TreeWAS – Variant ID: rs4727338

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.9 Osteoporosis, unspecified	0.000	0.633	0.367
M81 Osteoporosis without pathological fracture	0.000	0.638	0.362
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.642	0.358
M80-M85 Disorders of bone density and structure	0.000	0.646	0.354
M85 Other disorders of bone density and structure	0.000	0.655	0.345
M80 Osteoporosis with pathological fracture	0.000	0.658	0.342
M85.8 Other specified disorders of bone density and structure	0.000	0.662	0.338
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.666	0.334
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.672	0.328
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.682	0.318
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.685	0.315
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.694	0.306
M81.2 Osteoporosis of disuse	0.000	0.696	0.304
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.703	0.297
M81.4 Drug-induced osteoporosis	0.000	0.706	0.294
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.711	0.289
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.712	0.288
M85.6 Other cyst of bone	0.000	0.715	0.285
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.717	0.283
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.722	0.278
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.723	0.277
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.726	0.274
M85.2 Hyperostosis of skull	0.000	0.731	0.269
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.737	0.263
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.737	0.263
M80.8 Other osteoporosis with pathological fracture	0.000	0.737	0.263
M81.1 Postoophorectomy osteoporosis	0.000	0.740	0.260
M81.6 Localised osteoporosis [Lequesne]	0.000	0.740	0.260
M81.5 Idiopathic osteoporosis	0.000	0.740	0.260
M81.98 Osteoporosis, unspecified (Other)	0.000	0.741	0.259
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.744	0.256
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.746	0.254
M85.5 Aneurysmal bone cyst	0.000	0.752	0.248
M85.3 Osteitis condensans	0.000	0.752	0.248
M85.1 Skeletal fluorosis	0.000	0.752	0.248
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.754	0.246
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.754	0.246
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.754	0.246
M85.0 Fibrous dysplasia (monostotic)	0.000	0.755	0.245
M85.68 Other cyst of bone (Other)	0.000	0.757	0.242
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.758	0.242
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.758	0.242
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.759	0.241
M84 Disorders of continuity of bone	0.000	0.760	0.240
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.760	0.240
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.762	0.237
M82 Osteoporosis in diseases classified elsewhere	0.000	0.763	0.237
M81.0 Postmenopausal osteoporosis	0.000	0.763	0.237
M85.64 Other cyst of bone (Hand)	0.000	0.763	0.237
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.765	0.235
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.765	0.235
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.765	0.235
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.765	0.235
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.765	0.235
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.765	0.235
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.765	0.235
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.765	0.235
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.765	0.235
M83 Adult osteomalacia	0.000	0.765	0.235
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.765	0.235
M85.9 Disorder of bone density and structure, unspecified	0.000	0.768	0.232
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.770	0.230
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.773	0.226
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.774	0.226
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.775	0.225
M81.8 Other osteoporosis	0.000	0.777	0.222
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.777	0.222
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.778	0.222
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.782	0.218
M81.28 Osteoporosis of disuse (Other)	0.000	0.782	0.218
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.782	0.218
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.782	0.218
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.782	0.218
M81.24 Osteoporosis of disuse (Hand)	0.000	0.782	0.218
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.782	0.218
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.782	0.218
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.782	0.218
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.782	0.218
M85.66 Other cyst of bone (Lower leg)	0.000	0.786	0.214
M81.48 Drug-induced osteoporosis (Other)	0.000	0.789	0.211
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.789	0.211
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.789	0.211
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.789	0.211
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.789	0.211
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.789	0.211
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.789	0.211
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.789	0.211
M85.20 Hyperostosis of skull-Mult sites	0.000	0.791	0.208
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.792	0.208
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.792	0.208
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.792	0.208
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.792	0.208
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.792	0.208
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.792	0.208
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.792	0.208
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.792	0.208
M85.4 Solitary bone cyst	0.000	0.793	0.206
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.795	0.204
M85.69 Other cyst of bone (Site unspecified)	0.000	0.795	0.204
M85.63 Other cyst of bone (Forearm)	0.000	0.795	0.204
M85.62 Other cyst of bone (Upper arm)	0.000	0.795	0.204
M85.61 Other cyst of bone (Shoulder region)	0.000	0.795	0.204
M85.60 Other cyst of bone (Multiple sites)	0.000	0.795	0.204
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.797	0.203
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.797	0.203
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.797	0.203
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.797	0.203
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.797	0.203
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.797	0.203
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.797	0.203
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.797	0.203
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.797	0.203
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.797	0.202
M85.22 Hyperostosis of skull-Upper arm	0.000	0.798	0.201
M85.29 Hyperostosis of skull-Site unspec	0.000	0.807	0.193
M85.28 Hyperostosis of skull-Other	0.000	0.807	0.193
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.807	0.193
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.807	0.193
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.807	0.193
M85.24 Hyperostosis of skull-Hand	0.000	0.807	0.193
M85.23 Hyperostosis of skull-Forearm	0.000	0.807	0.193
M85.21 Hyperostosis of skull-Shldr region	0.000	0.807	0.193
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.807	0.193
M84.8 Other disorders of continuity of bone	0.000	0.807	0.193
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.807	0.192
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.811	0.188
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.811	0.188
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.811	0.188
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.811	0.188
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.811	0.188
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.811	0.188
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.811	0.188
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.811	0.188
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.813	0.187
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.813	0.187
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.813	0.187
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.813	0.187
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.813	0.187
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.813	0.187
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.813	0.187
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.813	0.187
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.813	0.187
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.813	0.187
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.813	0.187
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.813	0.186
M81.58 Idiopathic osteoporosis (Other)	0.000	0.813	0.186
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.813	0.186
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.813	0.186
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.813	0.186
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.813	0.186
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.813	0.186
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.813	0.186
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.813	0.186
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.813	0.186
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.813	0.186
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.813	0.186
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.813	0.186
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.813	0.186
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.813	0.186
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.813	0.186
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.813	0.186
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.813	0.186
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.813	0.186
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.813	0.186
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.816	0.184
M84.3 Stress fracture, not elsewhere classified	0.000	0.817	0.182
M83.8 Other adult osteomalacia	0.000	0.818	0.182
M84.0 Malunion of fracture	0.000	0.822	0.178
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.822	0.178
M85.18 Skeletal fluorosis (Other)	0.000	0.822	0.178
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.822	0.178
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.822	0.178
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.822	0.178
M85.14 Skeletal fluorosis (Hand)	0.000	0.822	0.178
M85.13 Skeletal fluorosis (Forearm)	0.000	0.822	0.178
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.822	0.178
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.822	0.178
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.822	0.178
M85.39 Osteitis condensans (Site unspecified)	0.000	0.822	0.178
M85.38 Osteitis condensans (Other)	0.000	0.822	0.178
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.822	0.178
M85.36 Osteitis condensans (Lower leg)	0.000	0.822	0.178
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.822	0.178
M85.34 Osteitis condensans (Hand)	0.000	0.822	0.178
M85.33 Osteitis condensans (Forearm)	0.000	0.822	0.178
M85.32 Osteitis condensans (Upper arm)	0.000	0.822	0.178
M85.31 Osteitis condensans (Shoulder region)	0.000	0.822	0.178
M85.30 Osteitis condensans (Multiple sites)	0.000	0.822	0.178
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.822	0.178
M85.58 Aneurysmal bone cyst (Other)	0.000	0.822	0.178
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.822	0.178
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.822	0.178
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.822	0.178
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.822	0.178
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.822	0.178
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.822	0.178
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.822	0.178
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.822	0.178
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.824	0.176
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.824	0.176
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.824	0.176
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.824	0.176
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.824	0.176
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.824	0.176
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.824	0.176
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.824	0.176
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.824	0.176
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.824	0.176
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.824	0.176
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.824	0.176
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.824	0.176
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.824	0.176
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.824	0.176
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.824	0.176
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.824	0.176
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.824	0.176
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.824	0.176
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.824	0.176
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.824	0.176
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.824	0.176
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.824	0.176
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.824	0.176
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.824	0.176
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.824	0.176
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.824	0.176
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.824	0.176
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.824	0.176
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.824	0.176
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.824	0.176
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.824	0.176
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.824	0.176
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.824	0.176
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.824	0.176
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.824	0.176
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.824	0.176
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.824	0.176
M84.2 Delayed union of fracture	0.000	0.825	0.175
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.825	0.175
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.827	0.173
M84.9 Disorder of continuity of bone, unspecified	0.000	0.827	0.172
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.828	0.172
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.828	0.172
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.828	0.172
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.828	0.172
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.828	0.172
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.828	0.172
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.830	0.170
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.830	0.170
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.830	0.170
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.830	0.170
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.830	0.170
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.830	0.170
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.830	0.170
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.830	0.170
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.830	0.170
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.830	0.170
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.830	0.170
M83.5 Other drug-induced osteomalacia in adults	0.000	0.831	0.169
M83.4 Aluminum bone disease	0.000	0.831	0.169
M83.2 Adult osteomalacia due to malabsorption	0.000	0.831	0.169
M83.0 Puerperal osteomalacia	0.000	0.831	0.169
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.833	0.167
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.833	0.166
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.833	0.166
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.833	0.166
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.833	0.166
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.833	0.166
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.833	0.166
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.833	0.166
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.834	0.165
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.836	0.164
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.838	0.162
M81.88 Other osteoporosis (Other)	0.000	0.840	0.159
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.840	0.159
M81.86 Other osteoporosis (Lower leg)	0.000	0.840	0.159
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.840	0.159
M81.84 Other osteoporosis (Hand)	0.000	0.840	0.159
M81.83 Other osteoporosis (Forearm)	0.000	0.840	0.159
M81.82 Other osteoporosis (Upper arm)	0.000	0.840	0.159
M81.81 Other osteoporosis (Shoulder region)	0.000	0.840	0.159
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.840	0.160
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.840	0.160
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.840	0.160
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.840	0.160
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.840	0.160
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.840	0.160
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.840	0.160
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.840	0.160
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.840	0.160
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.841	0.159
M83.1 Senile osteomalacia	0.000	0.842	0.158
M83.9 Adult osteomalacia, unspecified	0.000	0.842	0.158
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.842	0.158
M83.3 Adult osteomalacia due to malnutrition	0.000	0.844	0.156
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.844	0.156
M82.1 Osteoporosis in endocrine disorders	0.000	0.846	0.154
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.847	0.153
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.852	0.148
M85.48 Solitary bone cyst (Other)	0.000	0.852	0.148
M85.44 Solitary bone cyst (Hand)	0.000	0.852	0.148
M85.43 Solitary bone cyst (Forearm)	0.000	0.852	0.148
M85.42 Solitary bone cyst (Upper arm)	0.000	0.852	0.148
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.852	0.148
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.852	0.148
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.853	0.147
M81.89 Other osteoporosis (Site unspecified)	0.000	0.856	0.144
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.856	0.144
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.856	0.144
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.857	0.143
M81.80 Other osteoporosis (Multiple sites)	0.000	0.858	0.142
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.858	0.141
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.859	0.141
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.860	0.140
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.861	0.138
M84.88 Other disorders of continuity of bone (Other)	0.000	0.861	0.138
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.861	0.138
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.861	0.138
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.861	0.138
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.861	0.138
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.861	0.138
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.861	0.138
M85.46 Solitary bone cyst (Lower leg)	0.000	0.862	0.138
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.862	0.138
M84.03 Malunion of fracture (Forearm)	0.000	0.863	0.137
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.863	0.136
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.867	0.133
M84.26 Delayed union of fracture (Lower leg)	0.000	0.867	0.133
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.868	0.132
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.868	0.132
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.869	0.131
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.869	0.131
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.869	0.131
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.869	0.131
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.869	0.131
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.869	0.131
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.869	0.131
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.869	0.131
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.869	0.131
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.869	0.131
M83.88 Other adult osteomalacia (Other)	0.000	0.869	0.131
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.869	0.131
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.869	0.131
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.869	0.131
M83.84 Other adult osteomalacia (Hand)	0.000	0.869	0.131
M83.83 Other adult osteomalacia (Forearm)	0.000	0.869	0.131
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.869	0.131
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.869	0.131
M84.09 Malunion of fracture (Site unspecified)	0.000	0.872	0.128
M84.00 Malunion of fracture (Multiple sites)	0.000	0.872	0.128
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.873	0.127
M84.4 Pathological fracture, not elsewhere classified	0.000	0.874	0.126
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.874	0.126
M84.28 Delayed union of fracture (Other)	0.000	0.874	0.126
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.874	0.126
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.874	0.126
M84.24 Delayed union of fracture (Hand)	0.000	0.874	0.126
M84.23 Delayed union of fracture (Forearm)	0.000	0.874	0.126
M84.22 Delayed union of fracture (Upper arm)	0.000	0.874	0.126
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.874	0.126
M84.08 Malunion of fracture (Other)	0.000	0.874	0.126
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.876	0.124
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.876	0.124
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.876	0.124
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.876	0.124
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.876	0.124
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.876	0.124
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.876	0.124
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.876	0.124
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.876	0.124
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.876	0.124
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.000	0.878	0.122
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.000	0.878	0.122
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.000	0.878	0.122
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.000	0.878	0.122
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.000	0.878	0.122
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.000	0.878	0.122
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.000	0.878	0.122
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.000	0.878	0.122
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.000	0.878	0.122
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.000	0.878	0.122
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.000	0.878	0.122
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.000	0.878	0.122
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.000	0.878	0.122
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.000	0.878	0.122
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.000	0.878	0.122
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.000	0.878	0.122
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.000	0.878	0.122
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.000	0.878	0.122
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.000	0.878	0.122
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.000	0.878	0.122
M84.06 Malunion of fracture (Lower leg)	0.000	0.878	0.122
M84.04 Malunion of fracture (Hand)	0.000	0.878	0.122
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.879	0.121
M83.08 Puerperal osteomalacia (Other)	0.000	0.879	0.121
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.879	0.121
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.879	0.121
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.879	0.121
M83.04 Puerperal osteomalacia (Hand)	0.000	0.879	0.121
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.879	0.121
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.879	0.121
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.879	0.121
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.879	0.121
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.879	0.121
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.879	0.121
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.879	0.121
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.879	0.121
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.879	0.121
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.879	0.121
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.879	0.121
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.879	0.121
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.879	0.121
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.879	0.121
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.879	0.121
M83.48 Aluminium bone disease (Other)	0.000	0.879	0.121
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.879	0.121
M83.46 Aluminium bone disease (Lower leg)	0.000	0.879	0.121
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.879	0.121
M83.44 Aluminium bone disease (Hand)	0.000	0.879	0.121
M83.43 Aluminium bone disease (Forearm)	0.000	0.879	0.121
M83.42 Aluminium bone disease (Upper arm)	0.000	0.879	0.121
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.879	0.121
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.879	0.121
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.879	0.121
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.879	0.121
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.879	0.121
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.879	0.121
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.879	0.121
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.879	0.121
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.879	0.121
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.879	0.121
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.879	0.121
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.879	0.121
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.879	0.121
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.886	0.113
M83.18 Senile osteomalacia (Other)	0.000	0.886	0.113
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.886	0.113
M83.16 Senile osteomalacia (Lower leg)	0.000	0.886	0.113
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.886	0.113
M83.14 Senile osteomalacia (Hand)	0.000	0.886	0.113
M83.13 Senile osteomalacia (Forearm)	0.000	0.886	0.113
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.886	0.113
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.886	0.113
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.886	0.113
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.886	0.113
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.886	0.113
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.886	0.113
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.886	0.113
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.886	0.113
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.886	0.113
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.886	0.113
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.886	0.113
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.888	0.112
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.888	0.112
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.888	0.112
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.888	0.112
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.888	0.112
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.888	0.112
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.888	0.112
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.888	0.112
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.888	0.112
M84.01 Malunion of fracture (Shoulder region)	0.000	0.889	0.111
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.889	0.110
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.889	0.110
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.889	0.110
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.889	0.110
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.889	0.110
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.889	0.110
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.889	0.110
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.889	0.110
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.891	0.109
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.894	0.106
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.894	0.106
M83.12 Senile osteomalacia (Upper arm)	0.000	0.897	0.103
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.897	0.102
M84.02 Malunion of fracture (Upper arm)	0.000	0.897	0.102
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.900	0.100
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.903	0.097
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.904	0.096
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.905	0.095
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.908	0.092
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.909	0.090
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.909	0.090
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.909	0.090
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.909	0.090
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.909	0.090
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.910	0.090
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.911	0.089
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.912	0.088
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.913	0.087
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.922	0.078
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.931	0.069
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.936	0.063
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.939	0.061
E04.1 Non-toxic single thyroid nodule	0.023	0.977	0.000
E04.9 Non-toxic goitre, unspecified	0.022	0.978	0.000
E04 Other non-toxic goitre	0.019	0.981	0.000
O14.9 Preeclampsia, unspecified	0.000	0.982	0.018
K72.9 Hepatic failure, unspecified	0.018	0.982	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.983	0.017
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.983	0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations