TreeWAS – Variant ID: rs4446368

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F20.0 Paranoid schizophrenia	0.000	0.968	0.032
F20 Schizophrenia	0.000	0.969	0.031
F22.0 Delusional disorder	0.000	0.971	0.029
F22 Persistent delusional disorders	0.000	0.971	0.029
F20.9 Schizophrenia, unspecified	0.000	0.973	0.027
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.973	0.027
F22.9 Persistent delusional disorder, unspecified	0.000	0.976	0.024
F20.5 Residual schizophrenia	0.000	0.976	0.024
F20.6 Simple schizophrenia	0.000	0.978	0.022
F20.4 Postschizophrenic depression	0.000	0.978	0.022
F20.3 Undifferentiated schizophrenia	0.000	0.978	0.022
F20.1 Hebephrenic schizophrenia	0.000	0.978	0.022
F20.8 Other schizophrenia	0.000	0.978	0.022
F20.2 Catatonic schizophrenia	0.000	0.978	0.021
F29 Unspecified nonorganic psychosis	0.000	0.979	0.021
F25 Schizoaffective disorders	0.000	0.979	0.021
F22.8 Other persistent delusional disorders	0.000	0.979	0.021
F21 Schizotypal disorder	0.000	0.980	0.020
F28 Other nonorganic psychotic disorders	0.000	0.980	0.020
F24 Induced delusional disorder	0.000	0.980	0.020
F25.1 Schizoaffective disorder, depressive type	0.000	0.982	0.018
F25.2 Schizoaffective disorder, mixed type	0.000	0.984	0.016
F25.8 Other schizoaffective disorders	0.000	0.985	0.015
F23 Acute and transient psychotic disorders	0.000	0.985	0.015
F25.0 Schizoaffective disorder, manic type	0.000	0.986	0.013
F25.9 Schizoaffective disorder, unspecified	0.000	0.987	0.012
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.988	0.011
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.989	0.011
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.989	0.011
F23.8 Other acute and transient psychotic disorders	0.000	0.989	0.010
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.989	0.010
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.011	0.989	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.991	0.009
L90.0 Lichen sclerosus et atrophicus	0.000	0.994	0.006
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.994	0.006
D07.5 Prostate	0.006	0.994	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.995	0.005
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.005	0.995	0.000
K85.9 Acute pancreatitis, unspecified	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.995	0.005
L90.5 Scar conditions and fibrosis of skin	0.000	0.995	0.005
H33.3 Retinal breaks without detachment	0.005	0.995	0.000
L90 Atrophic disorders of skin	0.000	0.996	0.004
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.004	0.996	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.004	0.996	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
Z71.9 Counselling, unspecified	0.004	0.996	0.000
C48.2 Peritoneum, unspecified	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.000	0.996	0.004
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
R22.2 Localised swelling, mass and lump, trunk	0.004	0.996	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
H53.0 Amblyopia ex anopsia	0.000	0.996	0.004
L89.1 Stage II decubitus ulcer	0.004	0.996	0.000
H35.4 Peripheral retinal degeneration	0.000	0.996	0.004
N13.6 Pyonephrosis	0.000	0.996	0.004
J93.9 Pneumothorax, unspecified	0.004	0.996	0.000
L90.6 Striae atrophicae	0.000	0.997	0.003
L90.4 Acrodermatitis chronica atrophicans	0.000	0.997	0.003
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.997	0.003
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.997	0.003
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.997	0.003
C71.9 Brain, unspecified	0.000	0.997	0.003
K85 Acute pancreatitis	0.003	0.997	0.000
L90.9 Atrophic disorder of skin, unspecified	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
C07 Malignant neoplasm of parotid gland	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.997	0.003
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
F02.0 Dementia in Pick's disease	0.000	0.997	0.003
L90.8 Other atrophic disorders of skin	0.000	0.997	0.003
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.997	0.003
H04.1 Other disorders of lachrymal gland	0.000	0.997	0.003
F00 Dementia in Alzheimer's disease	0.000	0.997	0.003
M13.94 Arthritis, unspecified (Hand)	0.000	0.997	0.003
F03 Unspecified dementia	0.000	0.997	0.003
H53.8 Other visual disturbances	0.000	0.997	0.003
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.997	0.003
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.003	0.997	0.000
K22.9 Disease of oesophagus, unspecified	0.000	0.997	0.003
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.997	0.003
C74 Malignant neoplasm of adrenal gland	0.000	0.997	0.003
K85.8 Other acute pancreatitis	0.003	0.997	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
R27.0 Ataxia, unspecified	0.000	0.997	0.003
G80 Infantile cerebral palsy	0.003	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.997	0.003
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
Z60.2 Living alone	0.000	0.997	0.003
K85.0 Idiopathic acute pancreatitis	0.002	0.997	0.000
C74.9 Adrenal gland, unspecified	0.000	0.997	0.002
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.997	0.003
G80.0 Spastic cerebral palsy	0.002	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.002
F09 Unspecified organic or symptomatic mental disorder	0.000	0.997	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.997	0.003
G91.9 Hydrocephalus, unspecified	0.000	0.997	0.003
K85.3 Drug-induced acute pancreatitis	0.002	0.997	0.000
M07.3 Other psoriatic arthropathies	0.002	0.997	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
C74.0 Cortex of adrenal gland	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
H53 Visual disturbances	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Z60.8 Other problems related to social environment	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
Z60 Problems related to social environment	0.000	0.998	0.002
C74.1 Medulla of adrenal gland	0.000	0.998	0.002
H92.0 Otalgia	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Z59.0 Homelessness	0.000	0.998	0.002
C75.5 Aortic body and other paraganglia	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
C75.1 Pituitary gland	0.000	0.998	0.002
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.002
F02.2 Dementia in Huntington's disease	0.000	0.998	0.002
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.002
N42.9 Disorder of prostate, unspecified	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
I12 Hypertensive renal disease	0.000	0.998	0.002
H53.4 Visual field defects	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.000	0.998	0.002
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
H53.5 Colour vision deficiencies	0.000	0.998	0.002
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
D07.1 Vulva	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C75.9 Endocrine gland, unspecified	0.000	0.998	0.002
C75.8 Pluriglandular involvement, unspecified	0.000	0.998	0.002
C75.4 Carotid body	0.000	0.998	0.002
C75.3 Pineal gland	0.000	0.998	0.002
C75.2 Craniopharyngeal duct	0.000	0.998	0.002
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
D07.4 Penis	0.002	0.998	0.000
D07.0 Endometrium	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.998	0.002
C75.0 Parathyroid gland	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
H53.6 Night blindness	0.000	0.998	0.002
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
S70.0 Contusion of hip	0.000	0.998	0.002
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.998	0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
W20.8 Other specified place	0.002	0.998	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.998	0.002
Z60.4 Social exclusion and rejection	0.000	0.998	0.002
Z60.3 Acculturation difficulty	0.000	0.998	0.002
Z60.1 Atypical parenting situation	0.000	0.998	0.002
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.998	0.002
D07.2 Vagina	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
Z60.9 Problem related to social environment, unspecified	0.000	0.998	0.002
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.002
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
Z59.1 Inadequate housing	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
H53.3 Other disorders of binocular vision	0.000	0.998	0.002
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
J93.8 Other pneumothorax	0.002	0.998	0.000
Y04.8 Other specified place	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
Z59.7 Insufficient social insurance and welfare support	0.000	0.998	0.002
Z59.6 Low income	0.000	0.998	0.002
Z59.5 Extreme poverty	0.000	0.998	0.002
Z59.3 Problems related to living in residential institution	0.000	0.998	0.002
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
Z59.4 Lack of adequate food	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
D13.1 Stomach	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.002
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.002
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
W25.9 Unspecified place	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
C13.9 Hypopharynx, unspecified	0.000	0.998	0.002
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.002
F07.0 Organic personality disorder	0.000	0.998	0.001
G62 Other polyneuropathies	0.000	0.998	0.002
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.001
F07.1 Postencephalitic syndrome	0.000	0.998	0.001
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.998	0.002
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.998	0.001
F06.5 Organic dissociative disorder	0.000	0.998	0.001
F06.4 Organic anxiety disorder	0.000	0.998	0.001
F06.1 Organic catatonic disorder	0.000	0.998	0.001
F06.0 Organic hallucinosis	0.000	0.998	0.001
K31.4 Gastric diverticulum	0.000	0.998	0.002
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
Y04.5 Trade and service area	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.001
Z64 Problems related to certain psychosocial circumstances	0.000	0.998	0.002
H34.0 Transient retinal artery occlusion	0.000	0.998	0.001
Z90.6 Acquired absence of other parts of urinary tract	0.000	0.998	0.002
C81.2 Mixed cellularity	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
Z37.2 Twins, both liveborn	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.998	0.000
C71.5 Cerebral ventricle	0.000	0.998	0.001
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.001
F06.3 Organic mood [affective] disorders	0.000	0.998	0.001
F01 Vascular dementia	0.000	0.998	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.998	0.000
W20.0 Home	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.001
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.001
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.001
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.001
Z61.1 Removal from home in childhood	0.000	0.998	0.001
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.001
C81 Hodgkin's disease	0.002	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.998	0.001
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.002
Z02.8 Other examinations for administrative purposes	0.002	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
C81.0 Lymphocytic predominance	0.001	0.998	0.000
F05.1 Delirium superimposed on dementia	0.000	0.998	0.001
C13 Malignant neoplasm of hypopharynx	0.000	0.998	0.001
C02.9 Tongue, unspecified	0.000	0.998	0.001
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.001
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.998	0.001
F80.1 Expressive language disorder	0.000	0.998	0.001
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
W20 Struck by thrown, projected or falling object	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.001
H34.1 Central retinal artery occlusion	0.000	0.998	0.001
E04 Other non-toxic goitre	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
Z58 Problems related to physical environment	0.000	0.998	0.001
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.998	0.001
H53.2 Diplopia	0.000	0.998	0.001
G62.0 Drug-induced polyneuropathy	0.000	0.999	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.999	0.001
Y04 Assault by bodily force	0.001	0.999	0.000
Z65 Problems related to other psychosocial circumstances	0.000	0.999	0.001
C02.4 Lingual tonsil	0.000	0.999	0.001
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.000	0.999	0.001
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
N75.1 Abscess of Bartholin's gland	0.001	0.999	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.001	0.999	0.000
R41.2 Retrograde amnesia	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
Y04.2 School, other institution and public administrative area	0.001	0.999	0.000
Z58.7 Exposure to tobacco smoke	0.000	0.999	0.001
Z62 Other problems related to upbringing	0.000	0.999	0.001
Z55 Problems related to education and literacy	0.000	0.999	0.001
D25.0 Submucous leiomyoma of uterus	0.000	0.999	0.001
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
Z61.8 Other negative life events in childhood	0.000	0.999	0.001
Z64.4 Discord with counsellors	0.000	0.999	0.001
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.999	0.001
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.999	0.001
Z64.1 Problems related to multiparity	0.000	0.999	0.001
R27 Other lack of coordination	0.000	0.999	0.001
Chapter V Mental and behavioural disorders	0.000	0.999	0.001
M07.69 Other enteropathic arthropathies (Site unspecified)	0.001	0.999	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.001	0.999	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.999	0.001
F05.8 Other delirium	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.999	0.000
Z58.5 Exposure to other pollution	0.000	0.999	0.001
M07 Psoriatic and enteropathic arthropathies	0.001	0.999	0.000
C02.1 Border of tongue	0.000	0.999	0.001
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.001	0.999	0.000
F01.8 Other vascular dementia	0.000	0.999	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.999	0.001
F01.2 Subcortical vascular dementia	0.000	0.999	0.001
F01.0 Vascular dementia of acute onset	0.000	0.999	0.001
M07.6 Other enteropathic arthropathies	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.001	0.999	0.000
C14.0 Pharynx, unspecified	0.000	0.999	0.001
C81.7 Other Hodgkin's disease	0.001	0.999	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.001	0.999	0.000
C81.3 Lymphocytic depletion	0.001	0.999	0.000
C81.1 Nodular sclerosis	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.000	0.999	0.001
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.999	0.001
M40.29 Other and unspecified kyphosis (Site unspecified)	0.001	0.999	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.999	0.001
C13.8 Overlapping lesion of hypopharynx	0.000	0.999	0.001
C13.2 Posterior wall of hypopharynx	0.000	0.999	0.001
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.999	0.001
C48.0 Retroperitoneum	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
Z56.0 Unemployment, unspecified	0.000	0.999	0.001
N42 Other disorders of prostate	0.001	0.999	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
M40.2 Other and unspecified kyphosis	0.001	0.999	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.999	0.001
T75.4 Effects of electric current	0.000	0.999	0.001
W20.9 Unspecified place	0.001	0.999	0.000
W20.6 Industrial and construction area	0.001	0.999	0.000
W20.5 Trade and service area	0.001	0.999	0.000
W20.4 Street and highway	0.001	0.999	0.000
W20.2 School, other institution and public administrative area	0.001	0.999	0.000
W20.7 Farm	0.001	0.999	0.000
W20.3 Sports and athletics area	0.001	0.999	0.000
W20.1 Residential institution	0.001	0.999	0.000
Z58.8 Other problems related to physical environment	0.000	0.999	0.001
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.999	0.001
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.999	0.001
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.999	0.001
C10 Malignant neoplasm of oropharynx	0.000	0.999	0.001
C00.0 External upper lip	0.000	0.999	0.001
C10.9 Oropharynx, unspecified	0.000	0.999	0.001
C13.0 Postcricoid region	0.000	0.999	0.001
E04.8 Other specified non-toxic goitre	0.000	0.999	0.001
I69.3 Sequelae of cerebral infarction	0.000	0.999	0.001
R41.1 Anterograde amnesia	0.000	0.999	0.001
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
Z58.9 Problem related to physical environment, unspecified	0.000	0.999	0.001
Z58.6 Inadequate drinking-water supply	0.000	0.999	0.001
Z58.4 Exposure to radiation	0.000	0.999	0.001
Z58.3 Exposure to soil pollution	0.000	0.999	0.001
Z58.2 Exposure to water pollution	0.000	0.999	0.001
Z58.0 Exposure to noise	0.000	0.999	0.001
F80 Specific developmental disorders of speech and language	0.000	0.999	0.001
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.000	0.999	0.001
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.999	0.001
C02.0 Dorsal surface of tongue	0.000	0.999	0.001
Y04.4 Street and highway	0.001	0.999	0.000
Y04.0 Home	0.001	0.999	0.000
Y04.7 Farm	0.001	0.999	0.000
Y04.6 Industrial and construction area	0.001	0.999	0.000
Y04.1 Residential institution	0.001	0.999	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.999	0.001
Z65.4 Victim of crime and terrorism	0.000	0.999	0.001
Z65.2 Problems related to release from prison	0.000	0.999	0.001
Z65.1 Imprisonment and other incarceration	0.000	0.999	0.001
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.999	0.001
M25.84 Other specified joint disorders (Hand)	0.000	0.999	0.001
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
F01.1 Multi-infarct dementia	0.000	0.999	0.001
R20.0 Anaesthesia of skin	0.000	0.999	0.001
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.999	0.001
Z55.8 Other problems relating to education and literacy	0.000	0.999	0.001
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.999	0.001
Z55.3 Underachievement in school	0.000	0.999	0.001
Z55.2 Failed examinations	0.000	0.999	0.001
Z55.1 Schooling unavailable and unattainable	0.000	0.999	0.001
Z55.0 Illiteracy and low-level literacy	0.000	0.999	0.001
Z62.9 Problem related to upbringing, unspecified	0.000	0.999	0.001
Z62.8 Other specified problems related to upbringing	0.000	0.999	0.001
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.999	0.001
Z62.5 Other problems related to neglect in upbringing	0.000	0.999	0.001
Z62.4 Emotional neglect of child	0.000	0.999	0.001
Z62.3 Hostility towards and scapegoating of child	0.000	0.999	0.001
Z62.2 Institutional upbringing	0.000	0.999	0.001
Z62.1 Parental overprotection	0.000	0.999	0.001
Z62.0 Inadequate parental supervision and control	0.000	0.999	0.001
C11 Malignant neoplasm of nasopharynx	0.000	0.999	0.001
C00 Malignant neoplasm of lip	0.000	0.999	0.001
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.001	0.999	0.000
M07.5 Arthropathy in ulcerative colitis	0.001	0.999	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.001	0.999	0.000
M07.2 Psoriatic spondylitis	0.001	0.999	0.000
M07.1 Arthritis mutilans	0.001	0.999	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.001	0.999	0.000
M22.8 Other disorders of patella	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.999	0.001
Y04.3 Sports and athletics area	0.001	0.999	0.000
Z56 Problems related to employment and unemployment	0.000	0.999	0.001
M07.68 Other enteropathic arthropathies (Other)	0.001	0.999	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.999	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.999	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.999	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.999	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.999	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.999	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.999	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.999	0.001
S82.60 Fracture of lateral malleolus (closed)	0.001	0.999	0.000
E88.2 Lipomatosis, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations