TreeWAS – Variant ID: rs4530754

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M50.3 Other cervical disk degeneration	0.318	0.682	0.000
M50 Cervical disk disorders	0.284	0.716	0.000
M50.1 Cervical disk disorder with radiculopathy	0.267	0.733	0.000
M50.0 Cervical disk disorder with myelopathy	0.266	0.734	0.000
M50.8 Other cervical disk disorders	0.203	0.797	0.000
M50.2 Other cervical disk displacement	0.183	0.817	0.000
M50.9 Cervical disk disorder, unspecified	0.165	0.835	0.000
R60.0 Localised oedema	0.000	0.938	0.062
R60 Oedema, not elsewhere classified	0.000	0.950	0.050
R60.1 Generalised oedema	0.000	0.951	0.049
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.042	0.958	0.000
J44 Other chronic obstructive pulmonary disease	0.034	0.966	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.034	0.966	0.000
R60.9 Oedema, unspecified	0.000	0.967	0.033
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.031	0.969	0.000
M50-M54 Other dorsopathies	0.029	0.971	0.000
M79.66 Pain in limb (Lower leg)	0.027	0.973	0.000
M79.64 Pain in limb (Hand)	0.026	0.974	0.000
M79.6 Pain in limb	0.025	0.975	0.000
M79.69 Pain in limb (Site unspecified)	0.024	0.976	0.000
M53 Other dorsopathies, not elsewhere classified	0.022	0.978	0.000
M79.68 Pain in limb (Other)	0.020	0.980	0.000
M79.67 Pain in limb (Ankle and foot)	0.019	0.981	0.000
M79.60 Pain in limb (Multiple sites)	0.018	0.982	0.000
M53.8 Other specified dorsopathies	0.018	0.982	0.000
M53.2 Spinal instabilities	0.017	0.983	0.000
M79.63 Pain in limb (Forearm)	0.016	0.984	0.000
M53.1 Cervicobrachial syndrome	0.016	0.984	0.000
M53.0 Cervicocranial syndrome	0.016	0.984	0.000
M53.9 Dorsopathy, unspecified	0.015	0.985	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.014	0.986	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.014	0.986	0.000
M53.26 Spinal instabilities (Lumbar region)	0.014	0.986	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.014	0.986	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.013	0.987	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.013	0.987	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.013	0.987	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.013	0.987	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.013	0.987	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.013	0.987	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.013	0.987	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.013	0.987	0.000
M79.62 Pain in limb (Upper arm)	0.013	0.987	0.000
M53.29 Spinal instabilities (Site unspecified)	0.012	0.988	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.012	0.988	0.000
M53.24 Spinal instabilities (Thoracic region)	0.012	0.988	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.012	0.988	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.012	0.988	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.012	0.988	0.000
M53.22 Spinal instabilities (Cervical region)	0.012	0.988	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.012	0.988	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.012	0.988	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.011	0.988	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.011	0.988	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.011	0.988	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.011	0.988	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.011	0.988	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.011	0.988	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.011	0.988	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.011	0.988	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.011	0.988	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.011	0.988	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.011	0.988	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.011	0.988	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.011	0.988	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.011	0.988	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.011	0.988	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.011	0.988	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.011	0.988	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.011	0.988	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.011	0.988	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.011	0.988	0.000
M79.61 Pain in limb (Shoulder region)	0.011	0.988	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.011	0.989	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.011	0.989	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.011	0.989	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.011	0.989	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.011	0.989	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.011	0.989	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.011	0.989	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.011	0.989	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.011	0.989	0.000
M51 Other intervertebral disk disorders	0.011	0.989	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.010	0.989	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.010	0.989	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.010	0.989	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.010	0.989	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.010	0.989	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.010	0.989	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.010	0.989	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.010	0.989	0.000
Z35.5 Supervision of elderly primigravida	0.010	0.990	0.000
M51.3 Other specified intervertebral disk degeneration	0.010	0.990	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.009	0.991	0.000
N28.1 Cyst of kidney, acquired	0.009	0.991	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.009	0.991	0.000
L53.9 Erythematous condition, unspecified	0.000	0.991	0.009
J92.0 Pleural plaque with presence of asbestos	0.009	0.991	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.008	0.992	0.000
M51.9 Intervertebral disk disorder, unspecified	0.008	0.992	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.008	0.992	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.992	0.008
Z35.8 Supervision of other high-risk pregnancies	0.008	0.992	0.000
Z35 Supervision of high-risk pregnancy	0.007	0.993	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.007	0.993	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.007	0.993	0.000
M51.8 Other specified intervertebral disk disorders	0.007	0.993	0.000
M51.4 Schmorl's nodes	0.006	0.994	0.000
D11.0 Parotid gland	0.006	0.994	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.006	0.994	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.006	0.994	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.006	0.994	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.994	0.006
S92.30 Fracture of metatarsal bone (closed)	0.006	0.994	0.000
C54.1 Endometrium	0.000	0.995	0.005
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.005	0.995	0.000
Z35.6 Supervision of very young primigravida	0.005	0.995	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.005	0.995	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.005	0.995	0.000
O21.0 Mild hyperemesis gravidarum	0.005	0.995	0.000
K05.3 Chronic periodontitis	0.000	0.995	0.005
L53 Other erythematous conditions	0.000	0.995	0.005
O21 Excessive vomiting in pregnancy	0.005	0.995	0.000
E87.5 Hyperkalaemia	0.005	0.995	0.000
C51.9 Vulva, unspecified	0.000	0.995	0.005
S92.0 Fracture of calcaneus	0.005	0.995	0.000
O21.9 Vomiting of pregnancy, unspecified	0.005	0.995	0.000
S92.3 Fracture of metatarsal bone	0.005	0.995	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.005	0.995	0.000
R74.8 Abnormal levels of other serum enzymes	0.005	0.995	0.000
N26 Unspecified contracted kidney	0.004	0.995	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.004	0.996	0.000
O21.2 Late vomiting of pregnancy	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
L53.8 Other specified erythematous conditions	0.000	0.996	0.004
K12.2 Cellulitis and abscess of mouth	0.004	0.996	0.000
C51 Malignant neoplasm of vulva	0.000	0.996	0.004
C54 Malignant neoplasm of corpus uteri	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.004	0.996	0.000
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.996	0.004
L53.0 Toxic erythema	0.000	0.996	0.004
D16.4 Bones of skull and face	0.004	0.996	0.000
L53.3 Other chronic figurate erythema	0.000	0.996	0.004
L53.2 Erythema marginatum	0.000	0.996	0.004
L53.1 Erythema annulare centrifugum	0.000	0.996	0.004
O21.8 Other vomiting complicating pregnancy	0.004	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.996	0.004
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.996	0.004
N95.2 Postmenopausal atrophic vaginitis	0.004	0.996	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.996	0.000
C51-C58 Malignant neoplasms of female genital organs	0.000	0.996	0.004
N25-N29 Other disorders of kidney and ureter	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
C51.0 Labium majus	0.000	0.997	0.003
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
C56 Malignant neoplasm of ovary	0.000	0.997	0.003
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.997	0.003
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
C51.8 Overlapping lesion of vulva	0.000	0.997	0.003
C51.2 Clitoris	0.000	0.997	0.003
C54.8 Overlapping lesion of corpus uteri	0.000	0.997	0.003
C54.3 Fundus uteri	0.000	0.997	0.003
C54.2 Myometrium	0.000	0.997	0.003
C54.0 Isthmus uteri	0.000	0.997	0.003
J44.9 Chronic obstructive pulmonary disease, unspecified	0.003	0.997	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
C51.1 Labium minus	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.003	0.997	0.000
C71.1 Frontal lobe	0.000	0.997	0.003
S92.7 Multiple fractures of foot	0.003	0.997	0.000
K05.6 Periodontal disease, unspecified	0.000	0.997	0.003
C58 Malignant neoplasm of placenta	0.000	0.997	0.003
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.997	0.003
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
R01 Cardiac murmurs and other cardiac sounds	0.000	0.997	0.003
D37.4 Colon	0.003	0.997	0.000
K12 Stomatitis and related lesions	0.003	0.997	0.000
J92 Pleural plaque	0.003	0.997	0.000
S00.0 Superficial injury of scalp	0.000	0.997	0.003
R74 Abnormal serum enzyme levels	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.997	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.997	0.003
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.002	0.997	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
C57.9 Female genital organ, unspecified	0.000	0.997	0.003
I97.0 Postcardiotomy syndrome	0.000	0.997	0.002
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.002	0.997	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.997	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.997	0.002
N28.0 Ischaemia and infarction of kidney	0.002	0.997	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.998	0.002
K12.0 Recurrent oral aphthae	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
N25 Disorders resulting from impaired renal tubular function	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
N29.0 Late syphilis of kidney	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
C54.9 Corpus uteri, unspecified	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
K05 Gingivitis and periodontal diseases	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
C57.7 Other specified female genital organs	0.000	0.998	0.002
C57.4 Uterine adnexa, unspecified	0.000	0.998	0.002
C57.3 Parametrium	0.000	0.998	0.002
C57.2 Round ligament	0.000	0.998	0.002
C57.1 Broad ligament	0.000	0.998	0.002
K12.1 Other forms of stomatitis	0.002	0.998	0.000
N30.2 Other chronic cystitis	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.002
R01.2 Other cardiac sounds	0.000	0.998	0.002
K04.4 Acute apical periodontitis of pulpal origin	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
C57.8 Overlapping lesion of female genital organs	0.000	0.998	0.002
N34.2 Other urethritis	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M54.84 Other dorsalgia (Thoracic region)	0.002	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
R74.9 Abnormal level of unspecified serum enzyme	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
C52 Malignant neoplasm of vagina	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
M54.8 Other dorsalgia	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54 Dorsalgia	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
K05.0 Acute gingivitis	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.002	0.998	0.000
N25.0 Renal osteodystrophy	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
N25.1 Nephrogenic diabetes insipidus	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
K66 Other disorders of peritoneum	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.002	0.998	0.000
C57.0 Fallopian tube	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
K05.2 Acute periodontitis	0.000	0.998	0.002
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
D11 Benign neoplasm of major salivary glands	0.002	0.998	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
J46 Status asthmaticus	0.002	0.998	0.000
N27 Small kidney of unknown cause	0.002	0.998	0.000
J40-J47 Chronic lower respiratory diseases	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
M24.14 Other articular cartilage disorders (Hand)	0.000	0.998	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.998	0.002
M24.18 Other articular cartilage disorders (Other)	0.000	0.998	0.002
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.998	0.002
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
K65.8 Other peritonitis	0.000	0.998	0.002
K66.1 Haemoperitoneum	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.000	0.998	0.002
C53.1 Exocervix	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
L05 Pilonidal cyst	0.000	0.998	0.002
M54.85 Other dorsalgia (Thoracolumbar region)	0.002	0.998	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.82 Other dorsalgia (Cervical region)	0.002	0.998	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.0 Panniculitis affecting regions of neck and back	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.002
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
M54.19 Radiculopathy (Site unspecified)	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
K05.5 Other periodontal diseases	0.000	0.998	0.002
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.998	0.002
M54.1 Radiculopathy	0.002	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
K05.22 Aggressive periodontitis, generalized	0.000	0.998	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
K05.4 Periodontosis	0.000	0.998	0.001
T80.6 Other serum reactions	0.000	0.998	0.002
T80.5 Anaphylactic shock due to serum	0.000	0.998	0.002
T80.4 Rh incompatibility reaction	0.000	0.998	0.002
T80.3 ABO incompatibility reaction	0.000	0.998	0.002
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
M79.9 Soft tissue disorder, unspecified	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
D23.9 Skin, unspecified	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.998	0.000
C69.6 Orbit	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
M02.39 Reiter's disease (Site unspecified)	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.002	0.998	0.000
K65.0 Acute peritonitis	0.000	0.998	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.998	0.000
C53.0 Endocervix	0.000	0.998	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.998	0.000
T01.8 Open wounds involving other combinations of body regions	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
A69.9 Spirochaetal infection, unspecified	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.001	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.001	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.001
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
K65 Peritonitis	0.000	0.998	0.002
M25.82 Other specified joint disorders (Upper arm)	0.001	0.998	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.001	0.998	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.001	0.998	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.001	0.998	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.001	0.998	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.001	0.998	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.001	0.998	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.001	0.998	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.001	0.998	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.001	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.001	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
M79.3 Panniculitis, unspecified	0.001	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
D11.9 Major salivary gland, unspecified	0.001	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
M79.1 Myalgia	0.002	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.998	0.000
N27.9 Small kidney, unspecified	0.001	0.998	0.001
N27.1 Small kidney, bilateral	0.001	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.001
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.001
Z32.1 Pregnancy confirmed	0.001	0.998	0.000
J41 Simple and mucopurulent chronic bronchitis	0.001	0.998	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.001	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.001	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.001	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.001	0.998	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.001	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.001
S43.2 Dislocation of sternoclavicular joint	0.001	0.998	0.000
S91.3 Open wound of other parts of foot	0.001	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.999	0.001
M79.93 Soft tissue disorder, unspecified (Forearm)	0.001	0.999	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.001	0.999	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.001	0.999	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.001	0.999	0.000
H18.4 Corneal degeneration	0.000	0.999	0.001
N81.3 Complete uterovaginal prolapse	0.001	0.999	0.000
O34.6 Maternal care for abnormality of vagina	0.001	0.999	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M21.3 Wrist or foot drop (acquired)	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.001	0.999	0.000
D11.7 Other major salivary glands	0.001	0.999	0.000
M54.6 Pain in thoracic spine	0.001	0.999	0.000
N27.0 Small kidney, unilateral	0.001	0.999	0.001
U81.0 Vancomycin resistant agent	0.000	0.999	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.999	0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.001	0.999	0.000
M96.5 Postradiation scoliosis	0.001	0.999	0.000
M96.4 Postsurgical lordosis	0.001	0.999	0.000
M96.3 Postlaminectomy kyphosis	0.001	0.999	0.000
M96.2 Postradiation kyphosis	0.001	0.999	0.000
O34.0 Maternal care for congenital malformation of uterus	0.001	0.999	0.000
T94.1 Sequelae of injuries, not specified by body region	0.001	0.999	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.999	0.001
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.001	0.999	0.000
M79.2 Neuralgia and neuritis, unspecified	0.001	0.999	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
Z97 Presence of other devices	0.000	0.999	0.001
M25.77 Osteophyte (Ankle and foot)	0.001	0.999	0.000
M25.88 Other specified joint disorders (Other)	0.001	0.999	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.001	0.999	0.000
M79.39 Panniculitis, unspecified (Site unspecified)	0.001	0.999	0.000
M79.38 Panniculitis, unspecified (Other)	0.001	0.999	0.000
M79.37 Panniculitis, unspecified (Ankle and foot)	0.001	0.999	0.000
M79.36 Panniculitis, unspecified (Lower leg)	0.001	0.999	0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M79.34 Panniculitis, unspecified (Hand)	0.001	0.999	0.000
M79.33 Panniculitis, unspecified (Forearm)	0.001	0.999	0.000
M79.32 Panniculitis, unspecified (Upper arm)	0.001	0.999	0.000
M79.31 Panniculitis, unspecified (Shoulder region)	0.001	0.999	0.000
M79.30 Panniculitis, unspecified (Multiple sites)	0.001	0.999	0.000
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
S43.5 Sprain and strain of acromioclavicular joint	0.001	0.999	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
M79.17 Myalgia (Ankle and foot)	0.001	0.999	0.000
M79.14 Myalgia (Hand)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations