TreeWAS – Variant ID: rs473238

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.061	0.939
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.068	0.932
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.070	0.930
T50.9 Other and unspecified drugs, medicaments and biological substances	0.077	0.923
T43.2 Other and unspecified antidepressants	0.097	0.903
T46 Poisoning by agents primarily affecting the cardiovascular system	0.119	0.881
T46.4 Angiotensin-converting-enzyme inhibitors	0.166	0.834
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.186	0.814
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.186	0.814
T43.0 Tricyclic and tetracyclic antidepressants	0.189	0.811
T43.5 Other and unspecified antipsychotics and neuroleptics	0.194	0.806
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.223	0.777
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.237	0.763
T47.1 Other antacids and anti-gastric-secretion drugs	0.249	0.751
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.261	0.739
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.262	0.738
T50.6 Antidotes and chelating agents, not elsewhere classified	0.268	0.732
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.275	0.725
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.282	0.718
T43.4 Butyrophenone and thioxanthene neuroleptics	0.284	0.716
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.302	0.698
T50.1 Loop [high-ceiling] diuretics	0.303	0.697
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.304	0.696
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.312	0.688
T50.4 Drugs affecting uric acid metabolism	0.314	0.686
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.321	0.679
T43.6 Psychostimulants with abuse potential	0.324	0.676
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.325	0.675
T43.8 Other psychotropic drugs, not elsewhere classified	0.332	0.668
T46.3 Coronary vasodilators, not elsewhere classified	0.333	0.667
T50.7 Analeptics and opioid receptor antagonists	0.333	0.667
T50.5 Appetite depressants	0.333	0.667
T50.3 Electrolytic, caloric and water-balance agents	0.333	0.667
T50.0 Mineralocorticoids and their antagonists	0.333	0.667
T42.3 Barbiturates	0.338	0.661
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.354	0.646
T41 Poisoning by anaesthetics and therapeutic gases	0.357	0.643
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.361	0.639
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.364	0.635
T46.8 Antivaricose drugs, including sclerosing agents	0.368	0.632
T46.7 Peripheral vasodilators	0.368	0.632
T50.8 Diagnostic agents	0.369	0.631
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.379	0.621
T36 Poisoning by systemic antibiotics	0.384	0.616
T43.3 Phenothiazine antipsychotics and neuroleptics	0.386	0.614
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.390	0.610
T46.5 Other antihypertensive drugs, not elsewhere classified	0.392	0.608
T43.9 Psychotropic drug, unspecified	0.393	0.607
T40.2 Other opioids	0.395	0.605
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.395	0.605
T46.1 Calcium-channel blockers	0.397	0.603
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.397	0.602
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.398	0.602
T42.0 Hydantoin derivatives	0.400	0.600
T40.5 Cocaine	0.405	0.594
T45.2 Vitamins, not elsewhere classified	0.408	0.592
T47.4 Other laxatives	0.409	0.590
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.415	0.585
T47.0 Histamine H(2)-receptor antagonists	0.415	0.585
T45.1 Antineoplastic and immunosuppressive drugs	0.415	0.585
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.416	0.584
T47.8 Other agents primarily affecting the gastro-intestinal system	0.416	0.584
T47.7 Emetics	0.416	0.584
T47.5 Digestants	0.416	0.584
T47.3 Saline and osmotic laxatives	0.416	0.584
T42.5 Mixed antiepileptics, not elsewhere classified	0.417	0.583
T42.2 Succinimides and oxazolidinediones	0.417	0.583
T45.0 Antiallergic and antiemetic drugs	0.422	0.578
T38.0 Glucocorticoids and synthetic analogues	0.427	0.573
T40.1 Heroin	0.428	0.572
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.430	0.570
T39.4 Antirheumatics, not elsewhere classified	0.443	0.557
T39.2 Pyrazolone derivatives	0.443	0.557
T47.6 Antidiarrhoeal drugs	0.444	0.556
T42.4 Benzodiazepines	0.446	0.554
T45.9 Primarily systemic and haematological agent, unspecified	0.453	0.547
T45.8 Other primarily systemic and haematological agents	0.453	0.547
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.453	0.547
T45.6 Fibrinolysis-affecting drugs	0.453	0.547
T45.4 Iron and its compounds	0.453	0.547
T45.3 Enzymes, not elsewhere classified	0.453	0.547
T38.5 Other oestrogens and progestogens	0.461	0.539
T45.5 Anticoagulants	0.463	0.537
T38.8 Other and unspecified hormones and their synthetic substitutes	0.464	0.536
T38.1 Thyroid hormones and substitutes	0.470	0.530
T38.9 Other and unspecified hormone antagonists	0.470	0.530
T38.7 Androgens and anabolic congeners	0.470	0.530
T38.4 Oral contraceptives	0.470	0.530
T38.2 Antithyroid drugs	0.470	0.530
T48.5 Anti-common-cold drugs	0.470	0.530
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.474	0.526
T39.0 Salicylates	0.475	0.525
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.480	0.520
T40.8 Lysergide [LSD]	0.480	0.520
T40.7 Cannabis (derivatives)	0.480	0.520
T40.0 Opium	0.480	0.520
T47.2 Stimulant laxatives	0.481	0.519
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.487	0.513
T42.1 Iminostilbenes	0.490	0.510
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.491	0.509
T40.3 Methadone	0.499	0.501
T49.9 Topical agent, unspecified	0.499	0.501
T49.8 Other topical agents	0.499	0.501
T49.7 Dental drugs, topically applied	0.499	0.501
T49.6 Otorhinolaryngological drugs and preparations	0.499	0.501
T49.5 Ophthalmological drugs and preparations	0.499	0.501
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.499	0.501
T49.3 Emollients, demulcents and protectants	0.499	0.501
T49.2 Local astringents and local detergents	0.499	0.501
T49.1 Antipruritics	0.499	0.501
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.501	0.499
T48.4 Expectorants	0.501	0.499
T48.3 Antitussives	0.501	0.499
T48.2 Other and unspecified agents primarily acting on muscles	0.501	0.499
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.501	0.499
T48.0 Oxytocic drugs	0.501	0.499
T48.6 Antiasthmatics, not elsewhere classified	0.511	0.489
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.513	0.487
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.513	0.487
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.513	0.487
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.513	0.487
T44.1 Other parasympathomimetics [cholinergics]	0.513	0.487
T44.0 Anticholinesterase agents	0.513	0.487
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.517	0.483
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.524	0.476
T41.5 Therapeutic gases	0.539	0.461
T41.4 Anaesthetic, unspecified	0.539	0.461
T41.3 Local anaesthetics	0.539	0.461
T41.1 Intravenous anaesthetics	0.539	0.461
T41.0 Inhaled anaesthetics	0.539	0.461
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.541	0.458
T37.5 Antiviral drugs	0.541	0.458
T37.4 Anthelminthics	0.541	0.458
T37.3 Other antiprotozoal drugs	0.541	0.458
T37.1 Antimycobacterial drugs	0.541	0.458
T37.0 Sulphonamides	0.541	0.458
T36.4 Tetracyclines	0.547	0.453
T36.3 Macrolides	0.553	0.447
T37.2 Antimalarials and drugs acting on other blood protozoa	0.557	0.442
T37.8 Other specified systemic anti-infectives and antiparasitics	0.558	0.442
T36.9 Systemic antibiotic, unspecified	0.558	0.442
T36.7 Antifungal antibiotics, systemically used	0.558	0.442
T36.6 Rifamycins	0.558	0.442
T36.5 Aminoglycosides	0.558	0.442
T36.2 Chloramphenicol group	0.558	0.442
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.558	0.442
T39.1 4-Aminophenol derivatives	0.562	0.438
T41.2 Other and unspecified general anaesthetics	0.569	0.431
T36.8 Other systemic antibiotics	0.574	0.426
T40.6 Other and unspecified narcotics	0.577	0.423
T36.0 Penicillins	0.583	0.417
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.588	0.412
T40.4 Other synthetic narcotics	0.616	0.384
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.718	0.282
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.718	0.282
T18 Foreign body in alimentary tract	0.719	0.281
T15-T19 Effects of foreign body entering through natural orifice	0.720	0.280
T18.1 Foreign body in oesophagus	0.720	0.280
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.720	0.280
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.727	0.273
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.739	0.261
S60-S69 Injuries to the wrist and hand	0.743	0.257
T00-T07 Injuries involving multiple body regions	0.744	0.256
S60 Superficial injury of wrist and hand	0.751	0.249
T80 Complications following infusion, transfusion and therapeutic injection	0.752	0.248
T86 Failure and rejection of transplanted organs and tissues	0.752	0.248
S90-S99 Injuries to the ankle and foot	0.754	0.246
T85 Complications of other internal prosthetic devices, implants and grafts	0.755	0.245
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.761	0.239
S60.9 Superficial injury of wrist and hand, unspecified	0.767	0.233
T87 Complications peculiar to reattachment and amputation	0.769	0.231
S64 Injury of nerves at wrist and hand level	0.770	0.230
T00 Superficial injuries involving multiple body regions	0.771	0.229
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.774	0.226
T18.0 Foreign body in mouth	0.774	0.226
T16 Foreign body in ear	0.777	0.223
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.778	0.222
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.785	0.215
S96 Injury of muscle and tendon at ankle and foot level	0.788	0.212
S62 Fracture at wrist and hand level	0.790	0.210
T86.8 Failure and rejection of other transplanted organs and tissues	0.790	0.210
T83.0 Mechanical complication of urinary (indwelling) catheter	0.791	0.209
T18.9 Foreign body in alimentary tract, part unspecified	0.792	0.208
T18.3 Foreign body in small intestine	0.792	0.208
T83.2 Mechanical complication of graft of urinary organ	0.792	0.208
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.795	0.205
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.795	0.205
T18.5 Foreign body in anus and rectum	0.795	0.204
T26-T28 Burns and corrosions confined to eye and internal organs	0.796	0.204
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.797	0.203
S66 Injury of muscle and tendon at wrist and hand level	0.797	0.203
T33-T35 Frostbite	0.797	0.203
S60.2 Contusion of other parts of wrist and hand	0.798	0.202
S64.1 Injury of median nerve at wrist and hand level	0.798	0.202
T19 Foreign body in genito-urinary tract	0.798	0.202
T86.0 Bone-marrow transplant rejection	0.798	0.202
S92 Fracture of foot, except ankle	0.798	0.202
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.798	0.202
S60.7 Multiple superficial injuries of wrist and hand	0.798	0.201
T18.8 Foreign body in other and multiple parts of alimentary tract	0.799	0.201
T18.4 Foreign body in colon	0.799	0.201
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.800	0.200
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.800	0.199
T01 Open wounds involving multiple body regions	0.801	0.199
S91 Open wound of ankle and foot	0.802	0.198
S64.0 Injury of ulnar nerve at wrist and hand level	0.802	0.198
T15 Foreign body on external eye	0.802	0.198
T83.3 Mechanical complication of intra-uterine contraceptive device	0.802	0.197
S60.0 Contusion of finger(s) without damage to nail	0.803	0.197
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.803	0.196
T02 Fractures involving multiple body regions	0.806	0.194
T00.9 Multiple superficial injuries, unspecified	0.806	0.194
S98 Traumatic amputation of ankle and foot	0.807	0.193
S64.3 Injury of digital nerve of thumb	0.808	0.191
T79-T79 Certain early complications of trauma	0.809	0.191
T18.2 Foreign body in stomach	0.809	0.191
T87.6 Other and unspecified complications of amputation stump	0.809	0.191
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.809	0.191
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.811	0.189
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.811	0.189
T88 Other complications of surgical and medical care, not elsewhere classified	0.811	0.189
S62.3 Fracture of other metacarpal bone	0.812	0.188
S69 Other and unspecified injuries of wrist and hand	0.814	0.186
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.815	0.185
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.816	0.184
S68 Traumatic amputation of wrist and hand	0.816	0.184
T05 Traumatic amputations involving multiple body regions	0.816	0.183
T04 Crushing injuries involving multiple body regions	0.816	0.183
T03 Dislocations, sprains and strains involving multiple body regions	0.816	0.183
T07 Unspecified multiple injuries	0.816	0.183
T87.4 Infection of amputation stump	0.817	0.183
T00.8 Superficial injuries involving other combinations of body regions	0.819	0.181
T06 Other injuries involving multiple body regions, not elsewhere classified	0.821	0.179
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.821	0.179
T86.4 Liver transplant failure and rejection	0.821	0.178
T80.6 Other serum reactions	0.822	0.178
T80.5 Anaphylactic shock due to serum	0.822	0.178
T80.4 Rh incompatibility reaction	0.822	0.178
T80.3 ABO incompatibility reaction	0.822	0.178
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.822	0.178
S20-S29 Injuries to the thorax	0.822	0.178
T86.3 Heart-lung transplant failure and rejection	0.822	0.178
T86.2 Heart transplant failure and rejection	0.822	0.178
S92.3 Fracture of metatarsal bone	0.823	0.177
S95 Injury of blood vessels at ankle and foot level	0.823	0.177
S94 Injury of nerves at ankle and foot level	0.823	0.177
S99 Other and unspecified injuries of ankle and foot	0.823	0.177
S62.30 Fracture of other metacarpal bone (closed)	0.823	0.177
S60.8 Other superficial injuries of wrist and hand	0.823	0.176
S64.7 Injury of multiple nerves at wrist and hand level	0.824	0.176
T17 Foreign body in respiratory tract	0.829	0.171
T66-T78 Other and unspecified effects of external causes	0.830	0.170
S96.8 Injury of other muscles and tendons at ankle and foot level	0.830	0.170
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.830	0.170
S91.2 Open wound of toe(s) with damage to nail	0.831	0.169
S62.6 Fracture of other finger	0.831	0.169
S65 Injury of blood vessels at wrist and hand level	0.831	0.168
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.833	0.167
S91.3 Open wound of other parts of foot	0.834	0.166
S60.1 Contusion of finger(s) with damage to nail	0.834	0.166
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.834	0.166
T87.2 Complications of other reattached body part	0.834	0.166
T87.1 Complications of reattached (part of) lower extremity	0.834	0.166
T87.0 Complications of reattached (part of) upper extremity	0.834	0.166
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.835	0.165
S64.9 Injury of unspecified nerve at wrist and hand level	0.835	0.165
S64.8 Injury of other nerves at wrist and hand level	0.835	0.165
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.835	0.165
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.836	0.164
T00.0 Superficial injuries involving head with neck	0.836	0.164
S67 Crushing injury of wrist and hand	0.836	0.164
S62.2 Fracture of first metacarpal bone	0.837	0.163
T86.1 Kidney transplant failure and rejection	0.837	0.162
S62.8 Fracture of other and unspecified parts of wrist and hand	0.838	0.162
S97 Crushing injury of ankle and foot	0.838	0.161
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.839	0.161
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.839	0.161
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.839	0.161
S27 Injury of other and unspecified intrathoracic organs	0.840	0.160
T87.3 Neuroma of amputation stump	0.840	0.160
S92.30 Fracture of metatarsal bone (closed)	0.841	0.159
T20-T25 Burns and corrosions of external body surface, specified by site	0.841	0.158
T87.5 Necrosis of amputation stump	0.842	0.157
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.843	0.157
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.843	0.157
T01.8 Open wounds involving other combinations of body regions	0.843	0.157
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.844	0.156
S98.1 Traumatic amputation of one toe	0.845	0.155
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.846	0.154
T29 Burns and corrosions of multiple body regions	0.848	0.152
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.848	0.152
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.848	0.152
T19.0 Foreign body in urethra	0.848	0.152
T02.8 Fractures involving other combinations of body regions	0.849	0.151
T88.9 Complication of surgical and medical care, unspecified	0.849	0.151
T15.0 Foreign body in cornea	0.849	0.151
S92.2 Fracture of other tarsal bone(s)	0.849	0.151
S68.0 Traumatic amputation of thumb (complete)(partial)	0.849	0.151
T19.2 Foreign body in vulva and vagina	0.849	0.150
S62.7 Multiple fractures of fingers	0.850	0.150
T59 Toxic effect of other gases, fumes and vapours	0.851	0.149
S92.9 Fracture of foot, unspecified	0.851	0.148
S92.5 Fracture of other toe	0.851	0.148
T26 Burn and corrosion confined to eye and adnexa	0.852	0.148
T85.2 Mechanical complication of intraocular lens	0.853	0.147
T30 Burn and corrosion, body region unspecified	0.853	0.146
T28 Burn and corrosion of other internal organs	0.853	0.146
T27 Burn and corrosion of respiratory tract	0.853	0.146
T02.4 Fractures involving multiple regions of both upper limbs	0.853	0.146
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.854	0.146
T35 Frostbite involving multiple body regions and unspecified frostbite	0.854	0.145
T34 Frostbite with tissue necrosis	0.854	0.145
T33 Superficial frostbite	0.854	0.145
S90 Superficial injury of ankle and foot	0.855	0.145
T19.9 Foreign body in genito-urinary tract, part unspecified	0.855	0.145
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.855	0.145
T19.3 Foreign body in uterus [any part]	0.855	0.145
S92.7 Multiple fractures of foot	0.855	0.145
T01.3 Open wounds involving multiple regions of lower limb(s)	0.855	0.144
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.856	0.144
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.857	0.143
T32 Corrosions classified according to extent of body surface involved	0.857	0.143
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.857	0.143
T01.9 Multiple open wounds, unspecified	0.857	0.142
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.857	0.142
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.857	0.142
T01.0 Open wounds involving head with neck	0.857	0.142
S91.7 Multiple open wounds of ankle and foot	0.858	0.142
T15.8 Foreign body in other and multiple parts of external eye	0.858	0.142
S62.1 Fracture of other carpal bone(s)	0.858	0.141
S69.7 Multiple injuries of wrist and hand	0.858	0.141
T01.2 Open wounds involving multiple regions of upper limb(s)	0.859	0.141
S92.4 Fracture of great toe	0.859	0.141
S10-S19 Injuries to the neck	0.860	0.140
T83.1 Mechanical complication of other urinary devices and implants	0.860	0.140
T63 Toxic effect of contact with venomous animals	0.860	0.140
S92.1 Fracture of talus	0.860	0.140
T02.9 Multiple fractures, unspecified	0.860	0.139
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.860	0.139
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.860	0.139
T02.3 Fractures involving multiple regions of one lower limb	0.860	0.139
T02.1 Fractures involving thorax with lower back and pelvis	0.860	0.139
T02.0 Fractures involving head with neck	0.860	0.139
T88.7 Unspecified adverse effect of drug or medicament	0.860	0.140
S98.4 Traumatic amputation of foot, level unspecified	0.861	0.139
S98.3 Traumatic amputation of other parts of foot	0.861	0.139
S98.2 Traumatic amputation of two or more toes	0.861	0.139
S98.0 Traumatic amputation of foot at ankle level	0.861	0.139
T54 Toxic effect of corrosive substances	0.862	0.138
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.862	0.138
T15.1 Foreign body in conjunctival sac	0.862	0.137
T88.3 Malignant hyperthermia due to anaesthesis	0.862	0.137
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.863	0.137
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.863	0.137
S62.4 Multiple fractures of metacarpal bones	0.863	0.137
T51 Toxic effect of alcohol	0.863	0.137
S27.1 Traumatic haemothorax	0.863	0.137
T02.5 Fractures involving multiple regions of both lower limbs	0.863	0.137
T25 Burn and corrosion of ankle and foot	0.863	0.137
S62.0 Fracture of navicular [scaphoid] bone of hand	0.864	0.136
T70 Effects of air pressure and water pressure	0.864	0.136
T31 Burns classified according to extent of body surface involved	0.864	0.136
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.864	0.136
T60 Toxic effect of pesticides	0.864	0.135
T57 Toxic effect of other inorganic substances	0.864	0.135
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.864	0.135
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.864	0.135
T88.1 Other complications following immunisation, not elsewhere classified	0.864	0.135
T88.0 Infection following immunisation	0.864	0.135
S27.2 Traumatic heamopneumothorax	0.865	0.135
T68 Hypothermia	0.865	0.135
S62.61 Fracture of other finger (open)	0.866	0.134
T02.2 Fractures involving multiple regions of one upper limb	0.867	0.133
T61 Toxic effect of noxious substances eaten as seafood	0.867	0.133
T19.1 Foreign body in bladder	0.867	0.133
T52 Toxic effect of organic solvents	0.867	0.133
T17.2 Foreign body in pharynx	0.867	0.133
T82.4 Mechanical complication of vascular dialysis catheter	0.867	0.132
T56 Toxic effect of metals	0.867	0.132
T55 Toxic effect of soaps and detergents	0.868	0.132
S69.8 Other specified injuries of wrist and hand	0.868	0.132
T15.9 Foreign body on external eye, unspecified	0.868	0.132
S91.1 Open wound of toe(s) without damage to nail	0.868	0.132
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.868	0.132
S68.8 Traumatic amputation of other parts of wrist and hand	0.868	0.132
S68.4 Traumatic amputation of hand at wrist level	0.868	0.132
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.868	0.132
T03.9 Multiple dislocations, sprains and strains, unspecified	0.868	0.132
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.868	0.132
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.868	0.132
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.868	0.132
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.868	0.132
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.868	0.132
T03.0 Dislocations, sprains and strains involving head with neck	0.868	0.132
T04.9 Multiple crushing injuries, unspecified	0.868	0.132
T04.8 Crushing injuries involving other combinations of body regions	0.868	0.132
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.868	0.132
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.868	0.132
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.868	0.132
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.868	0.132
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.868	0.132
T04.0 Crushing injuries involving head with neck	0.868	0.132
T05.9 Multiple traumatic amputations, unspecified	0.868	0.132
T05.8 Traumatic amputations involving other combinations of body regions	0.868	0.132
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.868	0.132
T05.5 Traumatic amputation of both legs [any level]	0.868	0.132
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.868	0.132
T05.3 Traumatic amputation of both feet	0.868	0.132
T05.2 Traumatic amputation of both arms [any level]	0.868	0.132
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.868	0.132
T05.0 Traumatic amputation of both hands	0.868	0.132
T62 Toxic effect of other noxious substances eaten as food	0.868	0.132
T66 Unspecified effects of radiation	0.869	0.131
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.869	0.131
S62.60 Fracture of other finger (closed)	0.870	0.130
S50-S59 Injuries to the elbow and forearm	0.870	0.130
T88.5 Other complications of anaesthesia	0.870	0.129
S62.20 Fracture of first metacarpal bone (closed)	0.870	0.129
S26 Injury of heart	0.871	0.129
T17.3 Foreign body in larynx	0.871	0.128
T06.8 Other specified injuries involving multiple body regions	0.871	0.128
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.871	0.128
T06.3 Injuries of blood vessels involving multiple body regions	0.871	0.128
T06.2 Injuries of nerves involving multiple body regions	0.871	0.128
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.871	0.128
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.871	0.128
S69.9 Unspecified injury of wrist and hand	0.872	0.128
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.872	0.128
S25 Injury of blood vessels of thorax	0.872	0.128
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.872	0.128
S27.3 Other injuries of lung	0.872	0.128
S99.9 Unspecified injury of ankle and foot	0.873	0.127
T58 Toxic effect of carbon monoxide	0.873	0.127
S92.31 Fracture of metatarsal bone (open)	0.873	0.127
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.873	0.127
S94.9 Injury of unspecified nerve at ankle and foot level	0.873	0.127
S94.8 Injury of other nerves at ankle and foot level	0.873	0.127
S94.7 Injury of multiple nerves at ankle and foot level	0.873	0.127
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.873	0.127
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.873	0.127
S94.1 Injury of medial plantar nerve	0.873	0.127
S94.0 Injury of lateral plantar nerve	0.873	0.127
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.873	0.127
S95.8 Injury of other blood vessels at ankle and foot level	0.873	0.127
S95.7 Injury of multiple blood vessels at ankle and foot level	0.873	0.127
S95.2 Injury of dorsal vein of foot	0.873	0.127
S95.1 Injury of plantar artery of foot	0.873	0.127
S95.0 Injury of dorsal artery of foot	0.873	0.127
S99.7 Multiple injuries of ankle and foot	0.873	0.127
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.874	0.126
T79 Certain early complications of trauma, not elsewhere classified	0.874	0.126
S99.8 Other specified injuries of ankle and foot	0.874	0.126
T80.2 Infections following infusion, transfusion and therapeutic injection	0.874	0.125
T59.9 Gases, fumes and vapours, unspecified	0.875	0.125
S20 Superficial injury of thorax	0.875	0.125
S65.0 Injury of ulnar artery at wrist and hand level	0.876	0.124
T06.4 Injuries of muscles and tendons involving multiple body regions	0.876	0.124
S65.4 Injury of blood vessel(s) of thumb	0.876	0.124
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.876	0.124
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.876	0.123
S92.0 Fracture of calcaneus	0.877	0.123
T17.4 Foreign body in trachea	0.877	0.123
T17.1 Foreign body in nostril	0.877	0.123
T17.0 Foreign body in nasal sinus	0.877	0.123
T74 Maltreatment syndromes	0.878	0.122
T73 Effects of other deprivation	0.878	0.122
T69 Other effects of reduced temperature	0.878	0.122
T67 Effects of heat and light	0.878	0.122
S64.4 Injury of digital nerve of other finger	0.878	0.122
S93.0 Dislocation of ankle joint	0.878	0.122
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.878	0.122
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.879	0.121
S65.8 Injury of other blood vessels at wrist and hand level	0.879	0.121
S65.7 Injury of multiple blood vessels at wrist and hand level	0.879	0.121
S65.3 Injury of deep palmar arch	0.879	0.121
S65.2 Injury of superficial palmar arch	0.879	0.121
T02.80 Fractures involving other combinations of body regions (closed)	0.879	0.120
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.880	0.120
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.880	0.120
S93.3 Dislocation of other and unspecified parts of foot	0.880	0.120
T65 Toxic effect of other and unspecified substances	0.880	0.119
T82.0 Mechanical complication of heart valve prosthesis	0.881	0.119
S24 Injury of nerves and spinal cord at thorax level	0.881	0.119
T17.5 Foreign body in bronchus	0.882	0.118
S92.50 Fracture of other toe (closed)	0.883	0.117
S62.21 Fracture of first metacarpal bone (open)	0.883	0.117
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.883	0.117
S62.31 Fracture of other metacarpal bone (open)	0.883	0.116
T25.2 Burn of second degree of ankle and foot	0.884	0.116
S65.5 Injury of blood vessel(s) of other finger	0.884	0.116
S97.0 Crushing injury of ankle	0.884	0.116
S27.8 Injury of other specified intrathoracic organs	0.884	0.115
S93.4 Sprain and strain of ankle	0.884	0.115
S93.5 Sprain and strain of toe(s)	0.884	0.115
S97.1 Crushing injury of toe(s)	0.884	0.115
T17.8 Foreign body in other and multiple parts of respiratory tract	0.885	0.115
S27.9 Injury of unspecified intrathoracic organ	0.885	0.115
S27.7 Multiple injuries of intrathoracic organs	0.885	0.115
S27.6 Injury of pleura	0.885	0.115
S27.5 Injury of thoracic trachea	0.885	0.115

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations