TreeWAS – Variant ID: rs4454866

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20 Acquired deformities of fingers and toes	0.000	0.936	0.064
M20.2 Hallux rigidus	0.000	0.939	0.061
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.942	0.058
M20.0 Deformity of finger(s)	0.000	0.942	0.058
M20.3 Other deformity of hallux (acquired)	0.000	0.944	0.056
M20.1 Hallux valgus (acquired)	0.000	0.944	0.056
M35.0 Sicca syndrome [Sjogren]	0.000	0.945	0.055
M20-M25 Other joint disorders	0.000	0.948	0.052
M35 Other systemic involvement of connective tissue	0.000	0.948	0.052
M33 Dermatopolymyositis	0.000	0.952	0.048
M24 Other specific joint derangements	0.000	0.953	0.047
M33.1 Other dermatomyositis	0.000	0.957	0.043
M20.4 Other hammer toe(s) (acquired)	0.000	0.957	0.043
M35.2 Behcet's disease	0.000	0.958	0.042
M32 Systemic lupus erythematosus	0.000	0.959	0.041
M22 Disorders of patella	0.000	0.960	0.040
M21 Other acquired deformities of limbs	0.000	0.960	0.040
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.961	0.039
M33.2 Polymyositis	0.000	0.961	0.039
M30 Polyarteritis nodosa and related conditions	0.000	0.961	0.039
M24.0 Loose body in joint	0.000	0.961	0.039
M33.9 Dermatopolymyositis, unspecified	0.000	0.962	0.038
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.962	0.038
M35.7 Hypermobility syndrome	0.000	0.962	0.037
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.962	0.037
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.962	0.037
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.962	0.037
M35.5 Multifocal fibrosclerosis	0.000	0.962	0.037
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.963	0.037
M35.8 Other specified systemic involvement of connective tissue	0.000	0.963	0.037
M24.5 Contracture of joint	0.000	0.964	0.036
M34 Systemic sclerosis	0.000	0.964	0.036
M33.0 Juvenile dermatomyositis	0.000	0.965	0.035
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.965	0.035
M24.7 Protrusio acetabuli	0.000	0.965	0.035
M21.6 Other acquired deformities of ankle and foot	0.000	0.966	0.034
M24.6 Ankylosis of joint	0.000	0.966	0.033
M24.9 Joint derangement, unspecified	0.000	0.966	0.033
M24.1 Other articular cartilage disorders	0.000	0.967	0.033
M22.0 Recurrent dislocation of patella	0.000	0.967	0.033
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.000	0.968	0.032
M24.2 Disorder of ligament	0.000	0.968	0.032
M22.3 Other derangements of patella	0.000	0.968	0.031
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.969	0.031
M24.07 Loose body in joint (Ankle and foot)	0.000	0.969	0.031
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.969	0.031
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.969	0.031
M21.8 Other specified acquired deformities of limbs	0.000	0.969	0.031
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.969	0.030
M24.01 Loose body in joint (Shoulder region)	0.000	0.970	0.030
M32.8 Other forms of systemic lupus erythematosus	0.000	0.970	0.030
M22.8 Other disorders of patella	0.000	0.970	0.030
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.970	0.030
M35.1 Other overlap syndromes	0.000	0.970	0.030
M24.04 Loose body in joint (Hand)	0.000	0.970	0.030
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.970	0.029
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.970	0.029
M21.9 Acquired deformity of limb, unspecified	0.000	0.971	0.029
M24.02 Loose body in joint (Upper arm)	0.000	0.971	0.029
M30.0 Polyarteritis nodosa	0.000	0.971	0.029
M22.1 Recurrent subluxation of patella	0.000	0.971	0.029
M21.1 Varus deformity, not elsewhere classified	0.000	0.971	0.029
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.971	0.028
M21.4 Flat foot [pes planus] (acquired)	0.000	0.971	0.028
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.972	0.028
M30.2 Juvenile polyarteritis	0.000	0.972	0.028
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.972	0.028
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.972	0.028
M24.51 Contracture of joint (Shoulder region)	0.000	0.972	0.028
M24.09 Loose body in joint (Site unspecified)	0.000	0.972	0.028
M24.08 Loose body in joint (Other)	0.000	0.972	0.028
M24.00 Loose body in joint (Multiple sites)	0.000	0.972	0.028
M24.52 Contracture of joint (Upper arm)	0.000	0.972	0.028
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.972	0.028
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.972	0.028
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.972	0.028
M24.06 Loose body in joint-Lower leg	0.000	0.972	0.028
M24.57 Contracture of joint (Ankle and foot)	0.000	0.972	0.028
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.972	0.027
M36.3 Arthropathy in other blood disorders	0.000	0.972	0.027
M36.2 Haemophilic arthropathy	0.000	0.972	0.027
M36.1 Arthropathy in neoplastic disease	0.000	0.972	0.027
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.972	0.027
M21.3 Wrist or foot drop (acquired)	0.000	0.972	0.027
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.973	0.027
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.973	0.027
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.973	0.027
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.973	0.027
M22.9 Disorder of patella, unspecified	0.000	0.973	0.027
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.973	0.027
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.973	0.027
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.973	0.027
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.973	0.027
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.973	0.027
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.973	0.027
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.973	0.027
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.973	0.027
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.973	0.027
M24.03 Loose body in joint (Forearm)	0.000	0.973	0.027
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.973	0.027
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.973	0.027
M24.54 Contracture of joint (Hand)	0.000	0.973	0.027
M20.5 Other deformities of toe(s) (acquired)	0.000	0.973	0.027
M24.59 Contracture of joint (Site unspecified)	0.000	0.974	0.026
M24.58 Contracture of joint (Other)	0.000	0.974	0.026
M24.53 Contracture of joint (Forearm)	0.000	0.974	0.026
M24.50 Contracture of joint (Multiple sites)	0.000	0.974	0.026
M21.7 Unequal limb length (acquired)	0.000	0.974	0.026
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.974	0.026
M34.1 CR(E)ST syndrome	0.000	0.974	0.026
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.974	0.026
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.974	0.026
M34.8 Other forms of systemic sclerosis	0.000	0.974	0.026
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.974	0.026
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.974	0.026
M22.2 Patellofemoral disorders	0.000	0.974	0.026
M21.2 Flexion deformity	0.000	0.974	0.025
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.975	0.025
M24.28 Disorder of ligament (Other)	0.000	0.975	0.025
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.975	0.025
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.975	0.025
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.975	0.025
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.975	0.025
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.975	0.025
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.975	0.025
M24.56 Contracture of joint (Lower leg)	0.000	0.975	0.025
M24.79 Protrusio acetabuli-Site unspec	0.000	0.975	0.025
M24.78 Protrusio acetabuli-Other	0.000	0.975	0.025
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.975	0.025
M24.76 Protrusio acetabuli-Lower leg	0.000	0.975	0.025
M24.74 Protrusio acetabuli-Hand	0.000	0.975	0.025
M24.73 Protrusio acetabuli-Forearm	0.000	0.975	0.025
M24.72 Protrusio acetabuli-Upper arm	0.000	0.975	0.025
M24.71 Protrusio acetabuli-Shldr region	0.000	0.975	0.025
M24.70 Protrusio acetabuli-Mult sites	0.000	0.975	0.025
M22.4 Chondromalacia patellae	0.000	0.975	0.025
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.975	0.025
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.975	0.025
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.975	0.025
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.975	0.025
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.975	0.025
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.975	0.025
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.975	0.025
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.975	0.025
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.975	0.025
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.975	0.025
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.975	0.025
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.975	0.025
M24.66 Ankylosis of joint (Lower leg)	0.000	0.975	0.024
M24.94 Joint derangement, unspecified (Hand)	0.000	0.975	0.024
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.975	0.024
M34.0 Progressive systemic sclerosis	0.000	0.975	0.024
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.975	0.024
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.976	0.024
M24.68 Ankylosis of joint (Other)	0.000	0.976	0.024
M24.63 Ankylosis of joint (Forearm)	0.000	0.976	0.024
M24.62 Ankylosis of joint (Upper arm)	0.000	0.976	0.024
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.976	0.024
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.976	0.024
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.976	0.024
M24.98 Joint derangement, unspecified (Other)	0.000	0.976	0.024
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.976	0.024
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.976	0.024
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.976	0.024
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.976	0.024
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.976	0.024
M21.0 Valgus deformity, not elsewhere classified	0.000	0.976	0.024
M34.9 Systemic sclerosis, unspecified	0.000	0.976	0.024
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.976	0.024
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.976	0.024
M24.64 Ankylosis of joint (Hand)	0.000	0.976	0.024
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.976	0.024
M24.18 Other articular cartilage disorders (Other)	0.000	0.976	0.024
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.976	0.024
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.976	0.024
M24.21 Disorder of ligament (Shoulder region)	0.000	0.976	0.024
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.976	0.023
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.976	0.023
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.976	0.023
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.977	0.023
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.977	0.023
M24.29 Disorder of ligament (Site unspecified)	0.000	0.977	0.023
M24.22 Disorder of ligament (Upper arm)	0.000	0.977	0.023
M24.20 Disorder of ligament (Multiple sites)	0.000	0.977	0.023
M24.24 Disorder of ligament (Hand)	0.000	0.977	0.023
M24.14 Other articular cartilage disorders (Hand)	0.000	0.977	0.023
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.977	0.023
M35.3 Polymyalgia rheumatica	0.000	0.977	0.023
M31 Other necrotising vasculopathies	0.000	0.977	0.022
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.977	0.022
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.977	0.022
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.978	0.022
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.978	0.022
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.978	0.022
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.978	0.022
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.978	0.022
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.978	0.022
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.978	0.022
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.978	0.022
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.978	0.022
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.978	0.022
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.978	0.022
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.978	0.022
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.978	0.022
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.978	0.022
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.978	0.022
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.978	0.022
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.978	0.021
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.979	0.021
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.979	0.021
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.979	0.021
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.979	0.021
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.979	0.021
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.979	0.021
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.979	0.021
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.979	0.021
M24.23 Disorder of ligament (Forearm)	0.000	0.979	0.021
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.979	0.021
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.979	0.021
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.979	0.021
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.979	0.021
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.979	0.021
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.979	0.021
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.979	0.021
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.979	0.021
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.979	0.021
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.979	0.021
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.979	0.021
M24.26 Disorder of ligament (Lower leg)	0.000	0.979	0.020
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.979	0.020
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.979	0.020
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.979	0.020
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.979	0.020
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.979	0.020
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.979	0.020
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.979	0.020
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.979	0.020
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.979	0.020
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.980	0.020
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.980	0.020
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.980	0.020
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.980	0.020
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.980	0.020
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.980	0.020
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.980	0.020
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.980	0.020
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.980	0.020
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.980	0.020
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.980	0.020
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.980	0.019
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.981	0.019
M21.78 Unequal limb length (acquired)-Other	0.000	0.981	0.019
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.981	0.019
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.981	0.019
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.981	0.019
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.981	0.019
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.981	0.019
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.981	0.019
M21.24 Flexion deformity (Hand)	0.000	0.981	0.019
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.981	0.019
M21.23 Flexion deformity (Forearm)	0.000	0.981	0.018
M21.27 Flexion deformity (Ankle and foot)	0.000	0.981	0.018
M21.29 Flexion deformity (Site unspecified)	0.000	0.981	0.018
M21.28 Flexion deformity (Other)	0.000	0.981	0.018
M21.21 Flexion deformity (Shoulder region)	0.000	0.981	0.018
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.982	0.018
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.982	0.018
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.982	0.018
M21.20 Flexion deformity (Multiple sites)	0.000	0.982	0.018
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.982	0.018
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.982	0.018
M21.22 Flexion deformity (Upper arm)	0.000	0.982	0.018
K70 Alcoholic liver disease	0.018	0.982	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.982	0.017
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.982	0.017
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.982	0.017
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.982	0.017
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.982	0.017
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.982	0.017
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.982	0.017
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.982	0.017
K70.3 Alcoholic cirrhosis of liver	0.018	0.982	0.000
K70.9 Alcoholic liver disease, unspecified	0.017	0.983	0.000
M31.0 Hypersensitivity angiitis	0.000	0.983	0.017
M31.9 Necrotising vasculopathy, unspecified	0.000	0.983	0.017
M21.26 Flexion deformity (Lower leg)	0.000	0.983	0.017
M31.1 Thrombotic microangiopathy	0.000	0.983	0.016
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.983	0.016
M31.2 Lethal midline granuloma	0.000	0.983	0.016
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.983	0.016
M31.8 Other specified necrotising vasculopathies	0.000	0.984	0.016
M31.7 Microscopic polyangiitis	0.000	0.984	0.015
K70-K77 Diseases of liver	0.016	0.984	0.000
M31.3 Wegener's granulomatosis	0.000	0.985	0.015
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.985	0.015
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.985	0.014
K75 Other inflammatory liver diseases	0.014	0.985	0.000
K70.0 Alcoholic fatty liver	0.014	0.986	0.000
K74 Fibrosis and cirrhosis of liver	0.014	0.986	0.000
K76 Other diseases of liver	0.013	0.987	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.013	0.987	0.000
K75.4 Autoimmune hepatitis	0.013	0.987	0.000
K71 Toxic liver disease	0.013	0.987	0.000
K76.6 Portal hypertension	0.013	0.987	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.013	0.987	0.000
K74.3 Primary biliary cirrhosis	0.012	0.988	0.000
K75.0 Abscess of liver	0.012	0.988	0.000
K70.4 Alcoholic hepatic failure	0.012	0.988	0.000
K70.1 Alcoholic hepatitis	0.012	0.988	0.000
K74.6 Other and unspecified cirrhosis of liver	0.011	0.989	0.000
K72 Hepatic failure, not elsewhere classified	0.011	0.989	0.000
K75.8 Other specified inflammatory liver diseases	0.011	0.989	0.000
K73 Chronic hepatitis, not elsewhere classified	0.011	0.989	0.000
K77 Liver disorders in diseases classified elsewhere	0.011	0.989	0.000
K75.2 Nonspecific reactive hepatitis	0.011	0.989	0.000
K75.1 Phlebitis of portal vein	0.011	0.989	0.000
K74.5 Biliary cirrhosis, unspecified	0.010	0.990	0.000
K74.4 Secondary biliary cirrhosis	0.010	0.990	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.010	0.990	0.000
K74.1 Hepatic sclerosis	0.010	0.990	0.000
C44.6 Skin of upper limb, including shoulder	0.010	0.990	0.000
K74.0 Hepatic fibrosis	0.010	0.990	0.000
K75.9 Inflammatory liver disease, unspecified	0.010	0.990	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.010	0.990	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.010	0.990	0.000
K76.5 Hepatic veno-occlusive disease	0.010	0.990	0.000
K76.4 Peliosis hepatis	0.010	0.990	0.000
K76.2 Central haemorrhagic necrosis of liver	0.010	0.990	0.000
K72.9 Hepatic failure, unspecified	0.010	0.990	0.000
K71.9 Toxic liver disease, unspecified	0.010	0.990	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.010	0.990	0.000
K76.3 Infarction of liver	0.010	0.990	0.000
K76.1 Chronic passive congestion of liver	0.010	0.990	0.000
K71.0 Toxic liver disease with cholestasis	0.009	0.990	0.000
K71.8 Toxic liver disease with other disorders of liver	0.009	0.991	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.009	0.991	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.009	0.991	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.009	0.991	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.009	0.991	0.000
K71.2 Toxic liver disease with acute hepatitis	0.009	0.991	0.000
K76.9 Liver disease, unspecified	0.009	0.991	0.000
D50.8 Other iron deficiency anaemias	0.009	0.991	0.000
M31.6 Other giant cell arteritis	0.001	0.991	0.008
K76.7 Hepatorenal syndrome	0.008	0.991	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.008	0.992	0.000
M25 Other joint disorders, not elsewhere classified	0.000	0.992	0.008
K72.1 Chronic hepatic failure	0.008	0.992	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.008	0.992	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.008	0.992	0.000
M25.0 Haemarthrosis	0.000	0.992	0.008
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
K73.9 Chronic hepatitis, unspecified	0.007	0.992	0.000
M25.06 Haemarthrosis (Lower leg)	0.000	0.992	0.008
K77.8 Liver disorders in other diseases classified elsewhere	0.007	0.993	0.000
N40 Hyperplasia of prostate	0.007	0.993	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.007	0.993	0.000
M25.2 Flail joint	0.000	0.994	0.006
M25.1 Fistula of joint	0.000	0.994	0.006
K72.0 Acute and subacute hepatic failure	0.006	0.994	0.000
M25.3 Other instability of joint	0.000	0.994	0.006
M25.09 Haemarthrosis (Site unspecified)	0.000	0.994	0.006
M25.08 Haemarthrosis (Other)	0.000	0.994	0.006
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.994	0.006
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.994	0.006
M25.04 Haemarthrosis (Hand)	0.000	0.994	0.006
M25.03 Haemarthrosis (Forearm)	0.000	0.994	0.006
M25.02 Haemarthrosis (Upper arm)	0.000	0.994	0.006
M25.01 Haemarthrosis (Shoulder region)	0.000	0.994	0.006
M25.00 Haemarthrosis (Multiple sites)	0.000	0.994	0.006
Z09.8 Follow-up examination after other treatment for other conditions	0.006	0.994	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.994	0.006
C79.8 Secondary malignant neoplasm of other specified sites	0.006	0.994	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.006	0.994	0.000
E14.9 Without complications	0.006	0.994	0.000
M25.9 Joint disorder, unspecified	0.000	0.995	0.005
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.005	0.995	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.005	0.995	0.000
C79 Secondary malignant neoplasm of other sites	0.005	0.995	0.000
M25.34 Other instability of joint (Hand)	0.000	0.995	0.005
M25.19 Fistula of joint (Site unspecified)	0.000	0.995	0.005
M25.18 Fistula of joint (Other)	0.000	0.995	0.005
M25.17 Fistula of joint (Ankle and foot)	0.000	0.995	0.005
M25.16 Fistula of joint (Lower leg)	0.000	0.995	0.005
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.995	0.005
M25.14 Fistula of joint (Hand)	0.000	0.995	0.005
M25.13 Fistula of joint (Forearm)	0.000	0.995	0.005
M25.12 Fistula of joint (Upper arm)	0.000	0.995	0.005
M25.11 Fistula of joint (Shoulder region)	0.000	0.995	0.005
M25.10 Fistula of joint (Multiple sites)	0.000	0.995	0.005
M25.29 Flail joint (Site unspecified)	0.000	0.995	0.005
M25.28 Flail joint (Other)	0.000	0.995	0.005
M25.27 Flail joint (Ankle and foot)	0.000	0.995	0.005
M25.26 Flail joint (Lower leg)	0.000	0.995	0.005
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.995	0.005
M25.24 Flail joint (Hand)	0.000	0.995	0.005
M25.23 Flail joint (Forearm)	0.000	0.995	0.005
M25.22 Flail joint (Upper arm)	0.000	0.995	0.005
M25.21 Flail joint (Shoulder region)	0.000	0.995	0.005
M25.20 Flail joint (Multiple sites)	0.000	0.995	0.005
M25.7 Osteophyte	0.000	0.995	0.005
E14 Unspecified diabetes mellitus	0.005	0.995	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.005	0.995	0.000
Z72.0 Tobacco use	0.005	0.995	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.995	0.005
E14.3 With ophthalmic complications	0.005	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.000	0.995	0.004
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.005	0.995	0.000
M25.39 Other instability of joint (Site unspecified)	0.000	0.995	0.004
M25.38 Other instability of joint (Other)	0.000	0.995	0.004
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.995	0.004
M25.32 Other instability of joint (Upper arm)	0.000	0.995	0.004
M25.30 Other instability of joint (Multiple sites)	0.000	0.995	0.004
M25.36 Other instability of joint (Lower leg)	0.000	0.995	0.004
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.005	0.995	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.995	0.004
R26.8 Other and unspecified abnormalities of gait and mobility	0.005	0.995	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.996	0.004
R39.1 Other difficulties with micturition	0.004	0.996	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.996	0.004
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.004	0.996	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.996	0.004
M25.71 Osteophyte (Shoulder region)	0.000	0.996	0.004
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
R12 Heartburn	0.000	0.996	0.004
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
M25.8 Other specified joint disorders	0.000	0.996	0.004
M25.4 Effusion of joint	0.000	0.996	0.004
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.996	0.004
M25.31 Other instability of joint (Shoulder region)	0.000	0.996	0.004
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.996	0.004
C79.7 Secondary malignant neoplasm of adrenal gland	0.004	0.996	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.004	0.996	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.004	0.996	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M25.94 Joint disorder, unspecified (Hand)	0.000	0.996	0.004
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.996	0.004
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.996	0.004
M25.37 Other instability of joint (Ankle and foot)	0.000	0.996	0.004
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.996	0.004
M25.98 Joint disorder, unspecified (Other)	0.000	0.996	0.004
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.996	0.004
Z09.3 Follow-up examination after psychotherapy	0.004	0.996	0.000
C79.2 Secondary malignant neoplasm of skin	0.004	0.996	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.996	0.004
H00.1 Chalazion	0.000	0.996	0.004
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.996	0.004
Z09.1 Follow-up examination after radiotherapy for other conditions	0.004	0.996	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.996	0.004
E14.5 With peripheral circulatory complications	0.004	0.996	0.000
Z09.4 Follow-up examination after treatment of fracture	0.004	0.996	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.004	0.996	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
E14.0 With coma	0.004	0.996	0.000
E14.4 With neurological complications	0.004	0.996	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.004	0.996	0.000
Z73 Problems related to life-management difficulty	0.004	0.996	0.000
Z72 Problems related to lifestyle	0.004	0.996	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.996	0.004
M25.70 Osteophyte (Multiple sites)	0.000	0.996	0.004
E14.7 With multiple complications	0.004	0.996	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.996	0.003
E14.6 With other specified complications	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
E14.2 Withrenal complications	0.004	0.996	0.000
Z01.8 Other specified special examinations	0.004	0.996	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.996	0.004
M25.44 Effusion of joint (Hand)	0.000	0.996	0.003
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.996	0.003
M25.83 Other specified joint disorders (Forearm)	0.000	0.996	0.003
E14.1 With ketoacidosis	0.003	0.996	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.996	0.003
Z09.0 Follow-up examination after surgery for other conditions	0.004	0.996	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.004	0.996	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.997	0.003
M25.73 Osteophyte (Forearm)	0.000	0.997	0.003
Z71.9 Counselling, unspecified	0.003	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.997	0.003
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.997	0.003
Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
M25.49 Effusion of joint (Site unspecified)	0.000	0.997	0.003
M25.48 Effusion of joint (Other)	0.000	0.997	0.003
Z75 Problems related to medical facilities and other health care	0.003	0.997	0.000
H36.0 Diabetic retinopathy	0.003	0.997	0.000
R26 Abnormalities of gait and mobility	0.003	0.997	0.000
C79.6 Secondary malignant neoplasm of ovary	0.003	0.997	0.000
E14.8 With unspecified complications	0.003	0.997	0.000
Z74 Problems related to care-provider dependency	0.003	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.000	0.997	0.003
Z72.2 Drug use	0.003	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.997	0.003
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.000	0.997	0.003
R26.2 Difficulty in walking, not elsewhere classified	0.003	0.997	0.000
Z72.8 Other problems related to lifestyle	0.003	0.997	0.000
M25.42 Effusion of joint (Upper arm)	0.000	0.997	0.003
Z73.6 Limitation of activities due to disability	0.003	0.997	0.000
Z90.2 Acquired absence of lung [part of]	0.003	0.997	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations