TreeWAS – Variant ID: rs4581716

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H33.0 Retinal detachment with retinal break	0.965	0.035	0.000
H33 Retinal detachments and breaks	0.956	0.044	0.000
H33.2 Serous retinal detachment	0.907	0.093	0.000
H30-H36 Disorders of choroid and retina	0.878	0.122	0.000
Chapter VII Diseases of the eye and adnexa	0.871	0.129	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.861	0.139	0.000
H25-H28 Disorders of lens	0.854	0.146	0.000
H26 Other cataract	0.842	0.158	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.834	0.166	0.000
H20 Iridocyclitis	0.831	0.169	0.000
H52 Disorders of refraction and accommodation	0.822	0.178	0.000
H20.9 Iridocyclitis, unspecified	0.795	0.205	0.000
H52.1 Myopia	0.795	0.205	0.000
H26.4 After-cataract	0.794	0.206	0.000
H33.1 Retinoschisis and retinal cysts	0.784	0.216	0.000
H26.2 Complicated cataract	0.783	0.217	0.000
H33.4 Traction detachment of retina	0.782	0.218	0.000
H18 Other disorders of cornea	0.776	0.224	0.000
H43-H45 Disorders of vitreous body and globe	0.751	0.249	0.000
H20.0 Acute and subacute iridocyclitis	0.749	0.251	0.000
H33.3 Retinal breaks without detachment	0.747	0.253	0.000
H52.2 Astigmatism	0.736	0.264	0.000
H18.6 Keratoconus	0.729	0.271	0.000
H26.0 Infantile, juvenile and presenile cataract	0.714	0.286	0.000
H52.0 Hypermetropia	0.711	0.289	0.000
H10-H13 Disorders of conjunctiva	0.703	0.297	0.000
H44 Disorders of globe	0.702	0.298	0.000
H25 Senile cataract	0.693	0.307	0.000
H44.2 Degenerative myopia	0.689	0.311	0.000
H49 Paralytic strabismus	0.677	0.323	0.000
H16 Keratitis	0.673	0.327	0.000
H25.1 Senile nuclear cataract	0.673	0.327	0.000
H17 Corneal scars and opacities	0.664	0.336	0.000
H21 Other disorders of iris and ciliary body	0.661	0.339	0.000
H26.9 Cataract, unspecified	0.655	0.345	0.000
H26.1 Traumatic cataract	0.651	0.349	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.649	0.351	0.000
H30 Chorioretinal inflammation	0.646	0.354	0.000
H18.4 Corneal degeneration	0.643	0.357	0.000
H18.9 Disorder of cornea, unspecified	0.640	0.360	0.000
H52.7 Disorder of refraction, unspecified	0.636	0.364	0.000
H31 Other disorders of choroid	0.632	0.368	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.630	0.370	0.000
H18.2 Other corneal oedema	0.624	0.376	0.000
H20.1 Chronic iridocyclitis	0.621	0.379	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.610	0.390	0.000
H51 Other disorders of binocular movement	0.600	0.400	0.000
H20.2 Lens-induced iridocyclitis	0.596	0.404	0.000
H52.6 Other disorders of refraction	0.589	0.411	0.000
H52.5 Disorders of accommodation	0.589	0.411	0.000
H52.4 Presbyopia	0.589	0.411	0.000
H16.0 Corneal ulcer	0.588	0.412	0.000
H15 Disorders of sclera	0.587	0.413	0.000
H21.0 Hyphaema	0.586	0.414	0.000
H10 Conjunctivitis	0.582	0.418	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.573	0.427	0.000
H49.0 Third [oculomotor] nerve palsy	0.571	0.429	0.000
H26.3 Drug-induced cataract	0.566	0.434	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.566	0.434	0.000
H18.0 Corneal pigmentations and deposits	0.560	0.439	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.560	0.440	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.558	0.442	0.000
H18.7 Other corneal deformities	0.556	0.444	0.000
H44.1 Other endophthalmitis	0.549	0.451	0.000
H49.2 Sixth [abducent] nerve palsy	0.541	0.459	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.534	0.466	0.000
H33.5 Other retinal detachments	0.532	0.468	0.000
H18.3 Changes in corneal membranes	0.525	0.474	0.000
H17.8 Other corneal scars and opacities	0.522	0.478	0.000
H18.1 Bullous keratopathy	0.519	0.481	0.000
H35 Other retinal disorders	0.517	0.483	0.000
H25.2 Senile cataract, morgagnian type	0.511	0.489	0.000
H44.5 Degenerated conditions of globe	0.504	0.495	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.504	0.496	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.504	0.496	0.000
H44.3 Other degenerative disorders of globe	0.504	0.496	0.000
H28.0 Diabetic cataract	0.502	0.498	0.000
H44.8 Other disorders of globe	0.501	0.499	0.000
H25.8 Other senile cataract	0.498	0.502	0.000
H49.9 Paralytic strabismus, unspecified	0.492	0.508	0.000
H49.8 Other paralytic strabismus	0.486	0.514	0.000
H49.4 Progressive external ophthalmoplegia	0.486	0.514	0.000
H49.3 Total (external) ophthalmoplegia	0.486	0.514	0.000
H16.3 Interstitial and deep keratitis	0.483	0.517	0.000
H27 Other disorders of lens	0.479	0.521	0.000
H13.3 Ocular pemphigoid	0.477	0.523	0.000
H17.1 Other central corneal opacity	0.476	0.524	0.000
H17.0 Adherent leukoma	0.476	0.524	0.000
H17.9 Corneal scar and opacity, unspecified	0.476	0.524	0.000
H16.9 Keratitis, unspecified	0.475	0.525	0.000
H55-H59 Other disorders of eye and adnexa	0.474	0.526	0.000
H30.2 Posterior cyclitis	0.474	0.526	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.474	0.526	0.000
H31.0 Chorioretinal scars	0.474	0.526	0.000
H30.9 Chorioretinal inflammation, unspecified	0.470	0.530	0.000
H31.9 Disorder of choroid, unspecified	0.469	0.531	0.000
H16.8 Other keratitis	0.468	0.532	0.000
H10.9 Conjunctivitis, unspecified	0.467	0.533	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.466	0.534	0.000
H28.2 Cataract in other diseases classified elsewhere	0.466	0.534	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.466	0.534	0.000
H31.1 Choroidal degeneration	0.465	0.535	0.000
H30.8 Other chorioretinal inflammations	0.463	0.536	0.000
H30.1 Disseminated chorioretinal inflammation	0.463	0.536	0.000
H30.0 Focal chorioretinal inflammation	0.463	0.536	0.000
H21.4 Pupillary membranes	0.460	0.540	0.000
H10.4 Chronic conjunctivitis	0.457	0.543	0.000
H31.3 Choroidal haemorrhage and rupture	0.454	0.546	0.000
H31.4 Choroidal detachment	0.453	0.547	0.000
H31.2 Hereditary choroidal dystrophy	0.453	0.547	0.000
H18.8 Other specified disorders of cornea	0.452	0.548	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.451	0.548	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.451	0.548	0.000
H35.5 Hereditary retinal dystrophy	0.451	0.549	0.000
H21.2 Degeneration of iris and ciliary body	0.444	0.555	0.000
H10.1 Acute atopic conjunctivitis	0.443	0.557	0.000
H44.9 Disorder of globe, unspecified	0.439	0.560	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.438	0.562	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.438	0.562	0.000
H15.1 Episcleritis	0.434	0.566	0.000
H36 Retinal disorders in diseases classified elsewhere	0.433	0.567	0.000
H16.4 Corneal neovascularisation	0.433	0.567	0.000
H51.2 Internuclear ophthalmoplegia	0.432	0.568	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.431	0.569	0.000
H51.9 Disorder of binocular movement, unspecified	0.430	0.570	0.000
H51.8 Other specified disorders of binocular movement	0.430	0.570	0.000
H51.1 Convergence insufficiency and excess	0.430	0.570	0.000
H51.0 Palsy of conjugate gaze	0.430	0.570	0.000
H35.6 Retinal haemorrhage	0.425	0.575	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.422	0.577	0.000
H15.8 Other disorders of sclera	0.417	0.583	0.000
H10.8 Other conjunctivitis	0.417	0.583	0.000
H10.5 Blepharoconjunctivitis	0.417	0.583	0.000
H10.2 Other acute conjunctivitis	0.417	0.583	0.000
H10.0 Mucopurulent conjunctivitis	0.417	0.583	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.416	0.584	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.415	0.585	0.000
H15.9 Disorder of sclera, unspecified	0.413	0.587	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.412	0.588	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.411	0.589	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.410	0.589	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.410	0.589	0.000
H13.0 Filarial infection of conjunctiva	0.410	0.589	0.000
H44.0 Purulent endophthalmitis	0.410	0.590	0.000
H35.2 Other proliferative retinopathy	0.410	0.590	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.406	0.594	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.406	0.594	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.403	0.597	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.401	0.598	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.401	0.598	0.000
H11 Other disorders of conjunctiva	0.401	0.599	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.398	0.602	0.000
H31.8 Other specified disorders of choroid	0.394	0.605	0.000
H21.8 Other specified disorders of iris and ciliary body	0.391	0.608	0.000
H15.0 Scleritis	0.390	0.610	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.389	0.611	0.000
H10.3 Acute conjunctivitis, unspecified	0.388	0.611	0.000
H16.2 Keratoconjunctivitis	0.385	0.615	0.000
H49.1 Fourth [trochlear] nerve palsy	0.382	0.618	0.000
H44.4 Hypotony of eye	0.381	0.619	0.000
H35.4 Peripheral retinal degeneration	0.381	0.619	0.000
H20.8 Other iridocyclitis	0.373	0.627	0.000
H35.7 Separation of retinal layers	0.373	0.627	0.000
H35.1 Retinopathy of prematurity	0.370	0.629	0.000
H40-H42 Glaucoma	0.369	0.631	0.000
H27.0 Aphakia	0.362	0.638	0.000
H35.9 Retinal disorder, unspecified	0.360	0.640	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.351	0.648	0.000
H27.8 Other specified disorders of lens	0.347	0.653	0.000
H27.9 Disorder of lens, unspecified	0.344	0.656	0.000
H43 Disorders of vitreous body	0.342	0.658	0.000
H26.8 Other specified cataract	0.337	0.663	0.000
H57 Other disorders of eye and adnexa	0.331	0.669	0.000
H59.0 Vitreous syndrome following cataract surgery	0.329	0.670	0.000
H35.0 Background retinopathy and retinal vascular changes	0.327	0.673	0.000
H11.2 Conjunctival scars	0.314	0.686	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.313	0.687	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.310	0.689	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.310	0.690	0.000
H11.0 Pterygium	0.307	0.693	0.000
H11.3 Conjunctival haemorrhage	0.304	0.696	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.298	0.701	0.000
H46 Optic neuritis	0.296	0.704	0.000
H11.1 Conjunctival degenerations and deposits	0.292	0.708	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.277	0.723	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.273	0.727	0.000
H11.8 Other specified disorders of conjunctiva	0.272	0.728	0.000
H52.3 Anisometropia and aniseikonia	0.269	0.731	0.000
H43.2 Crystalline deposits in vitreous body	0.266	0.734	0.000
H42 Glaucoma in diseases classified elsewhere	0.265	0.735	0.000
H43.1 Vitreous haemorrhage	0.262	0.738	0.000
H11.9 Disorder of conjunctiva, unspecified	0.252	0.748	0.000
H57.0 Anomalies of pupillary function	0.251	0.749	0.000
H43.0 Vitreous prolapse	0.245	0.755	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.223	0.777	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.223	0.777	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.223	0.777	0.000
H43.3 Other vitreous opacities	0.221	0.779	0.000
H35.8 Other specified retinal disorders	0.217	0.783	0.000
H25.0 Senile incipient cataract	0.216	0.784	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.214	0.786	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.214	0.786	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.214	0.786	0.000
H57.1 Ocular pain	0.212	0.788	0.000
H18.5 Hereditary corneal dystrophies	0.203	0.797	0.001
H25.9 Senile cataract, unspecified	0.200	0.800	0.000
H34 Retinal vascular occlusions	0.194	0.804	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.193	0.807	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.190	0.810	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.190	0.810	0.000
H43.9 Disorder of vitreous body, unspecified	0.185	0.814	0.000
H57.8 Other specified disorders of eye and adnexa	0.179	0.821	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.175	0.825	0.000
H53-H54 Visual disturbances and blindness	0.162	0.838	0.000
H27.1 Dislocation of lens	0.160	0.839	0.001
H02 Other disorders of eyelid	0.149	0.851	0.000
H02.9 Disorder of eyelid, unspecified	0.148	0.852	0.000
H34.9 Retinal vascular occlusion, unspecified	0.147	0.852	0.001
H34.0 Transient retinal artery occlusion	0.139	0.860	0.001
H02.3 Blepharochalasis	0.139	0.861	0.000
H34.1 Central retinal artery occlusion	0.124	0.875	0.001
H01 Other inflammation of eyelid	0.123	0.877	0.000
H02.6 Xanthelasma of eyelid	0.123	0.877	0.000
H43.8 Other disorders of vitreous body	0.120	0.880	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.119	0.881	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.118	0.882	0.000
H02.0 Entropion and trichiasis of eyelid	0.117	0.883	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.114	0.885	0.000
H36.0 Diabetic retinopathy	0.114	0.886	0.000
H50 Other strabismus	0.113	0.887	0.000
H01.1 Non-infectious dermatoses of eyelid	0.109	0.891	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.107	0.893	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.097	0.903	0.001
H55 Nystagmus and other irregular eye movements	0.095	0.905	0.001
H01.9 Inflammation of eyelid, unspecified	0.091	0.909	0.000
H50.4 Other and unspecified heterotropia	0.090	0.910	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.085	0.915	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.085	0.915	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.085	0.915	0.000
H00 Hordeolum and chalazion	0.083	0.916	0.001
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.082	0.918	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.082	0.918	0.000
H50.6 Mechanical strabismus	0.081	0.919	0.000
H50.3 Intermittent heterotropia	0.081	0.919	0.000
H50.8 Other specified strabismus	0.081	0.919	0.000
H06.2 Dysthyroid exophthalmos	0.078	0.922	0.000
H02.8 Other specified disorders of eyelid	0.078	0.922	0.000
H01.8 Other specified inflammation of eyelid	0.075	0.925	0.000
H02.2 Lagophthalmos	0.074	0.926	0.000
H50.9 Strabismus, unspecified	0.072	0.928	0.000
H05 Disorders of orbit	0.071	0.928	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.071	0.929	0.000
H47.7 Disorder of visual pathways, unspecified	0.069	0.930	0.001
H47.6 Disorders of visual cortex	0.069	0.930	0.001
H47.5 Disorders of other visual pathways	0.069	0.930	0.001
H47.4 Disorders of optic chiasm	0.069	0.930	0.001
H00.0 Hordeolum and other deep inflammation of eyelid	0.064	0.935	0.000
H47.1 Papilloedema, unspecified	0.060	0.940	0.001
H50.5 Heterophoria	0.059	0.941	0.000
H02.5 Other disorders affecting eyelid function	0.057	0.943	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.051	0.948	0.000
H05.3 Deformity of orbit	0.051	0.948	0.000
H05.1 Chronic inflammatory disorders of orbit	0.051	0.948	0.000
H05.8 Other disorders of orbit	0.051	0.949	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.050	0.950	0.001
H47.3 Other disorders of optic disk	0.050	0.950	0.001
H50.2 Vertical strabismus	0.049	0.951	0.000
H05.0 Acute inflammation of orbit	0.049	0.951	0.000
H01.0 Blepharitis	0.048	0.952	0.000
H05.4 Enophthalmos	0.045	0.955	0.000
H50.0 Convergent concomitant strabismus	0.043	0.957	0.000
H05.9 Disorder of orbit, unspecified	0.042	0.958	0.000
H34.8 Other retinal vascular occlusions	0.040	0.959	0.001
H47.2 Optic atrophy	0.039	0.960	0.001
H34.2 Other retinal artery occlusions	0.036	0.961	0.003
H35.3 Degeneration of macula and posterior pole	0.038	0.962	0.000
H05.2 Exophthalmic conditions	0.037	0.963	0.000
H50.1 Divergent concomitant strabismus	0.034	0.966	0.000
H02.4 Ptosis of eyelid	0.024	0.976	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.977	0.023
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.980	0.020
I62 Other nontraumatic intracranial haemorrhage	0.000	0.981	0.019
H04 Disorders of lachrymal system	0.017	0.983	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.016	0.984	0.000
H04.6 Other changes in lachrymal passages	0.014	0.986	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.986	0.013
H04.0 Dacryoadenitis	0.013	0.987	0.000
H54 Blindness and low vision	0.012	0.988	0.000
H02.1 Ectropion of eyelid	0.011	0.988	0.001
H04.9 Disorder of lachrymal system, unspecified	0.011	0.988	0.000
H54.5 Low vision, one eye	0.010	0.990	0.000
H40 Glaucoma	0.010	0.990	0.000
Z96.1 Presence of intraocular lens	0.009	0.991	0.000
H04.4 Chronic inflammation of lachrymal passages	0.009	0.991	0.000
H54.2 Low vision, both eyes	0.009	0.991	0.000
H54.3 Unqualified visual loss, both eyes	0.009	0.991	0.000
H04.8 Other disorders of lachrymal system	0.009	0.991	0.000
H54.6 Unqualified visual loss, one eye	0.008	0.992	0.000
H40.3 Glaucoma secondary to eye trauma	0.008	0.992	0.000
H40.6 Glaucoma secondary to drugs	0.008	0.992	0.000
H54.1 Blindness, one eye, low vision, other eye	0.008	0.992	0.000
H40.8 Other glaucoma	0.007	0.993	0.000
H40.4 Glaucoma secondary to eye inflammation	0.007	0.993	0.000
H53 Visual disturbances	0.007	0.993	0.000
T51.0 Ethanol	0.007	0.993	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.994	0.006
K61.0 Anal abscess	0.000	0.994	0.006
S64.4 Injury of digital nerve of other finger	0.000	0.994	0.006
O80.9 Single spontaneous delivery, unspecified	0.006	0.994	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.006	0.994	0.000
H53.3 Other disorders of binocular vision	0.005	0.995	0.000
R82.9 Other and unspecified abnormal finding in urine	0.005	0.995	0.000
H04.2 Epiphora	0.005	0.995	0.000
H53.6 Night blindness	0.005	0.995	0.000
H53.5 Colour vision deficiencies	0.005	0.995	0.000
H54.9 Unspecified visual impairment (binocular)	0.005	0.995	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.995	0.005
R82 Other abnormal findings in urine	0.005	0.995	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.005	0.995	0.000
L60.8 Other nail disorders	0.005	0.995	0.000
R94.3 Abnormal results of cardiovascular function studies	0.005	0.995	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.005	0.995	0.000
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
R82.4 Acetonuria	0.004	0.996	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
S31.1 Open wound of abdominal wall	0.004	0.996	0.000
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
S31 Open wound of abdomen, lower back and pelvis	0.004	0.996	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.004	0.996	0.000
N60.3 Fibrosclerosis of breast	0.000	0.996	0.004
H54.0 Blindness, both eyes	0.004	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
H54.7 Unspecified visual loss	0.004	0.996	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
R82.3 Haemoglobinuria	0.004	0.996	0.000
R82.2 Biliuria	0.004	0.996	0.000
R82.0 Chyluria	0.004	0.996	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.996	0.004
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.004	0.996	0.000
H53.4 Visual field defects	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
S31.2 Open wound of penis	0.004	0.996	0.000
S31.3 Open wound of scrotum and testes	0.004	0.996	0.000
L60.3 Nail dystrophy	0.004	0.996	0.000
H40.5 Glaucoma secondary to other eye disorders	0.003	0.996	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.996	0.000
Z50.8 Care involving use of rehabilitation procedures	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.003	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.003	0.997	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.003	0.997	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.003	0.997	0.000
R82.1 Myoglobinuria	0.003	0.997	0.000
Z87.8 Personal history of other specified conditions	0.003	0.997	0.000
L60 Nail disorders	0.003	0.997	0.000
H00.1 Chalazion	0.001	0.997	0.002
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.997	0.003
L60.2 Onychogryphosis	0.003	0.997	0.000
R81 Glycosuria	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
S31.4 Open wound of vagina and vulva	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
M93 Other osteochondropathies	0.000	0.997	0.003
H40.9 Glaucoma, unspecified	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
R32 Unspecified urinary incontinence	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
K26.5 Chronic or unspecified with perforation	0.000	0.997	0.003
R80 Isolated proteinuria	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.003	0.997	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.002	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
S32.3 Fracture of ilium	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.002	0.997	0.000
L60.4 Beau's lines	0.002	0.997	0.000
L60.1 Onycholysis	0.002	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.002	0.997	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.997	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
M21 Other acquired deformities of limbs	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.998	0.002
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.998	0.002
M93.1 Kienbock's disease of adults	0.000	0.998	0.002
M21.2 Flexion deformity	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
M93.8 Other specified osteochondropathies	0.000	0.998	0.002
M93.2 Osteochondritis dissecans	0.000	0.998	0.002
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.000	0.998	0.002
I12 Hypertensive renal disease	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.001	0.998	0.001
S33.5 Sprain and strain of lumbar spine	0.002	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
T51.8 Other alcohols	0.002	0.998	0.000
T51.3 Fusel oil	0.002	0.998	0.000
T51.2 2-Propanol	0.002	0.998	0.000
T51.1 Methanol	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.002	0.998	0.000
W49.9 Unspecified place	0.002	0.998	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
H53.8 Other visual disturbances	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.002	0.998	0.000
K61 Abscess of anal and rectal regions	0.000	0.998	0.002
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.5 Injury of iliac blood vessels	0.002	0.998	0.000
S35.4 Injury of renal blood vessels	0.002	0.998	0.000
S35.3 Injury of portal or splenic vein	0.002	0.998	0.000
S35.1 Injury of inferior vena cava	0.002	0.998	0.000
S35.0 Injury of abdominal aorta	0.002	0.998	0.000
H40.1 Primary open-angle glaucoma	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.0 Crushing injury of external genital organs	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
M93.26 Osteochondritis dissecans knee	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations