TreeWAS – Variant ID: rs441810

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27 Other disorders of adrenal gland	0.000	0.483	0.517
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.484	0.516
E27.1 Primary adrenocortical insufficiency	0.000	0.490	0.510
E27.2 Addisonian crisis	0.000	0.529	0.471
E27.8 Other specified disorders of adrenal gland	0.000	0.547	0.453
E27.9 Disorder of adrenal gland, unspecified	0.000	0.590	0.410
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.618	0.382
E27.5 Adrenomedullary hyperfunction	0.000	0.629	0.371
E27.0 Other adrenocortical overactivity	0.000	0.629	0.371
E20-E35 Disorders of other endocrine glands	0.000	0.887	0.113
E26 Hyperaldosteronism	0.000	0.903	0.097
E29 Testicular dysfunction	0.000	0.910	0.090
E23 Hypofunction and other disorders of pituitary gland	0.000	0.912	0.088
E24 Cushing's syndrome	0.000	0.913	0.087
E26.0 Primary hyperaldosteronism	0.000	0.914	0.086
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.919	0.081
E32 Diseases of thymus	0.000	0.919	0.081
E31 Polyglandular dysfunction	0.000	0.919	0.081
E30 Disorders of puberty, not elsewhere classified	0.000	0.919	0.081
E20 Hypoparathyroidism	0.000	0.920	0.080
E23.0 Hypopituitarism	0.000	0.925	0.075
E29.1 Testicular hypofunction	0.000	0.926	0.073
E25 Adrenogenital disorders	0.000	0.927	0.072
E26.9 Hyperaldosteronism, unspecified	0.000	0.930	0.070
E26.8 Other hyperaldosteronism	0.000	0.930	0.070
E26.1 Secondary hyperaldosteronism	0.000	0.930	0.070
E24.9 Cushing's syndrome, unspecified	0.000	0.932	0.067
E24.0 Pituitary-dependent Cushing's disease	0.000	0.934	0.066
E28 Ovarian dysfunction	0.000	0.934	0.066
E29.9 Testicular dysfunction, unspecified	0.000	0.935	0.065
E29.8 Other testicular dysfunction	0.000	0.935	0.065
E29.0 Testicular hyperfunction	0.000	0.935	0.065
E23.7 Disorder of pituitary gland, unspecified	0.000	0.935	0.065
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.936	0.063
E23.1 Drug-induced hypopituitarism	0.000	0.936	0.063
E24.8 Other Cushing's syndrome	0.000	0.937	0.063
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.937	0.063
E24.3 Ectopic ACTH syndrome	0.000	0.937	0.063
E24.1 Nelson's syndrome	0.000	0.937	0.063
E23.2 Diabetes insipidus	0.000	0.938	0.062
E34 Other endocrine disorders	0.000	0.939	0.061
E24.2 Drug-induced Cushing's syndrome	0.000	0.940	0.060
E22 Hyperfunction of pituitary gland	0.000	0.940	0.060
E30.9 Disorder of puberty, unspecified	0.000	0.941	0.058
E30.8 Other disorders of puberty	0.000	0.941	0.058
E30.1 Precocious puberty	0.000	0.941	0.058
E30.0 Delayed puberty	0.000	0.941	0.058
E31.9 Polyglandular dysfunction, unspecified	0.000	0.941	0.058
E31.8 Other polyglandular dysfunction	0.000	0.941	0.058
E31.1 Polyglandular hyperfunction	0.000	0.941	0.058
E31.0 Autoimmune polyglandular failure	0.000	0.941	0.058
E32.9 Disease of thymus, unspecified	0.000	0.941	0.058
E32.8 Other diseases of thymus	0.000	0.941	0.058
E32.1 Abscess of thymus	0.000	0.941	0.058
E32.0 Persistent hyperplasia of thymus	0.000	0.941	0.058
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.941	0.058
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.941	0.058
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.941	0.058
E20.8 Other hypoparathyroidism	0.000	0.943	0.057
E20.1 Pseudohypoparathyroidism	0.000	0.943	0.057
E20.0 Idiopathic hypoparathyroidism	0.000	0.943	0.057
E20.9 Hypoparathyroidism, unspecified	0.000	0.944	0.056
E23.6 Other disorders of pituitary gland	0.000	0.945	0.055
E25.9 Adrenogenital disorder, unspecified	0.000	0.948	0.052
E25.8 Other adrenogenital disorders	0.000	0.948	0.052
E28.3 Primary ovarian failure	0.000	0.951	0.049
E28.9 Ovarian dysfunction, unspecified	0.000	0.952	0.047
E28.8 Other ovarian dysfunction	0.000	0.952	0.047
E28.1 Androgen excess	0.000	0.952	0.047
E28.0 Oestrogen excess	0.000	0.952	0.047
E22.0 Acromegaly and pituitary gigantism	0.000	0.953	0.047
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.954	0.046
E34.5 Androgen resistance syndrome	0.000	0.956	0.044
E34.4 Constitutional tall stature	0.000	0.956	0.044
E34.3 Short stature, not elsewhere classified	0.000	0.956	0.044
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.956	0.044
E34.1 Other hypersecretion of intestinal hormones	0.000	0.956	0.044
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.956	0.043
E34.0 Carcinoid syndrome	0.000	0.956	0.044
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.957	0.043
E22.8 Other hyperfunction of pituitary gland	0.000	0.957	0.043
E22.1 Hyperprolactinaemia	0.000	0.961	0.039
E34.9 Endocrine disorder, unspecified	0.000	0.962	0.038
E34.8 Other specified endocrine disorders	0.000	0.966	0.034
E21.4 Other specified disorders of parathyroid gland	0.000	0.966	0.033
E21.2 Other hyperparathyroidism	0.000	0.966	0.033
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.967	0.032
E21.0 Primary hyperparathyroidism	0.000	0.969	0.031
E28.2 Polycystic ovarian syndrome	0.000	0.971	0.029
E21.3 Hyperparathyroidism, unspecified	0.000	0.971	0.029
K04.5 Chronic apical periodontitis	0.000	0.975	0.025
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.979	0.021
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.980	0.019
L91.8 Other hypertrophic disorders of skin	0.000	0.989	0.011
L91.0 Keloid scar	0.000	0.991	0.009
L91 Hypertrophic disorders of skin	0.000	0.991	0.009
Y95 Nosocomial condition	0.000	0.991	0.009
L91.9 Hypertrophic disorder of skin, unspecified	0.000	0.993	0.007
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.994	0.006
N41.1 Chronic prostatitis	0.000	0.995	0.005
M67.8 Other specified disorders of synovium and tendon	0.005	0.995	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.995	0.005
L08.8 Other specified local infections of skin and subcutaneous tissue	0.005	0.995	0.000
Y57.9 Drug or medicament, unspecified	0.005	0.995	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.996	0.004
F52.2 Failure of genital response	0.000	0.996	0.004
Q63.0 Accessory kidney	0.000	0.996	0.004
R01.0 Benign and innocent cardiac murmurs	0.004	0.996	0.000
J06.9 Acute upper respiratory infection, unspecified	0.004	0.996	0.000
K04.3 Abnormal hard tissue formation in pulp	0.000	0.996	0.004
K04.2 Pulp degeneration	0.000	0.996	0.004
K04.1 Necrosis of pulp	0.000	0.996	0.004
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
K04.0 Pulpitis	0.000	0.996	0.004
Y57 Other and unspecified drugs and medicaments	0.004	0.996	0.000
M67 Other disorders of synovium and tendon	0.004	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.997	0.003
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.000	0.997	0.003
Y57.6 Other diagnostic agents	0.003	0.997	0.000
T39.0 Salicylates	0.000	0.997	0.003
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.000	0.997	0.003
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.003	0.997	0.000
M67.3 Transient synovitis	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
E80.4 Gilbert's syndrome	0.003	0.997	0.000
K04.8 Radicular cyst	0.000	0.997	0.003
M67.1 Other contracture of tendon (sheath)	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.003	0.997	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.003	0.997	0.000
J06.0 Acute laryngopharyngitis	0.002	0.997	0.000
Y98 Lifestyle-related condition	0.000	0.997	0.002
Y97 Environmental-pollution-related condition	0.000	0.997	0.002
Y96 Work-related condition	0.000	0.997	0.002
M67.0 Short Achilles tendon (acquired)	0.002	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.997	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.000	0.997	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
M67.4 Ganglion	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.000	0.998	0.002
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.000	0.998	0.002
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
C71.9 Brain, unspecified	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y90.9 Presence of alcohol in blood, level not specified	0.000	0.998	0.002
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.000	0.998	0.002
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.000	0.998	0.002
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.000	0.998	0.002
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.000	0.998	0.002
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.000	0.998	0.002
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.000	0.998	0.002
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.000	0.998	0.002
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
M86.8 Other osteomyelitis	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.002	0.998	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.002	0.998	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.002	0.998	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.002	0.998	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.002	0.998	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.002	0.998	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.002	0.998	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.002	0.998	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.998	0.002
Q63.8 Other specified congenital malformations of kidney	0.000	0.998	0.002
Q63.3 Hyperplastic and giant kidney	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.000	0.998	0.002
Y91.3 Very severe alcohol intoxication	0.000	0.998	0.002
Y91.2 Severe alcohol intoxication	0.000	0.998	0.002
Y91.1 Moderate alcohol intoxication	0.000	0.998	0.002
Y91.0 Mild alcohol intoxication	0.000	0.998	0.002
M41 Scoliosis	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
F52.0 Lack or loss of sexual desire	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.000	0.998	0.002
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.002	0.998	0.000
M86.3 Chronic multifocal osteomyelitis	0.002	0.998	0.000
M86.2 Subacute osteomyelitis	0.002	0.998	0.000
M86.1 Other acute osteomyelitis	0.002	0.998	0.000
M86.0 Acute haematogenous osteomyelitis	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.000	0.998	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.001	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.002
K11.5 Sialolithiasis	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.998	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.002	0.998	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.002	0.998	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.002	0.998	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.001	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.001	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.001	0.998	0.000
M41.3 Thoracogenic scoliosis	0.001	0.998	0.000
M41.2 Other idiopathic scoliosis	0.001	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.001	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.998	0.001
Z51.8 Other specified medical care	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.000	0.998	0.002
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.001	0.998	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.001	0.998	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.001	0.998	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.001	0.998	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.001	0.998	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.18 Other acute osteomyelitis (Other)	0.001	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.001	0.998	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.14 Other acute osteomyelitis (Hand)	0.001	0.998	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.001	0.998	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.001	0.998	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.28 Subacute osteomyelitis (Other)	0.001	0.998	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.001	0.998	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.24 Subacute osteomyelitis (Hand)	0.001	0.998	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.001	0.998	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.001	0.998	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.001	0.998	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.001	0.998	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.001	0.998	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.001	0.998	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.001	0.998	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.001	0.998	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.001	0.998	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.001	0.998	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.001	0.998	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.001	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.001
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.001
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C18.5 Splenic flexure	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.001	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.001	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.001	0.998	0.000
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.998	0.002
S82.5 Fracture of medial malleolus	0.001	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.001	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.001
S86 Injury of muscle and tendon at lower leg level	0.001	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
J34.3 Hypertrophy of nasal turbinates	0.001	0.999	0.000
K82.8 Other specified diseases of gallbladder	0.001	0.999	0.000
Y43.4 Immunosuppressive agents	0.001	0.999	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.999	0.001
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.999	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.999	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.999	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.999	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.999	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.999	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.999	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.999	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.999	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.999	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.999	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.999	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.999	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations