TreeWAS – Variant ID: rs4720952

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.082	0.918	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.076	0.924	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.074	0.926	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.064	0.936	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.063	0.937	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.062	0.938	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.060	0.940	0.000
O75.0 Maternal distress during labour and delivery	0.059	0.941	0.000
E05.5 Thyroid crisis or storm	0.055	0.945	0.000
E05.4 Thyrotoxicosis factitia	0.055	0.945	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.055	0.945	0.000
O75.8 Other specified complications of labour and delivery	0.055	0.945	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.055	0.945	0.000
O75.3 Other infection during labour	0.048	0.952	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.048	0.952	0.000
O75.9 Complication of labour and delivery, unspecified	0.045	0.955	0.000
O75.4 Other complications of obstetric surgery and procedures	0.045	0.955	0.000
O75.1 Shock during or following labour and delivery	0.045	0.955	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.043	0.956	0.000
E05.8 Other thyrotoxicosis	0.041	0.958	0.000
F17.2 Dependence syndrome	0.031	0.969	0.000
E00-E07 Disorders of thyroid gland	0.026	0.974	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.023	0.977	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.019	0.981	0.000
E00 Congenital iodine-deficiency syndrome	0.019	0.981	0.000
E07 Other disorders of thyroid	0.018	0.982	0.000
E04 Other non-toxic goitre	0.018	0.982	0.000
E04.1 Non-toxic single thyroid nodule	0.016	0.984	0.000
E07.8 Other specified disorders of thyroid	0.015	0.985	0.000
E06 Thyroiditis	0.015	0.985	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.986	0.014
E03 Other hypothyroidism	0.014	0.986	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.014	0.986	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.014	0.986	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.014	0.986	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.014	0.986	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.014	0.986	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.014	0.986	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.014	0.986	0.000
E07.1 Dyshormogenetic goitre	0.013	0.987	0.000
E07.0 Hypersecretion of calcitonin	0.013	0.987	0.000
E04.8 Other specified non-toxic goitre	0.013	0.987	0.000
E04.9 Non-toxic goitre, unspecified	0.011	0.989	0.000
E06.1 Subacute thyroiditis	0.011	0.989	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.011	0.989	0.000
I44.1 Atrioventricular block, second degree	0.000	0.989	0.011
E06.9 Thyroiditis, unspecified	0.011	0.989	0.000
E03.1 Congenital hypothyroidism without goitre	0.011	0.989	0.000
E06.4 Drug-induced thyroiditis	0.011	0.989	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.011	0.989	0.000
E06.0 Acute thyroiditis	0.011	0.989	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.010	0.989	0.000
E06.5 Other chronic thyroiditis	0.010	0.990	0.000
E03.5 Myxoedema coma	0.010	0.990	0.000
E03.4 Atrophy of thyroid (acquired)	0.010	0.990	0.000
E03.3 Postinfectious hypothyroidism	0.010	0.990	0.000
E04.0 Non-toxic diffuse goitre	0.010	0.990	0.000
E04.2 Non-toxic multinodular goitre	0.010	0.990	0.000
E03.8 Other specified hypothyroidism	0.010	0.990	0.000
E07.9 Disorder of thyroid, unspecified	0.009	0.991	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.009	0.991	0.000
D12.2 Ascending colon	0.000	0.992	0.008
M84 Disorders of continuity of bone	0.008	0.992	0.000
E21.3 Hyperparathyroidism, unspecified	0.008	0.992	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.008	0.992	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.008	0.992	0.000
M84.4 Pathological fracture, not elsewhere classified	0.008	0.992	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.007	0.993	0.000
M84.8 Other disorders of continuity of bone	0.007	0.993	0.000
M84.0 Malunion of fracture	0.007	0.993	0.000
M84.2 Delayed union of fracture	0.007	0.993	0.000
M84.01 Malunion of fracture (Shoulder region)	0.007	0.993	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.007	0.993	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.007	0.993	0.000
D44.8 Pluriglandular involvement	0.007	0.993	0.000
D44.3 Pituitary gland	0.007	0.993	0.000
I44.6 Other and unspecified fascicular block	0.000	0.994	0.006
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
D44.0 Thyroid gland	0.006	0.994	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.006	0.994	0.000
M84.03 Malunion of fracture (Forearm)	0.006	0.994	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.006	0.994	0.000
D44.1 Adrenal gland	0.006	0.994	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.994	0.006
M84.9 Disorder of continuity of bone, unspecified	0.006	0.994	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.006	0.994	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.006	0.994	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.006	0.994	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.006	0.994	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.006	0.994	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.006	0.994	0.000
M84.22 Delayed union of fracture (Upper arm)	0.005	0.994	0.000
D44.6 Carotid body	0.006	0.994	0.000
D44.7 Aortic body and other paraganglia	0.006	0.994	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.005	0.994	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.005	0.994	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.994	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.005	0.994	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.005	0.994	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.005	0.994	0.000
M84.06 Malunion of fracture (Lower leg)	0.005	0.994	0.000
M84.26 Delayed union of fracture (Lower leg)	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.005	0.995	0.000
M84.02 Malunion of fracture (Upper arm)	0.005	0.995	0.000
M84.09 Malunion of fracture (Site unspecified)	0.005	0.995	0.000
M84.00 Malunion of fracture (Multiple sites)	0.005	0.995	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.005	0.995	0.000
M84.88 Other disorders of continuity of bone (Other)	0.005	0.995	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.005	0.995	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.005	0.995	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.005	0.995	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.005	0.995	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.005	0.995	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.005	0.995	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.005	0.995	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.005	0.995	0.000
M84.28 Delayed union of fracture (Other)	0.005	0.995	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.005	0.995	0.000
M84.24 Delayed union of fracture (Hand)	0.005	0.995	0.000
M84.23 Delayed union of fracture (Forearm)	0.005	0.995	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.005	0.995	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.005	0.995	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
D44.5 Pineal gland	0.005	0.995	0.000
D44.2 Parathyroid gland	0.005	0.995	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.995	0.005
M84.08 Malunion of fracture (Other)	0.005	0.995	0.000
D44.9 Endocrine gland, unspecified	0.005	0.995	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.995	0.005
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.005	0.995	0.000
F17.3 Withdrawal state	0.005	0.995	0.000
I44.4 Left anterior fascicular block	0.000	0.995	0.005
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.005	0.995	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.995	0.005
F17.8 Other mental and behavioural disorders	0.005	0.995	0.000
F17.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F17.6 Amnesic syndrome	0.005	0.995	0.000
F17.5 Psychotic disorder	0.005	0.995	0.000
F17.4 Withdrawal state with delirium	0.005	0.995	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.995	0.005
D44.4 Craniopharyngeal duct	0.005	0.995	0.000
F17.0 Acute intoxication	0.005	0.995	0.000
I44.5 Left posterior fascicular block	0.000	0.995	0.005
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.995	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.995	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.995	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.995	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.995	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.995	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.995	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.995	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.995	0.000
F17.9 Unspecified mental and behavioural disorder	0.004	0.995	0.000
R49.0 Dysphonia	0.000	0.995	0.005
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.004	0.996	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.996	0.004
I60 Subarachnoid haemorrhage	0.000	0.996	0.004
M84.04 Malunion of fracture (Hand)	0.004	0.996	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.004	0.996	0.000
T88.5 Other complications of anaesthesia	0.004	0.996	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.996	0.004
M84.07 Malunion of fracture (Ankle and foot)	0.004	0.996	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
K50.9 Crohn's disease, unspecified	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.000	0.996	0.004
T88.7 Unspecified adverse effect of drug or medicament	0.004	0.996	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.996	0.004
N75.0 Cyst of Bartholin's gland	0.004	0.996	0.000
I77.1 Stricture of artery	0.000	0.996	0.004
T88.9 Complication of surgical and medical care, unspecified	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.004	0.996	0.000
T88.2 Shock due to anaesthesia	0.004	0.996	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.996	0.004
M85.83 Other specified disorders of bone density and structure (Forearm)	0.004	0.996	0.000
T88.4 Failed or difficult intubation	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.997	0.003
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.997	0.003
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.997	0.003
I44.0 Atrioventricular block, first degree	0.000	0.997	0.003
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.003	0.997	0.000
T88.0 Infection following immunisation	0.003	0.997	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.997	0.003
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
M85.6 Other cyst of bone	0.003	0.997	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.997	0.003
K37 Unspecified appendicitis	0.003	0.997	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
F12.1 Harmful use	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
E11.4 With neurological complications	0.003	0.997	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.003	0.997	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.997	0.003
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
M85.68 Other cyst of bone (Other)	0.003	0.997	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.997	0.000
F12.2 Dependence syndrome	0.003	0.997	0.000
C02.1 Border of tongue	0.000	0.997	0.003
M85.2 Hyperostosis of skull	0.002	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.997	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.997	0.003
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.997	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.997	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
N35.9 Urethral stricture, unspecified	0.003	0.997	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.002	0.998	0.000
F12.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F12.8 Other mental and behavioural disorders	0.002	0.998	0.000
F12.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F12.6 Amnesic syndrome	0.002	0.998	0.000
F12.5 Psychotic disorder	0.002	0.998	0.000
F12.4 Withdrawal state with delirium	0.002	0.998	0.000
F12.3 Withdrawal state	0.002	0.998	0.000
F12.0 Acute intoxication	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.998	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
M83.80 Other adult osteomalacia (Multiple sites)	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
M81.8 Other osteoporosis	0.002	0.998	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.002
M85.20 Hyperostosis of skull-Mult sites	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.998	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.002	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.002	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.002	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.002	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.002	0.998	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.002	0.998	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.002	0.998	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.002	0.998	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.002	0.998	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.002	0.998	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.002	0.998	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.002	0.998	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.002	0.998	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.002	0.998	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.002	0.998	0.000
E03.9 Hypothyroidism, unspecified	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.002	0.998	0.000
K09 Cysts of oral region, not elsewhere classified	0.002	0.998	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.08 Puerperal osteomalacia (Other)	0.002	0.998	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.002	0.998	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.04 Puerperal osteomalacia (Hand)	0.002	0.998	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.002	0.998	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.002	0.998	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.002	0.998	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.002	0.998	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.002	0.998	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.002	0.998	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.002	0.998	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.002	0.998	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.002	0.998	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.002	0.998	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.002	0.998	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.002	0.998	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.002	0.998	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.002	0.998	0.000
M83.48 Aluminium bone disease (Other)	0.002	0.998	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.002	0.998	0.000
M83.46 Aluminium bone disease (Lower leg)	0.002	0.998	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.002	0.998	0.000
M83.44 Aluminium bone disease (Hand)	0.002	0.998	0.000
M83.43 Aluminium bone disease (Forearm)	0.002	0.998	0.000
M83.42 Aluminium bone disease (Upper arm)	0.002	0.998	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.002	0.998	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.002	0.998	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.002	0.998	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.002	0.998	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.002	0.998	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.002	0.998	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.002	0.998	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.002	0.998	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.002	0.998	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.002	0.998	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.002	0.998	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.002	0.998	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.002	0.998	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.002	0.998	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.002	0.998	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.002	0.998	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.002	0.998	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.002	0.998	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.002	0.998	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.002	0.998	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
F18 Mental and behavioural disorders due to use of volatile solvents	0.002	0.998	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.002	0.998	0.000
F19.1 Harmful use	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
H47.2 Optic atrophy	0.000	0.998	0.002
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.002	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.002	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.002	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.002	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.002	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.002	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.002	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.002	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.002	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.002	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.002	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.002	0.998	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
M93.1 Kienbock's disease of adults	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.002	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.002	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.002	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.002	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations