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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4818225
log Bayes Factor = 0.171213
Chromosome 21   position 42,629,895  (GRCh37) Explore rs4818225 on Ensembl!
Variant rs4818225 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.346 0.654 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.062 0.938 0.000
C83.3 Large cell (diffuse)
0.062 0.938 0.000
C83.0 Small cell (diffuse)
0.062 0.938 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.054 0.946 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.054 0.946 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.053 0.947 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.051 0.949 0.000
M06.9 Rheumatoid arthritis, unspecified
0.050 0.950 0.000
C83.1 Small cleaved cell (diffuse)
0.047 0.953 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.046 0.954 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.045 0.955 0.000
C83.6 Undifferentiated (diffuse)
0.045 0.955 0.000
C83.5 Lymphoblastic (diffuse)
0.045 0.955 0.000
C83.4 Immunoblastic (diffuse)
0.045 0.955 0.000
C83.2 Mixed small and large cell (diffuse)
0.045 0.955 0.000
T82.1 Mechanical complication of cardiac electronic device
0.045 0.955 0.000
C83.7 Burkitt's tumour
0.043 0.957 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.041 0.959 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.041 0.959 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.040 0.960 0.000
F31 Bipolar affective disorder
0.000 0.964 0.036
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.964 0.036
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.036 0.964 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.034 0.965 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.034 0.966 0.000
D13.1 Stomach
0.034 0.966 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.034 0.966 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.034 0.966 0.000
K55.2 Angiodysplasia of colon
0.034 0.966 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.033 0.967 0.000
T82.3 Mechanical complication of other vascular grafts
0.032 0.967 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.032 0.968 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.032 0.968 0.000
M06 Other rheumatoid arthritis
0.031 0.969 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.969 0.031
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.969 0.031
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.969 0.031
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.030 0.970 0.000
F31.9 Bipolar affective disorder, unspecified
0.000 0.970 0.030
F31.7 Bipolar affective disorder, currently in remission
0.000 0.971 0.029
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.028 0.971 0.000
M06.3 Rheumatoid nodule
0.028 0.972 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.972 0.028
F31.8 Other bipolar affective disorders
0.000 0.972 0.028
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.974 0.026
M06.1 Adult-onset Still's disease
0.025 0.975 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.024 0.976 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.976 0.024
F33.9 Recurrent depressive disorder, unspecified
0.000 0.976 0.024
M06.0 Seronegative rheumatoid arthritis
0.024 0.976 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.023 0.977 0.000
M06.2 Rheumatoid bursitis
0.023 0.977 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.022 0.977 0.000
M06.8 Other specified rheumatoid arthritis
0.022 0.978 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.022 0.978 0.000
O48 Prolonged pregnancy
0.000 0.979 0.021
M06.37 Rheumatoid nodule (Ankle and foot)
0.021 0.979 0.000
D13.5 Extrahepatic bile ducts
0.021 0.979 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.020 0.979 0.000
M06.38 Rheumatoid nodule (Other)
0.020 0.979 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.020 0.979 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.020 0.979 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.020 0.980 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.000 0.980 0.020
F33 Recurrent depressive disorder
0.000 0.980 0.020
M06.34 Rheumatoid nodule (Hand)
0.020 0.980 0.000
F30-F39 Mood [affective] disorders
0.000 0.980 0.020
O47 False labour
0.000 0.980 0.020
M06.33 Rheumatoid nodule (Forearm)
0.019 0.981 0.000
O43 Placental disorders
0.000 0.981 0.019
O47.0 False labour before 37 completed weeks of gestation
0.000 0.981 0.019
M06.19 Adult-onset Still's disease (Site unspecified)
0.019 0.981 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.019 0.981 0.000
O30 Multiple gestation
0.000 0.981 0.019
M06.04 Seronegative rheumatoid arthritis (Hand)
0.018 0.982 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.018 0.982 0.000
M06.18 Adult-onset Still's disease (Other)
0.018 0.982 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.018 0.982 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.018 0.982 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.018 0.982 0.000
M06.14 Adult-onset Still's disease (Hand)
0.018 0.982 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.018 0.982 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.018 0.982 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.018 0.982 0.000
D13.6 Pancreas
0.018 0.982 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.018 0.982 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.000 0.982 0.018
K55 Vascular disorders of intestine
0.018 0.982 0.000
O40 Polyhydramnios
0.000 0.982 0.018
O41 Other disorders of amniotic fluid and membranes
0.000 0.982 0.018
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.018 0.982 0.000
O41.0 Oligohydramnios
0.000 0.982 0.018
D13.9 Ill-defined sites within the digestive system
0.017 0.983 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.017 0.983 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.017 0.983 0.000
O30.0 Twin pregnancy
0.000 0.983 0.017
O43.8 Other placental disorders
0.000 0.983 0.017
O43.9 Placental disorder, unspecified
0.000 0.983 0.017
M06.29 Rheumatoid bursitis (Site unspecified)
0.016 0.983 0.000
M06.28 Rheumatoid bursitis (Other)
0.016 0.983 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.016 0.983 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.016 0.983 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.016 0.983 0.000
M06.24 Rheumatoid bursitis (Hand)
0.016 0.983 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.016 0.983 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.016 0.983 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.016 0.983 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.016 0.983 0.000
O31 Complications specific to multiple gestation
0.000 0.983 0.017
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.016 0.983 0.000
K55.0 Acute vascular disorders of intestine
0.016 0.984 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.016 0.984 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.016 0.984 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.016 0.984 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.016 0.984 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.016 0.984 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.016 0.984 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.016 0.984 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.016 0.984 0.000
D13.2 Duodenum
0.016 0.984 0.000
D13.4 Liver
0.016 0.984 0.000
M06.4 Inflammatory polyarthropathy
0.016 0.984 0.000
O47.9 False labour, unspecified
0.000 0.984 0.016
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.000 0.984 0.016
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.015 0.984 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.984 0.016
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.016 0.984 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.000 0.984 0.016
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.000 0.984 0.015
F34 Persistent mood [affective] disorders
0.000 0.985 0.015
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.015 0.985 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.015 0.985 0.000
O45 Premature separation of placenta [abruptio placentae]
0.000 0.985 0.015
O30.1 Triplet pregnancy
0.000 0.985 0.015
D13.7 Endocrine pancreas
0.015 0.985 0.000
F38 Other mood [affective] disorders
0.000 0.985 0.015
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.985 0.015
O43.0 Placental transfusion syndromes
0.000 0.985 0.015
F30 Manic episode
0.000 0.985 0.015
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.985 0.014
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more
0.000 0.985 0.014
K55.1 Chronic vascular disorders of intestine
0.014 0.986 0.000
D13.0 Oesophagus
0.014 0.986 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.000 0.986 0.014
O43.1 Malformation of placenta
0.000 0.986 0.014
O43.2 Morbidly adherent placenta
0.000 0.986 0.014
F33.8 Other recurrent depressive disorders
0.000 0.986 0.014
O30.9 Multiple gestation, unspecified
0.000 0.986 0.013
O30.8 Other multiple gestation
0.000 0.986 0.013
O30.2 Quadruplet pregnancy
0.000 0.986 0.013
D13.3 Other and unspecified parts of small intestine
0.013 0.986 0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.000 0.987 0.013
O33 Maternal care for known or suspected disproportion
0.000 0.987 0.013
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.000 0.987 0.013
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.000 0.987 0.013
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.000 0.987 0.013
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.000 0.987 0.013
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.000 0.987 0.013
F30.2 Mania with psychotic symptoms
0.000 0.987 0.013
O34 Maternal care for known or suspected abnormality of pelvic organs
0.000 0.988 0.012
F34.1 Dysthymia
0.000 0.988 0.012
F39 Unspecified mood [affective] disorder
0.000 0.988 0.012
O42 Premature rupture of membranes
0.000 0.988 0.012
O31.1 Continuing pregnancy after abortion of one foetus or more
0.000 0.988 0.012
O31.0 Papyraceous foetus
0.000 0.988 0.012
M06.46 Inflammatory polyarthropathy (Lower leg)
0.012 0.988 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.012 0.988 0.000
O44 Placenta praevia
0.000 0.988 0.012
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.988 0.012
O41.1 Infection of amniotic sac and membranes
0.000 0.988 0.012
M06.48 Inflammatory polyarthropathy (Other)
0.011 0.988 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.011 0.988 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.011 0.988 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.011 0.988 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.011 0.988 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.011 0.988 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.011 0.988 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.000 0.988 0.012
O45.9 Premature separation of placenta, unspecified
0.000 0.988 0.011
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.000 0.989 0.011
O31.8 Other complications specific to multiple gestation
0.000 0.989 0.011
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.989 0.011
F34.8 Other persistent mood [affective] disorders
0.000 0.989 0.011
K55.8 Other vascular disorders of intestine
0.011 0.989 0.000
O45.8 Other premature separation of placenta
0.000 0.989 0.011
O45.0 Premature separation of placenta with coagulation defect
0.000 0.989 0.011
Z37.0 Single live birth
0.000 0.989 0.011
F34.0 Cyclothymia
0.000 0.989 0.011
F38.0 Other single mood [affective] disorders
0.000 0.989 0.011
F38.8 Other specified mood [affective] disorders
0.000 0.989 0.011
F38.1 Other recurrent mood [affective] disorders
0.000 0.989 0.011
F30.8 Other manic episodes
0.000 0.989 0.011
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.989 0.011
O34.4 Maternal care for other abnormalities of cervix
0.000 0.989 0.011
O42.2 Premature rupture of membranes, labour delayed by therapy
0.000 0.990 0.010
F30.0 Hypomania
0.000 0.990 0.010
F30.1 Mania without psychotic symptoms
0.000 0.990 0.010
K55.9 Vascular disorder of intestine, unspecified
0.010 0.990 0.000
O34.1 Maternal care for tumour of corpus uteri
0.000 0.990 0.010
O34.6 Maternal care for abnormality of vagina
0.000 0.990 0.010
O33.8 Maternal care for disproportion of other origin
0.000 0.990 0.010
O33.7 Maternal care for disproportion due to other foetal deformities
0.000 0.990 0.010
O33.6 Maternal care for disproportion due to hydrocephalic foetus
0.000 0.990 0.010
O33.4 Maternal care for disproportion of mixed maternal and foetal origin
0.000 0.990 0.010
O33.3 Maternal care for disproportion due to outlet contraction of pelvis
0.000 0.990 0.010
O33.2 Maternal care for disproportion due to inlet contraction of pelvis
0.000 0.990 0.010
O33.1 Maternal care for disproportion due to generally contracted pelvis
0.000 0.990 0.010
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones
0.000 0.990 0.010
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.010 0.990 0.000
O33.5 Maternal care for disproportion due to unusually large foetus
0.000 0.990 0.010
O41.8 Other specified disorders of amniotic fluid and membranes
0.000 0.990 0.010
O34.2 Maternal care due to uterine scar from previous surgery
0.000 0.990 0.010
H33.0 Retinal detachment with retinal break
0.000 0.990 0.010
Z01.6 Radiological examination, not elsewhere classified
0.000 0.990 0.009
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.000 0.991 0.009
O34.5 Maternal care for other abnormalities of gravid uterus
0.000 0.991 0.009
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.009 0.991 0.000
O34.0 Maternal care for congenital malformation of uterus
0.000 0.991 0.009
O33.9 Maternal care for disproportion, unspecified
0.000 0.991 0.008
N41.0 Acute prostatitis
0.009 0.991 0.000
F30.9 Manic episode, unspecified
0.000 0.992 0.008
H33.2 Serous retinal detachment
0.000 0.992 0.008
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.000 0.992 0.008
O34.8 Maternal care for other abnormalities of pelvic organs
0.000 0.992 0.008
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.007 0.992 0.001
O44.1 Placenta praevia with haemorrhage
0.000 0.992 0.008
O42.9 Premature rupture of membranes, unspecified
0.000 0.992 0.008
O44.0 Placenta praevia specified as without haemorrhage
0.000 0.992 0.007
O46 Antepartum haemorrhage, not elsewhere classified
0.001 0.993 0.007
C84 Peripheral and cutaneous T-cell lymphomas
0.007 0.993 0.000
O34.3 Maternal care for cervical incompetence
0.000 0.993 0.007
O32 Maternal care for known or suspected malpresentation of foetus
0.000 0.993 0.007
H33 Retinal detachments and breaks
0.000 0.993 0.007
C92 Myeloid leukaemia
0.007 0.993 0.000
C86 Other specified types of T/NK-cell lymphoma
0.007 0.993 0.000
C84.4 Peripheral T-cell lymphoma
0.007 0.993 0.000
C91 Lymphoid leukaemia
0.007 0.993 0.000
C92.0 Acute myeloid leukaemia
0.007 0.993 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.006 0.993 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.006 0.994 0.000
C93 Monocytic leukaemia
0.006 0.994 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.006 0.994 0.000
O32.6 Maternal care for compound presentation
0.000 0.994 0.006
C92.7 Other myeloid leukaemia
0.006 0.994 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.006 0.994 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.006 0.994 0.000
C91.4 Hairy-cell leukaemia
0.006 0.994 0.000
L53.9 Erythematous condition, unspecified
0.006 0.994 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.006 0.994 0.000
C95 Leukaemia of unspecified cell type
0.006 0.994 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.006 0.994 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.000 0.994 0.006
C84.0 Mycosis fungoides
0.006 0.994 0.000
O32.3 Maternal care for face, brow and chin presentation
0.000 0.994 0.006
O46.0 Antepartum haemorrhage with coagulation defect
0.001 0.994 0.005
O32.2 Maternal care for transverse and oblique lie
0.000 0.994 0.006
C84.9 Mature T/NK-cell lymphoma, unspecified
0.005 0.994 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.005 0.994 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.005 0.994 0.000
C84.3 Lymphoepithelioid lymphoma
0.005 0.994 0.000
C84.2 T-zone lymphoma
0.005 0.994 0.000
C84.1 Sezary's diease
0.005 0.994 0.000
C94 Other leukaemias of specified cell type
0.005 0.994 0.000
C90.2 Plasmacytoma, extramedullary
0.006 0.994 0.000
C82.2 Large cell, follicular
0.005 0.994 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.005 0.995 0.000
H33.5 Other retinal detachments
0.000 0.995 0.005
C92.9 Myeloid leukaemia, unspecified
0.005 0.995 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.000 0.995 0.005
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.005 0.995 0.000
C91.5 Adult T-cell leukaemia
0.005 0.995 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.005 0.995 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.005 0.995 0.000
C92.3 Myeloid sarcoma
0.005 0.995 0.000
C91.9 Lymphoid leukaemia, unspecified
0.005 0.995 0.000
H33.1 Retinoschisis and retinal cysts
0.000 0.995 0.005
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.005 0.995 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.005 0.995 0.000
C86.4 Blastic NK-cell lymphoma
0.005 0.995 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.005 0.995 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.005 0.995 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.005 0.995 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.005 0.995 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.005 0.995 0.000
C92.5 Acute myelomonocytic leukaemia
0.005 0.995 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.005 0.995 0.000
C91.7 Other lymphoid leukaemia
0.005 0.995 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.005 0.995 0.000
C91.3 Prolymphocytic leukaemia
0.005 0.995 0.000
C91.2 Subacute lymphocytic leukaemia
0.005 0.995 0.000
O32.0 Maternal care for unstable lie
0.000 0.995 0.005
C82.0 Small cleaved cell, follicular
0.005 0.995 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.000 0.995 0.005
C88 Malignant immunoproliferative diseases
0.005 0.995 0.000
H26.4 After-cataract
0.000 0.995 0.005
C92.2 Subacute myeloid leukaemia
0.005 0.995 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.005 0.995 0.000
C96.8 Histiocytic sarcoma
0.005 0.995 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.005 0.995 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.005 0.995 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.005 0.995 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.005 0.995 0.000
C96.3 True histiocytic lymphoma
0.005 0.995 0.000
C96.2 Malignant mast cell tumour
0.005 0.995 0.000
C96.1 Malignant histiocytosis
0.005 0.995 0.000
C96.0 Letterer-Siwe disease
0.005 0.995 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.005 0.995 0.000
C82.6 Cutaneous follicle centre lymphoma
0.005 0.995 0.000
C82.5 Diffuse follicle centre lymphoma
0.005 0.995 0.000
C93.9 Monocytic leukaemia, unspecified
0.005 0.995 0.000
C93.7 Other monocytic leukaemia
0.005 0.995 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.005 0.995 0.000
C93.2 Subacute monocytic leukaemia
0.005 0.995 0.000
C93.0 Acute monocytic leukaemia
0.005 0.995 0.000
C84.5 Other and unspecified T-cell lymphomas
0.005 0.995 0.000
O32.4 Maternal care for high head at term
0.000 0.995 0.005
L29.0 Pruritus ani
0.000 0.995 0.005
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.005 0.995 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.005 0.995 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.000 0.995 0.005
O46.8 Other antepartum haemorrhage
0.001 0.995 0.004
C95.1 Chronic leukaemia of unspecified cell type
0.004 0.995 0.000
C85.0 Lymphosarcoma
0.004 0.995 0.000
O36 Maternal care for other known or suspected foetal problems
0.000 0.995 0.005
C90.3 Solitary plasmacytoma
0.004 0.995 0.000
C82.3 Follicular lymphoma grade IIIa
0.004 0.995 0.000
C91.0 Acute lymphoblastic leukaemia
0.004 0.995 0.000
C93.1 Chronic monocytic leukaemia
0.004 0.995 0.000
O32.8 Maternal care for other malpresentation of foetus
0.000 0.995 0.004
O36.3 Maternal care for signs of foetal hypoxia
0.000 0.995 0.005
C95.7 Other leukaemia of unspecified cell type
0.004 0.996 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.004 0.996 0.000
C94.7 Other specified leukaemias
0.004 0.996 0.000
C94.5 Acute myelofibrosis
0.004 0.996 0.000
C94.3 Mast cell leukaemia
0.004 0.996 0.000
C94.2 Acute megakaryoblastic leukaemia
0.004 0.996 0.000
C94.1 Chronic erythraemia
0.004 0.996 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.004 0.996 0.000
H33.3 Retinal breaks without detachment
0.000 0.996 0.004
J03.9 Acute tonsillitis, unspecified
0.000 0.996 0.004
K58.0 Irritable bowel syndrome with diarrhoea
0.004 0.996 0.000
C95.0 Acute leukaemia of unspecified cell type
0.004 0.996 0.000
C90.1 Plasma cell leukaemia
0.004 0.996 0.000
H33.4 Traction detachment of retina
0.000 0.996 0.004
C94.4 Acute panmyelosis
0.004 0.996 0.000
I20.8 Other forms of angina pectoris
0.004 0.996 0.000
C82.4 Follicular lymphoma grade IIIb
0.004 0.996 0.000
U88 Agent resistant to multiple antibiotics
0.000 0.996 0.004
M85.8 Other specified disorders of bone density and structure
0.004 0.996 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.004 0.996 0.000
C88.7 Other malignant immunoproliferative diseases
0.004 0.996 0.000
C88.3 Immunoproliferative small intestinal disease
0.004 0.996 0.000
C88.2 Gamma heavy chain disease
0.004 0.996 0.000
C88.1 Alpha heavy chain disease
0.004 0.996 0.000
C92.4 Acute promyelocytic leukaemia
0.004 0.996 0.000
D48.0 Bone and articular cartilage
0.000 0.996 0.004
O36.1 Maternal care for other isoimmunisation
0.000 0.996 0.004
C91.1 Chronic lymphocytic leukaemia
0.004 0.996 0.000
C95.9 Leukaemia, unspecified
0.004 0.996 0.000
Z37 Outcome of delivery
0.000 0.996 0.004
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.003 0.996 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.003 0.996 0.000
M05-M14 Inflammatory polyarthropathies
0.004 0.996 0.000
O36.2 Maternal care for hydrops foetalis
0.000 0.996 0.003
C92.1 Chronic myeloid leukaemia
0.003 0.997 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.000 0.997 0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.003 0.997 0.000
M14 Arthropathies in other diseases classified elsewhere
0.003 0.997 0.000
O36.9 Maternal care for foetal problem, unspecified
0.000 0.997 0.003
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.003 0.997 0.000
M85.6 Other cyst of bone
0.003 0.997 0.000
C50.2 Upper-inner quadrant of breast
0.000 0.997 0.003
R90.0 Intracranial space-occupying lesion
0.003 0.997 0.000
Z37.5 Other multiple births, all liveborn
0.000 0.997 0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.003 0.997 0.000
K22.2 Oesophageal obstruction
0.000 0.997 0.003
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.003 0.997 0.000
M14.6 Neuropathic arthropathy
0.003 0.997 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.003 0.997 0.000
M85.68 Other cyst of bone (Other)
0.003 0.997 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.003 0.997 0.000
L85.9 Epidermal thickening, unspecified
0.003 0.997 0.000
M85 Other disorders of bone density and structure
0.003 0.997 0.000
C81 Hodgkin's disease
0.003 0.997 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.003 0.997 0.000
M85.64 Other cyst of bone (Hand)
0.003 0.997 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.003 0.997 0.000
Z37.3 Twins, one liveborn and one stillborn
0.000 0.997 0.003
Y51 Drugs primarily affecting the autonomic nervous system
0.003 0.997 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.003 0.997 0.000
Z37.9 Outcome of delivery unspecified
0.000 0.997 0.003
Z37.7 Other multiple births, all stillborn
0.000 0.997 0.003
Z37.6 Other multiple births, some liveborn
0.000 0.997 0.003
Z37.4 Twins, both stillborn
0.000 0.997 0.003
Z37.2 Twins, both liveborn
0.000 0.997 0.003
M85.4 Solitary bone cyst
0.003 0.997 0.000
O36.5 Maternal care for poor foetal growth
0.000 0.997 0.003
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.003 0.997 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.003 0.997 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.003 0.997 0.000
G12.2 Motor neuron disease
0.003 0.997 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.003 0.997 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.003 0.997 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.003 0.997 0.000
C85.1 B-cell lymphoma, unspecified
0.003 0.997 0.000
M12 Other specific arthropathies
0.003 0.997 0.000
M85.66 Other cyst of bone (Lower leg)
0.003 0.997 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.003 0.997 0.000
M14.4 Arthropathy in amyloidosis
0.003 0.997 0.000
M14.3 Lipoid dermatoarthritis
0.003 0.997 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.003 0.997 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.003 0.997 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.002 0.997 0.000
M14.2 Diabetic arthropathy
0.003 0.997 0.000
L53 Other erythematous conditions
0.003 0.997 0.000
M08 Juvenile arthritis
0.002 0.997 0.000
M05 Seropositive rheumatoid arthritis
0.003 0.997 0.000
M85.69 Other cyst of bone (Site unspecified)
0.003 0.997 0.000
M85.63 Other cyst of bone (Forearm)
0.003 0.997 0.000
M85.62 Other cyst of bone (Upper arm)
0.003 0.997 0.000
M85.61 Other cyst of bone (Shoulder region)
0.003 0.997 0.000
M85.60 Other cyst of bone (Multiple sites)
0.003 0.997 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.002 0.997 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.003 0.997 0.000
M85.2 Hyperostosis of skull
0.002 0.997 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.002 0.997 0.000
M11 Other crystal arthropathies
0.003 0.997 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.002 0.997 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.002 0.997 0.000
Q43.0 Meckel's diverticulum
0.003 0.997 0.000
M85.5 Aneurysmal bone cyst
0.002 0.997 0.000
M85.3 Osteitis condensans
0.002 0.997 0.000
M85.1 Skeletal fluorosis
0.002 0.997 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.002 0.997 0.000
C81.3 Lymphocytic depletion
0.002 0.997 0.000
O36.4 Maternal care for intra-uterine death
0.000 0.998 0.002
C81.7 Other Hodgkin's disease
0.002 0.998 0.000
N04.9 Unspecified
0.002 0.998 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.002 0.998 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.002 0.998 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.002 0.998 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.002 0.998 0.000
Y51.0 Anticholinesterase agents
0.002 0.998 0.000
O36.8 Maternal care for other specified foetal problems
0.000 0.998 0.002
M85.49 Solitary bone cyst (Site unspecified)
0.002 0.998 0.000
M85.48 Solitary bone cyst (Other)
0.002 0.998 0.000
M85.44 Solitary bone cyst (Hand)
0.002 0.998 0.000
M85.43 Solitary bone cyst (Forearm)
0.002 0.998 0.000
M85.42 Solitary bone cyst (Upper arm)
0.002 0.998 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.002 0.998 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.002 0.998 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.002 0.998 0.000
O32.1 Maternal care for breech presentation
0.000 0.998 0.002
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.998 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.998 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.998 0.000
M09.0 Juvenile arthritis in psoriasis
0.002 0.998 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.002 0.998 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.002 0.998 0.000
M12.2 Villonodular synovitis (pigmented)
0.002 0.998 0.000
M05.8 Other seropositive rheumatoid arthritis
0.002 0.998 0.000
M85.9 Disorder of bone density and structure, unspecified
0.002 0.998 0.000
M85.0 Fibrous dysplasia (monostotic)
0.002 0.998 0.000
M85.46 Solitary bone cyst (Lower leg)
0.002 0.998 0.000
M12.4 Intermittent hydrarthrosis
0.002 0.998 0.000
M12.1 Kaschin-Beck disease
0.002 0.998 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.998 0.000
C81.1 Nodular sclerosis
0.002 0.998 0.000
M05.1 Rheumatoid lung disease
0.002 0.998 0.000
L53.0 Toxic erythema
0.002 0.998 0.000
M12.5 Traumatic arthropathy
0.002 0.998 0.000
L29.8 Other pruritus
0.000 0.998 0.002
L53.3 Other chronic figurate erythema
0.002 0.998 0.000
L53.2 Erythema marginatum
0.002 0.998 0.000
L53.1 Erythema annulare centrifugum
0.002 0.998 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.998 0.000
M05.0 Felty's syndrome
0.002 0.998 0.000
M08.9 Juvenile arthritis, unspecified
0.002 0.998 0.000
M08.8 Other juvenile arthritis
0.002 0.998 0.000
M08.4 Pauciarticular juvenile arthritis
0.002 0.998 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.998 0.000
M08.2 Juvenile arthritis with systemic onset
0.002 0.998 0.000
M08.1 Juvenile ankylosing spondylitis
0.002 0.998 0.000
M85.20 Hyperostosis of skull-Mult sites
0.002 0.998 0.000
K02.9 Dental caries, unspecified
0.002 0.998 0.000
C81.0 Lymphocytic predominance
0.002 0.998 0.000
M85.22 Hyperostosis of skull-Upper arm
0.002 0.998 0.000
M85.29 Hyperostosis of skull-Site unspec
0.002 0.998 0.000
M85.28 Hyperostosis of skull-Other
0.002 0.998 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.002 0.998 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.002 0.998 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.002 0.998 0.000
M85.24 Hyperostosis of skull-Hand
0.002 0.998 0.000
M85.23 Hyperostosis of skull-Forearm
0.002 0.998 0.000
M85.21 Hyperostosis of skull-Shldr region
0.002 0.998 0.000
M05.2 Rheumatoid vasculitis
0.002 0.998 0.000
O14.0 Moderate preeclampsia
0.000 0.998 0.002
M07 Psoriatic and enteropathic arthropathies
0.002 0.998 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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