TreeWAS – Variant ID: rs4799088

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R20.2 Paraesthesia of skin	0.118	0.882	0.000
R20 Disturbances of skin sensation	0.106	0.894	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.099	0.901	0.000
R20.0 Anaesthesia of skin	0.094	0.906	0.000
R20.3 Hyperaesthesia	0.081	0.918	0.000
R20.1 Hypoaesthesia of skin	0.076	0.924	0.000
R07.4 Chest pain, unspecified	0.059	0.941	0.000
X41.9 Unspecified place	0.010	0.990	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.009	0.991	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.992	0.008
R04.2 Haemoptysis	0.008	0.992	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.008	0.992	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.007	0.993	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.006	0.994	0.000
R81 Glycosuria	0.006	0.994	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.006	0.994	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.006	0.994	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.006	0.994	0.000
E87.7 Fluid overload	0.000	0.995	0.005
E28.2 Polycystic ovarian syndrome	0.005	0.995	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.005	0.995	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.005	0.995	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.005	0.995	0.000
R04 Haemorrhage from respiratory passages	0.005	0.995	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.005	0.995	0.000
R80 Isolated proteinuria	0.005	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.995	0.005
D37.4 Colon	0.004	0.996	0.000
J15.1 Pneumonia due to Pseudomonas	0.000	0.996	0.004
R04.0 Epistaxis	0.004	0.996	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.004	0.996	0.000
R82.9 Other and unspecified abnormal finding in urine	0.004	0.996	0.000
E28 Ovarian dysfunction	0.004	0.996	0.000
R82 Other abnormal findings in urine	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.004	0.996	0.000
D23.5 Skin of trunk	0.004	0.996	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.004	0.996	0.000
M65.8 Other synovitis and tenosynovitis	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
M65 Synovitis and tenosynovitis	0.004	0.996	0.000
X41.0 Home	0.004	0.996	0.000
X41.8 Other specified place	0.004	0.996	0.000
X41.7 Farm	0.004	0.996	0.000
X41.6 Industrial and construction area	0.004	0.996	0.000
X41.5 Trade and service area	0.004	0.996	0.000
X41.4 Street and highway	0.004	0.996	0.000
X41.3 Sports and athletics area	0.004	0.996	0.000
X41.2 School, other institution and public administrative area	0.004	0.996	0.000
X41.1 Residential institution	0.004	0.996	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.004	0.996	0.000
K83.1 Obstruction of bile duct	0.000	0.996	0.004
R04.9 Haemorrhage from respiratory passages, unspecified	0.004	0.996	0.000
R04.1 Haemorrhage from throat	0.004	0.996	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.996	0.004
O70.1 Second degree perineal laceration during delivery	0.000	0.996	0.004
T90.2 Sequelae of fracture of skull and facial bones	0.004	0.996	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.003	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.996	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
R82.4 Acetonuria	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R82.3 Haemoglobinuria	0.003	0.997	0.000
R82.2 Biliuria	0.003	0.997	0.000
R82.0 Chyluria	0.003	0.997	0.000
E14.9 Without complications	0.003	0.997	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.997	0.003
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
R07 Pain in throat and chest	0.003	0.997	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.003	0.997	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
O26.2 Pregnancy care of habitual aborter	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.003	0.997	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.003	0.997	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.003	0.997	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.003	0.997	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.997	0.003
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
M65.2 Calcific tendinitis	0.003	0.997	0.000
M65.0 Abscess of tendon sheath	0.003	0.997	0.000
R82.1 Myoglobinuria	0.003	0.997	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.003	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.003	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.003	0.997	0.000
R07.1 Chest pain on breathing	0.003	0.997	0.000
O26.5 Maternal hypotension syndrome	0.003	0.997	0.000
T51.0 Ethanol	0.003	0.997	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.003	0.997	0.000
J15.5 Pneumonia due to Escherichia coli	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
M65.1 Other infective (teno)synovitis	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.997	0.003
K59.1 Functional diarrhoea	0.003	0.997	0.000
O20.0 Threatened abortion	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997	0.000
O26.4 Herpes gestationis	0.003	0.997	0.000
O26.1 Low weight gain in pregnancy	0.003	0.997	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.003	0.997	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.003	0.997	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.002	0.997	0.000
O21 Excessive vomiting in pregnancy	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.997	0.000
D37.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.002	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.997	0.000
E26.0 Primary hyperaldosteronism	0.002	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.997	0.000
E31.8 Other polyglandular dysfunction	0.002	0.997	0.000
E31.1 Polyglandular hyperfunction	0.002	0.997	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.997	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.002	0.997	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.997	0.002
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.997	0.002
J15.3 Pneumonia due to streptococcus, group B	0.000	0.997	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.002	0.998	0.000
M65.08 Abscess of tendon sheath (Other)	0.002	0.998	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.002	0.998	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.002	0.998	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.002	0.998	0.000
M65.04 Abscess of tendon sheath (Hand)	0.002	0.998	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.002	0.998	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.002	0.998	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.002	0.998	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.002	0.998	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.002	0.998	0.000
M65.28 Calcific tendinitis (Other)	0.002	0.998	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.002	0.998	0.000
M65.26 Calcific tendinitis (Lower leg)	0.002	0.998	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.24 Calcific tendinitis (Hand)	0.002	0.998	0.000
M65.23 Calcific tendinitis (Forearm)	0.002	0.998	0.000
M65.22 Calcific tendinitis (Upper arm)	0.002	0.998	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.002	0.998	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
J15.4 Pneumonia due to other streptococci	0.000	0.998	0.002
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.002	0.998	0.000
M65.18 Other infective (teno)synovitis (Other)	0.002	0.998	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.002	0.998	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.002	0.998	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.002	0.998	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.002	0.998	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.002	0.998	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.002	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.002	0.998	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.002	0.998	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.002	0.998	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.002	0.998	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.000	0.998	0.002
E29 Testicular dysfunction	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
T65.9 Toxic effect of unspecified substance	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
M65.3 Trigger finger	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.002	0.998	0.000
C43 Malignant melanoma of skin	0.000	0.998	0.002
T51 Toxic effect of alcohol	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.001	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.002	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.002	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.002	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.002	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.002	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
D37.3 Appendix	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.001	0.998	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.002	0.998	0.000
M65.38 Trigger finger-Other	0.002	0.998	0.000
M65.37 Trigger finger-Ankle/foot	0.002	0.998	0.000
M65.36 Trigger finger-Lower leg	0.002	0.998	0.000
M65.35 Trigger finger-Pelvic/thigh	0.002	0.998	0.000
M65.33 Trigger finger-Forearm	0.002	0.998	0.000
M65.32 Trigger finger-Upper arm	0.002	0.998	0.000
M65.31 Trigger finger-Shldr region	0.002	0.998	0.000
M65.30 Trigger finger-Mult sites	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
E14.5 With peripheral circulatory complications	0.002	0.998	0.000
E14.4 With neurological complications	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
C43.8 Overlapping malignant melanoma of skin	0.000	0.998	0.002
C43.0 Malignant melanoma of lip	0.000	0.998	0.002
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
T51.8 Other alcohols	0.002	0.998	0.000
T51.3 Fusel oil	0.002	0.998	0.000
T51.2 2-Propanol	0.002	0.998	0.000
T51.1 Methanol	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.001
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
E34.9 Endocrine disorder, unspecified	0.001	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
T65 Toxic effect of other and unspecified substances	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
E14.2 Withrenal complications	0.001	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.000	0.998	0.002
E14.7 With multiple complications	0.001	0.998	0.000
E14.0 With coma	0.001	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.998	0.000
S92.0 Fracture of calcaneus	0.001	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.002
E14.8 With unspecified complications	0.001	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.001	0.998	0.000
O22.8 Other venous complications in pregnancy	0.001	0.998	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.998	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.998	0.000
O22.1 Genital varices in pregnancy	0.001	0.998	0.000
K83 Other diseases of biliary tract	0.000	0.998	0.002
M65-M68 Disorders of synovium and tendon	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.001
E14.6 With other specified complications	0.001	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.001	0.998	0.000
T51.9 Alcohol, unspecified	0.001	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.001	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.002	0.998	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.001	0.998	0.000
M95.5 Acquired deformity of pelvis	0.001	0.998	0.000
M95.3 Acquired deformity of neck	0.001	0.998	0.000
M95.1 Cauliflower ear	0.001	0.998	0.000
Q66.8 Other congenital deformities of feet	0.000	0.998	0.001
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.001	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.999	0.001
D37.2 Small intestine	0.001	0.999	0.000
E24.9 Cushing's syndrome, unspecified	0.001	0.999	0.001
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
E14.3 With ophthalmic complications	0.001	0.999	0.000
G41.9 Status epilepticus, unspecified	0.000	0.999	0.001
M95.4 Acquired deformity of chest and rib	0.001	0.999	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.999	0.001
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.999	0.001
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
F17.2 Dependence syndrome	0.001	0.999	0.000
O75.0 Maternal distress during labour and delivery	0.000	0.999	0.001
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T65.8 Toxic effect of other specified substances	0.001	0.999	0.000
T65.6 Paints and dyes, not elsewhere classified	0.001	0.999	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.001	0.999	0.000
T65.4 Carbon disulphide	0.001	0.999	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.001	0.999	0.000
T65.2 Tobacco and nicotine	0.001	0.999	0.000
T65.1 Strychnine and its salts	0.001	0.999	0.000
T65.0 Cyanides	0.001	0.999	0.000
R07.0 Pain in throat	0.001	0.999	0.000
F11.2 Dependence syndrome	0.000	0.999	0.001
I74.8 Embolism and thrombosis of other arteries	0.001	0.999	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.001	0.999	0.000
O22.4 Haemorrhoids in pregnancy	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
E14.1 With ketoacidosis	0.001	0.999	0.000
E16.1 Other hypoglycaemia	0.001	0.999	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
O22.0 Varicose veins of lower extremity in pregnancy	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
X59.2 School, other institution and public administrative area	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.001	0.999	0.000
T59 Toxic effect of other gases, fumes and vapours	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.999	0.001
C83.3 Large cell (diffuse)	0.000	0.999	0.001
K83.5 Biliary cyst	0.000	0.999	0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.001	0.999	0.000
M96.5 Postradiation scoliosis	0.001	0.999	0.000
M96.4 Postsurgical lordosis	0.001	0.999	0.000
M96.3 Postlaminectomy kyphosis	0.001	0.999	0.000
M96.2 Postradiation kyphosis	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.999	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.999	0.000
R61.0 Localised hyperhidrosis	0.001	0.999	0.000
B17.2 Acute hepatitis E	0.001	0.999	0.000
E13.9 Without complications	0.000	0.999	0.001
I89.1 Lymphangitis	0.000	0.999	0.001
K83.0 Cholangitis	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
E16 Other disorders of pancreatic internal secretion	0.001	0.999	0.000
M24.02 Loose body in joint (Upper arm)	0.001	0.999	0.000
B35.1 Tinea unguium	0.001	0.999	0.000
G94.1 Hydrocephalus in neoplastic disease	0.001	0.999	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.001	0.999	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999	0.000
B17.8 Other specified acute viral hepatitis	0.001	0.999	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
D37.6 Liver, gallbladder and bile ducts	0.001	0.999	0.000
G95.9 Disease of spinal cord, unspecified	0.001	0.999	0.000
X59.3 Sports and athletics area	0.001	0.999	0.000
K83.3 Fistula of bile duct	0.000	0.999	0.001
M96.0 Pseudarthrosis after fusion or arthrodesis	0.001	0.999	0.000
B17 Other acute viral hepatitis	0.001	0.999	0.000
M67 Other disorders of synovium and tendon	0.001	0.999	0.000
R23 Other skin changes	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.999	0.001
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
I37.1 Pulmonary valve insufficiency	0.001	0.999	0.000
J32.4 Chronic pansinusitis	0.001	0.999	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.001	0.999	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
T59.9 Gases, fumes and vapours, unspecified	0.001	0.999	0.000
T59.7 Carbon dioxide	0.001	0.999	0.000
T59.6 Hydrogen sulphide	0.001	0.999	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.001	0.999	0.000
T59.4 Chlorine gas	0.001	0.999	0.000
T59.3 Lachrymogenic gas	0.001	0.999	0.000
T59.2 Formaldehyde	0.001	0.999	0.000
T59.1 Sulphur dioxide	0.001	0.999	0.000
T59.0 Nitrogen oxides	0.001	0.999	0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.001	0.999	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.001	0.999	0.000
M95.2 Other acquired deformity of head	0.001	0.999	0.000
O75.9 Complication of labour and delivery, unspecified	0.000	0.999	0.001
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.999	0.001
O75.4 Other complications of obstetric surgery and procedures	0.000	0.999	0.001
O75.3 Other infection during labour	0.000	0.999	0.001
O75.1 Shock during or following labour and delivery	0.000	0.999	0.001
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.999	0.001
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
O23 Infections of genito-urinary tract in pregnancy	0.001	0.999	0.000
M54.59 Low back pain (Site unspecified)	0.001	0.999	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.999	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.999	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.999	0.000
E16.3 Increased secretion of glucagon	0.001	0.999	0.000
G03.9 Meningitis, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations