TreeWAS – Variant ID: rs4820268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	0.000	0.003	0.997
D64 Other anaemias	0.000	0.221	0.779
D60-D64 Aplastic and other anaemias	0.000	0.298	0.702
D62 Acute posthaemorrhagic anaemia	0.000	0.301	0.699
D64.4 Congenital dyserythropoietic anaemia	0.000	0.441	0.559
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.441	0.559
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.441	0.559
D64.0 Hereditary sideroblastic anaemia	0.000	0.459	0.541
D64.3 Other sideroblastic anaemias	0.000	0.482	0.518
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.520	0.480
D64.8 Other specified anaemias	0.000	0.566	0.434
D61 Other aplastic anaemias	0.000	0.585	0.415
D60.8 Other acquired pure red cell aplasias	0.000	0.656	0.344
D60.1 Transient acquired pure red cell aplasia	0.000	0.656	0.344
D60.0 Chronic acquired pure red cell aplasia	0.000	0.656	0.344
D61.1 Drug-induced aplastic anaemia	0.000	0.662	0.338
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.679	0.321
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.702	0.298
D61.8 Other specified aplastic anaemias	0.000	0.702	0.298
D61.3 Idiopathic aplastic anaemia	0.000	0.702	0.298
D61.2 Aplastic anaemia due to other external agents	0.000	0.702	0.298
D61.0 Constitutional aplastic anaemia	0.000	0.719	0.280
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.786	0.214
E83.1 Disorders of iron metabolism	0.181	0.819	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.853	0.147
D61.9 Aplastic anaemia, unspecified	0.000	0.856	0.143
D63.0 Anaemia in neoplastic disease	0.000	0.863	0.137
R07.4 Chest pain, unspecified	0.000	0.917	0.083
E83 Disorders of mineral metabolism	0.052	0.948	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.950	0.050
D55-D59 Haemolytic anaemias	0.000	0.953	0.047
E83.4 Disorders of magnesium metabolism	0.043	0.957	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.041	0.959	0.000
D58 Other hereditary haemolytic anaemias	0.000	0.960	0.040
D59 Acquired haemolytic anaemia	0.000	0.961	0.039
E83.8 Other disorders of mineral metabolism	0.038	0.962	0.000
E83.2 Disorders of zinc metabolism	0.038	0.962	0.000
E83.0 Disorders of copper metabolism	0.038	0.962	0.000
D57 Sickle-cell disorders	0.000	0.963	0.037
D59.1 Other autoimmune haemolytic anaemias	0.000	0.964	0.036
D56 Thalassaemia	0.000	0.964	0.036
D58.0 Hereditary spherocytosis	0.000	0.965	0.035
D55 Anaemia due to enzyme disorders	0.000	0.966	0.034
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.967	0.033
D57.1 Sickle-cell anaemia without crisis	0.000	0.970	0.030
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.971	0.029
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.971	0.029
D58.1 Hereditary elliptocytosis	0.000	0.971	0.029
D59.8 Other acquired haemolytic anaemias	0.000	0.972	0.028
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.972	0.028
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.972	0.028
D59.3 Haemolytic-uraemic syndrome	0.000	0.972	0.028
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.972	0.028
D56.1 Beta thalassaemia	0.000	0.973	0.027
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.973	0.027
D57.8 Other sickle-cell disorders	0.000	0.973	0.027
D57.3 Sickle-cell trait	0.000	0.973	0.027
D57.2 Double heterozygous sickling disorders	0.000	0.973	0.027
D57.0 Sickle-cell anaemia with crisis	0.000	0.973	0.027
E83.5 Disorders of calcium metabolism	0.027	0.973	0.000
D56.3 Thalassaemia trait	0.000	0.974	0.026
D50-D53 Nutritional anaemias	0.000	0.974	0.026
D56.9 Thalassaemia, unspecified	0.000	0.974	0.026
D56.8 Other thalassaemias	0.000	0.974	0.026
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.974	0.026
D56.2 Delta-beta thalassaemia	0.000	0.974	0.026
D56.0 Alpha thalassaemia	0.000	0.974	0.026
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.976	0.024
D55.8 Other anaemias due to enzyme disorders	0.000	0.976	0.024
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.976	0.024
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.976	0.024
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.976	0.024
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.976	0.024
D58.2 Other haemoglobinopathies	0.000	0.977	0.023
E83.3 Disorders of phosphorus metabolism	0.020	0.980	0.000
D53 Other nutritional anaemias	0.000	0.980	0.020
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.980	0.020
D80-D89 Certain disorders involving the immune mechanism	0.000	0.980	0.020
D12.0 Caecum	0.019	0.981	0.000
Z96.8 Presence of other specified functional implants	0.000	0.983	0.017
D50 Iron deficiency anaemia	0.000	0.983	0.017
D50.8 Other iron deficiency anaemias	0.000	0.983	0.017
D53.9 Nutritional anaemia, unspecified	0.000	0.984	0.016
D51 Vitamin B12 deficiency anaemia	0.000	0.984	0.016
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.985	0.015
D53.8 Other specified nutritional anaemias	0.000	0.985	0.015
D53.2 Scorbutic anaemia	0.000	0.985	0.015
D53.0 Protein deficiency anaemia	0.000	0.985	0.015
D82 Immunodeficiency associated with other major defects	0.000	0.985	0.015
D81 Combined immunodeficiencies	0.000	0.985	0.014
D12.7 Rectosigmoid junction	0.014	0.986	0.000
D52 Folate deficiency anaemia	0.000	0.986	0.014
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.986	0.014
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.014	0.986	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.986	0.013
D86 Sarcoidosis	0.000	0.987	0.013
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.988	0.012
D50.1 Sideropenic dysphagia	0.000	0.988	0.012
D12.3 Transverse colon	0.012	0.988	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.988	0.012
D89.1 Cryoglobulinaemia	0.000	0.988	0.012
D12.2 Ascending colon	0.012	0.988	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.988	0.012
D51.2 Transcobalamin II deficiency	0.000	0.988	0.012
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.988	0.012
D86.3 Sarcoidosis of skin	0.000	0.988	0.012
D83 Common variable immunodeficiency	0.000	0.988	0.011
D84 Other immunodeficiencies	0.000	0.989	0.011
D82.1 Di George's syndrome	0.000	0.989	0.011
D12.1 Appendix	0.011	0.989	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.989	0.011
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.989	0.011
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.989	0.011
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.989	0.011
D82.2 Immunodeficiency with short-limbed stature	0.000	0.989	0.011
D82.0 Wiskott-Aldrich syndrome	0.000	0.989	0.011
D81.9 Combined immunodeficiency, unspecified	0.000	0.989	0.010
D81.8 Other combined immunodeficiencies	0.000	0.989	0.010
D81.7 Major histocompatibility complex class II deficiency	0.000	0.989	0.010
D81.6 Major histocompatibility complex class I deficiency	0.000	0.989	0.010
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.989	0.010
D81.4 Nezelof's syndrome	0.000	0.989	0.010
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.989	0.010
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.989	0.010
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.989	0.010
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.989	0.010
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.989	0.011
N75.0 Cyst of Bartholin's gland	0.000	0.989	0.011
D52.8 Other folate deficiency anaemias	0.000	0.989	0.010
D52.1 Drug-induced folate deficiency anaemia	0.000	0.989	0.010
D52.0 Dietary folate deficiency anaemia	0.000	0.989	0.010
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.990	0.010
D12.4 Descending colon	0.010	0.990	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.990	0.010
D86.1 Sarcoidosis of lymph nodes	0.000	0.990	0.010
D89.3 Immune reconstitution syndrome	0.000	0.990	0.010
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.990	0.010
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.990	0.010
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.990	0.010
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.990	0.010
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.990	0.010
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.990	0.010
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.990	0.010
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.990	0.010
E80.4 Gilbert's syndrome	0.010	0.990	0.000
E16.2 Hypoglycaemia, unspecified	0.010	0.990	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.990	0.009
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.990	0.009
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.990	0.010
C56 Malignant neoplasm of ovary	0.010	0.990	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.990	0.009
D12.5 Sigmoid colon	0.009	0.991	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.991	0.009
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.991	0.009
D83.8 Other common variable immunodeficiencies	0.000	0.991	0.008
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.991	0.008
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.991	0.008
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.991	0.008
D84.8 Other specified immunodeficiencies	0.000	0.991	0.008
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.992	0.008
D12.9 Anus and anal canal	0.008	0.992	0.000
D12.8 Rectum	0.008	0.992	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.008	0.992	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.993	0.007
D84.1 Defects in the complement system	0.000	0.993	0.007
D84.9 Immunodeficiency, unspecified	0.000	0.993	0.007
E16 Other disorders of pancreatic internal secretion	0.006	0.993	0.000
E80.1 Porphyria cutanea tarda	0.006	0.994	0.000
O42 Premature rupture of membranes	0.000	0.994	0.006
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.994	0.006
E70-E90 Metabolic disorders	0.006	0.994	0.000
E80.2 Other porphyria	0.006	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.994	0.006
D83.9 Common variable immunodeficiency, unspecified	0.001	0.994	0.005
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.994	0.006
D52.9 Folate deficiency anaemia, unspecified	0.000	0.994	0.006
E80.7 Disorder of bilirubin metabolism, unspecified	0.006	0.994	0.000
E80.5 Crigler-Najjar syndrome	0.006	0.994	0.000
E80.3 Defects of catalase and peroxydase	0.006	0.994	0.000
E80.0 Hereditary erythropoietic porphyria	0.006	0.994	0.000
L03.3 Cellulitis of trunk	0.005	0.995	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.995	0.005
M17.3 Other posttraumatic gonarthrosis	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.000	0.995	0.005
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.995	0.005
S00.1 Contusion of eyelid and periocular area	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.005	0.995	0.000
E84 Cystic fibrosis	0.005	0.995	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.000	0.995	0.005
Z32.1 Pregnancy confirmed	0.000	0.995	0.005
E72 Other disorders of amino-acid metabolism	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.005	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.005	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.005	0.995	0.000
E16.3 Increased secretion of glucagon	0.005	0.995	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.995	0.005
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.005	0.995	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.995	0.005
E73 Lactose intolerance	0.005	0.995	0.000
E74 Other disorders of carbohydrate metabolism	0.005	0.995	0.000
M34.1 CR(E)ST syndrome	0.000	0.995	0.005
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.995	0.005
D86.0 Sarcoidosis of lung	0.000	0.995	0.004
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.004	0.995	0.000
E77 Disorders of glycoprotein metabolism	0.004	0.995	0.000
E76 Disorders of glycosaminoglycan metabolism	0.004	0.995	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.004	0.995	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.004	0.995	0.000
E80.6 Other disorders of bilirubin metabolism	0.004	0.996	0.000
Z01.6 Radiological examination, not elsewhere classified	0.004	0.996	0.000
E72.0 Disorders of amino-acid transport	0.004	0.996	0.000
E70.3 Albinism	0.004	0.996	0.000
E79 Disorders of purine and pyrimidine metabolism	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.996	0.004
D74 Methaemoglobinaemia	0.000	0.996	0.004
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.996	0.004
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.996	0.004
E84.9 Cystic fibrosis, unspecified	0.004	0.996	0.000
E85 Amyloidosis	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.000	0.996	0.004
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.004	0.996	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.996	0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.996	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E75.5 Other lipid storage disorders	0.004	0.996	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.996	0.004
R52.1 Chronic intractable pain	0.000	0.996	0.004
K74.3 Primary biliary cirrhosis	0.000	0.996	0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.003	0.996	0.000
E73.1 Secondary lactase deficiency	0.003	0.996	0.000
E73.0 Congenital lactase deficiency	0.003	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.003	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.003	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.003	0.996	0.000
E74.2 Disorders of galactose metabolism	0.003	0.996	0.000
E74.1 Disorders of fructose metabolism	0.003	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.996	0.003
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.996	0.004
E75.6 Lipid storage disorder, unspecified	0.003	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.003	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.003	0.996	0.000
E75.1 Other gangliosidosis	0.003	0.996	0.000
E75.0 GM2 gangliosidosis	0.003	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.003	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.003	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.003	0.996	0.000
E71.0 Maple-syrup-urine disease	0.003	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.003	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.003	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.003	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.003	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.003	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.003	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.003	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.003	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.003	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.003	0.996	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.004	0.996	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.003	0.997	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.003	0.997	0.000
E79.1 Lesch-Nyhan syndrome	0.003	0.997	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.000	0.997	0.003
E74.0 Glycogen storage disease	0.003	0.997	0.000
M62.84 Other specified disorders of muscle (Hand)	0.000	0.997	0.003
D74.9 Methaemoglobinaemia, unspecified	0.000	0.997	0.003
D74.8 Other methaemoglobinaemias	0.000	0.997	0.003
D74.0 Congenital methaemoglobinaemia	0.000	0.997	0.003
E75.2 Other sphingolipidosis	0.003	0.997	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.997	0.003
E85.8 Other amyloidosis	0.003	0.997	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.003	0.997	0.000
I84.0 Internal thrombosed haemorrhoids	0.000	0.997	0.003
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
E85.2 Heredofamilial amyloidosis, unspecified	0.003	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.003	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.003	0.997	0.000
N75 Diseases of Bartholin's gland	0.000	0.997	0.003
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.997	0.003
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.997	0.003
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.997	0.003
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.997	0.003
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.000	0.997	0.003
K82.4 Cholesterolosis of gallbladder	0.000	0.997	0.003
D75 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.997	0.003
D69.9 Haemorrhagic condition, unspecified	0.000	0.997	0.003
D73 Diseases of spleen	0.000	0.997	0.003
D72 Other disorders of white blood cells	0.000	0.997	0.003
Q21.0 Ventricular septal defect	0.003	0.997	0.000
M34 Systemic sclerosis	0.000	0.997	0.003
I45.5 Other specified heart block	0.003	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
K56.5 Intestinal adhesions [bands] with obstruction	0.003	0.997	0.000
D73.3 Abscess of spleen	0.000	0.997	0.003
D76.3 Other histiocytosis syndromes	0.000	0.997	0.003
U51 Admission status on psychiatric patients	0.000	0.997	0.003
D12.6 Colon, unspecified	0.003	0.997	0.000
Z45.8 Adjustment and management of other implanted devices	0.003	0.997	0.000
M70.22 Olecranon bursitis-Upper arm	0.003	0.997	0.000
N75.8 Other diseases of Bartholin's gland	0.000	0.997	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.997	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.997	0.000
R58 Haemorrhage, not elsewhere classified	0.003	0.997	0.000
N30.0 Acute cystitis	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.998	0.002
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.998	0.002
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.002
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.002
D72.9 Disorder of white blood cells, unspecified	0.000	0.998	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.998	0.002
D73.2 Chronic congestive splenomegaly	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.002
D72.1 Eosinophilia	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
D73.4 Cyst of spleen	0.000	0.998	0.002
E88 Other metabolic disorders	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.998	0.002
D73.9 Disease of spleen, unspecified	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
E87.6 Hypokalaemia	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
D73.1 Hypersplenism	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.002	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
D68 Other coagulation defects	0.000	0.998	0.002
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
U50 Level of care administered to neonates	0.000	0.998	0.002
U07 Emergency use of U07	0.000	0.998	0.002
U06 Emergency use of U06	0.000	0.998	0.002
U04 Severe acute respiratory syndrome [SARS]	0.000	0.998	0.002
U52 First in a series of a regular day/night admissions	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
D69.0 Allergic purpura	0.000	0.998	0.002
I73.0 Raynaud's syndrome	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
D73.5 Infarction of spleen	0.000	0.998	0.002
E88.8 Other specified metabolic disorders	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
U80.1 Methicillin resistant agent	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
M62 Other disorders of muscle	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.002
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
K08.3 Retained dental root	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.001	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.998	0.002
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Z32 Pregnancy examination and test	0.000	0.998	0.002
D50.9 Iron deficiency anaemia, unspecified	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.998	0.001
U06.9 Emergency use of U06.9	0.000	0.998	0.001
U06.8 Emergency use of U06.8	0.000	0.998	0.001
U06.7 Emergency use of U06.7	0.000	0.998	0.001
U06.6 Emergency use of U06.6	0.000	0.998	0.001
U06.5 Emergency use of U06.5	0.000	0.998	0.001
U06.4 Emergency use of U06.4	0.000	0.998	0.001
U06.3 Emergency use of U06.3	0.000	0.998	0.001
U06.2 Emergency use of U06.2	0.000	0.998	0.001
U06.1 Emergency use of U06.1	0.000	0.998	0.001
U06.0 Emergency use of U06.0	0.000	0.998	0.001
U07.9 Emergency use of U07.9	0.000	0.998	0.001
U07.8 Emergency use of U07.8	0.000	0.998	0.001
U07.7 Emergency use of U07.7	0.000	0.998	0.001
U07.6 Emergency use of U07.6	0.000	0.998	0.001
U07.5 Emergency use of U07.5	0.000	0.998	0.001
U07.4 Emergency use of U07.4	0.000	0.998	0.001
U07.3 Emergency use of U07.3	0.000	0.998	0.001
U07.2 Emergency use of U07.2	0.000	0.998	0.001
U07.1 Emergency use of U07.1	0.000	0.998	0.001
U07.0 Emergency use of U07.0	0.000	0.998	0.001
U50.9 Inquest Adjourned Death	0.000	0.998	0.001
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.998	0.001
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.998	0.001
U50.1 Level of care administered to neonates (Special Care)	0.000	0.998	0.001
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.998	0.001
Q26 Congenital malformations of great veins	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.998	0.002
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.998	0.000
E89.4 Postprocedural ovarian failure	0.001	0.998	0.000
M62.9 Disorder of muscle, unspecified	0.000	0.998	0.001
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
R52.0 Acute pain	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.001
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
O86.1 Other infection of genital tract following delivery	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
O86 Other puerperal infections	0.000	0.998	0.002
E88.3 Tumour lysis syndrome	0.001	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
O86.8 Other specified puerperal infections	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
Q22.1 Congenital pulmonary valve stenosis	0.001	0.998	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
M62.4 Contracture of muscle	0.000	0.998	0.001
M62.3 Immobility syndrome (paraplegic)	0.000	0.998	0.001
M62.2 Ischaemic infarction of muscle	0.000	0.998	0.001
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.001	0.998	0.000
C53.1 Exocervix	0.001	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations