TreeWAS – Variant ID: rs4493682

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.742	0.258
T40.2 Other opioids	0.000	0.745	0.255
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.756	0.244
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.756	0.244
T39.1 4-Aminophenol derivatives	0.000	0.759	0.241
T40.4 Other synthetic narcotics	0.000	0.761	0.239
T40.6 Other and unspecified narcotics	0.000	0.772	0.228
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.780	0.220
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.790	0.210
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.793	0.207
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.799	0.201
T42.4 Benzodiazepines	0.000	0.802	0.198
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.815	0.185
T40.8 Lysergide [LSD]	0.000	0.815	0.185
T40.7 Cannabis (derivatives)	0.000	0.815	0.185
T40.5 Cocaine	0.000	0.815	0.185
T40.3 Methadone	0.000	0.815	0.185
T40.1 Heroin	0.000	0.815	0.185
T40.0 Opium	0.000	0.815	0.185
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.815	0.184
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.819	0.181
T36 Poisoning by systemic antibiotics	0.000	0.819	0.180
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.821	0.179
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.821	0.179
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.822	0.178
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.825	0.175
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.825	0.175
T39.4 Antirheumatics, not elsewhere classified	0.000	0.825	0.175
T39.2 Pyrazolone derivatives	0.000	0.825	0.175
T39.0 Salicylates	0.000	0.829	0.171
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.830	0.170
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.830	0.170
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.837	0.162
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.842	0.158
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.842	0.158
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.842	0.158
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.842	0.158
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.842	0.158
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.842	0.158
T44.0 Anticholinesterase agents	0.000	0.842	0.158
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.845	0.155
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.851	0.149
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.851	0.149
T42.3 Barbiturates	0.000	0.851	0.149
T42.2 Succinimides and oxazolidinediones	0.000	0.851	0.149
T46.1 Calcium-channel blockers	0.000	0.852	0.147
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.858	0.141
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.861	0.139
T42.1 Iminostilbenes	0.000	0.863	0.137
T42.0 Hydantoin derivatives	0.000	0.864	0.136
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.864	0.136
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.865	0.135
T36.0 Penicillins	0.000	0.865	0.135
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.866	0.134
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.867	0.132
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.867	0.132
T47.7 Emetics	0.000	0.867	0.132
T47.6 Antidiarrhoeal drugs	0.000	0.867	0.132
T47.5 Digestants	0.000	0.867	0.132
T47.4 Other laxatives	0.000	0.867	0.132
T47.3 Saline and osmotic laxatives	0.000	0.867	0.132
T47.2 Stimulant laxatives	0.000	0.867	0.132
T47.0 Histamine H(2)-receptor antagonists	0.000	0.867	0.132
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.868	0.132
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.868	0.131
T36.9 Systemic antibiotic, unspecified	0.000	0.870	0.129
T36.8 Other systemic antibiotics	0.000	0.870	0.129
T36.7 Antifungal antibiotics, systemically used	0.000	0.870	0.129
T36.6 Rifamycins	0.000	0.870	0.129
T36.5 Aminoglycosides	0.000	0.870	0.129
T36.4 Tetracyclines	0.000	0.870	0.129
T36.3 Macrolides	0.000	0.870	0.129
T36.2 Chloramphenicol group	0.000	0.870	0.129
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.870	0.129
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.871	0.129
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.871	0.129
T46.7 Peripheral vasodilators	0.000	0.871	0.129
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.871	0.129
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.871	0.129
T38.9 Other and unspecified hormone antagonists	0.000	0.872	0.128
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.872	0.128
T38.7 Androgens and anabolic congeners	0.000	0.872	0.128
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.872	0.128
T38.5 Other oestrogens and progestogens	0.000	0.872	0.128
T38.4 Oral contraceptives	0.000	0.872	0.128
T38.2 Antithyroid drugs	0.000	0.872	0.128
T38.0 Glucocorticoids and synthetic analogues	0.000	0.872	0.128
T45.5 Anticoagulants	0.000	0.872	0.128
T41.5 Therapeutic gases	0.000	0.874	0.126
T41.4 Anaesthetic, unspecified	0.000	0.874	0.126
T41.3 Local anaesthetics	0.000	0.874	0.126
T41.2 Other and unspecified general anaesthetics	0.000	0.874	0.126
T41.1 Intravenous anaesthetics	0.000	0.874	0.126
T41.0 Inhaled anaesthetics	0.000	0.874	0.126
T49.9 Topical agent, unspecified	0.000	0.874	0.126
T49.8 Other topical agents	0.000	0.874	0.126
T49.7 Dental drugs, topically applied	0.000	0.874	0.126
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.874	0.126
T49.5 Ophthalmological drugs and preparations	0.000	0.874	0.126
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.874	0.126
T49.3 Emollients, demulcents and protectants	0.000	0.874	0.126
T49.2 Local astringents and local detergents	0.000	0.874	0.126
T49.1 Antipruritics	0.000	0.874	0.126
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.874	0.126
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.876	0.124
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.878	0.122
T37.5 Antiviral drugs	0.000	0.878	0.122
T37.4 Anthelminthics	0.000	0.878	0.122
T37.3 Other antiprotozoal drugs	0.000	0.878	0.122
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.878	0.122
T37.1 Antimycobacterial drugs	0.000	0.878	0.122
T37.0 Sulphonamides	0.000	0.878	0.122
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.879	0.121
T38.1 Thyroid hormones and substitutes	0.000	0.881	0.119
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.883	0.117
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.883	0.117
T48.5 Anti-common-cold drugs	0.000	0.883	0.117
T48.4 Expectorants	0.000	0.883	0.117
T48.3 Antitussives	0.000	0.883	0.117
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.883	0.117
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.883	0.117
T48.0 Oxytocic drugs	0.000	0.883	0.117
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.884	0.116
T45.2 Vitamins, not elsewhere classified	0.000	0.887	0.113
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.889	0.111
T45.8 Other primarily systemic and haematological agents	0.000	0.889	0.111
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.889	0.111
T45.6 Fibrinolysis-affecting drugs	0.000	0.889	0.111
T45.4 Iron and its compounds	0.000	0.889	0.111
T45.3 Enzymes, not elsewhere classified	0.000	0.889	0.111
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.896	0.104
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.900	0.100
T43.9 Psychotropic drug, unspecified	0.000	0.905	0.095
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.905	0.095
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.905	0.095
T43.6 Psychostimulants with abuse potential	0.000	0.906	0.094
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.908	0.092
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.908	0.091
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.912	0.087
T45.0 Antiallergic and antiemetic drugs	0.000	0.919	0.080
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.922	0.077
T50.8 Diagnostic agents	0.000	0.937	0.063
T50.7 Analeptics and opioid receptor antagonists	0.000	0.937	0.063
T50.5 Appetite depressants	0.000	0.937	0.063
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.937	0.063
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.937	0.063
T50.1 Loop [high-ceiling] diuretics	0.000	0.937	0.063
T50.0 Mineralocorticoids and their antagonists	0.000	0.937	0.063
S82.60 Fracture of lateral malleolus (closed)	0.000	0.937	0.063
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.944	0.056
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.948	0.052
T50.4 Drugs affecting uric acid metabolism	0.001	0.949	0.050
S82.6 Fracture of lateral malleolus	0.000	0.956	0.044
T43.2 Other and unspecified antidepressants	0.000	0.967	0.033
S82.61 Fracture of lateral malleolus (open)	0.000	0.968	0.032
S82 Fracture of lower leg, including ankle	0.000	0.970	0.030
S82.40 Fracture of fibula alone (closed)	0.000	0.970	0.029
S82.4 Fracture of fibula alone	0.000	0.971	0.029
T50.9 Other and unspecified drugs, medicaments and biological substances	0.001	0.971	0.028
S82.0 Fracture of patella	0.000	0.974	0.026
S82.5 Fracture of medial malleolus	0.000	0.976	0.024
S82.00 Fracture of patella (closed)	0.000	0.976	0.024
S82.9 Fracture of lower leg, part unspecified	0.000	0.978	0.022
S82.41 Fracture of fibula alone (open)	0.000	0.979	0.021
S82.7 Multiple fractures of lower leg	0.000	0.979	0.020
S82.50 Fracture of medial malleolus (closed)	0.000	0.980	0.020
S82.01 Fracture of patella (open)	0.000	0.980	0.020
S82.2 Fracture of shaft of tibia	0.000	0.982	0.018
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.018	0.982	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.984	0.016
S82.51 Fracture of medial malleolus (open)	0.000	0.984	0.016
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.984	0.016
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.984	0.016
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.000	0.984	0.016
S82.71 Multiple fractures of lower leg (open)	0.000	0.985	0.015
S10-S19 Injuries to the neck	0.000	0.985	0.015
M89.9 Disorder of bone, unspecified	0.014	0.986	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.986	0.014
S82.1 Fracture of upper end of tibia	0.000	0.986	0.014
S82.3 Fracture of lower end of tibia	0.000	0.986	0.014
S90-S99 Injuries to the ankle and foot	0.000	0.986	0.014
S82.70 Multiple fractures of lower leg (closed)	0.000	0.986	0.013
M86.9 Osteomyelitis, unspecified	0.013	0.987	0.000
T79-T79 Certain early complications of trauma	0.000	0.987	0.013
S12 Fracture of neck	0.000	0.987	0.013
J39.2 Other diseases of pharynx	0.013	0.987	0.000
I73.0 Raynaud's syndrome	0.000	0.987	0.013
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.013	0.987	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.013	0.987	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.987	0.012
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.000	0.988	0.012
S81 Open wound of lower leg	0.000	0.988	0.012
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.988	0.012
S88 Traumatic amputation of lower leg	0.000	0.988	0.012
S87 Crushing injury of lower leg	0.000	0.988	0.012
S85 Injury of blood vessels at lower leg level	0.000	0.988	0.012
S84 Injury of nerves at lower leg level	0.000	0.988	0.012
M86 Osteomyelitis	0.012	0.988	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.988	0.012
T15-T19 Effects of foreign body entering through natural orifice	0.000	0.988	0.012
S90 Superficial injury of ankle and foot	0.000	0.988	0.012
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.000	0.988	0.012
S20-S29 Injuries to the thorax	0.000	0.988	0.012
S22.0 Fracture of thoracic vertebra	0.000	0.988	0.012
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.988	0.012
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.988	0.012
T33-T35 Frostbite	0.000	0.988	0.011
T26-T28 Burns and corrosions confined to eye and internal organs	0.000	0.988	0.011
S12.2 Fracture of other specified cervical vertebra	0.000	0.988	0.011
S12.7 Multiple fractures of cervical spine	0.000	0.989	0.011
M86.94 Osteomyelitis, unspecified (Hand)	0.011	0.989	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.989	0.011
S91 Open wound of ankle and foot	0.000	0.989	0.011
S22.4 Multiple fractures of ribs	0.000	0.989	0.011
M89 Other disorders of bone	0.011	0.989	0.000
S11 Open wound of neck	0.000	0.989	0.011
S82.20 Fracture of shaft of tibia (closed)	0.000	0.989	0.011
S70-S79 Injuries to the hip and thigh	0.000	0.989	0.011
S22.40 Multiple fractures of ribs (closed)	0.000	0.989	0.011
G62.9 Polyneuropathy, unspecified	0.011	0.989	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.989	0.011
T17 Foreign body in respiratory tract	0.000	0.989	0.011
T11 Other injuries of upper limb, level unspecified	0.000	0.989	0.011
S92 Fracture of foot, except ankle	0.000	0.989	0.011
M89.92 Disorder of bone, unspecified (Upper arm)	0.011	0.989	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.989	0.011
S14 Injury of nerves and spinal cord at neck level	0.000	0.989	0.011
S17 Crushing injury of neck	0.000	0.989	0.011
S15 Injury of blood vessels at neck level	0.000	0.989	0.011
S18 Traumatic amputation at neck level	0.000	0.989	0.011
S16 Injury of muscle and tendon at neck level	0.000	0.989	0.011
M89.99 Disorder of bone, unspecified (Site unspecified)	0.010	0.989	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.010	0.989	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.010	0.989	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.010	0.989	0.000
S82.86 Maisonneuve's fracture	0.000	0.989	0.010
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.989	0.011
T00-T07 Injuries involving multiple body regions	0.000	0.989	0.010
S90.8 Other superficial injuries of ankle and foot	0.000	0.989	0.010
S10 Superficial injury of neck	0.000	0.990	0.010
S86 Injury of muscle and tendon at lower leg level	0.000	0.990	0.010
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.990	0.010
M89.96 Disorder of bone, unspecified (Lower leg)	0.010	0.990	0.000
M86-M90 Other osteopathies	0.010	0.990	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.990	0.010
S98 Traumatic amputation of ankle and foot	0.000	0.990	0.010
S95 Injury of blood vessels at ankle and foot level	0.000	0.990	0.010
S94 Injury of nerves at ankle and foot level	0.000	0.990	0.010
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.990	0.010
S89 Other and unspecified injuries of lower leg	0.000	0.990	0.010
M86.93 Osteomyelitis, unspecified (Forearm)	0.010	0.990	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.010	0.990	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.010	0.990	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.010	0.990	0.000
M86.6 Other chronic osteomyelitis	0.010	0.990	0.000
S19 Other and unspecified injuries of neck	0.000	0.990	0.010
T11.0 Superficial injury of upper limb, level unspecified	0.000	0.990	0.010
M89.98 Disorder of bone, unspecified (Other)	0.010	0.990	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.990	0.010
S12.8 Fracture of other parts of neck	0.000	0.990	0.010
S12.0 Fracture of first cervical vertebra	0.000	0.990	0.010
S99 Other and unspecified injuries of ankle and foot	0.000	0.990	0.010
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.010	0.990	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.990	0.010
M89.94 Disorder of bone, unspecified (Hand)	0.010	0.990	0.000
S13.1 Dislocation of cervical vertebra	0.000	0.990	0.010
S81.7 Multiple open wounds of lower leg	0.000	0.990	0.010
S90.0 Contusion of ankle	0.000	0.990	0.010
T17.9 Foreign body in respiratory tract, part unspecified	0.000	0.990	0.010
S82.11 Fracture of upper end of tibia (open)	0.000	0.990	0.009
M86.98 Osteomyelitis, unspecified (Other)	0.009	0.991	0.000
T66-T78 Other and unspecified effects of external causes	0.000	0.991	0.009
S81.8 Open wound of other parts of lower leg	0.000	0.991	0.009
S50-S59 Injuries to the elbow and forearm	0.000	0.991	0.009
T63 Toxic effect of contact with venomous animals	0.000	0.991	0.009
T13 Other injuries of lower limb, level unspecified	0.000	0.991	0.009
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
S72 Fracture of femur	0.000	0.991	0.009
M86.8 Other osteomyelitis	0.009	0.991	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.991	0.009
T17.2 Foreign body in pharynx	0.000	0.991	0.009
S81.0 Open wound of knee	0.000	0.991	0.009
T31 Burns classified according to extent of body surface involved	0.000	0.991	0.009
S97 Crushing injury of ankle and foot	0.000	0.991	0.009
M89.5 Osteolysis	0.009	0.991	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.991	0.009
T51 Toxic effect of alcohol	0.000	0.991	0.009
T79.8 Other early complications of trauma	0.000	0.991	0.009
T12.X1 Fracture of lower limb, level unspecified (open)	0.000	0.991	0.009
T12.X0 Fracture of lower limb, level unspecified (closed)	0.000	0.991	0.009
T12 Fracture of lower limb, level unspecified	0.000	0.991	0.009
T10.X1 Fracture of upper limb, level unspecified (open)	0.000	0.991	0.009
T10.X0 Fracture of upper limb, level unspecified (closed)	0.000	0.991	0.009
T10 Fracture of upper limb, level unspecified	0.000	0.991	0.009
T08.X1 Fracture of spine, level unspecified (open)	0.000	0.991	0.009
T08.X0 Fracture of spine, level unspecified (closed)	0.000	0.991	0.009
T08 Fracture of spine, level unspecified	0.000	0.991	0.009
S90.3 Contusion of other and unspecified parts of foot	0.000	0.991	0.009
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.991	0.009
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.991	0.009
J39 Other diseases of upper respiratory tract	0.009	0.991	0.000
S92.0 Fracture of calcaneus	0.000	0.991	0.009
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.991	0.009
S84.8 Injury of other nerves at lower leg level	0.000	0.991	0.009
S84.7 Injury of multiple nerves at lower leg level	0.000	0.991	0.009
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.991	0.009
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.991	0.009
S84.0 Injury of tibial nerve at lower leg level	0.000	0.991	0.009
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.991	0.009
S85.8 Injury of other blood vessels at lower leg level	0.000	0.991	0.009
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.991	0.009
S85.5 Injury of popliteal vein	0.000	0.991	0.009
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.991	0.009
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.991	0.009
S85.2 Injury of peroneal artery	0.000	0.991	0.009
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.991	0.009
S85.0 Injury of popliteal artery	0.000	0.991	0.009
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.991	0.009
S87.0 Crushing injury of knee	0.000	0.991	0.009
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.991	0.009
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.991	0.009
S88.0 Traumatic amputation at knee level	0.000	0.991	0.009
M86.5 Other chronic haematogenous osteomyelitis	0.009	0.991	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.009	0.991	0.000
M86.3 Chronic multifocal osteomyelitis	0.009	0.991	0.000
M86.2 Subacute osteomyelitis	0.009	0.991	0.000
M86.1 Other acute osteomyelitis	0.009	0.991	0.000
M86.0 Acute haematogenous osteomyelitis	0.009	0.991	0.000
S13.5 Sprain and strain of thyroid region	0.000	0.991	0.009
S13.3 Multiple dislocations of neck	0.000	0.991	0.009
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.991	0.009
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.991	0.009
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.991	0.009
S90.2 Contusion of toe(s) with damage to nail	0.000	0.991	0.009
S90.1 Contusion of toe(s) without damage to nail	0.000	0.991	0.009
T19 Foreign body in genito-urinary tract	0.000	0.991	0.009
T15 Foreign body on external eye	0.000	0.991	0.009
T32 Corrosions classified according to extent of body surface involved	0.000	0.991	0.009
T30 Burn and corrosion, body region unspecified	0.000	0.991	0.009
T29 Burns and corrosions of multiple body regions	0.000	0.991	0.009
S92.5 Fracture of other toe	0.000	0.991	0.009
H26.8 Other specified cataract	0.009	0.991	0.000
S91.0 Open wound of ankle	0.000	0.991	0.009
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.000	0.991	0.009
S91.1 Open wound of toe(s) without damage to nail	0.000	0.991	0.009
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.991	0.009
S26 Injury of heart	0.000	0.991	0.009
S25 Injury of blood vessels of thorax	0.000	0.991	0.009
S24 Injury of nerves and spinal cord at thorax level	0.000	0.991	0.009
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.991	0.009
S22.01 Fracture of thoracic vertebra (open)	0.000	0.991	0.008
S22.9 Fracture of bony thorax, part unspecified	0.000	0.991	0.008
S22.8 Fracture of other parts of bony thorax	0.000	0.991	0.008
S72.4 Fracture of lower end of femur	0.000	0.991	0.009
S40-S49 Injuries to the shoulder and upper arm	0.000	0.991	0.009
T79.9 Unspecified early complication of trauma	0.000	0.991	0.008
T79.5 Traumatic anuria	0.000	0.991	0.008
T79.4 Traumatic shock	0.000	0.991	0.008
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.991	0.008
T79.1 Fat embolism (traumatic)	0.000	0.991	0.008
T79.0 Air embolism (traumatic)	0.000	0.991	0.008
S11.9 Open wound of neck, part unspecified	0.000	0.991	0.008
S13.4 Sprain and strain of cervical spine	0.000	0.991	0.008
T28 Burn and corrosion of other internal organs	0.000	0.991	0.008
T27 Burn and corrosion of respiratory tract	0.000	0.991	0.008
T26 Burn and corrosion confined to eye and adnexa	0.000	0.991	0.008
T35 Frostbite involving multiple body regions and unspecified frostbite	0.000	0.991	0.008
T34 Frostbite with tissue necrosis	0.000	0.991	0.008
T33 Superficial frostbite	0.000	0.991	0.008
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.991	0.008
S92.1 Fracture of talus	0.000	0.991	0.008
T14 Injury of unspecified body region	0.000	0.991	0.008
M87 Osteonecrosis	0.008	0.991	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.991	0.008
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.991	0.008
T58 Toxic effect of carbon monoxide	0.000	0.991	0.008
J39.8 Other specified diseases of upper respiratory tract	0.008	0.992	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.992	0.008
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.992	0.008
S12.1 Fracture of second cervical vertebra	0.000	0.992	0.008
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.992	0.008
S43.0 Dislocation of shoulder joint	0.000	0.992	0.008
S92.7 Multiple fractures of foot	0.000	0.992	0.008
S91.3 Open wound of other parts of foot	0.000	0.992	0.008
S89.8 Other specified injuries of lower leg	0.000	0.992	0.008
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.992	0.008
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.992	0.008
T56 Toxic effect of metals	0.000	0.992	0.008
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.992	0.008
T60 Toxic effect of pesticides	0.000	0.992	0.008
T57 Toxic effect of other inorganic substances	0.000	0.992	0.008
T54 Toxic effect of corrosive substances	0.000	0.992	0.008
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.992	0.008
T52 Toxic effect of organic solvents	0.000	0.992	0.008
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.992	0.008
T55 Toxic effect of soaps and detergents	0.000	0.992	0.008
M86.66 Other chronic osteomyelitis (Lower leg)	0.008	0.992	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.992	0.008
S91.2 Open wound of toe(s) with damage to nail	0.000	0.992	0.008
S72.40 Fracture of lower end of femur (closed)	0.000	0.992	0.008
S22.5 Flail chest	0.000	0.992	0.008
S22.41 Multiple fractures of ribs (open)	0.000	0.992	0.008
M89.6 Osteopathy after poliomyelitis	0.008	0.992	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.008	0.992	0.000
M89.2 Other disorders of bone development and growth	0.008	0.992	0.000
M89.1 Epiphyseal arrest	0.008	0.992	0.000
M89.0 Algoneurodystrophy	0.008	0.992	0.000
S11.8 Open wound of other parts of neck	0.000	0.992	0.008
S11.7 Multiple open wounds of neck	0.000	0.992	0.008
S11.2 Open wound involving pharynx and cervical oesophagus	0.000	0.992	0.008
S11.1 Open wound involving thyroid gland	0.000	0.992	0.008
S11.0 Open wound involving larynx and trachea	0.000	0.992	0.008
S71 Open wound of hip and thigh	0.000	0.992	0.008
T01 Open wounds involving multiple body regions	0.000	0.992	0.008
T51.0 Ethanol	0.000	0.992	0.008
S78 Traumatic amputation of hip and thigh	0.000	0.992	0.008
S77 Crushing injury of hip and thigh	0.000	0.992	0.008
S75 Injury of blood vessels at hip and thigh level	0.000	0.992	0.008
S74 Injury of nerves at hip and thigh level	0.000	0.992	0.008
S10.9 Superficial injury of neck, part unspecified	0.000	0.992	0.008
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.992	0.008
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.992	0.008
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.992	0.008
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.992	0.008
T17.4 Foreign body in trachea	0.000	0.992	0.008
T17.3 Foreign body in larynx	0.000	0.992	0.008
T17.1 Foreign body in nostril	0.000	0.992	0.008
T17.0 Foreign body in nasal sinus	0.000	0.992	0.008
S92.9 Fracture of foot, unspecified	0.000	0.992	0.008
T11.9 Unspecified injury of upper limb, level unspecified	0.000	0.992	0.008
T11.8 Other specified injuries of upper limb, level unspecified	0.000	0.992	0.008
T11.6 Traumatic amputation of upper limb, level unspecified	0.000	0.992	0.008
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.000	0.992	0.008
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.000	0.992	0.008
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.000	0.992	0.008
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.000	0.992	0.008
T11.1 Open wound of upper limb, level unspecified	0.000	0.992	0.008
S19.8 Other specified injuries of neck	0.000	0.992	0.008
T63.4 Venom of other arthropods	0.000	0.992	0.008
S12.91 Fracture of neck, part unspecified (open)	0.000	0.992	0.008
S92.4 Fracture of great toe	0.000	0.992	0.008
S54 Injury of nerves at forearm level	0.000	0.992	0.008
S14.6 Injury of other and unspecified nerves of neck	0.000	0.992	0.008
S14.5 Injury of cervical sympathetic nerves	0.000	0.992	0.008
S14.4 Injury of peripheral nerves of neck	0.000	0.992	0.008
S14.2 Injury of nerve root of cervical spine	0.000	0.992	0.008
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.992	0.008
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.992	0.008
S15.9 Injury of unspecified blood vessel at neck level	0.000	0.992	0.008
S15.8 Injury of other blood vessels at neck level	0.000	0.992	0.008
S15.7 Injury of multiple blood vessels at neck level	0.000	0.992	0.008
S15.3 Injury of internal jugular vein	0.000	0.992	0.008
S15.2 Injury of external jugular vein	0.000	0.992	0.008
S15.1 Injury of vertebral artery	0.000	0.992	0.008
S15.0 Injury of carotid artery	0.000	0.992	0.008
S17.9 Crushing injury of neck, part unspecified	0.000	0.992	0.008
S17.8 Crushing injury of other parts of neck	0.000	0.992	0.008
S17.0 Crushing injury of larynx and traches	0.000	0.992	0.008
S27 Injury of other and unspecified intrathoracic organs	0.000	0.992	0.008
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.992	0.008
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.992	0.008
T06 Other injuries involving multiple body regions, not elsewhere classified	0.000	0.992	0.008
T05 Traumatic amputations involving multiple body regions	0.000	0.992	0.008
T04 Crushing injuries involving multiple body regions	0.000	0.992	0.008
T03 Dislocations, sprains and strains involving multiple body regions	0.000	0.992	0.008
T07 Unspecified multiple injuries	0.000	0.992	0.008
T09 Other injuries of spine and trunk, level unspecified	0.000	0.992	0.008
M89.55 Osteolysis (Pelvic region and thigh)	0.008	0.992	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.992	0.008
S86.0 Injury of Achilles tendon	0.000	0.992	0.008
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.992	0.008
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.992	0.008
S10.7 Multiple superficial injuries of neck	0.000	0.992	0.008
S10.1 Other and unspecified superficial injuries of throat	0.000	0.992	0.008
S10.0 Contusion of throat	0.000	0.992	0.008
M89.3 Hypertrophy of bone	0.007	0.992	0.000
M87.2 Osteonecrosis due to previous trauma	0.008	0.992	0.000
S72.1 Pertrochanteric fracture	0.000	0.992	0.008
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.992	0.007
T62 Toxic effect of other noxious substances eaten as food	0.000	0.992	0.007
T65 Toxic effect of other and unspecified substances	0.000	0.992	0.007
T16 Foreign body in ear	0.000	0.992	0.007
S51 Open wound of forearm	0.000	0.992	0.008
S92.00 Fracture of calcaneus (closed)	0.000	0.992	0.008
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.992	0.007
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.992	0.007
S94.8 Injury of other nerves at ankle and foot level	0.000	0.992	0.007
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.992	0.007
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.992	0.007
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.992	0.007
S94.1 Injury of medial plantar nerve	0.000	0.992	0.007
S94.0 Injury of lateral plantar nerve	0.000	0.992	0.007
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.992	0.007
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.992	0.007
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.992	0.007
S95.2 Injury of dorsal vein of foot	0.000	0.992	0.007
S95.1 Injury of plantar artery of foot	0.000	0.992	0.007
S95.0 Injury of dorsal artery of foot	0.000	0.992	0.007
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.992	0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations