TreeWAS – Variant ID: rs4766646

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.0 Aortic (valve) stenosis	0.000	0.958	0.042
I35 Nonrheumatic aortic valve disorders	0.000	0.966	0.034
I35.9 Aortic valve disorder, unspecified	0.000	0.968	0.032
I35.1 Aortic (valve) insufficiency	0.000	0.971	0.029
I35.8 Other aortic valve disorders	0.000	0.972	0.028
H50.1 Divergent concomitant strabismus	0.022	0.978	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.981	0.019
H50 Other strabismus	0.016	0.984	0.000
H50.0 Convergent concomitant strabismus	0.015	0.985	0.000
F31 Bipolar affective disorder	0.014	0.986	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.014	0.986	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.014	0.986	0.000
F31.9 Bipolar affective disorder, unspecified	0.013	0.987	0.000
H50.8 Other specified strabismus	0.013	0.987	0.000
H50.2 Vertical strabismus	0.013	0.987	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.012	0.988	0.000
H50.3 Intermittent heterotropia	0.012	0.988	0.000
H50.6 Mechanical strabismus	0.011	0.989	0.000
H50.4 Other and unspecified heterotropia	0.011	0.989	0.000
H50.5 Heterophoria	0.011	0.989	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.011	0.989	0.000
H50.9 Strabismus, unspecified	0.011	0.989	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.011	0.989	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
C50.2 Upper-inner quadrant of breast	0.010	0.990	0.000
F31.8 Other bipolar affective disorders	0.010	0.990	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.010	0.990	0.000
N03.9 Unspecified	0.000	0.990	0.010
F31.7 Bipolar affective disorder, currently in remission	0.009	0.991	0.000
D09.0 Bladder	0.000	0.992	0.008
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
K31.7 Polyp of stomach and duodenum	0.000	0.992	0.008
F31.0 Bipolar affective disorder, current episode hypomanic	0.008	0.992	0.000
O16 Unspecified maternal hypertension	0.008	0.992	0.000
N03 Chronic nephritic syndrome	0.000	0.993	0.007
N03.1 Focal and segmental glomerular lesions	0.000	0.993	0.007
O15 Eclampsia	0.007	0.993	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.007	0.993	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.993	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.006	0.994	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.994	0.006
N03.8 Other	0.000	0.994	0.006
O14.9 Preeclampsia, unspecified	0.006	0.994	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O15.2 Eclampsia in the puerperium	0.005	0.994	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.994	0.005
N03.6 Dense deposit disease	0.000	0.994	0.005
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.994	0.005
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.994	0.005
N03.0 Minor glomerular abnormality	0.000	0.994	0.005
O12.1 Gestational proteinuria	0.005	0.995	0.000
I89.1 Lymphangitis	0.005	0.995	0.000
O15.9 Eclampsia, unspecified as to time period	0.005	0.995	0.000
O15.1 Eclampsia in labour	0.005	0.995	0.000
O15.0 Eclampsia in pregnancy	0.005	0.995	0.000
O14.2 HELLP syndrome	0.005	0.995	0.000
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
N03.2 Diffuse membranous glomerulonephritis	0.000	0.995	0.005
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.995	0.005
O14.1 Severe preeclampsia	0.005	0.995	0.000
B18.2 Chronic viral hepatitis C	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.004	0.996	0.000
F30-F39 Mood [affective] disorders	0.004	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
F34 Persistent mood [affective] disorders	0.004	0.996	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.004	0.996	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.996	0.004
K72.9 Hepatic failure, unspecified	0.000	0.996	0.004
F34.1 Dysthymia	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
F39 Unspecified mood [affective] disorder	0.004	0.996	0.000
Z30.2 Sterilisation	0.004	0.996	0.000
F34.0 Cyclothymia	0.004	0.996	0.000
O12.0 Gestational oedema	0.004	0.996	0.000
R57.2 Septic shock	0.000	0.996	0.004
L89 Decubitus ulcer	0.000	0.996	0.004
F33 Recurrent depressive disorder	0.003	0.997	0.000
K00.6 Disturbances in tooth eruption	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.997	0.003
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
J01.9 Acute sinusitis, unspecified	0.003	0.997	0.000
R57.0 Cardiogenic shock	0.000	0.997	0.003
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.997	0.003
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.003	0.997	0.000
B18 Chronic viral hepatitis	0.000	0.997	0.003
F38 Other mood [affective] disorders	0.003	0.997	0.000
S32.40 Fracture of acetabulum (closed)	0.003	0.997	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.997	0.003
L89.3 Stage IV decubitus ulcer	0.000	0.997	0.003
R57 Shock, not elsewhere classified	0.000	0.997	0.003
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.003
H25.0 Senile incipient cataract	0.003	0.997	0.000
J46 Status asthmaticus	0.003	0.997	0.000
R57.9 Shock, unspecified	0.000	0.997	0.003
R32 Unspecified urinary incontinence	0.000	0.997	0.003
N39.4 Other specified urinary incontinence	0.000	0.997	0.003
F30 Manic episode	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
D09.7 Carcinoma in situ of other specified sites	0.000	0.997	0.003
D09.3 Thyroid and other endocrine glands	0.000	0.997	0.003
D09.2 Eye	0.000	0.997	0.003
D10.1 Tongue	0.000	0.997	0.003
Z01.6 Radiological examination, not elsewhere classified	0.003	0.997	0.000
D09.9 Carcinoma in situ, unspecified	0.000	0.997	0.003
D09.1 Other and unspecified urinary organs	0.000	0.997	0.003
M25.78 Osteophyte (Other)	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
B18.8 Other chronic viral hepatitis	0.000	0.997	0.002
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.997	0.002
F38.1 Other recurrent mood [affective] disorders	0.002	0.997	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
N13.4 Hydroureter	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
R57.8 Other shock	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.998	0.002
F30.8 Other manic episodes	0.002	0.998	0.000
R57.1 Hypovolaemic shock	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.998	0.002
F30.0 Hypomania	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.998	0.002
K38.1 Appendicular concretions	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
K38 Other diseases of appendix	0.002	0.998	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
K38.2 Diverticulum of appendix	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
H25.9 Senile cataract, unspecified	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
J01 Acute sinusitis	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.998	0.002
K38.9 Disease of appendix, unspecified	0.002	0.998	0.000
J01.1 Acute frontal sinusitis	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
K38.0 Hyperplasia of appendix	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
J01.2 Acute ethmoidal sinusitis	0.002	0.998	0.000
J01.0 Acute maxillary sinusitis	0.002	0.998	0.000
K38.3 Fistula of appendix	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.002
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.002
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.002
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.002
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.002
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.001	0.998	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.002	0.998	0.000
J01.3 Acute sphenoidal sinusitis	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
W06.0 Home	0.000	0.998	0.002
H49 Paralytic strabismus	0.002	0.998	0.000
J01.8 Other acute sinusitis	0.002	0.998	0.000
W13.9 Unspecified place	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.998	0.001
F05.8 Other delirium	0.000	0.998	0.002
O00.1 Tubal pregnancy	0.000	0.998	0.002
J01.4 Acute pansinusitis	0.001	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
G72.9 Myopathy, unspecified	0.000	0.998	0.002
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.001
Q43.0 Meckel's diverticulum	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.001
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
S32.41 Fracture of acetabulum (open)	0.001	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.001	0.998	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.001
G72.8 Other specified myopathies	0.000	0.998	0.001
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.001
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.001
H49.3 Total (external) ophthalmoplegia	0.001	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.999	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
M95.0 Acquired deformity of nose	0.000	0.999	0.001
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
K72.1 Chronic hepatic failure	0.000	0.999	0.001
H25 Senile cataract	0.001	0.999	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.999	0.001
E07.9 Disorder of thyroid, unspecified	0.001	0.999	0.000
H49.8 Other paralytic strabismus	0.001	0.999	0.000
D26.9 Uterus, unspecified	0.000	0.999	0.001
S52.00 Fracture of upper end of ulna (closed)	0.000	0.999	0.001
C49.4 Connective and soft tissue of abdomen	0.000	0.999	0.001
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
M06.8 Other specified rheumatoid arthritis	0.000	0.999	0.001
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
M19.93 Arthrosis, unspecified (Forearm)	0.001	0.999	0.000
G72 Other myopathies	0.000	0.999	0.001
M06 Other rheumatoid arthritis	0.000	0.999	0.001
H49.4 Progressive external ophthalmoplegia	0.001	0.999	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.999	0.001
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.999	0.000
G72.1 Alcoholic myopathy	0.000	0.999	0.001
R76.0 Raised antibody titer	0.000	0.999	0.001
R76 Other abnormal immunological findings in serum	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
B19.9 Unspecified viral hepatitis without coma	0.000	0.999	0.001
H25.2 Senile cataract, morgagnian type	0.001	0.999	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.001	0.999	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.999	0.001
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.999	0.001
N76.0 Acute vaginitis	0.001	0.999	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.999	0.001
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.999	0.001
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
G71.1 Myotonic disorders	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.000	0.999	0.001
R70.1 Abnormal plasma viscosity	0.000	0.999	0.001
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
C84.0 Mycosis fungoides	0.001	0.999	0.000
G71.0 Muscular dystrophy	0.000	0.999	0.001
H27.0 Aphakia	0.001	0.999	0.000
M06.2 Rheumatoid bursitis	0.000	0.999	0.001
M06.1 Adult-onset Still's disease	0.000	0.999	0.001
M25.72 Osteophyte (Upper arm)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.999	0.001
F05.1 Delirium superimposed on dementia	0.000	0.999	0.001
G72.3 Periodic paralysis	0.000	0.999	0.001
G72.2 Myopathy due to other toxic agents	0.000	0.999	0.001
H49.9 Paralytic strabismus, unspecified	0.001	0.999	0.000
H49.2 Sixth [abducent] nerve palsy	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.999	0.001
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.999	0.001
B19 Unspecified viral hepatitis	0.000	0.999	0.001
C49.3 Connective and soft tissue of thorax	0.000	0.999	0.001
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
H27.8 Other specified disorders of lens	0.001	0.999	0.000
R76.2 False-positive serological test for syphilis	0.000	0.999	0.001
R76.1 Abnormal reaction to tuberculin test	0.000	0.999	0.001
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.001	0.999	0.000
Y40.3 Macrolides	0.000	0.999	0.001
Y65.4 Failure to introduce or to remove other tube or instrument	0.001	0.999	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
M25.76 Osteophyte (Lower leg)	0.001	0.999	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.999	0.001
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.999	0.001
I24.8 Other forms of acute ischaemic heart disease	0.001	0.999	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.001	0.999	0.000
Q74.1 Congenital malformation of knee	0.001	0.999	0.000
S06.3 Focal brain injury	0.001	0.999	0.000
B16 Acute hepatitis B	0.000	0.999	0.001
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.999	0.001
M06.18 Adult-onset Still's disease (Other)	0.000	0.999	0.001
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.999	0.001
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.999	0.001
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.999	0.001
M06.14 Adult-onset Still's disease (Hand)	0.000	0.999	0.001
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.999	0.001
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.999	0.001
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.999	0.001
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.999	0.001
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.999	0.001
M06.28 Rheumatoid bursitis (Other)	0.000	0.999	0.001
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.999	0.001
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.999	0.001
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.999	0.001
M06.24 Rheumatoid bursitis (Hand)	0.000	0.999	0.001
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.999	0.001
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.999	0.001
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.999	0.001
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.999	0.001
C81.1 Nodular sclerosis	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
B15-B19 Viral hepatitis	0.000	0.999	0.001
B19.0 Unspecified viral hepatitis with coma	0.000	0.999	0.001
C44.4 Skin of scalp and neck	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
G71 Primary disorders of muscles	0.000	0.999	0.001
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.999	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.999	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.999	0.000
T93.2 Sequelae of other fractures of lower limb	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.000	0.999	0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.999	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.999	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.999	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.999	0.001
D35.1 Parathyroid gland	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.999	0.001
T88.5 Other complications of anaesthesia	0.001	0.999	0.000
Y65 Other misadventures during surgical and medical care	0.001	0.999	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.999	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.999	0.001
G71.8 Other primary disorders of muscles	0.000	0.999	0.001
G71.2 Congenital myopathies	0.000	0.999	0.001
H40.8 Other glaucoma	0.001	0.999	0.000
T20.1 Burn of first degree of head and neck	0.001	0.999	0.000
Z63.4 Disappearance and death of family member	0.001	0.999	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.999	0.001
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.999	0.001
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.999	0.001
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.999	0.001
G72.0 Drug-induced myopathy	0.000	0.999	0.001
N81.8 Other female genital prolapse	0.001	0.999	0.000
S06.1 Traumatic cerebral oedema	0.001	0.999	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.999	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
S42.00 Fracture of clavicle (closed)	0.001	0.999	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.999	0.001
H40.4 Glaucoma secondary to eye inflammation	0.001	0.999	0.000
L12.1 Cicatricial pemphigoid	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.000	0.999	0.001
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
Y65.5 Performance of inappropriate operation	0.001	0.999	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.001	0.999	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.001	0.999	0.000
Y65.1 Wrong fluid used in infusion	0.001	0.999	0.000
Y65.0 Mismatched blood used in transfusion	0.001	0.999	0.000
F03 Unspecified dementia	0.000	0.999	0.001
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.999	0.001
J00 Acute nasopharyngitis [common cold]	0.000	0.999	0.001
Q43 Other congenital malformations of intestine	0.000	0.999	0.001
Y40 Systemic antibiotics	0.000	0.999	0.001
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.999	0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.999	0.001
F02.2 Dementia in Huntington's disease	0.000	0.999	0.001
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.999	0.001
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.999	0.001
M22.2 Patellofemoral disorders	0.000	0.999	0.001
Z80.3 Family history of malignant neoplasm of breast	0.000	0.999	0.001
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
S06 Intracranial injury	0.001	0.999	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.999	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.999	0.001
G44.8 Other specified headache syndromes	0.001	0.999	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.999	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.999	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.999	0.001
Q43.7 Persistent cloaca	0.000	0.999	0.001
Q43.6 Congenital fistula of rectum and anus	0.000	0.999	0.001
Q43.5 Ectopic anus	0.000	0.999	0.001
Q43.4 Duplication of intestine	0.000	0.999	0.001
Q43.2 Other congenital functional disorders of colon	0.000	0.999	0.001
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Y40.4 Tetracyclines	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
M25.79 Osteophyte (Site unspecified)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
D43.1 Brain, infratentorial	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.999	0.001
F07.1 Postencephalitic syndrome	0.000	0.999	0.001
L85.8 Other specified epidermal thickening	0.000	0.999	0.001
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.999	0.000
S06.7 Intracranial injury with prolonged coma	0.001	0.999	0.000
Y40.5 Aminoglycosides	0.000	0.999	0.001
Z50.1 Other physical therapy	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.999	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.999	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
G90.3 Multisystem degeneration	0.000	0.999	0.001
H28.0 Diabetic cataract	0.001	0.999	0.000
M95.1 Cauliflower ear	0.000	0.999	0.001
Q43.3 Congenital malformations of intestinal fixation	0.000	0.999	0.001
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
S81.0 Open wound of knee	0.001	0.999	0.000
Y40.6 Rifamycins	0.000	0.999	0.001
C84 Peripheral and cutaneous T-cell lymphomas	0.001	0.999	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.999	0.001
M25.73 Osteophyte (Forearm)	0.001	0.999	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.001	0.999	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.001	0.999	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.001	0.999	0.000
C84.3 Lymphoepithelioid lymphoma	0.001	0.999	0.000
C84.2 T-zone lymphoma	0.001	0.999	0.000
C84.1 Sezary's diease	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.001	0.999	0.000
I87.8 Other specified disorders of veins	0.000	0.999	0.001
M25.7 Osteophyte	0.001	0.999	0.000
H27 Other disorders of lens	0.001	0.999	0.000
M25.70 Osteophyte (Multiple sites)	0.001	0.999	0.000
M77.02 Medial epicondylitis (Upper arm)	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.999	0.000
C00.9 Lip, unspecified	0.001	0.999	0.000
C81.0 Lymphocytic predominance	0.001	0.999	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
F07.0 Organic personality disorder	0.000	0.999	0.001
G91.8 Other hydrocephalus	0.001	0.999	0.000
G94.1 Hydrocephalus in neoplastic disease	0.001	0.999	0.000
H27.9 Disorder of lens, unspecified	0.001	0.999	0.000
L12.9 Pemphigoid, unspecified	0.001	0.999	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.999	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.999	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.999	0.000
R82.4 Acetonuria	0.001	0.999	0.000
Y44.2 Anticoagulants	0.000	0.999	0.001
Z99.2 Dependence on renal dialysis	0.000	0.999	0.001
Q74 Other congenital malformations of limb(s)	0.001	0.999	0.000
S06.01 Concussion (with open intracranial wound)	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
C81.9 Hodgkin's disease, unspecified	0.001	0.999	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.001	0.999	0.000
K00.7 Teething syndrome	0.001	0.999	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.001	0.999	0.000
K00.4 Disturbances in tooth formation	0.001	0.999	0.000
K00.3 Mottled teeth	0.001	0.999	0.000
K00.2 Abnormalities of size and form of teeth	0.001	0.999	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.001	0.999	0.000
N76.6 Ulceration of vulva	0.001	0.999	0.000
S06.9 Intracranial injury, unspecified	0.001	0.999	0.000
S06.4 Epidural haemorrhage	0.001	0.999	0.000
S06.0 Concussion	0.001	0.999	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
Z01.7 Laboratory examination	0.001	0.999	0.000
K00 Disorders of tooth development and eruption	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations