TreeWAS – Variant ID: rs4591494

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.041	0.959	0.000
I60 Subarachnoid haemorrhage	0.040	0.960	0.000
I60.8 Other subarachnoid haemorrhage	0.039	0.961	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.036	0.964	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.033	0.967	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.033	0.967	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.032	0.968	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.029	0.970	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.029	0.970	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.029	0.971	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.019	0.981	0.000
K08.3 Retained dental root	0.000	0.983	0.017
H11.4 Other conjunctival vascular disorders and cysts	0.013	0.987	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.991	0.009
M25.51 Pain in joint (Shoulder region)	0.000	0.992	0.008
K01.1 Impacted teeth	0.008	0.992	0.000
R87.6 Abnormal cytological findings	0.006	0.994	0.000
Y45.1 Salicylates	0.000	0.994	0.006
H11 Other disorders of conjunctiva	0.006	0.994	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.995	0.005
K01 Embedded and impacted teeth	0.005	0.995	0.000
H11.9 Disorder of conjunctiva, unspecified	0.005	0.995	0.000
K01.0 Embedded teeth	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
H11.3 Conjunctival haemorrhage	0.004	0.995	0.000
H11.2 Conjunctival scars	0.004	0.996	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.996	0.004
H11.0 Pterygium	0.004	0.996	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.996	0.004
J43.9 Emphysema, unspecified	0.000	0.996	0.004
I27.0 Primary pulmonary hypertension	0.000	0.996	0.004
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.000	0.996	0.004
O36.5 Maternal care for poor foetal growth	0.004	0.996	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.996	0.004
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.996	0.004
R87 Abnormal findings in specimens from female genital organs	0.003	0.996	0.000
N80.3 Endometriosis of pelvic peritoneum	0.003	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.003	0.997	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.997	0.003
Z22.3 Carrier of other specified bacterial diseases	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.997	0.003
L98.4 Chronic ulcer of skin, not elsewhere classified	0.000	0.997	0.003
R22.2 Localised swelling, mass and lump, trunk	0.000	0.997	0.003
R87.9 Unspecified abnormal finding	0.003	0.997	0.000
M65.34 Trigger finger-Hand	0.000	0.997	0.003
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Y45.5 4-Aminophenol derivatives	0.000	0.997	0.003
H11.1 Conjunctival degenerations and deposits	0.003	0.997	0.000
L98.5 Mucinosis of skin	0.000	0.997	0.003
Z37.2 Twins, both liveborn	0.003	0.997	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.000	0.997	0.003
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.000	0.997	0.003
L98.3 Eosinophilic cellulitis [Wells]	0.000	0.997	0.003
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
M70.46 Prepatellar bursitis-Lower Leg	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
Y45.4 Antirheumatics	0.000	0.997	0.003
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.997	0.003
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
R23.3 Spontaneous ecchymoses	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
R87.8 Other abnormal findings	0.003	0.997	0.000
R87.5 Abnormal microbiological findings	0.003	0.997	0.000
R87.4 Abnormal immunological findings	0.003	0.997	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R87.1 Abnormal level of hormones	0.003	0.997	0.000
R87.0 Abnormal level of enzymes	0.003	0.997	0.000
S01.2 Open wound of nose	0.000	0.997	0.003
L98.0 Pyogenic granuloma	0.000	0.997	0.003
H81.3 Other peripheral vertigo	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.997	0.002
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
K22.8 Other specified diseases of oesophagus	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
L98.1 Factitial dermatitis	0.000	0.997	0.002
X50.4 Street and highway	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
O30.0 Twin pregnancy	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.997	0.002
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.998	0.002
R87.7 Abnormal histological findings	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
J43 Emphysema	0.000	0.998	0.002
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
S01 Open wound of head	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
J43.2 Centrilobular emphysema	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.000	0.998	0.002
R01.0 Benign and innocent cardiac murmurs	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
Z74.0 Reduced mobility	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
H10-H13 Disorders of conjunctiva	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
K51.8 Other ulcerative colitis	0.000	0.998	0.002
Y40.4 Tetracyclines	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.000	0.998	0.002
J43.0 MacLeod's syndrome	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
S01.8 Open wound of other parts of head	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.998	0.002
X50 Overexertion and strenuous or repetitive movements	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
J43.8 Other emphysema	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
S91.0 Open wound of ankle	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.998	0.002
M62 Other disorders of muscle	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
G47.3 Sleep apnoea	0.002	0.998	0.000
M70.4 Prepatellar bursitis	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.998	0.002
L71.1 Rhinophyma	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.001
M62.6 Muscle strain	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
R04.2 Haemoptysis	0.000	0.998	0.002
X50.2 School, other institution and public administrative area	0.002	0.998	0.000
Z22 Carrier of infectious disease	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
S01.7 Multiple open wounds of head	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
M65.3 Trigger finger	0.000	0.998	0.002
M66.2 Spontaneous rupture of extensor tendons	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
S91 Open wound of ankle and foot	0.000	0.998	0.002
R23.1 Pallor	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.002
X50.9 Unspecified place	0.001	0.998	0.000
X50.8 Other specified place	0.001	0.998	0.000
X50.5 Trade and service area	0.001	0.998	0.000
X50.3 Sports and athletics area	0.001	0.998	0.000
X50.0 Home	0.001	0.998	0.000
X50.7 Farm	0.001	0.998	0.000
X50.1 Residential institution	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.002	0.998	0.000
X50.6 Industrial and construction area	0.001	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.000	0.998	0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
M62.9 Disorder of muscle, unspecified	0.001	0.998	0.000
M62.4 Contracture of muscle	0.001	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.998	0.000
M62.0 Diastasis of muscle	0.001	0.998	0.000
Y41.5 Antiviral drugs	0.001	0.998	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.001	0.998	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.001	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.998	0.000
M70.49 Prepatellar bursitis-Site unspec	0.001	0.998	0.000
M70.48 Prepatellar bursitis-Other	0.001	0.998	0.000
M70.47 Prepatellar bursitis-Ankle/Foot	0.001	0.998	0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.001	0.998	0.000
M70.44 Prepatellar bursitis-Hand	0.001	0.998	0.000
M70.43 Prepatellar bursitis-Forearm	0.001	0.998	0.000
M70.42 Prepatellar bursitis-Upper arm	0.001	0.998	0.000
M70.41 Prepatellar bursitis-Shldr region	0.001	0.998	0.000
M70.40 Prepatellar bursitis-Mult sites	0.001	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
G51.3 Clonic hemifacial spasm	0.002	0.998	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.001	0.998	0.000
H13.3 Ocular pemphigoid	0.001	0.998	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.001	0.998	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
H13.0 Filarial infection of conjunctiva	0.001	0.998	0.000
R85.7 Abnormal histological findings	0.001	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.0 Sulphonamides	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.001	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.001	0.998	0.000
E07.8 Other specified disorders of thyroid	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.001
B02.2 Zoster with other nervous system involvement	0.001	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.001	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.001	0.998	0.000
G47 Sleep disorders	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
C09.9 Tonsil, unspecified	0.001	0.999	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.999	0.001
S06.2 Diffuse brain injury	0.000	0.999	0.001
X69.9 Unspecified place	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
Z22.9 Carrier of infectious disease, unspecified	0.001	0.999	0.000
Z22.8 Carrier of other infectious diseases	0.001	0.999	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.001	0.999	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
Z22.2 Carrier of diphtheria	0.001	0.999	0.000
Z22.0 Carrier of typhoid	0.001	0.999	0.000
H10 Conjunctivitis	0.001	0.999	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.999	0.001
R83 Abnormal findings in cerebrospinal fluid	0.001	0.999	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.999	0.001
X59.3 Sports and athletics area	0.001	0.999	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.001	0.999	0.000
M65.39 Trigger finger-Site unspec	0.000	0.999	0.001
M65.38 Trigger finger-Other	0.000	0.999	0.001
M65.37 Trigger finger-Ankle/foot	0.000	0.999	0.001
M65.36 Trigger finger-Lower leg	0.000	0.999	0.001
M65.35 Trigger finger-Pelvic/thigh	0.000	0.999	0.001
M65.33 Trigger finger-Forearm	0.000	0.999	0.001
M65.32 Trigger finger-Upper arm	0.000	0.999	0.001
M65.31 Trigger finger-Shldr region	0.000	0.999	0.001
M65.30 Trigger finger-Mult sites	0.000	0.999	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.000	0.999	0.001
M66.28 Spontaneous rupture of extensor tendons-Other	0.000	0.999	0.001
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.000	0.999	0.001
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.000	0.999	0.001
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.000	0.999	0.001
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.000	0.999	0.001
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.000	0.999	0.001
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.000	0.999	0.001
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.000	0.999	0.001
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
S01.9 Open wound of head, part unspecified	0.000	0.999	0.001
S91.7 Multiple open wounds of ankle and foot	0.000	0.999	0.001
S91.2 Open wound of toe(s) with damage to nail	0.000	0.999	0.001
V09.0 Pedestrian injured in nontraffic accident involving other and unspecified motor vehicles	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
Z98.0 Intestinal bypass and anastomosis status	0.001	0.999	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.001	0.999	0.000
X50.09 Overexertion and strenuous or repetitive movements; Home; During unspecified activity	0.001	0.999	0.000
X50.04 Overexertion and strenuous or repetitive movements; Home; While resting, sleeping, eating or engaging in other vital activities	0.001	0.999	0.000
X50.30 Overexertion and strenuous or repetitive movements; Sports and athletics area;While engaged in sports activity	0.001	0.999	0.000
X50.52 Overexertion and strenuous or repetitive movements, Trade and service area, While working for income	0.001	0.999	0.000
X50.89 Overexertion and strenuous or repetitive movements: Other specified places: During unspecified activity	0.001	0.999	0.000
X50.82 Overexertion and strenuous or repetitive movements; Other specified places ;While working for income	0.001	0.999	0.000
X50.99 Overexertion and strenuous or repetitive movements; Unspecified place ;During unspecified activity	0.001	0.999	0.000
X50.90 Overexertion and strenuous or repetitive movements: Unspecified place: While engaged in sports activity	0.001	0.999	0.000
B35.3 Tinea pedis	0.000	0.999	0.001
G47.9 Sleep disorder, unspecified	0.001	0.999	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.999	0.001
I89.0 Lymphoedema, not elsewhere classified	0.001	0.999	0.000
L71.8 Other rosacea	0.000	0.999	0.001
L71.0 Perioral dermatitis	0.000	0.999	0.001
R84.5 Abnormal microbiological findings	0.001	0.999	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.999	0.001
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.999	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.999	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.999	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.001	0.999	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.999	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.999	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.999	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.999	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.999	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.999	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.999	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.999	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.999	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.999	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.999	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.999	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.999	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.999	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.999	0.000
M62.48 Contracture of muscle (Other)	0.001	0.999	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations