TreeWAS – Variant ID: rs470530

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.093	0.907
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.101	0.899
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.104	0.896
T50.9 Other and unspecified drugs, medicaments and biological substances	0.114	0.886
T43.2 Other and unspecified antidepressants	0.126	0.874
T46 Poisoning by agents primarily affecting the cardiovascular system	0.168	0.832
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.213	0.787
T46.4 Angiotensin-converting-enzyme inhibitors	0.219	0.781
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.221	0.779
T43.0 Tricyclic and tetracyclic antidepressants	0.235	0.765
T43.5 Other and unspecified antipsychotics and neuroleptics	0.252	0.748
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.260	0.740
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.271	0.729
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.287	0.713
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.292	0.708
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.293	0.707
T50.6 Antidotes and chelating agents, not elsewhere classified	0.294	0.705
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.299	0.701
T43.4 Butyrophenone and thioxanthene neuroleptics	0.308	0.692
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.324	0.675
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.327	0.673
T50.1 Loop [high-ceiling] diuretics	0.329	0.671
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.337	0.663
T47.1 Other antacids and anti-gastric-secretion drugs	0.338	0.662
T43.6 Psychostimulants with abuse potential	0.346	0.654
T43.8 Other psychotropic drugs, not elsewhere classified	0.356	0.644
T50.7 Analeptics and opioid receptor antagonists	0.358	0.642
T50.5 Appetite depressants	0.358	0.642
T50.3 Electrolytic, caloric and water-balance agents	0.358	0.642
T50.0 Mineralocorticoids and their antagonists	0.358	0.642
T42.3 Barbiturates	0.360	0.640
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.360	0.640
T50.4 Drugs affecting uric acid metabolism	0.364	0.636
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.366	0.634
T46.3 Coronary vasodilators, not elsewhere classified	0.369	0.631
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.377	0.623
T41 Poisoning by anaesthetics and therapeutic gases	0.378	0.622
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.381	0.619
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.384	0.616
T50.8 Diagnostic agents	0.392	0.608
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.392	0.608
T43.3 Phenothiazine antipsychotics and neuroleptics	0.400	0.600
T36 Poisoning by systemic antibiotics	0.401	0.599
T46.8 Antivaricose drugs, including sclerosing agents	0.404	0.596
T46.7 Peripheral vasodilators	0.404	0.596
T40.2 Other opioids	0.408	0.592
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.414	0.586
T43.9 Psychotropic drug, unspecified	0.414	0.586
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.417	0.583
T42.0 Hydantoin derivatives	0.418	0.582
T40.5 Cocaine	0.419	0.581
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.424	0.576
T46.5 Other antihypertensive drugs, not elsewhere classified	0.425	0.575
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.425	0.575
T46.1 Calcium-channel blockers	0.428	0.572
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.432	0.568
T45.2 Vitamins, not elsewhere classified	0.434	0.566
T42.5 Mixed antiepileptics, not elsewhere classified	0.436	0.564
T42.2 Succinimides and oxazolidinediones	0.436	0.564
T42.4 Benzodiazepines	0.439	0.561
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.440	0.560
T40.1 Heroin	0.441	0.559
T39.4 Antirheumatics, not elsewhere classified	0.441	0.559
T39.2 Pyrazolone derivatives	0.441	0.559
T45.0 Antiallergic and antiemetic drugs	0.444	0.556
T38.0 Glucocorticoids and synthetic analogues	0.452	0.548
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.453	0.547
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.454	0.546
T15-T19 Effects of foreign body entering through natural orifice	0.459	0.541
T45.1 Antineoplastic and immunosuppressive drugs	0.460	0.540
T18 Foreign body in alimentary tract	0.461	0.539
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.463	0.537
T18.1 Foreign body in oesophagus	0.465	0.535
T47.0 Histamine H(2)-receptor antagonists	0.468	0.532
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.469	0.531
T47.8 Other agents primarily affecting the gastro-intestinal system	0.469	0.531
T47.7 Emetics	0.469	0.531
T47.5 Digestants	0.469	0.531
T47.3 Saline and osmotic laxatives	0.469	0.531
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.477	0.523
T45.9 Primarily systemic and haematological agent, unspecified	0.477	0.522
T45.8 Other primarily systemic and haematological agents	0.477	0.522
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.477	0.522
T45.6 Fibrinolysis-affecting drugs	0.477	0.522
T45.4 Iron and its compounds	0.477	0.522
T45.3 Enzymes, not elsewhere classified	0.477	0.522
T39.0 Salicylates	0.483	0.516
T38.5 Other oestrogens and progestogens	0.484	0.516
T47.4 Other laxatives	0.484	0.516
T45.5 Anticoagulants	0.484	0.515
T38.8 Other and unspecified hormones and their synthetic substitutes	0.487	0.513
T48.5 Anti-common-cold drugs	0.487	0.513
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.491	0.509
T38.1 Thyroid hormones and substitutes	0.492	0.508
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.492	0.508
T40.8 Lysergide [LSD]	0.492	0.508
T40.7 Cannabis (derivatives)	0.492	0.508
T40.0 Opium	0.492	0.508
S60-S69 Injuries to the wrist and hand	0.493	0.507
T38.9 Other and unspecified hormone antagonists	0.493	0.507
T38.7 Androgens and anabolic congeners	0.493	0.507
T38.4 Oral contraceptives	0.493	0.507
T38.2 Antithyroid drugs	0.493	0.507
T47.6 Antidiarrhoeal drugs	0.494	0.506
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.499	0.501
T00-T07 Injuries involving multiple body regions	0.500	0.500
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.501	0.499
T42.1 Iminostilbenes	0.504	0.495
S60 Superficial injury of wrist and hand	0.508	0.492
T40.3 Methadone	0.511	0.489
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.511	0.489
T85 Complications of other internal prosthetic devices, implants and grafts	0.512	0.488
T49.9 Topical agent, unspecified	0.516	0.484
T49.8 Other topical agents	0.516	0.484
T49.7 Dental drugs, topically applied	0.516	0.484
T49.6 Otorhinolaryngological drugs and preparations	0.516	0.484
T49.5 Ophthalmological drugs and preparations	0.516	0.484
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.516	0.484
T49.3 Emollients, demulcents and protectants	0.516	0.484
T49.2 Local astringents and local detergents	0.516	0.484
T49.1 Antipruritics	0.516	0.484
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.517	0.483
T48.4 Expectorants	0.517	0.483
T48.3 Antitussives	0.517	0.483
T48.2 Other and unspecified agents primarily acting on muscles	0.517	0.483
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.517	0.483
T48.0 Oxytocic drugs	0.517	0.483
T86 Failure and rejection of transplanted organs and tissues	0.522	0.478
T80 Complications following infusion, transfusion and therapeutic injection	0.524	0.476
T39.1 4-Aminophenol derivatives	0.524	0.476
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.524	0.476
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.524	0.476
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.524	0.476
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.524	0.476
T44.1 Other parasympathomimetics [cholinergics]	0.524	0.476
T44.0 Anticholinesterase agents	0.524	0.476
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.526	0.474
T48.6 Antiasthmatics, not elsewhere classified	0.526	0.474
T47.2 Stimulant laxatives	0.527	0.472
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.527	0.472
S90-S99 Injuries to the ankle and foot	0.533	0.467
S60.9 Superficial injury of wrist and hand, unspecified	0.538	0.462
S64 Injury of nerves at wrist and hand level	0.541	0.459
T87 Complications peculiar to reattachment and amputation	0.549	0.451
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.550	0.450
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.551	0.449
T00 Superficial injuries involving multiple body regions	0.552	0.448
T41.5 Therapeutic gases	0.554	0.446
T41.4 Anaesthetic, unspecified	0.554	0.446
T41.3 Local anaesthetics	0.554	0.446
T41.1 Intravenous anaesthetics	0.554	0.446
T41.0 Inhaled anaesthetics	0.554	0.446
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.556	0.444
T37.5 Antiviral drugs	0.556	0.444
T37.4 Anthelminthics	0.556	0.444
T37.3 Other antiprotozoal drugs	0.556	0.444
T37.1 Antimycobacterial drugs	0.556	0.444
T37.0 Sulphonamides	0.556	0.444
T36.4 Tetracyclines	0.560	0.440
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.561	0.438
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.563	0.437
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.565	0.435
T36.3 Macrolides	0.565	0.435
T18.0 Foreign body in mouth	0.565	0.435
T36.9 Systemic antibiotic, unspecified	0.570	0.429
T36.7 Antifungal antibiotics, systemically used	0.570	0.429
T36.6 Rifamycins	0.570	0.429
T36.5 Aminoglycosides	0.570	0.429
T36.2 Chloramphenicol group	0.570	0.429
T37.8 Other specified systemic anti-infectives and antiparasitics	0.571	0.429
T37.2 Antimalarials and drugs acting on other blood protozoa	0.571	0.429
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.574	0.426
T41.2 Other and unspecified general anaesthetics	0.583	0.417
T16 Foreign body in ear	0.583	0.417
T18.9 Foreign body in alimentary tract, part unspecified	0.584	0.416
T40.6 Other and unspecified narcotics	0.584	0.415
T36.8 Other systemic antibiotics	0.586	0.414
S62 Fracture at wrist and hand level	0.588	0.412
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.591	0.409
T36.0 Penicillins	0.593	0.407
S64.1 Injury of median nerve at wrist and hand level	0.595	0.405
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.597	0.403
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.599	0.401
S60.2 Contusion of other parts of wrist and hand	0.599	0.401
T18.3 Foreign body in small intestine	0.600	0.400
T83.2 Mechanical complication of graft of urinary organ	0.601	0.399
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.601	0.399
S60.7 Multiple superficial injuries of wrist and hand	0.602	0.398
T86.8 Failure and rejection of other transplanted organs and tissues	0.602	0.398
S64.0 Injury of ulnar nerve at wrist and hand level	0.604	0.396
T26-T28 Burns and corrosions confined to eye and internal organs	0.605	0.395
S96 Injury of muscle and tendon at ankle and foot level	0.605	0.395
T18.5 Foreign body in anus and rectum	0.606	0.394
T33-T35 Frostbite	0.608	0.392
T86.0 Bone-marrow transplant rejection	0.608	0.391
T19 Foreign body in genito-urinary tract	0.609	0.391
S60.0 Contusion of finger(s) without damage to nail	0.610	0.390
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.610	0.390
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.611	0.389
T02 Fractures involving multiple body regions	0.611	0.389
T01 Open wounds involving multiple body regions	0.611	0.389
T83.0 Mechanical complication of urinary (indwelling) catheter	0.613	0.387
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.613	0.387
T18.8 Foreign body in other and multiple parts of alimentary tract	0.613	0.387
T18.4 Foreign body in colon	0.613	0.387
S92 Fracture of foot, except ankle	0.614	0.386
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.615	0.385
S64.3 Injury of digital nerve of thumb	0.615	0.385
T83.3 Mechanical complication of intra-uterine contraceptive device	0.616	0.384
S66 Injury of muscle and tendon at wrist and hand level	0.617	0.383
T15 Foreign body on external eye	0.618	0.382
T40.4 Other synthetic narcotics	0.620	0.380
T00.9 Multiple superficial injuries, unspecified	0.620	0.380
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.621	0.379
T87.6 Other and unspecified complications of amputation stump	0.625	0.375
S68 Traumatic amputation of wrist and hand	0.625	0.375
S62.3 Fracture of other metacarpal bone	0.627	0.373
T79-T79 Certain early complications of trauma	0.627	0.372
S69 Other and unspecified injuries of wrist and hand	0.628	0.372
S91 Open wound of ankle and foot	0.629	0.371
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.632	0.368
T18.2 Foreign body in stomach	0.632	0.367
S98 Traumatic amputation of ankle and foot	0.634	0.366
T88 Other complications of surgical and medical care, not elsewhere classified	0.635	0.365
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.639	0.361
T05 Traumatic amputations involving multiple body regions	0.641	0.358
T04 Crushing injuries involving multiple body regions	0.641	0.358
T03 Dislocations, sprains and strains involving multiple body regions	0.641	0.358
T07 Unspecified multiple injuries	0.641	0.358
T87.4 Infection of amputation stump	0.642	0.358
T00.8 Superficial injuries involving other combinations of body regions	0.645	0.354
S60.8 Other superficial injuries of wrist and hand	0.646	0.354
S62.30 Fracture of other metacarpal bone (closed)	0.648	0.352
S64.7 Injury of multiple nerves at wrist and hand level	0.648	0.352
T06 Other injuries involving multiple body regions, not elsewhere classified	0.650	0.350
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.651	0.349
S20-S29 Injuries to the thorax	0.653	0.347
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.653	0.347
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.654	0.346
T86.4 Liver transplant failure and rejection	0.656	0.344
T86.3 Heart-lung transplant failure and rejection	0.657	0.343
T86.2 Heart transplant failure and rejection	0.657	0.343
S92.3 Fracture of metatarsal bone	0.658	0.342
T80.6 Other serum reactions	0.658	0.341
T80.5 Anaphylactic shock due to serum	0.658	0.341
T80.4 Rh incompatibility reaction	0.658	0.341
T80.3 ABO incompatibility reaction	0.658	0.341
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.658	0.341
T66-T78 Other and unspecified effects of external causes	0.661	0.339
S99 Other and unspecified injuries of ankle and foot	0.663	0.337
S65 Injury of blood vessels at wrist and hand level	0.665	0.335
S95 Injury of blood vessels at ankle and foot level	0.665	0.335
S94 Injury of nerves at ankle and foot level	0.665	0.335
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.667	0.333
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.667	0.333
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.668	0.332
S64.9 Injury of unspecified nerve at wrist and hand level	0.671	0.329
S64.8 Injury of other nerves at wrist and hand level	0.671	0.329
S60.1 Contusion of finger(s) with damage to nail	0.672	0.328
S67 Crushing injury of wrist and hand	0.672	0.328
T17 Foreign body in respiratory tract	0.672	0.327
T87.2 Complications of other reattached body part	0.676	0.323
T87.1 Complications of reattached (part of) lower extremity	0.676	0.323
T87.0 Complications of reattached (part of) upper extremity	0.676	0.323
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.678	0.322
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.678	0.322
T00.0 Superficial injuries involving head with neck	0.678	0.322
S62.2 Fracture of first metacarpal bone	0.678	0.321
S62.6 Fracture of other finger	0.680	0.320
S91.2 Open wound of toe(s) with damage to nail	0.683	0.317
T86.1 Kidney transplant failure and rejection	0.684	0.316
S27 Injury of other and unspecified intrathoracic organs	0.686	0.314
T87.3 Neuroma of amputation stump	0.687	0.313
S62.8 Fracture of other and unspecified parts of wrist and hand	0.687	0.313
T20-T25 Burns and corrosions of external body surface, specified by site	0.687	0.313
S92.30 Fracture of metatarsal bone (closed)	0.690	0.310
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.691	0.309
T01.8 Open wounds involving other combinations of body regions	0.692	0.308
S68.0 Traumatic amputation of thumb (complete)(partial)	0.692	0.308
T87.5 Necrosis of amputation stump	0.692	0.307
S96.8 Injury of other muscles and tendons at ankle and foot level	0.693	0.307
T59 Toxic effect of other gases, fumes and vapours	0.693	0.307
S91.3 Open wound of other parts of foot	0.693	0.307
S97 Crushing injury of ankle and foot	0.694	0.306
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.694	0.305
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.696	0.304
T02.8 Fractures involving other combinations of body regions	0.697	0.303
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.697	0.302
T02.4 Fractures involving multiple regions of both upper limbs	0.698	0.302
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.698	0.302
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.698	0.302
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.700	0.300
T85.2 Mechanical complication of intraocular lens	0.702	0.298
S62.7 Multiple fractures of fingers	0.705	0.295
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.705	0.295
T82.4 Mechanical complication of vascular dialysis catheter	0.705	0.295
S98.1 Traumatic amputation of one toe	0.706	0.293
T29 Burns and corrosions of multiple body regions	0.707	0.293
T19.0 Foreign body in urethra	0.707	0.293
T88.9 Complication of surgical and medical care, unspecified	0.707	0.293
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.707	0.293
T51 Toxic effect of alcohol	0.707	0.293
T15.0 Foreign body in cornea	0.708	0.292
T19.2 Foreign body in vulva and vagina	0.709	0.291
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.709	0.291
S92.2 Fracture of other tarsal bone(s)	0.710	0.290
T63 Toxic effect of contact with venomous animals	0.712	0.288
T26 Burn and corrosion confined to eye and adnexa	0.713	0.286
S92.5 Fracture of other toe	0.715	0.285
S92.9 Fracture of foot, unspecified	0.716	0.284
T28 Burn and corrosion of other internal organs	0.716	0.283
T27 Burn and corrosion of respiratory tract	0.716	0.283
T54 Toxic effect of corrosive substances	0.717	0.283
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.717	0.283
T01.3 Open wounds involving multiple regions of lower limb(s)	0.717	0.283
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.717	0.283
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.717	0.283
S69.7 Multiple injuries of wrist and hand	0.717	0.283
T30 Burn and corrosion, body region unspecified	0.717	0.282
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.718	0.282
T35 Frostbite involving multiple body regions and unspecified frostbite	0.719	0.281
T34 Frostbite with tissue necrosis	0.719	0.281
T33 Superficial frostbite	0.719	0.281
T19.9 Foreign body in genito-urinary tract, part unspecified	0.719	0.281
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.719	0.281
T19.3 Foreign body in uterus [any part]	0.719	0.281
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.720	0.280
T02.9 Multiple fractures, unspecified	0.721	0.279
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.721	0.279
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.721	0.279
T02.3 Fractures involving multiple regions of one lower limb	0.721	0.279
T02.1 Fractures involving thorax with lower back and pelvis	0.721	0.279
T02.0 Fractures involving head with neck	0.721	0.279
T01.9 Multiple open wounds, unspecified	0.721	0.279
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.721	0.279
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.721	0.279
T01.0 Open wounds involving head with neck	0.721	0.279
S62.1 Fracture of other carpal bone(s)	0.722	0.277
T60 Toxic effect of pesticides	0.722	0.277
T57 Toxic effect of other inorganic substances	0.722	0.277
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.722	0.277
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.722	0.277
T01.2 Open wounds involving multiple regions of upper limb(s)	0.723	0.277
T32 Corrosions classified according to extent of body surface involved	0.724	0.276
T88.7 Unspecified adverse effect of drug or medicament	0.725	0.275
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.725	0.275
T83.1 Mechanical complication of other urinary devices and implants	0.726	0.274
T15.8 Foreign body in other and multiple parts of external eye	0.726	0.274
T02.5 Fractures involving multiple regions of both lower limbs	0.726	0.274
T61 Toxic effect of noxious substances eaten as seafood	0.727	0.273
T52 Toxic effect of organic solvents	0.727	0.272
T56 Toxic effect of metals	0.728	0.272
S50-S59 Injuries to the elbow and forearm	0.729	0.271
T70 Effects of air pressure and water pressure	0.729	0.271
S92.7 Multiple fractures of foot	0.729	0.271
T55 Toxic effect of soaps and detergents	0.729	0.271
S92.4 Fracture of great toe	0.730	0.270
T68 Hypothermia	0.730	0.270
T25 Burn and corrosion of ankle and foot	0.730	0.270
T62 Toxic effect of other noxious substances eaten as food	0.730	0.270
S62.4 Multiple fractures of metacarpal bones	0.730	0.269
S27.1 Traumatic haemothorax	0.730	0.269
S90 Superficial injury of ankle and foot	0.731	0.269
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.731	0.269
S62.0 Fracture of navicular [scaphoid] bone of hand	0.731	0.269
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.731	0.269
S68.8 Traumatic amputation of other parts of wrist and hand	0.731	0.269
S68.4 Traumatic amputation of hand at wrist level	0.731	0.269
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.731	0.269
S92.1 Fracture of talus	0.732	0.268
S10-S19 Injuries to the neck	0.733	0.267
S91.7 Multiple open wounds of ankle and foot	0.734	0.266
T02.2 Fractures involving multiple regions of one upper limb	0.734	0.266
T88.3 Malignant hyperthermia due to anaesthesis	0.734	0.266
T15.1 Foreign body in conjunctival sac	0.734	0.266
T82.0 Mechanical complication of heart valve prosthesis	0.734	0.266
S27.2 Traumatic heamopneumothorax	0.734	0.266
S69.8 Other specified injuries of wrist and hand	0.736	0.264
S98.4 Traumatic amputation of foot, level unspecified	0.737	0.262
S98.3 Traumatic amputation of other parts of foot	0.737	0.262
S98.2 Traumatic amputation of two or more toes	0.737	0.262
S98.0 Traumatic amputation of foot at ankle level	0.737	0.262
T88.1 Other complications following immunisation, not elsewhere classified	0.738	0.262
T88.0 Infection following immunisation	0.738	0.262
T58 Toxic effect of carbon monoxide	0.738	0.262
T66 Unspecified effects of radiation	0.738	0.262
T31 Burns classified according to extent of body surface involved	0.740	0.260
S69.9 Unspecified injury of wrist and hand	0.741	0.259
T17.2 Foreign body in pharynx	0.742	0.258
T59.9 Gases, fumes and vapours, unspecified	0.742	0.258
T19.1 Foreign body in bladder	0.742	0.257
T03.9 Multiple dislocations, sprains and strains, unspecified	0.743	0.257
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.743	0.257
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.743	0.257
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.743	0.257
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.743	0.257
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.743	0.257
T03.0 Dislocations, sprains and strains involving head with neck	0.743	0.257
T04.9 Multiple crushing injuries, unspecified	0.743	0.257
T04.8 Crushing injuries involving other combinations of body regions	0.743	0.257
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.743	0.257
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.743	0.257
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.743	0.257
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.743	0.257
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.743	0.257
T04.0 Crushing injuries involving head with neck	0.743	0.257
T05.9 Multiple traumatic amputations, unspecified	0.743	0.257
T05.8 Traumatic amputations involving other combinations of body regions	0.743	0.257
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.743	0.257
T05.5 Traumatic amputation of both legs [any level]	0.743	0.257
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.743	0.257
T05.3 Traumatic amputation of both feet	0.743	0.257
T05.2 Traumatic amputation of both arms [any level]	0.743	0.257
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.743	0.257
T05.0 Traumatic amputation of both hands	0.743	0.257
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.743	0.257
S62.20 Fracture of first metacarpal bone (closed)	0.743	0.257
T15.9 Foreign body on external eye, unspecified	0.745	0.255
S64.4 Injury of digital nerve of other finger	0.745	0.255
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.747	0.253
T88.5 Other complications of anaesthesia	0.747	0.252
T51.0 Ethanol	0.748	0.252
S26 Injury of heart	0.749	0.251
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.749	0.251
S27.3 Other injuries of lung	0.749	0.251
T06.8 Other specified injuries involving multiple body regions	0.749	0.251
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.749	0.251
T06.3 Injuries of blood vessels involving multiple body regions	0.749	0.251
T06.2 Injuries of nerves involving multiple body regions	0.749	0.251
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.749	0.251
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.749	0.251
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.751	0.249
S25 Injury of blood vessels of thorax	0.751	0.249
S91.1 Open wound of toe(s) without damage to nail	0.751	0.248
S65.0 Injury of ulnar artery at wrist and hand level	0.752	0.248
T79 Certain early complications of trauma, not elsewhere classified	0.752	0.248
T17.3 Foreign body in larynx	0.753	0.246
S65.4 Injury of blood vessel(s) of thumb	0.754	0.246
S92.31 Fracture of metatarsal bone (open)	0.755	0.245
T65 Toxic effect of other and unspecified substances	0.755	0.245
S99.9 Unspecified injury of ankle and foot	0.755	0.245
T80.2 Infections following infusion, transfusion and therapeutic injection	0.755	0.244
S62.61 Fracture of other finger (open)	0.757	0.243
T74 Maltreatment syndromes	0.757	0.243
T73 Effects of other deprivation	0.757	0.243
T69 Other effects of reduced temperature	0.757	0.243
T67 Effects of heat and light	0.757	0.243
S62.60 Fracture of other finger (closed)	0.757	0.243
T06.4 Injuries of muscles and tendons involving multiple body regions	0.758	0.242
S99.7 Multiple injuries of ankle and foot	0.758	0.242
T02.80 Fractures involving other combinations of body regions (closed)	0.759	0.241
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.759	0.241
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.759	0.241
S20 Superficial injury of thorax	0.759	0.240
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.760	0.240
S65.8 Injury of other blood vessels at wrist and hand level	0.760	0.240
S65.7 Injury of multiple blood vessels at wrist and hand level	0.760	0.240
S65.3 Injury of deep palmar arch	0.760	0.240
S65.2 Injury of superficial palmar arch	0.760	0.240
S99.8 Other specified injuries of ankle and foot	0.760	0.240
S94.9 Injury of unspecified nerve at ankle and foot level	0.760	0.240
S94.8 Injury of other nerves at ankle and foot level	0.760	0.240
S94.7 Injury of multiple nerves at ankle and foot level	0.760	0.240
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.760	0.240
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.760	0.240
S94.1 Injury of medial plantar nerve	0.760	0.240
S94.0 Injury of lateral plantar nerve	0.760	0.240
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.760	0.240
S95.8 Injury of other blood vessels at ankle and foot level	0.760	0.240
S95.7 Injury of multiple blood vessels at ankle and foot level	0.760	0.240
S95.2 Injury of dorsal vein of foot	0.760	0.240
S95.1 Injury of plantar artery of foot	0.760	0.240
S95.0 Injury of dorsal artery of foot	0.760	0.240
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.760	0.240
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.762	0.237
T17.4 Foreign body in trachea	0.765	0.235
T17.1 Foreign body in nostril	0.765	0.235
T17.0 Foreign body in nasal sinus	0.765	0.235
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.766	0.234
S92.0 Fracture of calcaneus	0.766	0.234
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.767	0.233
S80-S89 Injuries to the knee and lower leg	0.767	0.233
S24 Injury of nerves and spinal cord at thorax level	0.768	0.232
S62.31 Fracture of other metacarpal bone (open)	0.768	0.232
S65.5 Injury of blood vessel(s) of other finger	0.768	0.232
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.769	0.231
S62.21 Fracture of first metacarpal bone (open)	0.769	0.231
T63.4 Venom of other arthropods	0.770	0.229
T25.2 Burn of second degree of ankle and foot	0.771	0.229
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.772	0.228
T75 Effects of other external causes	0.773	0.227
S27.8 Injury of other specified intrathoracic organs	0.773	0.227
T17.5 Foreign body in bronchus	0.774	0.226
S92.50 Fracture of other toe (closed)	0.774	0.226
S27.9 Injury of unspecified intrathoracic organ	0.775	0.225
S27.7 Multiple injuries of intrathoracic organs	0.775	0.225
S27.6 Injury of pleura	0.775	0.225
S27.5 Injury of thoracic trachea	0.775	0.225
S27.4 Injury of bronchus	0.775	0.225
T71 Asphyxiation	0.775	0.225

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations