4 Posterior wall of bladder	0.000	0.999	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.999	0.001
C82.0 Small cleaved cell, follicular	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.001	0.999	0.000
G93.6 Cerebral oedema	0.000	0.999	0.001
L43.3 Subacute (active) lichen planus	0.001	0.999	0.000
L43.2 Lichenoid drug reaction	0.001	0.999	0.000
L43.1 Bullous lichen planus	0.001	0.999	0.000
L43.0 Hypertrophic lichen planus	0.001	0.999	0.000
M89.5 Osteolysis	0.001	0.999	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.001	0.999	0.000
D24 Benign neoplasm of breast	0.000	0.999	0.001
M89.38 Hypertrophy of bone (Other)	0.001	0.999	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
F60.9 Personality disorder, unspecified	0.000	0.999	0.001
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
Y41.0 Sulphonamides	0.001	0.999	0.000
Y58.0 BCG vaccine	0.001	0.999	0.000
M54.57 Low back pain (Lumbosacral region)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.999	0.001
K11.2 Sialoadenitis	0.001	0.999	0.000
R23.1 Pallor	0.000	0.999	0.001
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.001	0.999	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.999	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
H92.1 Otorrhoea	0.001	0.999	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.001	0.999	0.000
N75.8 Other diseases of Bartholin's gland	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.999	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations