TreeWAS – Variant ID: rs4308217

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E22.0 Acromegaly and pituitary gigantism	0.123	0.877	0.000
E22 Hyperfunction of pituitary gland	0.123	0.877	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.122	0.878	0.000
E22.1 Hyperprolactinaemia	0.114	0.886	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.088	0.912	0.000
E22.8 Other hyperfunction of pituitary gland	0.088	0.912	0.000
E24 Cushing's syndrome	0.044	0.956	0.000
E20-E35 Disorders of other endocrine glands	0.044	0.956	0.000
E24.9 Cushing's syndrome, unspecified	0.042	0.958	0.000
O90 Complications of the puerperium, not elsewhere classified	0.040	0.960	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.040	0.960	0.000
E24.0 Pituitary-dependent Cushing's disease	0.037	0.963	0.000
E24.2 Drug-induced Cushing's syndrome	0.037	0.963	0.000
O90.9 Complication of the puerperium, unspecified	0.035	0.965	0.000
O90.2 Haematoma of obstetric wound	0.035	0.965	0.000
O86.4 Pyrexia of unknown origin following delivery	0.035	0.965	0.000
O85-O92 Complications predominantly related to the puerperium	0.034	0.966	0.000
O86 Other puerperal infections	0.034	0.966	0.000
O90.0 Disruption of Caesarean section wound	0.034	0.966	0.000
E34 Other endocrine disorders	0.033	0.966	0.000
E28 Ovarian dysfunction	0.033	0.967	0.000
E24.8 Other Cushing's syndrome	0.033	0.967	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.032	0.968	0.000
E24.3 Ectopic ACTH syndrome	0.032	0.968	0.000
E24.1 Nelson's syndrome	0.032	0.968	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.032	0.968	0.000
E32 Diseases of thymus	0.032	0.968	0.000
E31 Polyglandular dysfunction	0.032	0.968	0.000
E30 Disorders of puberty, not elsewhere classified	0.032	0.968	0.000
E23 Hypofunction and other disorders of pituitary gland	0.030	0.970	0.000
O91 Infections of breast associated with childbirth	0.030	0.970	0.000
O90.5 Postpartum thyroiditis	0.029	0.971	0.000
O90.4 Postpartum acute renal failure	0.029	0.971	0.000
O90.3 Cardiomyopathy in the puerperium	0.029	0.971	0.000
E25 Adrenogenital disorders	0.029	0.971	0.000
O86.2 Urinary tract infection following delivery	0.029	0.971	0.000
O90.1 Disruption of perineal obstetric wound	0.029	0.971	0.000
E28.2 Polycystic ovarian syndrome	0.028	0.972	0.000
E34.0 Carcinoid syndrome	0.027	0.972	0.000
E20 Hypoparathyroidism	0.027	0.973	0.000
E26 Hyperaldosteronism	0.027	0.973	0.000
E34.9 Endocrine disorder, unspecified	0.026	0.974	0.000
O86.1 Other infection of genital tract following delivery	0.025	0.974	0.000
E34.3 Short stature, not elsewhere classified	0.025	0.975	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.025	0.975	0.000
E29 Testicular dysfunction	0.025	0.975	0.000
O88 Obstetric embolism	0.025	0.975	0.000
O86.8 Other specified puerperal infections	0.025	0.975	0.000
O86.3 Other genito-urinary tract infections following delivery	0.025	0.975	0.000
O91.1 Abscess of breast associated with childbirth	0.024	0.975	0.000
E34.5 Androgen resistance syndrome	0.024	0.976	0.000
E34.4 Constitutional tall stature	0.024	0.976	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.024	0.976	0.000
E34.1 Other hypersecretion of intestinal hormones	0.024	0.976	0.000
E28.9 Ovarian dysfunction, unspecified	0.024	0.976	0.000
E28.8 Other ovarian dysfunction	0.024	0.976	0.000
E28.1 Androgen excess	0.024	0.976	0.000
E28.0 Oestrogen excess	0.024	0.976	0.000
E27 Other disorders of adrenal gland	0.024	0.976	0.000
O85 Puerperal sepsis	0.024	0.976	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.023	0.977	0.000
E30.9 Disorder of puberty, unspecified	0.023	0.977	0.000
E30.8 Other disorders of puberty	0.023	0.977	0.000
E30.1 Precocious puberty	0.023	0.977	0.000
E30.0 Delayed puberty	0.023	0.977	0.000
E31.9 Polyglandular dysfunction, unspecified	0.023	0.977	0.000
E31.8 Other polyglandular dysfunction	0.023	0.977	0.000
E31.1 Polyglandular hyperfunction	0.023	0.977	0.000
E31.0 Autoimmune polyglandular failure	0.023	0.977	0.000
E32.9 Disease of thymus, unspecified	0.023	0.977	0.000
E32.8 Other diseases of thymus	0.023	0.977	0.000
E32.1 Abscess of thymus	0.023	0.977	0.000
E32.0 Persistent hyperplasia of thymus	0.023	0.977	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.023	0.977	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.023	0.977	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.023	0.977	0.000
O89 Complications of anaesthesia during the puerperium	0.022	0.977	0.000
E23.0 Hypopituitarism	0.022	0.978	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.022	0.978	0.000
E23.1 Drug-induced hypopituitarism	0.022	0.978	0.000
O87 Venous complications in the puerperium	0.022	0.978	0.000
O91.0 Infection of nipple associated with childbirth	0.021	0.978	0.000
E23.2 Diabetes insipidus	0.022	0.978	0.000
E23.7 Disorder of pituitary gland, unspecified	0.021	0.979	0.000
E25.9 Adrenogenital disorder, unspecified	0.021	0.979	0.000
E25.8 Other adrenogenital disorders	0.021	0.979	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.021	0.979	0.000
E20.8 Other hypoparathyroidism	0.020	0.980	0.000
E20.1 Pseudohypoparathyroidism	0.020	0.980	0.000
E20.0 Idiopathic hypoparathyroidism	0.020	0.980	0.000
E28.3 Primary ovarian failure	0.020	0.980	0.000
E26.8 Other hyperaldosteronism	0.019	0.980	0.000
E26.1 Secondary hyperaldosteronism	0.019	0.980	0.000
E23.6 Other disorders of pituitary gland	0.019	0.981	0.000
E27.8 Other specified disorders of adrenal gland	0.019	0.981	0.000
E34.8 Other specified endocrine disorders	0.018	0.981	0.000
G35 Multiple sclerosis	0.000	0.981	0.019
E26.9 Hyperaldosteronism, unspecified	0.018	0.982	0.000
E29.9 Testicular dysfunction, unspecified	0.018	0.982	0.000
E29.8 Other testicular dysfunction	0.018	0.982	0.000
E29.0 Testicular hyperfunction	0.018	0.982	0.000
O88.8 Other obstetric embolism	0.018	0.982	0.000
O88.3 Obstetric pyaemic and septic embolism	0.018	0.982	0.000
O88.2 Obstetric blood-clot embolism	0.018	0.982	0.000
O88.1 Amniotic fluid embolism	0.018	0.982	0.000
O88.0 Obstetric air embolism	0.018	0.982	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.018	0.982	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.018	0.982	0.000
E27.2 Addisonian crisis	0.018	0.982	0.000
E27.5 Adrenomedullary hyperfunction	0.017	0.983	0.000
E27.0 Other adrenocortical overactivity	0.017	0.983	0.000
O92.7 Other and unspecified disorders of lactation	0.017	0.983	0.000
O92.6 Galactorrhoea	0.017	0.983	0.000
O92.5 Suppressed lactation	0.017	0.983	0.000
O92.4 Hypogalactia	0.017	0.983	0.000
O92.3 Agalactia	0.017	0.983	0.000
O92.0 Retracted nipple associated with childbirth	0.017	0.983	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.017	0.983	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.017	0.983	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.016	0.984	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.016	0.984	0.000
O89.6 Failed or difficult intubation during the puerperium	0.016	0.984	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.016	0.984	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.016	0.984	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.016	0.984	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.016	0.984	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.016	0.984	0.000
E26.0 Primary hyperaldosteronism	0.016	0.984	0.000
O87.9 Venous complication in the puerperium, unspecified	0.016	0.984	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.016	0.984	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.016	0.984	0.000
O86.0 Infection of obstetric surgical wound	0.016	0.984	0.000
O92.1 Cracked nipple associated with childbirth	0.016	0.984	0.000
O87.2 Haemorrhoids in the puerperium	0.015	0.985	0.000
E20.9 Hypoparathyroidism, unspecified	0.015	0.985	0.000
O87.8 Other venous complications in the puerperium	0.015	0.985	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.014	0.986	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.014	0.986	0.000
E21.4 Other specified disorders of parathyroid gland	0.014	0.986	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.013	0.987	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.987	0.013
G37 Other demyelinating diseases of central nervous system	0.000	0.988	0.012
M25.6 Stiffness of joint, not elsewhere classified	0.012	0.988	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.012	0.988	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.012	0.988	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.988	0.012
E21.2 Other hyperparathyroidism	0.011	0.988	0.000
E21.0 Primary hyperparathyroidism	0.011	0.989	0.000
C62.9 Testis, unspecified	0.000	0.989	0.011
E29.1 Testicular hypofunction	0.011	0.989	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.011	0.989	0.000
Z99.2 Dependence on renal dialysis	0.011	0.989	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.010	0.989	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.989	0.010
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.010	0.990	0.000
H02.4 Ptosis of eyelid	0.010	0.990	0.000
G36 Other acute disseminated demyelination	0.000	0.991	0.009
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.009	0.991	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.991	0.009
G37.4 Subacute necrotising myelitis	0.000	0.991	0.009
G37.2 Central pontine myelinolysis	0.000	0.991	0.009
G37.1 Central demyelination of corpus callosum	0.000	0.991	0.009
G37.0 Diffuse sclerosis	0.000	0.991	0.009
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.009	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.009	0.991	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.009	0.991	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.009	0.991	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.008	0.992	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.992	0.008
Q21.1 Atrial septal defect	0.008	0.992	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.008	0.992	0.000
D37.7 Other digestive organs	0.000	0.992	0.008
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.993	0.002
G36.9 Acute disseminated demyelination, unspecified	0.000	0.993	0.007
G36.8 Other specified acute disseminated demyelination	0.000	0.993	0.007
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.993	0.007
G36.0 Neuromyelitis optica [Devic]	0.000	0.993	0.007
Q21.0 Ventricular septal defect	0.006	0.994	0.000
H40.9 Glaucoma, unspecified	0.000	0.994	0.006
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.994	0.006
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
C62 Malignant neoplasm of testis	0.000	0.995	0.005
C81.9 Hodgkin's disease, unspecified	0.000	0.995	0.005
O36.8 Maternal care for other specified foetal problems	0.000	0.995	0.005
H21.8 Other specified disorders of iris and ciliary body	0.000	0.995	0.005
C81 Hodgkin's disease	0.000	0.995	0.005
H17.9 Corneal scar and opacity, unspecified	0.000	0.995	0.005
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.996	0.004
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
C62.1 Descended testis	0.000	0.996	0.004
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Y85.0 Sequelae of motor-vehicle accident	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
C81.0 Lymphocytic predominance	0.000	0.996	0.004
C62.0 Undescended testis	0.000	0.996	0.004
C81.1 Nodular sclerosis	0.000	0.996	0.004
C81.2 Mixed cellularity	0.000	0.996	0.004
H20.8 Other iridocyclitis	0.000	0.996	0.004
H17 Corneal scars and opacities	0.000	0.996	0.004
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
H20 Iridocyclitis	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.000	0.996	0.004
E21.3 Hyperparathyroidism, unspecified	0.003	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
Q27.3 Peripheral arteriovenous malformation	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.996	0.004
H21 Other disorders of iris and ciliary body	0.000	0.996	0.004
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.996	0.004
Q25.1 Coarctation of aorta	0.003	0.996	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.996	0.003
C81.3 Lymphocytic depletion	0.000	0.996	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.004	0.996	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.996	0.004
H20.0 Acute and subacute iridocyclitis	0.000	0.996	0.003
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.997	0.003
C81.7 Other Hodgkin's disease	0.000	0.997	0.003
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
C84.0 Mycosis fungoides	0.000	0.997	0.003
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.997	0.003
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
C50.4 Upper-outer quadrant of breast	0.003	0.997	0.000
D37.2 Small intestine	0.000	0.997	0.003
H17.1 Other central corneal opacity	0.000	0.997	0.003
H17.0 Adherent leukoma	0.000	0.997	0.003
H20.1 Chronic iridocyclitis	0.000	0.997	0.003
C74.9 Adrenal gland, unspecified	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.000	0.997	0.003
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
Q24 Other congenital malformations of heart	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.003
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.997	0.003
O69.9 Labour and delivery complicated by cord complication, unspecified	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.997	0.003
D37.6 Liver, gallbladder and bile ducts	0.000	0.997	0.003
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
C82.2 Large cell, follicular	0.000	0.997	0.003
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.997	0.003
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.997	0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.997	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
H16 Keratitis	0.000	0.997	0.003
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.997	0.003
I08 Multiple valve diseases	0.000	0.997	0.003
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.997	0.003
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.997	0.003
H21.4 Pupillary membranes	0.000	0.997	0.003
H20.9 Iridocyclitis, unspecified	0.000	0.997	0.003
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.997	0.003
Q25.6 Stenosis of pulmonary artery	0.002	0.997	0.000
C93 Monocytic leukaemia	0.000	0.997	0.003
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.997	0.003
C88 Malignant immunoproliferative diseases	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Z35 Supervision of high-risk pregnancy	0.003	0.997	0.000
C86 Other specified types of T/NK-cell lymphoma	0.000	0.997	0.003
H16.9 Keratitis, unspecified	0.000	0.997	0.003
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
O69.8 Labour and delivery complicated by other cord complications	0.003	0.997	0.000
C95 Leukaemia of unspecified cell type	0.000	0.997	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.997	0.003
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.997	0.002
K10.8 Other specified diseases of jaws	0.000	0.997	0.003
D37.3 Appendix	0.000	0.997	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.997	0.002
Z35.5 Supervision of elderly primigravida	0.002	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
C94 Other leukaemias of specified cell type	0.000	0.998	0.002
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.998	0.002
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.998	0.002
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.998	0.002
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.998	0.002
C84.3 Lymphoepithelioid lymphoma	0.000	0.998	0.002
C84.2 T-zone lymphoma	0.000	0.998	0.002
C84.1 Sezary's diease	0.000	0.998	0.002
C93.1 Chronic monocytic leukaemia	0.000	0.998	0.002
H21.0 Hyphaema	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.998	0.002
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.998	0.002
C85.0 Lymphosarcoma	0.000	0.998	0.002
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.998	0.002
H16.8 Other keratitis	0.000	0.998	0.002
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.002
C82.6 Cutaneous follicle centre lymphoma	0.000	0.998	0.002
C82.5 Diffuse follicle centre lymphoma	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
C95.9 Leukaemia, unspecified	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.000	0.998	0.002
H16.3 Interstitial and deep keratitis	0.000	0.998	0.002
M47.2 Other spondylosis with radiculopathy	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.998	0.002
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.998	0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
W10.8 Other specified place	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.002
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.998	0.002
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.000	0.998	0.002
C93.9 Monocytic leukaemia, unspecified	0.000	0.998	0.002
C93.7 Other monocytic leukaemia	0.000	0.998	0.002
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.998	0.002
C93.2 Subacute monocytic leukaemia	0.000	0.998	0.002
C93.0 Acute monocytic leukaemia	0.000	0.998	0.002
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.998	0.002
C88.7 Other malignant immunoproliferative diseases	0.000	0.998	0.002
C88.3 Immunoproliferative small intestinal disease	0.000	0.998	0.002
C88.2 Gamma heavy chain disease	0.000	0.998	0.002
C88.1 Alpha heavy chain disease	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.002	0.998	0.000
Z35.6 Supervision of very young primigravida	0.002	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.998	0.002
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.998	0.002
C86.4 Blastic NK-cell lymphoma	0.000	0.998	0.002
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.998	0.002
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.998	0.002
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.998	0.002
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.998	0.002
C45 Mesothelioma	0.000	0.998	0.002
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.998	0.002
K11.2 Sialoadenitis	0.000	0.998	0.002
H15 Disorders of sclera	0.000	0.998	0.002
C82.4 Follicular lymphoma grade IIIb	0.000	0.998	0.002
R07.2 Precordial pain	0.000	0.998	0.002
C95.7 Other leukaemia of unspecified cell type	0.000	0.998	0.002
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.998	0.002
C94.7 Other specified leukaemias	0.000	0.998	0.002
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.998	0.002
C94.5 Acute myelofibrosis	0.000	0.998	0.002
C94.4 Acute panmyelosis	0.000	0.998	0.002
C94.3 Mast cell leukaemia	0.000	0.998	0.002
C94.2 Acute megakaryoblastic leukaemia	0.000	0.998	0.002
C94.1 Chronic erythraemia	0.000	0.998	0.002
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.998	0.002
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
C96.8 Histiocytic sarcoma	0.000	0.998	0.002
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.998	0.002
C96.3 True histiocytic lymphoma	0.000	0.998	0.002
C96.2 Malignant mast cell tumour	0.000	0.998	0.002
C96.1 Malignant histiocytosis	0.000	0.998	0.002
C96.0 Letterer-Siwe disease	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.000	0.998	0.002
C95.0 Acute leukaemia of unspecified cell type	0.000	0.998	0.002
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
C83.7 Burkitt's tumour	0.000	0.998	0.002
Y85 Sequelae of transport accidents	0.002	0.998	0.000
D37.5 Rectum	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
C74 Malignant neoplasm of adrenal gland	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C45.2 Mesothelioma of pericardium	0.000	0.998	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.002	0.998	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.998	0.002
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
H15.0 Scleritis	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
C91 Lymphoid leukaemia	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.998	0.002
D37.1 Stomach	0.000	0.998	0.002
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
H15.9 Disorder of sclera, unspecified	0.000	0.998	0.001
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.000	0.998	0.001
H15.1 Episcleritis	0.000	0.998	0.001
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.001	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.002
C74.0 Cortex of adrenal gland	0.001	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.998	0.002
O69.5 Labour and delivery complicated by vascular lesion of cord	0.001	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.001	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.001	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.001
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.998	0.001
C91.7 Other lymphoid leukaemia	0.000	0.998	0.001
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations