TreeWAS – Variant ID: rs4846478

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.940	0.060
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.941	0.059
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.943	0.057
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.945	0.055
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.946	0.054
T39.1 4-Aminophenol derivatives	0.000	0.947	0.053
T40.2 Other opioids	0.000	0.947	0.053
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.948	0.052
C78.0 Secondary malignant neoplasm of lung	0.051	0.949	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.949	0.050
C78.7 Secondary malignant neoplasm of liver	0.050	0.950	0.000
T43.2 Other and unspecified antidepressants	0.000	0.951	0.049
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.951	0.049
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.048	0.952	0.000
T40.6 Other and unspecified narcotics	0.000	0.952	0.048
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.954	0.046
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.955	0.045
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.955	0.045
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.955	0.045
T43.6 Psychostimulants with abuse potential	0.000	0.956	0.044
C78.1 Secondary malignant neoplasm of mediastinum	0.043	0.957	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.957	0.043
T39.4 Antirheumatics, not elsewhere classified	0.000	0.957	0.043
T39.2 Pyrazolone derivatives	0.000	0.957	0.043
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.957	0.043
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.959	0.041
C78.4 Secondary malignant neoplasm of small intestine	0.040	0.960	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.960	0.040
T40.8 Lysergide [LSD]	0.000	0.960	0.040
T40.7 Cannabis (derivatives)	0.000	0.960	0.040
T40.3 Methadone	0.000	0.960	0.040
T40.1 Heroin	0.000	0.960	0.040
T40.0 Opium	0.000	0.960	0.040
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.960	0.040
T36 Poisoning by systemic antibiotics	0.000	0.961	0.039
T43.9 Psychotropic drug, unspecified	0.000	0.961	0.039
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.961	0.039
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.961	0.039
T40.5 Cocaine	0.000	0.962	0.038
T39.0 Salicylates	0.000	0.962	0.038
T40.4 Other synthetic narcotics	0.000	0.962	0.038
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.962	0.038
T50.8 Diagnostic agents	0.000	0.963	0.037
T50.7 Analeptics and opioid receptor antagonists	0.000	0.963	0.037
T50.5 Appetite depressants	0.000	0.963	0.037
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.963	0.037
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.963	0.037
T50.1 Loop [high-ceiling] diuretics	0.000	0.963	0.037
T50.0 Mineralocorticoids and their antagonists	0.000	0.963	0.037
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.963	0.037
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.963	0.037
T42.4 Benzodiazepines	0.000	0.964	0.036
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.964	0.036
T50.4 Drugs affecting uric acid metabolism	0.000	0.964	0.036
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.965	0.035
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.035	0.965	0.000
T42.0 Hydantoin derivatives	0.000	0.965	0.035
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.965	0.035
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.966	0.034
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.034	0.966	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.966	0.034
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.966	0.033
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.033	0.967	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.967	0.033
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.967	0.033
T42.3 Barbiturates	0.000	0.967	0.033
T42.2 Succinimides and oxazolidinediones	0.000	0.967	0.033
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.968	0.032
T37.5 Antiviral drugs	0.000	0.968	0.032
T37.4 Anthelminthics	0.000	0.968	0.032
T37.3 Other antiprotozoal drugs	0.000	0.968	0.032
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.968	0.032
T37.1 Antimycobacterial drugs	0.000	0.968	0.032
T37.0 Sulphonamides	0.000	0.968	0.032
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.968	0.032
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.968	0.032
T42.1 Iminostilbenes	0.000	0.969	0.031
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.969	0.031
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.969	0.031
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.969	0.031
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.969	0.031
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.969	0.031
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.969	0.031
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.969	0.031
T44.0 Anticholinesterase agents	0.000	0.969	0.031
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.031	0.969	0.000
T36.0 Penicillins	0.000	0.969	0.030
T41.5 Therapeutic gases	0.000	0.970	0.029
T41.4 Anaesthetic, unspecified	0.000	0.970	0.029
T41.3 Local anaesthetics	0.000	0.970	0.029
T41.2 Other and unspecified general anaesthetics	0.000	0.970	0.029
T41.1 Intravenous anaesthetics	0.000	0.970	0.029
T41.0 Inhaled anaesthetics	0.000	0.970	0.029
T45.0 Antiallergic and antiemetic drugs	0.000	0.971	0.029
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.971	0.029
T36.9 Systemic antibiotic, unspecified	0.000	0.972	0.028
T36.8 Other systemic antibiotics	0.000	0.972	0.028
T36.7 Antifungal antibiotics, systemically used	0.000	0.972	0.028
T36.6 Rifamycins	0.000	0.972	0.028
T36.5 Aminoglycosides	0.000	0.972	0.028
T36.2 Chloramphenicol group	0.000	0.972	0.028
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.972	0.028
T38.1 Thyroid hormones and substitutes	0.000	0.972	0.028
T49.9 Topical agent, unspecified	0.000	0.973	0.027
T49.8 Other topical agents	0.000	0.973	0.027
T49.7 Dental drugs, topically applied	0.000	0.973	0.027
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.973	0.027
T49.5 Ophthalmological drugs and preparations	0.000	0.973	0.027
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.973	0.027
T49.3 Emollients, demulcents and protectants	0.000	0.973	0.027
T49.2 Local astringents and local detergents	0.000	0.973	0.027
T49.1 Antipruritics	0.000	0.973	0.027
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.973	0.027
T48.5 Anti-common-cold drugs	0.000	0.973	0.027
T48.4 Expectorants	0.000	0.973	0.027
T48.3 Antitussives	0.000	0.973	0.027
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.973	0.027
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.973	0.027
T48.0 Oxytocic drugs	0.000	0.973	0.027
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.026	0.974	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.974	0.026
T36.3 Macrolides	0.000	0.974	0.026
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.974	0.025
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.974	0.025
T46.7 Peripheral vasodilators	0.000	0.974	0.025
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.974	0.025
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.974	0.025
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.974	0.025
J95.8 Other postprocedural respiratory disorders	0.000	0.974	0.026
T36.4 Tetracyclines	0.000	0.975	0.025
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.975	0.025
T45.8 Other primarily systemic and haematological agents	0.000	0.975	0.025
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.975	0.025
T45.6 Fibrinolysis-affecting drugs	0.000	0.975	0.025
T45.4 Iron and its compounds	0.000	0.975	0.025
T45.3 Enzymes, not elsewhere classified	0.000	0.975	0.025
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.975	0.024
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.975	0.024
T47.7 Emetics	0.000	0.975	0.024
T47.6 Antidiarrhoeal drugs	0.000	0.975	0.024
T47.5 Digestants	0.000	0.975	0.024
T47.4 Other laxatives	0.000	0.975	0.024
T47.3 Saline and osmotic laxatives	0.000	0.975	0.024
T47.2 Stimulant laxatives	0.000	0.975	0.024
T38.9 Other and unspecified hormone antagonists	0.000	0.976	0.024
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.976	0.024
T38.7 Androgens and anabolic congeners	0.000	0.976	0.024
T38.5 Other oestrogens and progestogens	0.000	0.976	0.024
T38.4 Oral contraceptives	0.000	0.976	0.024
T38.2 Antithyroid drugs	0.000	0.976	0.024
T38.0 Glucocorticoids and synthetic analogues	0.000	0.976	0.024
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.976	0.024
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.976	0.024
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.976	0.024
C78.2 Secondary malignant neoplasm of pleura	0.023	0.977	0.000
T46.1 Calcium-channel blockers	0.000	0.977	0.023
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.977	0.023
T45.2 Vitamins, not elsewhere classified	0.000	0.978	0.022
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.978	0.022
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.978	0.021
T47.0 Histamine H(2)-receptor antagonists	0.000	0.979	0.021
O72.1 Other immediate postpartum haemorrhage	0.021	0.979	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.980	0.020
T45.5 Anticoagulants	0.000	0.981	0.019
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.981	0.019
S40 Superficial injury of shoulder and upper arm	0.015	0.985	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.014	0.986	0.000
M54.39 Sciatica (Site unspecified)	0.014	0.986	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.987	0.012
S40.8 Other superficial injuries of shoulder and upper arm	0.012	0.988	0.000
S40.0 Contusion of shoulder and upper arm	0.011	0.988	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.011	0.989	0.000
N81.3 Complete uterovaginal prolapse	0.011	0.989	0.000
R68.8 Other specified general symptoms and signs	0.010	0.990	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.991	0.009
K83.8 Other specified diseases of biliary tract	0.000	0.991	0.009
O82.0 Delivery by elective Caesarean section	0.009	0.991	0.000
G93.3 Postviral fatigue syndrome	0.009	0.991	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.008	0.992	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.992	0.008
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.993	0.007
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.993	0.007
J95.5 Postprocedural subglottic stenosis	0.000	0.993	0.007
J95.4 Mendelson's syndrome	0.000	0.993	0.007
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.993	0.007
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.993	0.007
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.993	0.007
C80 Malignant neoplasm without specification of site	0.006	0.994	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.994	0.006
K92.1 Melaena	0.006	0.994	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.006	0.994	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.994	0.006
C76 Malignant neoplasm of other and ill-defined sites	0.006	0.994	0.000
R68 Other general symptoms and signs	0.006	0.994	0.000
J43.9 Emphysema, unspecified	0.000	0.994	0.006
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.005	0.995	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.005	0.995	0.000
R68.2 Dry mouth, unspecified	0.005	0.995	0.000
C76.0 Head, face and neck	0.005	0.995	0.000
J95.0 Tracheostomy malfunction	0.000	0.995	0.005
Z83.7 Family history of diseases of the digestive system	0.000	0.995	0.005
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.005	0.995	0.000
C77.5 Intrapelvic lymph nodes	0.005	0.995	0.000
C80.9 Malignant neoplasm, unspecified	0.005	0.995	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.004	0.996	0.000
C76.7 Other ill-defined sites	0.004	0.996	0.000
C76.5 Lower limb	0.004	0.996	0.000
C76.4 Upper limb	0.004	0.996	0.000
R68.3 Clubbing of fingers	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.004	0.996	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.004	0.996	0.000
C76.1 Thorax	0.004	0.996	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.004	0.996	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.996	0.004
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.004	0.996	0.000
C76.2 Abdomen	0.004	0.996	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.004	0.996	0.000
J43 Emphysema	0.000	0.996	0.004
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.004	0.996	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.004	0.996	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
C79 Secondary malignant neoplasm of other sites	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.004	0.996	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.996	0.004
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.004	0.996	0.000
T88.5 Other complications of anaesthesia	0.000	0.996	0.004
T88.4 Failed or difficult intubation	0.000	0.996	0.004
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.996	0.004
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.003	0.996	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.003	0.996	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
M67.1 Other contracture of tendon (sheath)	0.004	0.996	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.996	0.004
J43.2 Centrilobular emphysema	0.000	0.996	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.996	0.000
C83.1 Small cleaved cell (diffuse)	0.003	0.996	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.996	0.004
I69.3 Sequelae of cerebral infarction	0.004	0.996	0.000
O82.9 Delivery by Caesarean section, unspecified	0.003	0.996	0.000
C79.2 Secondary malignant neoplasm of skin	0.003	0.997	0.000
J43.8 Other emphysema	0.000	0.997	0.003
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.003	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.003	0.997	0.000
D47.4 Osteomyelofibrosis	0.000	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
C76.3 Pelvis	0.003	0.997	0.001
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.997	0.003
J43.1 Panlobular emphysema	0.000	0.997	0.003
J43.0 MacLeod's syndrome	0.000	0.997	0.003
T88.9 Complication of surgical and medical care, unspecified	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.997	0.003
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.997	0.003
T88.0 Infection following immunisation	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.003	0.997	0.000
T88.2 Shock due to anaesthesia	0.000	0.997	0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.5 Postradiation scoliosis	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
C83.0 Small cell (diffuse)	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
C77.0 Lymph nodes of head, face and neck	0.003	0.997	0.000
O72 Postpartum haemorrhage	0.003	0.997	0.000
W19.2 School, other institution and public administrative area	0.000	0.997	0.003
M48.02 Spinal stenosis (Cervical region)	0.000	0.997	0.003
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.997	0.003
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
D37.5 Rectum	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.003	0.997	0.000
C79.6 Secondary malignant neoplasm of ovary	0.003	0.997	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.003	0.997	0.000
Y40.0 Penicillins	0.000	0.997	0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.997	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.997	0.002
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
J35.1 Hypertrophy of tonsils	0.002	0.998	0.000
Z74.0 Reduced mobility	0.000	0.998	0.002
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
O72.3 Postpartum coagulation defects	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.998	0.002
N20.1 Calculus of ureter	0.002	0.998	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
K83 Other diseases of biliary tract	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
D06.9 Cervix, unspecified	0.000	0.998	0.002
J35.2 Hypertrophy of adenoids	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
R14 Flatulence and related conditions	0.000	0.998	0.002
D37.3 Appendix	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
F20 Schizophrenia	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.000	0.998	0.002
D18.1 Lymphangioma, any site	0.002	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
K83.5 Biliary cyst	0.000	0.998	0.002
K83.2 Perforation of bile duct	0.000	0.998	0.002
R30.0 Dysuria	0.000	0.998	0.002
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
J95-J99 Other diseases of the respiratory system	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
N90.7 Vulvar cyst	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.000	0.998	0.002
D40.0 Prostate	0.000	0.998	0.002
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.998	0.002
K09.9 Cyst of oral region, unspecified	0.000	0.998	0.002
K83.9 Disease of biliary tract, unspecified	0.000	0.998	0.002
D38.0 Larynx	0.000	0.998	0.001
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
J40 Bronchitis, not specified as acute or chronic	0.000	0.998	0.002
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.002	0.998	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.001
J20.9 Acute bronchitis, unspecified	0.000	0.998	0.002
J33.8 Other polyp of sinus	0.002	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.002	0.998	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.002	0.998	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.001	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.001	0.998	0.000
D37.1 Stomach	0.000	0.998	0.001
F20.8 Other schizophrenia	0.001	0.998	0.000
F20.6 Simple schizophrenia	0.001	0.998	0.000
F20.4 Postschizophrenic depression	0.001	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
K09 Cysts of oral region, not elsewhere classified	0.000	0.998	0.002
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.001
F20.5 Residual schizophrenia	0.001	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.998	0.001
C79.9 Secondary malignant neoplasm, unspecified site	0.001	0.998	0.000
D38.5 Other respiratory organs	0.000	0.998	0.001
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.001
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
J35 Chronic diseases of tonsils and adenoids	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.000	0.998	0.001
D38.4 Thymus	0.000	0.998	0.001
D38.3 Mediastinum	0.000	0.998	0.001
D38.2 Pleura	0.000	0.998	0.001
D44.0 Thyroid gland	0.000	0.998	0.001
J96 Respiratory failure, not elsewhere classified	0.000	0.998	0.001
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.001	0.999	0.000
I38 Endocarditis, valve unspecified	0.001	0.999	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
N41.1 Chronic prostatitis	0.000	0.999	0.001
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.999	0.001
E10.1 With ketoacidosis	0.000	0.999	0.001
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.999	0.001
J41 Simple and mucopurulent chronic bronchitis	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
U80.1 Methicillin resistant agent	0.001	0.999	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.999	0.001
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.999	0.001
S63.6 Sprain and strain of finger(s)	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
D37.9 Digestive organ, unspecified	0.000	0.999	0.001
D44.3 Pituitary gland	0.000	0.999	0.001
F25 Schizoaffective disorders	0.001	0.999	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
D40.1 Testis	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
M77.4 Metatarsalgia	0.001	0.999	0.000
B16 Acute hepatitis B	0.001	0.999	0.000
K40 Inguinal hernia	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.000	0.999	0.001
D40.7 Other male genital organs	0.000	0.999	0.001
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.999	0.001
L05.0 Pilonidal cyst with abscess	0.000	0.999	0.001
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.999	0.001
M45 Ankylosing spondylitis	0.000	0.999	0.001
A15.2 Tuberculosis of lung, confirmed histologically	0.001	0.999	0.000
C77.1 Intrathoracic lymph nodes	0.001	0.999	0.000
I05.0 Mitral stenosis	0.001	0.999	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.001	0.999	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.999	0.001
J41.0 Simple chronic bronchitis	0.000	0.999	0.001
J96.9 Respiratory failure, unspecified	0.000	0.999	0.001
J96.1 Chronic respiratory failure	0.000	0.999	0.001
J96.0 Acute respiratory failure	0.000	0.999	0.001
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.999	0.001
H27.8 Other specified disorders of lens	0.000	0.999	0.001
J35.8 Other chronic diseases of tonsils and adenoids	0.001	0.999	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.999	0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.001	0.999	0.000
M67.0 Short Achilles tendon (acquired)	0.001	0.999	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.999	0.001
J41.1 Mucopurulent chronic bronchitis	0.000	0.999	0.001
J44.8 Other specified chronic obstructive pulmonary disease	0.001	0.999	0.000
M67.4 Ganglion	0.001	0.999	0.000
Z20 Contact with and exposure to communicable diseases	0.001	0.999	0.000
D37.7 Other digestive organs	0.000	0.999	0.001
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.999	0.001
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.999	0.001
M67 Other disorders of synovium and tendon	0.001	0.999	0.000
M60.08 Infective myositis (Other)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.999	0.001
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
X47.0 Home	0.001	0.999	0.000
M77.49 Metatarsalgia-Site unspec	0.001	0.999	0.000
M77.48 Metatarsalgia-Other	0.001	0.999	0.000
M77.46 Metatarsalgia-Lower Leg	0.001	0.999	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.001	0.999	0.000
M77.44 Metatarsalgia-Hand	0.001	0.999	0.000
M77.43 Metatarsalgia-Forearm	0.001	0.999	0.000
M77.42 Metatarsalgia-Upper arm	0.001	0.999	0.000
M77.41 Metatarsalgia-Shldr region	0.001	0.999	0.000
M77.40 Metatarsalgia-Mult sites	0.001	0.999	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.001	0.999	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.001	0.999	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.001	0.999	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.001	0.999	0.000
D39.1 Ovary	0.000	0.999	0.001
D44.4 Craniopharyngeal duct	0.000	0.999	0.001
F60.9 Personality disorder, unspecified	0.000	0.999	0.001
K40.1 Bilateral inguinal hernia, with gangrene	0.001	0.999	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.999	0.001
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.999	0.001
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.999	0.001
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.999	0.001
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.999	0.001
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
K83.1 Obstruction of bile duct	0.000	0.999	0.001
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.999	0.001
J96.09 Acute respiratory failure; Type unspecified	0.000	0.999	0.001
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.000	0.999	0.001
J96.00 Acute respiratory failure; Type I [hypoxic]	0.000	0.999	0.001
J96.19 Chronic respiratory failure; Type unspecified	0.000	0.999	0.001
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.000	0.999	0.001
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.000	0.999	0.001
J96.99 Respiratory failure, unspecified; Type unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations