TreeWAS – Variant ID: rs4468878

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K51.9 Ulcerative colitis, unspecified	0.000	0.469	0.531
K51 Ulcerative colitis	0.000	0.614	0.386
K51.4 Pseudopolyposis of colon	0.000	0.626	0.374
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.672	0.328
K51.8 Other ulcerative colitis	0.000	0.705	0.295
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.725	0.275
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.741	0.259
K51.5 Mucosal proctocolitis	0.000	0.800	0.200
K51.2 Ulcerative (chronic) proctitis	0.000	0.907	0.093
E04.1 Non-toxic single thyroid nodule	0.000	0.920	0.080
E89.0 Postprocedural hypothyroidism	0.043	0.957	0.000
E04 Other non-toxic goitre	0.000	0.963	0.037
E04.2 Non-toxic multinodular goitre	0.000	0.964	0.036
E04.8 Other specified non-toxic goitre	0.000	0.973	0.027
K50-K52 Noninfective enteritis and colitis	0.000	0.973	0.027
D22.7 Melanocytic naevi of lower limb, including hip	0.025	0.975	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.978	0.022
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.980	0.020
Q63.0 Accessory kidney	0.018	0.982	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.018	0.982	0.000
J18.1 Lobar pneumonia, unspecified	0.016	0.984	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.016	0.984	0.000
S42.10 Fracture of scapula (closed)	0.000	0.985	0.015
E89.3 Postprocedural hypopituitarism	0.014	0.986	0.000
N87.0 Mild cervical dysplasia	0.000	0.986	0.014
S42.1 Fracture of scapula	0.000	0.987	0.013
J18 Pneumonia, organism unspecified	0.013	0.987	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.988	0.012
J15 Bacterial pneumonia, not elsewhere classified	0.012	0.988	0.000
J09-J18 Influenza and pneumonia	0.012	0.988	0.000
S42.4 Fracture of lower end of humerus	0.000	0.988	0.012
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.011	0.989	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.011	0.989	0.000
E89.5 Postprocedural testicular hypofunction	0.011	0.989	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.011	0.989	0.000
E89.4 Postprocedural ovarian failure	0.011	0.989	0.000
J15.2 Pneumonia due to staphylococcus	0.011	0.989	0.000
J18.8 Other pneumonia, organism unspecified	0.011	0.989	0.000
S42 Fracture of shoulder and upper arm	0.000	0.989	0.011
J13 Pneumonia due to Streptococcus pneumoniae	0.011	0.989	0.000
J15.1 Pneumonia due to Pseudomonas	0.011	0.989	0.000
J10 Influenza due to identified influenza virus	0.011	0.989	0.000
E89.1 Postprocedural hypoinsulinaemia	0.010	0.989	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.989	0.010
S40 Superficial injury of shoulder and upper arm	0.000	0.990	0.010
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.010	0.990	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.010	0.990	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.990	0.010
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.990	0.010
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.010	0.990	0.000
J18.2 Hypostatic pneumonia, unspecified	0.009	0.990	0.000
J15.5 Pneumonia due to Escherichia coli	0.009	0.991	0.000
S42.11 Fracture of scapula (open)	0.000	0.991	0.009
J15.8 Other bacterial pneumonia	0.009	0.991	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.991	0.009
Z73.3 Stress, not elsewhere classified	0.009	0.991	0.000
J15.3 Pneumonia due to streptococcus, group B	0.009	0.991	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.991	0.009
J14 Pneumonia due to Haemophilus influenzae	0.009	0.991	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.991	0.009
D03.3 Melanoma in situ of other and unspecified parts of face	0.009	0.991	0.000
Q63 Other congenital malformations of kidney	0.009	0.991	0.000
J12 Viral pneumonia, not elsewhere classified	0.009	0.991	0.000
S42.0 Fracture of clavicle	0.000	0.991	0.009
O82.1 Delivery by emergency Caesarean section	0.009	0.991	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.009	0.991	0.000
J11 Influenza, virus not identified	0.009	0.991	0.000
J09 Influenza due to certain identified influenza virus	0.008	0.991	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.991	0.009
J10.0 Influenza with pneumonia, influenza virus identified	0.008	0.992	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.008	0.992	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.992	0.008
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.992	0.008
J10.8 Influenza with other manifestations, influenza virus identified	0.008	0.992	0.000
E89.2 Postprocedural hypoparathyroidism	0.008	0.992	0.000
J12.9 Viral pneumonia, unspecified	0.008	0.992	0.000
J18.0 Bronchopneumonia, unspecified	0.008	0.992	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.992	0.008
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.992	0.007
N80.9 Endometriosis, unspecified	0.007	0.993	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.007	0.993	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.007	0.993	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.993	0.007
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.993	0.007
S42.00 Fracture of clavicle (closed)	0.000	0.993	0.007
J11.8 Influenza with other manifestations, virus not identified	0.007	0.993	0.000
J15.9 Bacterial pneumonia, unspecified	0.007	0.993	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.007	0.993	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.993	0.007
S48 Traumatic amputation of shoulder and upper arm	0.000	0.993	0.007
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.993	0.007
S47 Crushing injury of shoulder and upper arm	0.000	0.993	0.007
S22.30 Fracture of rib (closed)	0.000	0.993	0.007
Q63.3 Hyperplastic and giant kidney	0.006	0.993	0.000
J12.8 Other viral pneumonia	0.006	0.993	0.000
J12.3 Human metapneumovirus pneumonia	0.006	0.993	0.000
J12.0 Adenoviral pneumonia	0.006	0.993	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.993	0.007
S42.01 Fracture of clavicle (open)	0.000	0.993	0.006
J16.0 Chlamydial pneumonia	0.006	0.993	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.994	0.006
J16.8 Pneumonia due to other specified infectious organisms	0.006	0.994	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.006	0.994	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.006	0.994	0.000
Z73 Problems related to life-management difficulty	0.006	0.994	0.000
S44 Injury of nerves at shoulder and upper arm level	0.000	0.994	0.006
J11.0 Influenza with pneumonia, virus not identified	0.006	0.994	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.006	0.994	0.000
Z73.6 Limitation of activities due to disability	0.006	0.994	0.000
Q63.8 Other specified congenital malformations of kidney	0.006	0.994	0.000
Q63.2 Ectopic kidney	0.006	0.994	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.994	0.006
Z73.8 Other problems related to life-management difficulty	0.006	0.994	0.000
M54.4 Lumbago with sciatica	0.006	0.994	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.994	0.006
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.994	0.006
J12.1 Respiratory syncytial virus pneumonia	0.006	0.994	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.994	0.006
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.994	0.006
M54.49 Lumbago with sciatica (Site unspecified)	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.994	0.006
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
S42.2 Fracture of upper end of humerus	0.000	0.994	0.006
S41 Open wound of shoulder and upper arm	0.000	0.994	0.006
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.994	0.005
S46.3 Injury of muscle and tendon of triceps	0.000	0.994	0.005
J15.4 Pneumonia due to other streptococci	0.005	0.994	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.995	0.005
G04 Encephalitis, myelitis and encephalomyelitis	0.005	0.995	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.005	0.995	0.000
G62.9 Polyneuropathy, unspecified	0.005	0.995	0.000
J12.2 Parainfluenza virus pneumonia	0.005	0.995	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.995	0.005
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.000	0.995	0.005
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.000	0.995	0.005
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.000	0.995	0.005
S45.3 Injury of superficial vein at shoulder and upper arm level	0.000	0.995	0.005
S45.2 Injury of axillary or brachial vein	0.000	0.995	0.005
S45.1 Injury of brachial artery	0.000	0.995	0.005
S45.0 Injury of axillary artery	0.000	0.995	0.005
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.000	0.995	0.005
S48.1 Traumatic amputation at level between shoulder and elbow	0.000	0.995	0.005
S48.0 Traumatic amputation at shoulder joint	0.000	0.995	0.005
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.995	0.005
J17 Pneumonia in diseases classified elsewhere	0.004	0.995	0.000
Z73.5 Social role conflict, not elsewhere classified	0.005	0.995	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.005	0.995	0.000
Z73.2 Lack of relaxation and leisure	0.005	0.995	0.000
Z73.1 Accentuation of personality traits	0.005	0.995	0.000
Z73.0 Burn-out	0.005	0.995	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.000	0.995	0.004
S44.8 Injury of other nerves at shoulder and upper arm level	0.000	0.995	0.004
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.000	0.995	0.004
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.000	0.995	0.004
S44.4 Injury of musculocutaneous nerve	0.000	0.995	0.004
S44.3 Injury of axillary nerve	0.000	0.995	0.004
S44.1 Injury of median nerve at upper arm level	0.000	0.995	0.004
S44.0 Injury of ulnar nerve at upper arm level	0.000	0.995	0.004
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.005	0.995	0.000
S42.3 Fracture of shaft of humerus	0.000	0.995	0.005
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.005	0.995	0.000
M54.44 Lumbago with sciatica-Thoracic	0.005	0.995	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.005	0.995	0.000
M54.42 Lumbago with sciatica-Cervical	0.005	0.995	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.005	0.995	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.005	0.995	0.000
E85.4 Organ-limited amyloidosis	0.005	0.995	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.005	0.995	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.995	0.004
S41.1 Open wound of upper arm	0.000	0.995	0.004
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.995	0.004
G50.0 Trigeminal neuralgia	0.000	0.996	0.004
S41.7 Multiple open wounds of shoulder and upper arm	0.000	0.996	0.004
E85 Amyloidosis	0.004	0.996	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.996	0.004
S44.2 Injury of radial nerve at upper arm level	0.000	0.996	0.004
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.004	0.996	0.000
G04.1 Tropical spastic paraplegia	0.004	0.996	0.000
E85.9 Amyloidosis, unspecified	0.004	0.996	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.000	0.996	0.004
G04.0 Acute disseminated encephalitis	0.004	0.996	0.000
E85.3 Secondary systemic amyloidosis	0.004	0.996	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
D03 Melanoma in situ	0.004	0.996	0.000
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.003	0.996	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
E85.8 Other amyloidosis	0.004	0.996	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.996	0.004
S41.0 Open wound of shoulder	0.000	0.996	0.003
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
S22.3 Fracture of rib	0.000	0.996	0.004
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.997	0.003
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.997	0.003
E85.2 Heredofamilial amyloidosis, unspecified	0.003	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.003	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.003	0.997	0.000
G80 Infantile cerebral palsy	0.003	0.997	0.000
C44.0 Skin of lip	0.003	0.997	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.003	0.997	0.000
Z45.1 Adjustment and management of infusion pump	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
J17.2 Pneumonia in mycoses	0.003	0.997	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.003	0.997	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.997	0.003
R73.0 Abnormal glucose tolerance test	0.003	0.997	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
G80.1 Spastic diplegia	0.003	0.997	0.000
G80.8 Other infantile cerebral palsy	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
K52.3 Indeterminate colitis	0.000	0.997	0.003
M76.67 Achilles tendinitis (Ankle and foot)	0.003	0.997	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.997	0.003
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
G06.0 Intracranial abscess and granuloma	0.003	0.997	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.003	0.997	0.000
D03.9 Melanoma in situ, unspecified	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
G80.2 Infantile hemiplegia	0.003	0.997	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.997	0.003
S10.9 Superficial injury of neck, part unspecified	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.003
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.997	0.003
G00-G09 Inflammatory diseases of the central nervous system	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.003	0.997	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.997	0.003
E87.2 Acidosis	0.003	0.997	0.000
G61.8 Other inflammatory polyneuropathies	0.003	0.997	0.000
G80.4 Ataxic cerebral palsy	0.003	0.997	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
G62 Other polyneuropathies	0.003	0.997	0.000
J33.0 Polyp of nasal cavity	0.000	0.997	0.003
J17.3 Pneumonia in parasitic diseases	0.002	0.997	0.001
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.997	0.002
S06.00 Concussion (without open intracranial wound)	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
E70-E90 Metabolic disorders	0.003	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.997	0.000
T85.2 Mechanical complication of intraocular lens	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.997	0.000
T50.5 Appetite depressants	0.002	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.997	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.003	0.997	0.000
H04.2 Epiphora	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.002	0.998	0.000
E87.5 Hyperkalaemia	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
Z92.0 Personal history of contraception	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.002	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.998	0.000
N87 Dysplasia of cervix uteri	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
E84 Cystic fibrosis	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
E76 Disorders of glycosaminoglycan metabolism	0.002	0.998	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.002	0.998	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.002
G00.8 Other bacterial meningitis	0.002	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
C61 Malignant neoplasm of prostate	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.002	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
E74.0 Glycogen storage disease	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
E87.6 Hypokalaemia	0.002	0.998	0.000
E87.4 Mixed disorder of acid-base balance	0.002	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.000	0.998	0.002
G61.1 Serum neuropathy	0.002	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
M76.66 Achilles tendinitis (Lower leg)	0.002	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
F60.0 Paranoid personality disorder	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
E70 Disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
M76.69 Achilles tendinitis-Site unspec	0.002	0.998	0.000
M76.68 Achilles tendinitis-Other	0.002	0.998	0.000
M76.65 Achilles tendinitis-Pelvic/Thigh	0.002	0.998	0.000
M76.64 Achilles tendinitis-Hand	0.002	0.998	0.000
M76.63 Achilles tendinitis-Forearm	0.002	0.998	0.000
M76.62 Achilles tendinitis-Upper arm	0.002	0.998	0.000
M76.61 Achilles tendinitis-Shldr region	0.002	0.998	0.000
M76.60 Achilles tendinitis (Multiple sites)	0.002	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
M15.3 Secondary multiple arthrosis	0.002	0.998	0.000
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
G00.3 Staphylococcal meningitis	0.002	0.998	0.000
G00.0 Haemophilus meningitis	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G02.1 Meningitis in mycoses	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.002	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.002	0.998	0.000
E72.5 Disorders of glycine metabolism	0.002	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.002	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.002	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.002	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.002	0.998	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.002	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.002	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.002	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.998	0.002
E84.8 Cystic fibrosis with other manifestations	0.002	0.998	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.002	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.002	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.002	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.002	0.998	0.000
E71.0 Maple-syrup-urine disease	0.002	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.002	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.002	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.002	0.998	0.000
E75.2 Other sphingolipidosis	0.002	0.998	0.000
E75.1 Other gangliosidosis	0.002	0.998	0.000
E75.0 GM2 gangliosidosis	0.002	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.002	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.002	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.002	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.002	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.002	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
E75.5 Other lipid storage disorders	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.998	0.002
O97 Death from sequelae of direct obstetric causes	0.000	0.998	0.002
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.998	0.002
O95 Obstetric death of unspecified cause	0.000	0.998	0.002
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C11.9 Nasopharynx, unspecified	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.002	0.998	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.002	0.998	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.002	0.998	0.000
E74.2 Disorders of galactose metabolism	0.002	0.998	0.000
E74.1 Disorders of fructose metabolism	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
G03.8 Meningitis due to other specified causes	0.002	0.998	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.002	0.998	0.000
G03.1 Chronic meningitis	0.002	0.998	0.000
G03.0 Nonpyogenic meningitis	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
F60.5 Anankastic personality disorder	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.002
G35 Multiple sclerosis	0.000	0.998	0.002
G50 Disorders of trigeminal nerve	0.000	0.998	0.002
C67.0 Trigone of bladder	0.000	0.998	0.002
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.998	0.001
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
G62.1 Alcoholic polyneuropathy	0.001	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.001	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.001	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.001	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.001	0.998	0.000
E70.0 Classical phenylketonuria	0.001	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.998	0.000
S10.0 Contusion of throat	0.002	0.998	0.000
M76.56 Patellar tendinitis-Lower Leg	0.002	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.001	0.998	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.001	0.998	0.000
E79.1 Lesch-Nyhan syndrome	0.001	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.998	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.998	0.001
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.001	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M15 Polyarthrosis	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.998	0.001
M76.5 Patellar tendinitis	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.998	0.001
F45 Somatoform disorders	0.000	0.998	0.002
M76 Enthesopathies of lower limb, excluding foot	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.998	0.001
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.998	0.001
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.998	0.001
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.998	0.001
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.998	0.001
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.998	0.001
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.998	0.001
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.998	0.001
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.998	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.001	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
O96.9 Death from unspecified obstetric cause	0.000	0.998	0.001
O96.1 Death from indirect obstetric cause	0.000	0.998	0.001
O96.0 Death from direct obstetric cause	0.000	0.998	0.001
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.998	0.001
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.998	0.001
O97.0 Death from sequelae of direct obstetric cause	0.000	0.998	0.001
R45.2 Unhappiness	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations