TreeWAS – Variant ID: rs4657015

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Q61.3 Polycystic kidney, unspecified	0.000	0.819	0.181
Q61 Cystic kidney disease	0.000	0.843	0.157
Q61.2 Polycystic kidney, adult type	0.000	0.848	0.152
Q61.5 Medullary cystic kidney	0.000	0.878	0.122
Q61.4 Renal dysplasia	0.000	0.886	0.114
Q61.8 Other cystic kidney diseases	0.000	0.887	0.113
Q61.1 Polycystic kidney, infantile type	0.000	0.887	0.113
Q61.9 Cystic kidney disease, unspecified	0.000	0.897	0.102
Q61.0 Congenital single renal cyst	0.000	0.905	0.095
Q60-Q64 Congenital malformations of the urinary system	0.000	0.941	0.059
Q64 Other congenital malformations of urinary system	0.000	0.953	0.047
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.954	0.046
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.957	0.042
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.959	0.041
Q60.2 Renal agenesis, unspecified	0.000	0.964	0.036
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.966	0.034
Q64.8 Other specified congenital malformations of urinary system	0.000	0.966	0.034
Q64.6 Congenital diverticulum of bladder	0.000	0.966	0.034
Q64.5 Congenital absence of bladder and urethra	0.000	0.966	0.034
Q64.2 Congenital posterior urethral valves	0.000	0.966	0.034
Q64.1 Exstrophy of urinary bladder	0.000	0.966	0.034
Q64.0 Epispadias	0.000	0.966	0.034
Q60.0 Renal agenesis, unilateral	0.000	0.966	0.033
Q60.6 Potter's syndrome	0.000	0.967	0.033
Q60.5 Renal hypoplasia, unspecified	0.000	0.967	0.033
Q60.4 Renal hypoplasia, bilateral	0.000	0.967	0.033
Q60.3 Renal hypoplasia, unilateral	0.000	0.967	0.033
Q60.1 Renal agenesis, bilateral	0.000	0.967	0.033
Q62.2 Congenital megaloureter	0.000	0.967	0.033
Q62.5 Duplication of ureter	0.000	0.967	0.033
Q64.4 Malformation of urachus	0.000	0.968	0.032
Q62.8 Other congenital malformations of ureter	0.000	0.969	0.031
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.969	0.031
Q62.6 Malposition of ureter	0.000	0.969	0.031
Q62.4 Agenesis of ureter	0.000	0.969	0.031
Q62.0 Congenital hydronephrosis	0.000	0.969	0.031
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.970	0.030
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.971	0.029
Q62.1 Atresia and stenosis of ureter	0.000	0.973	0.027
Q63 Other congenital malformations of kidney	0.000	0.977	0.023
Q63.3 Hyperplastic and giant kidney	0.000	0.983	0.017
C71.1 Frontal lobe	0.016	0.984	0.000
Q63.8 Other specified congenital malformations of kidney	0.000	0.984	0.016
C71 Malignant neoplasm of brain	0.016	0.984	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.984	0.016
C71.9 Brain, unspecified	0.016	0.984	0.000
C71.2 Temporal lobe	0.016	0.984	0.000
Q63.2 Ectopic kidney	0.000	0.985	0.015
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.986	0.013
C71.8 Overlapping lesion of brain	0.012	0.988	0.000
Q63.0 Accessory kidney	0.000	0.988	0.012
C71.5 Cerebral ventricle	0.012	0.988	0.000
C71.7 Brain stem	0.012	0.988	0.000
C71.6 Cerebellum	0.011	0.988	0.000
C71.3 Parietal lobe	0.011	0.989	0.000
C71.0 Cerebrum, except lobes and ventricles	0.011	0.989	0.000
C71.4 Occipital lobe	0.010	0.990	0.000
K65.0 Acute peritonitis	0.000	0.991	0.009
K65 Peritonitis	0.000	0.991	0.009
K65.8 Other peritonitis	0.000	0.991	0.009
K65.9 Peritonitis, unspecified	0.000	0.991	0.009
T90.2 Sequelae of fracture of skull and facial bones	0.007	0.993	0.000
M19.98 Arthrosis, unspecified (Other)	0.007	0.993	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.007	0.993	0.000
L85.9 Epidermal thickening, unspecified	0.007	0.993	0.000
T90 Sequelae of injuries of head	0.006	0.994	0.000
T90.9 Sequelae of unspecified injury of head	0.006	0.994	0.000
T90.5 Sequelae of intracranial injury	0.006	0.994	0.000
H00.1 Chalazion	0.005	0.995	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.005	0.995	0.000
T90.0 Sequelae of superficial injury of head	0.005	0.995	0.000
T90.3 Sequelae of injury of cranial nerves	0.005	0.995	0.000
T90.8 Sequelae of other specified injuries of head	0.005	0.995	0.000
T90.1 Sequelae of open wound of head	0.005	0.995	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.995	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
H83.0 Labyrinthitis	0.000	0.996	0.004
I69 Sequelae of cerebrovascular disease	0.000	0.996	0.004
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.004	0.996	0.000
C69 Malignant neoplasm of eye and adnexa	0.004	0.996	0.000
Z90.3 Acquired absence of part of stomach	0.000	0.996	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.996	0.004
Q53.1 Undescended testicle, unilateral	0.000	0.996	0.004
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.000	0.996	0.004
Q54.0 Hypospadias, balanic	0.000	0.996	0.004
Q54 Hypospadias	0.000	0.996	0.004
Q53 Undescended testicle	0.000	0.996	0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.996	0.004
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
C70 Malignant neoplasm of meninges	0.003	0.996	0.000
C69.6 Orbit	0.004	0.996	0.000
C69.0 Conjunctiva	0.004	0.996	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
C50.3 Lower-inner quadrant of breast	0.004	0.996	0.000
K22.8 Other specified diseases of oesophagus	0.000	0.996	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.003	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.003	0.997	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
C69.2 Retina	0.003	0.997	0.000
E87.7 Fluid overload	0.000	0.997	0.003
Q51 Congenital malformations of uterus and cervix	0.000	0.997	0.003
Q65 Congenital deformities of hip	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.997	0.003
C69.8 Overlapping lesion of eye and adnexa	0.003	0.997	0.000
C69.5 Lachrymal gland and duct	0.003	0.997	0.000
C69.1 Cornea	0.003	0.997	0.000
C72.9 Central nervous system, unspecified	0.003	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.003	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.003	0.997	0.000
C72.4 Acoustic nerve	0.003	0.997	0.000
C72.3 Optic nerve	0.003	0.997	0.000
C72.2 Olfactory nerve	0.003	0.997	0.000
C72.1 Cauda equina	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
Z42 Follow-up care involving plastic surgery	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.997	0.003
C69.4 Ciliary body	0.003	0.997	0.000
C72.0 Spinal cord	0.003	0.997	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.003	0.997	0.000
Q54.8 Other hypospadias	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
K27 Peptic ulcer, site unspecified	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.997	0.003
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.997	0.003
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
C69.9 Eye, unspecified	0.003	0.997	0.000
Q54.4 Congenital chordee	0.000	0.997	0.003
Q54.3 Hypospadias, perineal	0.000	0.997	0.003
Q54.2 Hypospadias, penoscrotal	0.000	0.997	0.003
Q54.1 Hypospadias, penile	0.000	0.997	0.003
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.000	0.997	0.003
Q53.0 Ectopic testis	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
C70.9 Meninges, unspecified	0.003	0.997	0.000
C70.1 Spinal meninges	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.000	0.997	0.003
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
T23.2 Burn of second degree of wrist and hand	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.000	0.997	0.002
Q54.9 Hypospadias, unspecified	0.000	0.997	0.003
Q78 Other osteochondrodysplasias	0.002	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
K26.0 Acute with haemorrhage	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.997	0.003
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.997	0.003
Q51.6 Embryonic cyst of cervix	0.000	0.997	0.003
Q51.5 Agenesis and aplasia of cervix	0.000	0.997	0.003
Q51.0 Agenesis and aplasia of uterus	0.000	0.997	0.003
Q65.6 Unstable hip	0.002	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
K27.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.997	0.003
Q52.5 Fusion of labia	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.997	0.003
Q70 Syndactyly	0.002	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.000	0.997	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.997	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.997	0.002
Q68 Other congenital musculoskeletal deformities	0.002	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.997	0.002
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
Q75 Other congenital malformations of skull and face bones	0.002	0.997	0.000
Q73 Reduction defects of unspecified limb	0.002	0.997	0.000
Q72 Reduction defects of lower limb	0.002	0.997	0.000
Q71 Reduction defects of upper limb	0.002	0.997	0.000
Q69 Polydactyly	0.002	0.997	0.000
K65-K67 Diseases of peritoneum	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.002	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.997	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.997	0.002
Q76.0 Spina bifida occulta	0.002	0.997	0.000
T23.3 Burn of third degree of wrist and hand	0.002	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.997	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.997	0.000
K27.5 Chronic or unspecified with perforation	0.002	0.997	0.000
K27.2 Acute with both haemorrhage and perforation	0.002	0.997	0.000
K27.1 Acute with perforation	0.002	0.997	0.000
K27.0 Acute with haemorrhage	0.002	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.000	0.997	0.002
T36.8 Other systemic antibiotics	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.000	0.998	0.002
Q76.5 Cervical rib	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.002
K27.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
K27.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.998	0.002
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.998	0.002
Q52.7 Other congenital malformations of vulva	0.000	0.998	0.002
Q52.6 Congenital malformation of clitoris	0.000	0.998	0.002
Q52.3 Imperforate hymen	0.000	0.998	0.002
Q52.2 Congenital rectovaginal fistula	0.000	0.998	0.002
Q52.0 Congenital absence of vagina	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.000	0.998	0.002
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.998	0.002
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.002
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.002
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.998	0.002
Q40.2 Other specified congenital malformations of stomach	0.000	0.998	0.002
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q05 Spina bifida	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
L85 Other epidermal thickening	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.001
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.000	0.998	0.002
Q52.4 Other congenital malformations of vagina	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
X58.9 Unspecified place	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
T45.5 Anticoagulants	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
Q78.2 Osteopetrosis	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.000	0.998	0.002
T36.4 Tetracyclines	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
Q90 Down's syndrome	0.000	0.998	0.002
Q52.1 Doubling of vagina	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
N81.8 Other female genital prolapse	0.000	0.998	0.002
Q70.3 Webbed toes	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.002	0.998	0.000
T23.6 Corrosion of second degree of wrist and hand	0.002	0.998	0.000
T23.5 Corrosion of first degree of wrist and hand	0.002	0.998	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
Q35 Cleft palate	0.000	0.998	0.002
Q40 Other congenital malformations of upper alimentary tract	0.000	0.998	0.002
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
G44.8 Other specified headache syndromes	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
H83 Other diseases of inner ear	0.000	0.998	0.002
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.000	0.998	0.002
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.998	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.998	0.002
Q50.3 Other congenital malformations of ovary	0.000	0.998	0.002
Q50.2 Congenital torsion of ovary	0.000	0.998	0.002
Q50.1 Developmental ovarian cyst	0.000	0.998	0.002
Q50.0 Congenital absence of ovary	0.000	0.998	0.002
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
Q36 Cleft lip	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.998	0.002
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.998	0.002
Q55.5 Congenital absence and aplasia of penis	0.000	0.998	0.002
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.000	0.998	0.002
Q55.3 Atresia of vas deferens	0.000	0.998	0.002
Q55.1 Hypoplasia of testis and scrotum	0.000	0.998	0.002
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.000	0.998	0.002
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.000	0.998	0.002
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.000	0.998	0.002
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.000	0.998	0.002
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.000	0.998	0.002
Q91 Edwards' syndrome and Patau's syndrome	0.000	0.998	0.002
J38.4 Oedema of larynx	0.000	0.998	0.002
N32.0 Bladder-neck obstruction	0.000	0.998	0.002
R45.1 Restlessness and agitation	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.002	0.998	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.998	0.002
Q37 Cleft palate with cleft lip	0.000	0.998	0.002
J30.1 Allergic rhinitis due to pollen	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
T25.3 Burn of third degree of ankle and foot	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations