TreeWAS – Variant ID: rs470234

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.094	0.906
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.102	0.898
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.105	0.895
T50.9 Other and unspecified drugs, medicaments and biological substances	0.115	0.885
T43.2 Other and unspecified antidepressants	0.127	0.873
T46 Poisoning by agents primarily affecting the cardiovascular system	0.169	0.831
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.214	0.786
T46.4 Angiotensin-converting-enzyme inhibitors	0.220	0.780
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.222	0.778
T43.0 Tricyclic and tetracyclic antidepressants	0.236	0.764
T43.5 Other and unspecified antipsychotics and neuroleptics	0.252	0.748
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.260	0.740
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.272	0.728
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.288	0.712
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.293	0.707
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.294	0.706
T50.6 Antidotes and chelating agents, not elsewhere classified	0.295	0.705
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.300	0.700
T43.4 Butyrophenone and thioxanthene neuroleptics	0.308	0.692
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.325	0.675
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.327	0.673
T50.1 Loop [high-ceiling] diuretics	0.329	0.670
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.337	0.663
T47.1 Other antacids and anti-gastric-secretion drugs	0.339	0.661
T43.6 Psychostimulants with abuse potential	0.346	0.653
T43.8 Other psychotropic drugs, not elsewhere classified	0.356	0.644
T50.7 Analeptics and opioid receptor antagonists	0.358	0.642
T50.5 Appetite depressants	0.358	0.642
T50.3 Electrolytic, caloric and water-balance agents	0.358	0.642
T50.0 Mineralocorticoids and their antagonists	0.358	0.642
T42.3 Barbiturates	0.360	0.640
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.361	0.639
T50.4 Drugs affecting uric acid metabolism	0.365	0.635
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.366	0.634
T46.3 Coronary vasodilators, not elsewhere classified	0.370	0.630
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.378	0.622
T41 Poisoning by anaesthetics and therapeutic gases	0.379	0.621
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.382	0.618
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.384	0.616
T50.8 Diagnostic agents	0.392	0.607
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.393	0.607
T43.3 Phenothiazine antipsychotics and neuroleptics	0.401	0.599
T36 Poisoning by systemic antibiotics	0.402	0.598
T46.8 Antivaricose drugs, including sclerosing agents	0.404	0.596
T46.7 Peripheral vasodilators	0.404	0.596
T40.2 Other opioids	0.409	0.591
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.414	0.586
T43.9 Psychotropic drug, unspecified	0.415	0.585
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.417	0.583
T42.0 Hydantoin derivatives	0.419	0.581
T40.5 Cocaine	0.420	0.580
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.425	0.575
T46.5 Other antihypertensive drugs, not elsewhere classified	0.425	0.575
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.426	0.574
T46.1 Calcium-channel blockers	0.429	0.571
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.432	0.568
T45.2 Vitamins, not elsewhere classified	0.434	0.566
T42.5 Mixed antiepileptics, not elsewhere classified	0.436	0.564
T42.2 Succinimides and oxazolidinediones	0.436	0.564
T42.4 Benzodiazepines	0.439	0.561
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.440	0.560
T40.1 Heroin	0.442	0.558
T39.4 Antirheumatics, not elsewhere classified	0.442	0.558
T39.2 Pyrazolone derivatives	0.442	0.558
T45.0 Antiallergic and antiemetic drugs	0.445	0.555
T38.0 Glucocorticoids and synthetic analogues	0.452	0.548
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.456	0.544
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.457	0.543
T45.1 Antineoplastic and immunosuppressive drugs	0.460	0.540
T15-T19 Effects of foreign body entering through natural orifice	0.461	0.539
T18 Foreign body in alimentary tract	0.463	0.537
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.466	0.534
T18.1 Foreign body in oesophagus	0.467	0.533
T47.0 Histamine H(2)-receptor antagonists	0.468	0.532
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.470	0.530
T47.8 Other agents primarily affecting the gastro-intestinal system	0.470	0.530
T47.7 Emetics	0.470	0.530
T47.5 Digestants	0.470	0.530
T47.3 Saline and osmotic laxatives	0.470	0.530
T45.9 Primarily systemic and haematological agent, unspecified	0.478	0.522
T45.8 Other primarily systemic and haematological agents	0.478	0.522
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.478	0.522
T45.6 Fibrinolysis-affecting drugs	0.478	0.522
T45.4 Iron and its compounds	0.478	0.522
T45.3 Enzymes, not elsewhere classified	0.478	0.522
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.479	0.521
T39.0 Salicylates	0.484	0.516
T38.5 Other oestrogens and progestogens	0.485	0.515
T47.4 Other laxatives	0.485	0.515
T45.5 Anticoagulants	0.485	0.515
T38.8 Other and unspecified hormones and their synthetic substitutes	0.487	0.513
T48.5 Anti-common-cold drugs	0.487	0.512
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.491	0.509
T38.1 Thyroid hormones and substitutes	0.492	0.508
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.493	0.507
T40.8 Lysergide [LSD]	0.493	0.507
T40.7 Cannabis (derivatives)	0.493	0.507
T40.0 Opium	0.493	0.507
T38.9 Other and unspecified hormone antagonists	0.493	0.506
T38.7 Androgens and anabolic congeners	0.493	0.506
T38.4 Oral contraceptives	0.493	0.506
T38.2 Antithyroid drugs	0.493	0.506
T47.6 Antidiarrhoeal drugs	0.494	0.505
S60-S69 Injuries to the wrist and hand	0.495	0.505
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.499	0.501
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.502	0.498
T00-T07 Injuries involving multiple body regions	0.502	0.498
T42.1 Iminostilbenes	0.505	0.495
S60 Superficial injury of wrist and hand	0.510	0.490
T40.3 Methadone	0.511	0.489
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.513	0.487
T85 Complications of other internal prosthetic devices, implants and grafts	0.514	0.486
T49.9 Topical agent, unspecified	0.516	0.484
T49.8 Other topical agents	0.516	0.484
T49.7 Dental drugs, topically applied	0.516	0.484
T49.6 Otorhinolaryngological drugs and preparations	0.516	0.484
T49.5 Ophthalmological drugs and preparations	0.516	0.484
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.516	0.484
T49.3 Emollients, demulcents and protectants	0.516	0.484
T49.2 Local astringents and local detergents	0.516	0.484
T49.1 Antipruritics	0.516	0.484
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.518	0.482
T48.4 Expectorants	0.518	0.482
T48.3 Antitussives	0.518	0.482
T48.2 Other and unspecified agents primarily acting on muscles	0.518	0.482
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.518	0.482
T48.0 Oxytocic drugs	0.518	0.482
T86 Failure and rejection of transplanted organs and tissues	0.524	0.476
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.525	0.475
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.525	0.475
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.525	0.475
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.525	0.475
T44.1 Other parasympathomimetics [cholinergics]	0.525	0.475
T44.0 Anticholinesterase agents	0.525	0.475
T39.1 4-Aminophenol derivatives	0.525	0.475
T80 Complications following infusion, transfusion and therapeutic injection	0.526	0.474
T48.6 Antiasthmatics, not elsewhere classified	0.526	0.473
T47.2 Stimulant laxatives	0.528	0.472
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.528	0.472
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.528	0.472
S90-S99 Injuries to the ankle and foot	0.535	0.465
S60.9 Superficial injury of wrist and hand, unspecified	0.540	0.460
S64 Injury of nerves at wrist and hand level	0.544	0.456
T87 Complications peculiar to reattachment and amputation	0.551	0.449
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.553	0.447
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.553	0.447
T00 Superficial injuries involving multiple body regions	0.554	0.446
T41.5 Therapeutic gases	0.554	0.445
T41.4 Anaesthetic, unspecified	0.554	0.445
T41.3 Local anaesthetics	0.554	0.445
T41.1 Intravenous anaesthetics	0.554	0.445
T41.0 Inhaled anaesthetics	0.554	0.445
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.556	0.443
T37.5 Antiviral drugs	0.556	0.443
T37.4 Anthelminthics	0.556	0.443
T37.3 Other antiprotozoal drugs	0.556	0.443
T37.1 Antimycobacterial drugs	0.556	0.443
T37.0 Sulphonamides	0.556	0.443
T36.4 Tetracyclines	0.560	0.440
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.562	0.438
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.563	0.437
T36.3 Macrolides	0.565	0.434
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.567	0.433
T18.0 Foreign body in mouth	0.567	0.433
T36.9 Systemic antibiotic, unspecified	0.571	0.429
T36.7 Antifungal antibiotics, systemically used	0.571	0.429
T36.6 Rifamycins	0.571	0.429
T36.5 Aminoglycosides	0.571	0.429
T36.2 Chloramphenicol group	0.571	0.429
T37.8 Other specified systemic anti-infectives and antiparasitics	0.571	0.428
T37.2 Antimalarials and drugs acting on other blood protozoa	0.572	0.428
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.575	0.424
T41.2 Other and unspecified general anaesthetics	0.583	0.417
T16 Foreign body in ear	0.585	0.415
T40.6 Other and unspecified narcotics	0.585	0.415
T36.8 Other systemic antibiotics	0.586	0.414
T18.9 Foreign body in alimentary tract, part unspecified	0.586	0.414
S62 Fracture at wrist and hand level	0.590	0.410
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.593	0.407
T36.0 Penicillins	0.593	0.406
S64.1 Injury of median nerve at wrist and hand level	0.597	0.403
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.599	0.401
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.599	0.400
S60.2 Contusion of other parts of wrist and hand	0.601	0.399
T18.3 Foreign body in small intestine	0.602	0.398
T83.2 Mechanical complication of graft of urinary organ	0.602	0.397
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.603	0.397
T86.8 Failure and rejection of other transplanted organs and tissues	0.604	0.396
S60.7 Multiple superficial injuries of wrist and hand	0.604	0.396
S64.0 Injury of ulnar nerve at wrist and hand level	0.605	0.395
T26-T28 Burns and corrosions confined to eye and internal organs	0.607	0.393
S96 Injury of muscle and tendon at ankle and foot level	0.607	0.393
T18.5 Foreign body in anus and rectum	0.607	0.392
T33-T35 Frostbite	0.610	0.390
T86.0 Bone-marrow transplant rejection	0.610	0.390
T19 Foreign body in genito-urinary tract	0.610	0.389
S60.0 Contusion of finger(s) without damage to nail	0.612	0.388
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.612	0.388
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.612	0.388
T02 Fractures involving multiple body regions	0.613	0.387
T01 Open wounds involving multiple body regions	0.613	0.387
T83.0 Mechanical complication of urinary (indwelling) catheter	0.615	0.385
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.615	0.385
T18.8 Foreign body in other and multiple parts of alimentary tract	0.615	0.385
T18.4 Foreign body in colon	0.615	0.385
S92 Fracture of foot, except ankle	0.615	0.385
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.617	0.383
S64.3 Injury of digital nerve of thumb	0.617	0.383
T83.3 Mechanical complication of intra-uterine contraceptive device	0.618	0.382
S66 Injury of muscle and tendon at wrist and hand level	0.619	0.381
T15 Foreign body on external eye	0.620	0.380
T40.4 Other synthetic narcotics	0.620	0.380
T00.9 Multiple superficial injuries, unspecified	0.622	0.378
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.623	0.377
T87.6 Other and unspecified complications of amputation stump	0.627	0.373
S68 Traumatic amputation of wrist and hand	0.627	0.373
T79-T79 Certain early complications of trauma	0.629	0.371
S62.3 Fracture of other metacarpal bone	0.629	0.371
S69 Other and unspecified injuries of wrist and hand	0.630	0.370
S91 Open wound of ankle and foot	0.630	0.370
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.634	0.366
T18.2 Foreign body in stomach	0.634	0.366
S98 Traumatic amputation of ankle and foot	0.636	0.364
T88 Other complications of surgical and medical care, not elsewhere classified	0.636	0.364
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.641	0.359
T05 Traumatic amputations involving multiple body regions	0.643	0.357
T04 Crushing injuries involving multiple body regions	0.643	0.357
T03 Dislocations, sprains and strains involving multiple body regions	0.643	0.357
T07 Unspecified multiple injuries	0.643	0.357
T87.4 Infection of amputation stump	0.643	0.356
T00.8 Superficial injuries involving other combinations of body regions	0.647	0.353
S60.8 Other superficial injuries of wrist and hand	0.648	0.352
S64.7 Injury of multiple nerves at wrist and hand level	0.650	0.350
S62.30 Fracture of other metacarpal bone (closed)	0.650	0.350
T06 Other injuries involving multiple body regions, not elsewhere classified	0.652	0.348
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.653	0.347
S20-S29 Injuries to the thorax	0.654	0.346
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.654	0.346
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.655	0.345
T86.4 Liver transplant failure and rejection	0.657	0.343
T86.3 Heart-lung transplant failure and rejection	0.659	0.341
T86.2 Heart transplant failure and rejection	0.659	0.341
S92.3 Fracture of metatarsal bone	0.660	0.340
T80.6 Other serum reactions	0.660	0.340
T80.5 Anaphylactic shock due to serum	0.660	0.340
T80.4 Rh incompatibility reaction	0.660	0.340
T80.3 ABO incompatibility reaction	0.660	0.340
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.660	0.340
T66-T78 Other and unspecified effects of external causes	0.663	0.337
S99 Other and unspecified injuries of ankle and foot	0.665	0.335
S65 Injury of blood vessels at wrist and hand level	0.666	0.333
S95 Injury of blood vessels at ankle and foot level	0.667	0.333
S94 Injury of nerves at ankle and foot level	0.667	0.333
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.668	0.332
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.668	0.331
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.670	0.330
S64.9 Injury of unspecified nerve at wrist and hand level	0.673	0.327
S64.8 Injury of other nerves at wrist and hand level	0.673	0.327
S60.1 Contusion of finger(s) with damage to nail	0.673	0.326
S67 Crushing injury of wrist and hand	0.674	0.326
T17 Foreign body in respiratory tract	0.674	0.326
T87.2 Complications of other reattached body part	0.678	0.322
T87.1 Complications of reattached (part of) lower extremity	0.678	0.322
T87.0 Complications of reattached (part of) upper extremity	0.678	0.322
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.679	0.321
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.680	0.320
T00.0 Superficial injuries involving head with neck	0.680	0.320
S62.2 Fracture of first metacarpal bone	0.680	0.320
S62.6 Fracture of other finger	0.681	0.319
S91.2 Open wound of toe(s) with damage to nail	0.684	0.316
T86.1 Kidney transplant failure and rejection	0.685	0.315
S27 Injury of other and unspecified intrathoracic organs	0.687	0.313
T87.3 Neuroma of amputation stump	0.688	0.311
S62.8 Fracture of other and unspecified parts of wrist and hand	0.689	0.311
T20-T25 Burns and corrosions of external body surface, specified by site	0.689	0.311
S92.30 Fracture of metatarsal bone (closed)	0.691	0.309
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.693	0.307
T01.8 Open wounds involving other combinations of body regions	0.694	0.306
T87.5 Necrosis of amputation stump	0.694	0.306
S68.0 Traumatic amputation of thumb (complete)(partial)	0.694	0.306
S96.8 Injury of other muscles and tendons at ankle and foot level	0.694	0.306
T59 Toxic effect of other gases, fumes and vapours	0.694	0.305
S91.3 Open wound of other parts of foot	0.695	0.305
S97 Crushing injury of ankle and foot	0.695	0.305
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.696	0.304
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.698	0.302
T02.8 Fractures involving other combinations of body regions	0.698	0.301
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.699	0.301
T02.4 Fractures involving multiple regions of both upper limbs	0.699	0.301
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.699	0.301
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.700	0.300
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.701	0.299
T85.2 Mechanical complication of intraocular lens	0.703	0.297
S62.7 Multiple fractures of fingers	0.706	0.294
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.707	0.293
T82.4 Mechanical complication of vascular dialysis catheter	0.707	0.293
S98.1 Traumatic amputation of one toe	0.708	0.292
T29 Burns and corrosions of multiple body regions	0.708	0.292
T19.0 Foreign body in urethra	0.708	0.292
T88.9 Complication of surgical and medical care, unspecified	0.708	0.292
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.708	0.292
T51 Toxic effect of alcohol	0.709	0.291
T15.0 Foreign body in cornea	0.709	0.291
T19.2 Foreign body in vulva and vagina	0.710	0.290
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.710	0.289
S92.2 Fracture of other tarsal bone(s)	0.711	0.289
T63 Toxic effect of contact with venomous animals	0.713	0.287
T26 Burn and corrosion confined to eye and adnexa	0.715	0.285
S92.5 Fracture of other toe	0.716	0.284
S92.9 Fracture of foot, unspecified	0.717	0.283
T28 Burn and corrosion of other internal organs	0.718	0.282
T27 Burn and corrosion of respiratory tract	0.718	0.282
T54 Toxic effect of corrosive substances	0.718	0.282
T01.3 Open wounds involving multiple regions of lower limb(s)	0.718	0.282
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.718	0.282
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.718	0.282
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.718	0.282
S69.7 Multiple injuries of wrist and hand	0.718	0.281
T30 Burn and corrosion, body region unspecified	0.719	0.281
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.719	0.281
T35 Frostbite involving multiple body regions and unspecified frostbite	0.720	0.280
T34 Frostbite with tissue necrosis	0.720	0.280
T33 Superficial frostbite	0.720	0.280
T19.9 Foreign body in genito-urinary tract, part unspecified	0.720	0.279
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.720	0.279
T19.3 Foreign body in uterus [any part]	0.720	0.279
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.721	0.279
T02.9 Multiple fractures, unspecified	0.722	0.278
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.722	0.278
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.722	0.278
T02.3 Fractures involving multiple regions of one lower limb	0.722	0.278
T02.1 Fractures involving thorax with lower back and pelvis	0.722	0.278
T02.0 Fractures involving head with neck	0.722	0.278
T01.9 Multiple open wounds, unspecified	0.722	0.278
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.722	0.278
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.722	0.278
T01.0 Open wounds involving head with neck	0.722	0.278
T60 Toxic effect of pesticides	0.724	0.276
T57 Toxic effect of other inorganic substances	0.724	0.276
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.724	0.276
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.724	0.276
S62.1 Fracture of other carpal bone(s)	0.724	0.276
T01.2 Open wounds involving multiple regions of upper limb(s)	0.724	0.276
T32 Corrosions classified according to extent of body surface involved	0.725	0.275
T88.7 Unspecified adverse effect of drug or medicament	0.726	0.274
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.726	0.273
T83.1 Mechanical complication of other urinary devices and implants	0.727	0.273
T15.8 Foreign body in other and multiple parts of external eye	0.727	0.273
T02.5 Fractures involving multiple regions of both lower limbs	0.727	0.273
T61 Toxic effect of noxious substances eaten as seafood	0.729	0.271
T52 Toxic effect of organic solvents	0.729	0.271
T56 Toxic effect of metals	0.729	0.271
S50-S59 Injuries to the elbow and forearm	0.730	0.270
T70 Effects of air pressure and water pressure	0.730	0.270
S92.7 Multiple fractures of foot	0.730	0.269
T55 Toxic effect of soaps and detergents	0.731	0.269
S92.4 Fracture of great toe	0.731	0.269
T68 Hypothermia	0.731	0.269
T25 Burn and corrosion of ankle and foot	0.731	0.268
T62 Toxic effect of other noxious substances eaten as food	0.731	0.268
S27.1 Traumatic haemothorax	0.732	0.268
S62.4 Multiple fractures of metacarpal bones	0.732	0.268
S90 Superficial injury of ankle and foot	0.732	0.268
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.732	0.268
S62.0 Fracture of navicular [scaphoid] bone of hand	0.732	0.267
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.733	0.267
S68.8 Traumatic amputation of other parts of wrist and hand	0.733	0.267
S68.4 Traumatic amputation of hand at wrist level	0.733	0.267
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.733	0.267
S92.1 Fracture of talus	0.733	0.267
S10-S19 Injuries to the neck	0.734	0.265
S91.7 Multiple open wounds of ankle and foot	0.735	0.265
T02.2 Fractures involving multiple regions of one upper limb	0.735	0.265
T88.3 Malignant hyperthermia due to anaesthesis	0.735	0.265
T15.1 Foreign body in conjunctival sac	0.735	0.265
T82.0 Mechanical complication of heart valve prosthesis	0.736	0.264
S27.2 Traumatic heamopneumothorax	0.736	0.264
S69.8 Other specified injuries of wrist and hand	0.737	0.263
S98.4 Traumatic amputation of foot, level unspecified	0.739	0.261
S98.3 Traumatic amputation of other parts of foot	0.739	0.261
S98.2 Traumatic amputation of two or more toes	0.739	0.261
S98.0 Traumatic amputation of foot at ankle level	0.739	0.261
T88.1 Other complications following immunisation, not elsewhere classified	0.739	0.261
T88.0 Infection following immunisation	0.739	0.261
T58 Toxic effect of carbon monoxide	0.739	0.260
T66 Unspecified effects of radiation	0.739	0.260
T31 Burns classified according to extent of body surface involved	0.741	0.259
S69.9 Unspecified injury of wrist and hand	0.742	0.258
T17.2 Foreign body in pharynx	0.743	0.257
T59.9 Gases, fumes and vapours, unspecified	0.743	0.256
T19.1 Foreign body in bladder	0.744	0.256
T03.9 Multiple dislocations, sprains and strains, unspecified	0.744	0.256
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.744	0.256
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.744	0.256
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.744	0.256
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.744	0.256
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.744	0.256
T03.0 Dislocations, sprains and strains involving head with neck	0.744	0.256
T04.9 Multiple crushing injuries, unspecified	0.744	0.256
T04.8 Crushing injuries involving other combinations of body regions	0.744	0.256
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.744	0.256
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.744	0.256
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.744	0.256
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.744	0.256
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.744	0.256
T04.0 Crushing injuries involving head with neck	0.744	0.256
T05.9 Multiple traumatic amputations, unspecified	0.744	0.256
T05.8 Traumatic amputations involving other combinations of body regions	0.744	0.256
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.744	0.256
T05.5 Traumatic amputation of both legs [any level]	0.744	0.256
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.744	0.256
T05.3 Traumatic amputation of both feet	0.744	0.256
T05.2 Traumatic amputation of both arms [any level]	0.744	0.256
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.744	0.256
T05.0 Traumatic amputation of both hands	0.744	0.256
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.744	0.255
S62.20 Fracture of first metacarpal bone (closed)	0.744	0.255
T15.9 Foreign body on external eye, unspecified	0.746	0.254
S64.4 Injury of digital nerve of other finger	0.746	0.254
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.748	0.252
T88.5 Other complications of anaesthesia	0.749	0.251
T51.0 Ethanol	0.749	0.251
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.750	0.250
S26 Injury of heart	0.750	0.250
S27.3 Other injuries of lung	0.750	0.250
T06.8 Other specified injuries involving multiple body regions	0.750	0.250
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.750	0.250
T06.3 Injuries of blood vessels involving multiple body regions	0.750	0.250
T06.2 Injuries of nerves involving multiple body regions	0.750	0.250
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.750	0.250
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.750	0.250
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.752	0.248
S25 Injury of blood vessels of thorax	0.752	0.248
S91.1 Open wound of toe(s) without damage to nail	0.753	0.247
S65.0 Injury of ulnar artery at wrist and hand level	0.753	0.246
T79 Certain early complications of trauma, not elsewhere classified	0.753	0.247
T17.3 Foreign body in larynx	0.754	0.245
S65.4 Injury of blood vessel(s) of thumb	0.755	0.245
S92.31 Fracture of metatarsal bone (open)	0.756	0.244
T65 Toxic effect of other and unspecified substances	0.756	0.244
S99.9 Unspecified injury of ankle and foot	0.756	0.244
T80.2 Infections following infusion, transfusion and therapeutic injection	0.756	0.243
S62.61 Fracture of other finger (open)	0.758	0.242
T74 Maltreatment syndromes	0.758	0.242
T73 Effects of other deprivation	0.758	0.242
T69 Other effects of reduced temperature	0.758	0.242
T67 Effects of heat and light	0.758	0.242
S62.60 Fracture of other finger (closed)	0.758	0.242
T06.4 Injuries of muscles and tendons involving multiple body regions	0.759	0.241
S99.7 Multiple injuries of ankle and foot	0.759	0.240
T02.80 Fractures involving other combinations of body regions (closed)	0.760	0.240
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.760	0.239
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.760	0.239
S20 Superficial injury of thorax	0.761	0.239
S99.8 Other specified injuries of ankle and foot	0.761	0.239
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.761	0.239
S65.8 Injury of other blood vessels at wrist and hand level	0.761	0.239
S65.7 Injury of multiple blood vessels at wrist and hand level	0.761	0.239
S65.3 Injury of deep palmar arch	0.761	0.239
S65.2 Injury of superficial palmar arch	0.761	0.239
S94.9 Injury of unspecified nerve at ankle and foot level	0.761	0.239
S94.8 Injury of other nerves at ankle and foot level	0.761	0.239
S94.7 Injury of multiple nerves at ankle and foot level	0.761	0.239
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.761	0.239
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.761	0.239
S94.1 Injury of medial plantar nerve	0.761	0.239
S94.0 Injury of lateral plantar nerve	0.761	0.239
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.761	0.239
S95.8 Injury of other blood vessels at ankle and foot level	0.761	0.239
S95.7 Injury of multiple blood vessels at ankle and foot level	0.761	0.239
S95.2 Injury of dorsal vein of foot	0.761	0.239
S95.1 Injury of plantar artery of foot	0.761	0.239
S95.0 Injury of dorsal artery of foot	0.761	0.239
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.761	0.239
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.764	0.236
T17.4 Foreign body in trachea	0.766	0.234
T17.1 Foreign body in nostril	0.766	0.234
T17.0 Foreign body in nasal sinus	0.766	0.234
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.767	0.233
S92.0 Fracture of calcaneus	0.767	0.233
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.768	0.232
S80-S89 Injuries to the knee and lower leg	0.768	0.232
S24 Injury of nerves and spinal cord at thorax level	0.769	0.231
S65.5 Injury of blood vessel(s) of other finger	0.769	0.231
S62.31 Fracture of other metacarpal bone (open)	0.769	0.230
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.770	0.230
S62.21 Fracture of first metacarpal bone (open)	0.770	0.229
T63.4 Venom of other arthropods	0.772	0.228
T25.2 Burn of second degree of ankle and foot	0.772	0.228
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.773	0.227
T75 Effects of other external causes	0.774	0.226
S27.8 Injury of other specified intrathoracic organs	0.774	0.226
T17.5 Foreign body in bronchus	0.775	0.225
S92.50 Fracture of other toe (closed)	0.775	0.225
S27.9 Injury of unspecified intrathoracic organ	0.776	0.224
S27.7 Multiple injuries of intrathoracic organs	0.776	0.224
S27.6 Injury of pleura	0.776	0.224
S27.5 Injury of thoracic trachea	0.776	0.224
S27.4 Injury of bronchus	0.776	0.224
T71 Asphyxiation	0.776	0.224

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations