TreeWAS – Variant ID: rs4726279

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.982	0.018
R26 Abnormalities of gait and mobility	0.000	0.983	0.017
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.984	0.016
I08.0 Disorders of both mitral and aortic valves	0.016	0.984	0.000
R26.3 Immobility	0.000	0.985	0.015
R26.0 Ataxic gait	0.000	0.986	0.013
R26.1 Paralytic gait	0.000	0.988	0.012
A41.5 Septicaemia due to other Gram-negative organisms	0.012	0.988	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.012	0.988	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.988	0.012
A41 Other septicaemia	0.011	0.989	0.000
Q38.7 Pharyngeal pouch	0.010	0.990	0.000
A40.8 Other streptococcal septicaemia	0.010	0.990	0.000
S80.0 Contusion of knee	0.010	0.990	0.000
A40 Streptococcal septicaemia	0.009	0.991	0.000
A30-A49 Other bacterial diseases	0.009	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.008	0.992	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
A48 Other bacterial diseases, not elsewhere classified	0.008	0.992	0.000
A41.4 Septicaemia due to anaerobes	0.008	0.992	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.008	0.992	0.000
S42.00 Fracture of clavicle (closed)	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.007	0.992	0.000
A48.1 Legionnaires' disease	0.007	0.993	0.000
A40.0 Septicaemia due to streptococcus, group A	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.007	0.993	0.000
T40.2 Other opioids	0.007	0.993	0.000
T39.0 Salicylates	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
A40.2 Septicaemia due to streptococcus, group D	0.007	0.993	0.000
A31 Infection due to other mycobacteria	0.007	0.993	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.007	0.993	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.007	0.993	0.000
T42.4 Benzodiazepines	0.007	0.993	0.000
A40.1 Septicaemia due to streptococcus, group B	0.007	0.993	0.000
A44 Bartonellosis	0.006	0.993	0.000
A43 Nocardiosis	0.006	0.993	0.000
A42 Actinomycosis	0.006	0.993	0.000
A37 Whooping cough	0.006	0.993	0.000
A36 Diphtheria	0.006	0.993	0.000
A32 Listeriosis	0.006	0.993	0.000
A30 Leprosy [Hansen's disease]	0.006	0.993	0.000
A38 Scarlet fever	0.006	0.993	0.000
A35 Other tetanus	0.006	0.993	0.000
A34 Obstetrical tetanus	0.006	0.993	0.000
A33 Tetanus neonatorum	0.006	0.993	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
A39 Meningococcal infection	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
A48.8 Other specified bacterial diseases	0.006	0.994	0.000
A40.9 Streptococcal septicaemia, unspecified	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
A48.4 Brazilian purpuric fever	0.006	0.994	0.000
A48.3 Toxic shock syndrome	0.006	0.994	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.006	0.994	0.000
A48.0 Gas gangrene	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.3 Barbiturates	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
A49 Bacterial infection of unspecified site	0.006	0.994	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.006	0.994	0.000
A49.8 Other bacterial infections of unspecified site	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
G83.4 Cauda equina syndrome	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.994	0.000
T40.8 Lysergide [LSD]	0.006	0.994	0.000
T40.7 Cannabis (derivatives)	0.006	0.994	0.000
T40.5 Cocaine	0.006	0.994	0.000
T40.3 Methadone	0.006	0.994	0.000
T40.1 Heroin	0.006	0.994	0.000
T40.0 Opium	0.006	0.994	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.006	0.994	0.000
Q38.8 Other congenital malformations of pharynx	0.006	0.994	0.000
A31.0 Pulmonary mycobacterial infection	0.005	0.994	0.000
T42.1 Iminostilbenes	0.005	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T17 Foreign body in respiratory tract	0.005	0.995	0.000
Q38.6 Other congenital malformations of mouth	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
A31.9 Mycobacterial infection, unspecified	0.005	0.995	0.000
A31.8 Other mycobacterial infections	0.005	0.995	0.000
A31.1 Cutaneous mycobacterial infection	0.005	0.995	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.995	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.005	0.995	0.000
Q38.3 Other congenital malformations of tongue	0.005	0.995	0.000
Q38.2 Macroglossia	0.005	0.995	0.000
Q38.1 Ankyloglossia	0.005	0.995	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
A39.4 Meningococcaemia, unspecified	0.005	0.995	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.005	0.995	0.000
A30.9 Leprosy, unspecified	0.005	0.995	0.000
A30.8 Other forms of leprosy	0.005	0.995	0.000
A30.5 Lepromatous leprosy	0.005	0.995	0.000
A30.4 Borderline lepromatous leprosy	0.005	0.995	0.000
A30.3 Borderline leprosy	0.005	0.995	0.000
A30.2 Borderline tuberculoid leprosy	0.005	0.995	0.000
A30.1 Tuberculoid leprosy	0.005	0.995	0.000
A30.0 Indeterminate leprosy	0.005	0.995	0.000
A32.9 Listeriosis, unspecified	0.005	0.995	0.000
A32.8 Other forms of listeriosis	0.005	0.995	0.000
A32.7 Listerial septicaemia	0.005	0.995	0.000
A32.1 Listerial meningitis and meningoencephalitis	0.005	0.995	0.000
A32.0 Cutaneous listeriosis	0.005	0.995	0.000
A36.9 Diphtheria, unspecified	0.005	0.995	0.000
A36.8 Other diphtheria	0.005	0.995	0.000
A36.3 Cutaneous diphtheria	0.005	0.995	0.000
A36.2 Laryngeal diphtheria	0.005	0.995	0.000
A36.1 Nasopharyngeal diphtheria	0.005	0.995	0.000
A36.0 Pharyngeal diphtheria	0.005	0.995	0.000
A37.9 Whooping cough, unspecified	0.005	0.995	0.000
A37.8 Whooping cough due to other Bordetella species	0.005	0.995	0.000
A37.1 Whooping cough due to Bordetella parapertussis	0.005	0.995	0.000
A37.0 Whooping cough due to Bordetella pertussis	0.005	0.995	0.000
A42.9 Actinomycosis, unspecified	0.005	0.995	0.000
A42.8 Other forms of actinomycosis	0.005	0.995	0.000
A42.7 Actinomycotic septicaemia	0.005	0.995	0.000
A42.2 Cervicofacial actinomycosis	0.005	0.995	0.000
A42.1 Abdominal actinomycosis	0.005	0.995	0.000
A42.0 Pulmonary actinomycosis	0.005	0.995	0.000
A43.9 Nocardiosis, unspecified	0.005	0.995	0.000
A43.8 Other forms of nocardiosis	0.005	0.995	0.000
A43.1 Cutaneous nocardiosis	0.005	0.995	0.000
A43.0 Pulmonary nocardiosis	0.005	0.995	0.000
A44.9 Bartonellosis, unspecified	0.005	0.995	0.000
A44.8 Other forms of bartonellosis	0.005	0.995	0.000
A44.1 Cutaneous and mucocutaneous bartonellosis	0.005	0.995	0.000
A44.0 Systemic bartonellosis	0.005	0.995	0.000
J04.0 Acute laryngitis	0.005	0.995	0.000
T36.0 Penicillins	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T17.3 Foreign body in larynx	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
A39.9 Meningococcal infection, unspecified	0.005	0.995	0.000
A39.8 Other meningococcal infections	0.005	0.995	0.000
A39.5 Meningococcal heart disease	0.005	0.995	0.000
A39.3 Chronic meningococcaemia	0.005	0.995	0.000
A39.2 Acute meningococcaemia	0.005	0.995	0.000
A39.1 Waterhouse-Friderichsen syndrome	0.005	0.995	0.000
H02.3 Blepharochalasis	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.005	0.995	0.000
T17.2 Foreign body in pharynx	0.005	0.995	0.000
T17.5 Foreign body in bronchus	0.005	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.995	0.000
T37.5 Antiviral drugs	0.004	0.995	0.000
T37.4 Anthelminthics	0.004	0.995	0.000
T37.3 Other antiprotozoal drugs	0.004	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.995	0.000
T37.1 Antimycobacterial drugs	0.004	0.995	0.000
T37.0 Sulphonamides	0.004	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.995	0.000
T44.0 Anticholinesterase agents	0.004	0.995	0.000
A49.3 Mycoplasma infection, unspecified	0.004	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.995	0.000
T50.5 Appetite depressants	0.004	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.995	0.000
T41.5 Therapeutic gases	0.004	0.995	0.000
T41.4 Anaesthetic, unspecified	0.004	0.995	0.000
T41.3 Local anaesthetics	0.004	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.995	0.000
T41.1 Intravenous anaesthetics	0.004	0.995	0.000
T41.0 Inhaled anaesthetics	0.004	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.995	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.996	0.004
G58.8 Other specified mononeuropathies	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
A49.0 Staphylococcal infection, unspecified	0.004	0.996	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.004	0.996	0.000
A39.0 Meningococcal meningitis	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.004	0.996	0.000
S42.0 Fracture of clavicle	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
I84.0 Internal thrombosed haemorrhoids	0.000	0.996	0.004
T17.4 Foreign body in trachea	0.004	0.996	0.000
T17.1 Foreign body in nostril	0.004	0.996	0.000
T17.0 Foreign body in nasal sinus	0.004	0.996	0.000
A41.8 Other specified septicaemia	0.004	0.996	0.000
A46 Erysipelas	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.004	0.996	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.004	0.996	0.000
I22.8 Subsequent myocardial infarction of other sites	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
R44.3 Hallucinations, unspecified	0.004	0.996	0.000
S91.0 Open wound of ankle	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.996	0.004
S80 Superficial injury of lower leg	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
S82.81 Fractures of other parts of lower leg (open)	0.004	0.996	0.000
G58 Other mononeuropathies	0.004	0.996	0.000
G58.9 Mononeuropathy, unspecified	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
I22 Subsequent myocardial infarction	0.004	0.996	0.000
W13.9 Unspecified place	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.996	0.000
T45.4 Iron and its compounds	0.003	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.996	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
T18 Foreign body in alimentary tract	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
S42.01 Fracture of clavicle (open)	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
A49.1 Streptococcal infection, unspecified	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.003	0.997	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
G58.0 Intercostal neuropathy	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.997	0.003
I22.0 Subsequent myocardial infarction of anterior wall	0.003	0.997	0.000
T18.0 Foreign body in mouth	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
T18.5 Foreign body in anus and rectum	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
Z90.5 Acquired absence of kidney	0.003	0.997	0.000
G58.7 Mononeuritis multiplex	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
L28.0 Lichen simplex chronicus	0.000	0.997	0.003
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.003	0.997	0.000
T79.7 Traumatic subcutaneous emphysema	0.003	0.997	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
T19 Foreign body in genito-urinary tract	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
T79-T79 Certain early complications of trauma	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.003	0.997	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.003	0.997	0.000
T18.4 Foreign body in colon	0.003	0.997	0.000
T18.3 Foreign body in small intestine	0.003	0.997	0.000
T18.2 Foreign body in stomach	0.003	0.997	0.000
Z36 Antenatal screening	0.003	0.997	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.997	0.003
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.997	0.000
T88.5 Other complications of anaesthesia	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.003	0.997	0.000
S93.4 Sprain and strain of ankle	0.002	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.002	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.003	0.997	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.997	0.000
T15.9 Foreign body on external eye, unspecified	0.002	0.997	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.002	0.997	0.000
T15.1 Foreign body in conjunctival sac	0.002	0.997	0.000
T15.0 Foreign body in cornea	0.002	0.997	0.000
S92.51 Fracture of other toe (open)	0.002	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.997	0.000
S92.4 Fracture of great toe	0.002	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.997	0.000
G83 Other paralytic syndromes	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
T01 Open wounds involving multiple body regions	0.002	0.997	0.000
T68 Hypothermia	0.002	0.997	0.000
R60.9 Oedema, unspecified	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
C92 Myeloid leukaemia	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.997	0.000
G54.0 Brachial plexus disorders	0.002	0.997	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.997	0.000
C43 Malignant melanoma of skin	0.000	0.997	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.997	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.001
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
S19.8 Other specified injuries of neck	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.002	0.998	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.002	0.998	0.000
J04 Acute laryngitis and tracheitis	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.002	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
T00 Superficial injuries involving multiple body regions	0.002	0.998	0.000
T33-T35 Frostbite	0.002	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.002	0.998	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.002	0.998	0.000
T19.3 Foreign body in uterus [any part]	0.002	0.998	0.000
T19.0 Foreign body in urethra	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.998	0.002
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.998	0.002
T01.3 Open wounds involving multiple regions of lower limb(s)	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
T19.1 Foreign body in bladder	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.002	0.998	0.000
T05 Traumatic amputations involving multiple body regions	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations