TreeWAS – Variant ID: rs475937

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.097	0.903
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.104	0.896
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.107	0.893
T50.9 Other and unspecified drugs, medicaments and biological substances	0.115	0.885
T43.2 Other and unspecified antidepressants	0.128	0.872
T46 Poisoning by agents primarily affecting the cardiovascular system	0.167	0.833
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.218	0.782
T46.4 Angiotensin-converting-enzyme inhibitors	0.219	0.781
T43.0 Tricyclic and tetracyclic antidepressants	0.229	0.771
T43.5 Other and unspecified antipsychotics and neuroleptics	0.239	0.761
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.244	0.755
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.248	0.752
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.263	0.737
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.286	0.714
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.289	0.711
T50.6 Antidotes and chelating agents, not elsewhere classified	0.297	0.703
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.308	0.692
T43.4 Butyrophenone and thioxanthene neuroleptics	0.310	0.689
T47.1 Other antacids and anti-gastric-secretion drugs	0.314	0.686
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.328	0.672
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.329	0.671
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.330	0.670
T50.1 Loop [high-ceiling] diuretics	0.331	0.669
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.340	0.660
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.343	0.657
T43.6 Psychostimulants with abuse potential	0.348	0.651
T43.8 Other psychotropic drugs, not elsewhere classified	0.357	0.643
T50.7 Analeptics and opioid receptor antagonists	0.359	0.640
T50.5 Appetite depressants	0.359	0.640
T50.3 Electrolytic, caloric and water-balance agents	0.359	0.640
T50.0 Mineralocorticoids and their antagonists	0.359	0.640
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.361	0.639
T42.3 Barbiturates	0.364	0.636
T50.4 Drugs affecting uric acid metabolism	0.366	0.634
T46.3 Coronary vasodilators, not elsewhere classified	0.369	0.631
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.379	0.621
T41 Poisoning by anaesthetics and therapeutic gases	0.381	0.619
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.384	0.616
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.388	0.612
T50.8 Diagnostic agents	0.394	0.606
T46.8 Antivaricose drugs, including sclerosing agents	0.403	0.597
T46.7 Peripheral vasodilators	0.403	0.597
T36 Poisoning by systemic antibiotics	0.405	0.594
T43.3 Phenothiazine antipsychotics and neuroleptics	0.406	0.594
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.413	0.587
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.414	0.586
T43.9 Psychotropic drug, unspecified	0.416	0.584
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.420	0.579
T42.0 Hydantoin derivatives	0.423	0.577
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.423	0.577
T46.5 Other antihypertensive drugs, not elsewhere classified	0.424	0.576
T45.2 Vitamins, not elsewhere classified	0.427	0.573
T46.1 Calcium-channel blockers	0.428	0.572
T40.2 Other opioids	0.429	0.571
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.431	0.569
T40.5 Cocaine	0.433	0.567
T45.1 Antineoplastic and immunosuppressive drugs	0.434	0.566
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.434	0.566
T42.5 Mixed antiepileptics, not elsewhere classified	0.439	0.561
T42.2 Succinimides and oxazolidinediones	0.439	0.561
T45.0 Antiallergic and antiemetic drugs	0.439	0.560
T38.0 Glucocorticoids and synthetic analogues	0.446	0.554
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.447	0.553
T40.1 Heroin	0.454	0.546
T42.4 Benzodiazepines	0.456	0.544
T47.0 Histamine H(2)-receptor antagonists	0.457	0.543
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.458	0.542
T47.8 Other agents primarily affecting the gastro-intestinal system	0.458	0.542
T47.7 Emetics	0.458	0.542
T47.5 Digestants	0.458	0.542
T47.3 Saline and osmotic laxatives	0.458	0.542
T39.4 Antirheumatics, not elsewhere classified	0.461	0.539
T39.2 Pyrazolone derivatives	0.461	0.539
T45.9 Primarily systemic and haematological agent, unspecified	0.471	0.529
T45.8 Other primarily systemic and haematological agents	0.471	0.529
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.471	0.529
T45.6 Fibrinolysis-affecting drugs	0.471	0.529
T45.4 Iron and its compounds	0.471	0.529
T45.3 Enzymes, not elsewhere classified	0.471	0.529
T47.4 Other laxatives	0.474	0.526
T38.5 Other oestrogens and progestogens	0.479	0.521
T45.5 Anticoagulants	0.479	0.520
T38.8 Other and unspecified hormones and their synthetic substitutes	0.482	0.518
T47.6 Antidiarrhoeal drugs	0.484	0.516
T38.1 Thyroid hormones and substitutes	0.487	0.513
T38.9 Other and unspecified hormone antagonists	0.488	0.512
T38.7 Androgens and anabolic congeners	0.488	0.512
T38.4 Oral contraceptives	0.488	0.512
T38.2 Antithyroid drugs	0.488	0.512
T48.5 Anti-common-cold drugs	0.490	0.510
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.493	0.507
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.504	0.496
T40.8 Lysergide [LSD]	0.504	0.496
T40.7 Cannabis (derivatives)	0.504	0.496
T40.0 Opium	0.504	0.496
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.504	0.496
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.507	0.493
T39.0 Salicylates	0.508	0.492
T42.1 Iminostilbenes	0.509	0.491
T49.9 Topical agent, unspecified	0.518	0.482
T49.8 Other topical agents	0.518	0.482
T49.7 Dental drugs, topically applied	0.518	0.482
T49.6 Otorhinolaryngological drugs and preparations	0.518	0.482
T49.5 Ophthalmological drugs and preparations	0.518	0.482
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.518	0.482
T49.3 Emollients, demulcents and protectants	0.518	0.482
T49.2 Local astringents and local detergents	0.518	0.482
T49.1 Antipruritics	0.518	0.482
T47.2 Stimulant laxatives	0.518	0.482
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.520	0.480
T48.4 Expectorants	0.520	0.480
T48.3 Antitussives	0.520	0.480
T48.2 Other and unspecified agents primarily acting on muscles	0.520	0.480
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.520	0.480
T48.0 Oxytocic drugs	0.520	0.480
T40.3 Methadone	0.522	0.478
T48.6 Antiasthmatics, not elsewhere classified	0.529	0.471
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.529	0.471
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.529	0.471
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.529	0.471
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.529	0.471
T44.1 Other parasympathomimetics [cholinergics]	0.529	0.471
T44.0 Anticholinesterase agents	0.529	0.471
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.532	0.467
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.538	0.462
T41.5 Therapeutic gases	0.556	0.444
T41.4 Anaesthetic, unspecified	0.556	0.444
T41.3 Local anaesthetics	0.556	0.444
T41.1 Intravenous anaesthetics	0.556	0.444
T41.0 Inhaled anaesthetics	0.556	0.444
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.558	0.441
T37.5 Antiviral drugs	0.558	0.441
T37.4 Anthelminthics	0.558	0.441
T37.3 Other antiprotozoal drugs	0.558	0.441
T37.1 Antimycobacterial drugs	0.558	0.441
T37.0 Sulphonamides	0.558	0.441
T36.4 Tetracyclines	0.563	0.437
T36.3 Macrolides	0.568	0.431
T39.1 4-Aminophenol derivatives	0.569	0.431
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.570	0.430
T36.9 Systemic antibiotic, unspecified	0.574	0.426
T36.7 Antifungal antibiotics, systemically used	0.574	0.426
T36.6 Rifamycins	0.574	0.426
T36.5 Aminoglycosides	0.574	0.426
T36.2 Chloramphenicol group	0.574	0.426
T37.8 Other specified systemic anti-infectives and antiparasitics	0.574	0.426
T37.2 Antimalarials and drugs acting on other blood protozoa	0.574	0.426
T41.2 Other and unspecified general anaesthetics	0.585	0.415
T36.8 Other systemic antibiotics	0.589	0.411
T40.6 Other and unspecified narcotics	0.595	0.405
T36.0 Penicillins	0.597	0.403
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.602	0.398
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.614	0.386
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.615	0.385
T15-T19 Effects of foreign body entering through natural orifice	0.618	0.382
T18 Foreign body in alimentary tract	0.618	0.382
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.620	0.380
T18.1 Foreign body in oesophagus	0.620	0.380
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.629	0.371
T40.4 Other synthetic narcotics	0.631	0.369
S60-S69 Injuries to the wrist and hand	0.643	0.357
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.644	0.356
T00-T07 Injuries involving multiple body regions	0.648	0.352
S60 Superficial injury of wrist and hand	0.654	0.346
T80 Complications following infusion, transfusion and therapeutic injection	0.660	0.340
T85 Complications of other internal prosthetic devices, implants and grafts	0.665	0.335
T86 Failure and rejection of transplanted organs and tissues	0.665	0.335
S90-S99 Injuries to the ankle and foot	0.674	0.326
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.674	0.325
S60.9 Superficial injury of wrist and hand, unspecified	0.676	0.324
S64 Injury of nerves at wrist and hand level	0.679	0.321
T00 Superficial injuries involving multiple body regions	0.684	0.316
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.690	0.310
T87 Complications peculiar to reattachment and amputation	0.690	0.310
T18.0 Foreign body in mouth	0.692	0.308
T16 Foreign body in ear	0.696	0.304
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.698	0.302
S62 Fracture at wrist and hand level	0.704	0.296
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.706	0.294
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.709	0.291
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.709	0.291
T18.9 Foreign body in alimentary tract, part unspecified	0.716	0.284
S64.1 Injury of median nerve at wrist and hand level	0.717	0.283
T18.3 Foreign body in small intestine	0.717	0.283
T83.2 Mechanical complication of graft of urinary organ	0.717	0.283
S60.2 Contusion of other parts of wrist and hand	0.719	0.281
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.720	0.280
S60.7 Multiple superficial injuries of wrist and hand	0.720	0.280
T26-T28 Burns and corrosions confined to eye and internal organs	0.721	0.279
T18.5 Foreign body in anus and rectum	0.721	0.279
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.722	0.278
T86.8 Failure and rejection of other transplanted organs and tissues	0.722	0.278
T33-T35 Frostbite	0.723	0.277
S64.0 Injury of ulnar nerve at wrist and hand level	0.723	0.277
T19 Foreign body in genito-urinary tract	0.724	0.276
S96 Injury of muscle and tendon at ankle and foot level	0.724	0.276
S66 Injury of muscle and tendon at wrist and hand level	0.725	0.275
T01 Open wounds involving multiple body regions	0.726	0.274
S60.0 Contusion of finger(s) without damage to nail	0.726	0.274
T18.8 Foreign body in other and multiple parts of alimentary tract	0.726	0.274
T18.4 Foreign body in colon	0.726	0.274
T02 Fractures involving multiple body regions	0.726	0.274
T86.0 Bone-marrow transplant rejection	0.726	0.274
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.727	0.273
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.728	0.272
T83.3 Mechanical complication of intra-uterine contraceptive device	0.730	0.270
T15 Foreign body on external eye	0.730	0.270
T83.0 Mechanical complication of urinary (indwelling) catheter	0.730	0.270
S64.3 Injury of digital nerve of thumb	0.732	0.268
S92 Fracture of foot, except ankle	0.732	0.268
T00.9 Multiple superficial injuries, unspecified	0.733	0.267
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.733	0.267
S62.3 Fracture of other metacarpal bone	0.734	0.266
T88 Other complications of surgical and medical care, not elsewhere classified	0.736	0.264
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.737	0.263
S68 Traumatic amputation of wrist and hand	0.739	0.261
T79-T79 Certain early complications of trauma	0.739	0.260
T18.2 Foreign body in stomach	0.740	0.260
S69 Other and unspecified injuries of wrist and hand	0.740	0.260
S91 Open wound of ankle and foot	0.742	0.258
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.742	0.257
T87.6 Other and unspecified complications of amputation stump	0.743	0.257
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.744	0.256
S98 Traumatic amputation of ankle and foot	0.744	0.256
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.746	0.254
T05 Traumatic amputations involving multiple body regions	0.747	0.253
T04 Crushing injuries involving multiple body regions	0.747	0.253
T03 Dislocations, sprains and strains involving multiple body regions	0.747	0.253
T07 Unspecified multiple injuries	0.747	0.253
S62.30 Fracture of other metacarpal bone (closed)	0.749	0.251
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.750	0.250
T00.8 Superficial injuries involving other combinations of body regions	0.750	0.250
S20-S29 Injuries to the thorax	0.753	0.247
S60.8 Other superficial injuries of wrist and hand	0.753	0.247
T06 Other injuries involving multiple body regions, not elsewhere classified	0.753	0.247
S64.7 Injury of multiple nerves at wrist and hand level	0.754	0.246
T80.6 Other serum reactions	0.756	0.244
T80.5 Anaphylactic shock due to serum	0.756	0.244
T80.4 Rh incompatibility reaction	0.756	0.244
T80.3 ABO incompatibility reaction	0.756	0.244
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.756	0.244
S62.6 Fracture of other finger	0.756	0.244
T86.4 Liver transplant failure and rejection	0.759	0.241
T86.3 Heart-lung transplant failure and rejection	0.760	0.240
T86.2 Heart transplant failure and rejection	0.760	0.240
T66-T78 Other and unspecified effects of external causes	0.762	0.238
T87.4 Infection of amputation stump	0.762	0.238
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.762	0.237
S92.3 Fracture of metatarsal bone	0.764	0.236
S65 Injury of blood vessels at wrist and hand level	0.765	0.235
S99 Other and unspecified injuries of ankle and foot	0.765	0.235
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.765	0.235
S95 Injury of blood vessels at ankle and foot level	0.766	0.234
S94 Injury of nerves at ankle and foot level	0.766	0.234
S60.1 Contusion of finger(s) with damage to nail	0.769	0.230
S62.2 Fracture of first metacarpal bone	0.769	0.230
S64.9 Injury of unspecified nerve at wrist and hand level	0.770	0.230
S64.8 Injury of other nerves at wrist and hand level	0.770	0.230
S67 Crushing injury of wrist and hand	0.771	0.229
T17 Foreign body in respiratory tract	0.772	0.228
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.772	0.228
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.773	0.227
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.773	0.227
T00.0 Superficial injuries involving head with neck	0.773	0.227
S62.8 Fracture of other and unspecified parts of wrist and hand	0.776	0.224
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.776	0.224
S27 Injury of other and unspecified intrathoracic organs	0.777	0.223
T87.2 Complications of other reattached body part	0.778	0.222
T87.1 Complications of reattached (part of) lower extremity	0.778	0.222
T87.0 Complications of reattached (part of) upper extremity	0.778	0.222
T20-T25 Burns and corrosions of external body surface, specified by site	0.779	0.221
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.779	0.221
T86.1 Kidney transplant failure and rejection	0.779	0.220
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.780	0.220
S91.2 Open wound of toe(s) with damage to nail	0.780	0.220
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.782	0.218
T01.8 Open wounds involving other combinations of body regions	0.783	0.217
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.784	0.215
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.784	0.215
T87.3 Neuroma of amputation stump	0.785	0.215
S96.8 Injury of other muscles and tendons at ankle and foot level	0.785	0.215
S68.0 Traumatic amputation of thumb (complete)(partial)	0.785	0.214
S97 Crushing injury of ankle and foot	0.786	0.214
S92.30 Fracture of metatarsal bone (closed)	0.787	0.213
T02.8 Fractures involving other combinations of body regions	0.787	0.213
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.787	0.213
T02.4 Fractures involving multiple regions of both upper limbs	0.788	0.212
S91.3 Open wound of other parts of foot	0.788	0.212
S62.7 Multiple fractures of fingers	0.788	0.212
T88.9 Complication of surgical and medical care, unspecified	0.788	0.212
T59 Toxic effect of other gases, fumes and vapours	0.788	0.211
T87.5 Necrosis of amputation stump	0.789	0.211
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.790	0.210
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.790	0.209
T29 Burns and corrosions of multiple body regions	0.791	0.209
T19.0 Foreign body in urethra	0.793	0.207
T15.0 Foreign body in cornea	0.794	0.206
T19.2 Foreign body in vulva and vagina	0.794	0.205
S98.1 Traumatic amputation of one toe	0.795	0.205
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.795	0.205
T85.2 Mechanical complication of intraocular lens	0.797	0.203
T26 Burn and corrosion confined to eye and adnexa	0.797	0.202
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.798	0.202
T30 Burn and corrosion, body region unspecified	0.798	0.202
S92.2 Fracture of other tarsal bone(s)	0.799	0.201
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.800	0.200
T28 Burn and corrosion of other internal organs	0.800	0.200
T27 Burn and corrosion of respiratory tract	0.800	0.200
S62.1 Fracture of other carpal bone(s)	0.800	0.199
T01.3 Open wounds involving multiple regions of lower limb(s)	0.800	0.199
T51 Toxic effect of alcohol	0.801	0.199
T35 Frostbite involving multiple body regions and unspecified frostbite	0.801	0.199
T34 Frostbite with tissue necrosis	0.801	0.199
T33 Superficial frostbite	0.801	0.199
T19.9 Foreign body in genito-urinary tract, part unspecified	0.802	0.198
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.802	0.198
T19.3 Foreign body in uterus [any part]	0.802	0.198
T63 Toxic effect of contact with venomous animals	0.802	0.198
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.802	0.198
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.802	0.198
S92.5 Fracture of other toe	0.802	0.198
S69.7 Multiple injuries of wrist and hand	0.802	0.198
S92.9 Fracture of foot, unspecified	0.803	0.197
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.803	0.197
T32 Corrosions classified according to extent of body surface involved	0.803	0.197
T88.7 Unspecified adverse effect of drug or medicament	0.803	0.197
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.803	0.197
T01.9 Multiple open wounds, unspecified	0.803	0.196
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.803	0.196
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.803	0.196
T01.0 Open wounds involving head with neck	0.803	0.196
T02.9 Multiple fractures, unspecified	0.803	0.196
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.803	0.196
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.803	0.196
T02.3 Fractures involving multiple regions of one lower limb	0.803	0.196
T02.1 Fractures involving thorax with lower back and pelvis	0.803	0.196
T02.0 Fractures involving head with neck	0.803	0.196
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.803	0.196
T54 Toxic effect of corrosive substances	0.804	0.196
T01.2 Open wounds involving multiple regions of upper limb(s)	0.805	0.195
S62.61 Fracture of other finger (open)	0.806	0.194
T15.8 Foreign body in other and multiple parts of external eye	0.806	0.194
S62.4 Multiple fractures of metacarpal bones	0.806	0.193
S62.0 Fracture of navicular [scaphoid] bone of hand	0.807	0.193
T02.5 Fractures involving multiple regions of both lower limbs	0.807	0.193
S50-S59 Injuries to the elbow and forearm	0.808	0.192
T88.3 Malignant hyperthermia due to anaesthesis	0.808	0.192
T83.1 Mechanical complication of other urinary devices and implants	0.808	0.192
T60 Toxic effect of pesticides	0.808	0.192
T57 Toxic effect of other inorganic substances	0.808	0.192
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.808	0.192
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.808	0.192
S62.60 Fracture of other finger (closed)	0.809	0.191
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.809	0.191
S27.1 Traumatic haemothorax	0.809	0.191
T25 Burn and corrosion of ankle and foot	0.809	0.191
T70 Effects of air pressure and water pressure	0.809	0.191
T82.4 Mechanical complication of vascular dialysis catheter	0.810	0.190
S10-S19 Injuries to the neck	0.810	0.190
T88.1 Other complications following immunisation, not elsewhere classified	0.810	0.189
T88.0 Infection following immunisation	0.810	0.189
T68 Hypothermia	0.811	0.189
T31 Burns classified according to extent of body surface involved	0.811	0.189
T61 Toxic effect of noxious substances eaten as seafood	0.812	0.188
T52 Toxic effect of organic solvents	0.812	0.188
S27.2 Traumatic heamopneumothorax	0.812	0.188
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.812	0.188
S92.7 Multiple fractures of foot	0.812	0.188
T15.1 Foreign body in conjunctival sac	0.812	0.188
T56 Toxic effect of metals	0.812	0.188
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.812	0.187
S68.8 Traumatic amputation of other parts of wrist and hand	0.812	0.187
S68.4 Traumatic amputation of hand at wrist level	0.812	0.187
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.812	0.187
T02.2 Fractures involving multiple regions of one upper limb	0.812	0.187
S92.4 Fracture of great toe	0.813	0.187
T55 Toxic effect of soaps and detergents	0.813	0.187
S90 Superficial injury of ankle and foot	0.814	0.186
T62 Toxic effect of other noxious substances eaten as food	0.814	0.186
S92.1 Fracture of talus	0.814	0.186
S91.7 Multiple open wounds of ankle and foot	0.815	0.185
S69.8 Other specified injuries of wrist and hand	0.815	0.185
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.816	0.184
T66 Unspecified effects of radiation	0.816	0.184
S98.4 Traumatic amputation of foot, level unspecified	0.816	0.184
S98.3 Traumatic amputation of other parts of foot	0.816	0.184
S98.2 Traumatic amputation of two or more toes	0.816	0.184
S98.0 Traumatic amputation of foot at ankle level	0.816	0.184
S62.20 Fracture of first metacarpal bone (closed)	0.816	0.183
T19.1 Foreign body in bladder	0.818	0.182
T88.5 Other complications of anaesthesia	0.818	0.182
T03.9 Multiple dislocations, sprains and strains, unspecified	0.818	0.181
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.818	0.181
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.818	0.181
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.818	0.181
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.818	0.181
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.818	0.181
T03.0 Dislocations, sprains and strains involving head with neck	0.818	0.181
T04.9 Multiple crushing injuries, unspecified	0.818	0.181
T04.8 Crushing injuries involving other combinations of body regions	0.818	0.181
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.818	0.181
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.818	0.181
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.818	0.181
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.818	0.181
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.818	0.181
T04.0 Crushing injuries involving head with neck	0.818	0.181
T05.9 Multiple traumatic amputations, unspecified	0.818	0.181
T05.8 Traumatic amputations involving other combinations of body regions	0.818	0.181
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.818	0.181
T05.5 Traumatic amputation of both legs [any level]	0.818	0.181
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.818	0.181
T05.3 Traumatic amputation of both feet	0.818	0.181
T05.2 Traumatic amputation of both arms [any level]	0.818	0.181
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.818	0.181
T05.0 Traumatic amputation of both hands	0.818	0.181
T58 Toxic effect of carbon monoxide	0.820	0.180
T15.9 Foreign body on external eye, unspecified	0.820	0.180
S69.9 Unspecified injury of wrist and hand	0.820	0.180
S26 Injury of heart	0.821	0.179
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.821	0.179
T17.2 Foreign body in pharynx	0.821	0.179
S27.3 Other injuries of lung	0.822	0.178
T59.9 Gases, fumes and vapours, unspecified	0.822	0.178
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.823	0.177
S25 Injury of blood vessels of thorax	0.823	0.177
T06.8 Other specified injuries involving multiple body regions	0.823	0.177
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.823	0.177
T06.3 Injuries of blood vessels involving multiple body regions	0.823	0.177
T06.2 Injuries of nerves involving multiple body regions	0.823	0.177
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.823	0.177
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.823	0.177
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.825	0.175
S64.4 Injury of digital nerve of other finger	0.825	0.175
S65.0 Injury of ulnar artery at wrist and hand level	0.826	0.173
T80.2 Infections following infusion, transfusion and therapeutic injection	0.827	0.173
S65.4 Injury of blood vessel(s) of thumb	0.827	0.172
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.827	0.172
S91.1 Open wound of toe(s) without damage to nail	0.828	0.172
T17.3 Foreign body in larynx	0.828	0.172
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.829	0.171
T06.4 Injuries of muscles and tendons involving multiple body regions	0.829	0.171
T74 Maltreatment syndromes	0.829	0.171
T73 Effects of other deprivation	0.829	0.171
T69 Other effects of reduced temperature	0.829	0.171
T67 Effects of heat and light	0.829	0.171
T79 Certain early complications of trauma, not elsewhere classified	0.829	0.170
S99.9 Unspecified injury of ankle and foot	0.830	0.170
T02.80 Fractures involving other combinations of body regions (closed)	0.830	0.170
S92.31 Fracture of metatarsal bone (open)	0.830	0.169
T65 Toxic effect of other and unspecified substances	0.831	0.169
S20 Superficial injury of thorax	0.831	0.169
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.831	0.168
S65.8 Injury of other blood vessels at wrist and hand level	0.831	0.168
S65.7 Injury of multiple blood vessels at wrist and hand level	0.831	0.168
S65.3 Injury of deep palmar arch	0.831	0.168
S65.2 Injury of superficial palmar arch	0.831	0.168
S99.7 Multiple injuries of ankle and foot	0.831	0.168
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.831	0.168
T51.0 Ethanol	0.832	0.168
S94.9 Injury of unspecified nerve at ankle and foot level	0.832	0.168
S94.8 Injury of other nerves at ankle and foot level	0.832	0.168
S94.7 Injury of multiple nerves at ankle and foot level	0.832	0.168
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.832	0.168
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.832	0.168
S94.1 Injury of medial plantar nerve	0.832	0.168
S94.0 Injury of lateral plantar nerve	0.832	0.168
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.832	0.168
S95.8 Injury of other blood vessels at ankle and foot level	0.832	0.168
S95.7 Injury of multiple blood vessels at ankle and foot level	0.832	0.168
S95.2 Injury of dorsal vein of foot	0.832	0.168
S95.1 Injury of plantar artery of foot	0.832	0.168
S95.0 Injury of dorsal artery of foot	0.832	0.168
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.832	0.168
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.832	0.168
S99.8 Other specified injuries of ankle and foot	0.833	0.167
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.834	0.166
S92.0 Fracture of calcaneus	0.834	0.165
S62.31 Fracture of other metacarpal bone (open)	0.834	0.165
S62.21 Fracture of first metacarpal bone (open)	0.834	0.165
S24 Injury of nerves and spinal cord at thorax level	0.835	0.165
T17.4 Foreign body in trachea	0.836	0.164
T17.1 Foreign body in nostril	0.836	0.164
T17.0 Foreign body in nasal sinus	0.836	0.164
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.837	0.163
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.837	0.163
T82.0 Mechanical complication of heart valve prosthesis	0.838	0.162
S65.5 Injury of blood vessel(s) of other finger	0.838	0.162
T25.2 Burn of second degree of ankle and foot	0.838	0.162
S27.8 Injury of other specified intrathoracic organs	0.839	0.161
S27.9 Injury of unspecified intrathoracic organ	0.840	0.160
S27.7 Multiple injuries of intrathoracic organs	0.840	0.160
S27.6 Injury of pleura	0.840	0.160
S27.5 Injury of thoracic trachea	0.840	0.160
S27.4 Injury of bronchus	0.840	0.160
T88.2 Shock due to anaesthesia	0.840	0.159
T75 Effects of other external causes	0.841	0.159
S93.0 Dislocation of ankle joint	0.841	0.159
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.842	0.158
T71 Asphyxiation	0.842	0.158
T17.5 Foreign body in bronchus	0.843	0.157

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations