TreeWAS – Variant ID: rs442309

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.881	0.119
S90-S99 Injuries to the ankle and foot	0.000	0.885	0.115
S93.1 Dislocation of toe(s)	0.000	0.886	0.114
S93.0 Dislocation of ankle joint	0.000	0.888	0.112
S92 Fracture of foot, except ankle	0.000	0.893	0.107
S91 Open wound of ankle and foot	0.000	0.894	0.106
S99 Other and unspecified injuries of ankle and foot	0.000	0.897	0.103
S91.1 Open wound of toe(s) without damage to nail	0.000	0.898	0.102
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.900	0.100
S99.9 Unspecified injury of ankle and foot	0.000	0.905	0.095
S92.1 Fracture of talus	0.000	0.906	0.094
S97 Crushing injury of ankle and foot	0.000	0.908	0.092
S92.0 Fracture of calcaneus	0.000	0.909	0.091
S92.7 Multiple fractures of foot	0.000	0.912	0.088
S93.4 Sprain and strain of ankle	0.000	0.914	0.086
S93.5 Sprain and strain of toe(s)	0.000	0.914	0.086
S92.10 Fracture of talus (closed)	0.000	0.915	0.085
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.915	0.084
S90 Superficial injury of ankle and foot	0.000	0.916	0.084
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.916	0.084
S98 Traumatic amputation of ankle and foot	0.000	0.917	0.083
S95 Injury of blood vessels at ankle and foot level	0.000	0.917	0.083
S94 Injury of nerves at ankle and foot level	0.000	0.917	0.083
S92.00 Fracture of calcaneus (closed)	0.000	0.920	0.080
S91.3 Open wound of other parts of foot	0.000	0.921	0.079
S92.5 Fracture of other toe	0.000	0.922	0.078
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.922	0.078
S91.7 Multiple open wounds of ankle and foot	0.000	0.924	0.076
S92.2 Fracture of other tarsal bone(s)	0.000	0.924	0.075
S92.70 Multiple fractures of foot (closed)	0.000	0.926	0.074
S92.3 Fracture of metatarsal bone	0.000	0.926	0.074
S92.4 Fracture of great toe	0.000	0.926	0.074
S99.7 Multiple injuries of ankle and foot	0.000	0.926	0.074
S91.2 Open wound of toe(s) with damage to nail	0.000	0.928	0.072
S92.9 Fracture of foot, unspecified	0.000	0.928	0.072
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.928	0.071
M81.99 Osteoporosis, unspecified (Site unspecified)	0.069	0.931	0.000
S91.0 Open wound of ankle	0.000	0.932	0.068
S92.11 Fracture of talus (open)	0.000	0.932	0.068
S90.3 Contusion of other and unspecified parts of foot	0.000	0.933	0.067
S99.8 Other specified injuries of ankle and foot	0.000	0.933	0.067
S97.0 Crushing injury of ankle	0.000	0.934	0.066
S92.01 Fracture of calcaneus (open)	0.000	0.934	0.066
S92.71 Multiple fractures of foot (open)	0.000	0.937	0.063
S90.0 Contusion of ankle	0.000	0.938	0.062
S97.1 Crushing injury of toe(s)	0.000	0.938	0.062
S93.40 Sprain of unspecified ligament of ankle	0.000	0.938	0.062
S90.8 Other superficial injuries of ankle and foot	0.000	0.938	0.062
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.939	0.061
S90.2 Contusion of toe(s) with damage to nail	0.000	0.939	0.061
S92.50 Fracture of other toe (closed)	0.000	0.940	0.060
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.940	0.060
S94.8 Injury of other nerves at ankle and foot level	0.000	0.940	0.060
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.940	0.060
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.940	0.060
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.940	0.060
S94.1 Injury of medial plantar nerve	0.000	0.940	0.060
S94.0 Injury of lateral plantar nerve	0.000	0.940	0.060
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.940	0.060
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.940	0.060
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.940	0.060
S95.2 Injury of dorsal vein of foot	0.000	0.940	0.060
S95.1 Injury of plantar artery of foot	0.000	0.940	0.060
S95.0 Injury of dorsal artery of foot	0.000	0.940	0.060
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.940	0.060
S98.3 Traumatic amputation of other parts of foot	0.000	0.940	0.060
S98.2 Traumatic amputation of two or more toes	0.000	0.940	0.060
S98.1 Traumatic amputation of one toe	0.000	0.940	0.060
S98.0 Traumatic amputation of foot at ankle level	0.000	0.940	0.060
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.941	0.059
S92.40 Fracture of great toe (closed)	0.000	0.944	0.056
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.945	0.055
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.946	0.054
S92.31 Fracture of metatarsal bone (open)	0.000	0.946	0.053
S90.1 Contusion of toe(s) without damage to nail	0.000	0.947	0.053
S92.51 Fracture of other toe (open)	0.000	0.947	0.053
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.947	0.053
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.947	0.053
S92.91 Fracture of foot, unspecified (open)	0.000	0.948	0.052
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.948	0.051
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.948	0.051
S92.30 Fracture of metatarsal bone (closed)	0.000	0.949	0.051
S92.90 Fracture of foot, unspecified (closed)	0.000	0.953	0.046
S92.41 Fracture of great toe (open)	0.000	0.953	0.046
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.956	0.044
M81.9 Osteoporosis, unspecified	0.044	0.956	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.958	0.042
M81.90 Osteoporosis, unspecified (Multiple sites)	0.040	0.960	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.035	0.965	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.033	0.967	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.032	0.968	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.031	0.969	0.000
M81.98 Osteoporosis, unspecified (Other)	0.031	0.969	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.030	0.969	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.971	0.029
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.972	0.028
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.025	0.975	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.020	0.980	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.980	0.020
Z01.6 Radiological examination, not elsewhere classified	0.018	0.982	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.017	0.983	0.000
L60.0 Ingrowing nail	0.000	0.985	0.015
M81 Osteoporosis without pathological fracture	0.014	0.986	0.000
Q54.0 Hypospadias, balanic	0.013	0.987	0.000
Q54 Hypospadias	0.012	0.988	0.000
Q54.9 Hypospadias, unspecified	0.012	0.988	0.000
Z01.4 Gynaecological examination (general)(routine)	0.012	0.988	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.012	0.988	0.000
Z01.2 Dental examination	0.011	0.989	0.000
N43.3 Hydrocele, unspecified	0.000	0.989	0.011
M81.1 Postoophorectomy osteoporosis	0.010	0.990	0.000
M81.8 Other osteoporosis	0.010	0.990	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.010	0.990	0.000
M81.6 Localised osteoporosis [Lequesne]	0.010	0.990	0.000
M81.5 Idiopathic osteoporosis	0.010	0.990	0.000
M81.0 Postmenopausal osteoporosis	0.010	0.990	0.000
S43.0 Dislocation of shoulder joint	0.010	0.990	0.000
Q54.8 Other hypospadias	0.009	0.991	0.000
M77.4 Metatarsalgia	0.000	0.991	0.009
Q54.1 Hypospadias, penile	0.009	0.991	0.000
Z01.3 Examination of blood pressure	0.009	0.991	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.009	0.991	0.000
Q54.4 Congenital chordee	0.009	0.991	0.000
Q54.3 Hypospadias, perineal	0.009	0.991	0.000
Q54.2 Hypospadias, penoscrotal	0.009	0.991	0.000
Z01.1 Examination of ears and hearing	0.009	0.991	0.000
Z01.0 Examination of eyes and vision	0.009	0.991	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.008	0.992	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.008	0.992	0.000
M81.4 Drug-induced osteoporosis	0.008	0.992	0.000
M81.2 Osteoporosis of disuse	0.008	0.992	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.008	0.992	0.000
M81.80 Other osteoporosis (Multiple sites)	0.008	0.992	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.008	0.992	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.008	0.992	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.008	0.992	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.007	0.992	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.007	0.992	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.007	0.992	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.007	0.992	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.007	0.992	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.007	0.992	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.007	0.992	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.007	0.992	0.000
S43.1 Dislocation of acromioclavicular joint	0.008	0.992	0.000
M81.89 Other osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.88 Other osteoporosis (Other)	0.007	0.992	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.007	0.992	0.000
M81.86 Other osteoporosis (Lower leg)	0.007	0.992	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.007	0.992	0.000
M81.84 Other osteoporosis (Hand)	0.007	0.992	0.000
M81.83 Other osteoporosis (Forearm)	0.007	0.992	0.000
M81.82 Other osteoporosis (Upper arm)	0.007	0.992	0.000
M81.81 Other osteoporosis (Shoulder region)	0.007	0.992	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.007	0.992	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.007	0.992	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.007	0.992	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.007	0.992	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.007	0.992	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.007	0.992	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.007	0.992	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.007	0.992	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.007	0.993	0.000
M81.58 Idiopathic osteoporosis (Other)	0.007	0.993	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.007	0.993	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.007	0.993	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.007	0.993	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.007	0.993	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.007	0.993	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.007	0.993	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.007	0.993	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.007	0.993	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.007	0.993	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.007	0.993	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.007	0.993	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.007	0.993	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.007	0.993	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.007	0.993	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.007	0.993	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.007	0.993	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.007	0.993	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.007	0.993	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.007	0.993	0.000
S43.4 Sprain and strain of shoulder joint	0.007	0.993	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.007	0.993	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.007	0.993	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.007	0.993	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.007	0.993	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.007	0.993	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.007	0.993	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.007	0.993	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.007	0.993	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.007	0.993	0.000
M77.49 Metatarsalgia-Site unspec	0.000	0.993	0.007
M77.48 Metatarsalgia-Other	0.000	0.993	0.007
M77.46 Metatarsalgia-Lower Leg	0.000	0.993	0.007
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.993	0.007
M77.44 Metatarsalgia-Hand	0.000	0.993	0.007
M77.43 Metatarsalgia-Forearm	0.000	0.993	0.007
M77.42 Metatarsalgia-Upper arm	0.000	0.993	0.007
M77.41 Metatarsalgia-Shldr region	0.000	0.993	0.007
M77.40 Metatarsalgia-Mult sites	0.000	0.993	0.007
Z01.8 Other specified special examinations	0.007	0.993	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.007	0.993	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.007	0.993	0.000
S43.2 Dislocation of sternoclavicular joint	0.007	0.993	0.000
K27 Peptic ulcer, site unspecified	0.006	0.994	0.000
Z01.7 Laboratory examination	0.006	0.994	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.006	0.994	0.000
M81.48 Drug-induced osteoporosis (Other)	0.006	0.994	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.006	0.994	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.006	0.994	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.006	0.994	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.006	0.994	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.006	0.994	0.000
Z01.9 Special examination, unspecified	0.006	0.994	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.006	0.994	0.000
M81.28 Osteoporosis of disuse (Other)	0.006	0.994	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.006	0.994	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.006	0.994	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.006	0.994	0.000
M81.24 Osteoporosis of disuse (Hand)	0.006	0.994	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.006	0.994	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.006	0.994	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.005	0.994	0.000
Q55 Other congenital malformations of male genital organs	0.005	0.995	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.005	0.995	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.000	0.995	0.005
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.005	0.995	0.000
K27.5 Chronic or unspecified with perforation	0.005	0.995	0.000
K27.2 Acute with both haemorrhage and perforation	0.005	0.995	0.000
K27.1 Acute with perforation	0.005	0.995	0.000
K27.0 Acute with haemorrhage	0.005	0.995	0.000
K27.7 Chronic without haemorrhage or perforation	0.005	0.995	0.000
K27.4 Chronic or unspecified with haemorrhage	0.005	0.995	0.000
R23.3 Spontaneous ecchymoses	0.000	0.995	0.005
Q52 Other congenital malformations of female genitalia	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.995	0.005
D09.0 Bladder	0.005	0.995	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q55.6 Other congenital malformations of penis	0.004	0.996	0.000
K27.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
L60 Nail disorders	0.000	0.996	0.004
Q52.5 Fusion of labia	0.004	0.996	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.004	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.004	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.004	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.996	0.000
Q55.3 Atresia of vas deferens	0.004	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.004	0.996	0.000
Q55.0 Absence and aplasia of testis	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.996	0.001
L73.9 Follicular disorder, unspecified	0.000	0.996	0.004
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.004	0.996	0.000
R23 Other skin changes	0.000	0.996	0.004
L60.3 Nail dystrophy	0.000	0.996	0.004
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.996	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.996	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.996	0.000
Q52.3 Imperforate hymen	0.003	0.996	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.996	0.000
Q52.0 Congenital absence of vagina	0.003	0.996	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.000	0.997	0.003
L60.4 Beau's lines	0.000	0.997	0.003
R23.2 Flushing	0.000	0.997	0.003
C44.0 Skin of lip	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.000	0.997	0.003
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
I65.2 Occlusion and stenosis of carotid artery	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.997	0.003
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
J33.9 Nasal polyp, unspecified	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
L60.1 Onycholysis	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.997	0.003
N43 Hydrocele and spermatocele	0.000	0.997	0.003
R23.0 Cyanosis	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.003	0.997	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
Q10.0 Congenital ptosis	0.003	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.003	0.997	0.000
L60.2 Onychogryphosis	0.000	0.997	0.003
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.997	0.002
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
Z75.5 Holiday relief care	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
R23.1 Pallor	0.000	0.997	0.003
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.997	0.000
M75.0 Adhesive capsulitis of shoulder	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.997	0.002
D84 Other immunodeficiencies	0.003	0.997	0.000
K29.2 Alcoholic gastritis	0.000	0.997	0.003
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.997	0.000
T25.3 Burn of third degree of ankle and foot	0.002	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.997	0.000
W07.0 Home	0.000	0.998	0.002
Q15 Other congenital malformations of eye	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
N43.4 Spermatocele	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.000	0.998	0.002
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q15.0 Congenital glaucoma	0.002	0.998	0.000
Q30.3 Congenital perforated nasal septum	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
L73 Other follicular disorders	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.000	0.998	0.002
W25.9 Unspecified place	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.002	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.002	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.002	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.002	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
Q11.1 Other anophthalmos	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
N43.2 Other hydrocele	0.000	0.998	0.002
N43.1 Infected hydrocele	0.000	0.998	0.002
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
K13.0 Diseases of lips	0.002	0.998	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
T20 Burn and corrosion of head and neck	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
J03 Acute tonsillitis	0.000	0.998	0.002
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.002	0.998	0.000
Q30.8 Other congenital malformations of nose	0.002	0.998	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.998	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.998	0.000
Q30.0 Choanal atresia	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
L73.8 Other specified follicular disorders	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.998	0.000
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
W07.9 Unspecified place	0.000	0.998	0.002
D48.5 Skin	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations