TreeWAS – Variant ID: rs447

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.60 Fracture of lateral malleolus (closed)	0.042	0.958	0.000
S82.6 Fracture of lateral malleolus	0.027	0.973	0.000
S82.61 Fracture of lateral malleolus (open)	0.021	0.979	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.981	0.019
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.016	0.984	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.015	0.985	0.000
S80-S89 Injuries to the knee and lower leg	0.015	0.985	0.000
T42.1 Iminostilbenes	0.014	0.986	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.014	0.986	0.000
S82 Fracture of lower leg, including ankle	0.014	0.986	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.014	0.986	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.013	0.987	0.000
S50.9 Superficial injury of forearm, unspecified	0.013	0.987	0.000
S86 Injury of muscle and tendon at lower leg level	0.013	0.987	0.000
S50 Superficial injury of forearm	0.013	0.987	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.013	0.987	0.000
S81 Open wound of lower leg	0.013	0.987	0.000
S81.8 Open wound of other parts of lower leg	0.013	0.987	0.000
S50.0 Contusion of elbow	0.013	0.987	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
S82.1 Fracture of upper end of tibia	0.012	0.988	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.012	0.988	0.000
S89 Other and unspecified injuries of lower leg	0.012	0.988	0.000
T42.4 Benzodiazepines	0.012	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.011	0.989	0.000
T42.2 Succinimides and oxazolidinediones	0.011	0.989	0.000
S82.10 Fracture of upper end of tibia (closed)	0.011	0.989	0.000
S50.8 Other superficial injuries of forearm	0.011	0.989	0.000
T36 Poisoning by systemic antibiotics	0.011	0.989	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.011	0.989	0.000
S87 Crushing injury of lower leg	0.011	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.011	0.989	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.011	0.989	0.000
S85 Injury of blood vessels at lower leg level	0.011	0.989	0.000
S83.7 Injury to multiple structures of knee	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.011	0.989	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.011	0.989	0.000
S88 Traumatic amputation of lower leg	0.011	0.989	0.000
S84 Injury of nerves at lower leg level	0.011	0.989	0.000
S83.2 Tear of meniscus, current	0.011	0.989	0.000
T42.3 Barbiturates	0.011	0.989	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
S81.7 Multiple open wounds of lower leg	0.011	0.989	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.011	0.989	0.000
T47.4 Other laxatives	0.010	0.989	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.010	0.989	0.000
E87.6 Hypokalaemia	0.011	0.989	0.000
T47.2 Stimulant laxatives	0.010	0.989	0.000
S50-S59 Injuries to the elbow and forearm	0.011	0.989	0.000
S82.4 Fracture of fibula alone	0.010	0.989	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.010	0.990	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.010	0.990	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.010	0.990	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.990	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.990	0.000
T47.7 Emetics	0.010	0.990	0.000
T47.5 Digestants	0.010	0.990	0.000
T47.3 Saline and osmotic laxatives	0.010	0.990	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.010	0.990	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.010	0.990	0.000
T79-T79 Certain early complications of trauma	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
S70-S79 Injuries to the hip and thigh	0.010	0.990	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.010	0.990	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.010	0.990	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.010	0.990	0.000
T47.0 Histamine H(2)-receptor antagonists	0.010	0.990	0.000
S83.0 Dislocation of patella	0.010	0.990	0.000
S86.0 Injury of Achilles tendon	0.010	0.990	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.010	0.990	0.000
T42.0 Hydantoin derivatives	0.010	0.990	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.010	0.990	0.000
S89.8 Other specified injuries of lower leg	0.010	0.990	0.000
S81.9 Open wound of lower leg, part unspecified	0.010	0.990	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.009	0.991	0.000
S82.2 Fracture of shaft of tibia	0.009	0.991	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.991	0.009
S89.9 Unspecified injury of lower leg	0.009	0.991	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.009	0.991	0.000
S90 Superficial injury of ankle and foot	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
S90-S99 Injuries to the ankle and foot	0.009	0.991	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.009	0.991	0.000
S82.7 Multiple fractures of lower leg	0.009	0.991	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.009	0.991	0.000
S82.9 Fracture of lower leg, part unspecified	0.009	0.991	0.000
S83.3 Tear of articular cartilage of knee, current	0.009	0.991	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.009	0.991	0.000
T66-T78 Other and unspecified effects of external causes	0.009	0.991	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.009	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
S83.1 Dislocation of knee	0.009	0.991	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.009	0.991	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.009	0.991	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.009	0.991	0.000
S50.7 Multiple superficial injuries of forearm	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
S20-S29 Injuries to the thorax	0.009	0.991	0.000
S89.7 Multiple injuries of lower leg	0.009	0.991	0.000
S89.1 Other specified injuries of lower leg	0.009	0.991	0.000
S89.0 Multiple injuries of lower leg	0.009	0.991	0.000
T36.0 Penicillins	0.009	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.009	0.991	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
T79.6 Traumatic ischaemia of muscle	0.009	0.991	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.008	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.991	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.009	0.991	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.008	0.991	0.000
T36.4 Tetracyclines	0.008	0.991	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.008	0.992	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
T36.9 Systemic antibiotic, unspecified	0.008	0.992	0.000
T36.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
T36.6 Rifamycins	0.008	0.992	0.000
T36.5 Aminoglycosides	0.008	0.992	0.000
T36.2 Chloramphenicol group	0.008	0.992	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.008	0.992	0.000
T44.0 Anticholinesterase agents	0.008	0.992	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.008	0.992	0.000
T36.3 Macrolides	0.008	0.992	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
S90.0 Contusion of ankle	0.008	0.992	0.000
T36.8 Other systemic antibiotics	0.008	0.992	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.008	0.992	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.008	0.992	0.000
S87.0 Crushing injury of knee	0.008	0.992	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.008	0.992	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.008	0.992	0.000
S90.8 Other superficial injuries of ankle and foot	0.008	0.992	0.000
S60-S69 Injuries to the wrist and hand	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.008	0.992	0.000
S70 Superficial injury of hip and thigh	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.992	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.008	0.992	0.000
S73.0 Dislocation of hip	0.008	0.992	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.008	0.992	0.000
S85.8 Injury of other blood vessels at lower leg level	0.008	0.992	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.008	0.992	0.000
S85.5 Injury of popliteal vein	0.008	0.992	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.008	0.992	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.008	0.992	0.000
S85.2 Injury of peroneal artery	0.008	0.992	0.000
S85.0 Injury of popliteal artery	0.008	0.992	0.000
S30.0 Contusion of lower back and pelvis	0.008	0.992	0.000
T39.4 Antirheumatics, not elsewhere classified	0.008	0.992	0.000
T39.2 Pyrazolone derivatives	0.008	0.992	0.000
T33-T35 Frostbite	0.008	0.992	0.000
S82.40 Fracture of fibula alone (closed)	0.008	0.992	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
S74 Injury of nerves at hip and thigh level	0.008	0.992	0.000
S82.0 Fracture of patella	0.008	0.992	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.008	0.992	0.000
S84.8 Injury of other nerves at lower leg level	0.008	0.992	0.000
S84.7 Injury of multiple nerves at lower leg level	0.008	0.992	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.008	0.992	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.008	0.992	0.000
S84.0 Injury of tibial nerve at lower leg level	0.008	0.992	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.008	0.992	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.008	0.992	0.000
S88.0 Traumatic amputation at knee level	0.008	0.992	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.008	0.992	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.008	0.992	0.000
S56 Injury of muscle and tendon at forearm level	0.008	0.992	0.000
S22.4 Multiple fractures of ribs	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.008	0.992	0.000
S79 Other and unspecified injuries of hip and thigh	0.008	0.992	0.000
S22.40 Multiple fractures of ribs (closed)	0.008	0.992	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.992	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.992	0.000
T37.5 Antiviral drugs	0.008	0.992	0.000
T37.4 Anthelminthics	0.008	0.992	0.000
T37.3 Other antiprotozoal drugs	0.008	0.992	0.000
T37.1 Antimycobacterial drugs	0.008	0.992	0.000
T37.0 Sulphonamides	0.008	0.992	0.000
S58 Traumatic amputation of forearm	0.008	0.992	0.000
S57 Crushing injury of forearm	0.008	0.992	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
S22.3 Fracture of rib	0.008	0.992	0.000
S82.41 Fracture of fibula alone (open)	0.008	0.992	0.000
S54 Injury of nerves at forearm level	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
T79.8 Other early complications of trauma	0.008	0.992	0.000
T41.5 Therapeutic gases	0.008	0.992	0.000
T41.4 Anaesthetic, unspecified	0.008	0.992	0.000
T41.3 Local anaesthetics	0.008	0.992	0.000
T41.1 Intravenous anaesthetics	0.008	0.992	0.000
T41.0 Inhaled anaesthetics	0.008	0.992	0.000
T79.7 Traumatic subcutaneous emphysema	0.008	0.992	0.000
S59 Other and unspecified injuries of forearm	0.008	0.992	0.000
S22.30 Fracture of rib (closed)	0.008	0.992	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.008	0.992	0.000
T71 Asphyxiation	0.008	0.992	0.000
T78.3 Angioneurotic oedema	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.992	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.007	0.992	0.000
S73.1 Sprain and strain of hip	0.007	0.992	0.000
T79.5 Traumatic anuria	0.007	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.992	0.000
T78 Adverse effects, not elsewhere classified	0.008	0.992	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.008	0.992	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.007	0.992	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
T48.4 Expectorants	0.007	0.993	0.000
T48.3 Antitussives	0.007	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
T48.0 Oxytocic drugs	0.007	0.993	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.007	0.993	0.000
S78 Traumatic amputation of hip and thigh	0.007	0.993	0.000
S77 Crushing injury of hip and thigh	0.007	0.993	0.000
S75 Injury of blood vessels at hip and thigh level	0.007	0.993	0.000
T49.9 Topical agent, unspecified	0.007	0.993	0.000
T49.8 Other topical agents	0.007	0.993	0.000
T49.7 Dental drugs, topically applied	0.007	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.007	0.993	0.000
T49.2 Local astringents and local detergents	0.007	0.993	0.000
T49.1 Antipruritics	0.007	0.993	0.000
S82.11 Fracture of upper end of tibia (open)	0.007	0.993	0.000
S72 Fracture of femur	0.007	0.993	0.000
T18.1 Foreign body in oesophagus	0.007	0.993	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.007	0.993	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.993	0.007
T40.5 Cocaine	0.007	0.993	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.007	0.993	0.000
S86.00 Unspecified injury of Achilles tendon	0.007	0.993	0.000
S30.1 Contusion of abdominal wall	0.007	0.993	0.000
T73 Effects of other deprivation	0.007	0.993	0.000
T79.9 Unspecified early complication of trauma	0.007	0.993	0.000
T79.1 Fat embolism (traumatic)	0.007	0.993	0.000
T79.0 Air embolism (traumatic)	0.007	0.993	0.000
K86.8 Other specified diseases of pancreas	0.007	0.993	0.000
S90.3 Contusion of other and unspecified parts of foot	0.007	0.993	0.000
T39.0 Salicylates	0.007	0.993	0.000
S71 Open wound of hip and thigh	0.007	0.993	0.000
S82.5 Fracture of medial malleolus	0.007	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.993	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.007	0.993	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.007	0.993	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.007	0.993	0.000
T68 Hypothermia	0.007	0.993	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.007	0.993	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.993	0.007
T40.1 Heroin	0.007	0.993	0.000
S98 Traumatic amputation of ankle and foot	0.007	0.993	0.000
S55 Injury of blood vessels at forearm level	0.007	0.993	0.000
S68 Traumatic amputation of wrist and hand	0.007	0.993	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.007	0.993	0.000
T18 Foreign body in alimentary tract	0.007	0.993	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.007	0.993	0.000
S31 Open wound of abdomen, lower back and pelvis	0.007	0.993	0.000
T00-T07 Injuries involving multiple body regions	0.007	0.993	0.000
S72.4 Fracture of lower end of femur	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.007	0.993	0.000
S90.2 Contusion of toe(s) with damage to nail	0.007	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
S72.40 Fracture of lower end of femur (closed)	0.007	0.993	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.007	0.993	0.000
S95 Injury of blood vessels at ankle and foot level	0.007	0.993	0.000
S94 Injury of nerves at ankle and foot level	0.007	0.993	0.000
S82.71 Multiple fractures of lower leg (open)	0.007	0.993	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.007	0.993	0.000
S60 Superficial injury of wrist and hand	0.007	0.993	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.007	0.993	0.000
S40-S49 Injuries to the shoulder and upper arm	0.007	0.993	0.000
S82.21 Fracture of shaft of tibia (open)	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
S65 Injury of blood vessels at wrist and hand level	0.007	0.993	0.000
T74 Maltreatment syndromes	0.007	0.993	0.000
T69 Other effects of reduced temperature	0.007	0.993	0.000
T67 Effects of heat and light	0.007	0.993	0.000
S26 Injury of heart	0.007	0.993	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.007	0.993	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.007	0.993	0.000
T70 Effects of air pressure and water pressure	0.007	0.993	0.000
T14 Injury of unspecified body region	0.007	0.993	0.000
S70.1 Contusion of thigh	0.007	0.993	0.000
S97 Crushing injury of ankle and foot	0.007	0.993	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.007	0.993	0.000
S60.0 Contusion of finger(s) without damage to nail	0.007	0.993	0.000
S24 Injury of nerves and spinal cord at thorax level	0.007	0.993	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.007	0.993	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.007	0.993	0.000
S25 Injury of blood vessels of thorax	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.993	0.000
S53.2 Traumatic rupture of radial collateral ligament	0.007	0.993	0.000
S29 Other and unspecified injuries of thorax	0.007	0.993	0.000
S92 Fracture of foot, except ankle	0.007	0.993	0.000
S37 Injury of urinary and pelvic organs	0.006	0.993	0.000
S70.0 Contusion of hip	0.006	0.993	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.006	0.993	0.000
S21 Open wound of thorax	0.006	0.993	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.993	0.007
S70.8 Other superficial injuries of hip and thigh	0.006	0.994	0.000
S62 Fracture at wrist and hand level	0.006	0.994	0.000
H01.0 Blepharitis	0.006	0.994	0.000
S53.4 Sprain and strain of elbow	0.006	0.994	0.000
T66 Unspecified effects of radiation	0.006	0.994	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.006	0.994	0.000
S72.8 Fractures of other parts of femur	0.006	0.994	0.000
S82.20 Fracture of shaft of tibia (closed)	0.006	0.994	0.000
S52 Fracture of forearm	0.006	0.994	0.000
T09 Other injuries of spine and trunk, level unspecified	0.006	0.994	0.000
S35.2 Injury of coeliac or mesenteric artery	0.006	0.994	0.000
S79.9 Unspecified injury of hip and thigh	0.006	0.994	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.006	0.994	0.000
S53.0 Dislocation of radial head	0.006	0.994	0.000
T11 Other injuries of upper limb, level unspecified	0.006	0.994	0.000
T08 Fracture of spine, level unspecified	0.006	0.994	0.000
S90.1 Contusion of toe(s) without damage to nail	0.006	0.994	0.000
T75 Effects of other external causes	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.006	0.994	0.000
S53.1 Dislocation of elbow, unspecified	0.006	0.994	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.006	0.994	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.006	0.994	0.000
T12 Fracture of lower limb, level unspecified	0.006	0.994	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.006	0.994	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.006	0.994	0.000
T10 Fracture of upper limb, level unspecified	0.006	0.994	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.006	0.994	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.006	0.994	0.000
S82.01 Fracture of patella (open)	0.006	0.994	0.000
S22.9 Fracture of bony thorax, part unspecified	0.006	0.994	0.000
S22.8 Fracture of other parts of bony thorax	0.006	0.994	0.000
T78.8 Other adverse effects, not elsewhere classified	0.006	0.994	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.006	0.994	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.006	0.994	0.000
S27 Injury of other and unspecified intrathoracic organs	0.006	0.994	0.000
S91 Open wound of ankle and foot	0.006	0.994	0.000
T26 Burn and corrosion confined to eye and adnexa	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
S62.3 Fracture of other metacarpal bone	0.006	0.994	0.000
S36 Injury of intra-abdominal organs	0.006	0.994	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.006	0.994	0.000
T28 Burn and corrosion of other internal organs	0.006	0.994	0.000
T27 Burn and corrosion of respiratory tract	0.006	0.994	0.000
S54.0 Injury of ulnar nerve at forearm level	0.006	0.994	0.000
T73.3 Exhaustion due to excessive exertion	0.006	0.994	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.006	0.994	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.006	0.994	0.000
T34 Frostbite with tissue necrosis	0.006	0.994	0.000
T33 Superficial frostbite	0.006	0.994	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.006	0.994	0.000
S74.8 Injury of other nerves at hip and thigh level	0.006	0.994	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.006	0.994	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.006	0.994	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.006	0.994	0.000
T78.2 Anaphylactic shock, unspecified	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
S22.5 Flail chest	0.006	0.994	0.000
S65.1 Injury of radial artery at wrist and hand level	0.006	0.994	0.000
S33.1 Dislocation of lumbar vertebra	0.006	0.994	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.006	0.994	0.000
S22.41 Multiple fractures of ribs (open)	0.006	0.994	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.006	0.994	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.006	0.994	0.000
S92.3 Fracture of metatarsal bone	0.006	0.994	0.000
S72.9 Fracture of femur, part unspecified	0.006	0.994	0.000
S79.7 Multiple injuries of hip and thigh	0.006	0.994	0.000
T79.4 Traumatic shock	0.006	0.994	0.000
S79.8 Other specified injuries of hip and thigh	0.006	0.994	0.000
S52.7 Multiple fractures of forearm	0.006	0.994	0.000
S57.9 Crushing injury of forearm, part unspecified	0.006	0.994	0.000
S57.8 Crushing injury of forearm, part unspecified	0.006	0.994	0.000
S57.7 Crushing injury of other parts of forearm	0.006	0.994	0.000
S57.0 Crushing injury of elbow	0.006	0.994	0.000
S58.9 Traumatic amputation of forearm, level unspecified	0.006	0.994	0.000
S58.1 Traumatic amputation at level between elbow and wrist	0.006	0.994	0.000
S58.0 Traumatic amputation at elbow level	0.006	0.994	0.000
S22.31 Fracture of rib (open)	0.006	0.994	0.000
S99 Other and unspecified injuries of ankle and foot	0.006	0.994	0.000
S54.2 Injury of radial nerve at forearm level	0.006	0.994	0.000
S54.9 Injury of unspecified nerve at forearm level	0.006	0.994	0.000
S54.8 Injury of other nerves at forearm level	0.006	0.994	0.000
S54.7 Injury of multiple nerves at forearm level	0.006	0.994	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.006	0.994	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.006	0.994	0.000
S82.70 Multiple fractures of lower leg (closed)	0.006	0.994	0.000
S31.1 Open wound of abdominal wall	0.006	0.994	0.000
S59.8 Other specified injuries of forearm	0.006	0.994	0.000
S59.7 Multiple injuries of forearm	0.006	0.994	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.994	0.006
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
S53.3 Traumatic rupture of ulnar collateral ligament	0.006	0.994	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.006	0.994	0.000
S71.0 Open wound of hip	0.006	0.994	0.000
T14.1 Open wound of unspecified body region	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
S52.70 Multiple fractures of forearm (closed)	0.006	0.994	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
T18.3 Foreign body in small intestine	0.006	0.994	0.000
T00 Superficial injuries involving multiple body regions	0.006	0.994	0.000
H18.8 Other specified disorders of cornea	0.000	0.994	0.006
S80 Superficial injury of lower leg	0.005	0.994	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.005	0.994	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.005	0.994	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.005	0.994	0.000
S35.5 Injury of iliac blood vessels	0.005	0.994	0.000
S35.4 Injury of renal blood vessels	0.005	0.994	0.000
S35.3 Injury of portal or splenic vein	0.005	0.994	0.000
S35.1 Injury of inferior vena cava	0.005	0.994	0.000
S35.0 Injury of abdominal aorta	0.005	0.994	0.000
S72.80 Fractures of other parts of femur (closed)	0.006	0.994	0.000
S59.9 Unspecified injury of forearm	0.005	0.994	0.000
S65.5 Injury of blood vessel(s) of other finger	0.006	0.994	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.994	0.000
T46.7 Peripheral vasodilators	0.005	0.994	0.000
S31.4 Open wound of vagina and vulva	0.006	0.994	0.000
T78.9 Adverse effect, unspecified	0.006	0.994	0.000
S32 Fracture of lumbar spine and pelvis	0.006	0.994	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.005	0.994	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.994	0.006
S23.4 Sprain and strain of ribs and sternum	0.005	0.994	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.005	0.994	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.005	0.994	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.005	0.994	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.005	0.994	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.005	0.994	0.000
S75.0 Injury of femoral artery	0.005	0.994	0.000
S77.2 Crushing injury of hip with thigh	0.005	0.994	0.000
S77.1 Crushing injury of thigh	0.005	0.994	0.000
S77.0 Crushing injury of hip	0.005	0.994	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.005	0.994	0.000
S78.1 Traumatic amputation at level between hip and knee	0.005	0.994	0.000
S78.0 Traumatic amputation at hip joint	0.005	0.994	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.994	0.006
K86.0 Alcohol-induced chronic pancreatitis	0.006	0.994	0.000
S54.1 Injury of median nerve at forearm level	0.005	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.994	0.000
S22.0 Fracture of thoracic vertebra	0.006	0.994	0.000
T14.9 Injury, unspecified	0.005	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.994	0.000
T32 Corrosions classified according to extent of body surface involved	0.005	0.994	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.005	0.994	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.005	0.994	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.005	0.994	0.000
S62.7 Multiple fractures of fingers	0.006	0.994	0.000
S92.30 Fracture of metatarsal bone (closed)	0.006	0.994	0.000
T18.0 Foreign body in mouth	0.005	0.994	0.000
T73.9 Effect of deprivation, unspecified	0.005	0.994	0.000
T73.8 Other effects of deprivation	0.005	0.994	0.000
T73.2 Exhaustion due to exposure	0.005	0.994	0.000
T73.1 Effects of thirst	0.005	0.994	0.000
T73.0 Effects of hunger	0.005	0.994	0.000
S34.1 Other injury of lumbar spinal cord	0.005	0.994	0.000
S67 Crushing injury of wrist and hand	0.005	0.994	0.000
S29.0 Injury of muscle and tendon at thorax level	0.005	0.994	0.000
S72.7 Multiple fractures of femur	0.005	0.994	0.000
H18 Other disorders of cornea	0.000	0.994	0.006
S93.6 Sprain and strain of other and unspecified parts of foot	0.005	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.994	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.005	0.995	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.005	0.995	0.000
S98.1 Traumatic amputation of one toe	0.005	0.995	0.000
S82.51 Fracture of medial malleolus (open)	0.005	0.995	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.005	0.995	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.005	0.995	0.000
S33.4 Traumatic rupture of symphysis pubis	0.005	0.995	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.005	0.995	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.005	0.995	0.000
S91.1 Open wound of toe(s) without damage to nail	0.005	0.995	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.005	0.995	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.005	0.995	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations