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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs440454
log Bayes Factor = 233.155
Chromosome 6   position 31,927,342  (GRCh37) Explore rs440454 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
B37.8 Candidiasis of other sites
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
B37 Candidiasis
1.000 0.000 0.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
B35-B49 Mycoses
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
K90-K93 Other diseases of the digestive system
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
L40 Psoriasis
0.000 0.002 0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.003 0.997
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
E27 Other disorders of adrenal gland
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
M06 Other rheumatoid arthritis
0.001 0.005 0.995
D69.6 Thrombocytopenia, unspecified
0.994 0.006 0.000
L40.5 Arthropathic psoriasis
0.000 0.006 0.994
M05 Seropositive rheumatoid arthritis
0.002 0.007 0.991
M05-M14 Inflammatory polyarthropathies
0.006 0.008 0.986
K52.8 Other specified non-infective gastro-enteritis and colitis
0.988 0.012 0.000
D80-D89 Certain disorders involving the immune mechanism
0.987 0.013 0.000
D68 Other coagulation defects
0.987 0.013 0.000
K52 Other non-infective gastro-enteritis and colitis
0.987 0.013 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.983 0.017 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.017 0.983
E50-E64 Other nutritional deficiencies
0.983 0.017 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.980 0.020 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.978 0.022 0.000
E04 Other non-toxic goitre
0.977 0.023 0.000
E70-E90 Metabolic disorders
0.977 0.023 0.000
B25-B34 Other viral diseases
0.973 0.027 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.972 0.028 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
D50-D53 Nutritional anaemias
0.970 0.030 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.031 0.969
E89.0 Postprocedural hypothyroidism
0.968 0.032 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.967 0.033 0.000
L50-L54 Urticaria and erythema
0.965 0.035 0.000
A63.0 Anogenital (venereal) warts
0.964 0.036 0.000
B25 Cytomegaloviral disease
0.964 0.036 0.000
B07 Viral warts
0.962 0.038 0.000
G37 Other demyelinating diseases of central nervous system
0.961 0.039 0.000
E83 Disorders of mineral metabolism
0.959 0.041 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.041 0.959
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.959 0.041 0.000
E04.2 Non-toxic multinodular goitre
0.959 0.041 0.000
B25.9 Cytomegaloviral disease, unspecified
0.957 0.043 0.000
L10-L14 Bullous disorders
0.957 0.043 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.955 0.045 0.000
M35.0 Sicca syndrome [Sjogren]
0.952 0.048 0.000
E83.1 Disorders of iron metabolism
0.950 0.050 0.000
K90.9 Intestinal malabsorption, unspecified
0.950 0.050 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.050 0.950
M06.3 Rheumatoid nodule
0.000 0.052 0.948
L52 Erythema nodosum
0.947 0.053 0.000
D72 Other disorders of white blood cells
0.947 0.053 0.000
B37.9 Candidiasis, unspecified
0.942 0.058 0.000
D86 Sarcoidosis
0.937 0.063 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.936 0.064 0.000
E53 Deficiency of other B group vitamins
0.923 0.077 0.000
K35-K38 Diseases of appendix
0.922 0.078 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.919 0.081 0.000
L13 Other bullous disorders
0.913 0.087 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.912 0.088 0.000
D72.8 Other specified disorders of white blood cells
0.909 0.091 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.907 0.093 0.000
D76.3 Other histiocytosis syndromes
0.905 0.095 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.905 0.095 0.000
D86.9 Sarcoidosis, unspecified
0.897 0.103 0.000
E34 Other endocrine disorders
0.897 0.103 0.000
L20-L30 Dermatitis and eczema
0.895 0.105 0.000
K51.5 Mucosal proctocolitis
0.893 0.107 0.000
D68.8 Other specified coagulation defects
0.891 0.109 0.000
D51 Vitamin B12 deficiency anaemia
0.890 0.110 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.115 0.885
K51.2 Ulcerative (chronic) proctitis
0.884 0.116 0.000
L13.0 Dermatitis herpetiformis
0.883 0.117 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.881 0.119 0.000
M35 Other systemic involvement of connective tissue
0.881 0.119 0.000
K37 Unspecified appendicitis
0.872 0.128 0.000
Chapter II Neoplasms
0.871 0.129 0.000
E73 Lactose intolerance
0.869 0.131 0.000
M20-M25 Other joint disorders
0.869 0.131 0.000
D80 Immunodeficiency with predominantly antibody defects
0.869 0.131 0.000
E83.5 Disorders of calcium metabolism
0.863 0.137 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.863 0.137 0.000
L40.0 Psoriasis vulgaris
0.000 0.138 0.862
E53.8 Deficiency of other specified B group vitamins
0.860 0.140 0.000
C88 Malignant immunoproliferative diseases
0.856 0.144 0.000
E55 Vitamin D deficiency
0.856 0.144 0.000
M34 Systemic sclerosis
0.856 0.144 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.855 0.145 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.146 0.854
L40.8 Other psoriasis
0.000 0.147 0.853
D68.0 Von Willebrand's disease
0.853 0.147 0.000
D50 Iron deficiency anaemia
0.852 0.148 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.852 0.148 0.000
C34 Malignant neoplasm of bronchus and lung
0.852 0.148 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.150 0.850
G37.9 Demyelinating disease of central nervous system, unspecified
0.850 0.150 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.151 0.849
T39.1 4-Aminophenol derivatives
0.000 0.152 0.848
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.152 0.848
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.847 0.153 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.847 0.153 0.000
E04.0 Non-toxic diffuse goitre
0.847 0.153 0.000
D69.5 Secondary thrombocytopenia
0.847 0.153 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.847 0.153 0.000
D69.4 Other primary thrombocytopenia
0.843 0.157 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.838 0.162 0.000
E06 Thyroiditis
0.837 0.163 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.835 0.165 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.835 0.165 0.000
L12 Pemphigoid
0.833 0.167 0.000
C92 Myeloid leukaemia
0.833 0.167 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.168 0.832
D68.2 Hereditary deficiency of other clotting factors
0.827 0.173 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.822 0.178 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.822 0.178 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.822 0.178 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.821 0.179 0.000
M32 Systemic lupus erythematosus
0.818 0.182 0.000
E34.9 Endocrine disorder, unspecified
0.817 0.183 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.184 0.816
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.816 0.184 0.000
E31 Polyglandular dysfunction
0.815 0.185 0.000
K51.8 Other ulcerative colitis
0.813 0.186 0.000
D69.8 Other specified haemorrhagic conditions
0.812 0.188 0.000
B44 Aspergillosis
0.812 0.188 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.812 0.188 0.000
E61 Deficiency of other nutrient elements
0.810 0.190 0.000
K38 Other diseases of appendix
0.809 0.191 0.000
L21 Seborrhoeic dermatitis
0.809 0.191 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.192 0.808
G55.0 Nerve root and plexus compressions in neoplastic disease
0.807 0.193 0.000
C92.0 Acute myeloid leukaemia
0.805 0.195 0.000
D68.5 Primary Thrombophilia
0.803 0.197 0.000
G00 Bacterial meningitis, not elsewhere classified
0.801 0.199 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.801 0.199 0.000
D60-D64 Aplastic and other anaemias
0.799 0.201 0.000
D55-D59 Haemolytic anaemias
0.798 0.202 0.000
B37.1 Pulmonary candidiasis
0.796 0.204 0.000
E73.9 Lactose intolerance, unspecified
0.793 0.207 0.000
M34.8 Other forms of systemic sclerosis
0.792 0.208 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.208 0.792
C34.3 Lower lobe, bronchus or lung
0.790 0.210 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.212 0.788
C88.0 Waldenstrom's macroglobulinaemia
0.787 0.212 0.000
B01 Varicella [chickenpox]
0.787 0.213 0.000
D69.2 Other nonthrombocytopenic purpura
0.786 0.214 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.215 0.785
M34.9 Systemic sclerosis, unspecified
0.785 0.215 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.784 0.216 0.000
B36 Other superficial mycoses
0.784 0.216 0.000
E51 Thiamine deficiency
0.782 0.218 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.782 0.218 0.000
D72.1 Eosinophilia
0.781 0.219 0.000
E27.2 Addisonian crisis
0.781 0.219 0.000
M07 Psoriatic and enteropathic arthropathies
0.003 0.219 0.779
D89.0 Polyclonal hypergammaglobulinaemia
0.781 0.219 0.000
L27 Dermatitis due to substances taken internally
0.777 0.223 0.000
C91 Lymphoid leukaemia
0.773 0.227 0.000
E04.9 Non-toxic goitre, unspecified
0.771 0.229 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.769 0.231 0.000
D70 Agranulocytosis
0.768 0.232 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.233 0.767
L40-L45 Papulosquamous disorders
0.239 0.233 0.527
C85.1 B-cell lymphoma, unspecified
0.766 0.234 0.000
D52 Folate deficiency anaemia
0.766 0.234 0.000
E55.9 Vitamin D deficiency, unspecified
0.765 0.235 0.000
G30-G32 Other degenerative diseases of the nervous system
0.763 0.237 0.000
D68.9 Coagulation defect, unspecified
0.762 0.238 0.000
C34.9 Bronchus or lung, unspecified
0.759 0.241 0.000
E79 Disorders of purine and pyrimidine metabolism
0.758 0.242 0.000
B37.2 Candidiasis of skin and nail
0.758 0.242 0.000
L50 Urticaria
0.756 0.244 0.000
C90.0 Multiple myeloma
0.755 0.245 0.000
C34.1 Upper lobe, bronchus or lung
0.750 0.250 0.000
G58 Other mononeuropathies
0.749 0.251 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.251 0.748
L21.9 Seborrhoeic dermatitis, unspecified
0.748 0.252 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.252 0.748
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.747 0.253 0.000
E53.9 Vitamin B deficiency, unspecified
0.744 0.256 0.000
D86.1 Sarcoidosis of lymph nodes
0.744 0.256 0.000
L51 Erythema multiforme
0.743 0.256 0.000
E05.8 Other thyrotoxicosis
0.743 0.257 0.000
C90.2 Plasmacytoma, extramedullary
0.743 0.257 0.000
C94 Other leukaemias of specified cell type
0.740 0.260 0.000
D64 Other anaemias
0.739 0.261 0.000
D68.6 Other Thrombophilia
0.739 0.261 0.000
E20 Hypoparathyroidism
0.738 0.262 0.000
B37.4 Candidiasis of other urogenital sites
0.736 0.264 0.000
D53 Other nutritional anaemias
0.735 0.265 0.000
D89.1 Cryoglobulinaemia
0.735 0.265 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.733 0.267 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.267 0.733
E83.9 Disorder of mineral metabolism, unspecified
0.731 0.269 0.000
L40.1 Generalised pustular psoriasis
0.000 0.271 0.729
D59 Acquired haemolytic anaemia
0.728 0.272 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.273 0.727
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.726 0.274 0.000
L11 Other acantholytic disorders
0.726 0.274 0.000
D86.0 Sarcoidosis of lung
0.724 0.276 0.000
E58 Dietary calcium deficiency
0.723 0.277 0.000
A65-A69 Other spirochaetal diseases
0.722 0.277 0.000
M31 Other necrotising vasculopathies
0.722 0.278 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.722 0.278 0.000
A63.8 Other specified predominantly sexually transmitted diseases
0.722 0.278 0.000
G00.9 Bacterial meningitis, unspecified
0.720 0.280 0.000
L26 Exfoliative dermatitis
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
D67 Hereditary factor IX deficiency
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
B37.6 Candidal endocarditis
0.717 0.283 0.000
B37.5 Candidal meningitis
0.717 0.283 0.000
B48 Other mycoses, not elsewhere classified
0.717 0.283 0.000
B47 Mycetoma
0.717 0.283 0.000
B46 Zygomycosis
0.717 0.283 0.000
B45 Cryptococcosis
0.717 0.283 0.000
B43 Chromomycosis and phaeomycotic abscess
0.717 0.283 0.000
B42 Sporotrichosis
0.717 0.283 0.000
B41 Paracoccidioidomycosis
0.717 0.283 0.000
B40 Blastomycosis
0.717 0.283 0.000
B39 Histoplasmosis
0.717 0.283 0.000
B38 Coccidioidomycosis
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.717 0.283 0.000
D69.1 Qualitative platelet defects
0.716 0.283 0.000
C93 Monocytic leukaemia
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
L40.4 Guttate psoriasis
0.000 0.284 0.715
L40.2 Acrodermatitis continua
0.000 0.284 0.715
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.285 0.715
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.285 0.715
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.285 0.715
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.285 0.715
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.285 0.715
E27.5 Adrenomedullary hyperfunction
0.714 0.286 0.000
E27.0 Other adrenocortical overactivity
0.714 0.286 0.000
L53 Other erythematous conditions
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E25 Adrenogenital disorders
0.714 0.286 0.000
E06.3 Autoimmune thyroiditis
0.714 0.286 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.714
C34.2 Middle lobe, bronchus or lung
0.714 0.286 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.001 0.286 0.713
M08 Juvenile arthritis
0.004 0.287 0.709
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.288 0.710
M05.2 Rheumatoid vasculitis
0.002 0.288 0.710
M05.1 Rheumatoid lung disease
0.002 0.288 0.710
M05.0 Felty's syndrome
0.002 0.288 0.710
D50.1 Sideropenic dysphagia
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.004 0.289 0.707
E27.4 Other and unspecified adrenocortical insufficiency
0.711 0.289 0.000
M34.0 Progressive systemic sclerosis
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.291 0.709
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.708 0.292 0.000
B08.1 Molluscum contagiosum
0.708 0.292 0.000
E28 Ovarian dysfunction
0.708 0.292 0.000
D81 Combined immunodeficiencies
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
A59 Trichomoniasis
0.705 0.295 0.000
A56 Other sexually transmitted chlamydial diseases
0.705 0.295 0.000
A54 Gonococcal infection
0.705 0.295 0.000
A53 Other and unspecified syphilis
0.705 0.295 0.000
A52 Late syphilis
0.705 0.295 0.000
A51 Early syphilis
0.705 0.295 0.000
A50 Congenital syphilis
0.705 0.295 0.000
A64 Unspecified sexually transmitted disease
0.705 0.295 0.000
A58 Granuloma inguinale
0.705 0.295 0.000
A57 Chancroid
0.705 0.295 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.705 0.295 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.704 0.295 0.000
E63 Other nutritional deficiencies
0.704 0.295 0.000
E50 Vitamin A deficiency
0.704 0.295 0.000
E60 Dietary zinc deficiency
0.704 0.295 0.000
E59 Dietary selenium deficiency
0.704 0.295 0.000
E54 Ascorbic acid deficiency
0.704 0.295 0.000
E52 Niacin deficiency [pellagra]
0.704 0.295 0.000
D61 Other aplastic anaemias
0.704 0.296 0.000
K52.3 Indeterminate colitis
0.704 0.296 0.000
B37.7 Candidal septicaemia
0.703 0.296 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
C51-C58 Malignant neoplasms of female genital organs
0.703 0.297 0.000
E70 Disorders of aromatic amino-acid metabolism
0.703 0.297 0.000
D74 Methaemoglobinaemia
0.702 0.297 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.702 0.297 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.702 0.297 0.000
M05.8 Other seropositive rheumatoid arthritis
0.002 0.298 0.700
B27 Infectious mononucleosis
0.702 0.298 0.000
G58.8 Other specified mononeuropathies
0.701 0.298 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.701 0.299 0.000
B06 Rubella [German measles]
0.701 0.299 0.000
B05 Measles
0.701 0.299 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.701 0.299 0.000
B04 Monkeypox
0.701 0.299 0.000
B03 Smallpox
0.701 0.299 0.000
E04.8 Other specified non-toxic goitre
0.700 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.700 0.300 0.000
E76 Disorders of glycosaminoglycan metabolism
0.700 0.300 0.000
E72 Other disorders of amino-acid metabolism
0.700 0.300 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.700 0.300 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.700 0.300 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.700 0.300 0.000
L12.0 Bullous pemphigoid
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
B44.9 Aspergillosis, unspecified
0.698 0.302 0.000
B30 Viral conjunctivitis
0.698 0.302 0.000
B26 Mumps
0.698 0.302 0.000
K90.8 Other intestinal malabsorption
0.695 0.305 0.000
B25.0 Cytomegaloviral pneumonitis
0.695 0.305 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.694 0.306 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.694 0.306 0.000
E89.5 Postprocedural testicular hypofunction
0.694 0.306 0.000
E89.1 Postprocedural hypoinsulinaemia
0.694 0.306 0.000
L54 Erythema in diseases classified elsewhere
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.692 0.308 0.000
B25.2 Cytomegaloviral pancreatitis
0.691 0.309 0.000
B25.1 Cytomegaloviral hepatitis
0.691 0.309 0.000
D64.8 Other specified anaemias
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.310 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.310 0.690
G37.5 Concentric sclerosis [Balo]
0.689 0.311 0.000
G37.4 Subacute necrotising myelitis
0.689 0.311 0.000
G37.2 Central pontine myelinolysis
0.689 0.311 0.000
G37.1 Central demyelination of corpus callosum
0.689 0.311 0.000
G37.0 Diffuse sclerosis
0.689 0.311 0.000
I10 Essential (primary) hypertension
0.000 0.311 0.689
E89.4 Postprocedural ovarian failure
0.688 0.312 0.000
E83.8 Other disorders of mineral metabolism
0.688 0.312 0.000
E83.2 Disorders of zinc metabolism
0.688 0.312 0.000
E83.0 Disorders of copper metabolism
0.688 0.312 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.313 0.687
L10 Pemphigus
0.686 0.314 0.000
L14 Bullous disorders in diseases classified elsewhere
0.686 0.314 0.000
E61.2 Magnesium deficiency
0.685 0.315 0.000
G36 Other acute disseminated demyelination
0.685 0.315 0.000
E31.0 Autoimmune polyglandular failure
0.685 0.315 0.000
K38.8 Other specified diseases of appendix
0.683 0.317 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.317 0.683
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.317 0.683
B25.8 Other cytomegaloviral diseases
0.681 0.319 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.320 0.680
M06.38 Rheumatoid nodule (Other)
0.000 0.320 0.680
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.320 0.680
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.320 0.680
M06.33 Rheumatoid nodule (Forearm)
0.000 0.320 0.680
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.320 0.680
D72.9 Disorder of white blood cells, unspecified
0.679 0.321 0.000
D72.0 Genetic anomalies of leukocytes
0.679 0.321 0.000
L23 Allergic contact dermatitis
0.679 0.321 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
L12.1 Cicatricial pemphigoid
0.677 0.323 0.000
D84 Other immunodeficiencies
0.677 0.323 0.000
G00.1 Pneumococcal meningitis
0.676 0.324 0.000
E56 Other vitamin deficiencies
0.676 0.324 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.675 0.325 0.000
C81 Hodgkin's disease
0.675 0.325 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.674 0.326 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.674 0.326 0.000
D66 Hereditary factor VIII deficiency
0.674 0.326 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.674 0.326 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.672 0.328 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.328 0.672
D76.2 Haemophagocytic syndrome, infection-associated
0.671 0.329 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.671 0.329 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.671 0.329 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.671 0.329 0.000
G20-G26 Extrapyramidal and movement disorders
0.670 0.330 0.000
B50-B64 Protozoal diseases
0.670 0.330 0.000
C34.0 Main bronchus
0.668 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.668 0.332 0.000
E06.9 Thyroiditis, unspecified
0.668 0.332 0.000
M06.1 Adult-onset Still's disease
0.001 0.334 0.666
B33 Other viral diseases, not elsewhere classified
0.666 0.334 0.000
T39.0 Salicylates
0.000 0.334 0.666
G09 Sequelae of inflammatory diseases of central nervous system
0.666 0.334 0.000
C90.1 Plasma cell leukaemia
0.664 0.336 0.000
M00-M03 Infectious arthropathies
0.664 0.336 0.000
M35.1 Other overlap syndromes
0.664 0.336 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.664 0.336 0.000
M35.8 Other specified systemic involvement of connective tissue
0.663 0.337 0.000
D68.1 Hereditary factor XI deficiency
0.662 0.337 0.000
E53.1 Pyridoxine deficiency
0.662 0.338 0.000
E53.0 Riboflavin deficiency
0.662 0.338 0.000
D82 Immunodeficiency associated with other major defects
0.661 0.338 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.339 0.661
E34.0 Carcinoid syndrome
0.660 0.340 0.000
C90.3 Solitary plasmacytoma
0.659 0.341 0.000
D83 Common variable immunodeficiency
0.656 0.344 0.000
L13.9 Bullous disorder, unspecified
0.655 0.345 0.000
L13.8 Other specified bullous disorders
0.655 0.345 0.000
L13.1 Subcorneal pustular dermatitis
0.655 0.345 0.000
D86.3 Sarcoidosis of skin
0.655 0.345 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.654 0.346 0.000
E34.8 Other specified endocrine disorders
0.654 0.346 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.653 0.346 0.000
C91.1 Chronic lymphocytic leukaemia
0.653 0.347 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.653 0.347 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.653 0.347 0.000
L50.1 Idiopathic urticaria
0.652 0.348 0.000
C34.8 Overlapping lesion of bronchus and lung
0.651 0.349 0.000
C31 Malignant neoplasm of accessory sinuses
0.651 0.349 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.349 0.651
M34.1 CR(E)ST syndrome
0.650 0.350 0.000
D89.3 Immune reconstitution syndrome
0.650 0.350 0.000
L30 Other dermatitis
0.650 0.350 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.650 0.350 0.000
C85.0 Lymphosarcoma
0.649 0.351 0.000
K51.4 Pseudopolyposis of colon
0.648 0.352 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.644 0.356 0.000
M31.0 Hypersensitivity angiitis
0.644 0.356 0.000
E34.5 Androgen resistance syndrome
0.643 0.357 0.000
E34.4 Constitutional tall stature
0.643 0.357 0.000
E34.3 Short stature, not elsewhere classified
0.643 0.357 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.643 0.357 0.000
E34.1 Other hypersecretion of intestinal hormones
0.643 0.357 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.643 0.357 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.643 0.357 0.000
L24 Irritant contact dermatitis
0.641 0.359 0.000
L22 Diaper [napkin] dermatitis
0.641 0.359 0.000
B35 Dermatophytosis
0.640 0.360 0.000
K38.9 Disease of appendix, unspecified
0.639 0.361 0.000
E51.2 Wernicke's encephalopathy
0.639 0.361 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.638 0.362 0.000
D51.2 Transcobalamin II deficiency
0.638 0.362 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.638 0.362 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.637 0.363 0.000
G52 Disorders of other cranial nerves
0.637 0.363 0.000
D59.1 Other autoimmune haemolytic anaemias
0.637 0.363 0.000
G00.2 Streptococcal meningitis
0.634 0.366 0.000
N20.0 Calculus of kidney
0.000 0.367 0.633
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.632 0.368 0.000
D69.9 Haemorrhagic condition, unspecified
0.631 0.368 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.631 0.368 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.631 0.368 0.000
M35.5 Multifocal fibrosclerosis
0.631 0.368 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.631 0.368 0.000
M11 Other crystal arthropathies
0.004 0.369 0.627
L25 Unspecified contact dermatitis
0.630 0.370 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.629 0.371 0.000
C83.0 Small cell (diffuse)
0.629 0.371 0.000
B36.9 Superficial mycosis, unspecified
0.629 0.371 0.000
C91.0 Acute lymphoblastic leukaemia
0.628 0.372 0.000
M40-M43 Deforming dorsopathies
0.628 0.372 0.000
M07.3 Other psoriatic arthropathies
0.000 0.373 0.627
K91.4 Colostomy and enterostomy malfunction
0.625 0.375 0.000
B01.2 Varicella pneumonia
0.624 0.376 0.000
L20 Atopic dermatitis
0.624 0.376 0.000
D61.9 Aplastic anaemia, unspecified
0.624 0.376 0.000
E73.8 Other lactose intolerance
0.623 0.377 0.000
E73.1 Secondary lactase deficiency
0.623 0.377 0.000
E73.0 Congenital lactase deficiency
0.623 0.377 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.623 0.377 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.623 0.377 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.623 0.377 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.623 0.377 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.623 0.377 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.622 0.378 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.378 0.622
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.620 0.380 0.000
D52.9 Folate deficiency anaemia, unspecified
0.619 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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