TreeWAS – Variant ID: rs4739066

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R06.0 Dyspnoea	0.000	0.963	0.037
M20-M25 Other joint disorders	0.037	0.963	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.037	0.963	0.000
M21 Other acquired deformities of limbs	0.036	0.964	0.000
M21.1 Varus deformity, not elsewhere classified	0.036	0.964	0.000
M25 Other joint disorders, not elsewhere classified	0.034	0.966	0.000
M67.8 Other specified disorders of synovium and tendon	0.033	0.967	0.000
M67 Other disorders of synovium and tendon	0.032	0.968	0.000
M65-M68 Disorders of synovium and tendon	0.032	0.968	0.000
M35 Other systemic involvement of connective tissue	0.032	0.968	0.000
M23 Internal derangement of knee	0.032	0.968	0.000
M23.8 Other internal derangements of knee	0.031	0.969	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.031	0.969	0.000
M24 Other specific joint derangements	0.031	0.969	0.000
M21.2 Flexion deformity	0.031	0.969	0.000
M25.5 Pain in joint	0.031	0.969	0.000
M25.56 Pain in joint (Lower leg)	0.030	0.970	0.000
M31 Other necrotising vasculopathies	0.029	0.971	0.000
M21.7 Unequal limb length (acquired)	0.029	0.971	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.029	0.971	0.000
M65 Synovitis and tenosynovitis	0.029	0.971	0.000
M33 Dermatopolymyositis	0.028	0.972	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.028	0.972	0.000
M23.4 Loose body in knee	0.027	0.973	0.000
M25.57 Pain in joint (Ankle and foot)	0.027	0.973	0.000
M60-M63 Disorders of muscles	0.027	0.973	0.000
M86-M90 Other osteopathies	0.027	0.973	0.000
M35.0 Sicca syndrome [Sjogren]	0.027	0.973	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.026	0.973	0.000
M32 Systemic lupus erythematosus	0.026	0.973	0.000
M30 Polyarteritis nodosa and related conditions	0.026	0.973	0.000
M21.27 Flexion deformity (Ankle and foot)	0.026	0.973	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.026	0.974	0.000
M40-M43 Deforming dorsopathies	0.026	0.974	0.000
M21.9 Acquired deformity of limb, unspecified	0.026	0.974	0.000
M21.8 Other specified acquired deformities of limbs	0.026	0.974	0.000
M21.6 Other acquired deformities of ankle and foot	0.026	0.974	0.000
M21.4 Flat foot [pes planus] (acquired)	0.026	0.974	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.026	0.974	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.026	0.974	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.026	0.974	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.026	0.974	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.026	0.974	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.026	0.974	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.026	0.974	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.026	0.974	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.026	0.974	0.000
M35.8 Other specified systemic involvement of connective tissue	0.026	0.974	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.026	0.974	0.000
M34 Systemic sclerosis	0.026	0.974	0.000
M23.0 Cystic meniscus	0.026	0.974	0.000
M24.1 Other articular cartilage disorders	0.026	0.974	0.000
M23.5 Chronic instability of knee	0.026	0.974	0.000
M25.8 Other specified joint disorders	0.026	0.974	0.000
M25.51 Pain in joint (Shoulder region)	0.025	0.975	0.000
M24.5 Contracture of joint	0.025	0.975	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.025	0.975	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.024	0.975	0.000
M45-M49 Spondylopathies	0.025	0.975	0.000
M25.9 Joint disorder, unspecified	0.024	0.975	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.024	0.976	0.000
M25.2 Flail joint	0.024	0.976	0.000
M25.1 Fistula of joint	0.024	0.976	0.000
M25.0 Haemarthrosis	0.024	0.976	0.000
M35.1 Other overlap syndromes	0.024	0.976	0.000
M31.0 Hypersensitivity angiitis	0.024	0.976	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.024	0.976	0.000
M23.9 Internal derangement of knee, unspecified	0.024	0.976	0.000
M35.3 Polymyalgia rheumatica	0.024	0.976	0.000
M24.6 Ankylosis of joint	0.024	0.976	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.024	0.976	0.000
M25.7 Osteophyte	0.024	0.976	0.000
M25.4 Effusion of joint	0.024	0.976	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.024	0.976	0.000
M65.3 Trigger finger	0.024	0.976	0.000
M67.4 Ganglion	0.024	0.976	0.000
M60 Myositis	0.024	0.976	0.000
M25.50 Pain in joint (Multiple sites)	0.024	0.976	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.023	0.977	0.000
M67.3 Transient synovitis	0.023	0.977	0.000
M67.0 Short Achilles tendon (acquired)	0.023	0.977	0.000
D12.6 Colon, unspecified	0.000	0.977	0.023
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.023	0.977	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.023	0.977	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.023	0.977	0.000
M35.5 Multifocal fibrosclerosis	0.023	0.977	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.023	0.977	0.000
M35.2 Behcet's disease	0.023	0.977	0.000
M23.1 Discoid meniscus (congenital)	0.023	0.977	0.000
M05-M14 Inflammatory polyarthropathies	0.023	0.977	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.023	0.977	0.000
M43 Other deforming dorsopathies	0.023	0.977	0.000
M00-M03 Infectious arthropathies	0.023	0.977	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.023	0.977	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.023	0.977	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.023	0.977	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.023	0.977	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.023	0.977	0.000
M35.7 Hypermobility syndrome	0.023	0.977	0.000
M25.54 Pain in joint (Hand)	0.023	0.977	0.000
M21.26 Flexion deformity (Lower leg)	0.022	0.977	0.000
M24.9 Joint derangement, unspecified	0.022	0.977	0.000
M24.7 Protrusio acetabuli	0.022	0.977	0.000
M21.24 Flexion deformity (Hand)	0.022	0.978	0.000
M23.49 Loose body in knee-Unspec lig/men	0.022	0.978	0.000
M21.29 Flexion deformity (Site unspecified)	0.022	0.978	0.000
M21.28 Flexion deformity (Other)	0.022	0.978	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.022	0.978	0.000
M21.23 Flexion deformity (Forearm)	0.022	0.978	0.000
M21.22 Flexion deformity (Upper arm)	0.022	0.978	0.000
M21.21 Flexion deformity (Shoulder region)	0.022	0.978	0.000
M21.20 Flexion deformity (Multiple sites)	0.022	0.978	0.000
M33.2 Polymyositis	0.022	0.978	0.000
M65.8 Other synovitis and tenosynovitis	0.022	0.978	0.000
M25.3 Other instability of joint	0.022	0.978	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.022	0.978	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.022	0.978	0.000
M23.43 Loose body in knee-Med lig/oth men	0.022	0.978	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.022	0.978	0.000
M25.58 Pain in joint (Other)	0.022	0.978	0.000
M88 Paget's disease of bone [osteitis deformans]	0.022	0.978	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.022	0.978	0.000
M21.0 Valgus deformity, not elsewhere classified	0.022	0.978	0.000
M66 Spontaneous rupture of synovium and tendon	0.022	0.978	0.000
M21.3 Wrist or foot drop (acquired)	0.021	0.978	0.000
M31.3 Wegener's granulomatosis	0.021	0.978	0.000
M24.2 Disorder of ligament	0.021	0.978	0.000
M67.1 Other contracture of tendon (sheath)	0.021	0.979	0.000
M31.9 Necrotising vasculopathy, unspecified	0.021	0.979	0.000
M31.8 Other specified necrotising vasculopathies	0.021	0.979	0.000
M31.7 Microscopic polyangiitis	0.021	0.979	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.021	0.979	0.000
M31.2 Lethal midline granuloma	0.021	0.979	0.000
M31.1 Thrombotic microangiopathy	0.021	0.979	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.021	0.979	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.021	0.979	0.000
M21.78 Unequal limb length (acquired)-Other	0.021	0.979	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.021	0.979	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.021	0.979	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.021	0.979	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.021	0.979	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.021	0.979	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.021	0.979	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.021	0.979	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.021	0.979	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.021	0.979	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.021	0.979	0.000
M90 Osteopathies in diseases classified elsewhere	0.021	0.979	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.021	0.979	0.000
M40 Kyphosis and lordosis	0.021	0.979	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.021	0.979	0.000
M89 Other disorders of bone	0.021	0.979	0.000
M31.6 Other giant cell arteritis	0.021	0.979	0.000
M65.34 Trigger finger-Hand	0.021	0.979	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.021	0.979	0.000
M65.2 Calcific tendinitis	0.021	0.979	0.000
M65.1 Other infective (teno)synovitis	0.021	0.979	0.000
M65.0 Abscess of tendon sheath	0.021	0.979	0.000
M25.77 Osteophyte (Ankle and foot)	0.021	0.979	0.000
M25.88 Other specified joint disorders (Other)	0.020	0.979	0.000
M33.9 Dermatopolymyositis, unspecified	0.020	0.979	0.000
M33.1 Other dermatomyositis	0.020	0.979	0.000
M33.0 Juvenile dermatomyositis	0.020	0.979	0.000
M25.59 Pain in joint (Site unspecified)	0.020	0.980	0.000
M62 Other disorders of muscle	0.020	0.980	0.000
M25.74 Osteophyte (Hand)	0.020	0.980	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.020	0.980	0.000
M48 Other spondylopathies	0.020	0.980	0.000
M60.0 Infective myositis	0.020	0.980	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.020	0.980	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.020	0.980	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.020	0.980	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.020	0.980	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.020	0.980	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.020	0.980	0.000
M70-M79 Other soft tissue disorders	0.020	0.980	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.020	0.980	0.000
M25.94 Joint disorder, unspecified (Hand)	0.020	0.980	0.000
M91-M94 Chondropathies	0.020	0.980	0.000
M23.47 Loose body in knee-Capsular lig	0.020	0.980	0.000
M23.46 Loose body in knee-O/unsp lat men	0.020	0.980	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.020	0.980	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.020	0.980	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.020	0.980	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.020	0.980	0.000
M23.40 Loose body in knee-Mult sites	0.020	0.980	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.020	0.980	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.020	0.980	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.019	0.980	0.000
M61 Calcification and ossification of muscle	0.019	0.980	0.000
M24.56 Contracture of joint (Lower leg)	0.019	0.980	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.019	0.980	0.000
M46 Other inflammatory spondylopathies	0.019	0.980	0.000
M87 Osteonecrosis	0.019	0.981	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.019	0.981	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.019	0.981	0.000
M30.2 Juvenile polyarteritis	0.019	0.981	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.019	0.981	0.000
M30.0 Polyarteritis nodosa	0.019	0.981	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.019	0.981	0.000
M32.8 Other forms of systemic lupus erythematosus	0.019	0.981	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.019	0.981	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.019	0.981	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.019	0.981	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.019	0.981	0.000
M36.3 Arthropathy in other blood disorders	0.019	0.981	0.000
M36.2 Haemophilic arthropathy	0.019	0.981	0.000
M36.1 Arthropathy in neoplastic disease	0.019	0.981	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.019	0.981	0.000
M25.46 Effusion of joint (Lower leg)	0.019	0.981	0.000
M24.54 Contracture of joint (Hand)	0.019	0.981	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.019	0.981	0.000
M60.9 Myositis, unspecified	0.019	0.981	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.019	0.981	0.000
M22 Disorders of patella	0.019	0.981	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.019	0.981	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.019	0.981	0.000
M42 Spinal osteochondrosis	0.019	0.981	0.000
M24.0 Loose body in joint	0.019	0.981	0.000
M43.1 Spondylolisthesis	0.019	0.981	0.000
M34.8 Other forms of systemic sclerosis	0.019	0.981	0.000
R06 Abnormalities of breathing	0.000	0.981	0.019
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.019	0.981	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.019	0.981	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.019	0.981	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.019	0.981	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.019	0.981	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.019	0.981	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.019	0.981	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.019	0.981	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.019	0.981	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.019	0.981	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.019	0.981	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.019	0.981	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.019	0.981	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.019	0.981	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.019	0.981	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.019	0.981	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.019	0.981	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.019	0.981	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.019	0.981	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.019	0.981	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.019	0.981	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.019	0.981	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.019	0.981	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.019	0.981	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.019	0.981	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.019	0.981	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.019	0.981	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.019	0.981	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.019	0.981	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.019	0.981	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.019	0.981	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.019	0.981	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.019	0.981	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.019	0.981	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.019	0.981	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.019	0.981	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.019	0.981	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.019	0.981	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.019	0.981	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.019	0.981	0.000
M25.52 Pain in joint (Upper arm)	0.019	0.981	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.019	0.981	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.019	0.981	0.000
M34.1 CR(E)ST syndrome	0.019	0.981	0.000
M34.0 Progressive systemic sclerosis	0.019	0.981	0.000
M86 Osteomyelitis	0.019	0.981	0.000
M43.0 Spondylolysis	0.019	0.981	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.019	0.981	0.000
M23.07 Cystic meniscus-Capsular lig	0.018	0.981	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.018	0.981	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.018	0.981	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.018	0.981	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.018	0.981	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.018	0.981	0.000
M23.00 Cystic meniscus (Multiple sites)	0.018	0.981	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.019	0.981	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.019	0.981	0.000
M24.18 Other articular cartilage disorders (Other)	0.019	0.981	0.000
M24.14 Other articular cartilage disorders (Hand)	0.019	0.981	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.019	0.981	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.019	0.981	0.000
M25.42 Effusion of joint (Upper arm)	0.019	0.981	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.018	0.981	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.018	0.981	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.018	0.981	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.018	0.981	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.018	0.981	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.018	0.981	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.018	0.981	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.018	0.981	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.018	0.981	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.019	0.981	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.018	0.981	0.000
M25.83 Other specified joint disorders (Forearm)	0.018	0.981	0.000
M25.82 Other specified joint disorders (Upper arm)	0.018	0.981	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.018	0.981	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.018	0.981	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.018	0.981	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.018	0.981	0.000
M25.53 Pain in joint (Forearm)	0.018	0.982	0.000
M88.9 Paget's disease of bone, unspecified	0.018	0.982	0.000
M06 Other rheumatoid arthritis	0.018	0.982	0.000
M34.9 Systemic sclerosis, unspecified	0.018	0.982	0.000
M13 Other arthritis	0.018	0.982	0.000
M24.59 Contracture of joint (Site unspecified)	0.018	0.982	0.000
M24.58 Contracture of joint (Other)	0.018	0.982	0.000
M24.57 Contracture of joint (Ankle and foot)	0.018	0.982	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.018	0.982	0.000
M24.53 Contracture of joint (Forearm)	0.018	0.982	0.000
M24.52 Contracture of joint (Upper arm)	0.018	0.982	0.000
M24.51 Contracture of joint (Shoulder region)	0.018	0.982	0.000
M24.50 Contracture of joint (Multiple sites)	0.018	0.982	0.000
M25.84 Other specified joint disorders (Hand)	0.018	0.982	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.018	0.982	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.018	0.982	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.018	0.982	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.018	0.982	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.018	0.982	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.018	0.982	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.018	0.982	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.018	0.982	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.018	0.982	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.018	0.982	0.000
M47 Spondylosis	0.018	0.982	0.000
M50-M54 Other dorsopathies	0.018	0.982	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.018	0.982	0.000
M25.98 Joint disorder, unspecified (Other)	0.018	0.982	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.018	0.982	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.018	0.982	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.018	0.982	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.018	0.982	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.018	0.982	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.018	0.982	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.018	0.982	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.018	0.982	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.018	0.982	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.018	0.982	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.018	0.982	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.018	0.982	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.018	0.982	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.018	0.982	0.000
M25.09 Haemarthrosis (Site unspecified)	0.018	0.982	0.000
M25.08 Haemarthrosis (Other)	0.018	0.982	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.018	0.982	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.018	0.982	0.000
M25.04 Haemarthrosis (Hand)	0.018	0.982	0.000
M25.03 Haemarthrosis (Forearm)	0.018	0.982	0.000
M25.02 Haemarthrosis (Upper arm)	0.018	0.982	0.000
M25.01 Haemarthrosis (Shoulder region)	0.018	0.982	0.000
M25.00 Haemarthrosis (Multiple sites)	0.018	0.982	0.000
M25.19 Fistula of joint (Site unspecified)	0.018	0.982	0.000
M25.18 Fistula of joint (Other)	0.018	0.982	0.000
M25.17 Fistula of joint (Ankle and foot)	0.018	0.982	0.000
M25.16 Fistula of joint (Lower leg)	0.018	0.982	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.018	0.982	0.000
M25.14 Fistula of joint (Hand)	0.018	0.982	0.000
M25.13 Fistula of joint (Forearm)	0.018	0.982	0.000
M25.12 Fistula of joint (Upper arm)	0.018	0.982	0.000
M25.11 Fistula of joint (Shoulder region)	0.018	0.982	0.000
M25.10 Fistula of joint (Multiple sites)	0.018	0.982	0.000
M25.29 Flail joint (Site unspecified)	0.018	0.982	0.000
M25.28 Flail joint (Other)	0.018	0.982	0.000
M25.27 Flail joint (Ankle and foot)	0.018	0.982	0.000
M25.26 Flail joint (Lower leg)	0.018	0.982	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.018	0.982	0.000
M25.24 Flail joint (Hand)	0.018	0.982	0.000
M25.23 Flail joint (Forearm)	0.018	0.982	0.000
M25.22 Flail joint (Upper arm)	0.018	0.982	0.000
M25.21 Flail joint (Shoulder region)	0.018	0.982	0.000
M25.20 Flail joint (Multiple sites)	0.018	0.982	0.000
M25.78 Osteophyte (Other)	0.018	0.982	0.000
M25.06 Haemarthrosis (Lower leg)	0.018	0.982	0.000
M80-M85 Disorders of bone density and structure	0.018	0.982	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.017	0.982	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.017	0.982	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.017	0.982	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.017	0.982	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.017	0.982	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.017	0.982	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.017	0.982	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.017	0.982	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.017	0.982	0.000
M24.68 Ankylosis of joint (Other)	0.017	0.982	0.000
M24.66 Ankylosis of joint (Lower leg)	0.017	0.982	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.017	0.982	0.000
M24.64 Ankylosis of joint (Hand)	0.017	0.982	0.000
M24.63 Ankylosis of joint (Forearm)	0.017	0.982	0.000
M24.62 Ankylosis of joint (Upper arm)	0.017	0.982	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.017	0.982	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.017	0.982	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.017	0.982	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.017	0.982	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.017	0.982	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.017	0.982	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.017	0.982	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.017	0.982	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.017	0.982	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.017	0.982	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.017	0.982	0.000
M67.43 Ganglion, wrist	0.017	0.982	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.017	0.982	0.000
M25.79 Osteophyte (Site unspecified)	0.017	0.982	0.000
M25.73 Osteophyte (Forearm)	0.017	0.982	0.000
M25.70 Osteophyte (Multiple sites)	0.017	0.982	0.000
M49 Spondylopathies in diseases classified elsewhere	0.017	0.982	0.000
M25.49 Effusion of joint (Site unspecified)	0.017	0.982	0.000
M25.48 Effusion of joint (Other)	0.017	0.982	0.000
M25.44 Effusion of joint (Hand)	0.017	0.982	0.000
M25.43 Effusion of joint (Forearm)	0.017	0.982	0.000
M25.41 Effusion of joint (Shoulder region)	0.017	0.982	0.000
M25.40 Effusion of joint (Multiple sites)	0.017	0.982	0.000
M65.39 Trigger finger-Site unspec	0.017	0.983	0.000
M65.38 Trigger finger-Other	0.017	0.983	0.000
M65.37 Trigger finger-Ankle/foot	0.017	0.983	0.000
M65.36 Trigger finger-Lower leg	0.017	0.983	0.000
M65.35 Trigger finger-Pelvic/thigh	0.017	0.983	0.000
M65.33 Trigger finger-Forearm	0.017	0.983	0.000
M65.32 Trigger finger-Upper arm	0.017	0.983	0.000
M65.31 Trigger finger-Shldr region	0.017	0.983	0.000
M65.30 Trigger finger-Mult sites	0.017	0.983	0.000
M54 Dorsalgia	0.017	0.983	0.000
M40.2 Other and unspecified kyphosis	0.017	0.983	0.000
M67.49 Ganglion, multiple sites	0.017	0.983	0.000
M67.47 Ganglion, ankle and foot	0.017	0.983	0.000
M67.45 Ganglion, hip	0.017	0.983	0.000
M60.8 Other myositis	0.017	0.983	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.017	0.983	0.000
M60.1 Interstitial myositis	0.017	0.983	0.000
M11 Other crystal arthropathies	0.017	0.983	0.000
M90.7 Fracture of bone in neoplastic disease	0.017	0.983	0.000
M47.9 Spondylosis, unspecified	0.017	0.983	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.017	0.983	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.017	0.983	0.000
M06.9 Rheumatoid arthritis, unspecified	0.017	0.983	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.017	0.983	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.017	0.983	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.017	0.983	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.017	0.983	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.017	0.983	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.017	0.983	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.017	0.983	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.017	0.983	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.017	0.983	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.017	0.983	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.017	0.983	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.017	0.983	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.017	0.983	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.017	0.983	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.017	0.983	0.000
M12 Other specific arthropathies	0.017	0.983	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.017	0.983	0.000
M08 Juvenile arthritis	0.017	0.983	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.017	0.983	0.000
M00 Pyogenic arthritis	0.017	0.983	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.017	0.983	0.000
M43.9 Deforming dorsopathy, unspecified	0.017	0.983	0.000
M43.8 Other specified deforming dorsopathies	0.017	0.983	0.000
M43.6 Torticollis	0.017	0.983	0.000
M43.5 Other recurrent vertebral subluxation	0.017	0.983	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.017	0.983	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.017	0.983	0.000
M43.2 Other fusion of spine	0.017	0.983	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.016	0.983	0.000
M02 Reactive arthropathies	0.016	0.983	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.016	0.983	0.000
M10 Gout	0.017	0.983	0.000
M54.56 Low back pain (Lumbar region)	0.017	0.983	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.016	0.983	0.000
M41 Scoliosis	0.016	0.983	0.000
M48.06 Spinal stenosis (Lumbar region)	0.017	0.983	0.000
M13.0 Polyarthritis, unspecified	0.016	0.984	0.000
M24.79 Protrusio acetabuli-Site unspec	0.016	0.984	0.000
M24.78 Protrusio acetabuli-Other	0.016	0.984	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.016	0.984	0.000
M24.76 Protrusio acetabuli-Lower leg	0.016	0.984	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.016	0.984	0.000
M24.74 Protrusio acetabuli-Hand	0.016	0.984	0.000
M24.73 Protrusio acetabuli-Forearm	0.016	0.984	0.000
M24.72 Protrusio acetabuli-Upper arm	0.016	0.984	0.000
M24.71 Protrusio acetabuli-Shldr region	0.016	0.984	0.000
M24.70 Protrusio acetabuli-Mult sites	0.016	0.984	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.016	0.984	0.000
M24.98 Joint derangement, unspecified (Other)	0.016	0.984	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.016	0.984	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.016	0.984	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.016	0.984	0.000
M24.94 Joint derangement, unspecified (Hand)	0.016	0.984	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.016	0.984	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.016	0.984	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.016	0.984	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.016	0.984	0.000
M76 Enthesopathies of lower limb, excluding foot	0.016	0.984	0.000
M24.26 Disorder of ligament (Lower leg)	0.016	0.984	0.000
M14 Arthropathies in other diseases classified elsewhere	0.016	0.984	0.000
R06.8 Other and unspecified abnormalities of breathing	0.000	0.984	0.016
M89.8 Other specified disorders of bone	0.016	0.984	0.000
M25.39 Other instability of joint (Site unspecified)	0.016	0.984	0.000
M25.38 Other instability of joint (Other)	0.016	0.984	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations