TreeWAS – Variant ID: rs4524

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	0.000	0.000	1.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.000	1.000
I80 Phlebitis and thrombophlebitis	0.000	0.001	0.999
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.003	0.997
D68 Other coagulation defects	0.000	0.034	0.966
D68.5 Primary Thrombophilia	0.000	0.047	0.953
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.061	0.939
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.180	0.820
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.185	0.815
D68.8 Other specified coagulation defects	0.000	0.210	0.790
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.220	0.780
D68.1 Hereditary factor XI deficiency	0.000	0.261	0.739
D68.4 Acquired coagulation factor deficiency	0.000	0.307	0.693
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.387	0.613
D68.9 Coagulation defect, unspecified	0.000	0.409	0.591
D68.6 Other Thrombophilia	0.000	0.415	0.585
Z86.7 Personal history of diseases of the circulatory system	0.000	0.421	0.579
D68.0 Von Willebrand's disease	0.000	0.427	0.573
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.589	0.411
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.643	0.357
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.712	0.288
D66 Hereditary factor VIII deficiency	0.000	0.737	0.263
D67 Hereditary factor IX deficiency	0.000	0.758	0.242
I26 Pulmonary embolism	0.000	0.813	0.187
D69 Purpura and other haemorrhagic conditions	0.000	0.827	0.173
D69.2 Other nonthrombocytopenic purpura	0.000	0.861	0.139
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.862	0.138
D69.5 Secondary thrombocytopenia	0.000	0.864	0.136
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.872	0.128
D69.8 Other specified haemorrhagic conditions	0.000	0.876	0.124
D69.1 Qualitative platelet defects	0.000	0.876	0.124
D69.4 Other primary thrombocytopenia	0.000	0.876	0.124
D69.9 Haemorrhagic condition, unspecified	0.000	0.893	0.106
D69.0 Allergic purpura	0.000	0.906	0.094
J31.0 Chronic rhinitis	0.000	0.922	0.078
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.942	0.058
J31.2 Chronic pharyngitis	0.000	0.948	0.052
J31.1 Chronic nasopharyngitis	0.000	0.953	0.047
K74.3 Primary biliary cirrhosis	0.044	0.956	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.958	0.042
K74 Fibrosis and cirrhosis of liver	0.035	0.965	0.000
K74.0 Hepatic fibrosis	0.035	0.965	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.969	0.031
K74.5 Biliary cirrhosis, unspecified	0.029	0.971	0.000
D55-D59 Haemolytic anaemias	0.000	0.971	0.029
K74.1 Hepatic sclerosis	0.027	0.973	0.000
I28 Other diseases of pulmonary vessels	0.000	0.973	0.027
D58 Other hereditary haemolytic anaemias	0.000	0.974	0.026
K74.4 Secondary biliary cirrhosis	0.025	0.974	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.025	0.974	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.976	0.024
D58.0 Hereditary spherocytosis	0.000	0.977	0.023
D59 Acquired haemolytic anaemia	0.000	0.978	0.022
D56 Thalassaemia	0.000	0.978	0.022
D57 Sickle-cell disorders	0.000	0.979	0.021
D55 Anaemia due to enzyme disorders	0.000	0.979	0.021
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.980	0.020
I28.1 Aneurysm of pulmonary artery	0.000	0.980	0.020
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.980	0.020
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.980	0.020
D50-D53 Nutritional anaemias	0.000	0.981	0.019
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.981	0.019
D58.1 Hereditary elliptocytosis	0.000	0.981	0.019
I27 Other pulmonary heart diseases	0.000	0.982	0.018
D56.1 Beta thalassaemia	0.000	0.983	0.017
I28.8 Other specified diseases of pulmonary vessels	0.000	0.983	0.017
M84.03 Malunion of fracture (Forearm)	0.017	0.983	0.000
D52 Folate deficiency anaemia	0.000	0.983	0.017
M84.0 Malunion of fracture	0.017	0.983	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.983	0.016
M84 Disorders of continuity of bone	0.016	0.984	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.984	0.016
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.984	0.016
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.984	0.016
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.984	0.016
D59.3 Haemolytic-uraemic syndrome	0.000	0.984	0.016
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.984	0.016
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.984	0.016
M80 Osteoporosis with pathological fracture	0.016	0.984	0.000
D56.9 Thalassaemia, unspecified	0.000	0.984	0.016
D56.8 Other thalassaemias	0.000	0.984	0.016
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.984	0.016
D56.2 Delta-beta thalassaemia	0.000	0.984	0.016
D56.0 Alpha thalassaemia	0.000	0.984	0.016
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.016	0.984	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.015	0.985	0.000
D56.3 Thalassaemia trait	0.000	0.985	0.015
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.985	0.015
D55.8 Other anaemias due to enzyme disorders	0.000	0.985	0.015
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.985	0.015
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.985	0.015
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.985	0.015
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.985	0.015
D57.8 Other sickle-cell disorders	0.000	0.985	0.015
D57.3 Sickle-cell trait	0.000	0.985	0.015
D57.2 Double heterozygous sickling disorders	0.000	0.985	0.015
D57.1 Sickle-cell anaemia without crisis	0.000	0.985	0.015
D57.0 Sickle-cell anaemia with crisis	0.000	0.985	0.015
M80-M85 Disorders of bone density and structure	0.015	0.985	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.985	0.015
D80-D89 Certain disorders involving the immune mechanism	0.000	0.985	0.015
D58.2 Other haemoglobinopathies	0.000	0.985	0.015
D53 Other nutritional anaemias	0.000	0.985	0.015
I27.9 Pulmonary heart disease, unspecified	0.000	0.985	0.015
M85 Other disorders of bone density and structure	0.014	0.986	0.000
M84.4 Pathological fracture, not elsewhere classified	0.014	0.986	0.000
M84.8 Other disorders of continuity of bone	0.014	0.986	0.000
M84.02 Malunion of fracture (Upper arm)	0.014	0.986	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.014	0.986	0.000
K76.9 Liver disease, unspecified	0.014	0.986	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.986	0.013
M80.8 Other osteoporosis with pathological fracture	0.013	0.987	0.000
M85.6 Other cyst of bone	0.013	0.987	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.987	0.013
M84.48 Pathological fracture, not elsewhere classified (Other)	0.013	0.987	0.000
M84.06 Malunion of fracture (Lower leg)	0.013	0.987	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.013	0.987	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.013	0.987	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.012	0.987	0.000
D52.8 Other folate deficiency anaemias	0.000	0.988	0.012
D52.1 Drug-induced folate deficiency anaemia	0.000	0.988	0.012
D52.0 Dietary folate deficiency anaemia	0.000	0.988	0.012
M84.01 Malunion of fracture (Shoulder region)	0.012	0.988	0.000
M84.09 Malunion of fracture (Site unspecified)	0.012	0.988	0.000
M84.08 Malunion of fracture (Other)	0.012	0.988	0.000
M84.00 Malunion of fracture (Multiple sites)	0.012	0.988	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.988	0.012
M85.65 Other cyst of bone (Pelvic region and thigh)	0.012	0.988	0.000
D83 Common variable immunodeficiency	0.000	0.988	0.012
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.012	0.988	0.000
M84.9 Disorder of continuity of bone, unspecified	0.012	0.988	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.988	0.012
M84.2 Delayed union of fracture	0.012	0.988	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.012	0.988	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.012	0.988	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.012	0.988	0.000
G70.0 Myasthenia gravis	0.012	0.988	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.988	0.012
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.011	0.988	0.000
M84.3 Stress fracture, not elsewhere classified	0.011	0.988	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.012	0.988	0.000
M85.4 Solitary bone cyst	0.011	0.988	0.000
M83 Adult osteomalacia	0.011	0.989	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.011	0.989	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.011	0.989	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.011	0.989	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.011	0.989	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.011	0.989	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.011	0.989	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.011	0.989	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.989	0.011
M85.0 Fibrous dysplasia (monostotic)	0.011	0.989	0.000
D81 Combined immunodeficiencies	0.000	0.989	0.011
M84.04 Malunion of fracture (Hand)	0.011	0.989	0.000
D53.8 Other specified nutritional anaemias	0.000	0.989	0.011
D53.2 Scorbutic anaemia	0.000	0.989	0.011
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.989	0.011
D53.0 Protein deficiency anaemia	0.000	0.989	0.011
M84.07 Malunion of fracture (Ankle and foot)	0.011	0.989	0.000
M85.66 Other cyst of bone (Lower leg)	0.011	0.989	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
O70.1 Second degree perineal laceration during delivery	0.011	0.989	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.011	0.989	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.010	0.989	0.000
M85.5 Aneurysmal bone cyst	0.010	0.989	0.000
M85.3 Osteitis condensans	0.010	0.989	0.000
M85.2 Hyperostosis of skull	0.010	0.989	0.000
M85.1 Skeletal fluorosis	0.010	0.989	0.000
M85.8 Other specified disorders of bone density and structure	0.010	0.989	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.010	0.990	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.010	0.990	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.010	0.990	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.010	0.990	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.010	0.990	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.010	0.990	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.010	0.990	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.010	0.990	0.000
M84.88 Other disorders of continuity of bone (Other)	0.010	0.990	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.010	0.990	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.010	0.990	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.010	0.990	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.010	0.990	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.010	0.990	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.010	0.990	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.010	0.990	0.000
M85.68 Other cyst of bone (Other)	0.010	0.990	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.990	0.010
D83.9 Common variable immunodeficiency, unspecified	0.000	0.990	0.010
D84 Other immunodeficiencies	0.000	0.990	0.010
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.990	0.010
M80.88 Other osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
U80.1 Methicillin resistant agent	0.000	0.990	0.010
M85.9 Disorder of bone density and structure, unspecified	0.010	0.990	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.990	0.010
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.990	0.010
D51.2 Transcobalamin II deficiency	0.000	0.990	0.010
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.990	0.010
M82 Osteoporosis in diseases classified elsewhere	0.010	0.990	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.010	0.990	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M85.69 Other cyst of bone (Site unspecified)	0.010	0.990	0.000
M85.63 Other cyst of bone (Forearm)	0.010	0.990	0.000
M85.62 Other cyst of bone (Upper arm)	0.010	0.990	0.000
M85.61 Other cyst of bone (Shoulder region)	0.010	0.990	0.000
M85.60 Other cyst of bone (Multiple sites)	0.010	0.990	0.000
M85.64 Other cyst of bone (Hand)	0.010	0.990	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.010	0.990	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.009	0.990	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.990	0.009
U80 Agent resistant to penicillin and related antibiotics	0.000	0.990	0.010
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.009	0.990	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.009	0.990	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.009	0.990	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.009	0.990	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.990	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.009	0.990	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.009	0.990	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.009	0.990	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.009	0.990	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.991	0.009
D86 Sarcoidosis	0.000	0.991	0.009
M81 Osteoporosis without pathological fracture	0.009	0.991	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.009	0.991	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.009	0.991	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.991	0.009
D83.8 Other common variable immunodeficiencies	0.000	0.991	0.009
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.991	0.009
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.991	0.009
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.991	0.009
M85.67 Other cyst of bone (Ankle and foot)	0.009	0.991	0.000
K70-K77 Diseases of liver	0.009	0.991	0.000
U81.0 Vancomycin resistant agent	0.000	0.991	0.009
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.009	0.991	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.009	0.991	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.009	0.991	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.009	0.991	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.009	0.991	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.009	0.991	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.009	0.991	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.009	0.991	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.009	0.991	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.991	0.009
M83.8 Other adult osteomalacia	0.009	0.991	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.009	0.991	0.000
Y42.7 Androgens and anabolic congeners	0.009	0.991	0.000
K76 Other diseases of liver	0.009	0.991	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.991	0.009
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.008	0.991	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.008	0.991	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.008	0.991	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.008	0.991	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.008	0.991	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.008	0.991	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.008	0.991	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.008	0.991	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.008	0.991	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.008	0.991	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.008	0.991	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.008	0.991	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.008	0.991	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.008	0.991	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.991	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.008	0.991	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.008	0.991	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.008	0.991	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.008	0.991	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.008	0.991	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.008	0.991	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.008	0.991	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.008	0.991	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.008	0.991	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.991	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.008	0.991	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.008	0.991	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.008	0.991	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.008	0.991	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.008	0.991	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.008	0.991	0.000
M84.28 Delayed union of fracture (Other)	0.008	0.991	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.008	0.991	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.008	0.991	0.000
M84.24 Delayed union of fracture (Hand)	0.008	0.991	0.000
M84.23 Delayed union of fracture (Forearm)	0.008	0.991	0.000
M84.22 Delayed union of fracture (Upper arm)	0.008	0.991	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.008	0.991	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.008	0.991	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.009	0.991	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.008	0.991	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.008	0.991	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.008	0.991	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.008	0.991	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.008	0.991	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.008	0.991	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.008	0.991	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.008	0.991	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.008	0.991	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.008	0.991	0.000
M85.48 Solitary bone cyst (Other)	0.008	0.991	0.000
M85.46 Solitary bone cyst (Lower leg)	0.008	0.991	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.008	0.991	0.000
M85.44 Solitary bone cyst (Hand)	0.008	0.991	0.000
M85.43 Solitary bone cyst (Forearm)	0.008	0.991	0.000
M85.42 Solitary bone cyst (Upper arm)	0.008	0.991	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.008	0.991	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.008	0.991	0.000
M83.9 Adult osteomalacia, unspecified	0.008	0.992	0.000
M83.5 Other drug-induced osteomalacia in adults	0.008	0.992	0.000
M83.4 Aluminum bone disease	0.008	0.992	0.000
M83.3 Adult osteomalacia due to malnutrition	0.008	0.992	0.000
M83.2 Adult osteomalacia due to malabsorption	0.008	0.992	0.000
M83.0 Puerperal osteomalacia	0.008	0.992	0.000
M84.26 Delayed union of fracture (Lower leg)	0.008	0.992	0.000
U80.0 Penicillin resistant agent	0.000	0.992	0.008
M83.1 Senile osteomalacia	0.008	0.992	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.008	0.992	0.000
D82.1 Di George's syndrome	0.000	0.992	0.008
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.992	0.008
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.992	0.008
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.992	0.008
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.992	0.008
D82.2 Immunodeficiency with short-limbed stature	0.000	0.992	0.008
D82.0 Wiskott-Aldrich syndrome	0.000	0.992	0.008
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.008	0.992	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.008	0.992	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.008	0.992	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.008	0.992	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.008	0.992	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.008	0.992	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.008	0.992	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.008	0.992	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.008	0.992	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.992	0.008
D81.8 Other combined immunodeficiencies	0.000	0.992	0.008
D81.7 Major histocompatibility complex class II deficiency	0.000	0.992	0.008
D81.6 Major histocompatibility complex class I deficiency	0.000	0.992	0.008
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.992	0.008
D81.4 Nezelof's syndrome	0.000	0.992	0.008
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.992	0.008
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.992	0.008
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.992	0.008
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.992	0.008
D86.9 Sarcoidosis, unspecified	0.000	0.992	0.008
G70 Myasthenia gravis and other myoneural disorders	0.008	0.992	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.008	0.992	0.000
M85.18 Skeletal fluorosis (Other)	0.008	0.992	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.008	0.992	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.008	0.992	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.008	0.992	0.000
M85.14 Skeletal fluorosis (Hand)	0.008	0.992	0.000
M85.13 Skeletal fluorosis (Forearm)	0.008	0.992	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.008	0.992	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.008	0.992	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.008	0.992	0.000
M85.29 Hyperostosis of skull-Site unspec	0.008	0.992	0.000
M85.28 Hyperostosis of skull-Other	0.008	0.992	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.008	0.992	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.008	0.992	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.008	0.992	0.000
M85.24 Hyperostosis of skull-Hand	0.008	0.992	0.000
M85.23 Hyperostosis of skull-Forearm	0.008	0.992	0.000
M85.22 Hyperostosis of skull-Upper arm	0.008	0.992	0.000
M85.21 Hyperostosis of skull-Shldr region	0.008	0.992	0.000
M85.20 Hyperostosis of skull-Mult sites	0.008	0.992	0.000
M85.39 Osteitis condensans (Site unspecified)	0.008	0.992	0.000
M85.38 Osteitis condensans (Other)	0.008	0.992	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.008	0.992	0.000
M85.36 Osteitis condensans (Lower leg)	0.008	0.992	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.008	0.992	0.000
M85.34 Osteitis condensans (Hand)	0.008	0.992	0.000
M85.33 Osteitis condensans (Forearm)	0.008	0.992	0.000
M85.32 Osteitis condensans (Upper arm)	0.008	0.992	0.000
M85.31 Osteitis condensans (Shoulder region)	0.008	0.992	0.000
M85.30 Osteitis condensans (Multiple sites)	0.008	0.992	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.008	0.992	0.000
M85.58 Aneurysmal bone cyst (Other)	0.008	0.992	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.008	0.992	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.008	0.992	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.008	0.992	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.008	0.992	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.008	0.992	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.008	0.992	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.008	0.992	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.008	0.992	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.992	0.008
M85.84 Other specified disorders of bone density and structure (Hand)	0.008	0.992	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.008	0.992	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.008	0.992	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.008	0.992	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.992	0.008
C21.0 Anus, unspecified	0.008	0.992	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.007	0.992	0.000
D84.1 Defects in the complement system	0.000	0.992	0.007
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.992	0.007
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.007	0.992	0.000
D86.3 Sarcoidosis of skin	0.000	0.992	0.007
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.007	0.992	0.000
U51 Admission status on psychiatric patients	0.000	0.992	0.007
M85.98 Disorder of bone density and structure, unspecified (Other)	0.007	0.993	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.007	0.993	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.007	0.993	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.007	0.993	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.007	0.993	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.007	0.993	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.007	0.993	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.007	0.993	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.007	0.993	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.007	0.993	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.007	0.993	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.993	0.007
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.007	0.993	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.007	0.993	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.007	0.993	0.000
K71 Toxic liver disease	0.007	0.993	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.993	0.007
M81.4 Drug-induced osteoporosis	0.007	0.993	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.007	0.993	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.007	0.993	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.993	0.007
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.993	0.007
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.993	0.007
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.993	0.007
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.993	0.007
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.993	0.007
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.993	0.007
K74.6 Other and unspecified cirrhosis of liver	0.007	0.993	0.000
K73 Chronic hepatitis, not elsewhere classified	0.007	0.993	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.007	0.993	0.000
M81.8 Other osteoporosis	0.007	0.993	0.000
M81.6 Localised osteoporosis [Lequesne]	0.007	0.993	0.000
M81.5 Idiopathic osteoporosis	0.007	0.993	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.007	0.993	0.000
M81.1 Postoophorectomy osteoporosis	0.007	0.993	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.007	0.993	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.993	0.007
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.007	0.993	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.993	0.007
D60-D64 Aplastic and other anaemias	0.000	0.993	0.007
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.007	0.993	0.000
G70.8 Other specified myoneural disorders	0.007	0.993	0.000
M81.2 Osteoporosis of disuse	0.007	0.993	0.000
M81.0 Postmenopausal osteoporosis	0.007	0.993	0.000
K77 Liver disorders in diseases classified elsewhere	0.007	0.993	0.000
U50 Level of care administered to neonates	0.000	0.993	0.006
U07 Emergency use of U07	0.000	0.993	0.006
U06 Emergency use of U06	0.000	0.993	0.006
U04 Severe acute respiratory syndrome [SARS]	0.000	0.993	0.006
U52 First in a series of a regular day/night admissions	0.000	0.993	0.006
M83.89 Other adult osteomalacia (Site unspecified)	0.006	0.993	0.000
M83.88 Other adult osteomalacia (Other)	0.006	0.993	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.006	0.993	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.006	0.993	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.006	0.993	0.000
M83.84 Other adult osteomalacia (Hand)	0.006	0.993	0.000
M83.83 Other adult osteomalacia (Forearm)	0.006	0.993	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.006	0.993	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.006	0.993	0.000
K76.5 Hepatic veno-occlusive disease	0.006	0.993	0.000
K76.4 Peliosis hepatis	0.006	0.993	0.000
K76.3 Infarction of liver	0.006	0.993	0.000
K76.2 Central haemorrhagic necrosis of liver	0.006	0.993	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.993	0.006
D84.8 Other specified immunodeficiencies	0.000	0.994	0.006
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.994	0.006
K76.8 Other specified diseases of liver	0.006	0.994	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.006	0.994	0.000
M83.08 Puerperal osteomalacia (Other)	0.006	0.994	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.006	0.994	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.006	0.994	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.006	0.994	0.000
M83.04 Puerperal osteomalacia (Hand)	0.006	0.994	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.006	0.994	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations