TreeWAS – Variant ID: rs444881

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J38.1 Polyp of vocal cord and larynx	0.000	0.428	0.572
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.937	0.063
J38.5 Laryngeal spasm	0.000	0.947	0.053
J38.2 Nodules of vocal cords	0.000	0.952	0.048
J38.0 Paralysis of vocal cords and larynx	0.000	0.960	0.040
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.037	0.963	0.000
J38.6 Stenosis of larynx	0.000	0.964	0.036
J38.7 Other diseases of larynx	0.000	0.965	0.035
J38.4 Oedema of larynx	0.000	0.967	0.033
M18 Arthrosis of first carpometacarpal joint	0.026	0.974	0.000
J38.3 Other diseases of vocal cords	0.000	0.975	0.025
M18.1 Other primary arthrosis of first carpometacarpal joint	0.024	0.976	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.023	0.977	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.020	0.980	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.019	0.981	0.000
J95.8 Other postprocedural respiratory disorders	0.019	0.981	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.019	0.981	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.018	0.981	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.018	0.981	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.018	0.981	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.017	0.983	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.016	0.984	0.000
J95.0 Tracheostomy malfunction	0.016	0.984	0.000
J95-J99 Other diseases of the respiratory system	0.016	0.984	0.000
J99.0 Rheumatoid lung disease	0.015	0.985	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.015	0.985	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.015	0.985	0.000
B44.1 Other pulmonary aspergillosis	0.015	0.985	0.000
J95.5 Postprocedural subglottic stenosis	0.014	0.986	0.000
J95.4 Mendelson's syndrome	0.014	0.986	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.014	0.986	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.014	0.986	0.000
J96 Respiratory failure, not elsewhere classified	0.012	0.988	0.000
M79.63 Pain in limb (Forearm)	0.010	0.990	0.000
D23.3 Skin of other and unspecified parts of face	0.010	0.990	0.000
J96.9 Respiratory failure, unspecified	0.008	0.991	0.000
J96.1 Chronic respiratory failure	0.008	0.991	0.000
J96.0 Acute respiratory failure	0.008	0.991	0.000
D33.3 Cranial nerves	0.008	0.992	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.992	0.008
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.993	0.007
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.993	0.007
D17.9 Benign lipomatous neoplasm, unspecified	0.007	0.993	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.007	0.993	0.000
N39.8 Other specified disorders of urinary system	0.000	0.993	0.007
B44 Aspergillosis	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.993	0.007
T43.2 Other and unspecified antidepressants	0.000	0.993	0.007
F33 Recurrent depressive disorder	0.000	0.993	0.007
J96.09 Acute respiratory failure; Type unspecified	0.006	0.994	0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.006	0.994	0.000
J96.00 Acute respiratory failure; Type I [hypoxic]	0.006	0.994	0.000
J96.19 Chronic respiratory failure; Type unspecified	0.006	0.994	0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.006	0.994	0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.006	0.994	0.000
J96.99 Respiratory failure, unspecified; Type unspecified	0.006	0.994	0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.006	0.994	0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.006	0.994	0.000
H43.3 Other vitreous opacities	0.006	0.994	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.994	0.006
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.994	0.006
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.994	0.006
Z04.3 Examination and observation following other accident	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
N42.8 Other specified disorders of prostate	0.000	0.994	0.006
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
T43.9 Psychotropic drug, unspecified	0.000	0.995	0.005
B44.9 Aspergillosis, unspecified	0.005	0.995	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.995	0.005
F33.8 Other recurrent depressive disorders	0.000	0.995	0.005
S51.9 Open wound of forearm, part unspecified	0.000	0.995	0.005
B44.7 Disseminated aspergillosis	0.005	0.995	0.000
B44.2 Tonsillar aspergillosis	0.005	0.995	0.000
B44.0 Invasive pulmonary aspergillosis	0.005	0.995	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
L40.5 Arthropathic psoriasis	0.005	0.995	0.000
B44.8 Other forms of aspergillosis	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
I69 Sequelae of cerebrovascular disease	0.000	0.995	0.005
N39.4 Other specified urinary incontinence	0.000	0.995	0.005
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.995	0.005
D33 Benign neoplasm of brain and other parts of central nervous system	0.005	0.995	0.000
N39.1 Persistent proteinuria, unspecified	0.000	0.996	0.004
L40 Psoriasis	0.004	0.996	0.000
N39 Other disorders of urinary system	0.000	0.996	0.004
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.996	0.004
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.996	0.004
S51.8 Open wound of other parts of forearm	0.000	0.996	0.004
S51 Open wound of forearm	0.000	0.996	0.004
L40.8 Other psoriasis	0.004	0.996	0.000
D33.0 Brain, supratentorial	0.004	0.996	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.996	0.004
F43.2 Adjustment disorders	0.000	0.996	0.004
L40.9 Psoriasis, unspecified	0.004	0.996	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.996	0.004
L40.1 Generalised pustular psoriasis	0.004	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.996	0.004
L40.4 Guttate psoriasis	0.004	0.996	0.000
N05.9 Unspecified	0.000	0.996	0.004
D33.4 Spinal cord	0.004	0.996	0.000
S51.0 Open wound of elbow	0.000	0.996	0.004
D33.9 Central nervous system, unspecified	0.003	0.996	0.000
D33.7 Other specified parts of central nervous system	0.003	0.996	0.000
D33.1 Brain, infratentorial	0.003	0.996	0.000
D33.2 Brain, unspecified	0.003	0.997	0.000
L40.2 Acrodermatitis continua	0.003	0.997	0.000
N39.2 Orthostatic proteinuria, unspecified	0.000	0.997	0.003
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.997	0.000
Z37.2 Twins, both liveborn	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.003
S51.7 Multiple open wounds of forearm	0.000	0.997	0.003
H93.1 Tinnitus	0.000	0.997	0.003
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
I44.7 Left bundle-branch block, unspecified	0.000	0.997	0.003
L40.0 Psoriasis vulgaris	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
Z04.1 Examination and observation following transport accident	0.000	0.997	0.003
F22.0 Delusional disorder	0.000	0.997	0.003
S80.8 Other superficial injuries of lower leg	0.000	0.997	0.003
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.997	0.003
N05 Unspecified nephritic syndrome	0.000	0.997	0.003
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.997	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
T51.0 Ethanol	0.000	0.998	0.002
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.002
Z04 Examination and observation for other reasons	0.000	0.998	0.002
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
T40.2 Other opioids	0.000	0.998	0.002
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
N05.8 Other	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
Z04.6 General psychiatric examination, requested by authority	0.000	0.998	0.002
D23.5 Skin of trunk	0.000	0.998	0.002
G12.2 Motor neuron disease	0.000	0.998	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.000	0.998	0.002
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
N05.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.000	0.998	0.002
L40-L45 Papulosquamous disorders	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.998	0.002
Z04.0 Blood-alcohol and blood-drug test	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
C18.4 Transverse colon	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.000	0.998	0.002
O43.1 Malformation of placenta	0.000	0.998	0.002
Z04.2 Examination and observation following work accident	0.000	0.998	0.002
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.002
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
R49.0 Dysphonia	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
Y40.3 Macrolides	0.002	0.998	0.000
L43 Lichen planus	0.002	0.998	0.000
L41 Parapsoriasis	0.002	0.998	0.000
T40.5 Cocaine	0.000	0.998	0.002
L44 Other papulosquamous disorders	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.000	0.998	0.002
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.000	0.998	0.002
F43.0 Acute stress reaction	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
L45 Papulosquamous disorders in diseases classified elsewhere	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.001
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.001
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.001
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.001
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.001
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.000	0.998	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.000	0.998	0.001
L41.1 Pityriasis lichenoides chronica	0.001	0.998	0.000
H10 Conjunctivitis	0.002	0.998	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
L44.0 Pityriasis rubra pilaris	0.001	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.001
T49.8 Other topical agents	0.000	0.998	0.001
T49.7 Dental drugs, topically applied	0.000	0.998	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.001
T49.2 Local astringents and local detergents	0.000	0.998	0.001
T49.1 Antipruritics	0.000	0.998	0.001
L43.0 Hypertrophic lichen planus	0.001	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.998	0.000
F10.4 Withdrawal state with delirium	0.000	0.998	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.998	0.000
M05.0 Felty's syndrome	0.001	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.001
M05.18 Rheumatoid lung disease (Other)	0.001	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.001	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.998	0.000
C04.9 Floor of mouth, unspecified	0.001	0.998	0.000
L41.9 Parapsoriasis, unspecified	0.001	0.998	0.000
L41.8 Other parapsoriasis	0.001	0.998	0.000
L41.5 Retiform parapsoriasis	0.001	0.998	0.000
L41.4 Large plaque parapsoriasis	0.001	0.998	0.000
L41.3 Small plaque parapsoriasis	0.001	0.998	0.000
L41.2 Lymphomatoid papulosis	0.001	0.998	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.001	0.998	0.000
L43.3 Subacute (active) lichen planus	0.001	0.998	0.000
L43.2 Lichenoid drug reaction	0.001	0.998	0.000
L43.1 Bullous lichen planus	0.001	0.998	0.000
H10.4 Chronic conjunctivitis	0.001	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.001
L44.9 Papulosquamous disorder, unspecified	0.001	0.998	0.000
L44.8 Other specified papulosquamous disorders	0.001	0.998	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.001	0.998	0.000
L44.3 Lichen ruber moniliformis	0.001	0.998	0.000
L44.2 Lichen striatus	0.001	0.998	0.000
L44.1 Lichen nitidus	0.001	0.998	0.000
S19.9 Unspecified injury of neck	0.000	0.998	0.001
S80.0 Contusion of knee	0.000	0.998	0.001
T36.4 Tetracyclines	0.000	0.998	0.001
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.4 Iron and its compounds	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
W49.9 Unspecified place	0.001	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.001	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.001
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.001
T41.4 Anaesthetic, unspecified	0.000	0.998	0.001
T41.3 Local anaesthetics	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
T41.1 Intravenous anaesthetics	0.000	0.998	0.001
T41.0 Inhaled anaesthetics	0.000	0.998	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.998	0.001
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.999	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.999	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
Q52.5 Fusion of labia	0.000	0.999	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
T59.9 Gases, fumes and vapours, unspecified	0.000	0.999	0.001
Y40.6 Rifamycins	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.999	0.001
H93.8 Other specified disorders of ear	0.000	0.999	0.001
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
Q52.4 Other congenital malformations of vagina	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
K38.1 Appendicular concretions	0.000	0.999	0.001
M05.2 Rheumatoid vasculitis	0.001	0.999	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
T37.5 Antiviral drugs	0.000	0.999	0.001
T37.4 Anthelminthics	0.000	0.999	0.001
T37.3 Other antiprotozoal drugs	0.000	0.999	0.001
T37.1 Antimycobacterial drugs	0.000	0.999	0.001
T37.0 Sulphonamides	0.000	0.999	0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
D13.3 Other and unspecified parts of small intestine	0.001	0.999	0.000
H10.3 Acute conjunctivitis, unspecified	0.001	0.999	0.000
H10.2 Other acute conjunctivitis	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.999	0.001
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
Y40.5 Aminoglycosides	0.001	0.999	0.000
F22 Persistent delusional disorders	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.999	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
Y40.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
Y40.2 Chloramphenicol group	0.001	0.999	0.000
M05.08 Felty's syndrome (Other)	0.001	0.999	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.999	0.000
M05.06 Felty's syndrome (Lower leg)	0.001	0.999	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.999	0.000
M05.04 Felty's syndrome (Hand)	0.001	0.999	0.000
M05.03 Felty's syndrome (Forearm)	0.001	0.999	0.000
M05.02 Felty's syndrome (Upper arm)	0.001	0.999	0.000
M05.01 Felty's syndrome (Shoulder region)	0.001	0.999	0.000
M05.00 Felty's syndrome (Multiple sites)	0.001	0.999	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.999	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.999	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.999	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.999	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.999	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.999	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.999	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.999	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.999	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.999	0.000
H93.3 Disorders of acoustic nerve	0.000	0.999	0.001
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T39.4 Antirheumatics, not elsewhere classified	0.000	0.999	0.001
T39.2 Pyrazolone derivatives	0.000	0.999	0.001
T39.0 Salicylates	0.000	0.999	0.001
T45.5 Anticoagulants	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
M05.09 Felty's syndrome (Site unspecified)	0.001	0.999	0.000
H10.8 Other conjunctivitis	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.000	0.999	0.001
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.999	0.001
T58 Toxic effect of carbon monoxide	0.000	0.999	0.001
N04.9 Unspecified	0.000	0.999	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
T59.8 Other specified gases, fumes and vapours	0.000	0.999	0.001
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.999	0.001
S52.10 Fracture of upper end of radius (closed)	0.001	0.999	0.000
L43.8 Other lichen planus	0.001	0.999	0.000
T36.3 Macrolides	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.5 Other oestrogens and progestogens	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
Z04.5 Examination and observation following other inflicted injury	0.001	0.999	0.001
F40 Phobic anxiety disorders	0.000	0.999	0.001
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
L42 Pityriasis rosea	0.001	0.999	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.999	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.999	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.999	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.999	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.999	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.999	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.999	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.999	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.999	0.000
H10.0 Mucopurulent conjunctivitis	0.001	0.999	0.000
J15.2 Pneumonia due to staphylococcus	0.001	0.999	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
T59.7 Carbon dioxide	0.000	0.999	0.001
T59.6 Hydrogen sulphide	0.000	0.999	0.001
T59.5 Fluorine gas and hydrogen fluoride	0.000	0.999	0.001
T59.4 Chlorine gas	0.000	0.999	0.001
T59.3 Lachrymogenic gas	0.000	0.999	0.001
T59.2 Formaldehyde	0.000	0.999	0.001
T59.1 Sulphur dioxide	0.000	0.999	0.001
T59.0 Nitrogen oxides	0.000	0.999	0.001
A87 Viral meningitis	0.001	0.999	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.999	0.001
F22.8 Other persistent delusional disorders	0.000	0.999	0.001
G72.9 Myopathy, unspecified	0.000	0.999	0.001
T39.1 4-Aminophenol derivatives	0.000	0.999	0.001
T42.3 Barbiturates	0.000	0.999	0.001
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
T47.7 Emetics	0.000	0.999	0.001
T47.5 Digestants	0.000	0.999	0.001
T47.4 Other laxatives	0.000	0.999	0.001
T47.3 Saline and osmotic laxatives	0.000	0.999	0.001
Y40.1 Cefalosporins and other -lactam antibiotics	0.001	0.999	0.000
C01 Malignant neoplasm of base of tongue	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.999	0.001
F40.0 Agoraphobia	0.000	0.999	0.001
F40.9 Phobic anxiety disorder, unspecified	0.000	0.999	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.999	0.001
W27.6 Industrial and construction area	0.001	0.999	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.001	0.999	0.000
T65 Toxic effect of other and unspecified substances	0.000	0.999	0.001
A87.2 Lymphocytic choriomeningitis	0.001	0.999	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.001	0.999	0.000
S06.9 Intracranial injury, unspecified	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
Z71.9 Counselling, unspecified	0.000	0.999	0.001
F81 Specific developmental disorders of scholastic skills	0.000	0.999	0.001
G80 Infantile cerebral palsy	0.000	0.999	0.001
K06 Other disorders of gingiva and edentulous alveolar ridge	0.001	0.999	0.000
T56 Toxic effect of metals	0.000	0.999	0.001
A87.0 Enteroviral meningitis	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.000	0.999	0.001
G80.1 Spastic diplegia	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.999	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
T62 Toxic effect of other noxious substances eaten as food	0.000	0.999	0.001
T60 Toxic effect of pesticides	0.000	0.999	0.001
T57 Toxic effect of other inorganic substances	0.000	0.999	0.001
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.999	0.001
T52 Toxic effect of organic solvents	0.000	0.999	0.001
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.999	0.001
T55 Toxic effect of soaps and detergents	0.000	0.999	0.001
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations