TreeWAS – Variant ID: rs4694744

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C50.4 Upper-outer quadrant of breast	0.088	0.912	0.000
D70 Agranulocytosis	0.058	0.942	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.048	0.952	0.000
D73 Diseases of spleen	0.047	0.952	0.000
H18.5 Hereditary corneal dystrophies	0.045	0.955	0.000
D73.0 Hyposplenism	0.045	0.955	0.000
D73.5 Infarction of spleen	0.040	0.960	0.000
H18 Other disorders of cornea	0.040	0.960	0.000
D72 Other disorders of white blood cells	0.039	0.961	0.000
H18.4 Corneal degeneration	0.038	0.962	0.000
D73.3 Abscess of spleen	0.038	0.962	0.000
D73.9 Disease of spleen, unspecified	0.037	0.963	0.000
D73.1 Hypersplenism	0.035	0.965	0.000
D74 Methaemoglobinaemia	0.034	0.966	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.034	0.966	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.034	0.966	0.000
D73.2 Chronic congestive splenomegaly	0.034	0.966	0.000
D73.8 Other diseases of spleen	0.033	0.967	0.000
D73.4 Cyst of spleen	0.033	0.967	0.000
H18.2 Other corneal oedema	0.033	0.967	0.000
D72.8 Other specified disorders of white blood cells	0.033	0.967	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.032	0.968	0.000
H18.8 Other specified disorders of cornea	0.032	0.968	0.000
H18.1 Bullous keratopathy	0.031	0.969	0.000
D72.1 Eosinophilia	0.030	0.970	0.000
H18.7 Other corneal deformities	0.029	0.971	0.000
H18.3 Changes in corneal membranes	0.029	0.971	0.000
D72.9 Disorder of white blood cells, unspecified	0.028	0.971	0.000
D72.0 Genetic anomalies of leukocytes	0.028	0.971	0.000
H18.0 Corneal pigmentations and deposits	0.028	0.971	0.000
H18.6 Keratoconus	0.025	0.974	0.000
H18.9 Disorder of cornea, unspecified	0.025	0.975	0.000
D74.9 Methaemoglobinaemia, unspecified	0.025	0.975	0.000
D74.8 Other methaemoglobinaemias	0.025	0.975	0.000
D74.0 Congenital methaemoglobinaemia	0.025	0.975	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.023	0.977	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.023	0.977	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.023	0.977	0.000
D76.3 Other histiocytosis syndromes	0.021	0.979	0.000
D75 Other diseases of blood and blood-forming organs	0.021	0.979	0.000
D75.2 Essential thrombocytosis	0.016	0.984	0.000
D75.0 Familial erythrocytosis	0.015	0.985	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.013	0.987	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.013	0.987	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.010	0.990	0.000
D75.1 Secondary polycythaemia	0.010	0.990	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.990	0.010
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.009	0.991	0.000
H21 Other disorders of iris and ciliary body	0.009	0.991	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.992	0.008
O70.1 Second degree perineal laceration during delivery	0.008	0.992	0.000
S06.2 Diffuse brain injury	0.000	0.992	0.008
H21.5 Other adhesions and disruptions of iris and ciliary body	0.008	0.992	0.000
H15 Disorders of sclera	0.008	0.992	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.008	0.992	0.000
H16 Keratitis	0.008	0.992	0.000
S06 Intracranial injury	0.000	0.992	0.008
H21.4 Pupillary membranes	0.007	0.993	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.993	0.007
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.993	0.007
H16.9 Keratitis, unspecified	0.007	0.993	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.007	0.993	0.000
S06.9 Intracranial injury, unspecified	0.000	0.993	0.007
H21.2 Degeneration of iris and ciliary body	0.007	0.993	0.000
S06.4 Epidural haemorrhage	0.000	0.993	0.007
H17 Corneal scars and opacities	0.006	0.994	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.006	0.994	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.006	0.994	0.000
H16.2 Keratoconjunctivitis	0.006	0.994	0.000
H15.9 Disorder of sclera, unspecified	0.006	0.994	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.994	0.006
S06.8 Other intracranial injuries	0.000	0.994	0.006
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
N36.8 Other specified disorders of urethra	0.006	0.994	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.994	0.006
T91.3 Sequelae of injury of spinal cord	0.000	0.994	0.006
H21.1 Other vascular disorders of iris and ciliary body	0.006	0.994	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.994	0.006
H21.0 Hyphaema	0.006	0.994	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.994	0.006
H15.0 Scleritis	0.006	0.994	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.006	0.994	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.006	0.994	0.000
H16.4 Corneal neovascularisation	0.006	0.994	0.000
H15.8 Other disorders of sclera	0.006	0.994	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.006	0.994	0.000
C44.5 Skin of trunk	0.006	0.994	0.000
H16.8 Other keratitis	0.006	0.994	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.006	0.994	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.994	0.006
S06.1 Traumatic cerebral oedema	0.000	0.994	0.006
H15.1 Episcleritis	0.005	0.994	0.000
H16.3 Interstitial and deep keratitis	0.005	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.994	0.005
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.995	0.005
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.995	0.005
S06.0 Concussion	0.000	0.995	0.005
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.005	0.995	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.005	0.995	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.005	0.995	0.000
C50 Malignant neoplasm of breast	0.005	0.995	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.995	0.005
H16.1 Other superficial keratitis without conjunctivitis	0.005	0.995	0.000
S06.3 Focal brain injury	0.000	0.995	0.005
J98.9 Respiratory disorder, unspecified	0.005	0.995	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.995	0.005
M72.2 Plantar fascial fibromatosis	0.005	0.995	0.000
C92.1 Chronic myeloid leukaemia	0.005	0.995	0.000
H17.1 Other central corneal opacity	0.005	0.995	0.000
H17.0 Adherent leukoma	0.005	0.995	0.000
H21.8 Other specified disorders of iris and ciliary body	0.005	0.995	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.995	0.005
T91 Sequelae of injuries of neck and trunk	0.000	0.995	0.005
H17.8 Other corneal scars and opacities	0.004	0.995	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.995	0.005
H22.1 Iridocyclitis in other diseases classified elsewhere	0.004	0.995	0.000
T91.1 Sequelae of fracture of spine	0.000	0.995	0.005
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.996	0.004
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.996	0.004
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.996	0.004
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.996	0.004
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.996	0.004
J98.1 Pulmonary collapse	0.004	0.996	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.996	0.004
S72.10 Pertrochanteric fracture (closed)	0.004	0.996	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.996	0.004
H16.0 Corneal ulcer	0.004	0.996	0.000
H17.9 Corneal scar and opacity, unspecified	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.004	0.996	0.000
M72.29 Plantar fascial fibromatosis-Site unspec	0.004	0.996	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
C50.8 Overlapping lesion of breast	0.004	0.996	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.996	0.004
J98 Other respiratory disorders	0.004	0.996	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.996	0.004
S06.00 Concussion (without open intracranial wound)	0.000	0.996	0.004
J98.8 Other specified respiratory disorders	0.004	0.996	0.000
C50.0 Nipple and areola	0.004	0.996	0.000
M72.28 Plantar fascial fibromatosis-Other	0.004	0.996	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.004	0.996	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.004	0.996	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.004	0.996	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.004	0.996	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.004	0.996	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.004	0.996	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.004	0.996	0.000
C50.1 Central portion of breast	0.004	0.996	0.000
C50.6 Axillary tail of breast	0.004	0.996	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.996	0.004
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.996	0.004
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.996	0.004
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
J98.6 Disorders of diaphragm	0.004	0.996	0.000
C92 Myeloid leukaemia	0.004	0.996	0.000
S81.0 Open wound of knee	0.000	0.996	0.004
H20 Iridocyclitis	0.002	0.997	0.001
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.997	0.003
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.997	0.003
R26.8 Other and unspecified abnormalities of gait and mobility	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
J98.3 Compensatory emphysema	0.003	0.997	0.000
J98.2 Interstitial emphysema	0.003	0.997	0.000
G82.5 Tetraplegia, unspecified	0.000	0.997	0.003
C92.9 Myeloid leukaemia, unspecified	0.003	0.997	0.000
C92.7 Other myeloid leukaemia	0.003	0.997	0.000
C50.9 Breast, unspecified	0.003	0.997	0.000
Z35.8 Supervision of other high-risk pregnancies	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.003	0.997	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.003	0.997	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.003	0.997	0.000
C92.5 Acute myelomonocytic leukaemia	0.003	0.997	0.000
C92.3 Myeloid sarcoma	0.003	0.997	0.000
C92.2 Subacute myeloid leukaemia	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.997	0.001
S81 Open wound of lower leg	0.000	0.997	0.003
C50.2 Upper-inner quadrant of breast	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.997	0.002
N80.3 Endometriosis of pelvic peritoneum	0.000	0.997	0.003
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.002	0.997	0.000
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000
R50.0 Fever with chills	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.001	0.997	0.001
Y83.4 Other reconstructive surgery	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.001
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
A08 Viral and other specified intestinal infections	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.001	0.998	0.001
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
R26.3 Immobility	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
S09.8 Other specified injuries of head	0.000	0.998	0.002
C50-C50 Malignant neoplasm of breast	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
A08.5 Other specified intestinal infections	0.000	0.998	0.002
A08.3 Other viral enteritis	0.000	0.998	0.002
A08.2 Adenoviral enteritis	0.000	0.998	0.002
A08.0 Rotaviral enteritis	0.000	0.998	0.002
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
M22.8 Other disorders of patella	0.000	0.998	0.002
D56.1 Beta thalassaemia	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
F43.0 Acute stress reaction	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.998	0.002
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
D07.5 Prostate	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.001	0.998	0.000
R26.1 Paralytic gait	0.001	0.998	0.000
F52.0 Lack or loss of sexual desire	0.000	0.998	0.001
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
J86.0 Pyothorax with fistula	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
G82.3 Flaccid tetraplegia	0.000	0.998	0.001
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.998	0.000
K00.9 Disorder of tooth development, unspecified	0.002	0.998	0.000
N76.0 Acute vaginitis	0.001	0.998	0.000
G82.1 Spastic paraplegia	0.000	0.998	0.001
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.001
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.001
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.001
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.001
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.001
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
T79.9 Unspecified early complication of trauma	0.001	0.998	0.000
T79.4 Traumatic shock	0.001	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.001	0.998	0.000
T79.1 Fat embolism (traumatic)	0.001	0.998	0.000
T79.0 Air embolism (traumatic)	0.001	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.001	0.998	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.998	0.000
C45.0 Mesothelioma of pleura	0.001	0.998	0.000
C45 Mesothelioma	0.001	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
D07.2 Vagina	0.000	0.999	0.001
M92.7 Juvenile osteochondrosis of metatarsus	0.001	0.999	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.999	0.000
G82.4 Spastic tetraplegia	0.000	0.999	0.001
G82.0 Flaccid paraplegia	0.000	0.999	0.001
L28.0 Lichen simplex chronicus	0.001	0.999	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.999	0.001
A87.9 Viral meningitis, unspecified	0.001	0.999	0.000
M21.8 Other specified acquired deformities of limbs	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
D07.4 Penis	0.000	0.999	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
T79.5 Traumatic anuria	0.001	0.999	0.000
V86.5 Driver of all-terrain or other off-road motor vehicle injured in nontraffic accident	0.001	0.999	0.000
X59.4 Street and highway	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.001	0.999	0.000
R26.0 Ataxic gait	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.001	0.999	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.001	0.999	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
K81.1 Chronic cholecystitis	0.000	0.999	0.001
D61 Other aplastic anaemias	0.001	0.999	0.000
K86 Other diseases of pancreas	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
C45.7 Mesothelioma of other sites	0.001	0.999	0.000
C50.3 Lower-inner quadrant of breast	0.001	0.999	0.000
F43.8 Other reactions to severe stress	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.001	0.999	0.000
M85.8 Other specified disorders of bone density and structure	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.999	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.000	0.999	0.001
S65.5 Injury of blood vessel(s) of other finger	0.001	0.999	0.000
T14.1 Open wound of unspecified body region	0.000	0.999	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.999	0.001
D84 Other immunodeficiencies	0.001	0.999	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.999	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.999	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.999	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.999	0.000
D61.1 Drug-induced aplastic anaemia	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
F33.9 Recurrent depressive disorder, unspecified	0.001	0.999	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.001	0.999	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.999	0.001
Q15.0 Congenital glaucoma	0.001	0.999	0.000
H54 Blindness and low vision	0.001	0.999	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.999	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.999	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.999	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.999	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.999	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.999	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.000	0.999	0.001
M72 Fibroblastic disorders	0.001	0.999	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.999	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.999	0.000
C49.4 Connective and soft tissue of abdomen	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.001	0.999	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.001	0.999	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.999	0.001
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.001	0.999	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.999	0.001
C82.2 Large cell, follicular	0.001	0.999	0.000
D53.9 Nutritional anaemia, unspecified	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
F45.4 Persistent somatoform pain disorder	0.001	0.999	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.999	0.001
S66.8 Injury of other muscles and tendons at wrist and hand level	0.001	0.999	0.000
D86 Sarcoidosis	0.001	0.999	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
D13.2 Duodenum	0.000	0.999	0.001
D61.8 Other specified aplastic anaemias	0.001	0.999	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.999	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.999	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.001	0.999	0.000
O30.0 Twin pregnancy	0.000	0.999	0.001
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.999	0.001
C82.4 Follicular lymphoma grade IIIb	0.001	0.999	0.000
C82.3 Follicular lymphoma grade IIIa	0.001	0.999	0.000
D61.0 Constitutional aplastic anaemia	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
J92.9 Pleural plaque without asbestos	0.000	0.999	0.001
M72.5 Fasciitis, not elsewhere classified	0.001	0.999	0.000
F42 Obsessive-compulsive disorder	0.001	0.999	0.000
C49.0 Connective and soft tissue of head, face and neck	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
G62.9 Polyneuropathy, unspecified	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
I82.3 Embolism and thrombosis of renal vein	0.001	0.999	0.000
T79.6 Traumatic ischaemia of muscle	0.001	0.999	0.000
C82.0 Small cleaved cell, follicular	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.000	0.999	0.001
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
M72.9 Fibroblastic disorder, unspecified	0.001	0.999	0.000
M72.8 Other fibroblastic disorders	0.001	0.999	0.000
M72.6 Necrotizing fasciitis	0.001	0.999	0.000
M72.4 Pseudosarcomatous fibromatosis	0.001	0.999	0.000
M72.3 Nodular fasciitis	0.001	0.999	0.000
F60 Specific personality disorders	0.001	0.999	0.000
M72.58 Fasciitis, not elsewhere classified-Other	0.001	0.999	0.000
C82.6 Cutaneous follicle centre lymphoma	0.001	0.999	0.000
C82.5 Diffuse follicle centre lymphoma	0.001	0.999	0.000
D07.6 Other and unspecified male genital organs	0.000	0.999	0.001
D07.3 Other and unspecified female genital organs	0.000	0.999	0.001
D07.0 Endometrium	0.000	0.999	0.001
D84.1 Defects in the complement system	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations