TreeWAS – Variant ID: rs4712980

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
K90 Intestinal malabsorption	0.929	0.071	0.000
K90.9 Intestinal malabsorption, unspecified	0.894	0.106	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.831	0.169	0.000
K90.3 Pancreatic steatorrhoea	0.666	0.334	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.666	0.334	0.000
K90.1 Tropical sprue	0.666	0.334	0.000
K90.8 Other intestinal malabsorption	0.613	0.387	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.308	0.692	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.296	0.704	0.000
C85.1 B-cell lymphoma, unspecified	0.284	0.716	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.235	0.765	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.230	0.770	0.000
C85.0 Lymphosarcoma	0.212	0.788	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.187	0.813	0.000
C81 Hodgkin's disease	0.173	0.827	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.172	0.828	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.168	0.832	0.000
C83.0 Small cell (diffuse)	0.166	0.834	0.000
C83.3 Large cell (diffuse)	0.158	0.841	0.000
C95 Leukaemia of unspecified cell type	0.151	0.848	0.000
C81.1 Nodular sclerosis	0.149	0.851	0.000
C84.5 Other and unspecified T-cell lymphomas	0.148	0.852	0.000
C81.2 Mixed cellularity	0.148	0.852	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.134	0.866	0.000
C94 Other leukaemias of specified cell type	0.134	0.866	0.000
C81.0 Lymphocytic predominance	0.133	0.867	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.129	0.871	0.000
C84.4 Peripheral T-cell lymphoma	0.129	0.871	0.000
C86 Other specified types of T/NK-cell lymphoma	0.129	0.871	0.000
C93 Monocytic leukaemia	0.129	0.871	0.000
C81.9 Hodgkin's disease, unspecified	0.127	0.873	0.000
C81.7 Other Hodgkin's disease	0.124	0.875	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.124	0.875	0.000
C81.3 Lymphocytic depletion	0.124	0.875	0.000
C83.6 Undifferentiated (diffuse)	0.124	0.876	0.000
C83.5 Lymphoblastic (diffuse)	0.124	0.876	0.000
C83.4 Immunoblastic (diffuse)	0.124	0.876	0.000
C83.2 Mixed small and large cell (diffuse)	0.124	0.876	0.000
E03.9 Hypothyroidism, unspecified	0.124	0.876	0.000
C88 Malignant immunoproliferative diseases	0.123	0.877	0.000
C84.0 Mycosis fungoides	0.122	0.878	0.000
C95.9 Leukaemia, unspecified	0.121	0.879	0.000
C83.7 Burkitt's tumour	0.121	0.879	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.121	0.879	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.121	0.879	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.121	0.879	0.000
C84.3 Lymphoepithelioid lymphoma	0.121	0.879	0.000
C84.2 T-zone lymphoma	0.121	0.879	0.000
C84.1 Sezary's diease	0.121	0.879	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.119	0.881	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.114	0.886	0.000
C95.0 Acute leukaemia of unspecified cell type	0.111	0.889	0.000
C95.7 Other leukaemia of unspecified cell type	0.109	0.891	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.109	0.891	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.104	0.896	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.100	0.900	0.000
C83.1 Small cleaved cell (diffuse)	0.098	0.901	0.000
C94.7 Other specified leukaemias	0.096	0.904	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.096	0.904	0.000
C94.5 Acute myelofibrosis	0.096	0.904	0.000
C94.4 Acute panmyelosis	0.096	0.904	0.000
C94.3 Mast cell leukaemia	0.096	0.904	0.000
C94.2 Acute megakaryoblastic leukaemia	0.096	0.904	0.000
C94.1 Chronic erythraemia	0.096	0.904	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.096	0.904	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.096	0.904	0.000
C96.8 Histiocytic sarcoma	0.096	0.904	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.096	0.904	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.096	0.904	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.096	0.904	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.096	0.904	0.000
C96.3 True histiocytic lymphoma	0.096	0.904	0.000
C96.2 Malignant mast cell tumour	0.096	0.904	0.000
C96.1 Malignant histiocytosis	0.096	0.904	0.000
C96.0 Letterer-Siwe disease	0.096	0.904	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.092	0.907	0.000
C86.4 Blastic NK-cell lymphoma	0.092	0.907	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.092	0.907	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.092	0.907	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.092	0.907	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.092	0.907	0.000
C93.9 Monocytic leukaemia, unspecified	0.092	0.907	0.000
C93.7 Other monocytic leukaemia	0.092	0.907	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.092	0.907	0.000
C93.2 Subacute monocytic leukaemia	0.092	0.907	0.000
C93.0 Acute monocytic leukaemia	0.092	0.907	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.088	0.911	0.000
C88.7 Other malignant immunoproliferative diseases	0.088	0.911	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.088	0.911	0.000
C88.3 Immunoproliferative small intestinal disease	0.088	0.911	0.000
C88.2 Gamma heavy chain disease	0.088	0.911	0.000
C88.1 Alpha heavy chain disease	0.088	0.911	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.087	0.913	0.000
C93.1 Chronic monocytic leukaemia	0.087	0.913	0.000
C90.1 Plasma cell leukaemia	0.083	0.917	0.000
C82.3 Follicular lymphoma grade IIIa	0.080	0.920	0.000
C90.2 Plasmacytoma, extramedullary	0.078	0.922	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.078	0.922	0.000
C82.4 Follicular lymphoma grade IIIb	0.077	0.923	0.000
C82.0 Small cleaved cell, follicular	0.073	0.927	0.000
C82.6 Cutaneous follicle centre lymphoma	0.072	0.928	0.000
C82.5 Diffuse follicle centre lymphoma	0.072	0.928	0.000
C82.2 Large cell, follicular	0.068	0.932	0.000
E83 Disorders of mineral metabolism	0.006	0.932	0.062
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.061	0.939	0.000
C90.3 Solitary plasmacytoma	0.061	0.939	0.000
K90-K93 Other diseases of the digestive system	0.059	0.940	0.001
C91 Lymphoid leukaemia	0.059	0.941	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.056	0.943	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.056	0.944	0.000
C92 Myeloid leukaemia	0.052	0.948	0.000
E03 Other hypothyroidism	0.051	0.949	0.000
K81.0 Acute cholecystitis	0.000	0.949	0.051
E83.9 Disorder of mineral metabolism, unspecified	0.004	0.951	0.044
E83.8 Other disorders of mineral metabolism	0.004	0.951	0.044
E83.2 Disorders of zinc metabolism	0.004	0.951	0.044
E83.0 Disorders of copper metabolism	0.004	0.951	0.044
E83.3 Disorders of phosphorus metabolism	0.002	0.953	0.045
C91.9 Lymphoid leukaemia, unspecified	0.045	0.955	0.000
C91.5 Adult T-cell leukaemia	0.043	0.957	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.042	0.957	0.001
C91.8 Mature B-cell leukaemia Burkitt-type	0.042	0.957	0.000
C91.7 Other lymphoid leukaemia	0.042	0.957	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.042	0.957	0.000
C91.3 Prolymphocytic leukaemia	0.042	0.957	0.000
C91.2 Subacute lymphocytic leukaemia	0.042	0.957	0.000
C92.9 Myeloid leukaemia, unspecified	0.039	0.961	0.000
C90.0 Multiple myeloma	0.039	0.961	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.036	0.962	0.002
C91.0 Acute lymphoblastic leukaemia	0.037	0.962	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.037	0.962	0.000
C92.7 Other myeloid leukaemia	0.037	0.962	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.037	0.962	0.000
C92.5 Acute myelomonocytic leukaemia	0.037	0.962	0.000
C92.3 Myeloid sarcoma	0.037	0.962	0.000
C92.2 Subacute myeloid leukaemia	0.037	0.962	0.000
E03.5 Myxoedema coma	0.037	0.963	0.000
E03.4 Atrophy of thyroid (acquired)	0.037	0.963	0.000
E03.3 Postinfectious hypothyroidism	0.037	0.963	0.000
E03.1 Congenital hypothyroidism without goitre	0.037	0.963	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.037	0.963	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.036	0.964	0.000
K81 Cholecystitis	0.000	0.965	0.035
C92.4 Acute promyelocytic leukaemia	0.031	0.968	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.031	0.969	0.001
K93.1 Megacolon in Chagas' disease	0.031	0.969	0.001
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.031	0.969	0.001
K81.9 Cholecystitis, unspecified	0.000	0.969	0.031
M20.1 Hallux valgus (acquired)	0.000	0.969	0.031
K81.8 Other cholecystitis	0.000	0.972	0.028
R31 Unspecified haematuria	0.000	0.972	0.028
E00-E07 Disorders of thyroid gland	0.025	0.975	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.976	0.024
C91.4 Hairy-cell leukaemia	0.023	0.976	0.001
C92.1 Chronic myeloid leukaemia	0.023	0.977	0.000
E05.9 Thyrotoxicosis, unspecified	0.023	0.977	0.000
N87.0 Mild cervical dysplasia	0.000	0.977	0.023
E03.8 Other specified hypothyroidism	0.023	0.977	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.023	0.977	0.000
K81.1 Chronic cholecystitis	0.000	0.977	0.023
E02 Subclinical iodine-deficiency hypothyroidism	0.021	0.979	0.000
C91.1 Chronic lymphocytic leukaemia	0.019	0.981	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.018	0.982	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.018	0.982	0.000
E00 Congenital iodine-deficiency syndrome	0.018	0.982	0.000
E05.8 Other thyrotoxicosis	0.017	0.983	0.000
E05.5 Thyroid crisis or storm	0.017	0.983	0.000
E05.4 Thyrotoxicosis factitia	0.017	0.983	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.017	0.983	0.000
E07 Other disorders of thyroid	0.016	0.984	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.015	0.984	0.000
E16.2 Hypoglycaemia, unspecified	0.014	0.986	0.000
S81.8 Open wound of other parts of lower leg	0.014	0.986	0.000
E16 Other disorders of pancreatic internal secretion	0.014	0.986	0.000
E27.1 Primary adrenocortical insufficiency	0.014	0.986	0.000
S80 Superficial injury of lower leg	0.014	0.986	0.000
S80.8 Other superficial injuries of lower leg	0.014	0.986	0.000
S80.0 Contusion of knee	0.013	0.986	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.013	0.987	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.013	0.987	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.013	0.987	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.013	0.987	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.013	0.987	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.013	0.987	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.013	0.987	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.013	0.987	0.000
E07.8 Other specified disorders of thyroid	0.013	0.987	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.013	0.987	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.987	0.013
E16.0 Drug-induced hypoglycaemia without coma	0.013	0.987	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.013	0.987	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.987	0.013
S80.1 Contusion of other and unspecified parts of lower leg	0.012	0.988	0.000
K40 Inguinal hernia	0.000	0.988	0.012
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.988	0.012
E83.4 Disorders of magnesium metabolism	0.007	0.988	0.005
E27 Other disorders of adrenal gland	0.012	0.988	0.000
M20 Acquired deformities of fingers and toes	0.000	0.988	0.012
E07.1 Dyshormogenetic goitre	0.012	0.988	0.000
E07.0 Hypersecretion of calcitonin	0.012	0.988	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.988	0.012
C92.0 Acute myeloid leukaemia	0.011	0.988	0.000
E53.8 Deficiency of other specified B group vitamins	0.012	0.988	0.000
E50-E64 Other nutritional deficiencies	0.012	0.988	0.000
S81 Open wound of lower leg	0.011	0.989	0.000
E53 Deficiency of other B group vitamins	0.011	0.989	0.000
S80-S89 Injuries to the knee and lower leg	0.011	0.989	0.000
E20-E35 Disorders of other endocrine glands	0.011	0.989	0.000
N05.9 Unspecified	0.011	0.989	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.011	0.989	0.000
N40 Hyperplasia of prostate	0.000	0.989	0.011
C50.2 Upper-inner quadrant of breast	0.000	0.989	0.011
E06 Thyroiditis	0.010	0.990	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.990	0.010
K44 Diaphragmatic hernia	0.000	0.990	0.010
E16.9 Disorder of pancreatic internal secretion, unspecified	0.010	0.990	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.010	0.990	0.000
E16.4 Abnormal secretion of gastrin	0.010	0.990	0.000
E16.3 Increased secretion of glucagon	0.010	0.990	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.010	0.990	0.000
E27.2 Addisonian crisis	0.010	0.990	0.000
S83.2 Tear of meniscus, current	0.010	0.990	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.990	0.010
E61 Deficiency of other nutrient elements	0.010	0.990	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.009	0.990	0.000
E40-E46 Malnutrition	0.010	0.990	0.000
E15 Nondiabetic hypoglycaemic coma	0.009	0.990	0.000
K40-K46 Hernia	0.000	0.990	0.010
S80.7 Multiple superficial injuries of lower leg	0.009	0.990	0.000
S84 Injury of nerves at lower leg level	0.009	0.990	0.000
S83.7 Injury to multiple structures of knee	0.009	0.991	0.000
N05 Unspecified nephritic syndrome	0.009	0.991	0.000
S83.3 Tear of articular cartilage of knee, current	0.009	0.991	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.991	0.009
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.991	0.009
E56 Other vitamin deficiencies	0.009	0.991	0.000
E16.1 Other hypoglycaemia	0.009	0.991	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.991	0.009
E27.5 Adrenomedullary hyperfunction	0.009	0.991	0.000
E27.0 Other adrenocortical overactivity	0.009	0.991	0.000
S83.1 Dislocation of knee	0.009	0.991	0.000
N97.9 Female infertility, unspecified	0.000	0.991	0.009
E64 Sequelae of malnutrition and other nutritional deficiencies	0.008	0.991	0.000
E63 Other nutritional deficiencies	0.008	0.991	0.000
E50 Vitamin A deficiency	0.008	0.991	0.000
E60 Dietary zinc deficiency	0.008	0.991	0.000
E59 Dietary selenium deficiency	0.008	0.991	0.000
E54 Ascorbic acid deficiency	0.008	0.991	0.000
E52 Niacin deficiency [pellagra]	0.008	0.991	0.000
E22 Hyperfunction of pituitary gland	0.008	0.991	0.000
E31 Polyglandular dysfunction	0.008	0.992	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.008	0.992	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.992	0.008
E53.1 Pyridoxine deficiency	0.008	0.992	0.000
E53.0 Riboflavin deficiency	0.008	0.992	0.000
S89 Other and unspecified injuries of lower leg	0.008	0.992	0.000
S88 Traumatic amputation of lower leg	0.008	0.992	0.000
S87 Crushing injury of lower leg	0.008	0.992	0.000
S85 Injury of blood vessels at lower leg level	0.008	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.008	0.992	0.000
S81.9 Open wound of lower leg, part unspecified	0.008	0.992	0.000
E51 Thiamine deficiency	0.008	0.992	0.000
N05.2 Diffuse membranous glomerulonephritis	0.008	0.992	0.000
N05.1 Focal and segmental glomerular lesions	0.008	0.992	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.008	0.992	0.000
E32 Diseases of thymus	0.008	0.992	0.000
E30 Disorders of puberty, not elsewhere classified	0.008	0.992	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.992	0.008
E61.1 Iron deficiency	0.008	0.992	0.000
E83.5 Disorders of calcium metabolism	0.007	0.992	0.001
S83.0 Dislocation of patella	0.008	0.992	0.000
E25 Adrenogenital disorders	0.008	0.992	0.000
K45 Other abdominal hernia	0.000	0.992	0.008
E20 Hypoparathyroidism	0.008	0.992	0.000
S89.8 Other specified injuries of lower leg	0.008	0.992	0.000
E34 Other endocrine disorders	0.008	0.992	0.000
E06.4 Drug-induced thyroiditis	0.008	0.992	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.008	0.992	0.000
E06.1 Subacute thyroiditis	0.008	0.992	0.000
E06.0 Acute thyroiditis	0.008	0.992	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.008	0.992	0.000
E26 Hyperaldosteronism	0.008	0.992	0.000
K42 Umbilical hernia	0.000	0.992	0.008
E61.2 Magnesium deficiency	0.008	0.992	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.008	0.992	0.000
E06.5 Other chronic thyroiditis	0.007	0.992	0.000
E23.2 Diabetes insipidus	0.008	0.992	0.000
E58 Dietary calcium deficiency	0.008	0.992	0.000
E22.1 Hyperprolactinaemia	0.008	0.992	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.992	0.000
E46 Unspecified protein-energy malnutrition	0.007	0.992	0.000
E53.9 Vitamin B deficiency, unspecified	0.007	0.993	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.993	0.007
N05.8 Other	0.007	0.993	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.993	0.007
E24 Cushing's syndrome	0.007	0.993	0.000
E61.9 Deficiency of nutrient element, unspecified	0.007	0.993	0.000
E61.8 Deficiency of other specified nutrient elements	0.007	0.993	0.000
E61.7 Deficiency of multiple nutrient elements	0.007	0.993	0.000
E61.6 Vanadium deficiency	0.007	0.993	0.000
E61.5 Molybdenum deficiency	0.007	0.993	0.000
E61.4 Chromium deficiency	0.007	0.993	0.000
E61.3 Manganese deficiency	0.007	0.993	0.000
E61.0 Copper deficiency	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
E56.1 Deficiency of vitamin K	0.007	0.993	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.007	0.993	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.993	0.007
S84.9 Injury of unspecified nerve at lower leg level	0.007	0.993	0.000
S84.8 Injury of other nerves at lower leg level	0.007	0.993	0.000
S84.7 Injury of multiple nerves at lower leg level	0.007	0.993	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.007	0.993	0.000
S84.0 Injury of tibial nerve at lower leg level	0.007	0.993	0.000
S86 Injury of muscle and tendon at lower leg level	0.007	0.993	0.000
E07.9 Disorder of thyroid, unspecified	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
N05.6 Dense deposit disease	0.007	0.993	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.993	0.000
N05.0 Minor glomerular abnormality	0.007	0.993	0.000
K41 Femoral hernia	0.000	0.993	0.007
E28 Ovarian dysfunction	0.007	0.993	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.007	0.993	0.000
N87 Dysplasia of cervix uteri	0.000	0.993	0.007
S81.0 Open wound of knee	0.007	0.993	0.000
E31.0 Autoimmune polyglandular failure	0.007	0.993	0.000
E56.9 Vitamin deficiency, unspecified	0.007	0.993	0.000
E56.8 Deficiency of other vitamins	0.007	0.993	0.000
E56.0 Deficiency of vitamin E	0.007	0.993	0.000
E55 Vitamin D deficiency	0.007	0.993	0.000
M20.0 Deformity of finger(s)	0.000	0.993	0.007
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.007	0.993	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.007	0.993	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.007	0.993	0.000
H26.9 Cataract, unspecified	0.006	0.994	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.994	0.006
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.006	0.994	0.000
E50.8 Other manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.006	0.994	0.000
E50.5 Vitamin A deficiency with night blindness	0.006	0.994	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.006	0.994	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.006	0.994	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.006	0.994	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.006	0.994	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.006	0.994	0.000
E63.9 Nutritional deficiency, unspecified	0.006	0.994	0.000
E63.8 Other specified nutritional deficiencies	0.006	0.994	0.000
E63.1 Imbalance of constituents of food intake	0.006	0.994	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.006	0.994	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.006	0.994	0.000
E64.8 Sequelae of other nutritional deficiencies	0.006	0.994	0.000
E64.3 Sequelae of rickets	0.006	0.994	0.000
E64.2 Sequelae of vitamin C deficiency	0.006	0.994	0.000
E64.1 Sequelae of vitamin A deficiency	0.006	0.994	0.000
E64.0 Sequelae of protein-energy malnutrition	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.994	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.994	0.000
E31.8 Other polyglandular dysfunction	0.006	0.994	0.000
E31.1 Polyglandular hyperfunction	0.006	0.994	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.006	0.994	0.000
E23.7 Disorder of pituitary gland, unspecified	0.006	0.994	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
S52.6 Fracture of lower end of both ulna and radius	0.006	0.994	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.006	0.994	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.994	0.006
S89.7 Multiple injuries of lower leg	0.006	0.994	0.000
S89.1 Other specified injuries of lower leg	0.006	0.994	0.000
S89.0 Multiple injuries of lower leg	0.006	0.994	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.006	0.994	0.000
S85.8 Injury of other blood vessels at lower leg level	0.006	0.994	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.006	0.994	0.000
S85.5 Injury of popliteal vein	0.006	0.994	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.006	0.994	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.006	0.994	0.000
S85.2 Injury of peroneal artery	0.006	0.994	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.006	0.994	0.000
S85.0 Injury of popliteal artery	0.006	0.994	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.006	0.994	0.000
S87.0 Crushing injury of knee	0.006	0.994	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.006	0.994	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.006	0.994	0.000
S88.0 Traumatic amputation at knee level	0.006	0.994	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
S81.7 Multiple open wounds of lower leg	0.006	0.994	0.000
E51.9 Thiamine deficiency, unspecified	0.006	0.994	0.000
E51.8 Other manifestations of thiamine deficiency	0.006	0.994	0.000
E51.1 Beriberi	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.006	0.994	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.994	0.000
E30.8 Other disorders of puberty	0.006	0.994	0.000
E30.1 Precocious puberty	0.006	0.994	0.000
E30.0 Delayed puberty	0.006	0.994	0.000
E32.9 Disease of thymus, unspecified	0.006	0.994	0.000
E32.8 Other diseases of thymus	0.006	0.994	0.000
E32.1 Abscess of thymus	0.006	0.994	0.000
E32.0 Persistent hyperplasia of thymus	0.006	0.994	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.994	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E29 Testicular dysfunction	0.006	0.994	0.000
E25.9 Adrenogenital disorder, unspecified	0.006	0.994	0.000
E25.8 Other adrenogenital disorders	0.006	0.994	0.000
K45.1 Other specified abdominal hernia with gangrene	0.000	0.994	0.006
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.994	0.006
E34.5 Androgen resistance syndrome	0.006	0.994	0.000
E34.4 Constitutional tall stature	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.994	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.006	0.994	0.000
E26.8 Other hyperaldosteronism	0.006	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.006	0.994	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.994	0.006
E51.2 Wernicke's encephalopathy	0.006	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.994	0.000
N18.3 Chronic kidney disease, stage 3	0.006	0.994	0.000
K46 Unspecified abdominal hernia	0.000	0.994	0.006
E06.9 Thyroiditis, unspecified	0.005	0.994	0.000
E34.8 Other specified endocrine disorders	0.005	0.994	0.000
E34.0 Carcinoid syndrome	0.005	0.994	0.000
E26.0 Primary hyperaldosteronism	0.005	0.994	0.000
E24.8 Other Cushing's syndrome	0.005	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.005	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.005	0.994	0.000
E24.1 Nelson's syndrome	0.005	0.994	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.006	0.994	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.995	0.005
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.005	0.995	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.995	0.005
E28.3 Primary ovarian failure	0.005	0.995	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.005	0.995	0.000
S86.0 Injury of Achilles tendon	0.005	0.995	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.005	0.995	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.005	0.995	0.000
F05.9 Delirium, unspecified	0.005	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.995	0.005
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.995	0.005
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.995	0.005
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.995	0.005
K92 Other diseases of digestive system	0.003	0.995	0.002
E28.9 Ovarian dysfunction, unspecified	0.005	0.995	0.000
E28.8 Other ovarian dysfunction	0.005	0.995	0.000
E28.1 Androgen excess	0.005	0.995	0.000
E28.0 Oestrogen excess	0.005	0.995	0.000
K43 Ventral hernia	0.000	0.995	0.005
E55.0 Rickets, active	0.005	0.995	0.000
S80.9 Superficial injury of lower leg, unspecified	0.005	0.995	0.000
Y44.2 Anticoagulants	0.000	0.995	0.005
S52.00 Fracture of upper end of ulna (closed)	0.005	0.995	0.000
S51.9 Open wound of forearm, part unspecified	0.005	0.995	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.005	0.995	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.995	0.005
K91.1 Postgastric surgery syndromes	0.005	0.995	0.000
K91.5 Postcholecystectomy syndrome	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.004	0.995	0.000
E70-E90 Metabolic disorders	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.995	0.000
E29.8 Other testicular dysfunction	0.004	0.995	0.000
E29.0 Testicular hyperfunction	0.004	0.995	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.995	0.000
E73 Lactose intolerance	0.004	0.996	0.000
S52 Fracture of forearm	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.004	0.996	0.000
S52.0 Fracture of upper end of ulna	0.004	0.996	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.996	0.004
K92.1 Melaena	0.000	0.996	0.004
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.996	0.000
M10.94 Gout, unspecified (Hand)	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
S51.0 Open wound of elbow	0.004	0.996	0.000
M10.9 Gout, unspecified	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
S51 Open wound of forearm	0.004	0.996	0.000
N87.1 Moderate cervical dysplasia	0.000	0.996	0.004
E84 Cystic fibrosis	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations