TreeWAS – Variant ID: rs4761659

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O73.0 Retained placenta, without haemorrhage	0.000	0.961	0.039
O60-O75 Complications of labour and delivery	0.000	0.961	0.039
O73 Retained placenta and membranes, without haemorrhage	0.000	0.961	0.039
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.963	0.037
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.963	0.037
O70.1 Second degree perineal laceration during delivery	0.000	0.964	0.036
O70 Perineal laceration during delivery	0.000	0.965	0.035
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.966	0.034
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.966	0.034
O61 Failed induction of labour	0.000	0.966	0.034
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.967	0.033
O72 Postpartum haemorrhage	0.000	0.969	0.031
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.969	0.031
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.970	0.030
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.970	0.030
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.970	0.030
O61.0 Failed medical induction of labour	0.000	0.971	0.029
O75.9 Complication of labour and delivery, unspecified	0.000	0.971	0.029
O74 Complications of anaesthesia during labour and delivery	0.000	0.971	0.029
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.971	0.029
O75.0 Maternal distress during labour and delivery	0.000	0.971	0.029
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.971	0.029
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.971	0.029
O60 Preterm delivery	0.000	0.972	0.028
O75.8 Other specified complications of labour and delivery	0.000	0.972	0.028
O64.1 Obstructed labour due to breech presentation	0.000	0.972	0.028
O70.9 Perineal laceration during delivery, unspecified	0.000	0.972	0.028
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.972	0.028
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.973	0.027
O75.4 Other complications of obstetric surgery and procedures	0.000	0.973	0.027
O75.1 Shock during or following labour and delivery	0.000	0.973	0.027
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.973	0.026
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.973	0.026
O69.3 Labour and delivery complicated by short cord	0.000	0.973	0.026
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.973	0.026
O64.5 Obstructed labour due to compound presentation	0.000	0.974	0.026
O75.3 Other infection during labour	0.000	0.974	0.026
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.974	0.026
O71 Other obstetric trauma	0.000	0.974	0.026
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.974	0.026
O69.8 Labour and delivery complicated by other cord complications	0.000	0.974	0.026
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.974	0.026
O61.9 Failed induction of labour, unspecified	0.000	0.974	0.026
O72.1 Other immediate postpartum haemorrhage	0.000	0.975	0.025
O66 Other obstructed labour	0.000	0.975	0.025
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.975	0.025
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.975	0.025
O70.3 Fourth degree perineal laceration during delivery	0.000	0.975	0.024
O61.8 Other failed induction of labour	0.000	0.976	0.024
O61.1 Failed instrumental induction of labour	0.000	0.976	0.024
O64.4 Obstructed labour due to shoulder presentation	0.000	0.976	0.024
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.977	0.023
O64.3 Obstructed labour due to brow presentation	0.000	0.977	0.023
O72.0 Third-stage haemorrhage	0.000	0.977	0.023
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.977	0.023
O64.2 Obstructed labour due to face presentation	0.000	0.977	0.023
O72.3 Postpartum coagulation defects	0.000	0.977	0.023
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.978	0.022
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.978	0.022
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.978	0.022
O71.7 Obstetric haematoma of pelvis	0.000	0.979	0.021
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.979	0.021
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.979	0.021
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.979	0.021
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.979	0.021
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.979	0.021
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.979	0.021
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.979	0.021
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.979	0.021
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.979	0.021
O60.3 Preterm delivery without spontaneous labour	0.000	0.979	0.020
O60.2 Preterm spontaneous labour with term delivery	0.000	0.979	0.020
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.979	0.020
O60.0 Preterm labour without delivery	0.000	0.979	0.020
O66.2 Obstructed labour due to unusually large foetus	0.000	0.980	0.020
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.980	0.020
O67.8 Other intrapartum haemorrhage	0.000	0.980	0.020
O70.2 Third degree perineal laceration during delivery	0.000	0.980	0.020
O71.3 Obstetric laceration of cervix	0.000	0.981	0.019
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.981	0.019
O71.2 Postpartum inversion of uterus	0.000	0.981	0.019
O71.1 Rupture of uterus during labour	0.000	0.981	0.019
O71.0 Rupture of uterus before onset of labour	0.000	0.981	0.019
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.981	0.019
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.981	0.019
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.981	0.019
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.981	0.019
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.981	0.019
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.981	0.019
O65.0 Obstructed labour due to deformed pelvis	0.000	0.981	0.019
O71.5 Other obstetric injury to pelvic organs	0.000	0.981	0.018
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.982	0.018
O66.1 Obstructed labour due to locked twins	0.000	0.982	0.018
O66.9 Obstructed labour, unspecified	0.000	0.982	0.018
O71.9 Obstetric trauma, unspecified	0.000	0.982	0.018
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.982	0.018
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.982	0.018
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.982	0.017
O66.8 Other specified obstructed labour	0.000	0.982	0.017
L03.3 Cellulitis of trunk	0.000	0.983	0.017
O71.8 Other specified obstetric trauma	0.000	0.983	0.016
O62 Abnormalities of forces of labour	0.000	0.983	0.016
O66.4 Failed trial of labour, unspecified	0.000	0.984	0.016
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.984	0.016
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.985	0.015
L03.2 Cellulitis of face	0.000	0.985	0.015
O70.0 First degree perineal laceration during delivery	0.000	0.986	0.014
O63 Long labour	0.000	0.986	0.014
O71.4 Obstetric high vaginal laceration alone	0.000	0.987	0.013
O62.3 Precipitate labour	0.000	0.987	0.013
L03 Cellulitis	0.000	0.987	0.013
O62.0 Primary inadequate contractions	0.000	0.988	0.012
O62.8 Other abnormalities of forces of labour	0.000	0.988	0.012
L03.8 Cellulitis of other sites	0.000	0.988	0.012
D18.0 Haemangioma, any site	0.012	0.988	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.989	0.011
O62.9 Abnormality of forces of labour, unspecified	0.000	0.989	0.011
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.990	0.010
O62.1 Secondary uterine inertia	0.000	0.990	0.010
O63.0 Prolonged first stage (of labour)	0.000	0.991	0.009
O63.9 Long labour, unspecified	0.000	0.991	0.009
O62.2 Other uterine inertia	0.000	0.992	0.008
L03.9 Cellulitis, unspecified	0.000	0.993	0.007
L03.0 Cellulitis of finger and toe	0.000	0.993	0.007
S43.0 Dislocation of shoulder joint	0.000	0.993	0.007
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.005	0.995	0.000
H43.8 Other disorders of vitreous body	0.000	0.996	0.004
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.996	0.004
D18 Haemangioma and lymphangioma, any site	0.004	0.996	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.004	0.996	0.000
H43.3 Other vitreous opacities	0.000	0.996	0.004
C67.9 Bladder, unspecified	0.004	0.996	0.000
H43 Disorders of vitreous body	0.000	0.996	0.004
S32.0 Fracture of lumbar vertebra	0.003	0.996	0.000
C67.1 Dome of bladder	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.000	0.997	0.003
S32.50 Fracture of pubis (closed)	0.003	0.997	0.000
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.003	0.997	0.000
L60.0 Ingrowing nail	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.997	0.003
H44 Disorders of globe	0.000	0.997	0.003
J31.0 Chronic rhinitis	0.000	0.997	0.003
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.997	0.003
H43.2 Crystalline deposits in vitreous body	0.000	0.997	0.003
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
J31.2 Chronic pharyngitis	0.000	0.997	0.003
S64 Injury of nerves at wrist and hand level	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.997	0.003
H44.4 Hypotony of eye	0.000	0.997	0.003
C67.0 Trigone of bladder	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.997	0.003
S32.1 Fracture of sacrum	0.003	0.997	0.000
H44.2 Degenerative myopia	0.000	0.997	0.003
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.000	0.997	0.002
C67.7 Urachus	0.002	0.997	0.000
H44.8 Other disorders of globe	0.000	0.997	0.003
S32.51 Fracture of pubis (open)	0.002	0.997	0.000
D18.1 Lymphangioma, any site	0.002	0.997	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.997	0.002
C67.6 Ureteric orifice	0.002	0.997	0.000
M51.2 Other specified intervertebral disk displacement	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.000	0.997	0.002
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.997	0.002
S32.3 Fracture of ilium	0.002	0.997	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.997	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.002	0.997	0.000
C67.8 Overlapping lesion of bladder	0.002	0.997	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.997	0.002
H44.5 Degenerated conditions of globe	0.000	0.997	0.002
H44.3 Other degenerative disorders of globe	0.000	0.997	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.002
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.998	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.998	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
Y95 Nosocomial condition	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
H44.1 Other endophthalmitis	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.002	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.002	0.998	0.000
L60 Nail disorders	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.002	0.998	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.998	0.002
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
J31.1 Chronic nasopharyngitis	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
H43.1 Vitreous haemorrhage	0.000	0.998	0.002
K11.5 Sialolithiasis	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
L60.8 Other nail disorders	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
L60.1 Onycholysis	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.998	0.002
L60.5 Yellow nail syndrome	0.002	0.998	0.000
L60.4 Beau's lines	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.998	0.002
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.998	0.002
L60.2 Onychogryphosis	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
L60.3 Nail dystrophy	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.998	0.002
K62.1 Rectal polyp	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
K11 Diseases of salivary glands	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
Y57.6 Other diagnostic agents	0.001	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.001	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
K11.3 Abscess of salivary gland	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.001	0.998	0.000
W19.4 Street and highway	0.002	0.998	0.000
Z50.1 Other physical therapy	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.001	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.001	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.001	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.001	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.001	0.998	0.000
S34.3 Injury of cauda equina	0.001	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.001	0.998	0.000
S37 Injury of urinary and pelvic organs	0.001	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.001	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
M51 Other intervertebral disk disorders	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.002	0.998	0.000
K11.0 Atrophy of salivary gland	0.001	0.998	0.000
M51.4 Schmorl's nodes	0.001	0.998	0.000
S36.5 Injury of colon	0.001	0.998	0.000
S36.4 Injury of small intestine	0.001	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.001	0.998	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
K11.4 Fistula of salivary gland	0.001	0.998	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.001	0.998	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.001	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.0 Crushing injury of external genital organs	0.001	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
W50.9 Unspecified place	0.001	0.998	0.000
Y46.4 Iminostilbenes	0.001	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.998	0.000
S31.1 Open wound of abdominal wall	0.001	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.998	0.000
S36.3 Injury of stomach	0.001	0.998	0.000
S36.2 Injury of pancreas	0.001	0.998	0.000
S36.1 Injury of liver or gallbladder	0.001	0.998	0.000
S36.0 Injury of spleen	0.001	0.998	0.000
Y45.1 Salicylates	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.001	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
N90.7 Vulvar cyst	0.001	0.999	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.5 Injury of iliac blood vessels	0.001	0.999	0.000
S35.4 Injury of renal blood vessels	0.001	0.999	0.000
S35.3 Injury of portal or splenic vein	0.001	0.999	0.000
S35.1 Injury of inferior vena cava	0.001	0.999	0.000
S35.0 Injury of abdominal aorta	0.001	0.999	0.000
S36.6 Injury of rectum	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.001	0.999	0.000
N90.3 Dysplasia of vulva, unspecified	0.001	0.999	0.000
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
M51.8 Other specified intervertebral disk disorders	0.001	0.999	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.999	0.001
Q07.0 Arnold-Chiari syndrome	0.000	0.999	0.001
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.001	0.999	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.999	0.000
K11.2 Sialoadenitis	0.001	0.999	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
N90.0 Mild vulvar dysplasia	0.001	0.999	0.000
S31.3 Open wound of scrotum and testes	0.001	0.999	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.001	0.999	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.001	0.999	0.000
S33.4 Traumatic rupture of symphysis pubis	0.001	0.999	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.001	0.999	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.001	0.999	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
S36.50 Injury of colon (without open wound into cavity)	0.001	0.999	0.000
K11.1 Hypertrophy of salivary gland	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
S31.5 Open wound of other and unspecified external genital organs	0.001	0.999	0.000
S35.2 Injury of coeliac or mesenteric artery	0.001	0.999	0.000
S37.9 Injury of unspecified pelvic organ	0.001	0.999	0.000
S37.8 Injury of other pelvic organs	0.001	0.999	0.000
S37.7 Injury of multiple pelvic organs	0.001	0.999	0.000
S37.6 Injury of uterus	0.001	0.999	0.000
S37.5 Injury of Fallopian tube	0.001	0.999	0.000
S37.4 Injury of ovary	0.001	0.999	0.000
S37.3 Injury of urethra	0.001	0.999	0.000
S37.1 Injury of ureter	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.999	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.999	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.999	0.000
Y58.5 Diphtheria vaccine	0.001	0.999	0.000
Y58.4 Tetanus vaccine	0.001	0.999	0.000
Y58.3 Plague vaccine	0.001	0.999	0.000
Y58.2 Cholera vaccine	0.001	0.999	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.999	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
M86.68 Other chronic osteomyelitis (Other)	0.000	0.999	0.001
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
K81.1 Chronic cholecystitis	0.000	0.999	0.001
L29.9 Pruritus, unspecified	0.001	0.999	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.999	0.001
S33.5 Sprain and strain of lumbar spine	0.001	0.999	0.000
S33.1 Dislocation of lumbar vertebra	0.001	0.999	0.000
S36.8 Injury of other intra-abdominal organs	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.999	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.999	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.999	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.999	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.999	0.001
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.001	0.999	0.000
Y41.0 Sulphonamides	0.001	0.999	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
Y53.7 Emetics	0.001	0.999	0.000
Y53.5 Digestants	0.001	0.999	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.999	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.001	0.999	0.000
M86.86 Other osteomyelitis (Lower leg)	0.000	0.999	0.001
S36.51 Injury of colon (with open wound into cavity)	0.001	0.999	0.000
M86.6 Other chronic osteomyelitis	0.000	0.999	0.001
N90.1 Moderate vulvar dysplasia	0.001	0.999	0.000
S31.2 Open wound of penis	0.001	0.999	0.000
S37.2 Injury of bladder	0.001	0.999	0.000
Y41.5 Antiviral drugs	0.001	0.999	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
O42 Premature rupture of membranes	0.000	0.999	0.001
S36.01 Injury of spleen (with open wound into cavity)	0.001	0.999	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.001	0.999	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.001	0.999	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.001	0.999	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.001	0.999	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.001	0.999	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.001	0.999	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.999	0.000
G37.5 Concentric sclerosis [Balo]	0.001	0.999	0.000
G37.4 Subacute necrotising myelitis	0.001	0.999	0.000
G37.2 Central pontine myelinolysis	0.001	0.999	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.999	0.000
G37.0 Diffuse sclerosis	0.001	0.999	0.000
G81.9 Hemiplegia, unspecified	0.001	0.999	0.000
M86.8 Other osteomyelitis	0.000	0.999	0.001
N30.9 Cystitis, unspecified	0.000	0.999	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.999	0.001
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.001	0.999	0.000
Y53.2 Stimulant laxatives	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
Y91.3 Very severe alcohol intoxication	0.001	0.999	0.000
Y91.2 Severe alcohol intoxication	0.001	0.999	0.000
Y91.1 Moderate alcohol intoxication	0.001	0.999	0.000
Y91.0 Mild alcohol intoxication	0.001	0.999	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations