TreeWAS – Variant ID: rs470292

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.065	0.935
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.071	0.929
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.075	0.925
T50.9 Other and unspecified drugs, medicaments and biological substances	0.083	0.917
T43.2 Other and unspecified antidepressants	0.095	0.905
T46 Poisoning by agents primarily affecting the cardiovascular system	0.136	0.864
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.185	0.815
T46.4 Angiotensin-converting-enzyme inhibitors	0.190	0.810
T43.0 Tricyclic and tetracyclic antidepressants	0.198	0.802
T43.5 Other and unspecified antipsychotics and neuroleptics	0.210	0.790
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.212	0.788
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.217	0.783
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.235	0.765
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.259	0.741
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.263	0.737
T50.6 Antidotes and chelating agents, not elsewhere classified	0.272	0.728
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.279	0.721
T43.4 Butyrophenone and thioxanthene neuroleptics	0.285	0.715
T47.1 Other antacids and anti-gastric-secretion drugs	0.288	0.712
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.294	0.706
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.304	0.696
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.306	0.694
T50.1 Loop [high-ceiling] diuretics	0.307	0.693
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.315	0.685
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.318	0.682
T43.6 Psychostimulants with abuse potential	0.325	0.675
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.331	0.669
T43.8 Other psychotropic drugs, not elsewhere classified	0.334	0.666
T50.7 Analeptics and opioid receptor antagonists	0.337	0.663
T50.5 Appetite depressants	0.337	0.663
T50.3 Electrolytic, caloric and water-balance agents	0.337	0.663
T50.0 Mineralocorticoids and their antagonists	0.337	0.663
T42.3 Barbiturates	0.337	0.663
T50.4 Drugs affecting uric acid metabolism	0.344	0.656
T46.3 Coronary vasodilators, not elsewhere classified	0.345	0.655
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.357	0.643
T41 Poisoning by anaesthetics and therapeutic gases	0.359	0.641
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.362	0.638
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.362	0.638
T50.8 Diagnostic agents	0.372	0.628
T46.8 Antivaricose drugs, including sclerosing agents	0.381	0.619
T46.7 Peripheral vasodilators	0.381	0.619
T43.3 Phenothiazine antipsychotics and neuroleptics	0.383	0.617
T36 Poisoning by systemic antibiotics	0.384	0.616
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.386	0.614
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.391	0.609
T43.9 Psychotropic drug, unspecified	0.395	0.605
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.396	0.604
T42.0 Hydantoin derivatives	0.398	0.602
T40.2 Other opioids	0.402	0.598
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.402	0.598
T46.5 Other antihypertensive drugs, not elsewhere classified	0.403	0.597
T45.2 Vitamins, not elsewhere classified	0.406	0.594
T46.1 Calcium-channel blockers	0.407	0.593
T40.5 Cocaine	0.409	0.591
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.410	0.590
T45.1 Antineoplastic and immunosuppressive drugs	0.413	0.587
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.413	0.587
T42.5 Mixed antiepileptics, not elsewhere classified	0.416	0.584
T42.2 Succinimides and oxazolidinediones	0.416	0.584
T45.0 Antiallergic and antiemetic drugs	0.418	0.582
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.420	0.580
T38.0 Glucocorticoids and synthetic analogues	0.426	0.574
T42.4 Benzodiazepines	0.428	0.572
T40.1 Heroin	0.431	0.569
T39.4 Antirheumatics, not elsewhere classified	0.435	0.565
T39.2 Pyrazolone derivatives	0.435	0.565
T47.0 Histamine H(2)-receptor antagonists	0.437	0.563
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.438	0.561
T47.8 Other agents primarily affecting the gastro-intestinal system	0.438	0.561
T47.7 Emetics	0.438	0.561
T47.5 Digestants	0.438	0.561
T47.3 Saline and osmotic laxatives	0.438	0.561
T45.9 Primarily systemic and haematological agent, unspecified	0.451	0.548
T45.8 Other primarily systemic and haematological agents	0.451	0.548
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.451	0.548
T45.6 Fibrinolysis-affecting drugs	0.451	0.548
T45.4 Iron and its compounds	0.451	0.548
T45.3 Enzymes, not elsewhere classified	0.451	0.548
T47.4 Other laxatives	0.455	0.545
T45.5 Anticoagulants	0.459	0.540
T38.5 Other oestrogens and progestogens	0.460	0.540
T38.8 Other and unspecified hormones and their synthetic substitutes	0.462	0.538
T47.6 Antidiarrhoeal drugs	0.465	0.535
T38.1 Thyroid hormones and substitutes	0.468	0.532
T38.9 Other and unspecified hormone antagonists	0.469	0.531
T38.7 Androgens and anabolic congeners	0.469	0.531
T38.4 Oral contraceptives	0.469	0.531
T38.2 Antithyroid drugs	0.469	0.531
T48.5 Anti-common-cold drugs	0.471	0.529
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.475	0.525
T39.0 Salicylates	0.482	0.518
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.483	0.517
T40.8 Lysergide [LSD]	0.483	0.517
T40.7 Cannabis (derivatives)	0.483	0.517
T40.0 Opium	0.483	0.517
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.485	0.515
T42.1 Iminostilbenes	0.488	0.512
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.488	0.512
T47.2 Stimulant laxatives	0.500	0.499
T49.9 Topical agent, unspecified	0.501	0.499
T49.8 Other topical agents	0.501	0.499
T49.7 Dental drugs, topically applied	0.501	0.499
T49.6 Otorhinolaryngological drugs and preparations	0.501	0.499
T49.5 Ophthalmological drugs and preparations	0.501	0.499
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.501	0.499
T49.3 Emollients, demulcents and protectants	0.501	0.499
T49.2 Local astringents and local detergents	0.501	0.499
T49.1 Antipruritics	0.501	0.499
T40.3 Methadone	0.501	0.498
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.502	0.497
T48.4 Expectorants	0.502	0.497
T48.3 Antitussives	0.502	0.497
T48.2 Other and unspecified agents primarily acting on muscles	0.502	0.497
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.502	0.497
T48.0 Oxytocic drugs	0.502	0.497
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.511	0.489
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.511	0.489
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.511	0.489
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.511	0.489
T44.1 Other parasympathomimetics [cholinergics]	0.511	0.489
T44.0 Anticholinesterase agents	0.511	0.489
T48.6 Antiasthmatics, not elsewhere classified	0.512	0.488
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.515	0.485
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.518	0.482
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.520	0.480
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.520	0.480
T15-T19 Effects of foreign body entering through natural orifice	0.523	0.477
T18 Foreign body in alimentary tract	0.525	0.475
T18.1 Foreign body in oesophagus	0.528	0.472
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.529	0.471
T39.1 4-Aminophenol derivatives	0.537	0.463
T41.5 Therapeutic gases	0.540	0.460
T41.4 Anaesthetic, unspecified	0.540	0.460
T41.3 Local anaesthetics	0.540	0.460
T41.1 Intravenous anaesthetics	0.540	0.460
T41.0 Inhaled anaesthetics	0.540	0.460
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.541	0.459
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.542	0.457
T37.5 Antiviral drugs	0.542	0.457
T37.4 Anthelminthics	0.542	0.457
T37.3 Other antiprotozoal drugs	0.542	0.457
T37.1 Antimycobacterial drugs	0.542	0.457
T37.0 Sulphonamides	0.542	0.457
T36.4 Tetracyclines	0.547	0.453
T36.3 Macrolides	0.552	0.447
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.553	0.447
S60-S69 Injuries to the wrist and hand	0.553	0.447
T36.9 Systemic antibiotic, unspecified	0.558	0.442
T36.7 Antifungal antibiotics, systemically used	0.558	0.442
T36.6 Rifamycins	0.558	0.442
T36.5 Aminoglycosides	0.558	0.442
T36.2 Chloramphenicol group	0.558	0.442
T37.8 Other specified systemic anti-infectives and antiparasitics	0.558	0.442
T37.2 Antimalarials and drugs acting on other blood protozoa	0.558	0.441
T00-T07 Injuries involving multiple body regions	0.560	0.440
S60 Superficial injury of wrist and hand	0.567	0.433
T41.2 Other and unspecified general anaesthetics	0.570	0.430
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.571	0.429
T36.8 Other systemic antibiotics	0.573	0.426
T80 Complications following infusion, transfusion and therapeutic injection	0.575	0.425
T85 Complications of other internal prosthetic devices, implants and grafts	0.577	0.423
T40.6 Other and unspecified narcotics	0.577	0.422
T36.0 Penicillins	0.582	0.418
T86 Failure and rejection of transplanted organs and tissues	0.582	0.418
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.587	0.412
S90-S99 Injuries to the ankle and foot	0.589	0.411
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.590	0.410
S60.9 Superficial injury of wrist and hand, unspecified	0.594	0.406
S64 Injury of nerves at wrist and hand level	0.600	0.400
T87 Complications peculiar to reattachment and amputation	0.605	0.395
T00 Superficial injuries involving multiple body regions	0.605	0.394
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.612	0.388
T40.4 Other synthetic narcotics	0.614	0.385
T18.0 Foreign body in mouth	0.617	0.383
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.620	0.380
T16 Foreign body in ear	0.621	0.379
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.621	0.379
S62 Fracture at wrist and hand level	0.625	0.375
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.626	0.374
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.632	0.368
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.646	0.354
S64.1 Injury of median nerve at wrist and hand level	0.647	0.353
T18.9 Foreign body in alimentary tract, part unspecified	0.647	0.353
S60.2 Contusion of other parts of wrist and hand	0.648	0.352
T18.3 Foreign body in small intestine	0.648	0.352
S60.7 Multiple superficial injuries of wrist and hand	0.650	0.350
T83.2 Mechanical complication of graft of urinary organ	0.650	0.350
T26-T28 Burns and corrosions confined to eye and internal organs	0.652	0.348
T86.8 Failure and rejection of other transplanted organs and tissues	0.652	0.348
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.652	0.348
S96 Injury of muscle and tendon at ankle and foot level	0.653	0.347
T18.5 Foreign body in anus and rectum	0.653	0.347
T33-T35 Frostbite	0.654	0.345
S64.0 Injury of ulnar nerve at wrist and hand level	0.655	0.345
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.655	0.345
T19 Foreign body in genito-urinary tract	0.655	0.345
S60.0 Contusion of finger(s) without damage to nail	0.657	0.343
T86.0 Bone-marrow transplant rejection	0.658	0.342
T01 Open wounds involving multiple body regions	0.658	0.342
T02 Fractures involving multiple body regions	0.658	0.342
T18.8 Foreign body in other and multiple parts of alimentary tract	0.659	0.340
T18.4 Foreign body in colon	0.659	0.340
S92 Fracture of foot, except ankle	0.660	0.340
S66 Injury of muscle and tendon at wrist and hand level	0.661	0.339
S62.3 Fracture of other metacarpal bone	0.662	0.338
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.662	0.338
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.662	0.338
T83.0 Mechanical complication of urinary (indwelling) catheter	0.663	0.337
T15 Foreign body on external eye	0.663	0.336
T83.3 Mechanical complication of intra-uterine contraceptive device	0.664	0.336
S64.3 Injury of digital nerve of thumb	0.665	0.335
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.666	0.334
T00.9 Multiple superficial injuries, unspecified	0.666	0.334
S68 Traumatic amputation of wrist and hand	0.672	0.328
T87.6 Other and unspecified complications of amputation stump	0.672	0.328
T88 Other complications of surgical and medical care, not elsewhere classified	0.673	0.327
T79-T79 Certain early complications of trauma	0.674	0.326
S69 Other and unspecified injuries of wrist and hand	0.674	0.326
S91 Open wound of ankle and foot	0.674	0.325
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.675	0.325
T18.2 Foreign body in stomach	0.676	0.323
S98 Traumatic amputation of ankle and foot	0.678	0.322
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.678	0.322
S62.30 Fracture of other metacarpal bone (closed)	0.681	0.319
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.683	0.317
T05 Traumatic amputations involving multiple body regions	0.684	0.316
T04 Crushing injuries involving multiple body regions	0.684	0.316
T03 Dislocations, sprains and strains involving multiple body regions	0.684	0.316
T07 Unspecified multiple injuries	0.684	0.316
T87.4 Infection of amputation stump	0.686	0.314
T00.8 Superficial injuries involving other combinations of body regions	0.688	0.312
S62.6 Fracture of other finger	0.689	0.311
S60.8 Other superficial injuries of wrist and hand	0.690	0.310
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.691	0.309
T06 Other injuries involving multiple body regions, not elsewhere classified	0.692	0.308
S20-S29 Injuries to the thorax	0.692	0.308
S64.7 Injury of multiple nerves at wrist and hand level	0.693	0.307
T80.6 Other serum reactions	0.695	0.304
T80.5 Anaphylactic shock due to serum	0.695	0.304
T80.4 Rh incompatibility reaction	0.695	0.304
T80.3 ABO incompatibility reaction	0.695	0.304
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.695	0.304
T86.4 Liver transplant failure and rejection	0.698	0.301
T86.3 Heart-lung transplant failure and rejection	0.700	0.300
T86.2 Heart transplant failure and rejection	0.700	0.300
S92.3 Fracture of metatarsal bone	0.700	0.300
T66-T78 Other and unspecified effects of external causes	0.703	0.297
S99 Other and unspecified injuries of ankle and foot	0.704	0.296
S95 Injury of blood vessels at ankle and foot level	0.705	0.295
S94 Injury of nerves at ankle and foot level	0.705	0.295
S65 Injury of blood vessels at wrist and hand level	0.706	0.294
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.707	0.293
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.707	0.293
S62.2 Fracture of first metacarpal bone	0.707	0.292
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.708	0.292
S60.1 Contusion of finger(s) with damage to nail	0.711	0.289
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.711	0.289
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.712	0.288
S67 Crushing injury of wrist and hand	0.712	0.288
S64.9 Injury of unspecified nerve at wrist and hand level	0.713	0.287
S64.8 Injury of other nerves at wrist and hand level	0.713	0.287
T17 Foreign body in respiratory tract	0.714	0.286
S62.8 Fracture of other and unspecified parts of wrist and hand	0.715	0.285
T87.2 Complications of other reattached body part	0.716	0.284
T87.1 Complications of reattached (part of) lower extremity	0.716	0.284
T87.0 Complications of reattached (part of) upper extremity	0.716	0.284
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.717	0.283
T00.0 Superficial injuries involving head with neck	0.717	0.283
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.718	0.282
S91.2 Open wound of toe(s) with damage to nail	0.722	0.278
T20-T25 Burns and corrosions of external body surface, specified by site	0.722	0.278
S27 Injury of other and unspecified intrathoracic organs	0.722	0.278
T86.1 Kidney transplant failure and rejection	0.724	0.276
T87.3 Neuroma of amputation stump	0.726	0.274
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.726	0.274
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.729	0.271
S92.30 Fracture of metatarsal bone (closed)	0.729	0.271
T01.8 Open wounds involving other combinations of body regions	0.729	0.271
S96.8 Injury of other muscles and tendons at ankle and foot level	0.730	0.270
T87.5 Necrosis of amputation stump	0.730	0.269
S97 Crushing injury of ankle and foot	0.730	0.269
S68.0 Traumatic amputation of thumb (complete)(partial)	0.730	0.269
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.731	0.269
S62.7 Multiple fractures of fingers	0.731	0.269
S91.3 Open wound of other parts of foot	0.732	0.268
T59 Toxic effect of other gases, fumes and vapours	0.732	0.267
T02.8 Fractures involving other combinations of body regions	0.734	0.266
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.734	0.266
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.734	0.266
T02.4 Fractures involving multiple regions of both upper limbs	0.734	0.265
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.736	0.264
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.736	0.264
T88.9 Complication of surgical and medical care, unspecified	0.738	0.262
T29 Burns and corrosions of multiple body regions	0.738	0.262
S98.1 Traumatic amputation of one toe	0.742	0.258
T19.0 Foreign body in urethra	0.742	0.258
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.742	0.258
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.742	0.258
T15.0 Foreign body in cornea	0.743	0.257
T85.2 Mechanical complication of intraocular lens	0.743	0.257
T19.2 Foreign body in vulva and vagina	0.743	0.256
S92.2 Fracture of other tarsal bone(s)	0.745	0.255
T51 Toxic effect of alcohol	0.746	0.254
S62.1 Fracture of other carpal bone(s)	0.747	0.253
T26 Burn and corrosion confined to eye and adnexa	0.747	0.252
T30 Burn and corrosion, body region unspecified	0.748	0.252
T63 Toxic effect of contact with venomous animals	0.749	0.251
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.749	0.250
S92.5 Fracture of other toe	0.749	0.250
T28 Burn and corrosion of other internal organs	0.750	0.250
T27 Burn and corrosion of respiratory tract	0.750	0.250
S92.9 Fracture of foot, unspecified	0.750	0.250
S62.61 Fracture of other finger (open)	0.751	0.249
T01.3 Open wounds involving multiple regions of lower limb(s)	0.751	0.249
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.751	0.249
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.751	0.249
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.751	0.249
T82.4 Mechanical complication of vascular dialysis catheter	0.751	0.248
S69.7 Multiple injuries of wrist and hand	0.752	0.248
T35 Frostbite involving multiple body regions and unspecified frostbite	0.752	0.248
T34 Frostbite with tissue necrosis	0.752	0.248
T33 Superficial frostbite	0.752	0.248
T54 Toxic effect of corrosive substances	0.753	0.247
T19.9 Foreign body in genito-urinary tract, part unspecified	0.753	0.247
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.753	0.247
T19.3 Foreign body in uterus [any part]	0.753	0.247
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.753	0.247
T32 Corrosions classified according to extent of body surface involved	0.753	0.246
S62.60 Fracture of other finger (closed)	0.754	0.246
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.754	0.245
T01.9 Multiple open wounds, unspecified	0.754	0.245
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.754	0.245
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.754	0.245
T01.0 Open wounds involving head with neck	0.754	0.245
T02.9 Multiple fractures, unspecified	0.754	0.245
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.754	0.245
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.754	0.245
T02.3 Fractures involving multiple regions of one lower limb	0.754	0.245
T02.1 Fractures involving thorax with lower back and pelvis	0.754	0.245
T02.0 Fractures involving head with neck	0.754	0.245
S62.4 Multiple fractures of metacarpal bones	0.755	0.245
T88.7 Unspecified adverse effect of drug or medicament	0.755	0.245
S62.0 Fracture of navicular [scaphoid] bone of hand	0.755	0.245
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.756	0.243
T01.2 Open wounds involving multiple regions of upper limb(s)	0.756	0.243
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.757	0.243
T60 Toxic effect of pesticides	0.758	0.242
T57 Toxic effect of other inorganic substances	0.758	0.242
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.758	0.242
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.758	0.242
T15.8 Foreign body in other and multiple parts of external eye	0.758	0.241
T02.5 Fractures involving multiple regions of both lower limbs	0.759	0.241
T25 Burn and corrosion of ankle and foot	0.760	0.240
T83.1 Mechanical complication of other urinary devices and implants	0.761	0.239
S10-S19 Injuries to the neck	0.761	0.239
T88.3 Malignant hyperthermia due to anaesthesis	0.762	0.238
S27.1 Traumatic haemothorax	0.762	0.238
T61 Toxic effect of noxious substances eaten as seafood	0.762	0.238
S92.7 Multiple fractures of foot	0.762	0.238
T52 Toxic effect of organic solvents	0.762	0.238
T70 Effects of air pressure and water pressure	0.762	0.238
S92.4 Fracture of great toe	0.763	0.237
T56 Toxic effect of metals	0.763	0.237
T31 Burns classified according to extent of body surface involved	0.763	0.237
S50-S59 Injuries to the elbow and forearm	0.763	0.237
T68 Hypothermia	0.764	0.236
T55 Toxic effect of soaps and detergents	0.764	0.236
S90 Superficial injury of ankle and foot	0.764	0.235
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.764	0.235
S68.8 Traumatic amputation of other parts of wrist and hand	0.764	0.235
S68.4 Traumatic amputation of hand at wrist level	0.764	0.235
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.764	0.235
T62 Toxic effect of other noxious substances eaten as food	0.764	0.235
S92.1 Fracture of talus	0.765	0.235
T88.1 Other complications following immunisation, not elsewhere classified	0.765	0.235
T88.0 Infection following immunisation	0.765	0.235
S27.2 Traumatic heamopneumothorax	0.765	0.235
T15.1 Foreign body in conjunctival sac	0.766	0.234
T02.2 Fractures involving multiple regions of one upper limb	0.766	0.234
S91.7 Multiple open wounds of ankle and foot	0.766	0.233
S62.20 Fracture of first metacarpal bone (closed)	0.767	0.233
S69.8 Other specified injuries of wrist and hand	0.768	0.232
S98.4 Traumatic amputation of foot, level unspecified	0.769	0.231
S98.3 Traumatic amputation of other parts of foot	0.769	0.231
S98.2 Traumatic amputation of two or more toes	0.769	0.231
S98.0 Traumatic amputation of foot at ankle level	0.769	0.231
T66 Unspecified effects of radiation	0.770	0.229
T58 Toxic effect of carbon monoxide	0.772	0.228
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.772	0.227
T19.1 Foreign body in bladder	0.773	0.227
T03.9 Multiple dislocations, sprains and strains, unspecified	0.773	0.226
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.773	0.226
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.773	0.226
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.773	0.226
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.773	0.226
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.773	0.226
T03.0 Dislocations, sprains and strains involving head with neck	0.773	0.226
T04.9 Multiple crushing injuries, unspecified	0.773	0.226
T04.8 Crushing injuries involving other combinations of body regions	0.773	0.226
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.773	0.226
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.773	0.226
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.773	0.226
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.773	0.226
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.773	0.226
T04.0 Crushing injuries involving head with neck	0.773	0.226
T05.9 Multiple traumatic amputations, unspecified	0.773	0.226
T05.8 Traumatic amputations involving other combinations of body regions	0.773	0.226
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.773	0.226
T05.5 Traumatic amputation of both legs [any level]	0.773	0.226
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.773	0.226
T05.3 Traumatic amputation of both feet	0.773	0.226
T05.2 Traumatic amputation of both arms [any level]	0.773	0.226
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.773	0.226
T05.0 Traumatic amputation of both hands	0.773	0.226
S69.9 Unspecified injury of wrist and hand	0.773	0.226
T88.5 Other complications of anaesthesia	0.774	0.226
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.775	0.225
T15.9 Foreign body on external eye, unspecified	0.775	0.224
T59.9 Gases, fumes and vapours, unspecified	0.775	0.225
T17.2 Foreign body in pharynx	0.775	0.224
T82.0 Mechanical complication of heart valve prosthesis	0.776	0.224
S26 Injury of heart	0.777	0.223
S27.3 Other injuries of lung	0.778	0.222
T06.8 Other specified injuries involving multiple body regions	0.779	0.221
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.779	0.221
T06.3 Injuries of blood vessels involving multiple body regions	0.779	0.221
T06.2 Injuries of nerves involving multiple body regions	0.779	0.221
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.779	0.221
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.779	0.221
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.779	0.221
S25 Injury of blood vessels of thorax	0.779	0.221
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.780	0.219
S65.0 Injury of ulnar artery at wrist and hand level	0.782	0.217
S91.1 Open wound of toe(s) without damage to nail	0.782	0.217
T80.2 Infections following infusion, transfusion and therapeutic injection	0.783	0.217
T51.0 Ethanol	0.783	0.216
S65.4 Injury of blood vessel(s) of thumb	0.784	0.216
T17.3 Foreign body in larynx	0.784	0.215
S92.31 Fracture of metatarsal bone (open)	0.785	0.215
T79 Certain early complications of trauma, not elsewhere classified	0.785	0.215
S99.9 Unspecified injury of ankle and foot	0.786	0.214
T65 Toxic effect of other and unspecified substances	0.786	0.214
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.787	0.213
T06.4 Injuries of muscles and tendons involving multiple body regions	0.787	0.213
T74 Maltreatment syndromes	0.787	0.213
T73 Effects of other deprivation	0.787	0.213
T69 Other effects of reduced temperature	0.787	0.213
T67 Effects of heat and light	0.787	0.213
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.787	0.213
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.787	0.213
S99.7 Multiple injuries of ankle and foot	0.788	0.212
T02.80 Fractures involving other combinations of body regions (closed)	0.788	0.212
S94.9 Injury of unspecified nerve at ankle and foot level	0.788	0.211
S94.8 Injury of other nerves at ankle and foot level	0.788	0.211
S94.7 Injury of multiple nerves at ankle and foot level	0.788	0.211
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.788	0.211
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.788	0.211
S94.1 Injury of medial plantar nerve	0.788	0.211
S94.0 Injury of lateral plantar nerve	0.788	0.211
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.788	0.211
S95.8 Injury of other blood vessels at ankle and foot level	0.788	0.211
S95.7 Injury of multiple blood vessels at ankle and foot level	0.788	0.211
S95.2 Injury of dorsal vein of foot	0.788	0.211
S95.1 Injury of plantar artery of foot	0.788	0.211
S95.0 Injury of dorsal artery of foot	0.788	0.211
S20 Superficial injury of thorax	0.789	0.211
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.789	0.211
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.789	0.211
S65.8 Injury of other blood vessels at wrist and hand level	0.789	0.211
S65.7 Injury of multiple blood vessels at wrist and hand level	0.789	0.211
S65.3 Injury of deep palmar arch	0.789	0.211
S65.2 Injury of superficial palmar arch	0.789	0.211
S99.8 Other specified injuries of ankle and foot	0.789	0.211
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.789	0.211
S92.0 Fracture of calcaneus	0.790	0.210
S62.31 Fracture of other metacarpal bone (open)	0.790	0.210
S62.21 Fracture of first metacarpal bone (open)	0.790	0.210
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.790	0.210
S64.4 Injury of digital nerve of other finger	0.791	0.209
S24 Injury of nerves and spinal cord at thorax level	0.794	0.205
T17.4 Foreign body in trachea	0.795	0.205
T17.1 Foreign body in nostril	0.795	0.205
T17.0 Foreign body in nasal sinus	0.795	0.205
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.796	0.204
S65.5 Injury of blood vessel(s) of other finger	0.797	0.203
T25.2 Burn of second degree of ankle and foot	0.797	0.203
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.798	0.202
S93.0 Dislocation of ankle joint	0.799	0.201
S27.8 Injury of other specified intrathoracic organs	0.799	0.200
S80-S89 Injuries to the knee and lower leg	0.800	0.200
T63.4 Venom of other arthropods	0.800	0.199
S27.9 Injury of unspecified intrathoracic organ	0.801	0.199
S27.7 Multiple injuries of intrathoracic organs	0.801	0.199
S27.6 Injury of pleura	0.801	0.199
S27.5 Injury of thoracic trachea	0.801	0.199
S27.4 Injury of bronchus	0.801	0.199
T75 Effects of other external causes	0.801	0.199
S92.50 Fracture of other toe (closed)	0.802	0.198
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.802	0.198

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations