TreeWAS – Variant ID: rs470928

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.093	0.907
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.099	0.901
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.103	0.897
T50.9 Other and unspecified drugs, medicaments and biological substances	0.111	0.889
T43.2 Other and unspecified antidepressants	0.124	0.876
T46 Poisoning by agents primarily affecting the cardiovascular system	0.163	0.837
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.213	0.787
T46.4 Angiotensin-converting-enzyme inhibitors	0.215	0.785
T43.0 Tricyclic and tetracyclic antidepressants	0.225	0.775
T43.5 Other and unspecified antipsychotics and neuroleptics	0.235	0.765
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.241	0.759
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.243	0.757
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.259	0.741
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.282	0.718
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.286	0.714
T50.6 Antidotes and chelating agents, not elsewhere classified	0.294	0.706
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.304	0.696
T43.4 Butyrophenone and thioxanthene neuroleptics	0.307	0.693
T47.1 Other antacids and anti-gastric-secretion drugs	0.310	0.690
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.324	0.676
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.325	0.675
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.327	0.673
T50.1 Loop [high-ceiling] diuretics	0.328	0.672
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.337	0.663
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.340	0.660
T43.6 Psychostimulants with abuse potential	0.345	0.655
T43.8 Other psychotropic drugs, not elsewhere classified	0.354	0.646
T50.7 Analeptics and opioid receptor antagonists	0.357	0.643
T50.5 Appetite depressants	0.357	0.643
T50.3 Electrolytic, caloric and water-balance agents	0.357	0.643
T50.0 Mineralocorticoids and their antagonists	0.357	0.643
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.357	0.643
T42.3 Barbiturates	0.360	0.640
T50.4 Drugs affecting uric acid metabolism	0.363	0.636
T46.3 Coronary vasodilators, not elsewhere classified	0.366	0.634
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.376	0.623
T41 Poisoning by anaesthetics and therapeutic gases	0.378	0.622
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.381	0.619
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.385	0.615
T50.8 Diagnostic agents	0.391	0.609
T46.8 Antivaricose drugs, including sclerosing agents	0.400	0.600
T46.7 Peripheral vasodilators	0.400	0.600
T36 Poisoning by systemic antibiotics	0.403	0.597
T43.3 Phenothiazine antipsychotics and neuroleptics	0.403	0.597
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.410	0.590
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.410	0.590
T43.9 Psychotropic drug, unspecified	0.413	0.587
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.417	0.583
T42.0 Hydantoin derivatives	0.419	0.581
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.420	0.579
T46.5 Other antihypertensive drugs, not elsewhere classified	0.421	0.579
T45.2 Vitamins, not elsewhere classified	0.424	0.575
T40.2 Other opioids	0.425	0.575
T46.1 Calcium-channel blockers	0.425	0.574
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.428	0.572
T40.5 Cocaine	0.429	0.571
T45.1 Antineoplastic and immunosuppressive drugs	0.431	0.569
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.431	0.568
T42.5 Mixed antiepileptics, not elsewhere classified	0.436	0.564
T42.2 Succinimides and oxazolidinediones	0.436	0.564
T45.0 Antiallergic and antiemetic drugs	0.437	0.563
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.443	0.557
T38.0 Glucocorticoids and synthetic analogues	0.443	0.556
T40.1 Heroin	0.451	0.549
T42.4 Benzodiazepines	0.452	0.548
T47.0 Histamine H(2)-receptor antagonists	0.454	0.545
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.456	0.544
T47.8 Other agents primarily affecting the gastro-intestinal system	0.456	0.544
T47.7 Emetics	0.456	0.544
T47.5 Digestants	0.456	0.544
T47.3 Saline and osmotic laxatives	0.456	0.544
T39.4 Antirheumatics, not elsewhere classified	0.457	0.543
T39.2 Pyrazolone derivatives	0.457	0.543
T45.9 Primarily systemic and haematological agent, unspecified	0.469	0.531
T45.8 Other primarily systemic and haematological agents	0.469	0.531
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.469	0.531
T45.6 Fibrinolysis-affecting drugs	0.469	0.531
T45.4 Iron and its compounds	0.469	0.531
T45.3 Enzymes, not elsewhere classified	0.469	0.531
T47.4 Other laxatives	0.471	0.528
T38.5 Other oestrogens and progestogens	0.476	0.523
T45.5 Anticoagulants	0.477	0.523
T38.8 Other and unspecified hormones and their synthetic substitutes	0.479	0.521
T47.6 Antidiarrhoeal drugs	0.481	0.518
T38.1 Thyroid hormones and substitutes	0.485	0.515
T38.9 Other and unspecified hormone antagonists	0.485	0.514
T38.7 Androgens and anabolic congeners	0.485	0.514
T38.4 Oral contraceptives	0.485	0.514
T38.2 Antithyroid drugs	0.485	0.514
T48.5 Anti-common-cold drugs	0.487	0.513
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.491	0.509
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.501	0.499
T40.8 Lysergide [LSD]	0.501	0.499
T40.7 Cannabis (derivatives)	0.501	0.499
T40.0 Opium	0.501	0.499
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.501	0.498
T39.0 Salicylates	0.504	0.496
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.504	0.495
T42.1 Iminostilbenes	0.506	0.494
T49.9 Topical agent, unspecified	0.516	0.484
T49.8 Other topical agents	0.516	0.484
T49.7 Dental drugs, topically applied	0.516	0.484
T49.6 Otorhinolaryngological drugs and preparations	0.516	0.484
T49.5 Ophthalmological drugs and preparations	0.516	0.484
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.516	0.484
T49.3 Emollients, demulcents and protectants	0.516	0.484
T49.2 Local astringents and local detergents	0.516	0.484
T49.1 Antipruritics	0.516	0.484
T47.2 Stimulant laxatives	0.516	0.484
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.517	0.482
T48.4 Expectorants	0.517	0.482
T48.3 Antitussives	0.517	0.482
T48.2 Other and unspecified agents primarily acting on muscles	0.517	0.482
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.517	0.482
T48.0 Oxytocic drugs	0.517	0.482
T40.3 Methadone	0.519	0.481
T48.6 Antiasthmatics, not elsewhere classified	0.526	0.473
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.527	0.473
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.527	0.473
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.527	0.473
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.527	0.473
T44.1 Other parasympathomimetics [cholinergics]	0.527	0.473
T44.0 Anticholinesterase agents	0.527	0.473
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.530	0.470
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.535	0.464
T41.5 Therapeutic gases	0.554	0.446
T41.4 Anaesthetic, unspecified	0.554	0.446
T41.3 Local anaesthetics	0.554	0.446
T41.1 Intravenous anaesthetics	0.554	0.446
T41.0 Inhaled anaesthetics	0.554	0.446
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.556	0.443
T37.5 Antiviral drugs	0.556	0.443
T37.4 Anthelminthics	0.556	0.443
T37.3 Other antiprotozoal drugs	0.556	0.443
T37.1 Antimycobacterial drugs	0.556	0.443
T37.0 Sulphonamides	0.556	0.443
T36.4 Tetracyclines	0.561	0.439
T39.1 4-Aminophenol derivatives	0.564	0.436
T36.3 Macrolides	0.566	0.434
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.568	0.432
T36.9 Systemic antibiotic, unspecified	0.571	0.428
T36.7 Antifungal antibiotics, systemically used	0.571	0.428
T36.6 Rifamycins	0.571	0.428
T36.5 Aminoglycosides	0.571	0.428
T36.2 Chloramphenicol group	0.571	0.428
T37.8 Other specified systemic anti-infectives and antiparasitics	0.572	0.428
T37.2 Antimalarials and drugs acting on other blood protozoa	0.572	0.428
T41.2 Other and unspecified general anaesthetics	0.583	0.417
T36.8 Other systemic antibiotics	0.587	0.413
T40.6 Other and unspecified narcotics	0.593	0.407
T36.0 Penicillins	0.595	0.405
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.600	0.400
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.610	0.390
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.612	0.388
T15-T19 Effects of foreign body entering through natural orifice	0.614	0.386
T18 Foreign body in alimentary tract	0.614	0.386
T18.1 Foreign body in oesophagus	0.616	0.384
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.619	0.381
T40.4 Other synthetic narcotics	0.629	0.371
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.629	0.371
S60-S69 Injuries to the wrist and hand	0.639	0.361
T00-T07 Injuries involving multiple body regions	0.644	0.356
S60 Superficial injury of wrist and hand	0.650	0.350
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.653	0.347
T80 Complications following infusion, transfusion and therapeutic injection	0.657	0.343
T85 Complications of other internal prosthetic devices, implants and grafts	0.661	0.339
T86 Failure and rejection of transplanted organs and tissues	0.662	0.338
S90-S99 Injuries to the ankle and foot	0.670	0.330
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.671	0.329
S60.9 Superficial injury of wrist and hand, unspecified	0.672	0.328
S64 Injury of nerves at wrist and hand level	0.675	0.325
T87 Complications peculiar to reattachment and amputation	0.681	0.319
T00 Superficial injuries involving multiple body regions	0.681	0.319
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.687	0.313
T18.0 Foreign body in mouth	0.689	0.311
T16 Foreign body in ear	0.693	0.307
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.698	0.302
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.700	0.300
S62 Fracture at wrist and hand level	0.700	0.300
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.700	0.300
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.703	0.297
T18.9 Foreign body in alimentary tract, part unspecified	0.713	0.287
S64.1 Injury of median nerve at wrist and hand level	0.714	0.286
T18.3 Foreign body in small intestine	0.714	0.286
S60.2 Contusion of other parts of wrist and hand	0.715	0.285
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.716	0.284
T83.2 Mechanical complication of graft of urinary organ	0.717	0.283
S60.7 Multiple superficial injuries of wrist and hand	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.718	0.282
T18.5 Foreign body in anus and rectum	0.718	0.281
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.719	0.281
T86.8 Failure and rejection of other transplanted organs and tissues	0.720	0.280
S64.0 Injury of ulnar nerve at wrist and hand level	0.720	0.280
T33-T35 Frostbite	0.720	0.280
T19 Foreign body in genito-urinary tract	0.721	0.279
S96 Injury of muscle and tendon at ankle and foot level	0.721	0.279
S66 Injury of muscle and tendon at wrist and hand level	0.722	0.278
S60.0 Contusion of finger(s) without damage to nail	0.723	0.277
T01 Open wounds involving multiple body regions	0.723	0.277
T02 Fractures involving multiple body regions	0.723	0.277
T18.8 Foreign body in other and multiple parts of alimentary tract	0.723	0.277
T18.4 Foreign body in colon	0.723	0.277
T86.0 Bone-marrow transplant rejection	0.724	0.276
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.724	0.276
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.727	0.273
T15 Foreign body on external eye	0.727	0.273
S92 Fracture of foot, except ankle	0.728	0.272
S64.3 Injury of digital nerve of thumb	0.728	0.272
T83.3 Mechanical complication of intra-uterine contraceptive device	0.729	0.271
T83.0 Mechanical complication of urinary (indwelling) catheter	0.729	0.271
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.730	0.270
T00.9 Multiple superficial injuries, unspecified	0.730	0.270
S62.3 Fracture of other metacarpal bone	0.730	0.270
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.734	0.266
T87.6 Other and unspecified complications of amputation stump	0.735	0.265
S68 Traumatic amputation of wrist and hand	0.736	0.264
T79-T79 Certain early complications of trauma	0.737	0.263
S69 Other and unspecified injuries of wrist and hand	0.737	0.263
T18.2 Foreign body in stomach	0.737	0.263
T88 Other complications of surgical and medical care, not elsewhere classified	0.738	0.262
S91 Open wound of ankle and foot	0.739	0.261
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.740	0.260
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.740	0.260
S98 Traumatic amputation of ankle and foot	0.741	0.259
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.743	0.256
T05 Traumatic amputations involving multiple body regions	0.745	0.255
T04 Crushing injuries involving multiple body regions	0.745	0.255
T03 Dislocations, sprains and strains involving multiple body regions	0.745	0.255
T07 Unspecified multiple injuries	0.745	0.255
S62.30 Fracture of other metacarpal bone (closed)	0.746	0.254
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.746	0.253
T87.4 Infection of amputation stump	0.747	0.253
T00.8 Superficial injuries involving other combinations of body regions	0.748	0.252
S20-S29 Injuries to the thorax	0.750	0.250
S60.8 Other superficial injuries of wrist and hand	0.750	0.250
T06 Other injuries involving multiple body regions, not elsewhere classified	0.751	0.249
S64.7 Injury of multiple nerves at wrist and hand level	0.751	0.249
S62.6 Fracture of other finger	0.753	0.247
T80.6 Other serum reactions	0.754	0.246
T80.5 Anaphylactic shock due to serum	0.754	0.246
T80.4 Rh incompatibility reaction	0.754	0.246
T80.3 ABO incompatibility reaction	0.754	0.246
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.754	0.246
T86.4 Liver transplant failure and rejection	0.757	0.243
T86.3 Heart-lung transplant failure and rejection	0.758	0.242
T86.2 Heart transplant failure and rejection	0.758	0.242
T66-T78 Other and unspecified effects of external causes	0.759	0.241
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.759	0.241
S92.3 Fracture of metatarsal bone	0.761	0.239
S65 Injury of blood vessels at wrist and hand level	0.762	0.238
S99 Other and unspecified injuries of ankle and foot	0.762	0.237
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.763	0.237
S95 Injury of blood vessels at ankle and foot level	0.763	0.237
S94 Injury of nerves at ankle and foot level	0.763	0.237
S62.2 Fracture of first metacarpal bone	0.766	0.234
S60.1 Contusion of finger(s) with damage to nail	0.767	0.233
S64.9 Injury of unspecified nerve at wrist and hand level	0.767	0.233
S64.8 Injury of other nerves at wrist and hand level	0.767	0.233
S67 Crushing injury of wrist and hand	0.768	0.232
T17 Foreign body in respiratory tract	0.769	0.231
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.769	0.231
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.769	0.231
T87.2 Complications of other reattached body part	0.771	0.229
T87.1 Complications of reattached (part of) lower extremity	0.771	0.229
T87.0 Complications of reattached (part of) upper extremity	0.771	0.229
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.771	0.229
T00.0 Superficial injuries involving head with neck	0.771	0.229
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.773	0.227
S62.8 Fracture of other and unspecified parts of wrist and hand	0.773	0.227
S27 Injury of other and unspecified intrathoracic organs	0.774	0.226
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.774	0.226
T20-T25 Burns and corrosions of external body surface, specified by site	0.776	0.223
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.776	0.224
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.777	0.223
S91.2 Open wound of toe(s) with damage to nail	0.777	0.223
T86.1 Kidney transplant failure and rejection	0.777	0.222
T87.3 Neuroma of amputation stump	0.779	0.221
T01.8 Open wounds involving other combinations of body regions	0.781	0.219
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.782	0.218
T87.5 Necrosis of amputation stump	0.782	0.218
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.782	0.217
S96.8 Injury of other muscles and tendons at ankle and foot level	0.783	0.217
S68.0 Traumatic amputation of thumb (complete)(partial)	0.783	0.217
S97 Crushing injury of ankle and foot	0.783	0.216
S92.30 Fracture of metatarsal bone (closed)	0.784	0.216
T02.8 Fractures involving other combinations of body regions	0.784	0.215
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.785	0.215
S62.7 Multiple fractures of fingers	0.785	0.215
T02.4 Fractures involving multiple regions of both upper limbs	0.785	0.215
S91.3 Open wound of other parts of foot	0.785	0.215
T59 Toxic effect of other gases, fumes and vapours	0.786	0.214
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.788	0.212
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.788	0.212
T29 Burns and corrosions of multiple body regions	0.788	0.211
T88.9 Complication of surgical and medical care, unspecified	0.789	0.210
T19.0 Foreign body in urethra	0.791	0.209
T15.0 Foreign body in cornea	0.792	0.208
S98.1 Traumatic amputation of one toe	0.792	0.208
T19.2 Foreign body in vulva and vagina	0.792	0.208
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.793	0.207
T85.2 Mechanical complication of intraocular lens	0.795	0.205
T26 Burn and corrosion confined to eye and adnexa	0.795	0.204
T30 Burn and corrosion, body region unspecified	0.796	0.204
S92.2 Fracture of other tarsal bone(s)	0.796	0.204
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.797	0.203
T28 Burn and corrosion of other internal organs	0.798	0.202
T27 Burn and corrosion of respiratory tract	0.798	0.202
S62.1 Fracture of other carpal bone(s)	0.798	0.202
T51 Toxic effect of alcohol	0.798	0.202
T01.3 Open wounds involving multiple regions of lower limb(s)	0.798	0.201
T35 Frostbite involving multiple body regions and unspecified frostbite	0.799	0.201
T34 Frostbite with tissue necrosis	0.799	0.201
T33 Superficial frostbite	0.799	0.201
T63 Toxic effect of contact with venomous animals	0.799	0.201
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.799	0.201
T19.9 Foreign body in genito-urinary tract, part unspecified	0.800	0.200
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.800	0.200
T19.3 Foreign body in uterus [any part]	0.800	0.200
S92.5 Fracture of other toe	0.800	0.200
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.800	0.200
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.800	0.200
S69.7 Multiple injuries of wrist and hand	0.800	0.200
S92.9 Fracture of foot, unspecified	0.800	0.200
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.800	0.200
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.801	0.199
T32 Corrosions classified according to extent of body surface involved	0.801	0.199
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.801	0.199
T01.9 Multiple open wounds, unspecified	0.801	0.198
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.801	0.198
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.801	0.198
T01.0 Open wounds involving head with neck	0.801	0.198
T02.9 Multiple fractures, unspecified	0.801	0.198
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.801	0.198
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.801	0.198
T02.3 Fractures involving multiple regions of one lower limb	0.801	0.198
T02.1 Fractures involving thorax with lower back and pelvis	0.801	0.198
T02.0 Fractures involving head with neck	0.801	0.198
T54 Toxic effect of corrosive substances	0.802	0.198
S62.61 Fracture of other finger (open)	0.803	0.197
T01.2 Open wounds involving multiple regions of upper limb(s)	0.803	0.197
T82.4 Mechanical complication of vascular dialysis catheter	0.804	0.196
S62.4 Multiple fractures of metacarpal bones	0.804	0.196
T88.7 Unspecified adverse effect of drug or medicament	0.804	0.196
T15.8 Foreign body in other and multiple parts of external eye	0.804	0.196
S62.0 Fracture of navicular [scaphoid] bone of hand	0.805	0.195
S50-S59 Injuries to the elbow and forearm	0.805	0.195
T02.5 Fractures involving multiple regions of both lower limbs	0.805	0.195
S62.60 Fracture of other finger (closed)	0.806	0.194
T60 Toxic effect of pesticides	0.806	0.194
T57 Toxic effect of other inorganic substances	0.806	0.194
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.806	0.194
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.806	0.194
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.806	0.194
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.806	0.193
S27.1 Traumatic haemothorax	0.807	0.193
T25 Burn and corrosion of ankle and foot	0.807	0.193
T70 Effects of air pressure and water pressure	0.807	0.193
T83.1 Mechanical complication of other urinary devices and implants	0.807	0.193
S10-S19 Injuries to the neck	0.808	0.192
T68 Hypothermia	0.809	0.191
T31 Burns classified according to extent of body surface involved	0.809	0.191
T88.3 Malignant hyperthermia due to anaesthesis	0.809	0.191
T61 Toxic effect of noxious substances eaten as seafood	0.809	0.190
T52 Toxic effect of organic solvents	0.809	0.190
S27.2 Traumatic heamopneumothorax	0.809	0.190
S92.7 Multiple fractures of foot	0.810	0.190
T56 Toxic effect of metals	0.810	0.190
S92.4 Fracture of great toe	0.810	0.190
T15.1 Foreign body in conjunctival sac	0.810	0.190
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.810	0.190
S68.8 Traumatic amputation of other parts of wrist and hand	0.810	0.190
S68.4 Traumatic amputation of hand at wrist level	0.810	0.190
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.810	0.190
T02.2 Fractures involving multiple regions of one upper limb	0.810	0.189
T55 Toxic effect of soaps and detergents	0.811	0.189
S90 Superficial injury of ankle and foot	0.811	0.189
T62 Toxic effect of other noxious substances eaten as food	0.811	0.188
T88.1 Other complications following immunisation, not elsewhere classified	0.812	0.188
T88.0 Infection following immunisation	0.812	0.188
S92.1 Fracture of talus	0.812	0.188
S91.7 Multiple open wounds of ankle and foot	0.813	0.187
S69.8 Other specified injuries of wrist and hand	0.813	0.187
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.813	0.186
S62.20 Fracture of first metacarpal bone (closed)	0.814	0.186
T66 Unspecified effects of radiation	0.814	0.186
S98.4 Traumatic amputation of foot, level unspecified	0.814	0.186
S98.3 Traumatic amputation of other parts of foot	0.814	0.186
S98.2 Traumatic amputation of two or more toes	0.814	0.186
S98.0 Traumatic amputation of foot at ankle level	0.814	0.186
T19.1 Foreign body in bladder	0.816	0.183
T03.9 Multiple dislocations, sprains and strains, unspecified	0.817	0.183
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.817	0.183
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.817	0.183
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.817	0.183
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.817	0.183
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.817	0.183
T03.0 Dislocations, sprains and strains involving head with neck	0.817	0.183
T04.9 Multiple crushing injuries, unspecified	0.817	0.183
T04.8 Crushing injuries involving other combinations of body regions	0.817	0.183
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.817	0.183
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.817	0.183
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.817	0.183
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.817	0.183
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.817	0.183
T04.0 Crushing injuries involving head with neck	0.817	0.183
T05.9 Multiple traumatic amputations, unspecified	0.817	0.183
T05.8 Traumatic amputations involving other combinations of body regions	0.817	0.183
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.817	0.183
T05.5 Traumatic amputation of both legs [any level]	0.817	0.183
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.817	0.183
T05.3 Traumatic amputation of both feet	0.817	0.183
T05.2 Traumatic amputation of both arms [any level]	0.817	0.183
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.817	0.183
T05.0 Traumatic amputation of both hands	0.817	0.183
T58 Toxic effect of carbon monoxide	0.817	0.182
S69.9 Unspecified injury of wrist and hand	0.818	0.182
T15.9 Foreign body on external eye, unspecified	0.818	0.182
S26 Injury of heart	0.819	0.181
T88.5 Other complications of anaesthesia	0.819	0.181
T17.2 Foreign body in pharynx	0.819	0.181
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.819	0.181
S27.3 Other injuries of lung	0.820	0.180
T59.9 Gases, fumes and vapours, unspecified	0.820	0.180
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.820	0.179
S25 Injury of blood vessels of thorax	0.820	0.179
T06.8 Other specified injuries involving multiple body regions	0.821	0.179
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.821	0.179
T06.3 Injuries of blood vessels involving multiple body regions	0.821	0.179
T06.2 Injuries of nerves involving multiple body regions	0.821	0.179
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.821	0.179
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.821	0.179
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.823	0.177
S64.4 Injury of digital nerve of other finger	0.823	0.177
T82.0 Mechanical complication of heart valve prosthesis	0.823	0.176
S65.0 Injury of ulnar artery at wrist and hand level	0.824	0.175
T80.2 Infections following infusion, transfusion and therapeutic injection	0.825	0.175
S65.4 Injury of blood vessel(s) of thumb	0.825	0.175
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.825	0.174
S91.1 Open wound of toe(s) without damage to nail	0.826	0.174
T17.3 Foreign body in larynx	0.826	0.174
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.827	0.173
T74 Maltreatment syndromes	0.827	0.173
T73 Effects of other deprivation	0.827	0.173
T69 Other effects of reduced temperature	0.827	0.173
T67 Effects of heat and light	0.827	0.173
T06.4 Injuries of muscles and tendons involving multiple body regions	0.827	0.172
T79 Certain early complications of trauma, not elsewhere classified	0.828	0.172
S99.9 Unspecified injury of ankle and foot	0.828	0.172
S92.31 Fracture of metatarsal bone (open)	0.828	0.172
T02.80 Fractures involving other combinations of body regions (closed)	0.828	0.171
T65 Toxic effect of other and unspecified substances	0.829	0.171
S20 Superficial injury of thorax	0.829	0.171
T51.0 Ethanol	0.829	0.171
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.829	0.170
S65.8 Injury of other blood vessels at wrist and hand level	0.829	0.170
S65.7 Injury of multiple blood vessels at wrist and hand level	0.829	0.170
S65.3 Injury of deep palmar arch	0.829	0.170
S65.2 Injury of superficial palmar arch	0.829	0.170
S99.7 Multiple injuries of ankle and foot	0.829	0.170
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.830	0.170
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.830	0.170
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.830	0.170
S94.9 Injury of unspecified nerve at ankle and foot level	0.830	0.170
S94.8 Injury of other nerves at ankle and foot level	0.830	0.170
S94.7 Injury of multiple nerves at ankle and foot level	0.830	0.170
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.830	0.170
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.830	0.170
S94.1 Injury of medial plantar nerve	0.830	0.170
S94.0 Injury of lateral plantar nerve	0.830	0.170
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.830	0.170
S95.8 Injury of other blood vessels at ankle and foot level	0.830	0.170
S95.7 Injury of multiple blood vessels at ankle and foot level	0.830	0.170
S95.2 Injury of dorsal vein of foot	0.830	0.170
S95.1 Injury of plantar artery of foot	0.830	0.170
S95.0 Injury of dorsal artery of foot	0.830	0.170
S99.8 Other specified injuries of ankle and foot	0.831	0.169
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.832	0.168
S62.31 Fracture of other metacarpal bone (open)	0.832	0.168
S92.0 Fracture of calcaneus	0.832	0.168
S62.21 Fracture of first metacarpal bone (open)	0.832	0.168
S24 Injury of nerves and spinal cord at thorax level	0.833	0.167
T17.4 Foreign body in trachea	0.834	0.166
T17.1 Foreign body in nostril	0.834	0.166
T17.0 Foreign body in nasal sinus	0.834	0.166
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.835	0.165
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.835	0.165
S65.5 Injury of blood vessel(s) of other finger	0.836	0.164
T25.2 Burn of second degree of ankle and foot	0.836	0.164
S27.8 Injury of other specified intrathoracic organs	0.837	0.163
S27.9 Injury of unspecified intrathoracic organ	0.838	0.162
S27.7 Multiple injuries of intrathoracic organs	0.838	0.162
S27.6 Injury of pleura	0.838	0.162
S27.5 Injury of thoracic trachea	0.838	0.162
S27.4 Injury of bronchus	0.838	0.162
S93.0 Dislocation of ankle joint	0.839	0.161
T75 Effects of other external causes	0.839	0.161
S80-S89 Injuries to the knee and lower leg	0.839	0.161
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.840	0.160
T71 Asphyxiation	0.840	0.160
S29 Other and unspecified injuries of thorax	0.841	0.159

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations