TreeWAS – Variant ID: rs488884

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.788	0.212
C79 Secondary malignant neoplasm of other sites	0.000	0.802	0.198
C79.6 Secondary malignant neoplasm of ovary	0.000	0.812	0.188
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.818	0.182
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.844	0.156
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.846	0.154
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.852	0.148
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.855	0.145
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.857	0.143
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.892	0.108
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.895	0.105
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.896	0.104
C76.0 Head, face and neck	0.000	0.897	0.103
C76.3 Pelvis	0.000	0.914	0.086
C80 Malignant neoplasm without specification of site	0.000	0.917	0.083
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.925	0.075
C76.7 Other ill-defined sites	0.000	0.925	0.075
C76.5 Lower limb	0.000	0.925	0.075
C76.4 Upper limb	0.000	0.925	0.075
C76.2 Abdomen	0.000	0.927	0.073
C79.2 Secondary malignant neoplasm of skin	0.000	0.928	0.072
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.069	0.931	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.933	0.067
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.933	0.067
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.935	0.065
C76.1 Thorax	0.000	0.936	0.064
L57 Skin changes due to chronic exposure to nonionising radiation	0.061	0.939	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.942	0.058
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.944	0.056
L57.4 Cutis laxa senilis	0.055	0.945	0.000
L57.0 Actinic keratosis	0.052	0.948	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.948	0.052
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.949	0.051
T42.4 Benzodiazepines	0.000	0.949	0.051
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.049	0.951	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.951	0.049
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.953	0.047
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.953	0.047
L57.5 Actinic granuloma	0.044	0.956	0.000
L57.3 Poikiloderma of Civatte	0.044	0.956	0.000
L57.2 Cutis rhomboidalis nuchae	0.044	0.956	0.000
L57.1 Actinic reticuloid	0.044	0.956	0.000
T42.1 Iminostilbenes	0.000	0.956	0.044
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.958	0.042
T42.3 Barbiturates	0.000	0.962	0.038
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.962	0.038
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.963	0.037
T42.2 Succinimides and oxazolidinediones	0.000	0.963	0.037
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.963	0.037
T42.0 Hydantoin derivatives	0.000	0.966	0.034
M19.97 Arthrosis, unspecified (Ankle and foot)	0.032	0.968	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.031	0.969	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.970	0.030
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.978	0.022
K43 Ventral hernia	0.021	0.979	0.000
F31 Bipolar affective disorder	0.000	0.979	0.021
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.980	0.020
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.980	0.020
F31.9 Bipolar affective disorder, unspecified	0.000	0.980	0.020
C78.2 Secondary malignant neoplasm of pleura	0.000	0.980	0.020
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.981	0.019
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.981	0.019
K43.9 Ventral hernia without obstruction or gangrene	0.019	0.981	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.982	0.018
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.982	0.018
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.982	0.018
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.982	0.018
T46.1 Calcium-channel blockers	0.000	0.983	0.017
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.983	0.017
T39.1 4-Aminophenol derivatives	0.000	0.984	0.016
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.984	0.016
K43.1 Ventral hernia with gangrene	0.016	0.984	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.984	0.016
K43.7 Other and unspecified ventral hernia with gangrene	0.015	0.985	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.015	0.985	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.015	0.985	0.000
K43.4 Parastomal hernia with gangrene	0.015	0.985	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.015	0.985	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.015	0.985	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.985	0.015
T39.0 Salicylates	0.000	0.985	0.015
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.985	0.015
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.985	0.015
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.985	0.015
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.985	0.014
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.986	0.014
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.986	0.014
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.986	0.014
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.986	0.014
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.986	0.014
T46.7 Peripheral vasodilators	0.000	0.986	0.014
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.986	0.014
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.986	0.014
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.986	0.014
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.986	0.014
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.986	0.013
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.987	0.013
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.987	0.013
T39.4 Antirheumatics, not elsewhere classified	0.000	0.987	0.013
T39.2 Pyrazolone derivatives	0.000	0.987	0.013
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.987	0.013
T36 Poisoning by systemic antibiotics	0.000	0.987	0.013
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.987	0.013
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.987	0.013
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.012	0.987	0.001
F31.8 Other bipolar affective disorders	0.000	0.987	0.013
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.987	0.013
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.988	0.012
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.988	0.012
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.988	0.012
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.988	0.012
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.988	0.012
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.988	0.012
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.988	0.012
T44.0 Anticholinesterase agents	0.000	0.988	0.012
T38.1 Thyroid hormones and substitutes	0.000	0.988	0.012
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.988	0.012
T47.0 Histamine H(2)-receptor antagonists	0.000	0.988	0.012
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.988	0.011
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.988	0.012
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.989	0.011
T41.5 Therapeutic gases	0.000	0.989	0.011
T41.4 Anaesthetic, unspecified	0.000	0.989	0.011
T41.3 Local anaesthetics	0.000	0.989	0.011
T41.2 Other and unspecified general anaesthetics	0.000	0.989	0.011
T41.1 Intravenous anaesthetics	0.000	0.989	0.011
T41.0 Inhaled anaesthetics	0.000	0.989	0.011
T49.9 Topical agent, unspecified	0.000	0.989	0.011
T49.8 Other topical agents	0.000	0.989	0.011
T49.7 Dental drugs, topically applied	0.000	0.989	0.011
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.989	0.011
T49.5 Ophthalmological drugs and preparations	0.000	0.989	0.011
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.989	0.011
T49.3 Emollients, demulcents and protectants	0.000	0.989	0.011
T49.2 Local astringents and local detergents	0.000	0.989	0.011
T49.1 Antipruritics	0.000	0.989	0.011
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.989	0.010
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.989	0.010
T47.7 Emetics	0.000	0.989	0.010
T47.6 Antidiarrhoeal drugs	0.000	0.989	0.010
T47.5 Digestants	0.000	0.989	0.010
T47.3 Saline and osmotic laxatives	0.000	0.989	0.010
T47.2 Stimulant laxatives	0.000	0.989	0.010
T50.7 Analeptics and opioid receptor antagonists	0.000	0.989	0.010
T50.5 Appetite depressants	0.000	0.989	0.010
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.989	0.010
T50.1 Loop [high-ceiling] diuretics	0.000	0.989	0.010
T50.0 Mineralocorticoids and their antagonists	0.000	0.989	0.010
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.989	0.010
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.990	0.010
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.990	0.010
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.990	0.010
T37.5 Antiviral drugs	0.000	0.990	0.010
T37.4 Anthelminthics	0.000	0.990	0.010
T37.3 Other antiprotozoal drugs	0.000	0.990	0.010
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.990	0.010
T37.1 Antimycobacterial drugs	0.000	0.990	0.010
T37.0 Sulphonamides	0.000	0.990	0.010
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.990	0.010
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.990	0.010
T38.9 Other and unspecified hormone antagonists	0.000	0.990	0.010
T38.7 Androgens and anabolic congeners	0.000	0.990	0.010
T38.5 Other oestrogens and progestogens	0.000	0.990	0.010
T38.4 Oral contraceptives	0.000	0.990	0.010
T38.2 Antithyroid drugs	0.000	0.990	0.010
T38.0 Glucocorticoids and synthetic analogues	0.000	0.990	0.010
T50.8 Diagnostic agents	0.000	0.990	0.010
L90.5 Scar conditions and fibrosis of skin	0.010	0.990	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.990	0.009
T36.8 Other systemic antibiotics	0.000	0.990	0.009
T36.7 Antifungal antibiotics, systemically used	0.000	0.990	0.009
T36.6 Rifamycins	0.000	0.990	0.009
T36.5 Aminoglycosides	0.000	0.990	0.009
T36.3 Macrolides	0.000	0.990	0.009
T36.2 Chloramphenicol group	0.000	0.990	0.009
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.990	0.009
L58 Radiodermatitis	0.009	0.990	0.001
T47.4 Other laxatives	0.000	0.990	0.009
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.990	0.009
L55 Sunburn	0.009	0.990	0.001
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.990	0.009
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.991	0.009
T48.4 Expectorants	0.000	0.991	0.009
T48.3 Antitussives	0.000	0.991	0.009
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.991	0.009
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.991	0.009
T48.0 Oxytocic drugs	0.000	0.991	0.009
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.991	0.009
T40.6 Other and unspecified narcotics	0.000	0.991	0.009
T43.6 Psychostimulants with abuse potential	0.000	0.991	0.009
T36.4 Tetracyclines	0.000	0.991	0.009
T50.4 Drugs affecting uric acid metabolism	0.000	0.991	0.009
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.991	0.009
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.991	0.009
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.991	0.009
T43.9 Psychotropic drug, unspecified	0.000	0.991	0.009
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.008	0.991	0.001
T36.0 Penicillins	0.000	0.991	0.008
T48.5 Anti-common-cold drugs	0.000	0.991	0.008
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.992	0.008
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.992	0.008
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.992	0.008
T40.1 Heroin	0.000	0.992	0.008
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.992	0.007
T40.8 Lysergide [LSD]	0.000	0.992	0.007
T40.7 Cannabis (derivatives)	0.000	0.992	0.007
T40.3 Methadone	0.000	0.992	0.007
T40.0 Opium	0.000	0.992	0.007
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.993	0.007
L58.9 Radiodermatitis, unspecified	0.007	0.993	0.001
L56 Other acute skin changes due to ultraviolet radiation	0.004	0.993	0.003
L58.1 Chronic radiodermatitis	0.007	0.993	0.001
L58.0 Acute radiodermatitis	0.007	0.993	0.001
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.993	0.007
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
L55.9 Sunburn, unspecified	0.007	0.993	0.001
L55.8 Other sunburn	0.007	0.993	0.001
L55.2 Sunburn of third degree	0.007	0.993	0.001
L55.1 Sunburn of second degree	0.007	0.993	0.001
L55.0 Sunburn of first degree	0.007	0.993	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.993	0.007
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.993	0.006
T45.8 Other primarily systemic and haematological agents	0.000	0.993	0.006
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.993	0.006
T45.6 Fibrinolysis-affecting drugs	0.000	0.993	0.006
T45.4 Iron and its compounds	0.000	0.993	0.006
T45.3 Enzymes, not elsewhere classified	0.000	0.993	0.006
H52.0 Hypermetropia	0.000	0.993	0.007
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.006	0.993	0.001
L59.0 Erythema ab igne [dermatitis ab igne]	0.006	0.993	0.001
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.006	0.994	0.000
T40.5 Cocaine	0.000	0.994	0.006
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.005	0.994	0.001
L56.3 Solar urticaria	0.003	0.995	0.003
L56.2 Photocontact dermatitis [berloque dermatitis]	0.003	0.995	0.003
L56.1 Drug photoallergic response	0.003	0.995	0.003
L56.0 Drug phototoxic response	0.003	0.995	0.003
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.995	0.004
L56.4 Polymorphous light eruption	0.003	0.995	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.995	0.005
D32.9 Meninges, unspecified	0.000	0.995	0.005
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.995	0.005
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.001	0.995	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.995	0.004
T40.4 Other synthetic narcotics	0.000	0.995	0.004
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
H52 Disorders of refraction and accommodation	0.000	0.995	0.005
J86.9 Pyothorax without fistula	0.005	0.995	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.995	0.005
N28.1 Cyst of kidney, acquired	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.004
T45.5 Anticoagulants	0.000	0.996	0.004
H52.7 Disorder of refraction, unspecified	0.000	0.996	0.004
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
H52.2 Astigmatism	0.000	0.996	0.004
D32.0 Cerebral meninges	0.000	0.996	0.004
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
D33.3 Cranial nerves	0.000	0.996	0.004
I85.9 Oesophageal varices without bleeding	0.004	0.996	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
D33.2 Brain, unspecified	0.000	0.996	0.004
D33.0 Brain, supratentorial	0.000	0.996	0.004
H52.1 Myopia	0.000	0.996	0.004
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.996	0.004
Y40 Systemic antibiotics	0.000	0.996	0.004
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.996	0.004
D32 Benign neoplasm of meninges	0.000	0.996	0.004
Y40.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
N28 Other disorders of kidney and ureter, not elsewhere classified	0.004	0.996	0.000
H52.6 Other disorders of refraction	0.000	0.996	0.003
H52.5 Disorders of accommodation	0.000	0.996	0.003
T40.2 Other opioids	0.000	0.996	0.004
G24.9 Dystonia, unspecified	0.000	0.996	0.004
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.996	0.004
Q61.4 Renal dysplasia	0.003	0.996	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.003	0.997	0.000
Y40.3 Macrolides	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
Y40.6 Rifamycins	0.000	0.997	0.003
H52.3 Anisometropia and aniseikonia	0.000	0.997	0.003
N28.0 Ischaemia and infarction of kidney	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
D33.4 Spinal cord	0.000	0.997	0.003
R47.0 Dysphasia and aphasia	0.000	0.997	0.003
W25.9 Unspecified place	0.000	0.997	0.003
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.997	0.003
H52.4 Presbyopia	0.000	0.997	0.003
K45 Other abdominal hernia	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
D33.9 Central nervous system, unspecified	0.000	0.997	0.003
D33.7 Other specified parts of central nervous system	0.000	0.997	0.003
D33.1 Brain, infratentorial	0.000	0.997	0.003
I98.2 Oesophageal varices in diseases classified elsewhere	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.000	0.997	0.003
Y45.8 Other analgesics and antipyretics	0.000	0.997	0.003
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.997	0.003
K41 Femoral hernia	0.003	0.997	0.000
Y40.4 Tetracyclines	0.000	0.997	0.003
Y57.8 Other drugs and medicaments	0.000	0.997	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.997	0.003
K40-K46 Hernia	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.000	0.997	0.002
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.002	0.997	0.000
N95.1 Menopausal and female climacteric states	0.000	0.997	0.002
K45.1 Other specified abdominal hernia with gangrene	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
J86 Pyothorax	0.002	0.998	0.000
D32.1 Spinal meninges	0.000	0.998	0.002
Y45.1 Salicylates	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.000	0.998	0.002
K41.1 Bilateral femoral hernia, with gangrene	0.002	0.998	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.998	0.002
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.998	0.002
Y45.4 Antirheumatics	0.000	0.998	0.002
L90 Atrophic disorders of skin	0.002	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.002	0.998	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.002
I47.2 Ventricular tachycardia	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
Y40.0 Penicillins	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.002	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
L90.8 Other atrophic disorders of skin	0.002	0.998	0.000
J85.2 Abscess of lung without pneumonia	0.002	0.998	0.000
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
L90.6 Striae atrophicae	0.002	0.998	0.000
L90.4 Acrodermatitis chronica atrophicans	0.002	0.998	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.002	0.998	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.002	0.998	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.002	0.998	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
L90.9 Atrophic disorder of skin, unspecified	0.002	0.998	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.998	0.002
N95 Menopausal and other perimenopausal disorders	0.000	0.998	0.002
D21.9 Connective and other soft tissue, unspecified	0.002	0.998	0.000
K52.3 Indeterminate colitis	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
R63.1 Polydipsia	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.002
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.998	0.001
J85 Abscess of lung and mediastinum	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.998	0.002
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
B44.1 Other pulmonary aspergillosis	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
Z43.3 Attention to colostomy	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.001	0.998	0.000
S61.7 Multiple open wounds of wrist and hand	0.002	0.998	0.000
N82.4 Other female intestinal-genital tract fistulae	0.001	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.001
L83 Acanthosis nigricans	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.001	0.998	0.000
G41.9 Status epilepticus, unspecified	0.000	0.998	0.002
J86.0 Pyothorax with fistula	0.001	0.998	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.998	0.001
G24 Dystonia	0.000	0.998	0.002
D21.6 Connective and other soft tissue of trunk, unspecified	0.001	0.998	0.000
Y45.2 Propionic acid derivatives	0.000	0.998	0.001
W25 Contact with sharp glass	0.000	0.998	0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
G24.8 Other dystonia	0.000	0.998	0.001
N82.0 Vesicovaginal fistula	0.001	0.998	0.000
N82 Fistulae involving female genital tract	0.001	0.998	0.000
N95.3 States associated with artificial menopause	0.000	0.999	0.001
R23.8 Other and unspecified skin changes	0.000	0.999	0.001
Y46.4 Iminostilbenes	0.000	0.999	0.001
D21.0 Connective and other soft tissue of head, face and neck	0.001	0.999	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.001	0.999	0.000
M25.86 Other specified joint disorders (Lower leg)	0.001	0.999	0.000
H05.2 Exophthalmic conditions	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
J85.3 Abscess of mediastinum	0.001	0.999	0.000
K38.1 Appendicular concretions	0.000	0.999	0.001
N82.9 Female genital tract fistula, unspecified	0.001	0.999	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
Y57.7 Vitamins, not elsewhere classified	0.000	0.999	0.001
Y57.4 Pharmaceutical excipients	0.000	0.999	0.001
Y57.3 Alcohol deterrents	0.000	0.999	0.001
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
Y57.1 Lipotropic drugs	0.000	0.999	0.001
Y57.0 Appetite depressants [anorectics]	0.000	0.999	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.999	0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
Y41.4 Anthelminthics	0.000	0.999	0.001
Y41.3 Other antiprotozoal drugs	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.000	0.999	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.999	0.001
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.999	0.001
Z75.0 Medical services not available in home	0.000	0.999	0.001
D21.4 Connective and other soft tissue of abdomen	0.001	0.999	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.999	0.001
O36.5 Maternal care for poor foetal growth	0.000	0.999	0.001
R23.4 Changes in skin texture	0.000	0.999	0.001
T59.8 Other specified gases, fumes and vapours	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.000	0.999	0.001
G24.0 Drug-induced dystonia	0.000	0.999	0.001
H49.1 Fourth [trochlear] nerve palsy	0.000	0.999	0.001
J85.0 Gangrene and necrosis of lung	0.001	0.999	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
G24.4 Idiopathic orofacial dystonia	0.000	0.999	0.001
G24.2 Idiopathic nonfamilial dystonia	0.000	0.999	0.001
J85.1 Abscess of lung with pneumonia	0.001	0.999	0.000
N85.4 Malposition of uterus	0.000	0.999	0.001
Y41.0 Sulphonamides	0.000	0.999	0.001
D21 Other benign neoplasms of connective and other soft tissue	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
W25.6 Industrial and construction area	0.000	0.999	0.001
W25.5 Trade and service area	0.000	0.999	0.001
W25.1 Residential institution	0.000	0.999	0.001
W25.0 Home	0.000	0.999	0.001
W25.7 Farm	0.000	0.999	0.001
W25.4 Street and highway	0.000	0.999	0.001
W25.3 Sports and athletics area	0.000	0.999	0.001
W25.2 School, other institution and public administrative area	0.000	0.999	0.001
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.999	0.001
M25.83 Other specified joint disorders (Forearm)	0.001	0.999	0.000
N82.5 Female genital tract-skin fistulae	0.001	0.999	0.000
N82.2 Fistula of vagina to small intestine	0.001	0.999	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.999	0.001
W25.8 Other specified place	0.000	0.999	0.001
Y54.0 Mineralocorticoids	0.000	0.999	0.001
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.999	0.001
I98 Other disorders of circulatory system in diseases classified elsewhere	0.001	0.999	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.999	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.999	0.001
J21.9 Acute bronchiolitis, unspecified	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Y46.8 Antispasticity drugs	0.000	0.999	0.001
Y46.3 Deoxybarbiturates	0.000	0.999	0.001
Y46.1 Oxazolidinediones	0.000	0.999	0.001
Y46.0 Succinimides	0.000	0.999	0.001
K46 Unspecified abdominal hernia	0.001	0.999	0.000
R34 Anuria and oliguria	0.001	0.999	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.001	0.999	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
N82.1 Other female urinary-genital tract fistulae	0.001	0.999	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.999	0.001
U80.1 Methicillin resistant agent	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.000	0.999	0.001
Y56.3 Emollients, demulcents and protectants	0.000	0.999	0.001
Y58 Bacterial vaccines	0.000	0.999	0.001
M25.84 Other specified joint disorders (Hand)	0.001	0.999	0.000
Y46.5 Valproic acid	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.999	0.001
N82.8 Other female genital tract fistulae	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations