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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs454182
log Bayes Factor = 5.87388
Chromosome 6   position 28,511,164  (GRCh37) Explore rs454182 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.017 0.983
K90 Intestinal malabsorption
0.000 0.324 0.676
K90.9 Intestinal malabsorption, unspecified
0.000 0.400 0.600
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.508 0.492
K90.8 Other intestinal malabsorption
0.000 0.514 0.486
K90.3 Pancreatic steatorrhoea
0.000 0.515 0.485
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.515 0.485
K90.1 Tropical sprue
0.000 0.515 0.485
E83 Disorders of mineral metabolism
0.000 0.717 0.283
E83.3 Disorders of phosphorus metabolism
0.000 0.780 0.220
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.797 0.203
E83.8 Other disorders of mineral metabolism
0.000 0.797 0.203
E83.2 Disorders of zinc metabolism
0.000 0.797 0.203
E83.0 Disorders of copper metabolism
0.000 0.797 0.203
E83.4 Disorders of magnesium metabolism
0.000 0.820 0.180
E83.5 Disorders of calcium metabolism
0.000 0.888 0.112
K90-K93 Other diseases of the digestive system
0.000 0.901 0.099
E80.4 Gilbert's syndrome
0.000 0.927 0.073
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.929 0.071
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.936 0.064
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.942 0.058
K91.3 Postoperative intestinal obstruction
0.000 0.946 0.054
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.947 0.053
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.949 0.051
K93.1 Megacolon in Chagas' disease
0.000 0.949 0.051
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.949 0.051
K91.5 Postcholecystectomy syndrome
0.000 0.949 0.051
E70-E90 Metabolic disorders
0.000 0.953 0.047
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.955 0.044
E80.6 Other disorders of bilirubin metabolism
0.000 0.957 0.043
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.957 0.043
K91.1 Postgastric surgery syndromes
0.000 0.958 0.042
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.958 0.042
E80.5 Crigler-Najjar syndrome
0.000 0.958 0.042
E80.3 Defects of catalase and peroxydase
0.000 0.958 0.042
E80.2 Other porphyria
0.000 0.958 0.042
E80.1 Porphyria cutanea tarda
0.000 0.958 0.042
E80.0 Hereditary erythropoietic porphyria
0.000 0.958 0.042
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.962 0.038
E79 Disorders of purine and pyrimidine metabolism
0.000 0.964 0.035
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.966 0.034
E77 Disorders of glycoprotein metabolism
0.000 0.966 0.034
E76 Disorders of glycosaminoglycan metabolism
0.000 0.966 0.034
E72 Other disorders of amino-acid metabolism
0.000 0.966 0.034
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.966 0.034
E70 Disorders of aromatic amino-acid metabolism
0.000 0.966 0.034
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.966 0.034
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.966 0.034
E84 Cystic fibrosis
0.000 0.968 0.032
E89.3 Postprocedural hypopituitarism
0.000 0.968 0.032
E74 Other disorders of carbohydrate metabolism
0.000 0.968 0.032
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.972 0.028
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.972 0.028
E89.5 Postprocedural testicular hypofunction
0.000 0.972 0.028
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.973 0.027
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.973 0.027
E89.2 Postprocedural hypoparathyroidism
0.000 0.973 0.027
E73 Lactose intolerance
0.000 0.973 0.027
E89.1 Postprocedural hypoinsulinaemia
0.000 0.974 0.026
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.974 0.026
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.974 0.026
E79.1 Lesch-Nyhan syndrome
0.000 0.974 0.026
E89.4 Postprocedural ovarian failure
0.000 0.974 0.025
E85 Amyloidosis
0.000 0.975 0.025
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.975 0.025
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.975 0.025
E70.3 Albinism
0.000 0.975 0.025
E70.2 Disorders of tyrosine metabolism
0.000 0.975 0.025
E70.1 Other hyperphenylalaninaemias
0.000 0.975 0.025
E70.0 Classical phenylketonuria
0.000 0.975 0.025
E71.3 Disorders of fatty-acid metabolism
0.000 0.975 0.025
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.975 0.025
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.975 0.025
E71.0 Maple-syrup-urine disease
0.000 0.975 0.025
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.975 0.025
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.975 0.025
E72.5 Disorders of glycine metabolism
0.000 0.975 0.025
E72.4 Disorders of ornithine metabolism
0.000 0.975 0.025
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.975 0.025
E72.2 Disorders of urea cycle metabolism
0.000 0.975 0.025
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.975 0.025
E72.0 Disorders of amino-acid transport
0.000 0.975 0.025
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.975 0.025
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.975 0.025
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.975 0.025
E76.2 Other mucopolysaccharidoses
0.000 0.975 0.025
E76.1 Mucopolysaccharidosis, type II
0.000 0.975 0.025
E76.0 Mucopolysaccharidosis, type I
0.000 0.975 0.025
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.975 0.025
E77.8 Other disorders of glycoprotein metabolism
0.000 0.975 0.025
E77.1 Defects in glycoprotein degradation
0.000 0.975 0.025
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.975 0.025
E84.8 Cystic fibrosis with other manifestations
0.000 0.977 0.023
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.977 0.023
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.977 0.023
K91.4 Colostomy and enterostomy malfunction
0.000 0.977 0.023
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.023
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.023
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.023
E74.2 Disorders of galactose metabolism
0.000 0.977 0.023
E74.1 Disorders of fructose metabolism
0.000 0.977 0.023
E74.0 Glycogen storage disease
0.000 0.977 0.023
E89.0 Postprocedural hypothyroidism
0.000 0.978 0.022
E84.9 Cystic fibrosis, unspecified
0.000 0.978 0.021
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.979 0.020
E75.6 Lipid storage disorder, unspecified
0.000 0.980 0.019
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.980 0.019
E75.3 Sphingolipidosis, unspecified
0.000 0.980 0.019
E75.1 Other gangliosidosis
0.000 0.980 0.019
E75.0 GM2 gangliosidosis
0.000 0.980 0.019
E73.8 Other lactose intolerance
0.000 0.980 0.019
E73.1 Secondary lactase deficiency
0.000 0.980 0.019
E73.0 Congenital lactase deficiency
0.000 0.980 0.019
E85.9 Amyloidosis, unspecified
0.000 0.981 0.019
E85.8 Other amyloidosis
0.000 0.982 0.018
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E75.2 Other sphingolipidosis
0.000 0.983 0.017
E85.3 Secondary systemic amyloidosis
0.000 0.984 0.016
E75.5 Other lipid storage disorders
0.000 0.984 0.016
E88 Other metabolic disorders
0.001 0.986 0.013
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.986 0.014
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.988 0.012
E73.9 Lactose intolerance, unspecified
0.000 0.988 0.012
E85.4 Organ-limited amyloidosis
0.000 0.988 0.012
E78.8 Other disorders of lipoprotein metabolism
0.000 0.989 0.011
E78.6 Lipoprotein deficiency
0.000 0.989 0.011
E55.9 Vitamin D deficiency, unspecified
0.000 0.990 0.010
E88.8 Other specified metabolic disorders
0.001 0.990 0.010
E78.3 Hyperchylomicronaemia
0.000 0.990 0.010
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.990 0.009
E78.4 Other hyperlipidaemia
0.000 0.990 0.010
E88.9 Metabolic disorder, unspecified
0.001 0.991 0.009
M13.00 Polyarthritis, unspecified (Multiple sites)
0.009 0.991 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.991 0.009
E88.3 Tumour lysis syndrome
0.001 0.991 0.009
E88.2 Lipomatosis, not elsewhere classified
0.001 0.992 0.008
E55 Vitamin D deficiency
0.000 0.993 0.007
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.993 0.007
E78.1 Pure hyperglyceridaemia
0.000 0.994 0.006
E27.1 Primary adrenocortical insufficiency
0.000 0.994 0.006
M13.0 Polyarthritis, unspecified
0.006 0.994 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.005 0.995 0.000
E55.0 Rickets, active
0.000 0.995 0.005
C80.9 Malignant neoplasm, unspecified
0.000 0.995 0.005
K92 Other diseases of digestive system
0.000 0.995 0.005
C80 Malignant neoplasm without specification of site
0.000 0.995 0.005
E50-E64 Other nutritional deficiencies
0.000 0.995 0.005
S72.30 Fracture of shaft of femur (closed)
0.005 0.995 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.995 0.005
M13.08 Polyarthritis, unspecified (Other)
0.004 0.995 0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.004 0.995 0.000
M13.06 Polyarthritis, unspecified (Lower leg)
0.004 0.995 0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.004 0.995 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.004 0.995 0.000
M13.03 Polyarthritis, unspecified (Forearm)
0.004 0.995 0.000
M13.02 Polyarthritis, unspecified (Upper arm)
0.004 0.995 0.000
M13.01 Polyarthritis, unspecified (Shoulder region)
0.004 0.995 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.995 0.005
R04.0 Epistaxis
0.005 0.995 0.000
K92.9 Disease of digestive system, unspecified
0.000 0.996 0.004
R80 Isolated proteinuria
0.004 0.996 0.000
E27 Other disorders of adrenal gland
0.000 0.996 0.004
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.996 0.004
J35.0 Chronic tonsillitis
0.004 0.996 0.000
Z88.2 Personal history of allergy to sulphonamides
0.004 0.996 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.996 0.003
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.996 0.004
E63 Other nutritional deficiencies
0.000 0.996 0.004
E56 Other vitamin deficiencies
0.000 0.996 0.004
E51 Thiamine deficiency
0.000 0.996 0.004
E50 Vitamin A deficiency
0.000 0.996 0.004
E60 Dietary zinc deficiency
0.000 0.996 0.004
E59 Dietary selenium deficiency
0.000 0.996 0.004
E58 Dietary calcium deficiency
0.000 0.996 0.004
E54 Ascorbic acid deficiency
0.000 0.996 0.004
E52 Niacin deficiency [pellagra]
0.000 0.996 0.004
Y42.5 Other oestrogens and progestogens
0.000 0.996 0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.996 0.004
S99.9 Unspecified injury of ankle and foot
0.003 0.997 0.000
N39.8 Other specified disorders of urinary system
0.003 0.997 0.000
C77.1 Intrathoracic lymph nodes
0.000 0.997 0.003
R06.8 Other and unspecified abnormalities of breathing
0.003 0.997 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.997 0.003
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.997 0.003
E27.0 Other adrenocortical overactivity
0.000 0.997 0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.003 0.997 0.000
K92.8 Other specified diseases of digestive system
0.000 0.997 0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.997 0.003
M94.86 Other specified disorders of cartilage (Lower leg)
0.000 0.997 0.003
E40-E46 Malnutrition
0.000 0.997 0.003
E27.8 Other specified disorders of adrenal gland
0.000 0.997 0.003
G24.9 Dystonia, unspecified
0.000 0.997 0.003
E61 Deficiency of other nutrient elements
0.000 0.997 0.003
E27.2 Addisonian crisis
0.000 0.997 0.003
E50.9 Vitamin A deficiency, unspecified
0.000 0.997 0.003
E50.8 Other manifestations of vitamin A deficiency
0.000 0.997 0.003
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.997 0.003
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.997 0.003
E50.5 Vitamin A deficiency with night blindness
0.000 0.997 0.003
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.997 0.003
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.997 0.003
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.997 0.003
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.997 0.003
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.997 0.003
E51.9 Thiamine deficiency, unspecified
0.000 0.997 0.003
E51.8 Other manifestations of thiamine deficiency
0.000 0.997 0.003
E51.1 Beriberi
0.000 0.997 0.003
E56.9 Vitamin deficiency, unspecified
0.000 0.997 0.003
E56.8 Deficiency of other vitamins
0.000 0.997 0.003
E56.1 Deficiency of vitamin K
0.000 0.997 0.003
E56.0 Deficiency of vitamin E
0.000 0.997 0.003
E63.9 Nutritional deficiency, unspecified
0.000 0.997 0.003
E63.8 Other specified nutritional deficiencies
0.000 0.997 0.003
E63.1 Imbalance of constituents of food intake
0.000 0.997 0.003
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.997 0.003
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.997 0.003
E64.8 Sequelae of other nutritional deficiencies
0.000 0.997 0.003
E64.3 Sequelae of rickets
0.000 0.997 0.003
E64.2 Sequelae of vitamin C deficiency
0.000 0.997 0.003
E64.1 Sequelae of vitamin A deficiency
0.000 0.997 0.003
E64.0 Sequelae of protein-energy malnutrition
0.000 0.997 0.003
R68.8 Other specified general symptoms and signs
0.000 0.997 0.003
E51.2 Wernicke's encephalopathy
0.000 0.997 0.003
E16 Other disorders of pancreatic internal secretion
0.000 0.997 0.003
E15 Nondiabetic hypoglycaemic coma
0.000 0.997 0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.997 0.003
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.997 0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.000 0.997 0.003
E20-E35 Disorders of other endocrine glands
0.000 0.997 0.003
R77.8 Other specified abnormalities of plasma proteins
0.003 0.997 0.000
S72.3 Fracture of shaft of femur
0.003 0.997 0.000
G24.5 Blepharospasm
0.000 0.997 0.003
S02.80 Fractures of other skull and facial bones (closed)
0.003 0.997 0.000
E16.1 Other hypoglycaemia
0.000 0.997 0.003
G24 Dystonia
0.000 0.997 0.003
S72.31 Fracture of shaft of femur (open)
0.002 0.997 0.000
G24.3 Spasmodic torticollis
0.000 0.997 0.002
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.997 0.002
E45 Retarded development following protein-energy malnutrition
0.000 0.997 0.002
E43 Unspecified severe protein-energy malnutrition
0.000 0.997 0.002
E42 Marasmic kwashiorkor
0.000 0.997 0.002
E41 Nutritional marasmus
0.000 0.997 0.002
E40 Kwashiorkor
0.000 0.997 0.002
E86 Volume depletion
0.000 0.997 0.003
E61.2 Magnesium deficiency
0.000 0.997 0.002
E22.0 Acromegaly and pituitary gigantism
0.000 0.998 0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.002 0.998 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.998 0.002
E61.8 Deficiency of other specified nutrient elements
0.000 0.998 0.002
E61.7 Deficiency of multiple nutrient elements
0.000 0.998 0.002
E61.6 Vanadium deficiency
0.000 0.998 0.002
E61.5 Molybdenum deficiency
0.000 0.998 0.002
E61.4 Chromium deficiency
0.000 0.998 0.002
E61.3 Manganese deficiency
0.000 0.998 0.002
E61.0 Copper deficiency
0.000 0.998 0.002
S99 Other and unspecified injuries of ankle and foot
0.002 0.998 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.002 0.998 0.000
J92.0 Pleural plaque with presence of asbestos
0.000 0.998 0.002
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.998 0.002
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.998 0.002
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.998 0.002
E16.4 Abnormal secretion of gastrin
0.000 0.998 0.002
E16.3 Increased secretion of glucagon
0.000 0.998 0.002
M21.24 Flexion deformity (Hand)
0.002 0.998 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.998 0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.998 0.002
C85.1 B-cell lymphoma, unspecified
0.000 0.998 0.002
C85.0 Lymphosarcoma
0.000 0.998 0.002
R45.2 Unhappiness
0.000 0.998 0.002
R68.0 Hypothermia, not associated with low environmental temperature
0.000 0.998 0.002
E22 Hyperfunction of pituitary gland
0.000 0.998 0.002
R45.1 Restlessness and agitation
0.000 0.998 0.002
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.998 0.002
E32 Diseases of thymus
0.000 0.998 0.002
E31 Polyglandular dysfunction
0.000 0.998 0.002
E30 Disorders of puberty, not elsewhere classified
0.000 0.998 0.002
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.998 0.002
Y45.0 Opioids and related analgesics
0.002 0.998 0.000
Z90.5 Acquired absence of kidney
0.000 0.998 0.002
E25 Adrenogenital disorders
0.000 0.998 0.002
E34 Other endocrine disorders
0.000 0.998 0.002
E26 Hyperaldosteronism
0.000 0.998 0.002
G24.4 Idiopathic orofacial dystonia
0.000 0.998 0.002
G24.2 Idiopathic nonfamilial dystonia
0.000 0.998 0.002
G24.1 Idiopathic familial dystonia
0.000 0.998 0.002
G24.0 Drug-induced dystonia
0.000 0.998 0.002
E00-E07 Disorders of thyroid gland
0.000 0.998 0.002
S99.8 Other specified injuries of ankle and foot
0.002 0.998 0.000
G47.4 Narcolepsy and cataplexy
0.002 0.998 0.000
E24 Cushing's syndrome
0.000 0.998 0.002
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.002 0.998 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.998 0.002
R68 Other general symptoms and signs
0.000 0.998 0.002
E27.9 Disorder of adrenal gland, unspecified
0.000 0.998 0.002
E44.1 Mild protein-energy malnutrition
0.000 0.998 0.002
E44.0 Moderate protein-energy malnutrition
0.000 0.998 0.002
G24.8 Other dystonia
0.000 0.998 0.002
C83.3 Large cell (diffuse)
0.000 0.998 0.002
E24.2 Drug-induced Cushing's syndrome
0.000 0.998 0.002
M54.36 Sciatica (Lumbar region)
0.002 0.998 0.000
E53 Deficiency of other B group vitamins
0.000 0.998 0.002
E34.9 Endocrine disorder, unspecified
0.000 0.998 0.002
C82.2 Large cell, follicular
0.000 0.998 0.002
E28 Ovarian dysfunction
0.000 0.998 0.002
S99.7 Multiple injuries of ankle and foot
0.002 0.998 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.998 0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.998 0.002
E05.5 Thyroid crisis or storm
0.000 0.998 0.002
E05.4 Thyrotoxicosis factitia
0.000 0.998 0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.998 0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.998 0.002
J32.9 Chronic sinusitis, unspecified
0.002 0.998 0.000
E20 Hypoparathyroidism
0.000 0.998 0.002
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.002 0.998 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.998 0.002
E22.8 Other hyperfunction of pituitary gland
0.000 0.998 0.002
S30.1 Contusion of abdominal wall
0.000 0.998 0.002
E30.9 Disorder of puberty, unspecified
0.000 0.998 0.002
E30.8 Other disorders of puberty
0.000 0.998 0.002
E30.1 Precocious puberty
0.000 0.998 0.002
E30.0 Delayed puberty
0.000 0.998 0.002
E31.9 Polyglandular dysfunction, unspecified
0.000 0.998 0.002
E31.8 Other polyglandular dysfunction
0.000 0.998 0.002
E31.1 Polyglandular hyperfunction
0.000 0.998 0.002
E31.0 Autoimmune polyglandular failure
0.000 0.998 0.002
E32.9 Disease of thymus, unspecified
0.000 0.998 0.002
E32.8 Other diseases of thymus
0.000 0.998 0.002
E32.1 Abscess of thymus
0.000 0.998 0.002
E32.0 Persistent hyperplasia of thymus
0.000 0.998 0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.998 0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.998 0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.998 0.002
M21.3 Wrist or foot drop (acquired)
0.002 0.998 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.002 0.998 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.998 0.002
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.998 0.002
E22.1 Hyperprolactinaemia
0.000 0.998 0.002
E25.9 Adrenogenital disorder, unspecified
0.000 0.998 0.002
E25.8 Other adrenogenital disorders
0.000 0.998 0.002
E34.5 Androgen resistance syndrome
0.000 0.998 0.002
E34.4 Constitutional tall stature
0.000 0.998 0.002
E34.3 Short stature, not elsewhere classified
0.000 0.998 0.002
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.998 0.002
E34.1 Other hypersecretion of intestinal hormones
0.000 0.998 0.002
E34.0 Carcinoid syndrome
0.000 0.998 0.002
R68.2 Dry mouth, unspecified
0.000 0.998 0.002
E05.8 Other thyrotoxicosis
0.000 0.998 0.002
E26.9 Hyperaldosteronism, unspecified
0.000 0.998 0.002
E26.8 Other hyperaldosteronism
0.000 0.998 0.002
E26.1 Secondary hyperaldosteronism
0.000 0.998 0.002
M21.2 Flexion deformity
0.002 0.998 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.998 0.002
I72.4 Aneurysm of artery of lower extremity
0.002 0.998 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.998 0.002
G47.8 Other sleep disorders
0.002 0.998 0.000
R45.0 Nervousness
0.000 0.998 0.002
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.998 0.002
E29 Testicular dysfunction
0.000 0.998 0.002
E16.2 Hypoglycaemia, unspecified
0.000 0.998 0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.998 0.002
E00 Congenital iodine-deficiency syndrome
0.000 0.998 0.002
C82.0 Small cleaved cell, follicular
0.000 0.998 0.002
E24.8 Other Cushing's syndrome
0.000 0.998 0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.998 0.002
E24.3 Ectopic ACTH syndrome
0.000 0.998 0.002
E24.1 Nelson's syndrome
0.000 0.998 0.002
R45 Symptoms and signs involving emotional state
0.000 0.998 0.002
C82.6 Cutaneous follicle centre lymphoma
0.000 0.998 0.002
C82.5 Diffuse follicle centre lymphoma
0.000 0.998 0.002
C82.4 Follicular lymphoma grade IIIb
0.000 0.998 0.002
E24.0 Pituitary-dependent Cushing's disease
0.000 0.998 0.002
M20.2 Hallux rigidus
0.002 0.998 0.000
R68.3 Clubbing of fingers
0.000 0.998 0.002
R68.1 Nonspecific symptoms peculiar to infancy
0.000 0.998 0.002
M21.76 Unequal limb length (acquired) (Lower leg)
0.002 0.998 0.000
E26.0 Primary hyperaldosteronism
0.000 0.998 0.002
K75.4 Autoimmune hepatitis
0.000 0.998 0.002
T81.9 Unspecified complication of procedure
0.002 0.998 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.998 0.002
E53.1 Pyridoxine deficiency
0.000 0.998 0.001
E53.0 Riboflavin deficiency
0.000 0.998 0.001
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.000 0.998 0.002
E28.3 Primary ovarian failure
0.000 0.998 0.002
E28.9 Ovarian dysfunction, unspecified
0.000 0.998 0.002
E28.8 Other ovarian dysfunction
0.000 0.998 0.002
E28.1 Androgen excess
0.000 0.998 0.002
E28.0 Oestrogen excess
0.000 0.998 0.002
S60.9 Superficial injury of wrist and hand, unspecified
0.000 0.998 0.002
E20.8 Other hypoparathyroidism
0.000 0.998 0.001
E20.1 Pseudohypoparathyroidism
0.000 0.998 0.001
E20.0 Idiopathic hypoparathyroidism
0.000 0.998 0.001
M13.80 Other specified arthritis (Multiple sites)
0.002 0.998 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.998 0.002
M21.7 Unequal limb length (acquired)
0.002 0.998 0.000
S81.8 Open wound of other parts of lower leg
0.002 0.998 0.000
M21.27 Flexion deformity (Ankle and foot)
0.002 0.998 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.001 0.998 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.001 0.998 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.001 0.998 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.001 0.998 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.001 0.998 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.001 0.998 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.001 0.998 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.001 0.998 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.001 0.998 0.000
E34.8 Other specified endocrine disorders
0.000 0.998 0.001
M21.29 Flexion deformity (Site unspecified)
0.001 0.998 0.000
M21.28 Flexion deformity (Other)
0.001 0.998 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.001 0.998 0.000
M21.23 Flexion deformity (Forearm)
0.001 0.998 0.000
M21.22 Flexion deformity (Upper arm)
0.001 0.998 0.000
M21.21 Flexion deformity (Shoulder region)
0.001 0.998 0.000
M21.20 Flexion deformity (Multiple sites)
0.001 0.998 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.002 0.998 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.002 0.998 0.000
C82.3 Follicular lymphoma grade IIIa
0.000 0.998 0.001
F41.1 Generalised anxiety disorder
0.002 0.998 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.002 0.998 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.998 0.001
E29.8 Other testicular dysfunction
0.000 0.998 0.001
E29.0 Testicular hyperfunction
0.000 0.998 0.001
R03.1 Nonspecific low blood-pressure reading
0.000 0.998 0.002
R45.6 Physical violence
0.000 0.998 0.002
M13 Other arthritis
0.002 0.998 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.998 0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.998 0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.998 0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.998 0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.998 0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.998 0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.998 0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.998 0.001
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.998 0.002
M13.8 Other specified arthritis
0.001 0.998 0.000
R45.3 Demoralisation and apathy
0.000 0.998 0.001
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.001 0.998 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.998 0.001
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.998 0.002
R45.5 Hostility
0.000 0.998 0.001
S90.8 Other superficial injuries of ankle and foot
0.002 0.998 0.000
M21.4 Flat foot [pes planus] (acquired)
0.001 0.998 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.002 0.998 0.000
Z99.2 Dependence on renal dialysis
0.000 0.998 0.002
E67 Other hyperalimentation
0.000 0.998 0.001
E68 Sequelae of hyperalimentation
0.000 0.998 0.001
M21.26 Flexion deformity (Lower leg)
0.001 0.998 0.000
D04.5 Skin of trunk
0.000 0.998 0.002
R45.4 Irritability and anger
0.000 0.998 0.001
E04 Other non-toxic goitre
0.000 0.998 0.001
E23 Hypofunction and other disorders of pituitary gland
0.000 0.998 0.001
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.002 0.998 0.000
S02.8 Fractures of other skull and facial bones
0.001 0.998 0.000
Z99.8 Dependence on other enabling machines and devices
0.000 0.998 0.001
Z99.1 Dependence on respirator
0.000 0.998 0.001
M21 Other acquired deformities of limbs
0.001 0.998 0.000
M13.86 Other specified arthritis (Lower leg)
0.001 0.999 0.000
M21.79 Unequal limb length (acquired) (Site unspecified)
0.001 0.999 0.000
M21.78 Unequal limb length (acquired)-Other
0.001 0.999 0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.001 0.999 0.000
M21.74 Unequal limb length (acquired) (Hand)
0.001 0.999 0.000
M21.73 Unequal limb length (acquired) (Forearm)
0.001 0.999 0.000
M21.72 Unequal limb length (acquired) (Upper arm)
0.001 0.999 0.000
M21.71 Unequal limb length (acquired)-Shldr region
0.001 0.999 0.000
M21.70 Unequal limb length (acquired) (Multiple sites)
0.001 0.999 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.000 0.999 0.001
H25.1 Senile nuclear cataract
0.001 0.999 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.000 0.999 0.001
M71.38 Other bursal cyst (Other)
0.000 0.999 0.001
E05.9 Thyrotoxicosis, unspecified
0.000 0.999 0.001
R45.7 State of emotional shock and stress, unspecified
0.000 0.999 0.001
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.000 0.999 0.001
I45.6 Preexcitation syndrome
0.001 0.999 0.000
M14.6 Neuropathic arthropathy
0.001 0.999 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.999 0.001
D16.2 Long bones of lower limb
0.000 0.999 0.001
E11.2 With renal complications
0.000 0.999 0.001
M21.8 Other specified acquired deformities of limbs
0.001 0.999 0.000
S80.8 Other superficial injuries of lower leg
0.000 0.999 0.001
M13.88 Other specified arthritis (Other)
0.001 0.999 0.000
M13.87 Other specified arthritis (Ankle and foot)
0.001 0.999 0.000
M13.85 Other specified arthritis (Pelvic region and thigh)
0.001 0.999 0.000
M13.84 Other specified arthritis (Hand)
0.001 0.999 0.000
M13.83 Other specified arthritis (Forearm)
0.001 0.999 0.000
M13.82 Other specified arthritis (Upper arm)
0.001 0.999 0.000
M13.81 Other specified arthritis (Shoulder region)
0.001 0.999 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.001 0.999 0.000
D16.3 Short bones of lower limb
0.000 0.999 0.001
G47 Sleep disorders
0.001 0.999 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.001 0.999 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.001 0.999 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.001 0.999 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.001 0.999 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.001 0.999 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.001 0.999 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.001 0.999 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.001 0.999 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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