TreeWAS – Variant ID: rs4459386

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.000	1.000
D12.5 Sigmoid colon	0.000	0.000	1.000
D12.3 Transverse colon	0.000	0.000	1.000
D12.2 Ascending colon	0.000	0.002	0.998
D12.4 Descending colon	0.000	0.025	0.975
D12.8 Rectum	0.000	0.045	0.955
I10 Essential (primary) hypertension	0.938	0.062	0.000
D12.7 Rectosigmoid junction	0.000	0.154	0.846
D12.0 Caecum	0.000	0.257	0.743
D12.1 Appendix	0.000	0.360	0.640
D12.9 Anus and anal canal	0.000	0.551	0.449
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.697	0.303
D12.6 Colon, unspecified	0.000	0.717	0.283
I10-I15 Hypertensive diseases	0.185	0.815	0.000
I13 Hypertensive heart and renal disease	0.133	0.867	0.000
I11 Hypertensive heart disease	0.124	0.876	0.000
I83 Varicose veins of lower extremities	0.000	0.877	0.123
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.895	0.104
I15 Secondary hypertension	0.102	0.897	0.000
I12 Hypertensive renal disease	0.101	0.899	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.095	0.905	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.095	0.905	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.095	0.905	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.095	0.905	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.087	0.912	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.913	0.087
I12.9 Hypertensive renal disease without renal failure	0.083	0.917	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.082	0.917	0.000
I15.1 Hypertension secondary to other renal disorders	0.082	0.918	0.000
I15.8 Other secondary hypertension	0.074	0.926	0.000
I15.2 Hypertension secondary to endocrine disorders	0.070	0.929	0.000
I15.0 Renovascular hypertension	0.063	0.936	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.941	0.059
I15.9 Seconday hypertension, unspecified	0.048	0.951	0.001
Y83.1 Surgical operation with implant of artificial internal device	0.021	0.979	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.020	0.980	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.017	0.983	0.000
Z97 Presence of other devices	0.016	0.984	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.985	0.015
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.985	0.015
Z97.4 Presence of external hearing-aid	0.014	0.986	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.986	0.014
Z97.3 Presence of spectacles and contact lenses	0.013	0.987	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.013	0.987	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.012	0.988	0.000
D63.0 Anaemia in neoplastic disease	0.012	0.988	0.000
Z97.8 Presence of other specified devices	0.012	0.988	0.000
Z97.0 Presence of artificial eye	0.012	0.988	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.991	0.009
D22.1 Melanocytic naevi of eyelid, including canthus	0.009	0.991	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.991	0.009
D22.0 Melanocytic naevi of lip	0.009	0.991	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.991	0.009
O75.0 Maternal distress during labour and delivery	0.000	0.991	0.009
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
G56.0 Carpal tunnel syndrome	0.000	0.992	0.008
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.008	0.992	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.992	0.008
X63.0 Home	0.008	0.992	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.992	0.008
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.992	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.992	0.000
T44.0 Anticholinesterase agents	0.007	0.992	0.000
A49.8 Other bacterial infections of unspecified site	0.007	0.993	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.993	0.007
O75.9 Complication of labour and delivery, unspecified	0.000	0.993	0.007
O75.4 Other complications of obstetric surgery and procedures	0.000	0.993	0.007
O75.1 Shock during or following labour and delivery	0.000	0.993	0.007
M75.3 Calcific tendinitis of shoulder	0.000	0.993	0.007
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.993	0.007
D22.7 Melanocytic naevi of lower limb, including hip	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.007	0.993	0.000
G25.0 Essential tremor	0.007	0.993	0.000
D22 Melanocytic naevi	0.007	0.993	0.000
I84.2 Internal haemorrhoids without complication	0.007	0.993	0.000
G25 Other extrapyramidal and movement disorders	0.006	0.994	0.000
G25.3 Myoclonus	0.006	0.994	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.006	0.994	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.994	0.006
D61.9 Aplastic anaemia, unspecified	0.006	0.994	0.000
O75.3 Other infection during labour	0.000	0.994	0.006
G25.2 Other specified forms of tremor	0.006	0.994	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.994	0.006
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.994	0.006
Z88.4 Personal history of allergy to anaesthetic agent	0.006	0.994	0.000
G25.1 Drug-induced tremor	0.005	0.995	0.000
H53.8 Other visual disturbances	0.005	0.995	0.000
D22.9 Melanocytic naevi, unspecified	0.005	0.995	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.995	0.005
G20-G26 Extrapyramidal and movement disorders	0.005	0.995	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
G25.5 Other chorea	0.005	0.995	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.005	0.995	0.000
G25.4 Drug-induced chorea	0.005	0.995	0.000
N18.2 Chronic kidney disease, stage 2	0.005	0.995	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.995	0.005
G20 Parkinson's disease	0.005	0.995	0.000
G24 Dystonia	0.004	0.996	0.000
G23 Other degenerative diseases of basal ganglia	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.004	0.996	0.000
D61 Other aplastic anaemias	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.996	0.004
L08 Other local infections of skin and subcutaneous tissue	0.000	0.996	0.004
S62.50 Fracture of thumb (closed)	0.004	0.996	0.000
H53.0 Amblyopia ex anopsia	0.000	0.996	0.004
G21 Secondary Parkinsonism	0.004	0.996	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.004	0.996	0.000
G22 Parkinsonism in diseases classified elsewhere	0.004	0.996	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
G24.0 Drug-induced dystonia	0.004	0.996	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.004	0.996	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.004	0.996	0.000
G24.3 Spasmodic torticollis	0.004	0.996	0.000
A49.1 Streptococcal infection, unspecified	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.996	0.004
G24.8 Other dystonia	0.004	0.996	0.000
A49 Bacterial infection of unspecified site	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.003	0.997	0.000
G24.4 Idiopathic orofacial dystonia	0.003	0.997	0.000
G24.2 Idiopathic nonfamilial dystonia	0.003	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
N90.5 Atrophy of vulva	0.000	0.997	0.003
G24.5 Blepharospasm	0.003	0.997	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.003	0.997	0.000
G23.3 Multiple system atrophy, cerebellar type	0.003	0.997	0.000
G23.2 Striatonigral degeneration	0.003	0.997	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.003	0.997	0.000
G23.0 Hallervorden-Spatz disease	0.003	0.997	0.000
G24.1 Idiopathic familial dystonia	0.003	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.997	0.003
L08.0 Pyoderma	0.000	0.997	0.003
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M79.0 Rheumatism, unspecified	0.000	0.997	0.003
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.997	0.003
M24.0 Loose body in joint	0.003	0.997	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.997	0.003
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.997	0.003
D61.1 Drug-induced aplastic anaemia	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.997	0.003
L08.1 Erythrasma	0.000	0.997	0.003
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
G21.9 Secondary Parkinsonism, unspecified	0.003	0.997	0.000
G21.8 Other secondary Parkinsonism	0.003	0.997	0.000
G21.4 Vascular parkinsonism	0.003	0.997	0.000
G21.3 Postencephalitic Parkinsonism	0.003	0.997	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.003	0.997	0.000
G21.0 Malignant neuroleptic syndrome	0.003	0.997	0.000
X63.9 Unspecified place	0.003	0.997	0.000
X63.8 Other specified place	0.003	0.997	0.000
X63.7 Farm	0.003	0.997	0.000
X63.6 Industrial and construction area	0.003	0.997	0.000
X63.5 Trade and service area	0.003	0.997	0.000
X63.4 Street and highway	0.003	0.997	0.000
X63.3 Sports and athletics area	0.003	0.997	0.000
X63.2 School, other institution and public administrative area	0.003	0.997	0.000
X63.1 Residential institution	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
M81.9 Osteoporosis, unspecified	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.997	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.003	0.997	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.000	0.997	0.003
A49.3 Mycoplasma infection, unspecified	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.003	0.997	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.003	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
K61.0 Anal abscess	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
Z93.2 Ileostomy status	0.000	0.997	0.003
M79.07 Rheumatism, unspecified (Ankle and foot)	0.000	0.997	0.002
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
M79.04 Rheumatism, unspecified (Hand)	0.000	0.997	0.002
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.997	0.002
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.997	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.002	0.997	0.000
M24.08 Loose body in joint (Other)	0.002	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.997	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.997	0.000
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.997	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.000	0.997	0.002
X63.99 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system; Unspecified place ;During unspecified activity	0.002	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.000	0.998	0.002
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
Z93.8 Other artificial opening status	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.998	0.002
N90.1 Moderate vulvar dysplasia	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
S62.5 Fracture of thumb	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
M79.08 Rheumatism, unspecified (Other)	0.000	0.998	0.002
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
N90.6 Hypertrophy of vulva	0.000	0.998	0.002
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
Z93.9 Artificial opening status, unspecified	0.000	0.998	0.002
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
K90.0 Coeliac disease	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
I87.1 Compression of vein	0.000	0.998	0.002
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.000	0.998	0.002
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
I87 Other disorders of veins	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
N90.3 Dysplasia of vulva, unspecified	0.000	0.998	0.002
M24.79 Protrusio acetabuli-Site unspec	0.001	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
Y83.0 Surgical operation with transplant of whole organ	0.002	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
K90.8 Other intestinal malabsorption	0.000	0.998	0.002
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.998	0.002
R60.1 Generalised oedema	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M54.1 Radiculopathy	0.002	0.998	0.000
N90.0 Mild vulvar dysplasia	0.000	0.998	0.002
Q44.6 Cystic disease of liver	0.002	0.998	0.000
R18 Ascites	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.002	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
W20.8 Other specified place	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.002	0.998	0.000
O02 Other abnormal products of conception	0.000	0.998	0.002
Z93 Artificial opening status	0.000	0.998	0.002
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
Z93.3 Colostomy status	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
K12.1 Other forms of stomatitis	0.000	0.998	0.002
O61.0 Failed medical induction of labour	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
K90 Intestinal malabsorption	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
K90.9 Intestinal malabsorption, unspecified	0.000	0.998	0.002
R06.4 Hyperventilation	0.002	0.998	0.000
T00.9 Multiple superficial injuries, unspecified	0.000	0.998	0.002
Z93.6 Other artificial openings of urinary tract status	0.000	0.998	0.002
I87.0 Postphlebitic syndrome	0.000	0.998	0.001
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.001	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
T02.50 Fractures involving multiple regions of both lower limbs (closed)	0.000	0.998	0.001
O02.1 Missed abortion	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.002	0.998	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.000	0.998	0.001
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
T00 Superficial injuries involving multiple body regions	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.001	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.001	0.998	0.001
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.002
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.998	0.001
M54.15 Radiculopathy (Thoracolumbar region)	0.001	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.001	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.001	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.001	0.998	0.000
W20.0 Home	0.000	0.998	0.001
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.001
S72.21 Subtrochanteric fracture (open)	0.001	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
M81.8 Other osteoporosis	0.001	0.998	0.000
T02.5 Fractures involving multiple regions of both lower limbs	0.000	0.998	0.001
B16 Acute hepatitis B	0.000	0.998	0.001
D29.1 Prostate	0.001	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.001
O02.8 Other specified abnormal products of conception	0.000	0.998	0.001
W25 Contact with sharp glass	0.000	0.998	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.001	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.001	0.998	0.000
I87.8 Other specified disorders of veins	0.000	0.998	0.001
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.001
S73.1 Sprain and strain of hip	0.001	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
D22.5 Melanocytic naevi of trunk	0.001	0.999	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.999	0.001
K90.3 Pancreatic steatorrhoea	0.000	0.999	0.001
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.999	0.001
K90.1 Tropical sprue	0.000	0.999	0.001
T02 Fractures involving multiple body regions	0.000	0.999	0.001
M23.49 Loose body in knee-Unspec lig/men	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
V19.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
Z98.1 Arthrodesis status	0.001	0.999	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.999	0.000
W45.6 Industrial and construction area	0.000	0.999	0.001
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.999	0.001
G43.1 Migraine with aura [classical migraine]	0.000	0.999	0.001
G95.8 Other specified diseases of spinal cord	0.000	0.999	0.001
G96.8 Other specified disorders of central nervous system	0.001	0.999	0.000
K12.0 Recurrent oral aphthae	0.000	0.999	0.001
K14.0 Glossitis	0.000	0.999	0.001
S32.4 Fracture of acetabulum	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
W20 Struck by thrown, projected or falling object	0.000	0.999	0.001
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
M81.6 Localised osteoporosis [Lequesne]	0.001	0.999	0.000
M81.5 Idiopathic osteoporosis	0.001	0.999	0.000
M81.1 Postoophorectomy osteoporosis	0.001	0.999	0.000
N80.3 Endometriosis of pelvic peritoneum	0.001	0.999	0.000
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.000	0.999	0.001
T00.0 Superficial injuries involving head with neck	0.000	0.999	0.001
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.999	0.001
F52.2 Failure of genital response	0.001	0.999	0.000
K60.3 Anal fistula	0.001	0.999	0.000
W26.8 Other specified place	0.000	0.999	0.001
M81.89 Other osteoporosis (Site unspecified)	0.001	0.999	0.000
M81.88 Other osteoporosis (Other)	0.001	0.999	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.001	0.999	0.000
M81.86 Other osteoporosis (Lower leg)	0.001	0.999	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.001	0.999	0.000
M81.84 Other osteoporosis (Hand)	0.001	0.999	0.000
M81.83 Other osteoporosis (Forearm)	0.001	0.999	0.000
M81.82 Other osteoporosis (Upper arm)	0.001	0.999	0.000
M81.81 Other osteoporosis (Shoulder region)	0.001	0.999	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.999	0.000
T02.51 Fractures involving multiple regions of both lower limbs (open)	0.000	0.999	0.001
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.999	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.999	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.999	0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.999	0.001
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.999	0.000
T00.8 Superficial injuries involving other combinations of body regions	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.001	0.999	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.001	0.999	0.000
S73.0 Dislocation of hip	0.001	0.999	0.000
T92.1 Sequelae of fracture of arm	0.000	0.999	0.001
W25.6 Industrial and construction area	0.000	0.999	0.001
W25.5 Trade and service area	0.000	0.999	0.001
W25.1 Residential institution	0.000	0.999	0.001
W25.0 Home	0.000	0.999	0.001
W25.8 Other specified place	0.000	0.999	0.001
W25.7 Farm	0.000	0.999	0.001
W25.4 Street and highway	0.000	0.999	0.001
W25.3 Sports and athletics area	0.000	0.999	0.001
W25.2 School, other institution and public administrative area	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations