TreeWAS – Variant ID: rs4889009

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.9 Non-toxic goitre, unspecified	0.000	0.810	0.190
E04 Other non-toxic goitre	0.000	0.813	0.187
E04.2 Non-toxic multinodular goitre	0.000	0.821	0.179
E05.9 Thyrotoxicosis, unspecified	0.000	0.824	0.176
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.824	0.176
E00-E07 Disorders of thyroid gland	0.000	0.827	0.173
E05.8 Other thyrotoxicosis	0.000	0.848	0.152
E07 Other disorders of thyroid	0.000	0.859	0.141
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.861	0.139
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.865	0.135
E04.8 Other specified non-toxic goitre	0.000	0.866	0.134
E04.0 Non-toxic diffuse goitre	0.000	0.871	0.129
E05.5 Thyroid crisis or storm	0.000	0.873	0.126
E05.4 Thyrotoxicosis factitia	0.000	0.873	0.126
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.873	0.126
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.876	0.124
E00 Congenital iodine-deficiency syndrome	0.000	0.876	0.124
E07.8 Other specified disorders of thyroid	0.000	0.884	0.116
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.885	0.115
E04.1 Non-toxic single thyroid nodule	0.000	0.892	0.108
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.893	0.107
E07.9 Disorder of thyroid, unspecified	0.000	0.895	0.105
E03 Other hypothyroidism	0.000	0.898	0.102
E07.1 Dyshormogenetic goitre	0.000	0.899	0.101
E07.0 Hypersecretion of calcitonin	0.000	0.899	0.101
E06 Thyroiditis	0.000	0.905	0.094
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.911	0.089
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.911	0.089
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.911	0.089
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.911	0.089
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.911	0.089
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.911	0.089
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.911	0.089
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.911	0.089
E03.8 Other specified hypothyroidism	0.000	0.912	0.088
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.921	0.079
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.926	0.074
E03.5 Myxoedema coma	0.000	0.927	0.073
E03.4 Atrophy of thyroid (acquired)	0.000	0.927	0.073
E03.3 Postinfectious hypothyroidism	0.000	0.927	0.073
E06.4 Drug-induced thyroiditis	0.000	0.932	0.068
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.932	0.068
E06.0 Acute thyroiditis	0.000	0.932	0.068
E06.5 Other chronic thyroiditis	0.000	0.933	0.066
E06.3 Autoimmune thyroiditis	0.000	0.934	0.066
E06.1 Subacute thyroiditis	0.000	0.934	0.065
E03.1 Congenital hypothyroidism without goitre	0.000	0.937	0.063
E06.9 Thyroiditis, unspecified	0.000	0.951	0.049
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.966	0.034
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.970	0.030
S20.8 Superficial injuries of other and unspecified parts of thorax	0.029	0.971	0.000
S20 Superficial injury of thorax	0.027	0.973	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.974	0.026
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.975	0.025
S20.2 Contusion of thorax	0.024	0.976	0.000
S27 Injury of other and unspecified intrathoracic organs	0.023	0.977	0.000
S20-S29 Injuries to the thorax	0.023	0.977	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.977	0.023
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.978	0.022
S27.2 Traumatic heamopneumothorax	0.022	0.978	0.000
S20.0 Contusion of breast	0.022	0.978	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.022	0.978	0.000
S20.1 Other and unspecified superficial injuries of breast	0.021	0.979	0.000
S29 Other and unspecified injuries of thorax	0.021	0.979	0.000
R10.2 Pelvic and perineal pain	0.000	0.979	0.021
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.980	0.020
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.980	0.020
S27.0 Traumatic pneumothorax	0.020	0.980	0.000
S20.7 Multiple superficial injuries of thorax	0.019	0.981	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.019	0.981	0.000
S29.9 Unspecified injury of thorax	0.019	0.981	0.000
S27.3 Other injuries of lung	0.018	0.982	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.018	0.982	0.000
S29.0 Injury of muscle and tendon at thorax level	0.018	0.982	0.000
S24 Injury of nerves and spinal cord at thorax level	0.017	0.983	0.000
S27.8 Injury of other specified intrathoracic organs	0.017	0.983	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.983	0.017
S20.3 Other superficial injuries of front wall of thorax	0.016	0.983	0.000
S21 Open wound of thorax	0.016	0.983	0.000
S27.9 Injury of unspecified intrathoracic organ	0.016	0.983	0.000
S27.7 Multiple injuries of intrathoracic organs	0.016	0.983	0.000
S27.6 Injury of pleura	0.016	0.983	0.000
S27.5 Injury of thoracic trachea	0.016	0.983	0.000
S27.4 Injury of bronchus	0.016	0.983	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.016	0.983	0.000
S26 Injury of heart	0.016	0.983	0.000
S25 Injury of blood vessels of thorax	0.016	0.983	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.984	0.016
S20.4 Other superficial injuries of back wall of thorax	0.016	0.984	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.016	0.984	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.016	0.984	0.000
S29.8 Other specified injuries of thorax	0.015	0.985	0.000
S29.7 Multiple injuries of thorax	0.015	0.985	0.000
H25.0 Senile incipient cataract	0.015	0.985	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.014	0.986	0.000
S27.1 Traumatic haemothorax	0.014	0.986	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.986	0.014
T50.9 Other and unspecified drugs, medicaments and biological substances	0.014	0.986	0.000
S21.1 Open wound of front wall of thorax	0.013	0.987	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.013	0.987	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.013	0.987	0.000
S21.0 Open wound of breast	0.013	0.987	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.013	0.987	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.013	0.987	0.000
S24.6 Injury of unspecified nerve of thorax	0.012	0.987	0.000
S24.5 Injury of other nerves of thorax	0.012	0.987	0.000
S24.4 Injury of thoracic sympathetic nerves	0.012	0.987	0.000
S24.3 Injury of peripheral nerves of thorax	0.012	0.987	0.000
S24.2 Injury of nerve root of thoracic spine	0.012	0.987	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.012	0.987	0.000
N45 Orchitis and epididymitis	0.000	0.988	0.012
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.012	0.988	0.000
S21.8 Open wound of other parts of thorax	0.012	0.988	0.000
S21.7 Multiple open wounds of thoracic wall	0.012	0.988	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.012	0.988	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.012	0.988	0.000
S25.8 Injury of other blood vessels of thorax	0.012	0.988	0.000
S25.7 Injury of multiple blood vessels of thorax	0.012	0.988	0.000
S25.5 Injury of intercostal blood vessels	0.012	0.988	0.000
S25.4 Injury of pulmonary blood vessels	0.012	0.988	0.000
S25.3 Injury of innominate or subclavian vein	0.012	0.988	0.000
S25.2 Injury of superior vena cava	0.012	0.988	0.000
S25.1 Injury of innominate or subclavian artery	0.012	0.988	0.000
S25.0 Injury of thoracic aorta	0.012	0.988	0.000
S26.9 Injury of heart, unspecified	0.012	0.988	0.000
S26.8 Other injuries of heart	0.012	0.988	0.000
S26.0 Injury of heart with haemopericardium	0.012	0.988	0.000
S28.1 Traumatic amputation of part of thorax	0.012	0.988	0.000
S28.0 Crushed chest	0.012	0.988	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.011	0.988	0.000
S23.3 Sprain and strain of thoracic spine	0.011	0.988	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.011	0.988	0.000
S23.1 Dislocation of thoracic vertebra	0.011	0.988	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.011	0.988	0.000
S21.2 Open wound of back wall of thorax	0.011	0.989	0.000
S23.4 Sprain and strain of ribs and sternum	0.011	0.989	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.010	0.989	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.989	0.011
S21.9 Open wound of thorax, part unspecified	0.010	0.989	0.000
C91.1 Chronic lymphocytic leukaemia	0.009	0.991	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.991	0.009
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.991	0.009
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.009	0.991	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.009	0.991	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.009	0.991	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.009	0.991	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.009	0.991	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.009	0.991	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.009	0.991	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.991	0.009
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.008	0.991	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.992	0.000
F31 Bipolar affective disorder	0.000	0.992	0.008
R82.9 Other and unspecified abnormal finding in urine	0.000	0.992	0.008
I70.2 Atherosclerosis of arteries of the extremities	0.008	0.992	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.993	0.007
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.993	0.007
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.007	0.993	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.993	0.007
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.993	0.007
T50.6 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.993	0.007
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.007	0.993	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.993	0.007
T36-T50 Poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
T42.4 Benzodiazepines	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.993	0.000
T50.5 Appetite depressants	0.006	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.993	0.000
M67.1 Other contracture of tendon (sheath)	0.007	0.993	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.993	0.007
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.993	0.007
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.993	0.006
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.994	0.006
M67.8 Other specified disorders of synovium and tendon	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
F31.8 Other bipolar affective disorders	0.000	0.994	0.006
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
K10.8 Other specified diseases of jaws	0.006	0.994	0.000
R82 Other abnormal findings in urine	0.000	0.994	0.006
S22 Fracture of rib(s), sternum and thoracic spine	0.006	0.994	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.994	0.006
F31.7 Bipolar affective disorder, currently in remission	0.000	0.994	0.006
M67 Other disorders of synovium and tendon	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
R32 Unspecified urinary incontinence	0.000	0.994	0.006
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
T42.3 Barbiturates	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
E89.1 Postprocedural hypoinsulinaemia	0.000	0.994	0.005
I70 Atherosclerosis	0.005	0.995	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.995	0.005
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.995	0.005
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.995	0.005
T42.5 Mixed antiepileptics, not elsewhere classified	0.005	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
M67.4 Ganglion	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
E89.5 Postprocedural testicular hypofunction	0.000	0.995	0.005
T47.4 Other laxatives	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
R82.1 Myoglobinuria	0.000	0.995	0.005
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
D34 Benign neoplasm of thyroid gland	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.995	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.995	0.005
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
V18.0 Driver injured in nontraffic accident	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.005	0.995	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
R82.4 Acetonuria	0.000	0.995	0.005
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.005	0.995	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.995	0.004
R82.3 Haemoglobinuria	0.000	0.995	0.004
R82.2 Biliuria	0.000	0.995	0.004
R82.0 Chyluria	0.000	0.995	0.004
S22.9 Fracture of bony thorax, part unspecified	0.004	0.995	0.000
S22.8 Fracture of other parts of bony thorax	0.004	0.995	0.000
M67.0 Short Achilles tendon (acquired)	0.004	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.004	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.995	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.995	0.000
M67.3 Transient synovitis	0.004	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.995	0.000
S22.5 Flail chest	0.004	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
B37.8 Candidiasis of other sites	0.004	0.996	0.000
I70.8 Atherosclerosis of other arteries	0.004	0.996	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.996	0.004
S22.0 Fracture of thoracic vertebra	0.004	0.996	0.000
I70.0 Atherosclerosis of aorta	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.000	0.996	0.004
T40.5 Cocaine	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
M67.43 Ganglion, wrist	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
K86 Other diseases of pancreas	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.004	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.004	0.996	0.000
M67.47 Ganglion, ankle and foot	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
K86.9 Disease of pancreas, unspecified	0.004	0.996	0.000
K86.1 Other chronic pancreatitis	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.996	0.004
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
M67.49 Ganglion, multiple sites	0.004	0.996	0.000
M67.45 Ganglion, hip	0.004	0.996	0.000
V18.5 Passenger injured in traffic accident	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.996	0.000
B44.9 Aspergillosis, unspecified	0.000	0.996	0.004
T36.4 Tetracyclines	0.003	0.996	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.003	0.996	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.003	0.996	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.003	0.996	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.003	0.996	0.000
B37.0 Candidal stomatitis	0.004	0.996	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.004	0.996	0.000
S19.9 Unspecified injury of neck	0.000	0.996	0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.003	0.996	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.996	0.000
S22.3 Fracture of rib	0.003	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.996	0.000
T45.4 Iron and its compounds	0.003	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.996	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
V18.3 Person injured while boarding or alighting	0.003	0.997	0.000
S22.01 Fracture of thoracic vertebra (open)	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
S22.50 Flail chest (closed)	0.003	0.997	0.000
V18.1 Passenger injured in nontraffic accident	0.003	0.997	0.000
B37 Candidiasis	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
B37.3 Candidiasis of vulva and vagina	0.003	0.997	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.003	0.997	0.000
V18.4 Driver injured in traffic accident	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.997	0.000
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
N48.1 Balanoposthitis	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.003	0.997	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.003	0.997	0.000
S56 Injury of muscle and tendon at forearm level	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.003	0.997	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
B37.1 Pulmonary candidiasis	0.003	0.997	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
B37.2 Candidiasis of skin and nail	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.997	0.003
V27.4 Driver injured in traffic accident	0.003	0.997	0.000
J38.4 Oedema of larynx	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
B37.6 Candidal endocarditis	0.002	0.997	0.000
B37.5 Candidal meningitis	0.002	0.997	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.997	0.003
S56.7 Injury of multiple muscles and tendons at forearm level	0.003	0.997	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.002	0.997	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.002	0.997	0.000
M11.2 Other chondrocalcinosis	0.000	0.997	0.003
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.997	0.000
D59.1 Other autoimmune haemolytic anaemias	0.003	0.997	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.997	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.997	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.997	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.997	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.997	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.997	0.000
G90.3 Multisystem degeneration	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.997	0.000
R59.9 Enlarged lymph nodes, unspecified	0.003	0.997	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.997	0.003
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
K22.1 Ulcer of oesophagus	0.000	0.998	0.002
S56.2 Injury of other flexor muscle and tendon at forearm level	0.002	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.002	0.998	0.000
B37.7 Candidal septicaemia	0.002	0.998	0.000
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.998	0.002
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
K62.3 Rectal prolapse	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
B44 Aspergillosis	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
R81 Glycosuria	0.000	0.998	0.002
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.002
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.002
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.002
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.002
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.002
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.002
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.002
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.998	0.002
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
B37.4 Candidiasis of other urogenital sites	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations