TreeWAS – Variant ID: rs4384548

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	No effect posterior probability	Protective posterior probability
O60-O75 Complications of labour and delivery	0.006	0.994
Chapter XV Pregnancy, childbirth and the puerperium	0.008	0.992
O70 Perineal laceration during delivery	0.036	0.964
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.039	0.961
O63 Long labour	0.040	0.960
O70.0 First degree perineal laceration during delivery	0.042	0.958
O80-O84 Delivery	0.055	0.945
O72 Postpartum haemorrhage	0.057	0.943
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.080	0.920
O36 Maternal care for other known or suspected foetal problems	0.083	0.917
O42 Premature rupture of membranes	0.094	0.906
O82 Single delivery by Caesarean section	0.142	0.858
O69 Labour and delivery complicated by umbilical cord complications	0.142	0.858
O42.9 Premature rupture of membranes, unspecified	0.145	0.855
O63.0 Prolonged first stage (of labour)	0.146	0.854
O20-O29 Other maternal disorders predominantly related to pregnancy	0.161	0.839
O63.9 Long labour, unspecified	0.164	0.836
O80 Single spontaneous delivery	0.167	0.833
O72.2 Delayed and secondary postpartum haemorrhage	0.172	0.828
O63.1 Prolonged second stage (of labour)	0.175	0.825
O16 Unspecified maternal hypertension	0.186	0.814
O72.1 Other immediate postpartum haemorrhage	0.193	0.807
O62 Abnormalities of forces of labour	0.210	0.790
O36.5 Maternal care for poor foetal growth	0.215	0.785
O00-O08 Pregnancy with abortive outcome	0.215	0.785
O82.0 Delivery by elective Caesarean section	0.222	0.778
O94-O99 Other obstetric conditions, not elsewhere classified	0.224	0.776
O72.0 Third-stage haemorrhage	0.225	0.775
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.226	0.774
O36.8 Maternal care for other specified foetal problems	0.234	0.766
O66 Other obstructed labour	0.234	0.765
O80.0 Spontaneous vertex delivery	0.235	0.765
O46 Antepartum haemorrhage, not elsewhere classified	0.235	0.765
O61 Failed induction of labour	0.245	0.755
O65 Obstructed labour due to maternal pelvic abnormality	0.245	0.755
O75 Other complications of labour and delivery, not elsewhere classified	0.246	0.754
O36.0 Maternal care for rhesus isoimmunisation	0.247	0.753
O43 Placental disorders	0.250	0.750
O85-O92 Complications predominantly related to the puerperium	0.257	0.743
O73 Retained placenta and membranes, without haemorrhage	0.265	0.735
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.267	0.733
O64 Obstructed labour due to malposition and malpresentation of foetus	0.270	0.730
O71 Other obstetric trauma	0.273	0.727
O69.1 Labour and delivery complicated by cord around neck, with compression	0.282	0.717
O44 Placenta praevia	0.283	0.717
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.285	0.715
O60 Preterm delivery	0.287	0.713
O70.9 Perineal laceration during delivery, unspecified	0.289	0.711
O81 Single delivery by forceps and vacuum extractor	0.292	0.708
O36.6 Maternal care for excessive foetal growth	0.293	0.707
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.296	0.704
O70.3 Fourth degree perineal laceration during delivery	0.297	0.703
O21 Excessive vomiting in pregnancy	0.297	0.703
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.300	0.700
O41 Other disorders of amniotic fluid and membranes	0.303	0.697
O35 Maternal care for known or suspected foetal abnormality and damage	0.306	0.694
O74 Complications of anaesthesia during labour and delivery	0.307	0.692
O47 False labour	0.309	0.691
O63.2 Delayed delivery of second twin, triplet, etc.	0.311	0.688
O82.9 Delivery by Caesarean section, unspecified	0.318	0.682
O36.3 Maternal care for signs of foetal hypoxia	0.318	0.681
O36.9 Maternal care for foetal problem, unspecified	0.322	0.678
O03 Spontaneous abortion	0.323	0.677
O45 Premature separation of placenta [abruptio placentae]	0.323	0.676
O72.3 Postpartum coagulation defects	0.324	0.676
O83 Other assisted single delivery	0.328	0.672
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.328	0.672
O84 Multiple delivery	0.329	0.671
O33 Maternal care for known or suspected disproportion	0.330	0.669
O68 Labour and delivery complicated by foetal stress [distress]	0.333	0.667
O31 Complications specific to multiple gestation	0.336	0.664
O69.2 Labour and delivery complicated by other cord entanglement	0.342	0.657
O15 Eclampsia	0.345	0.655
O30 Multiple gestation	0.348	0.652
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.349	0.651
O36.2 Maternal care for hydrops foetalis	0.350	0.650
O20 Haemorrhage in early pregnancy	0.351	0.649
O36.4 Maternal care for intra-uterine death	0.353	0.647
O69.8 Labour and delivery complicated by other cord complications	0.354	0.646
O36.1 Maternal care for other isoimmunisation	0.363	0.637
O69.0 Labour and delivery complicated by prolapse of cord	0.364	0.636
O42.2 Premature rupture of membranes, labour delayed by therapy	0.365	0.634
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.368	0.632
O26 Maternal care for other conditions predominantly related to pregnancy	0.368	0.632
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.369	0.631
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.369	0.631
O80.8 Other single spontaneous delivery	0.372	0.628
O02 Other abnormal products of conception	0.373	0.627
O23 Infections of genito-urinary tract in pregnancy	0.376	0.624
O62.2 Other uterine inertia	0.382	0.618
O48 Prolonged pregnancy	0.382	0.617
O82.8 Other single delivery by Caesarean section	0.384	0.615
O82.2 Delivery by Caesarean hysterectomy	0.384	0.615
O69.5 Labour and delivery complicated by vascular lesion of cord	0.385	0.615
O69.4 Labour and delivery complicated by vasa praevia	0.385	0.615
O69.3 Labour and delivery complicated by short cord	0.385	0.615
O46.8 Other antepartum haemorrhage	0.386	0.614
O40 Polyhydramnios	0.387	0.612
O62.3 Precipitate labour	0.396	0.604
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.398	0.602
O29 Complications of anaesthesia during pregnancy	0.398	0.601
O25 Malnutrition in pregnancy	0.398	0.601
O28 Abnormal findings on antenatal screening of mother	0.399	0.601
O82.1 Delivery by emergency Caesarean section	0.401	0.599
O69.9 Labour and delivery complicated by cord complication, unspecified	0.401	0.599
O80.1 Spontaneous breech delivery	0.403	0.597
O66.4 Failed trial of labour, unspecified	0.408	0.592
O61.1 Failed instrumental induction of labour	0.411	0.589
O22 Venous complications in pregnancy	0.413	0.587
O01 Hydatidiform mole	0.414	0.585
O85 Puerperal sepsis	0.415	0.585
O70.2 Third degree perineal laceration during delivery	0.415	0.584
O43.8 Other placental disorders	0.417	0.583
O66.0 Obstructed labour due to shoulder dystocia	0.418	0.582
O66.2 Obstructed labour due to unusually large foetus	0.419	0.581
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.420	0.580
O03.9 Complete or unspecified, without complication	0.420	0.580
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.420	0.580
O62.1 Secondary uterine inertia	0.426	0.574
O62.0 Primary inadequate contractions	0.426	0.574
O14.0 Moderate preeclampsia	0.427	0.573
O81.4 Vacuum extractor delivery	0.430	0.570
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.430	0.569
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.433	0.567
O43.9 Placental disorder, unspecified	0.434	0.566
O73.0 Retained placenta, without haemorrhage	0.435	0.565
O46.9 Antepartum haemorrhage, unspecified	0.437	0.563
O05 Other abortion	0.437	0.563
O62.8 Other abnormalities of forces of labour	0.439	0.560
O75.8 Other specified complications of labour and delivery	0.439	0.560
O07 Failed attempted abortion	0.441	0.558
O87 Venous complications in the puerperium	0.441	0.558
O21.0 Mild hyperemesis gravidarum	0.443	0.557
O97 Death from sequelae of direct obstetric causes	0.444	0.556
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.444	0.556
O95 Obstetric death of unspecified cause	0.444	0.556
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.444	0.556
O21.9 Vomiting of pregnancy, unspecified	0.446	0.554
O75.5 Delayed delivery after artificial rupture of membranes	0.446	0.554
O75.3 Other infection during labour	0.447	0.553
O24 Diabetes mellitus in pregnancy	0.448	0.552
O62.9 Abnormality of forces of labour, unspecified	0.448	0.552
O06 Unspecified abortion	0.449	0.551
O66.3 Obstructed labour due to other abnormalities of foetus	0.451	0.549
O66.1 Obstructed labour due to locked twins	0.451	0.549
O61.0 Failed medical induction of labour	0.451	0.549
O46.0 Antepartum haemorrhage with coagulation defect	0.452	0.548
O44.0 Placenta praevia specified as without haemorrhage	0.452	0.548
O91 Infections of breast associated with childbirth	0.453	0.547
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.454	0.545
O43.1 Malformation of placenta	0.456	0.544
O32 Maternal care for known or suspected malpresentation of foetus	0.456	0.544
O75.7 Vaginal delivery following previous Caesarean section	0.457	0.543
O61.8 Other failed induction of labour	0.458	0.541
O66.8 Other specified obstructed labour	0.458	0.541
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.459	0.541
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.459	0.541
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.459	0.541
O65.2 Obstructed labour due to pelvic inlet contraction	0.459	0.541
O65.1 Obstructed labour due to generally contracted pelvis	0.459	0.541
O65.0 Obstructed labour due to deformed pelvis	0.459	0.541
O75.4 Other complications of obstetric surgery and procedures	0.460	0.540
O75.1 Shock during or following labour and delivery	0.460	0.540
O66.9 Obstructed labour, unspecified	0.460	0.540
O08 Complications following abortion and ectopic and molar pregnancy	0.460	0.540
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.460	0.540
O34 Maternal care for known or suspected abnormality of pelvic organs	0.460	0.539
O75.2 Pyrexia during labour, not elsewhere classified	0.461	0.539
O43.2 Morbidly adherent placenta	0.462	0.538
O41.8 Other specified disorders of amniotic fluid and membranes	0.462	0.538
O89 Complications of anaesthesia during the puerperium	0.464	0.535
O71.6 Obstetric damage to pelvic joints and ligaments	0.465	0.535
O20.9 Haemorrhage in early pregnancy, unspecified	0.466	0.534
O75.9 Complication of labour and delivery, unspecified	0.466	0.533
O71.3 Obstetric laceration of cervix	0.467	0.533
O88 Obstetric embolism	0.467	0.533
O14.9 Preeclampsia, unspecified	0.469	0.531
O71.5 Other obstetric injury to pelvic organs	0.471	0.529
O61.9 Failed induction of labour, unspecified	0.473	0.527
O43.0 Placental transfusion syndromes	0.475	0.524
O64.4 Obstructed labour due to shoulder presentation	0.476	0.523
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.478	0.522
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.478	0.522
O71.2 Postpartum inversion of uterus	0.479	0.521
O71.1 Rupture of uterus during labour	0.479	0.521
O71.0 Rupture of uterus before onset of labour	0.479	0.521
O71.8 Other specified obstetric trauma	0.479	0.521
O47.0 False labour before 37 completed weeks of gestation	0.479	0.520
O47.9 False labour, unspecified	0.480	0.520
O03.4 Incomplete, without complication	0.481	0.519
O71.4 Obstetric high vaginal laceration alone	0.481	0.518
O64.5 Obstructed labour due to compound presentation	0.481	0.518
O71.7 Obstetric haematoma of pelvis	0.482	0.518
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.482	0.518
O64.3 Obstructed labour due to brow presentation	0.483	0.517
O90 Complications of the puerperium, not elsewhere classified	0.484	0.516
O00 Ectopic pregnancy	0.485	0.515
O64.2 Obstructed labour due to face presentation	0.486	0.514
O80.9 Single spontaneous delivery, unspecified	0.487	0.512
O14.2 HELLP syndrome	0.487	0.512
O03.3 Incomplete, with other and unspecified complications	0.488	0.511
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.488	0.511
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.488	0.511
O92 Other disorders of breast and lactation associated with childbirth	0.489	0.511
O60.3 Preterm delivery without spontaneous labour	0.489	0.511
O60.2 Preterm spontaneous labour with term delivery	0.489	0.511
O60.1 Preterm spontaneous labour with preterm delivery	0.489	0.511
O60.0 Preterm labour without delivery	0.489	0.511
O21.8 Other vomiting complicating pregnancy	0.491	0.509
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.491	0.509
O44.1 Placenta praevia with haemorrhage	0.492	0.508
O71.9 Obstetric trauma, unspecified	0.492	0.508
O81.5 Delivery by combination of forceps and vacuum extractor	0.492	0.508
O81.2 Mid-cavity forceps with rotation	0.492	0.508
O81.1 Mid-cavity forceps delivery	0.492	0.508
O67.9 Intrapartum haemorrhage, unspecified	0.495	0.505
O67.0 Intrapartum haemorrhage with coagulation defect	0.495	0.505
O21.2 Late vomiting of pregnancy	0.496	0.503
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.497	0.503
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.497	0.503
O64.8 Obstructed labour due to other malposition and malpresentation	0.497	0.503
O20.8 Other haemorrhage in early pregnancy	0.502	0.498
O86 Other puerperal infections	0.502	0.498
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.502	0.497
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.502	0.497
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.502	0.497
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.502	0.497
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.502	0.497
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.503	0.496
O74.8 Other complications of anaesthesia during labour and delivery	0.503	0.496
O74.7 Failed or difficult intubation during labour and delivery	0.503	0.496
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.503	0.496
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.503	0.496
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.503	0.496
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.503	0.496
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.503	0.496
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.504	0.496
O67.8 Other intrapartum haemorrhage	0.504	0.495
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.505	0.495
O64.1 Obstructed labour due to breech presentation	0.506	0.494
O75.0 Maternal distress during labour and delivery	0.506	0.494
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.507	0.492
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.508	0.492
O02.0 Blighted ovum and nonhydatidiform mole	0.509	0.491
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.509	0.491
O81.3 Other and unspecified forceps delivery	0.510	0.489
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.510	0.489
O33.5 Maternal care for disproportion due to unusually large foetus	0.511	0.489
O41.1 Infection of amniotic sac and membranes	0.514	0.485
O03.7 Complete or unspecified, complicated by embolism	0.515	0.485
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.515	0.485
O03.2 Incomplete, complicated by embolism	0.515	0.485
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.515	0.485
O45.8 Other premature separation of placenta	0.515	0.485
O45.0 Premature separation of placenta with coagulation defect	0.515	0.485
O02.1 Missed abortion	0.516	0.484
O14.1 Severe preeclampsia	0.516	0.483
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.517	0.483
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.517	0.482
O81.0 Low forceps delivery	0.518	0.482
O83.9 Assisted single delivery, unspecified	0.518	0.481
O83.8 Other specified assisted single delivery	0.518	0.481
O83.4 Destructive operation for delivery	0.518	0.481
O83.3 Delivery of viable foetus in abdominal pregnancy	0.518	0.481
O83.2 Other manipulation-assisted delivery	0.518	0.481
O83.0 Breech extraction	0.518	0.481
O84.9 Multiple delivery, unspecified	0.519	0.481
O84.8 Other multiple delivery	0.519	0.481
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.519	0.481
O84.0 Multiple delivery, all spontaneous	0.519	0.481
O33.8 Maternal care for disproportion of other origin	0.520	0.480
O33.7 Maternal care for disproportion due to other foetal deformities	0.520	0.480
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.520	0.480
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.520	0.480
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.520	0.480
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.520	0.480
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.520	0.480
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.520	0.480
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.521	0.479
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.521	0.479
O31.0 Papyraceous foetus	0.524	0.476
O83.1 Other assisted breech delivery	0.524	0.475
O84.2 Multiple delivery, all by Caesarean section	0.526	0.474
O03.8 Complete or unspecified, with other and unspecified complications	0.527	0.473
O45.9 Premature separation of placenta, unspecified	0.527	0.472
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.528	0.472
O31.1 Continuing pregnancy after abortion of one foetus or more	0.529	0.471
O15.9 Eclampsia, unspecified as to time period	0.530	0.469
O15.1 Eclampsia in labour	0.530	0.469
O15.0 Eclampsia in pregnancy	0.530	0.469
O30.9 Multiple gestation, unspecified	0.532	0.468
O30.8 Other multiple gestation	0.532	0.468
O30.2 Quadruplet pregnancy	0.532	0.468
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.533	0.467
O31.8 Other complications specific to multiple gestation	0.533	0.467
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.533	0.467
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.533	0.467
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.533	0.467
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.533	0.467
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.533	0.467
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.533	0.466
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.534	0.466
O23.5 Infections of the genital tract in pregnancy	0.534	0.466
O15.2 Eclampsia in the puerperium	0.535	0.465
O41.0 Oligohydramnios	0.537	0.463
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.538	0.462
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.538	0.462
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.539	0.461
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.539	0.461
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.539	0.460
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.540	0.460
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.540	0.460
O26.0 Excessive weight gain in pregnancy	0.541	0.459
O30.1 Triplet pregnancy	0.543	0.457
O26.4 Herpes gestationis	0.547	0.453
O26.1 Low weight gain in pregnancy	0.547	0.453
O26.2 Pregnancy care of habitual aborter	0.547	0.453
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.547	0.452
O04 Medical abortion	0.548	0.451
O33.9 Maternal care for disproportion, unspecified	0.549	0.451
O02.8 Other specified abnormal products of conception	0.550	0.450
O26.8 Other specified pregnancy-related conditions	0.551	0.449
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.552	0.448
O23.3 Infections of other parts of urinary tract in pregnancy	0.553	0.447
O23.2 Infections of urethra in pregnancy	0.553	0.447
O23.1 Infections of bladder in pregnancy	0.553	0.447
O12.0 Gestational oedema	0.553	0.447
O26.5 Maternal hypotension syndrome	0.553	0.446
O87.2 Haemorrhoids in the puerperium	0.554	0.446
O23.4 Unspecified infection of urinary tract in pregnancy	0.554	0.446
O12.1 Gestational proteinuria	0.554	0.445
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.555	0.444
O02.9 Abnormal product of conception, unspecified	0.555	0.444
O30.0 Twin pregnancy	0.557	0.443
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.557	0.442
O12.2 Gestational oedema with proteinuria	0.559	0.441
O23.0 Infections of kidney in pregnancy	0.560	0.440
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.560	0.439
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.563	0.436
O47.1 False labour at or after 37 completed weeks of gestation	0.564	0.436
O01.0 Classical hydatidiform mole	0.568	0.432
O01.9 Hydatidiform mole, unspecified	0.568	0.432
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.569	0.431
O29.8 Other complications of anaesthesia during pregnancy	0.569	0.431
O29.6 Failed or difficult intubation during pregnancy	0.569	0.431
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.569	0.431
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.569	0.431
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.569	0.431
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.569	0.431
O29.1 Cardiac complications of anaesthesia during pregnancy	0.569	0.431
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.569	0.431
O28.8 Other abnormal findings on antenatal screening of mother	0.569	0.431
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.569	0.431
O28.4 Abnormal radiological finding on antenatal screening of mother	0.569	0.431
O28.2 Abnormal cytological finding on antenatal screening of mother	0.569	0.431
O22.3 Deep phlebothrombosis in pregnancy	0.570	0.430
O28.0 Abnormal haematological finding on antenatal screening of mother	0.575	0.425
O22.9 Venous complication in pregnancy, unspecified	0.579	0.421
O22.8 Other venous complications in pregnancy	0.579	0.421
O22.5 Cerebral venous thrombosis in pregnancy	0.579	0.421
O22.2 Superficial thrombophlebitis in pregnancy	0.579	0.421
O01.1 Incomplete and partial hydatidiform mole	0.580	0.420
O34.4 Maternal care for other abnormalities of cervix	0.581	0.419
O22.4 Haemorrhoids in pregnancy	0.582	0.417
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.584	0.416
O22.1 Genital varices in pregnancy	0.585	0.414
O34.5 Maternal care for other abnormalities of gravid uterus	0.588	0.412
O22.0 Varicose veins of lower extremity in pregnancy	0.592	0.407
O32.0 Maternal care for unstable lie	0.593	0.407
O05.9 Complete or unspecified, without complication	0.596	0.403
O05.8 Complete or unspecified, with other and unspecified complications	0.596	0.403
O05.7 Complete or unspecified, complicated by embolism	0.596	0.403
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.596	0.403
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.596	0.403
O05.4 Incomplete, without complication	0.596	0.403
O05.3 Incomplete, with other and unspecified complications	0.596	0.403
O05.2 Incomplete, complicated by embolism	0.596	0.403
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.596	0.403
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.596	0.403
O91.2 Nonpurulent mastitis associated with childbirth	0.599	0.401
O07.9 Other and unspecified failed attempted abortion, without complication	0.599	0.400
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.599	0.400
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.599	0.400
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.599	0.400
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.599	0.400
O07.3 Failed medical abortion, with other and unspecified complications	0.599	0.400
O07.2 Failed medical abortion, complicated by embolism	0.599	0.400
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.599	0.400
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.599	0.400
O87.3 Cerebral venous thrombosis in the puerperium	0.599	0.400
O87.1 Deep phlebothrombosis in the puerperium	0.599	0.400
O32.9 Maternal care for malpresentation of foetus, unspecified	0.600	0.400
O96.9 Death from unspecified obstetric cause	0.601	0.399
O96.1 Death from indirect obstetric cause	0.601	0.399
O96.0 Death from direct obstetric cause	0.601	0.399
O97.9 Death from sequelae of obstetric cause, unspecified	0.601	0.399
O97.1 Death from sequelae of indirect obstetric cause	0.601	0.399
O97.0 Death from sequelae of direct obstetric cause	0.601	0.399
O91.1 Abscess of breast associated with childbirth	0.603	0.397
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.603	0.397
O07.4 Failed medical abortion, without complication	0.604	0.396
O24.3 Pre-existing diabetes mellitus, unspecified	0.604	0.396
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.604	0.396
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.604	0.396
O87.9 Venous complication in the puerperium, unspecified	0.604	0.396
O32.8 Maternal care for other malpresentation of foetus	0.604	0.395
O06.8 Complete or unspecified, with other and unspecified complications	0.605	0.395
O06.7 Complete or unspecified, complicated by embolism	0.605	0.395
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.605	0.395
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.605	0.395
O06.3 Incomplete, with other and unspecified complications	0.605	0.395
O06.2 Incomplete, complicated by embolism	0.605	0.395
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.605	0.395
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.605	0.395
O32.3 Maternal care for face, brow and chin presentation	0.606	0.394
O24.9 Diabetes mellitus in pregnancy, unspecified	0.606	0.394
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.607	0.393
O91.0 Infection of nipple associated with childbirth	0.608	0.392
O06.4 Incomplete, without complication	0.609	0.390
O87.8 Other venous complications in the puerperium	0.610	0.390
O87.0 Superficial thrombophlebitis in the puerperium	0.611	0.389
O06.9 Complete or unspecified, without complication	0.611	0.389
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.613	0.387
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.613	0.387
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.613	0.387
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.613	0.387
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.613	0.387
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.613	0.387
O08.3 Shock following abortion and ectopic and molar pregnancy	0.613	0.387
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.613	0.387
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.613	0.387
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.613	0.387
O20.0 Threatened abortion	0.613	0.387
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.613	0.387
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.616	0.384
O89.8 Other complications of anaesthesia during the puerperium	0.616	0.384
O89.6 Failed or difficult intubation during the puerperium	0.616	0.384
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.616	0.384
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.616	0.384
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.616	0.384
O89.1 Cardiac complications of anaesthesia during the puerperium	0.616	0.384
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.616	0.384
O90.1 Disruption of perineal obstetric wound	0.616	0.384
O32.6 Maternal care for compound presentation	0.616	0.383
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.617	0.383
O88.8 Other obstetric embolism	0.618	0.382
O88.3 Obstetric pyaemic and septic embolism	0.618	0.382
O88.2 Obstetric blood-clot embolism	0.618	0.382
O88.1 Amniotic fluid embolism	0.618	0.382
O88.0 Obstetric air embolism	0.618	0.382
O34.6 Maternal care for abnormality of vagina	0.618	0.381
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.619	0.381
O34.8 Maternal care for other abnormalities of pelvic organs	0.624	0.376
O34.0 Maternal care for congenital malformation of uterus	0.625	0.375
O90.0 Disruption of Caesarean section wound	0.625	0.375
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.626	0.374
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.627	0.373
O32.2 Maternal care for transverse and oblique lie	0.627	0.373
O86.1 Other infection of genital tract following delivery	0.628	0.372
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.628	0.371
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.629	0.370
O32.4 Maternal care for high head at term	0.629	0.370
O90.5 Postpartum thyroiditis	0.630	0.370
O90.4 Postpartum acute renal failure	0.630	0.370
O90.3 Cardiomyopathy in the puerperium	0.630	0.370
O86.2 Urinary tract infection following delivery	0.630	0.369
O00.8 Other ectopic pregnancy	0.630	0.369
O00.2 Ovarian pregnancy	0.630	0.369
O00.0 Abdominal pregnancy	0.630	0.369
O34.1 Maternal care for tumour of corpus uteri	0.632	0.368
O92.7 Other and unspecified disorders of lactation	0.633	0.367
O92.6 Galactorrhoea	0.633	0.367
O92.5 Suppressed lactation	0.633	0.367
O92.4 Hypogalactia	0.633	0.367
O92.3 Agalactia	0.633	0.367
O92.0 Retracted nipple associated with childbirth	0.633	0.367
O34.3 Maternal care for cervical incompetence	0.634	0.366
O92.1 Cracked nipple associated with childbirth	0.634	0.366
O90.9 Complication of the puerperium, unspecified	0.635	0.365
O26.9 Pregnancy-related condition, unspecified	0.636	0.364
O86.3 Other genito-urinary tract infections following delivery	0.643	0.357
O00.1 Tubal pregnancy	0.643	0.357
O90.2 Haematoma of obstetric wound	0.645	0.354
O24.4 Diabetes mellitus arising in pregnancy	0.647	0.353
O90.8 Other complications of the puerperium, not elsewhere classified	0.647	0.352
O86.8 Other specified puerperal infections	0.649	0.351
O92.2 Other and unspecified disorders of breast associated with childbirth	0.654	0.346
O34.7 Maternal care for abnormality of vulva and perineum	0.654	0.345
O86.0 Infection of obstetric surgical wound	0.661	0.338
O00.9 Ectopic pregnancy, unspecified	0.662	0.337
O04.4 Incomplete, without complication	0.665	0.335
O04.7 Complete or unspecified, complicated by embolism	0.676	0.324
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.676	0.324
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.676	0.324
O04.3 Incomplete, with other and unspecified complications	0.676	0.324

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations