TreeWAS – Variant ID: rs4575545

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04 Other non-toxic goitre	0.995	0.005	0.000
E04.2 Non-toxic multinodular goitre	0.994	0.006	0.000
E04.9 Non-toxic goitre, unspecified	0.994	0.006	0.000
E00-E07 Disorders of thyroid gland	0.981	0.019	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.972	0.028	0.000
E05.9 Thyrotoxicosis, unspecified	0.939	0.061	0.000
E05.8 Other thyrotoxicosis	0.901	0.099	0.000
E07 Other disorders of thyroid	0.894	0.106	0.000
E07.9 Disorder of thyroid, unspecified	0.791	0.209	0.000
E04.0 Non-toxic diffuse goitre	0.752	0.248	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.748	0.252	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.745	0.255	0.000
E07.8 Other specified disorders of thyroid	0.743	0.257	0.000
E04.8 Other specified non-toxic goitre	0.713	0.286	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.710	0.289	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.703	0.297	0.000
E00 Congenital iodine-deficiency syndrome	0.703	0.297	0.000
E05.5 Thyroid crisis or storm	0.697	0.303	0.000
E05.4 Thyrotoxicosis factitia	0.697	0.303	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.697	0.303	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.690	0.310	0.000
E06 Thyroiditis	0.689	0.311	0.000
E03 Other hypothyroidism	0.678	0.322	0.000
E07.1 Dyshormogenetic goitre	0.641	0.359	0.000
E07.0 Hypersecretion of calcitonin	0.641	0.359	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.565	0.435	0.000
E03.8 Other specified hypothyroidism	0.549	0.451	0.000
E06.3 Autoimmune thyroiditis	0.543	0.457	0.000
E04.1 Non-toxic single thyroid nodule	0.524	0.476	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.521	0.479	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.504	0.496	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.504	0.496	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.504	0.496	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.504	0.496	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.504	0.496	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.504	0.496	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.504	0.496	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.504	0.496	0.000
E06.5 Other chronic thyroiditis	0.494	0.506	0.000
E06.4 Drug-induced thyroiditis	0.494	0.506	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.494	0.506	0.000
E06.0 Acute thyroiditis	0.494	0.506	0.000
E03.5 Myxoedema coma	0.486	0.514	0.000
E03.4 Atrophy of thyroid (acquired)	0.486	0.514	0.000
E03.3 Postinfectious hypothyroidism	0.486	0.514	0.000
E03.1 Congenital hypothyroidism without goitre	0.486	0.514	0.000
E06.1 Subacute thyroiditis	0.484	0.516	0.000
E06.9 Thyroiditis, unspecified	0.423	0.577	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.296	0.704	0.000
K44 Diaphragmatic hernia	0.149	0.851	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.115	0.885	0.000
K44.1 Diaphragmatic hernia with gangrene	0.112	0.887	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.966	0.034
N99.3 Prolapse of vaginal vault after hysterectomy	0.033	0.967	0.000
S19.9 Unspecified injury of neck	0.026	0.974	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.021	0.979	0.000
B44.9 Aspergillosis, unspecified	0.015	0.985	0.000
S19 Other and unspecified injuries of neck	0.014	0.986	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.014	0.986	0.000
B44 Aspergillosis	0.012	0.988	0.000
B44.1 Other pulmonary aspergillosis	0.012	0.988	0.000
Z93.2 Ileostomy status	0.000	0.988	0.012
S19.7 Multiple injuries of neck	0.010	0.989	0.000
E03.9 Hypothyroidism, unspecified	0.010	0.990	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.990	0.010
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.010	0.990	0.000
S19.8 Other specified injuries of neck	0.009	0.991	0.000
B44.8 Other forms of aspergillosis	0.009	0.991	0.000
B44.7 Disseminated aspergillosis	0.009	0.991	0.000
B44.2 Tonsillar aspergillosis	0.009	0.991	0.000
B44.0 Invasive pulmonary aspergillosis	0.009	0.991	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.009	0.991	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.009	0.991	0.000
E10.3 With ophthalmic complications	0.000	0.991	0.009
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.009	0.991	0.000
E23.0 Hypopituitarism	0.009	0.991	0.000
N45 Orchitis and epididymitis	0.008	0.992	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.008	0.992	0.000
S10-S19 Injuries to the neck	0.008	0.992	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
E20-E35 Disorders of other endocrine glands	0.008	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.007	0.993	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.007	0.993	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.007	0.993	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.993	0.007
S10 Superficial injury of neck	0.007	0.993	0.000
G35 Multiple sclerosis	0.000	0.993	0.007
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
S11 Open wound of neck	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
E89.0 Postprocedural hypothyroidism	0.007	0.993	0.000
S10.9 Superficial injury of neck, part unspecified	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.006	0.993	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.006	0.993	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.006	0.994	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.006	0.994	0.000
E23.7 Disorder of pituitary gland, unspecified	0.006	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
S17 Crushing injury of neck	0.006	0.994	0.000
S15 Injury of blood vessels at neck level	0.006	0.994	0.000
S18 Traumatic amputation at neck level	0.006	0.994	0.000
S16 Injury of muscle and tendon at neck level	0.006	0.994	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.006	0.994	0.000
S11.8 Open wound of other parts of neck	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
S42.2 Fracture of upper end of humerus	0.000	0.994	0.006
S10.1 Other and unspecified superficial injuries of throat	0.006	0.994	0.000
S11.9 Open wound of neck, part unspecified	0.006	0.994	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E32 Diseases of thymus	0.006	0.994	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.994	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.994	0.000
S13.4 Sprain and strain of cervical spine	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.994	0.000
E27.0 Other adrenocortical overactivity	0.005	0.994	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.005	0.995	0.000
T83.2 Mechanical complication of graft of urinary organ	0.005	0.995	0.000
S10.7 Multiple superficial injuries of neck	0.005	0.995	0.000
S10.0 Contusion of throat	0.005	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.005	0.995	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.005	0.995	0.000
S11.1 Open wound involving thyroid gland	0.005	0.995	0.000
S11.0 Open wound involving larynx and trachea	0.005	0.995	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.005	0.995	0.000
S14 Injury of nerves and spinal cord at neck level	0.005	0.995	0.000
E27.2 Addisonian crisis	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
E34 Other endocrine disorders	0.005	0.995	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.005	0.995	0.000
E50-E64 Other nutritional deficiencies	0.005	0.995	0.000
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
S11.7 Multiple open wounds of neck	0.005	0.995	0.000
E40-E46 Malnutrition	0.005	0.995	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.995	0.005
S13.5 Sprain and strain of thyroid region	0.005	0.995	0.000
S13.3 Multiple dislocations of neck	0.005	0.995	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.005	0.995	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.005	0.995	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.005	0.995	0.000
E28 Ovarian dysfunction	0.005	0.995	0.000
S10.8 Superficial injury of other parts of neck	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
N48.1 Balanoposthitis	0.000	0.995	0.005
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.005	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
E29 Testicular dysfunction	0.005	0.995	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.995	0.005
K10.8 Other specified diseases of jaws	0.000	0.995	0.005
S12 Fracture of neck	0.005	0.995	0.000
Z75 Problems related to medical facilities and other health care	0.001	0.995	0.004
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
E89.2 Postprocedural hypoparathyroidism	0.005	0.995	0.000
S42 Fracture of shoulder and upper arm	0.000	0.995	0.005
N99.5 Malfunction of external stoma of urinary tract	0.005	0.995	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.004	0.995	0.000
S15.8 Injury of other blood vessels at neck level	0.004	0.995	0.000
S15.7 Injury of multiple blood vessels at neck level	0.004	0.995	0.000
S15.3 Injury of internal jugular vein	0.004	0.995	0.000
S15.2 Injury of external jugular vein	0.004	0.995	0.000
S15.1 Injury of vertebral artery	0.004	0.995	0.000
S15.0 Injury of carotid artery	0.004	0.995	0.000
S17.9 Crushing injury of neck, part unspecified	0.004	0.995	0.000
S17.8 Crushing injury of other parts of neck	0.004	0.995	0.000
S17.0 Crushing injury of larynx and traches	0.004	0.995	0.000
S42.3 Fracture of shaft of humerus	0.000	0.995	0.005
B49 Unspecified mycosis	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.995	0.000
S13.1 Dislocation of cervical vertebra	0.004	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.996	0.004
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.996	0.004
N99.0 Postprocedural renal failure	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
M11.2 Other chondrocalcinosis	0.004	0.996	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.996	0.004
N99.1 Postprocedural urethral stricture	0.004	0.996	0.000
E51 Thiamine deficiency	0.004	0.996	0.000
N99.2 Postprocedural adhesions of vagina	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
K40-K46 Hernia	0.004	0.996	0.000
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.996	0.004
E11.5 With peripheral circulatory complications	0.000	0.996	0.004
E28.3 Primary ovarian failure	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.004	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
S14.6 Injury of other and unspecified nerves of neck	0.004	0.996	0.000
S14.5 Injury of cervical sympathetic nerves	0.004	0.996	0.000
S14.4 Injury of peripheral nerves of neck	0.004	0.996	0.000
S14.2 Injury of nerve root of cervical spine	0.004	0.996	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.004	0.996	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.996	0.004
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.996	0.004
B35-B49 Mycoses	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
E89.3 Postprocedural hypopituitarism	0.004	0.996	0.000
E56 Other vitamin deficiencies	0.004	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.996	0.000
M47.1 Other spondylosis with myelopathy	0.004	0.996	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.004	0.996	0.000
E63 Other nutritional deficiencies	0.004	0.996	0.000
E50 Vitamin A deficiency	0.004	0.996	0.000
E60 Dietary zinc deficiency	0.004	0.996	0.000
E59 Dietary selenium deficiency	0.004	0.996	0.000
E58 Dietary calcium deficiency	0.004	0.996	0.000
E54 Ascorbic acid deficiency	0.004	0.996	0.000
E52 Niacin deficiency [pellagra]	0.004	0.996	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.996	0.004
K62.3 Rectal prolapse	0.000	0.996	0.004
S12.1 Fracture of second cervical vertebra	0.004	0.996	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.996	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.003	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.003	0.996	0.000
E42 Marasmic kwashiorkor	0.003	0.996	0.000
E41 Nutritional marasmus	0.003	0.996	0.000
E40 Kwashiorkor	0.003	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.996	0.004
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.996	0.004
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.996	0.004
Y83.9 Surgical procedure, unspecified	0.004	0.996	0.000
S12.8 Fracture of other parts of neck	0.003	0.996	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.001	0.996	0.003
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.996	0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.996	0.000
S14.3 Injury of brachial plexus	0.003	0.996	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.996	0.001
S14.1 Other and unspecified injuries of cervical spinal cord	0.003	0.996	0.000
S40 Superficial injury of shoulder and upper arm	0.000	0.996	0.004
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.996	0.004
S42.1 Fracture of scapula	0.000	0.996	0.003
E51.2 Wernicke's encephalopathy	0.003	0.996	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.996	0.003
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.997	0.003
S12.9 Fracture of neck, part unspecified	0.003	0.997	0.000
Z75.0 Medical services not available in home	0.001	0.997	0.003
J38.4 Oedema of larynx	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
D34 Benign neoplasm of thyroid gland	0.003	0.997	0.000
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.003	0.997	0.000
M11.28 Other chondrocalcinosis (Other)	0.003	0.997	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.003	0.997	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.003	0.997	0.000
M11.24 Other chondrocalcinosis (Hand)	0.003	0.997	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.003	0.997	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.003	0.997	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.003	0.997	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.003	0.997	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
S12.0 Fracture of first cervical vertebra	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
K42 Umbilical hernia	0.003	0.997	0.000
E89.4 Postprocedural ovarian failure	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.003	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.003	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.003	0.997	0.000
E51.1 Beriberi	0.003	0.997	0.000
S12.7 Multiple fractures of cervical spine	0.003	0.997	0.000
I70 Atherosclerosis	0.000	0.997	0.003
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.003	0.997	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.997	0.003
B48 Other mycoses, not elsewhere classified	0.003	0.997	0.000
B47 Mycetoma	0.003	0.997	0.000
B46 Zygomycosis	0.003	0.997	0.000
B45 Cryptococcosis	0.003	0.997	0.000
B43 Chromomycosis and phaeomycotic abscess	0.003	0.997	0.000
B42 Sporotrichosis	0.003	0.997	0.000
B41 Paracoccidioidomycosis	0.003	0.997	0.000
B40 Blastomycosis	0.003	0.997	0.000
B39 Histoplasmosis	0.003	0.997	0.000
B38 Coccidioidomycosis	0.003	0.997	0.000
E56.1 Deficiency of vitamin K	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.003	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.003	0.997	0.000
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
E56.9 Vitamin deficiency, unspecified	0.003	0.997	0.000
E56.8 Deficiency of other vitamins	0.003	0.997	0.000
E56.0 Deficiency of vitamin E	0.003	0.997	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.003	0.997	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.003	0.997	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.003	0.997	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.003	0.997	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.003	0.997	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.003	0.997	0.000
S12.11 Fracture of second cervical vertebra (open)	0.003	0.997	0.000
E50.9 Vitamin A deficiency, unspecified	0.003	0.997	0.000
E50.8 Other manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.997	0.000
E50.5 Vitamin A deficiency with night blindness	0.003	0.997	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.997	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.997	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.997	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.997	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.997	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.997	0.000
E63.8 Other specified nutritional deficiencies	0.003	0.997	0.000
E63.1 Imbalance of constituents of food intake	0.003	0.997	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.997	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.997	0.000
E64.8 Sequelae of other nutritional deficiencies	0.003	0.997	0.000
E64.3 Sequelae of rickets	0.003	0.997	0.000
E64.2 Sequelae of vitamin C deficiency	0.003	0.997	0.000
E64.1 Sequelae of vitamin A deficiency	0.003	0.997	0.000
E64.0 Sequelae of protein-energy malnutrition	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.997	0.003
Z75.5 Holiday relief care	0.001	0.997	0.003
E44.1 Mild protein-energy malnutrition	0.003	0.997	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
S48 Traumatic amputation of shoulder and upper arm	0.000	0.997	0.003
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.997	0.003
S44 Injury of nerves at shoulder and upper arm level	0.000	0.997	0.003
S47 Crushing injury of shoulder and upper arm	0.000	0.997	0.003
Z75.8 Other problems related to medical facilities and other health care	0.001	0.997	0.002
Z75.4 Unavailability and inaccessibility of other helping agencies	0.001	0.997	0.002
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.997	0.003
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
S12.81 Fracture of other parts of neck (open)	0.003	0.997	0.000
S12.80 Fracture of other parts of neck (closed)	0.003	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.997	0.003
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.997	0.003
N99-N99 Other disorders of the genitourinary system	0.003	0.997	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.997	0.003
S41 Open wound of shoulder and upper arm	0.000	0.997	0.003
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.997	0.003
S42.11 Fracture of scapula (open)	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.997	0.000
B36 Other superficial mycoses	0.003	0.997	0.000
E55 Vitamin D deficiency	0.002	0.997	0.001
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.003
K41 Femoral hernia	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
S12.01 Fracture of first cervical vertebra (open)	0.002	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.003	0.997	0.000
I49.4 Other and unspecified premature depolarisation	0.003	0.997	0.000
K42.1 Umbilical hernia with gangrene	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.002	0.997	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.997	0.000
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
S12.71 Multiple fractures of cervical spine (open)	0.002	0.997	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.997	0.003
R59.9 Enlarged lymph nodes, unspecified	0.000	0.997	0.003
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.002
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.997	0.002
E21.4 Other specified disorders of parathyroid gland	0.002	0.997	0.000
E21.2 Other hyperparathyroidism	0.002	0.997	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.997	0.000
B38.9 Coccidioidomycosis, unspecified	0.002	0.997	0.000
B38.8 Other forms of coccidioidomycosis	0.002	0.997	0.000
B38.7 Disseminated coccidioidomycosis	0.002	0.997	0.000
B38.4 Coccidioidomycosis meningitis	0.002	0.997	0.000
B38.3 Cutaneous coccidioidomycosis	0.002	0.997	0.000
B38.2 Pulmonary coccidioidomycosis, unspecified	0.002	0.997	0.000
B38.1 Chronic pulmonary coccidioidomycosis	0.002	0.997	0.000
B38.0 Acute pulmonary coccidioidomycosis	0.002	0.997	0.000
B39.9 Histoplasmosis, unspecified	0.002	0.997	0.000
B39.5 Histoplasmosis duboisii	0.002	0.997	0.000
B39.4 Histoplasmosis capsulati, unspecified	0.002	0.997	0.000
B39.3 Disseminated histoplasmosis capsulati	0.002	0.997	0.000
B39.2 Pulmonary histoplasmosis capsulati, unspecified	0.002	0.997	0.000
B39.1 Chronic pulmonary histoplasmosis capsulati	0.002	0.997	0.000
B39.0 Acute pulmonary histoplasmosis capsulati	0.002	0.997	0.000
B40.9 Blastomycosis, unspecified	0.002	0.997	0.000
B40.8 Other forms of blastomycosis	0.002	0.997	0.000
B40.7 Disseminated blastomycosis	0.002	0.997	0.000
B40.3 Cutaneous blastomycosis	0.002	0.997	0.000
B40.2 Pulmonary blastomycosis, unspecified	0.002	0.997	0.000
B40.1 Chronic pulmonary blastomycosis	0.002	0.997	0.000
B40.0 Acute pulmonary blastomycosis	0.002	0.997	0.000
B41.9 Paracoccidioidomycosis, unspecified	0.002	0.997	0.000
B41.8 Other forms of paracoccidioidomycosis	0.002	0.997	0.000
B41.7 Disseminated paracoccidioidomycosis	0.002	0.997	0.000
B41.0 Pulmonary paracoccidioidomycosis	0.002	0.997	0.000
B42.9 Sporotrichosis, unspecified	0.002	0.997	0.000
B42.8 Other forms of sporotrichosis	0.002	0.997	0.000
B42.7 Disseminated sporotrichosis	0.002	0.997	0.000
B42.1 Lymphocutaneous sporotrichosis	0.002	0.997	0.000
B42.0 Pulmonary sporotrichosis	0.002	0.997	0.000
B43.9 Chromomycosis, unspecified	0.002	0.997	0.000
B43.8 Other forms of chromomycosis	0.002	0.997	0.000
B43.2 Subcutaneous phaeomycotic abscess and cyst	0.002	0.997	0.000
B43.1 Phaeomycotic brain abscess	0.002	0.997	0.000
B43.0 Cutaneous chromomycosis	0.002	0.997	0.000
B45.9 Cryptococcosis, unspecified	0.002	0.997	0.000
B45.8 Other forms of cryptococcosis	0.002	0.997	0.000
B45.7 Disseminated cryptococcosis	0.002	0.997	0.000
B45.3 Osseous cryptococcosis	0.002	0.997	0.000
B45.2 Cutaneous cryptococcosis	0.002	0.997	0.000
B45.1 Cerebral cryptococcosis	0.002	0.997	0.000
B45.0 Pulmonary cryptococcosis	0.002	0.997	0.000
B46.9 Zygomycosis, unspecified	0.002	0.997	0.000
B46.8 Other zygomycoses	0.002	0.997	0.000
B46.5 Mucormycosis, unspecified	0.002	0.997	0.000
B46.4 Disseminated mucormycosis	0.002	0.997	0.000
B46.3 Cutaneous mucormycosis	0.002	0.997	0.000
B46.2 Gastro-intestinal mucormycosis	0.002	0.997	0.000
B46.1 Rhinocerebral mucormycosis	0.002	0.997	0.000
B46.0 Pulmonary mucormycosis	0.002	0.997	0.000
B47.9 Mycetoma, unspecified	0.002	0.997	0.000
B47.1 Actinomycetoma	0.002	0.997	0.000
B47.0 Eumycetoma	0.002	0.997	0.000
B48.8 Other specified mycoses	0.002	0.997	0.000
B48.7 Opportunistic mycoses	0.002	0.997	0.000
B48.4 Penicillosis	0.002	0.997	0.000
B48.3 Geotrichosis	0.002	0.997	0.000
B48.2 Allescheriasis	0.002	0.997	0.000
B48.1 Rhinosporidiosis	0.002	0.997	0.000
B48.0 Lobomycosis	0.002	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.997	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.002
T50.5 Appetite depressants	0.000	0.997	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.002
V18.0 Driver injured in nontraffic accident	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.002	0.997	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.002	0.997	0.000
R41.2 Retrograde amnesia	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
M50.2 Other cervical disk displacement	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations